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YU24501A - Esters of(+)-alpha-(2,3-dimethoxyphenyl)-1-(2-4fluorophenyl) ethyl)-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907 - Google Patents

Esters of(+)-alpha-(2,3-dimethoxyphenyl)-1-(2-4fluorophenyl) ethyl)-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907

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Publication number
YU24501A
YU24501A YU24501A YU24501A YU24501A YU 24501 A YU24501 A YU 24501A YU 24501 A YU24501 A YU 24501A YU 24501 A YU24501 A YU 24501A YU 24501 A YU24501 A YU 24501A
Authority
YU
Yugoslavia
Prior art keywords
esters
piperidinemethanol
dimethoxyphenyl
ethyl
prodrugs
Prior art date
Application number
YU24501A
Other languages
Serbo-Croatian (sh)
Inventor
Albert Carr
Hijfte Luc E. Van
Raymond W. Kosley Jr.
Original Assignee
Aventis Pharmaceuticals Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharmaceuticals Inc. filed Critical Aventis Pharmaceuticals Inc.
Priority to YU24501A priority Critical patent/YU24501A/en
Publication of YU24501A publication Critical patent/YU24501A/en

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Abstract

The present invention is directed to esters of (+)-α-(2,3-Dimethoxyphenyl)-1-[2-(4-lorophenyl)ethyl] -4-piperidinemethanol, of formula (I) wherein R is C4-C20alkyl, pharmaceutical formulations, methods of making and methods of using these esters. These compounds antagonize the effects of serotonin at the 5HT2A receptor and are useful in treating various conditions such as, for example, psychoses such as schizophrenia.
YU24501A 1998-10-14 1998-10-14 Esters of(+)-alpha-(2,3-dimethoxyphenyl)-1-(2-4fluorophenyl) ethyl)-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907 YU24501A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
YU24501A YU24501A (en) 1998-10-14 1998-10-14 Esters of(+)-alpha-(2,3-dimethoxyphenyl)-1-(2-4fluorophenyl) ethyl)-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
YU24501A YU24501A (en) 1998-10-14 1998-10-14 Esters of(+)-alpha-(2,3-dimethoxyphenyl)-1-(2-4fluorophenyl) ethyl)-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907

Publications (1)

Publication Number Publication Date
YU24501A true YU24501A (en) 2003-10-31

Family

ID=47720198

Family Applications (1)

Application Number Title Priority Date Filing Date
YU24501A YU24501A (en) 1998-10-14 1998-10-14 Esters of(+)-alpha-(2,3-dimethoxyphenyl)-1-(2-4fluorophenyl) ethyl)-4-piperidinemethanol and their use as prodrugs of the 5ht2a receptor antagonist mdl 110,907

Country Status (1)

Country Link
YU (1) YU24501A (en)

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