YU28002A - Farmaceutska kompozicija koja sadrži ciklesonid za primenu na sluzokoži - Google Patents
Farmaceutska kompozicija koja sadrži ciklesonid za primenu na sluzokožiInfo
- Publication number
- YU28002A YU28002A YU28002A YUP28002A YU28002A YU 28002 A YU28002 A YU 28002A YU 28002 A YU28002 A YU 28002A YU P28002 A YUP28002 A YU P28002A YU 28002 A YU28002 A YU 28002A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- mucosa
- application
- pharmaceutical composition
- ciclesonide
- contained pharmaceutical
- Prior art date
Links
- 210000004877 mucosa Anatomy 0.000 title abstract 4
- LUKZNWIVRBCLON-GXOBDPJESA-N Ciclesonide Chemical compound C1([C@H]2O[C@@]3([C@H](O2)C[C@@H]2[C@@]3(C[C@H](O)[C@@H]3[C@@]4(C)C=CC(=O)C=C4CC[C@H]32)C)C(=O)COC(=O)C(C)C)CCCCC1 LUKZNWIVRBCLON-GXOBDPJESA-N 0.000 title abstract 3
- 229960003728 ciclesonide Drugs 0.000 title abstract 3
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 3
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000002651 drug therapy Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000003204 osmotic effect Effects 0.000 abstract 1
- 230000035699 permeability Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 210000004876 tela submucosa Anatomy 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Ovaj pronalazak predlaže farmaceutsku kompoziciju za primenu na sluzokoži da se koristi u lečenju medikamentima koja sadrži u vodi nerastvorljivu i/ili u vodi slabo rastvorljivu supstancu, ciklesonid, i vodeni medijum, i koja ima osmotski pritisak koji je manji od 290 mOsm. Ta kompozicija je superioma u odnosu na konvencionalne farmaceutske kompozicije za primenu na sluzokoži, usled efikasne i velike retencije i prodornosti ciklesonida u submukozu ili krv u sluzokoži.[The present invention provides a pharmaceutical composition for application to the mucosa to be used in drug therapy comprising a water-insoluble and/or water-low soluble substance, ciclesonide, and an aqueous medium, and having an osmotic pressure of less than 290 mOsm. This composition is superior over conventional pharmaceutical compositions for application to the mucosa, due to efficient and high ciclesonide retentivity and permeability to the submucosa or the blood at the mucosa.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MEP-2008-856A ME00567B (me) | 1999-10-20 | 2000-10-20 | Farmaceutska kompozicija koja sadrži ciklesonid za primenu na sluzokoži |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP29818599 | 1999-10-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| YU28002A true YU28002A (sh) | 2004-11-25 |
| RS50310B RS50310B (sr) | 2009-09-08 |
Family
ID=17856327
Country Status (35)
| Country | Link |
|---|---|
| US (1) | US6767901B1 (sh) |
| EP (1) | EP1225902B1 (sh) |
| JP (1) | JP4264211B2 (sh) |
| KR (1) | KR100722209B1 (sh) |
| CN (2) | CN1379674B (sh) |
| AR (1) | AR026072A1 (sh) |
| AT (1) | ATE285779T1 (sh) |
| AU (1) | AU781895B2 (sh) |
| BG (1) | BG65818B1 (sh) |
| BR (1) | BRPI0014878B8 (sh) |
| CA (1) | CA2388322C (sh) |
| CO (1) | CO5261494A1 (sh) |
| CZ (1) | CZ297779B6 (sh) |
| DE (1) | DE60017175T2 (sh) |
| DK (1) | DK1225902T3 (sh) |
| EA (1) | EA006015B1 (sh) |
| ES (1) | ES2234681T3 (sh) |
| HR (1) | HRP20020346B1 (sh) |
| HU (1) | HU228893B1 (sh) |
| IL (2) | IL148691A0 (sh) |
| ME (1) | ME00567B (sh) |
| MX (1) | MXPA02003974A (sh) |
| MY (1) | MY136987A (sh) |
| NO (1) | NO327444B1 (sh) |
| NZ (1) | NZ518298A (sh) |
| PE (1) | PE20010712A1 (sh) |
| PL (1) | PL199702B1 (sh) |
| PT (1) | PT1225902E (sh) |
| RS (1) | RS50310B (sh) |
| SI (1) | SI1225902T1 (sh) |
| SK (1) | SK286196B6 (sh) |
| TR (1) | TR200200841T2 (sh) |
| TW (1) | TWI225788B (sh) |
| WO (1) | WO2001028562A1 (sh) |
| ZA (1) | ZA200203077B (sh) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR026073A1 (es) | 1999-10-20 | 2002-12-26 | Nycomed Gmbh | Composicion farmaceutica acuosa que contiene ciclesonida |
| AR026072A1 (es) * | 1999-10-20 | 2002-12-26 | Nycomed Gmbh | Composicion farmaceutica que contiene ciclesonida para aplicacion a la mucosa |
| WO2004004739A1 (en) * | 2002-07-02 | 2004-01-15 | Altana Pharma Ag | Ciclesonide-containing sterile aqueous suspension |
| US7221586B2 (en) | 2002-07-08 | 2007-05-22 | Micron Technology, Inc. | Memory utilizing oxide nanolaminates |
| AU2003261225A1 (en) * | 2002-07-26 | 2004-02-16 | Fmc Corporation | Production of microcrystalline cellulose |
| NZ538954A (en) * | 2002-08-30 | 2007-04-27 | Altana Pharma Ag | The use of the combination of ciclesonide and antihistamines for the treatment of allergic rhinitis and allergic conjunctivitis |
| EP1572217B1 (en) * | 2002-12-12 | 2008-08-20 | Nycomed GmbH | Combination medicament of r,r-formoterol and ciclesonide |
| MY143936A (en) | 2003-03-27 | 2011-07-29 | Nycomed Gmbh | Process for preparing crystalline ciclesonide with defined particle size |
| ES2452691T5 (es) | 2003-09-16 | 2022-09-14 | Covis Pharma Gmbh | Uso de ciclesonida para el tratamiento de enfermedades respiratorias |
| PE20050941A1 (es) * | 2003-12-16 | 2005-11-08 | Nycomed Gmbh | Suspensiones acuosas de ciclesonida para nebulizacion |
| WO2005102354A1 (en) * | 2004-04-20 | 2005-11-03 | Altana Pharma Ag | Use of ciclesonide for the treatment of respiratory diseases in a smoking patient |
| US20080027034A1 (en) * | 2004-09-10 | 2008-01-31 | Shah Tushar P | Ciclesonide and Syk Inhibitor Combination and Method of Use Thereof |
| EP1645266A1 (en) * | 2004-10-08 | 2006-04-12 | Hisamitsu Medical Co., Ltd. | Aqueous suspension for nasal drops |
| WO2009114192A2 (en) * | 2008-03-14 | 2009-09-17 | Cephalon, Inc. | Enhanced transmucosal composition and dosage form |
| WO2011135585A2 (en) | 2010-04-28 | 2011-11-03 | Cadila Healthcare Limited | Aqueous pharmaceutical solution of ciclesonide |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS63303931A (ja) * | 1987-06-05 | 1988-12-12 | Sumitomo Pharmaceut Co Ltd | 経鼻投与用成長ホルモン放出活性物質製剤 |
| GB9103824D0 (en) | 1991-02-23 | 1991-04-10 | Fisons Ag | Formulation |
| WO1997001337A1 (en) | 1995-06-29 | 1997-01-16 | Mcneil-Ppc, Inc. | The combination of topical nasal antihistamines and topical nasal steroids |
| US6120752A (en) * | 1997-05-21 | 2000-09-19 | 3M Innovative Properties Company | Medicinal aerosol products containing formulations of ciclesonide and related steroids |
| SE9704186D0 (sv) * | 1997-11-14 | 1997-11-14 | Astra Ab | New composition of matter |
| WO1999037286A1 (en) * | 1998-01-22 | 1999-07-29 | Santen Pharmaceutical Co., Ltd. | Fluorometholone suspension eye drops |
| SE514128C2 (sv) | 1998-03-17 | 2001-01-08 | Pharmalink Ab | Användning av en glukokortikoid för framställning av ett läkemedel för behandling av glomerulonefrit |
| TWI243687B (en) | 1998-04-21 | 2005-11-21 | Teijin Ltd | Pharmaceutical composition for application to mucosa |
| AR026072A1 (es) * | 1999-10-20 | 2002-12-26 | Nycomed Gmbh | Composicion farmaceutica que contiene ciclesonida para aplicacion a la mucosa |
-
2000
- 2000-10-18 AR ARP000105473A patent/AR026072A1/es not_active Application Discontinuation
- 2000-10-19 MY MYPI20004915A patent/MY136987A/en unknown
- 2000-10-19 PE PE2000001121A patent/PE20010712A1/es not_active IP Right Cessation
- 2000-10-19 CO CO00079610A patent/CO5261494A1/es active IP Right Grant
- 2000-10-19 TW TW089121994A patent/TWI225788B/zh not_active IP Right Cessation
- 2000-10-20 BR BRPI0014878A patent/BRPI0014878B8/pt not_active IP Right Cessation
- 2000-10-20 HU HU0203339A patent/HU228893B1/hu unknown
- 2000-10-20 US US10/110,629 patent/US6767901B1/en not_active Expired - Lifetime
- 2000-10-20 CN CN00814405.2A patent/CN1379674B/zh not_active Expired - Lifetime
- 2000-10-20 JP JP2001531392A patent/JP4264211B2/ja not_active Expired - Lifetime
- 2000-10-20 MX MXPA02003974A patent/MXPA02003974A/es active IP Right Grant
- 2000-10-20 CZ CZ20021238A patent/CZ297779B6/cs not_active IP Right Cessation
- 2000-10-20 TR TR2002/00841T patent/TR200200841T2/xx unknown
- 2000-10-20 EP EP00969966A patent/EP1225902B1/en not_active Expired - Lifetime
- 2000-10-20 SK SK692-2002A patent/SK286196B6/sk not_active IP Right Cessation
- 2000-10-20 DE DE60017175T patent/DE60017175T2/de not_active Expired - Lifetime
- 2000-10-20 CA CA002388322A patent/CA2388322C/en not_active Expired - Fee Related
- 2000-10-20 NZ NZ518298A patent/NZ518298A/en not_active IP Right Cessation
- 2000-10-20 EA EA200200375A patent/EA006015B1/ru not_active IP Right Cessation
- 2000-10-20 AT AT00969966T patent/ATE285779T1/de active
- 2000-10-20 AU AU79531/00A patent/AU781895B2/en not_active Expired
- 2000-10-20 ES ES00969966T patent/ES2234681T3/es not_active Expired - Lifetime
- 2000-10-20 HR HR20020346A patent/HRP20020346B1/xx not_active IP Right Cessation
- 2000-10-20 DK DK00969966T patent/DK1225902T3/da active
- 2000-10-20 PL PL356191A patent/PL199702B1/pl unknown
- 2000-10-20 ME MEP-2008-856A patent/ME00567B/me unknown
- 2000-10-20 RS YUP-280/02A patent/RS50310B/sr unknown
- 2000-10-20 SI SI200030622T patent/SI1225902T1/xx unknown
- 2000-10-20 CN CN2010102234335A patent/CN101869570B/zh not_active Expired - Lifetime
- 2000-10-20 KR KR1020027004995A patent/KR100722209B1/ko not_active Expired - Lifetime
- 2000-10-20 WO PCT/JP2000/007350 patent/WO2001028562A1/en not_active Ceased
- 2000-10-20 IL IL14869100A patent/IL148691A0/xx active IP Right Grant
- 2000-10-20 PT PT00969966T patent/PT1225902E/pt unknown
-
2002
- 2002-03-13 BG BG106512A patent/BG65818B1/bg unknown
- 2002-03-14 IL IL148691A patent/IL148691A/en unknown
- 2002-04-18 ZA ZA200203077A patent/ZA200203077B/xx unknown
- 2002-04-22 NO NO20021898A patent/NO327444B1/no not_active IP Right Cessation
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