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YU126186A - Process for making water gelating solutions of arylpropionic acid derivatives, which can be respirated through skin - Google Patents

Process for making water gelating solutions of arylpropionic acid derivatives, which can be respirated through skin

Info

Publication number
YU126186A
YU126186A YU01261/86A YU126186A YU126186A YU 126186 A YU126186 A YU 126186A YU 01261/86 A YU01261/86 A YU 01261/86A YU 126186 A YU126186 A YU 126186A YU 126186 A YU126186 A YU 126186A
Authority
YU
Yugoslavia
Prior art keywords
weight
acid derivatives
respirated
skin
solutions
Prior art date
Application number
YU01261/86A
Other versions
YU46012B (en
Inventor
M Loehner
H H Wagener
Original Assignee
Dolorgiet Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dolorgiet Gmbh filed Critical Dolorgiet Gmbh
Publication of YU126186A publication Critical patent/YU126186A/en
Publication of YU46012B publication Critical patent/YU46012B/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)

Abstract

Transdermally absorbable water-containing preparations of therapeutically active arylpropionic acid derivatives comprises 1 to 15% by weight of such active ingredient, from 10 to 40% by weight of polyoxyethylene polyoxypropylene copolymers, from 10 to 50% by weight of one or more physiologically acceptable organic solvents, optionally up to 1% by weight of preservatives, colorants and/or perfumes, and at least 10% by weight of water. From polyoxyethylene polyoxypropylene copolymers having a relative molecular weight of more than 6,000 there may also be prepared gels, if certain ratios of amounts are chosen.
YU126186A 1985-09-12 1986-07-16 PROCEDURE FOR PREPARATION OF AQUEOUS GELING SOLUTIONS OF ARYLPROPIONIC ACID DERIVATIVES WHICH CAN BE RESPONSIBLE THROUGH THE SKIN YU46012B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853532562 DE3532562A1 (en) 1985-09-12 1985-09-12 TRANSDERMALLY RESORBABLE, WATER-BASED PREPARATIONS OF ARYLPROPIONIC ACID DERIVATIVES AND METHOD FOR THE PRODUCTION THEREOF

Publications (2)

Publication Number Publication Date
YU126186A true YU126186A (en) 1989-10-31
YU46012B YU46012B (en) 1992-12-21

Family

ID=6280783

Family Applications (1)

Application Number Title Priority Date Filing Date
YU126186A YU46012B (en) 1985-09-12 1986-07-16 PROCEDURE FOR PREPARATION OF AQUEOUS GELING SOLUTIONS OF ARYLPROPIONIC ACID DERIVATIVES WHICH CAN BE RESPONSIBLE THROUGH THE SKIN

Country Status (10)

Country Link
US (1) US4849418A (en)
EP (1) EP0215423B1 (en)
JP (1) JPH078786B2 (en)
AT (1) ATE63220T1 (en)
CA (1) CA1269328A (en)
DE (2) DE3532562A1 (en)
ES (1) ES2002140A6 (en)
NO (1) NO172028C (en)
YU (1) YU46012B (en)
ZA (1) ZA866917B (en)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8701392D0 (en) * 1987-01-22 1987-02-25 Boots Co Plc Therapeutic agents
US5104656A (en) * 1989-06-16 1992-04-14 Seth Pyare L Percutaneous treatment with a high potency non-steroidal anti-inflammatory agent
US5093133A (en) * 1990-01-24 1992-03-03 Mcneil-Ppc, Inc. Method for percutaneous delivery of ibuprofen using hydroalcoholic gel
IT1243342B (en) * 1990-07-13 1994-06-10 Farcon Ag ORAL PHARMACEUTICAL COMPOSITIONS FOR LIQUID ANTI-INFLAMMATORY ACTIVITIES
US5210099A (en) * 1991-02-11 1993-05-11 American Home Products Corporation Analgesic compositions
US5308621A (en) * 1991-02-18 1994-05-03 Commonwealth Scientific And Industrial Research Organisation Ascorbic acid composition and transdermal administration method
DE4140183C2 (en) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retard form for a medicine containing flurbiprofen
DE4140185C2 (en) * 1991-12-05 1996-02-01 Alfatec Pharma Gmbh Medicament containing a 2-arylpropionic acid derivative in nanosol form and its preparation
DE4140172C2 (en) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Retard form for a drug containing ibuprofen
DE4140184C2 (en) * 1991-12-05 1995-12-21 Alfatec Pharma Gmbh Acute form for a medicine containing flurbiprofen
ATE137959T1 (en) * 1992-02-12 1996-06-15 Janssen Cilag S P A LIPOSOMAL PIROXYCAM FORMULATION
EP0625898B1 (en) * 1992-02-12 1996-05-15 JANSSEN-CILAG S.p.A. Liposomal piroxicam formulations
JPH07503953A (en) * 1992-02-12 1995-04-27 ジヤンセン・シラグ・ソチエタ・ペル・アチオニ Liposomal itraconazole composition
CN1106259A (en) * 1994-02-05 1995-08-09 日东制药株式会社 Antiphlogistic and analgesic gel agent for external use containing propanoic acid non steroid pharmaceutical as effective composition
JP3782834B2 (en) * 1994-10-26 2006-06-07 株式会社トクホン Analgesic anti-inflammatory patch
US5702720A (en) * 1995-12-22 1997-12-30 Minnesota Mining And Manufacturing Company Transdermal device for the delivery of flurbiprofen
NZ511708A (en) 1998-12-01 2003-12-19 Univ Kentucky Res Found A method for enhancing protective cellular responses to genotoxic stress in skin
AU770516B2 (en) * 1999-09-11 2004-02-26 Procter & Gamble Company, The Polyoxyalkylene copolymers containing pourable liquid vehicles
DE10001096A1 (en) * 2000-01-13 2001-07-26 Lohmann Therapie Syst Lts Transdermal therapeutic system for prolonged release of drugs, e.g. steroid hormones, including reservoir providing slow release of perfume to improve patient compliance
US7138133B2 (en) * 2001-10-10 2006-11-21 The Procter & Gamble Company Orally administered liquid compositions
ES2379464T3 (en) * 2002-06-17 2012-04-26 Taro Pharmaceuticals U.S.A., Inc. Ibuprofen suspension
DE102005019628A1 (en) * 2005-04-26 2006-11-09 Technische Universität Braunschweig Formulation for dermal application
DE102005033543A1 (en) * 2005-07-14 2007-01-18 Grünenthal GmbH A fragrance-containing transdermal therapeutic system
US20080317684A1 (en) * 2006-09-06 2008-12-25 Isw Group, Inc. Topical Compositions
ES2343208T3 (en) * 2007-04-19 2010-07-26 DR. AUGUST WOLFF GMBH & CO. KG ARZNEIMITTEL GEL FOR WOUND TREATMENT.
GB0921686D0 (en) * 2009-12-11 2010-01-27 Reckitt Benckiser Healthcare I Topical formulation
BR112013028435A2 (en) 2011-05-03 2017-01-24 Aponia Lab Inc composition for transdermal application
NZ606177A (en) * 2012-01-30 2014-03-28 Dolorgiet Gmbh & Co Kg Compositions for the treatment of actinic keratosis
EP3213744A1 (en) * 2016-03-01 2017-09-06 Chemische Fabrik Kreussler & Co. Gmbh Galenical formulation of nsaids

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3740421A (en) * 1966-09-19 1973-06-19 Basf Wyandotte Corp Polyoxyethylene-polyoxypropylene aqueous gels
DE1617480B2 (en) * 1967-08-01 1973-02-01 Farbwerke Hoechst AG, vormals Mei ster Lucius & Brunmg, 6000 Frankfurt GEL BASES
US4100271A (en) * 1976-02-26 1978-07-11 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
JPS5829706A (en) * 1981-08-14 1983-02-22 Toko Yakuhin Kogyo Kk Antiphlogistic and analgesic agent for external use
DE3205504C2 (en) * 1982-02-16 1983-12-01 Dolorgiet Gmbh & Co Kg, 5300 Bonn Topical drug containing ibuprofen
JPS59222409A (en) * 1983-06-01 1984-12-14 Nippon Redarii Kk Anti-inflammatory and analgesic gel ointment
US4511563A (en) * 1983-07-15 1985-04-16 Basf Wyandotte Corporation Clear analgesic gels with reduced tackiness
JPS60209515A (en) * 1984-04-03 1985-10-22 Hokuriku Seiyaku Co Ltd Anti-inflammatory and analgesic cream agent
DE3437599C2 (en) * 1984-10-13 1987-04-16 Dolorgiet GmbH & Co KG, 5205 St Augustin Soft gelatin capsules containing ibuprofen

Also Published As

Publication number Publication date
EP0215423A2 (en) 1987-03-25
NO863636L (en) 1987-03-13
EP0215423A3 (en) 1988-03-23
EP0215423B1 (en) 1991-05-08
DE3679128D1 (en) 1991-06-13
NO172028B (en) 1993-02-22
YU46012B (en) 1992-12-21
NO863636D0 (en) 1986-09-11
US4849418A (en) 1989-07-18
JPH078786B2 (en) 1995-02-01
ATE63220T1 (en) 1991-05-15
ES2002140A6 (en) 1988-07-16
DE3532562A1 (en) 1987-03-12
NO172028C (en) 1993-06-02
CA1269328A (en) 1990-05-22
JPS6261917A (en) 1987-03-18
ZA866917B (en) 1987-05-27

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