[go: up one dir, main page]

YU41993A - Postupak sferonizacije korišćenjem smole sa nabojem - Google Patents

Postupak sferonizacije korišćenjem smole sa nabojem

Info

Publication number
YU41993A
YU41993A YU41993A YU41993A YU41993A YU 41993 A YU41993 A YU 41993A YU 41993 A YU41993 A YU 41993A YU 41993 A YU41993 A YU 41993A YU 41993 A YU41993 A YU 41993A
Authority
YU
Yugoslavia
Prior art keywords
charge
resins
resin
spheronization
granulation
Prior art date
Application number
YU41993A
Other languages
English (en)
Inventor
G.A. Mcclelland
G.M. Zentner
Original Assignee
Merck & Co. Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc. filed Critical Merck & Co. Inc.
Publication of YU41993A publication Critical patent/YU41993A/sh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

POSTUPAK SFERONIZACIJE KORIŠĆENJEM SMOLE SA NABOJEM, otkriveno je da smole sa nabojem daju kvalitete granulaciji koji potpomažu dobijanje sfernih multičestičnosti postupkom sferonizacije. Kada se smole sa nabojem koriste, tada se mikrokristalna celuloza i drugi materijali koji su se ranije koristili za davanje plastičnosti granulaciji mogu izostaviti. Smole sa nabojem mogu da imaju dodatnu korisnost, što deluju da menjaju oslobađanje medikamenta iz smole iz izmenjenih sistema za uručivanje.
YU41993A 1992-06-26 1993-06-16 Postupak sferonizacije korišćenjem smole sa nabojem YU41993A (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/906,226 US5350584A (en) 1992-06-26 1992-06-26 Spheronization process using charged resins

Publications (1)

Publication Number Publication Date
YU41993A true YU41993A (sh) 1997-01-08

Family

ID=25422115

Family Applications (1)

Application Number Title Priority Date Filing Date
YU41993A YU41993A (sh) 1992-06-26 1993-06-16 Postupak sferonizacije korišćenjem smole sa nabojem

Country Status (9)

Country Link
US (1) US5350584A (sh)
EP (1) EP0804167A1 (sh)
JP (1) JP2793042B2 (sh)
CN (1) CN1081877A (sh)
AU (1) AU4542393A (sh)
CA (1) CA2136435A1 (sh)
TW (1) TW242115B (sh)
WO (1) WO1994000111A1 (sh)
YU (1) YU41993A (sh)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9203689D0 (en) * 1992-02-20 1992-04-08 Euro Celtique Sa Pharmaceutical composition
GB9310030D0 (en) * 1993-05-15 1993-06-30 Scras Dry processed particles and process for the preparation of the same
GB9505032D0 (en) * 1995-03-13 1995-05-03 Westminster Lab Ltd Improvements in or relating to organic compositions
GB9422154D0 (en) 1994-11-03 1994-12-21 Euro Celtique Sa Pharmaceutical compositions and method of producing the same
US5965161A (en) 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
JPH11514382A (ja) * 1995-11-02 1999-12-07 メルク フロスト カナダ アンド カンパニー 新規な湿粒法
WO1998025590A2 (de) * 1996-12-12 1998-06-18 Dds Drug Delivery Service Gesellschaft Zur Förderung Der Forschung In Pharmazeutischer Technologie Und Biopharmazie Mbh Zubereitung in form eines wahlweise wirkstoffhaltigen matrixmaterial-hilfsstoff compounds
US5980882A (en) * 1997-04-16 1999-11-09 Medeva Pharmaceuticals Manufacturing Drug-resin complexes stabilized by chelating agents
US20040029962A1 (en) * 1997-12-12 2004-02-12 Chih-Ming Chen HMG-COA reductase inhibitor extended release formulation
US5916595A (en) * 1997-12-12 1999-06-29 Andrx Pharmaceutials, Inc. HMG co-reductase inhibitor
US20060141036A1 (en) * 1997-12-12 2006-06-29 Andrx Labs Llc HMG-CoA reductase inhibitor extended release formulation
IT1298574B1 (it) * 1998-02-06 2000-01-12 Vectorpharma Int Composizioni farmaceutiche in forma di microparticelle a base polimerica ottenute mediante estrusione e sferonizzazione
UA69413C2 (uk) 1998-05-22 2004-09-15 Брістол-Майерс Сквібб Компані Фармацевтична композиція, яка містить серцевину та ентеросолюбільну оболонку, фармацевтична композиція у вигляді сфероїдальних гранул, спосіб одержання сфероїдальних гранул та спосіб одержання фармацевтичної композиції
US7122207B2 (en) * 1998-05-22 2006-10-17 Bristol-Myers Squibb Company High drug load acid labile pharmaceutical composition
UA73092C2 (uk) 1998-07-17 2005-06-15 Брістол-Майерс Сквібб Компані Таблетка з ентеросолюбільним покриттям і спосіб її приготування
DE19855440A1 (de) * 1998-12-01 2000-06-08 Basf Ag Verfahren zum Herstellen fester Darreichungsformen mittels Schmelzextrusion
DE19918325A1 (de) 1999-04-22 2000-10-26 Euro Celtique Sa Verfahren zur Herstellung von Arzneiformen mit regulierter Wirkstofffreisetzung mittels Extrusion
AU6381300A (en) * 1999-07-29 2001-02-19 Roxane Laboratories, Inc. Opioid sustained-released formulation
US20030225124A1 (en) * 1999-08-31 2003-12-04 Spiridon Spireas Stable formulations of ACE inhibitors, and methods for preparation thereof
US6555551B1 (en) 1999-08-31 2003-04-29 Mutual Pharmaceutical Co., Inc. Stable formulations of ACE inhibitors, and methods for preparation thereof
US6764694B1 (en) * 1999-08-31 2004-07-20 Mutual Pharmaceutical Co., Inc. Stable formulations of ACE inhibitors, and methods for preparation thereof
US20040157911A1 (en) * 1999-08-31 2004-08-12 Spiridon Spireas Storage-stable and bio-stable formulations of ace inhibitors, and methods for preparation thereof
DE10008506A1 (de) * 2000-02-24 2001-09-13 Bayer Ag Verfahren zur Herstellung von pharmazeutischen Darreichungsformen
USRE44578E1 (en) 2000-04-10 2013-11-05 Teva Pharmaceutical Industries, Ltd. Stable pharmaceutical compositions containing 7-substituted-3,5-dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids
IL152179A (en) * 2000-04-10 2009-06-15 Teva Pharma Stable pharmaceutical compositions containing 7-substituted-3,5- dihydroxyheptanoic acids or 7-substituted-3,5-dihydroxyheptenoic acids
WO2005041657A1 (en) 2003-10-20 2005-05-12 Framework Therapeutics, L.L.C. Zeolite molecular sieves for the removal of toxins
US7387793B2 (en) * 2003-11-14 2008-06-17 Eurand, Inc. Modified release dosage forms of skeletal muscle relaxants
DE102005042875A1 (de) * 2004-12-23 2006-09-21 Grünenthal GmbH Schnell freisetzende Darreichungsformen für Antibiotika
US8318230B2 (en) * 2005-05-02 2012-11-27 Henkel Ag & Co. Kgaa Use of debranched starch in extrusion-spheronization pharmaceutical pellets
EP2502621A1 (en) 2005-06-27 2012-09-26 Valeant International (Barbados) SRL Crystalline forms of bupropion HBr
US20090246276A1 (en) 2008-01-28 2009-10-01 Graham Jackson Pharmaceutical Compositions
CA2735962A1 (en) * 2008-09-02 2010-04-15 Usv Limited Crosslinked polymers
EP2621475A1 (en) 2010-10-02 2013-08-07 Link Research&Grants Corporation Treatment of tinnitus and related auditory dysfunctions
KR101890959B1 (ko) 2010-11-04 2018-08-22 알비레오 에이비 간질환 치료를 위한 ｉｂａｔ 억제제
US20120308895A1 (en) 2011-05-31 2012-12-06 General Electric Company Electrode compositions useful for energy storage devices and other applications; and related devices and processes
KR102560954B1 (ko) 2014-06-25 2023-07-31 이에이 파마 가부시키가이샤 고형 제제 및 그의 착색 방지 또는 착색 감소 방법
EP3012252A1 (en) 2014-10-24 2016-04-27 Ferring BV Crystal modifications of elobixibat
US10786529B2 (en) 2016-02-09 2020-09-29 Albireo Ab Oral cholestyramine formulation and use thereof
JP6830969B2 (ja) * 2016-02-09 2021-02-17 アルビレオ・アクチボラグ コレスチラミンペレット剤及びその調製のための方法
US10441604B2 (en) 2016-02-09 2019-10-15 Albireo Ab Cholestyramine pellets and methods for preparation thereof
US10441605B2 (en) 2016-02-09 2019-10-15 Albireo Ab Oral cholestyramine formulation and use thereof
CA3071182A1 (en) * 2017-08-09 2019-02-14 Albireo Ab Cholestyramine pellets, oral cholestyramine formulations and use thereof
WO2019032026A1 (en) 2017-08-09 2019-02-14 Albireo Ab CHOLESTYRAMINE GRANULES, ORAL FORMULATIONS OF CHOLESTYRAMINE AND THEIR USE
CN107552777A (zh) * 2017-09-05 2018-01-09 昆山玛冀电子有限公司 一种用于电感生产的粉末颗粒成分及生产工艺
AU2018360383A1 (en) 2017-11-02 2020-05-21 Natureceuticals Sdn. Bhd. Extract of orthosiphon stamineus, formulations, and uses thereof
TW202015699A (zh) 2018-06-05 2020-05-01 瑞典商艾爾比瑞歐公司 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽汁酸調節劑之用途
US10793534B2 (en) 2018-06-05 2020-10-06 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
JP7504032B2 (ja) 2018-06-20 2024-06-21 アルビレオ・アクチボラグ オデビキシバットの結晶変態
US11801226B2 (en) 2018-06-20 2023-10-31 Albireo Ab Pharmaceutical formulation of odevixibat
US11007142B2 (en) 2018-08-09 2021-05-18 Albireo Ab Oral cholestyramine formulation and use thereof
US10722457B2 (en) 2018-08-09 2020-07-28 Albireo Ab Oral cholestyramine formulation and use thereof
US11549878B2 (en) 2018-08-09 2023-01-10 Albireo Ab In vitro method for determining the adsorbing capacity of an insoluble adsorbant
US10975045B2 (en) 2019-02-06 2021-04-13 Aibireo AB Benzothiazepine compounds and their use as bile acid modulators
US10941127B2 (en) 2019-02-06 2021-03-09 Albireo Ab Benzothiadiazepine compounds and their use as bile acid modulators
SG11202108566VA (en) 2019-02-06 2021-09-29 Albireo Ab Benzothiadiazepine compounds and their use as bile acid modulators
CN114786772B (zh) 2019-12-04 2024-04-09 阿尔比里奥公司 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途
JP7665620B2 (ja) 2019-12-04 2025-04-21 アルビレオ・アクチボラグ ベンゾチアジアゼピン化合物及び胆汁酸モジュレータとしてのそれらの使用
CN114761080B (zh) 2019-12-04 2024-07-23 阿尔比里奥公司 苯并硫杂(二)氮杂环庚三烯化合物及其作为胆汁酸调节剂的用途
US11014898B1 (en) 2020-12-04 2021-05-25 Albireo Ab Benzothiazepine compounds and their use as bile acid modulators
BR112022010505A2 (pt) 2019-12-04 2022-09-06 Albireo Ab Compostos de benzotia(di)azepina e seu uso como moduladores do ácido biliar
CA3186857A1 (en) 2020-08-03 2022-02-10 Per-Goran Gillberg Benzothia(di)azepine compounds and their use as bile acid modulators
JP2023549226A (ja) 2020-11-12 2023-11-22 アルビレオ エービー 進行性家族性肝内胆汁うっ滞症（ｐｆｉｃ）を処置するためのオデビキシバット
BR112023010799A2 (pt) 2020-12-04 2023-10-03 Albireo Ab Compostos de benzotia(di)azepina e seus usos como moduladores de ácidos biliares
TW202313579A (zh) 2021-06-03 2023-04-01 瑞典商艾爾比瑞歐公司 苯并噻(二)氮呯(benzothia(di)azepine)化合物及其作為膽酸調節劑之用途

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB717840A (en) * 1951-09-22 1954-11-03 Ici Ltd Water-dispersible solid compositions
US3131121A (en) * 1960-10-31 1964-04-28 Hoffmann La Roche Highly acidic cation exchange resin containing amprotropine cations
JPS59500614A (ja) * 1982-04-23 1984-04-12 エイ／エス　アルフレツド　ベンツオン 消化機能調査用の組成物と方法
CA1236023A (en) * 1984-07-18 1988-05-03 Yegnaswami Raghunathan Controlled release pharmaceutical preparations
CA1264566A (en) * 1984-09-05 1990-01-23 Tetsuji Iwasaki Biocidal fine powder, its manufacturing method and a suspension for agricultural use containing the above powder
US4976949A (en) * 1985-10-25 1990-12-11 The University Of Michigan Controlled release dosage form
DE3775880D1 (sh) * 1986-09-18 1992-02-20 London School Of Pharmacy Innovations Ltd., London, Gb
US4808413A (en) * 1987-04-28 1989-02-28 E. R. Squibb & Sons, Inc. Pharmaceutical compositions in the form of beadlets and method
CA2002492A1 (en) * 1988-11-11 1990-05-11 Sandra T. A. Malkowska Pharmaceutical ion exchange resin composition

Also Published As

Publication number Publication date
EP0804167A4 (sh) 1997-11-05
EP0804167A1 (en) 1997-11-05
CA2136435A1 (en) 1994-01-06
WO1994000111A1 (en) 1994-01-06
JPH07508280A (ja) 1995-09-14
AU4542393A (en) 1994-01-24
US5350584A (en) 1994-09-27
TW242115B (sh) 1995-03-01
CN1081877A (zh) 1994-02-16
JP2793042B2 (ja) 1998-09-03

Similar Documents

Publication Publication Date Title
YU41993A (sh) Postupak sferonizacije korišćenjem smole sa nabojem
ES2060784T3 (es) Granulos que tienen un nucleo y su produccion.
MX9400166A (es) Microesferas de proteina vegetal, hidrolizada, modificada y metodos para su preparacion y su uso.
ES2182754T3 (es) Procedimiento para preparar comprimidos revestidos con polimero, que comprenden amoxicilina y clavulanato revestidos con un revestimiento polimero acuoso formador de pelicula.
PT100234A (pt) Novos esteres de alcoois aminados biciclicos e triciclicos, processo para a sua preparacao
DE60036874D1 (de) Pellet formulierung mit gesteuerter freisetzung
MX394584B (es) Preparación que comprende vonoprazán.
ES2042705T3 (es) Una composicion de revestimiento en polvo termoendurecible.
ES2061620T3 (es) Composicion de revestimiento en polvo termoendurecible.
DE69434258D1 (de) Mikroverkapselte 1,2-benzazole
KR910011242A (ko) 서방성 약학제제 및 그의 제조방법
SE9602442D0 (sv) Administration of pharmaceuticals
DK616186A (da) Farmaceutisk praeparat med retarderet frigivelse af ibuprofen
DK1167354T3 (da) Racemisk huperzin A
KR850001693A (ko) 아모술랄롤 하이드로클로라이드 지속성 제제의 제조방법
ES2113898T3 (es) Compuestos de imidazol, su fabricacion y utilizacion.
KR890003292A (ko) 안정화된 사료 첨가제 및 이의 제조방법
ITPD920142A1 (it) Esteri di gellano autoreticolato, procedimento di preparazione e loro applicazioni farmaceutiche e biomedico-sanitarie
ES2181685T3 (es) Metodos para producir eg iii celulasa, xilanasa o una mezcla de ambos usando polietilenglicol.
Han et al. Overview of mechanisms and novel therapies on rheumatoid arthritis from a cellular perspective
GB1243470A (en) Hairdressings
AU2366501A (en) Pharmaceutical composition comprised of spider venoms, the production thereof, and its use for treating tumor diseases
WO1997010810A3 (en) Pharmaceutical granules
KR880001732A (ko) 중합체-처리한 이온교환수지
AR033896A1 (es) Preparaciones granuladas de gaboxadol.