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YU14392A - Derivati imidazopiridina, postupak za dobijanje smeša sa njima i postupak za dobijanje derivata imidazopiridina - Google Patents

Derivati imidazopiridina, postupak za dobijanje smeša sa njima i postupak za dobijanje derivata imidazopiridina

Info

Publication number
YU14392A
YU14392A YU14392A YU14392A YU14392A YU 14392 A YU14392 A YU 14392A YU 14392 A YU14392 A YU 14392A YU 14392 A YU14392 A YU 14392A YU 14392 A YU14392 A YU 14392A
Authority
YU
Yugoslavia
Prior art keywords
imidazopyridine derivatives
formula
obtaining
preparing mixtures
imidazopyridine
Prior art date
Application number
YU14392A
Other languages
English (en)
Other versions
YU48238B (sh
Inventor
D. Alker
R.J. Bass
K. Cooper
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of YU14392A publication Critical patent/YU14392A/sh
Publication of YU48238B publication Critical patent/YU48238B/sh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Prostheses (AREA)
  • Cosmetics (AREA)

Abstract

DERIVATI IMIDAZOPIRIDINA, POSTUPAK ZA DOBIJANJE SMEŠA SA NJIMA I POSTUPAK ZA DOBIJANJE DERIVATA IMIDAZOPIRIDINA, opisani su derivati imidazopiridina, jedinjenja formule; u kojoj X je CH ili N; Z je CH=CH ili S; A je CH2CH2, CH=CH, CH(OH)CH2, ili COCH2; B je direktna veza ili -CH2-, -CH(CH3)- ili -C(CH3)2-, ili kada Z je CH=CH, B može obrazovati kondenzovan ciklopentanov prsten vezan na benzenov prsten; Y kompletira kondenzovan benzo ili tienil prsten koji je po potrebi supstituisan sa halo ili C1-C4 alkil; n je 0, 1 ili 2; i m je 0 ili 1. Takodje je opisan postupak za dobijanje ovih derivata imidazopiridina koji obuhvata reakciju derivata piperidina formule (II) sa kiselinom formule (III) ili njenim aktiviranim derivatom: gde su X, Y, Z, A, B, n kao što je prethodno definisano.
YU14392A 1991-02-13 1992-02-12 Derivti imidazopiridina, postupak za dobijanje smeša sa njima i postupak za dobijanje derivata imidazopiridina YU48238B (sh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919102997A GB9102997D0 (en) 1991-02-13 1991-02-13 Therapeutic agents

Publications (2)

Publication Number Publication Date
YU14392A true YU14392A (sh) 1994-11-15
YU48238B YU48238B (sh) 1997-08-22

Family

ID=10689943

Family Applications (1)

Application Number Title Priority Date Filing Date
YU14392A YU48238B (sh) 1991-02-13 1992-02-12 Derivti imidazopiridina, postupak za dobijanje smeša sa njima i postupak za dobijanje derivata imidazopiridina

Country Status (29)

Country Link
US (1) US5358953A (sh)
EP (1) EP0572425B1 (sh)
JP (1) JP2506541B2 (sh)
KR (1) KR970005302B1 (sh)
CN (1) CN1040326C (sh)
AT (1) ATE109482T1 (sh)
AU (1) AU650322B2 (sh)
BR (1) BR9205615A (sh)
CA (1) CA2099381C (sh)
CZ (1) CZ280504B6 (sh)
DE (1) DE69200304T2 (sh)
DK (1) DK0572425T3 (sh)
EG (1) EG20085A (sh)
ES (1) ES2059212T3 (sh)
FI (1) FI933531A7 (sh)
GB (1) GB9102997D0 (sh)
HU (2) HUT65947A (sh)
IE (1) IE65125B1 (sh)
IL (1) IL100887A (sh)
MX (1) MX9200589A (sh)
MY (1) MY108437A (sh)
NO (1) NO300592B1 (sh)
NZ (1) NZ241597A (sh)
PL (1) PL169304B1 (sh)
RU (1) RU2114845C1 (sh)
TW (1) TW227000B (sh)
WO (1) WO1992014734A1 (sh)
YU (1) YU48238B (sh)
ZA (1) ZA921005B (sh)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2042421B1 (es) * 1992-05-22 1994-08-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 8-cloro-11-*1-*(5-metil-3-piridil)metil*-4-piperidiliden*-6,11-dihidro-5h-benzo*5,6*ciclohepta*1,2-b*piridina.
WO1996005201A1 (en) * 1994-08-10 1996-02-22 British Biotech Pharmaceuticals Limited Imidazopyridine derivatives as dual histamine (h1) and platelet activating factor (paf) antagonists
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.
US5866588A (en) * 1995-04-05 1999-02-02 British Biotech Pharmaceuticals Ltd. Imidazopyridine derivatives
US5567711A (en) * 1995-04-19 1996-10-22 Abbott Laboratories Indole-3-carbonyl and indole-3-sulfonyl derivatives as platelet activating factor antagonists
GB9508748D0 (en) * 1995-04-28 1995-06-14 British Biotech Pharm Benzimidazole derivatives
SE9801526D0 (sv) * 1998-04-29 1998-04-29 Astra Ab New compounds
AU7931301A (en) 2000-08-04 2002-02-18 Dmi Biosciences Inc Method of using diketopiperazines and composition containing them
PL2537524T3 (pl) 2003-05-15 2017-01-31 Ampio Pharmaceuticals, Inc. Leczenie chorób mediowanych przez komórki T
US7687515B2 (en) * 2006-01-17 2010-03-30 N.V. Organon 6-phenyl-1H-imidazo[4,5-c]pyridine-4-carbonitrile derivatives
AU2008349239B2 (en) 2008-01-30 2012-12-06 Nippon Zoki Pharmaceutical Co., Ltd. Piperidine derivative
EP2300011A4 (en) 2008-05-27 2012-06-20 Dmi Life Sciences Inc THERAPEUTIC PROCESSES AND COMPOUNDS
EP2727919B1 (en) * 2011-06-28 2019-05-08 Fujian Mindong Rejuvenation Pharmaceutical Co., Ltd. Benzocycloheptanethiophene derivatives for anti-allergic reactions
EP2766029B1 (en) 2011-10-10 2020-03-25 Ampio Pharmaceuticals, Inc. Treatment of degenerative joint disease
AU2012323320B2 (en) 2011-10-10 2017-05-11 Ampio Pharmaceuticals, Inc. Implantable medical devices with increased immune tolerance, and methods for making and implanting
AU2012328605B9 (en) * 2011-10-28 2017-08-03 Ampio Pharmaceuticals, Inc. Treatment of rhinitis
WO2014145729A2 (en) 2013-03-15 2014-09-18 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
JP6723222B2 (ja) 2014-08-18 2020-07-15 アンピオ ファーマシューティカルズ,インコーポレイテッド 関節病態の治療
WO2016209969A1 (en) 2015-06-22 2016-12-29 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases
CN113880801A (zh) * 2020-07-03 2022-01-04 合肥医工医药股份有限公司 一类三环化合物、其制备方法及其医药用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL132137C (sh) * 1963-04-24
JPH03503889A (ja) * 1988-03-15 1991-08-29 ジー.ディー.サール アンド カンパニー PAF拮抗剤としての1H/3H‐[4‐(N,N‐ジシクロアルキル/分枝アルキルカルボキサミド)‐ベンジル]イミダゾ[4,5‐c]ピリジン類
JP2511550B2 (ja) * 1988-04-28 1996-06-26 シェリング・コーポレーション 融合多環式化合物、組成物、製造方法およびpaf拮抗、抗ヒスタミンおよび/または抗炎症剤としてのその使用
US5250681A (en) * 1988-06-02 1993-10-05 Ajinomoto Co., Inc. Piperidine derivatives and hypotensives containing the same
US5114919A (en) * 1990-02-26 1992-05-19 Merck & Co., Inc. Adjuncts in cancer chemotherapy
EP0533695B1 (en) * 1990-05-09 1994-10-05 Pfizer Inc. IMIDAZO (4,5-c) PYRIDINES WITH PAF ANTAGONIST ACTIVITY

Also Published As

Publication number Publication date
ES2059212T3 (es) 1994-11-01
CN1064275A (zh) 1992-09-09
CZ280504B6 (cs) 1996-02-14
KR970005302B1 (ko) 1997-04-15
BR9205615A (pt) 1994-05-17
FI933531A0 (fi) 1993-08-10
CS42592A3 (en) 1992-09-16
IE65125B1 (en) 1995-10-04
DK0572425T3 (da) 1994-09-12
HU9302327D0 (en) 1993-10-28
FI933531L (fi) 1993-08-10
EP0572425A1 (en) 1993-12-08
IL100887A (en) 1996-01-19
WO1992014734A1 (en) 1992-09-03
MX9200589A (es) 1992-10-01
HUT65947A (en) 1994-08-29
IE920449A1 (en) 1992-08-12
AU650322B2 (en) 1994-06-16
NO932889D0 (no) 1993-08-13
EG20085A (en) 1997-05-31
JP2506541B2 (ja) 1996-06-12
ZA921005B (en) 1993-08-12
MY108437A (en) 1996-09-30
PL169304B1 (pl) 1996-06-28
AU1168392A (en) 1992-09-15
US5358953A (en) 1994-10-25
TW227000B (sh) 1994-07-21
RU2114845C1 (ru) 1998-07-10
DE69200304T2 (de) 1994-12-08
NO932889L (no) 1993-08-13
CA2099381C (en) 1996-07-09
NO300592B1 (no) 1997-06-23
GB9102997D0 (en) 1991-03-27
HU211202A9 (en) 1995-11-28
DE69200304D1 (de) 1994-09-08
CA2099381A1 (en) 1992-08-14
ATE109482T1 (de) 1994-08-15
EP0572425B1 (en) 1994-08-03
IL100887A0 (en) 1992-11-15
JPH06504992A (ja) 1994-06-09
NZ241597A (en) 1993-04-28
CN1040326C (zh) 1998-10-21
YU48238B (sh) 1997-08-22
FI933531A7 (fi) 1993-08-10

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