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WO2025221089A1 - Spinal fusion implant - Google Patents

Spinal fusion implant

Info

Publication number
WO2025221089A1
WO2025221089A1 PCT/KR2025/095065 KR2025095065W WO2025221089A1 WO 2025221089 A1 WO2025221089 A1 WO 2025221089A1 KR 2025095065 W KR2025095065 W KR 2025095065W WO 2025221089 A1 WO2025221089 A1 WO 2025221089A1
Authority
WO
WIPO (PCT)
Prior art keywords
frame
contact portion
spinal fusion
implant
vertebrae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/KR2025/095065
Other languages
French (fr)
Korean (ko)
Inventor
조명래
정연규
손동민
정의수
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cgbio Co ltd
Original Assignee
Cgbio Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020240187430A external-priority patent/KR20250153088A/en
Application filed by Cgbio Co ltd filed Critical Cgbio Co ltd
Publication of WO2025221089A1 publication Critical patent/WO2025221089A1/en
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/46—Special tools for implanting artificial joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36—Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/58—Materials at least partially resorbable by the body

Definitions

  • the present invention relates to an implant for spinal fusion, and more particularly, to an implant for spinal fusion that is inserted between adjacent vertebrae to promote bone growth.
  • the intervertebral disc is a disc-shaped cartilaginous structure that connects the vertebrae to the vertebrae, protecting the vertebrae and absorbing shock.
  • the intervertebral disc is largely composed of the annulus fibrosus and the nucleus pulposus.
  • the annulus fibrosus is the central portion of the disc and is composed of a jelly-like substance that absorbs shock and allows the spine to move flexibly.
  • the annulus fibrosus is the outer, tough fibrous structure that surrounds the nucleus pulposus and supports the disc, allowing it to remain in place between the vertebrae.
  • spinal fusion which involves removing the damaged disc and replacing it with an artificial structure called a spinal implant between two adjacent vertebrae.
  • bone grafting materials bone grafting materials, bone morphogenetic proteins, peptides, etc. (hereinafter referred to as "bone grafting materials") filled inside the spinal fusion implant may leak out due to the saline solution. This may impede bone growth and reduce the therapeutic effect.
  • an improved spinal fusion implant is required that can maintain the bone graft material filled inside the spinal fusion implant without leaking out and promote bone growth.
  • the present invention has been devised to solve the above problems, and its purpose is to provide a spinal fusion implant that can maintain a preserved state without bone graft material leaking out of the inside of the spinal fusion implant and promote bone growth.
  • an implant for spinal fusion comprising: a frame structure disposed between adjacent vertebrae, forming a truss structure and supporting the vertebrae; and a porous structure filling at least a portion of the internal space of the frame structure and coming into contact with the adjacent vertebrae.
  • the frame structure may include an upper frame; a lower frame disposed spaced apart from the upper frame; and a web frame disposed between the upper frame and the lower frame and having a node formed therein.
  • a protruding portion may be formed on the upper surface of the upper frame and the lower surface of the lower frame to contact the adjacent vertebrae, respectively.
  • the frame structure is inserted and placed between the vertebrae from one end, and the upper frame and the lower frame can form an insertion direction and an inclination of the frame structure such that the gap between one end of the upper frame and the lower frame is greater than the gap between the other ends.
  • the frame structure may further include a front frame that connects one end of the upper frame and one end of the lower frame, and is formed to be curved and protrude in a direction inserted between the vertebrae; and a rear frame that connects the other end of the upper frame and the other end of the lower frame, and has a connecting portion formed that is detachable from a surgical instrument.
  • the frame structure may further include an upper reinforcing frame connecting the upper frame; and a lower reinforcing frame connecting the lower frame.
  • the porous structure includes struts that are connected to each other with a predetermined length and thickness to form a gap, and the average thickness of the frame structure may be thicker than the average thickness of the struts.
  • the present invention may include a frame structure disposed between adjacent vertebrae to support the vertebrae; and a porous structure filling at least a portion of an internal space of the frame structure and confining a bone graft material injected into the internal space.
  • the porous structure can form a plurality of pores by including struts that are connected to each other with a predetermined length and thickness.
  • the porous structure is divided into an upper contact portion disposed on the upper part of the frame structure, a lower contact portion disposed on the lower part of the frame structure, and a central connecting portion extending from the upper contact portion and the lower contact portion, and the average size of the pores of the central connecting portion may be smaller than the average sizes of the pores of the upper contact portion and the lower contact portion.
  • the average size of the gaps of the upper contact portion, the lower contact portion, and the central connecting portion may be in the range of 0.1 mm to 1.5 mm.
  • the porosity of the upper contact portion, the lower contact portion, and the central connecting portion is in the range of 50% to 90%, and the central connecting portion may have a greater porosity than the upper contact portion and the lower contact portion.
  • an injection hole into which the bone graft material is injected may be formed in at least one of the upper contact portion, the lower contact portion, and the central connecting portion.
  • At least a portion of the upper surface of the frame structure may protrude upwardly from the upper contact portion, and at least a portion of the lower surface of the frame structure may protrude downwardly from the lower contact portion.
  • the surfaces of the upper contact portion and the lower contact portion may be formed to have a rougher surface than the surface of the central connecting portion.
  • the present invention can be inserted between adjacent vertebrae to fuse the vertebrae.
  • the present invention can promote bone growth so that fusion between spinal bones can occur within a short period of time by preventing bone graft material from leaking out due to saline solution.
  • the present invention can stably support the spinal bone while facilitating the fusion of surrounding bone tissue.
  • the present invention can form an injection hole at a location where a bone graft material can be easily injected depending on the structure of the spinal bone and surgical conditions.
  • the present invention can prevent the porous structure from being damaged by movement of the vertebrae or load transmitted from the vertebrae as the frame structure supports the vertebrae.
  • the present invention can promote bone growth of the spinal bone by forming the contact surface of the porous structure in contact with the spinal bone rough.
  • the present invention can be firmly fixed without moving while inserted between the vertebrae.
  • the present invention can enable the spine to form natural lordotic and kyphotic angles.
  • the present invention can be easily inserted between adjacent vertebrae.
  • the present invention since the present invention has a structure in which strength is reinforced, it can stably support even a large load transmitted to the spinal bone.
  • Figure 1 is a perspective view illustrating an implant for spinal fusion according to one embodiment of the present invention
  • Figure 2 is a drawing showing a porous structure arranged inside the frame structure of Figure 1;
  • Figure 3 is a side view of Figure 1;
  • Figure 4 is a drawing showing the structure of the web frame of Figure 3.
  • Figure 5 is a drawing showing a state in which the spinal fusion implant of Figure 1 is inserted between the vertebrae.
  • Figure 6 is a bottom view of Figure 1;
  • Figure 7 is a drawing showing the strut and the gap by enlarging area A of Figure 1.
  • Fig. 8 is a cross-sectional view taken along the cutting line VIII-VIII of Fig. 2;
  • Fig. 9 is an enlarged view of a portion of the upper contact portion or the lower contact portion
  • Figure 10 is an enlarged view of a portion of the central connecting part.
  • Figure 11 is a drawing showing an implant for spinal fusion in which an injection hole is formed in the upper contact portion among various embodiments of the present invention.
  • Figure 12 is a drawing showing an implant for spinal fusion in which a plurality of injection holes are formed and a lower reinforcing frame is formed in a flat shape among various embodiments of the present invention.
  • FIG. 13 is a drawing showing an implant for spinal fusion in which the rear frame of the frame structure is formed to protrude and be curved among various embodiments of the present invention and an injection hole is formed in the central connecting portion.
  • FIG. 14 is a drawing showing an implant for spinal fusion in which the rear frame of the frame structure is formed to protrude and be curved and a plurality of injection holes are formed among various embodiments of the present invention.
  • Figure 15 is a drawing showing a state in which the spinal fusion implant of the present invention is positioned in a way that it is tilted toward the front of the spinal bone.
  • Figure 16 is a drawing showing a state in which the spinal fusion implant of the present invention is placed diagonally between the vertebrae.
  • Figure 17 is a drawing showing a state in which multiple implants for spinal fusion of the present invention are placed between vertebrae.
  • forward is the direction parallel to the positive x-axis
  • backward is the direction parallel to the negative x-axis
  • Up is the direction parallel to the positive y-axis
  • down is the direction parallel to the negative y-axis.
  • the vertebra located above the neighboring vertebrae is referred to as the upper vertebrae, and the vertebra located below is referred to as the lower vertebrae.
  • FIG. 1 is a perspective view illustrating an implant for spinal fusion according to one embodiment of the present invention
  • FIG. 2 is a drawing illustrating a porous structure arranged inside the frame structure of FIG. 1.
  • an implant (10) for spinal fusion is inserted between adjacent vertebrae to promote bone growth, and includes a frame structure (100) and a porous structure (200).
  • Figure 3 is a side view of Figure 1.
  • a frame structure (100) is inserted between adjacent vertebrae to support the vertebrae, and can form a truss structure to support the load transferred to the vertebrae.
  • the frame structure (100) is preferably made of a metal powder or polymer powder that can support the load and has biocompatibility. Accordingly, the frame structure (100) can be made of titanium, a titanium alloy, a cobalt-chromium alloy, tantalum, magnesium, or the like.
  • the frame structure (100) may include an upper frame (110), a lower frame (120), a web frame (130), a front frame (140), a rear frame (150), an upper reinforcing frame (161), and a lower reinforcing frame (162).
  • the upper frame (110) supports the upper spine and may be formed to have a predetermined length and thickness.
  • a plurality of upper frames (110) may be provided, and for example, they may be formed as a pair spaced apart from each other and parallel to each other.
  • an upper reinforcing frame (161) By placing an upper reinforcing frame (161) between a plurality of upper frames (110), for example, a pair of upper frames (110), the connection between the upper frames (110) can be strengthened and the supporting force can be reinforced.
  • At least a portion of the upper frame (110) may be formed to protrude upward from the upper contact portion (230, see FIG. 8) of the porous structure (200) described later. By forming at least a portion of the upper frame (110) to protrude, damage to the porous structure (200) due to a load transmitted to the upper spinal bone can be prevented.
  • a protruding portion (111) may be formed on the upper surface of the upper frame (110).
  • the protruding portion (111) comes into contact with the upper vertebrae and may allow the spinal fusion implant (10) of the present invention to be fixed in position while inserted between the upper and lower vertebrae.
  • the uneven portion (111) can be formed in the shape of a screw thread with a flat end, a wave shape with a flat top surface, etc.
  • the flat portion of the uneven portion (111) can minimize damage to the upper vertebrae and support the upper vertebrae.
  • the lower frame (120) supports the lower spine and may be formed to have a predetermined length and thickness.
  • a plurality of lower frames (120) may be provided, and for example, they may be formed as a pair spaced apart and parallel to each other.
  • the lower frames (120) may be arranged to correspond to the upper frame (110).
  • a lower reinforcing frame (162) By placing a lower reinforcing frame (162) between a plurality of lower frames (120), for example, a pair of lower frames (120), the connection between the lower frames (120) can be strengthened and the supporting force can be reinforced.
  • At least a portion of the lower frame (120) may be formed to protrude downward from the lower contact portion (240, see FIG. 8) of the porous structure (200) described below. By forming at least a portion of the lower frame (120) to protrude, damage to the porous structure (200) due to a load transmitted to the lower vertebrae can be prevented.
  • a protruding portion (121) may be formed on the lower surface of the lower frame (120).
  • the protruding portion (121) comes into contact with the lower vertebrae, and can fix the position of the spinal fusion implant (10) of the present invention while it is inserted between the upper and lower vertebrae.
  • the uneven portion (121) can be formed in the shape of a screw thread with a flat end, a wave shape with a flat top surface, etc.
  • the flat portion of the uneven portion (121) can minimize damage to the lower vertebrae and support the lower vertebrae.
  • Figure 4 is a drawing illustrating the structure of the web frame of Figure 3.
  • a web frame (130) may be positioned between an upper frame (110) and a lower frame (120) and may form a truss structure supporting the upper frame (110) and the lower frame (120).
  • a plurality of web frames (130) may be connected to each other and may form a truss structure having an approximately triangular shape.
  • the web frames (130) may include nodes (131) formed by connections between each other and/or between the upper frame (110) and the lower frame (120).
  • the truss structure of the web frame (130) can stably support the spinal column by evenly distributing the load transferred from the upper frame (110) and the lower frame (120). Since the frame structure (100) including the web frame (130) supports the load transferred to the spinal column, the porous structure (200) can be prevented from being damaged by the load.
  • the web frame (130) can form at least one truss structure depending on the length of the upper frame (110) and the lower frame (120).
  • An injection hole (260), which will be described later, can be formed between the web frames (130). The injection hole (260) will be described later.
  • Figure 5 is a drawing showing the spinal fusion implant of Figure 1 inserted between the vertebrae.
  • the upper frame (110) and the lower frame (120) of the frame structure (100) can form an insertion direction and an incline.
  • the insertion direction is a direction in which one end of the upper frame (110) and one end of the lower frame (120) face forward and are inserted between the vertebrae.
  • one end of the upper frame (110) may refer to the position of the front end of the uneven portion (111) positioned at the frontmost part of the upper frame (110), or may refer to a portion connected to the front frame (140).
  • One end of the lower frame (120) may refer to the position of the front end of the uneven portion (121) positioned at the frontmost part of the lower frame (120), or may refer to a portion connected to the front frame (140).
  • the other end of the upper frame (110) may refer to the position of the rear end of the uneven portion (111) positioned at the rearmost end of the upper frame (110), or may refer to a portion connected to the rear frame (150).
  • the other end of the lower frame (120) may refer to the position of the rear end of the uneven portion (121) positioned at the rearmost end of the lower frame (120), or may refer to a portion connected to the rear frame (150).
  • one end of the upper frame (110) and one end of the lower frame (120) may be the first parts to enter between the vertebrae among the upper frame (110) and the lower frame (120).
  • the other end of the upper frame (110) and the other end of the lower frame (120) may be the last parts to enter between the vertebrae among the upper frame (110) and the lower frame (120).
  • the gap between one end of the upper frame (110) and one end of the lower frame (120) may be greater than the gap between the other end of the upper frame (110) and the other end of the lower frame (120). That is, the upper frame (110) and the lower frame (120) are arranged to form an insertion direction and an incline, thereby allowing the spinal bones to form natural lordotic and kyphotic angles.
  • the spinal bone into which the spinal fusion implant (10) of the present invention is inserted can naturally bend into an S shape like a normal spinal bone before surgery.
  • the upper frame (110) and the lower frame (120) include soft curved surfaces corresponding to the shape of the spinal bone they contact, so that the spinal bone can bend more naturally after surgery.
  • the front frame (140) is configured to connect one end of the upper frame (110) and one end of the lower frame (120) to facilitate insertion between the vertebrae and may be formed to protrude in the insertion direction.
  • the front frame (140) protrudes forward and is formed to be curved, so that the frame structure (100) can have a shape close to a streamlined shape overall.
  • the rear frame (150) supports the upper frame (110) and the lower frame (120) together with the web frame (130), and can connect the other end of the upper frame (110) and the other end of the lower frame (120).
  • the rear frame (150) may be formed with a connecting portion (151, see Fig. 6) that is detachable from a surgical instrument.
  • the surgical instrument refers to a mechanism that pushes the spinal fusion implant (10) of the present invention so that it can advance in the insertion direction.
  • the connecting part (151) can be connected to the surgical instrument in various ways, such as a bolting connection method (see Fig. 8), a pin connection method, a fitting method, or a magnetic connection method.
  • an upper reinforcing frame (161) may be placed between a pair of upper frames (110) to reinforce the connection between the upper frames (110) and at the same time reinforce the supporting force of the upper frames (110).
  • the upper reinforcing frame (161) may be formed so as not to protrude further than the uneven portion (111) of the upper frame (110) described above.
  • the upper reinforcing frame (161) may be arranged perpendicular to or diagonally relative to the upper frame (110). To reinforce the supporting force, it is preferable that the upper reinforcing frames (161) be arranged in multiple pieces.
  • Figure 6 is a bottom view of Figure 1.
  • the lower reinforcing frame (162) may be placed between a pair of lower frames (120) to reinforce the connection between the lower frames (120) and at the same time reinforce the supporting force of the lower frames (120).
  • the lower reinforcing frame (162) may be formed so as not to protrude further than the uneven portion (121) of the lower frame (120) described above.
  • the lower reinforcing frame (162) may be arranged perpendicular to or diagonally relative to the lower frame (120). To reinforce the supporting force, it is preferable that the lower reinforcing frames (162) be arranged in multiple pieces.
  • the frame structure (100) may be formed to have an average thickness that is thicker than the average thickness of the struts (210) of the porous structure (200) described later. It is preferable that the frame structure (100) be formed to have a thickness that is thicker than the struts (210) of the porous structure (200) in order to support the load transmitted to the spinal bone.
  • the strut (210) can be formed to surround the upper reinforcing frame (161) and the lower reinforcing frame (162). Since the strut (210) is formed to surround the upper reinforcing frame (161) and the lower reinforcing frame (162), the capacity of the frame structure (100) to accommodate the porous structure (200) can be strengthened.
  • the porous structure (200) can be formed by filling a portion of the internal space of the frame structure (100) to confine the bone graft material injected into the internal space of the frame structure (100) and promote bone growth.
  • the porous structure (200) can contact the vertebrae without supporting the load transmitted from the vertebrae and promote bone growth of the vertebrae.
  • the porous structure (200) can be formed by laminating using a 3D printing method and having a rough surface. By having the rough surface of the porous structure (200) come into contact with the spinal bone, bone growth can be promoted.
  • Figure 7 is a drawing showing the strut and the gap by enlarging area A of Figure 1.
  • the porous structure (200) may include struts (210) formed with a predetermined length and thickness.
  • the struts (210) may be connected to each other to form a plurality of voids (220).
  • One end and the other end of a strut (210) may be connected to one end or the other end of another strut (210).
  • Fig. 8 is a cross-sectional view taken along the cutting line VIII-VIII of Fig. 2.
  • the porous structure (200) can be divided into an upper contact portion (230), a lower contact portion (240), and a central connection portion (250).
  • the upper contact portion (230) is placed on the upper portion of the frame structure (100) and is a portion that comes into contact with the upper spinal bone, and is a predetermined area having a predetermined thickness.
  • the lower contact portion (240) is placed at the lower portion of the frame structure (100) and is a portion that comes into contact with the lower spine, and is a predetermined area having a predetermined thickness.
  • the central connecting portion (250) is positioned between the upper contact portion (230) and the lower contact portion (240), and is a portion extending from the upper contact portion (230) and the lower contact portion (240), and is the remaining area excluding the upper contact portion (230) and the lower contact portion (240).
  • the upper contact portion (230) and the lower contact portion (240) come into contact with the spinal bone and can promote bone growth. Therefore, the upper contact portion (230) and the lower contact portion (240) can be formed to have a rougher surface than the surface of the central connecting portion (250).
  • the upper contact portion (230) and the lower contact portion (240) may be formed to have an elastic modulus that matches the elastic modulus of the inserted vertebra.
  • the upper contact portion (230) and the lower contact portion (240) may be formed to have an elastic modulus within a range of 0.1 GPa to 10 GPa, which is the same as or close to the elastic modulus of the vertebra, in order to prevent bone subsidence.
  • the bone subsidence phenomenon is a phenomenon in which the gap between the vertebrae decreases as the spinal fusion implant (10) descends into the vertebrae.
  • Fig. 9 is an enlarged view of a portion of the upper contact portion or the lower contact portion
  • Fig. 10 is an enlarged view of a portion of the central connecting portion.
  • the central connecting portion (250) is formed so that the average size of the gap (220) is smaller than the average sizes of the gaps (220) of the upper contact portion (230) and the lower contact portion (240), and the average size of the gap (220) may be in the range of 0.1 mm to 1.5 mm.
  • the porosity of the upper contact portion (230), the lower contact portion (240), and the central connection portion (250) is preferably 50% to 90%, and the central connection portion (250) preferably has a greater porosity than the upper contact portion (230) and the lower contact portion (240). Accordingly, the effect of preventing the outflow of the bone graft material and the effect of infiltrating the bone tissue can be further improved.
  • a gap (220) can be formed with a gradually changing size. That is, the size of the gap (220) can gradually become smaller as it goes from the upper contact portion (230) and the lower contact portion (240) to the central connection portion (250).
  • an injection hole (260) into which a bone graft material is injected may be formed in at least one of the upper contact portion (230), the lower contact portion (240), and the central connection portion (250).
  • the injection holes (260) may be formed in multiples or in singles, with different sizes and locations depending on the structure of the spinal bone and surgical conditions. The fewer the number of injection holes (260), the lower the likelihood of bone graft material leakage. While FIGS. 1 and 2 illustrate that the injection holes (260) are formed on one side of the central connecting portion (250), the present invention is not limited thereto.
  • FIG. 11 is a drawing illustrating a spinal fusion implant having an injection hole formed in an upper contact portion among various embodiments of the present invention
  • FIG. 12 is a drawing illustrating a spinal fusion implant having a plurality of injection holes formed and a lower reinforcing frame formed in a flat shape among various embodiments of the present invention
  • FIG. 13 is a drawing illustrating a spinal fusion implant having a rear frame of a frame structure formed to protrude and be curved and an injection hole formed in a central connecting portion among various embodiments of the present invention
  • FIG. 14 is a drawing illustrating a spinal fusion implant having a rear frame of a frame structure formed to protrude and be curved and a plurality of injection holes formed among various embodiments of the present invention.
  • the present invention includes a frame structure (100) formed in a shape conforming to the shape of a spinal bone and a porous structure (200) including a central connecting portion (250) having a relatively small gap (220), and can be implemented in various forms.
  • the present invention can be implemented as an implant (10) for spinal fusion in which an injection hole (260) is formed to have a predetermined depth downward from an upper contact portion (230).
  • the present invention can be implemented as a spinal fusion implant (10) in which multiple injection holes (260) are formed in the upper contact portion (230) and the central connecting portion (250).
  • the lower reinforcing frame (162) may be in the form of a flat plate rather than a bar.
  • the present invention can be implemented as a spinal fusion implant (10) in which the rear frame (150) of the frame structure (100) is formed to protrude and be curved, and an injection hole (260) is formed in the central connecting portion (250).
  • the lower reinforcing frame (162) may be in the form of a plate rather than a bar.
  • the present invention can be implemented as a spinal fusion implant (10) in which the rear frame (150) of the frame structure (100) is formed to protrude and curve and a plurality of injection holes (260) are formed.
  • the injection holes (260) can be formed in the upper contact portion (230) and the central connecting portion (250).
  • the lower reinforcing frame (162) can be in the form of a plate rather than a bar.
  • FIG. 15 is a drawing showing a state in which the spinal fusion implant of the present invention is positioned in a forward direction of the spinal bones
  • FIG. 16 is a drawing showing a state in which the spinal fusion implant of the present invention is positioned diagonally between the spinal bones
  • FIG. 17 is a drawing showing a state in which the spinal fusion implant of the present invention is positioned in multiple numbers between the spinal bones.
  • the present invention can be inserted and placed in various forms depending on the structure of the spinal bone and surgical conditions.
  • the present invention is arranged to be biased toward the front side of the vertebrae and can support the neighboring vertebrae.
  • the present invention is arranged diagonally with respect to the insertion direction and can support neighboring vertebrae.
  • the present invention is symmetrically arranged in a plurality of vertebrae, each of which can share the load and support the neighboring vertebrae.
  • the spinal fusion implant (10) can be inserted between adjacent vertebrae to fuse the vertebrae.
  • the present invention can promote bone growth so that fusion between the vertebrae can occur quickly by preventing the bone graft material from leaking out due to saline solution.
  • the present invention can facilitate fusion of surrounding bone tissues while stably supporting the vertebrae.
  • the present invention can form an injection hole (260) at a location where the bone graft material can be easily injected depending on the structure of the vertebrae and surgical conditions.
  • the present invention can prevent the porous structure (200) from being damaged by movement of the vertebrae or a load transmitted from the vertebrae as the frame structure (100) supports the vertebrae.
  • the present invention can promote bone growth of the vertebrae by forming a rough contact surface of the porous structure (200) that comes into contact with the vertebrae.
  • the present invention can be firmly fixed without moving when inserted between vertebrae.
  • the present invention can enable the spine to form natural lordotic and kyphotic angles.
  • the present invention can be easily inserted between adjacent vertebrae.
  • the present invention can stably support even large loads transmitted to the vertebrae due to its reinforced structure.

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Abstract

The present invention relates to a spinal fusion implant and, more specifically, to a spinal fusion implant, which is inserted between neighboring vertebrae so as to promote bone growth. Provided in one embodiment of the present invention is the spinal fusion implant comprising: a frame structure, which is disposed between the neighboring vertebrae, forms a truss structure, and supports the vertebrae; and a porous structure which fills at least a portion of the inner space of the frame structure, and which comes into contact with the neighboring vertebrae. The present invention can include: the frame structure disposed between the neighboring vertebrae so as to support the vertebrae; and the porous structure which fills at least a portion of the inner space of the frame structure, and which confines a bone graft material injected into the inner space.

Description

척추 유합용 임플란트Implants for spinal fusion

본 발명은 척추 유합용 임플란트에 관한 것으로서, 더욱 상세하게는 이웃하는 척추 뼈 사이에 삽입되어 골 성장을 촉진하는 척추 유합용 임플란트에 관한 것이다.The present invention relates to an implant for spinal fusion, and more particularly, to an implant for spinal fusion that is inserted between adjacent vertebrae to promote bone growth.

본 명세서에 달리 표시되지 않는 한, 이 식별항목에 설명되는 내용들은 이 출원의 청구항들에 대한 종래기술이 아니며, 이 식별항목에 기재된다고 하여 종래기술이라고 인정되는 것은 아니다.Unless otherwise indicated herein, the matters described in this identifier are not prior art to the claims of this application, and their description in this identifier is not intended to be deemed prior art.

추간판은 척추 뼈와 척추 뼈를 연결하는 원반 형태의 연골 구조물로, 척추 뼈를 보호하고 충격을 흡수하는 역할을 한다.The intervertebral disc is a disc-shaped cartilaginous structure that connects the vertebrae to the vertebrae, protecting the vertebrae and absorbing shock.

추간판은 크게 섬유륜과 수핵으로 구성된다. 섬유륜은 추간판의 중심 부분으로 젤리 같은 물질로 이루어져 있어 충격을 흡수하고 척추가 유연하게 움직일 수 있도록 하고, 섬유륜은 수핵을 감싸는 외부의 단단한 섬유질 구조로, 추간판이 척추 뼈 사이에서 제자리를 유지할 수 있도록 지지한다.The intervertebral disc is largely composed of the annulus fibrosus and the nucleus pulposus. The annulus fibrosus is the central portion of the disc and is composed of a jelly-like substance that absorbs shock and allows the spine to move flexibly. The annulus fibrosus is the outer, tough fibrous structure that surrounds the nucleus pulposus and supports the disc, allowing it to remain in place between the vertebrae.

그런데, 노화, 과도한 움직임, 잘못된 자세 등으로 추간판이 손상되면, 추간판 탈출증이나 퇴행성 추간판 질환과 같은 신경 증상이 발생할 수 있다.However, if the intervertebral disc is damaged due to aging, excessive movement, or poor posture, neurological symptoms such as a herniated disc or degenerative disc disease may occur.

이러한 신경 증상을 치료하기 위한 방법 중 하나로는, 손상된 추간판을 제거하고 인접한 두 개의 척추체 사이에 인공 구조물인 척추 유합용 임플란트를 삽입하여 추간판을 대체하는 척추 유합술이 있다.One way to treat these neurological symptoms is spinal fusion, which involves removing the damaged disc and replacing it with an artificial structure called a spinal implant between two adjacent vertebrae.

척추 유합술 중에서도 척추 내시경 수술은 주변 조직의 손상을 최소화할 수 있어 주목받고 있다.Among spinal fusion surgeries, endoscopic spinal surgery is attracting attention because it can minimize damage to surrounding tissues.

그러나 척추 내시경 수술 중 수술 부위에 생리 식염수가 가득 차 있는 상황에서, 척추 유합용 임플란트의 내부에 채워진 골이식재, 골형성 단백질, 펩타이드 등(이하 “골이식재”라고 함)이 생리 식염수에 의해 외부로 유출되는 문제가 발생할 수 있다. 이로 인해 골 성장의 저해됨에 따라 치료 효과가 떨어질 수 있다.However, during endoscopic spinal surgery, when the surgical site is filled with saline solution, bone grafting materials, bone morphogenetic proteins, peptides, etc. (hereinafter referred to as "bone grafting materials") filled inside the spinal fusion implant may leak out due to the saline solution. This may impede bone growth and reduce the therapeutic effect.

따라서, 척추 유합용 임플란트 내부에 채워진 골이식재가 외부로 유출되지 않고 보존된 상태를 유지하며 골 성장을 촉진할 수 있는 개선된 척추 유합용 임플란트가 요구된다.Therefore, an improved spinal fusion implant is required that can maintain the bone graft material filled inside the spinal fusion implant without leaking out and promote bone growth.

본 발명은 상기와 같은 문제점을 해결하기 위해 안출된 것으로서, 척추 유합용 임플란트 내부에 채워진 골이식재가 외부로 유출되지 않고 보존된 상태를 유지하며 골 성장을 촉진할 수 있는 척추 유합용 임플란트를 제공하는 것을 목적으로 한다.The present invention has been devised to solve the above problems, and its purpose is to provide a spinal fusion implant that can maintain a preserved state without bone graft material leaking out of the inside of the spinal fusion implant and promote bone growth.

본 발명의 과제들은 이상에서 언급한 과제로 제한되지 않으며, 언급되지 않은 또 다른 과제들은 아래의 기재로부터 당업자에게 명확하게 이해될 수 있을 것이다.The tasks of the present invention are not limited to the tasks mentioned above, and other tasks not mentioned will be clearly understood by those skilled in the art from the description below.

상기 과제를 해결하고자, 본 발명은 이웃하는 척추 뼈 사이에 배치되고, 트러스 구조를 형성하며 상기 척추 뼈를 지지하는 프레임 구조체; 및 상기 프레임 구조체의 내부 공간의 적어도 일부를 채우며 이웃하는 상기 척추 뼈와 접촉되는 다공성 구조체;를 포함하는 척추 유합용 임플란트를 본 발명의 일 실시예로 제시한다.In order to solve the above problem, the present invention proposes, as one embodiment, an implant for spinal fusion, comprising: a frame structure disposed between adjacent vertebrae, forming a truss structure and supporting the vertebrae; and a porous structure filling at least a portion of the internal space of the frame structure and coming into contact with the adjacent vertebrae.

또한, 상기 프레임 구조체는 상부 프레임; 상기 상부 프레임으로부터 이격되어 배치되는 하부 프레임; 및 상기 상부 프레임과 상기 하부 프레임 사이에 배치되며 절점이 형성되는 웹 프레임;을 포함할 수 있다.In addition, the frame structure may include an upper frame; a lower frame disposed spaced apart from the upper frame; and a web frame disposed between the upper frame and the lower frame and having a node formed therein.

또한, 상기 상부 프레임의 상면과 상기 하부 프레임의 하면에 이웃하는 상기 척추 뼈와 각각 접촉되는 요철부가 돌출 형성될 수 있다.Additionally, a protruding portion may be formed on the upper surface of the upper frame and the lower surface of the lower frame to contact the adjacent vertebrae, respectively.

또한, 상기 프레임 구조체는 일단부터 상기 척추 뼈 사이로 삽입되며 배치되고, 상기 상부 프레임과 상기 하부 프레임은 상기 상부 프레임 및 상기 하부 프레임의 일단 사이의 간격이 타단 사이의 간격보다 크도록 상기 프레임 구조체의 삽입 방향과 경사를 형성할 수 있다.In addition, the frame structure is inserted and placed between the vertebrae from one end, and the upper frame and the lower frame can form an insertion direction and an inclination of the frame structure such that the gap between one end of the upper frame and the lower frame is greater than the gap between the other ends.

또한, 상기 프레임 구조체는 상기 상부 프레임의 일단과 상기 하부 프레임의 일단을 연결하고, 상기 척추 뼈 사이로 삽입되는 방향으로 돌출되며 만곡지게 형성되는 전방 프레임; 및 상기 상부 프레임의 타단과 상기 하부 프레임의 타단을 연결하고, 수술기구와 착탈되는 결합부가 형성되는 후방 프레임;을 더 포함할 수 있다.In addition, the frame structure may further include a front frame that connects one end of the upper frame and one end of the lower frame, and is formed to be curved and protrude in a direction inserted between the vertebrae; and a rear frame that connects the other end of the upper frame and the other end of the lower frame, and has a connecting portion formed that is detachable from a surgical instrument.

또한, 상기 프레임 구조체는 상기 상부 프레임을 연결하는 상부 보강 프레임; 및 상기 하부 프레임을 연결하는 하부 보강 프레임;을 더 포함할 수 있다.In addition, the frame structure may further include an upper reinforcing frame connecting the upper frame; and a lower reinforcing frame connecting the lower frame.

또한, 상기 다공성 구조체는 공극을 형성하도록 소정의 길이와 두께로 서로 연결되는 스트럿을 포함하고, 상기 프레임 구조체의 평균 두께는 상기 스트럿의 평균 두께보다 두꺼울 수 있다.Additionally, the porous structure includes struts that are connected to each other with a predetermined length and thickness to form a gap, and the average thickness of the frame structure may be thicker than the average thickness of the struts.

한편, 본 발명은 이웃하는 척추 뼈 사이에 배치되어 상기 척추 뼈를 지지하는 프레임 구조체; 및 상기 프레임 구조체의 내부 공간의 적어도 일부를 채우며 상기 내부 공간에 주입된 골이식재를 가두는 다공성 구조체;를 포함할 수 있다.Meanwhile, the present invention may include a frame structure disposed between adjacent vertebrae to support the vertebrae; and a porous structure filling at least a portion of an internal space of the frame structure and confining a bone graft material injected into the internal space.

또한, 상기 다공성 구조체는, 소정의 길이와 두께로 서로 연결되는 스트럿을 포함함에 따라 다수의 공극을 형성할 수 있다.Additionally, the porous structure can form a plurality of pores by including struts that are connected to each other with a predetermined length and thickness.

또한, 상기 다공성 구조체는 상기 프레임 구조체의 상부 상에 배치되는 상부 접촉부와, 상기 프레임 구조체의 하부 상에 배치되는 하부 접촉부와, 상기 상부 접촉부 및 상기 하부 접촉부로부터 연장되는 중앙 연결부로 분획되고, 상기 중앙 연결부의 상기 공극의 평균크기는 상기 상부 접촉부 및 상기 하부 접촉부의 상기 공극의 평균크기보다 작을 수 있다.In addition, the porous structure is divided into an upper contact portion disposed on the upper part of the frame structure, a lower contact portion disposed on the lower part of the frame structure, and a central connecting portion extending from the upper contact portion and the lower contact portion, and the average size of the pores of the central connecting portion may be smaller than the average sizes of the pores of the upper contact portion and the lower contact portion.

또한, 상기 상부 접촉부, 상기 하부 접촉부 및 상기 중앙 연결부의 상기 공극의 평균크기는 0.1mm 내지 1.5mm 범위일 수 있다.Additionally, the average size of the gaps of the upper contact portion, the lower contact portion, and the central connecting portion may be in the range of 0.1 mm to 1.5 mm.

또한, 상기 상부 접촉부, 상기 하부 접촉부 및 상기 중앙 연결부의 공극률은 50% 내지 90% 범위이고, 상기 중앙 연결부는 상기 상부 접촉부 및 상기 하부 접촉부보다 더 큰 공극률을 가질 수 있다.Additionally, the porosity of the upper contact portion, the lower contact portion, and the central connecting portion is in the range of 50% to 90%, and the central connecting portion may have a greater porosity than the upper contact portion and the lower contact portion.

또한, 상부 접촉부, 상기 하부 접촉부와 상기 중앙 연결부 중 적어도 어느 하나에 상기 골이식재가 주입되는 주입홀이 형성될 수 있다.Additionally, an injection hole into which the bone graft material is injected may be formed in at least one of the upper contact portion, the lower contact portion, and the central connecting portion.

또한, 상기 프레임 구조체의 상부면의 적어도 일부는 상기 상부 접촉부보다 상방으로 돌출되고, 상기 프레임 구조체의 하부면의 적어도 일부는 상기 하부 접촉부보다 하방으로 돌출될 수 있다. Additionally, at least a portion of the upper surface of the frame structure may protrude upwardly from the upper contact portion, and at least a portion of the lower surface of the frame structure may protrude downwardly from the lower contact portion.

또한, 상기 상부 접촉부 및 상기 하부 접촉부의 표면은 상기 중앙 연결부의 표면보다 더 거친 면을 갖도록 형성될 수 있다.Additionally, the surfaces of the upper contact portion and the lower contact portion may be formed to have a rougher surface than the surface of the central connecting portion.

본 발명은 이웃하는 척추 뼈 사이에 삽입되어 척추 뼈가 유합되도록 할 수 있다.The present invention can be inserted between adjacent vertebrae to fuse the vertebrae.

또한, 본 발명은 생리 식염수에 의해 골이식재가 외부로 유출되지 않도록 함에 따라 척추 뼈 사이의 유합이 빠른 시일 내에 이루어지도록 골 성장을 촉진할 수 있다.In addition, the present invention can promote bone growth so that fusion between spinal bones can occur within a short period of time by preventing bone graft material from leaking out due to saline solution.

또한, 본 발명은 주변 골 조직의 유합을 용이하게 함과 동시에 척추 뼈를 안정적으로 지지할 수 있다.In addition, the present invention can stably support the spinal bone while facilitating the fusion of surrounding bone tissue.

또한, 본 발명은 척추 뼈의 구조 및 수술 조건에 따라 골이식재가 용이하게 주입될 수 있는 위치에 주입홀이 형성될 수 있다.In addition, the present invention can form an injection hole at a location where a bone graft material can be easily injected depending on the structure of the spinal bone and surgical conditions.

또한, 본 발명은 프레임 구조체가 척추 뼈를 지지함에 따라 척추 뼈의 움직임이나 척추 뼈로부터 전달되는 하중에 의해 다공성 구조체가 파손되는 것을 방지할 수 있다.In addition, the present invention can prevent the porous structure from being damaged by movement of the vertebrae or load transmitted from the vertebrae as the frame structure supports the vertebrae.

또한, 본 발명은 척추 뼈와 접촉하는 다공성 구조체의 접촉면이 거칠게 형성됨에 따라 척추 뼈의 골 성장을 촉진할 수 있다. In addition, the present invention can promote bone growth of the spinal bone by forming the contact surface of the porous structure in contact with the spinal bone rough.

또한, 본 발명은 척추 뼈 사이에 삽입된 상태에서 유동되지 않고 견고하게 고정될 수 있다.In addition, the present invention can be firmly fixed without moving while inserted between the vertebrae.

또한, 본 발명은 척추가 자연스러운 전만각과 후만각을 이룰 수 있도록 할 수 있다. Additionally, the present invention can enable the spine to form natural lordotic and kyphotic angles.

또한, 본 발명은 이웃하는 척추 뼈 사이에 용이하게 삽입될 수 있다.Additionally, the present invention can be easily inserted between adjacent vertebrae.

또한, 본 발명은 강도가 보강되는 구조를 가짐에 따라 척추 뼈로 전달되는 하중이 크더라도 이를 안정적으로 지지할 수 있다.In addition, since the present invention has a structure in which strength is reinforced, it can stably support even a large load transmitted to the spinal bone.

이상에서 살펴본 바와 같은 본 발명의 과제해결 수단에 의하면 다음과 같은 사항을 포함하는 다양한 효과를 기대할 수 있다. 다만, 본 발명이 하기와 같은 효과를 모두 발휘해야 성립되는 것은 아니다.According to the problem-solving means of the present invention as discussed above, various effects, including the following, can be expected. However, the present invention is not established only if it exhibits all of the following effects.

도 1은 본 발명의 일 실시예에 따른 척추 유합용 임플란트를 도시한 사시도,Figure 1 is a perspective view illustrating an implant for spinal fusion according to one embodiment of the present invention;

도 2는 도 1의 프레임 구조체의 내부에 배치된 다공성 구조체를 도시한 도면,Figure 2 is a drawing showing a porous structure arranged inside the frame structure of Figure 1;

도 3은 도 1의 측면도,Figure 3 is a side view of Figure 1;

도 4는 도 3의 웹 프레임의 구조를 도시한 도면,Figure 4 is a drawing showing the structure of the web frame of Figure 3.

도 5는 도 1의 척추 유합용 임플란트가 척추 뼈 사이에 삽입된 상태를 도시한 도면,Figure 5 is a drawing showing a state in which the spinal fusion implant of Figure 1 is inserted between the vertebrae.

도 6은 도 1의 저면도,Figure 6 is a bottom view of Figure 1;

도 7은 도 1의 영역 A를 확대하여 스트럿과 공극을 도시한 도면,Figure 7 is a drawing showing the strut and the gap by enlarging area A of Figure 1.

도 8은 도 2의 절단선 VIII-VIII에 따른 단면도,Fig. 8 is a cross-sectional view taken along the cutting line VIII-VIII of Fig. 2;

도 9는 상부 접촉부 또는 하부 접촉부의 일 부분을 확대한 도면,Fig. 9 is an enlarged view of a portion of the upper contact portion or the lower contact portion;

도 10은 중앙 연결부의 일 부분을 확대한 도면,Figure 10 is an enlarged view of a portion of the central connecting part.

도 11은 본 발명의 여러 실시예 중 주입홀이 상부 접촉부에 형성된 척추 유합용 임플란트를 도시한 도면,Figure 11 is a drawing showing an implant for spinal fusion in which an injection hole is formed in the upper contact portion among various embodiments of the present invention.

도 12는 본 발명의 여러 실시예 중 주입홀이 다수개로 형성되고 하부 보강 프레임이 평판 형태로 형성된 척추 유합용 임프란트를 도시한 도면,Figure 12 is a drawing showing an implant for spinal fusion in which a plurality of injection holes are formed and a lower reinforcing frame is formed in a flat shape among various embodiments of the present invention.

도 13은 본 발명의 여러 실시예 중 프레임 구조체의 후방 프레임이 돌출되며 만곡지게 형성되고 주입홀이 중앙 연결부에 형성된 척추 유합용 임플란트를 도시한 도면,FIG. 13 is a drawing showing an implant for spinal fusion in which the rear frame of the frame structure is formed to protrude and be curved among various embodiments of the present invention and an injection hole is formed in the central connecting portion.

도 14는 본 발명의 여러 실시예 중 프레임 구조체의 후방 프레임이 돌출되며 만곡지게 형성되고 주입홀이 다수개로 형성된 척추 유합용 임플란트를 도시한 도면,FIG. 14 is a drawing showing an implant for spinal fusion in which the rear frame of the frame structure is formed to protrude and be curved and a plurality of injection holes are formed among various embodiments of the present invention.

도 15는 본 발명의 척추 유합용 임플란트가 척추 뼈의 전방에 치우치게 배치된 상태를 도시한 도면,Figure 15 is a drawing showing a state in which the spinal fusion implant of the present invention is positioned in a way that it is tilted toward the front of the spinal bone.

도 16은 본 발명의 척추 유합용 임플란트가 척추 뼈 사이에 사선 형태로 배치된 상태를 도시한 도면,Figure 16 is a drawing showing a state in which the spinal fusion implant of the present invention is placed diagonally between the vertebrae.

도 17은 본 발명의 척추 유합용 임플란트가 척추 뼈 사이에 복수개로 배치된 상태를 도시한 도면이다.Figure 17 is a drawing showing a state in which multiple implants for spinal fusion of the present invention are placed between vertebrae.

본 발명의 이점 및 특징, 그리고 그것들을 달성하는 방법은 첨부되는 도면과 함께 상세하게 후술되어 있는 실시예들을 참조하면 명확해질 것이다. 그러나 본 발명은 이하에서 개시되는 실시예들에 한정되는 것이 아니라 서로 다른 다양한 형태로 구현될 수 있으며, 단지 본 실시예들은 본 발명의 개시가 완전하도록 하고, 본 발명이 속하는 기술분야에서 통상의 지식을 가진 자에게 발명의 범주를 완전하게 알려주기 위해 제공되는 것이며, 본 발명은 청구항의 범주에 의해 정의될 뿐이다. The advantages and features of the present invention, and the methods for achieving them, will become clearer with reference to the embodiments described in detail below together with the accompanying drawings. However, the present invention is not limited to the embodiments disclosed below and may be implemented in various different forms. These embodiments are provided solely to ensure that the disclosure of the present invention is complete and to fully inform those skilled in the art of the scope of the invention, and the present invention is defined solely by the scope of the claims.

또한, 본 명세서에서 기술하는 실시예들은 본 발명의 이상적인 예시도인 단면도 및/또는 개략도들을 참고하여 설명될 것이다. 따라서, 제조 기술 및/또는 허용 오차 등에 의해 예시도의 형태가 변형될 수 있다. 또한, 본 발명에 도시된 각 도면에 있어서 각 구성 요소들은 설명의 편의를 고려하여 다소 확대 또는 축소되어 도시된 것일 수 있다. 명세서 전체에 걸쳐 동일 참조 부호는 동일 구성 요소를 지칭한다.Furthermore, the embodiments described herein will be described with reference to cross-sectional and/or schematic drawings, which are ideal illustrations of the present invention. Therefore, the form of the illustrations may be modified due to manufacturing techniques and/or tolerances. Furthermore, in each drawing illustrated in the present invention, each component may be depicted somewhat enlarged or reduced for convenience of explanation. Throughout the specification, the same reference numerals denote the same components.

도면에서 전방은 양의 x축과 평행한 방향이고, 후방은 음의 x축과 평행한 방향이다. 상방은 양의 y축과 평행한 방향이고, 하방은 음의 y축과 평행한 방향이다. In the drawing, forward is the direction parallel to the positive x-axis, and backward is the direction parallel to the negative x-axis. Up is the direction parallel to the positive y-axis, and down is the direction parallel to the negative y-axis.

본 발명의 척추 유합용 임플란트를 기준으로, 이웃하는 척추 뼈 중에서 상부에 위치하는 척추 뼈를 상부 척추뼈로, 하부에 위치하는 척추 뼈를 하부 척추 뼈로 지칭한다.Based on the spinal fusion implant of the present invention, the vertebra located above the neighboring vertebrae is referred to as the upper vertebrae, and the vertebra located below is referred to as the lower vertebrae.

이하, 도면을 참조하여 본 발명의 구체적인 실시예를 상세히 설명한다.Hereinafter, specific embodiments of the present invention will be described in detail with reference to the drawings.

도 1은 본 발명의 일 실시예에 따른 척추 유합용 임플란트를 도시한 사시도, 도 2는 도 1의 프레임 구조체의 내부에 배치된 다공성 구조체를 도시한 도면이다.FIG. 1 is a perspective view illustrating an implant for spinal fusion according to one embodiment of the present invention, and FIG. 2 is a drawing illustrating a porous structure arranged inside the frame structure of FIG. 1.

도 1과 도 2를 참고하면, 본 발명의 일 실시예에 따른 척추 유합용 임플란트(10)는 이웃하는 척추 뼈 사이에 삽입되어 골 성장을 촉진하는 것으로, 프레임 구조체(100)와 다공성 구조체(200)를 포함한다. Referring to FIGS. 1 and 2, an implant (10) for spinal fusion according to one embodiment of the present invention is inserted between adjacent vertebrae to promote bone growth, and includes a frame structure (100) and a porous structure (200).

도 3은 도 1의 측면도이다.Figure 3 is a side view of Figure 1.

도 1과 도 3을 참고하면, 프레임 구조체(100)는 이웃하는 척추 뼈 사이로 삽입되어 척추 뼈를 지지하는 것으로, 척추 뼈로 전달되는 하중을 지지하기 위해 트러스 구조를 형성할 수 있다. 프레임 구조체(100)는 하중을 지지할 수 있고 생체 적합성을 갖춘 금속 분말 또는 고분자 분말로 제작되는 것이 바람직하다. 따라서 프레임 구조체(100)는 티타늄, 티타늄 합금, 코발트-크롬 합금, 탄탈럼, 마그네슘 등으로 제작될 수 있다. Referring to FIGS. 1 and 3, a frame structure (100) is inserted between adjacent vertebrae to support the vertebrae, and can form a truss structure to support the load transferred to the vertebrae. The frame structure (100) is preferably made of a metal powder or polymer powder that can support the load and has biocompatibility. Accordingly, the frame structure (100) can be made of titanium, a titanium alloy, a cobalt-chromium alloy, tantalum, magnesium, or the like.

프레임 구조체(100)는 상부 프레임(110), 하부 프레임(120), 웹 프레임(130), 전방 프레임(140), 후방 프레임(150), 상부 보강 프레임(161) 및 하부 보강 프레임(162)을 포함할 수 있다. The frame structure (100) may include an upper frame (110), a lower frame (120), a web frame (130), a front frame (140), a rear frame (150), an upper reinforcing frame (161), and a lower reinforcing frame (162).

상부 프레임(110)은 상부 척추 뼈를 지지하는 것으로, 소정의 길이와 두께를 갖도록 형성될 수 있다. 예를 들어, 상부 프레임(110)은 복수 개가 마련될 수 있고, 일 예로, 서로 평행하게 이격 배치되는 한 쌍으로 형성될 수 있다.The upper frame (110) supports the upper spine and may be formed to have a predetermined length and thickness. For example, a plurality of upper frames (110) may be provided, and for example, they may be formed as a pair spaced apart from each other and parallel to each other.

복수 개의 상부 프레임(110), 일 예로, 한 쌍의 상부 프레임(110) 사이에 상부 보강 프레임(161)이 배치됨으로써, 상부 프레임(110) 간의 연결이 강화되며 지지력이 보강될 수 있다.By placing an upper reinforcing frame (161) between a plurality of upper frames (110), for example, a pair of upper frames (110), the connection between the upper frames (110) can be strengthened and the supporting force can be reinforced.

상부 프레임(110)의 적어도 일부는 후술하는 다공성 구조체(200)의 상부 접촉부(230, 도8 참고)보다 상방으로 돌출 형성될 수 있다. 상부 프레임(110)의 적어도 일부가 돌출 형성됨으로써, 상부 척추 뼈로 전달되는 하중에 의한 다공성 구조체(200)의 파손이 방지될 수 있다.At least a portion of the upper frame (110) may be formed to protrude upward from the upper contact portion (230, see FIG. 8) of the porous structure (200) described later. By forming at least a portion of the upper frame (110) to protrude, damage to the porous structure (200) due to a load transmitted to the upper spinal bone can be prevented.

예를 들어 상부 프레임(110)의 상면에 요철부(111)가 형성될 수 있다. 요철부(111)는 상부 척추 뼈와 접촉되며, 본 발명의 척추 유합용 임플란트(10)가 상하부 척추 뼈 사이에 삽입된 상태에서 위치가 고정될 수 있도록 할 수 있다.For example, a protruding portion (111) may be formed on the upper surface of the upper frame (110). The protruding portion (111) comes into contact with the upper vertebrae and may allow the spinal fusion implant (10) of the present invention to be fixed in position while inserted between the upper and lower vertebrae.

요철부(111)는 끝이 평평한 나사산의 형태, 정상면이 평평한 파 형태 등으로 형성될 수 있다. 요철부(111)의 평평한 부분은 상부 척추 뼈의 손상을 최소화하며 상부 척추 뼈를 지지할 수 있다. The uneven portion (111) can be formed in the shape of a screw thread with a flat end, a wave shape with a flat top surface, etc. The flat portion of the uneven portion (111) can minimize damage to the upper vertebrae and support the upper vertebrae.

하부 프레임(120)은 하부 척추 뼈를 지지하는 것으로, 소정의 길이와 두께를 갖도록 형성될 수 있다. 하부 프레임(120)은 복수 개가 마련될 수 있고, 일 예로, 서로 평행하게 이격 배치되는 한 쌍으로 형성될 수 있다. 하부 프레임(120)은 상부 프레임(110)과 대응되게 배치될 수 있다. The lower frame (120) supports the lower spine and may be formed to have a predetermined length and thickness. A plurality of lower frames (120) may be provided, and for example, they may be formed as a pair spaced apart and parallel to each other. The lower frames (120) may be arranged to correspond to the upper frame (110).

복수 개의 하부 프레임(120), 일 예로, 한 쌍의 하부 프레임(120) 사이에 하부 보강 프레임(162)이 배치됨으로써, 하부 프레임(120) 간의 연결이 강화되며 지지력이 보강될 수 있다.By placing a lower reinforcing frame (162) between a plurality of lower frames (120), for example, a pair of lower frames (120), the connection between the lower frames (120) can be strengthened and the supporting force can be reinforced.

하부 프레임(120)의 적어도 일부는 후술하는 다공성 구조체(200)의 하부 접촉부(240, 도 8 참고)보다 하방으로 돌출 형성될 수 있다. 하부 프레임(120)의 적어도 일부가 돌출 형성됨으로써 하부 척추 뼈로 전달되는 하중에 의한 다공성 구조체(200)의 파손이 방지될 수 있다.At least a portion of the lower frame (120) may be formed to protrude downward from the lower contact portion (240, see FIG. 8) of the porous structure (200) described below. By forming at least a portion of the lower frame (120) to protrude, damage to the porous structure (200) due to a load transmitted to the lower vertebrae can be prevented.

예를 들어 하부 프레임(120)의 하면에 요철부(121)가 형성될 수 있다. 요철부(121)는 하부 척추 뼈와 접촉되며, 본 발명의 척추 유합용 임플란트(10)가 상하부 척추 뼈 사이에 삽입된 상태에서 위치가 고정되도록 할 수 있다. For example, a protruding portion (121) may be formed on the lower surface of the lower frame (120). The protruding portion (121) comes into contact with the lower vertebrae, and can fix the position of the spinal fusion implant (10) of the present invention while it is inserted between the upper and lower vertebrae.

요철부(121)는 끝이 평평한 나사산의 형태, 정상면이 평평한 파 형태 등으로 형성될 수 있다. 요철부(121)의 평평한 부분은 하부 척추 뼈의 손상을 최소화하며 하부 척추 뼈를 지지할 수 있다.The uneven portion (121) can be formed in the shape of a screw thread with a flat end, a wave shape with a flat top surface, etc. The flat portion of the uneven portion (121) can minimize damage to the lower vertebrae and support the lower vertebrae.

도 4는 도 3의 웹 프레임의 구조를 도시한 도면이다.Figure 4 is a drawing illustrating the structure of the web frame of Figure 3.

도 3과 도 4를 참고하면, 웹 프레임(130)은 상부 프레임(110)과 하부 프레임(120) 사이에 배치되며 상부 프레임(110)과 하부 프레임(120)을 지지하는 트러스 구조를 형성할 수 있다. 복수개의 웹 프레임(130)은 서로 연결되며 대략 삼각 형상의 트러스 구조를 형성할 수 있다. 웹 프레임(130)은 서로 간의 연결 및/또는 상부 프레임(110)과 하부 프레임(120)과의 연결로 형성되는 절점(131)을 포함할 수 있다.Referring to FIGS. 3 and 4, a web frame (130) may be positioned between an upper frame (110) and a lower frame (120) and may form a truss structure supporting the upper frame (110) and the lower frame (120). A plurality of web frames (130) may be connected to each other and may form a truss structure having an approximately triangular shape. The web frames (130) may include nodes (131) formed by connections between each other and/or between the upper frame (110) and the lower frame (120).

웹 프레임(130)의 트러스 구조는 상부 프레임(110)과 하부 프레임(120)으로부터 전달되는 하중을 고르게 분산시킴으로써, 안정적으로 척추 뼈를 지지할 수 있다. 웹 프레임(130)을 포함한 프레임 구조체(100)가 척추 뼈로 전달되는 하중을 지지함으로써, 하중에 의해 다공성 구조체(200)가 파손되는 것을 방지할 수 있다.The truss structure of the web frame (130) can stably support the spinal column by evenly distributing the load transferred from the upper frame (110) and the lower frame (120). Since the frame structure (100) including the web frame (130) supports the load transferred to the spinal column, the porous structure (200) can be prevented from being damaged by the load.

웹 프레임(130)은 상부 프레임(110)과 하부 프레임(120)의 길이에 따라 적어도 1개 이상의 트러스 구조를 형성할 수 있다. 웹 프레임(130) 사이에 후술하는 주입홀(260)이 형성될 수 있다. 주입홀(260)에 대해서는 후술한다.The web frame (130) can form at least one truss structure depending on the length of the upper frame (110) and the lower frame (120). An injection hole (260), which will be described later, can be formed between the web frames (130). The injection hole (260) will be described later.

도 5는 도 1의 척추 유합용 임플란트가 척추 뼈 사이에 삽입된 상태를 도시한 도면이다.Figure 5 is a drawing showing the spinal fusion implant of Figure 1 inserted between the vertebrae.

도 3과 도 5를 참고하면, 프레임 구조체(100)의 상부 프레임(110)과 하부 프레임(120)은 삽입 방향과 경사를 형성할 수 있다. 삽입 방향은 상부 프레임(110)의 일단과 하부 프레임(120)의 일단이 전방을 향하며 척추 뼈 사이로 삽입되는 방향이다.Referring to FIGS. 3 and 5, the upper frame (110) and the lower frame (120) of the frame structure (100) can form an insertion direction and an incline. The insertion direction is a direction in which one end of the upper frame (110) and one end of the lower frame (120) face forward and are inserted between the vertebrae.

예를 들어, 상부 프레임(110)의 일단은 상부 프레임(110)의 최전방에 배치되는 요철부(111)의 전방 말단의 위치를 지칭하거나, 전방 프레임(140)과 연결되는 부분을 지칭할 수 있다. 하부 프레임(120)의 일단은 하부 프레임(120)의 최전방에 배치되는 요철부(121)의 전방 말단의 위치를 지칭하거나, 전방 프레임(140)과 연결되는 부분을 지칭할 수 있다.For example, one end of the upper frame (110) may refer to the position of the front end of the uneven portion (111) positioned at the frontmost part of the upper frame (110), or may refer to a portion connected to the front frame (140). One end of the lower frame (120) may refer to the position of the front end of the uneven portion (121) positioned at the frontmost part of the lower frame (120), or may refer to a portion connected to the front frame (140).

한편, 상부 프레임(110)의 타단은 상부 프레임(110)의 최후방에 배치되는 요철부(111)의 후방 말단의 위치를 지칭하거나, 후방 프레임(150)과 연결되는 부분을 지칭할 수 있다. 하부 프레임(120)의 타단은 하부 프레임(120)의 최후방에 배치되는 요철부(121)의 후방 말단의 위치를 지칭하거나, 후방 프레임(150)과 연결되는 부분을 지칭할 수 있다.Meanwhile, the other end of the upper frame (110) may refer to the position of the rear end of the uneven portion (111) positioned at the rearmost end of the upper frame (110), or may refer to a portion connected to the rear frame (150). The other end of the lower frame (120) may refer to the position of the rear end of the uneven portion (121) positioned at the rearmost end of the lower frame (120), or may refer to a portion connected to the rear frame (150).

즉 상부 프레임(110)의 일단과 하부 프레임(120)의 일단은 척추 뼈 사이로 삽입 시 상부 프레임(110)과 하부 프레임(120) 중에서 가장 먼저 진입하는 부분일 수 있다. 상부 프레임(110)의 타단과 하부 프레임(120)의 타단은 척추 뼈 사이로 삽입 시 상부 프레임(110)과 하부 프레임(120) 중에서 가장 나중에 진입하는 부분일 수 있다.That is, one end of the upper frame (110) and one end of the lower frame (120) may be the first parts to enter between the vertebrae among the upper frame (110) and the lower frame (120). The other end of the upper frame (110) and the other end of the lower frame (120) may be the last parts to enter between the vertebrae among the upper frame (110) and the lower frame (120).

도 3을 참고하면, 상부 프레임(110)의 일단과 하부 프레임(120)의 일단 사이의 간격이 상부 프레임(110)의 타단과 하부 프레임(120)의 타단 사이의 간격보다 클 수 있다. 즉 상부 프레임(110)과 하부 프레임(120)은 삽입 방향과 경사를 이루도록 배치됨으로써, 척추 뼈가 자연스러운 전만각과 후만각을 이룰 수 있도록 할 수 있다. Referring to FIG. 3, the gap between one end of the upper frame (110) and one end of the lower frame (120) may be greater than the gap between the other end of the upper frame (110) and the other end of the lower frame (120). That is, the upper frame (110) and the lower frame (120) are arranged to form an insertion direction and an incline, thereby allowing the spinal bones to form natural lordotic and kyphotic angles.

이에 따라 본 발명의 척추 유합용 임플란트(10)가 삽입된 척추 뼈는 수술 전의 이상 없는 척추 뼈처럼 S자 형태로 자연스럽게 구부러질 수 있다. 이에 더하여, 상부 프레임(110)과 하부 프레임(120)은 접촉하는 척추 뼈의 형상에 대응한 부드러운 곡면을 포함함으로써, 수술 후에 척추 뼈는 더욱 자연스럽게 구부러질 수 있다.Accordingly, the spinal bone into which the spinal fusion implant (10) of the present invention is inserted can naturally bend into an S shape like a normal spinal bone before surgery. In addition, the upper frame (110) and the lower frame (120) include soft curved surfaces corresponding to the shape of the spinal bone they contact, so that the spinal bone can bend more naturally after surgery.

도 1과 도 3을 참고하면, 전방 프레임(140)은 척추 뼈 사이로의 삽입을 용이하게 하는 것으로, 상부 프레임(110)의 일단과 하부 프레임(120)의 일단을 연결하며 삽입 방향으로 돌출 형성될 수 있다. 전방 프레임(140)은 전방으로 돌출되며 만곡지게 형성됨으로써, 프레임 구조체(100)는 전체적으로 유선형에 가까운 형태가 될 수 있다.Referring to FIGS. 1 and 3, the front frame (140) is configured to connect one end of the upper frame (110) and one end of the lower frame (120) to facilitate insertion between the vertebrae and may be formed to protrude in the insertion direction. The front frame (140) protrudes forward and is formed to be curved, so that the frame structure (100) can have a shape close to a streamlined shape overall.

후방 프레임(150)은 웹 프레임(130)과 함께 상부 프레임(110)과 하부 프레임(120)을 지지하는 것으로, 상부 프레임(110)의 타단과 하부 프레임(120)의 타단을 연결할 수 있다. The rear frame (150) supports the upper frame (110) and the lower frame (120) together with the web frame (130), and can connect the other end of the upper frame (110) and the other end of the lower frame (120).

후방 프레임(150)은 수술기구와 착탈되는 결합부(151, 도 6 참고)가 형성될 수 있다. 수술기구는 본 발명의 척추 유합용 임플란트(10)가 삽입 방향으로 전진할 수 있도록 밀어주는 기구를 의미한다.The rear frame (150) may be formed with a connecting portion (151, see Fig. 6) that is detachable from a surgical instrument. The surgical instrument refers to a mechanism that pushes the spinal fusion implant (10) of the present invention so that it can advance in the insertion direction.

결합부(151)는 볼팅 체결 방식(도 8 참고), 핀 체결 방식, 끼워맞춤 방식, 자성 결합 방식 등 다양한 방식으로 수술기구와 결합될 수 있다. The connecting part (151) can be connected to the surgical instrument in various ways, such as a bolting connection method (see Fig. 8), a pin connection method, a fitting method, or a magnetic connection method.

도 1을 참고하면, 상부 보강 프레임(161)은 상부 프레임(110) 간의 연결을 견고하게 함과 동시에 상부 프레임(110)의 지지력을 보강하는 것으로, 한 쌍의 상부 프레임(110) 사이에 배치될 수 있다. 상부 보강 프레임(161)은 전술한 상부 프레임(110)의 요철부(111)보다 돌출되지 않게 형성될 수 있다.Referring to Fig. 1, an upper reinforcing frame (161) may be placed between a pair of upper frames (110) to reinforce the connection between the upper frames (110) and at the same time reinforce the supporting force of the upper frames (110). The upper reinforcing frame (161) may be formed so as not to protrude further than the uneven portion (111) of the upper frame (110) described above.

상부 보강 프레임(161)은 상부 프레임(110)과 수직하거나 사선 형태로 배치될 수 있다. 지지력 보강을 위해, 상부 보강 프레임(161)은 다수개로 배치되는 것이 바람직하다.The upper reinforcing frame (161) may be arranged perpendicular to or diagonally relative to the upper frame (110). To reinforce the supporting force, it is preferable that the upper reinforcing frames (161) be arranged in multiple pieces.

도 6은 도 1의 저면도이다.Figure 6 is a bottom view of Figure 1.

도 6을 참고하면, 하부 보강 프레임(162)은 하부 프레임(120) 간의 연결을 견고하게 함과 동시에 하부 프레임(120)의 지지력을 보강하는 것으로, 한 쌍의 하부 프레임(120) 사이에 배치될 수 있다. 하부 보강 프레임(162)은 전술한 하부 프레임(120)의 요철부(121)보다 돌출되지 않게 형성될 수 있다.Referring to Fig. 6, the lower reinforcing frame (162) may be placed between a pair of lower frames (120) to reinforce the connection between the lower frames (120) and at the same time reinforce the supporting force of the lower frames (120). The lower reinforcing frame (162) may be formed so as not to protrude further than the uneven portion (121) of the lower frame (120) described above.

하부 보강 프레임(162)은 하부 프레임(120)과 수직하거나 사선 형태로 배치될 수 있다. 지지력 보강을 위해, 하부 보강 프레임(162)은 다수개로 배치되는 것이 바람직하다.The lower reinforcing frame (162) may be arranged perpendicular to or diagonally relative to the lower frame (120). To reinforce the supporting force, it is preferable that the lower reinforcing frames (162) be arranged in multiple pieces.

한편, 프레임 구조체(100)는 후술하는 다공성 구조체(200)의 스트럿(210)의 평균 두께보다 더 두꺼운 평균 두께를 갖도록 형성될 수 있다. 프레임 구조체(100)는 척추 뼈로 전달되는 하중을 지지하기 위해, 다공성 구조체(200)의 스트럿(210)보다 더 두꺼운 두께로 형성되는 것이 바람직하다.Meanwhile, the frame structure (100) may be formed to have an average thickness that is thicker than the average thickness of the struts (210) of the porous structure (200) described later. It is preferable that the frame structure (100) be formed to have a thickness that is thicker than the struts (210) of the porous structure (200) in order to support the load transmitted to the spinal bone.

특히 상부 보강 프레임(161) 및 하부 보강 프레임(162)의 두께가 스트럿(210)의 두께보다 더 두껍게 형성됨으로써, 스트럿(210)이 상부 보강 프레임(161) 및 하부 보강 프레임(162)을 감싸며 형성될 수 있다. 스트럿(210)이 상부 보강 프레임(161) 및 하부 보강 프레임(162)을 감싸는 형태로 형성됨으로써, 프레임 구조체(100)가 다공성 구조체(200)를 수용하는 수용력이 강화될 수 있다.In particular, since the thickness of the upper reinforcing frame (161) and the lower reinforcing frame (162) is formed thicker than the thickness of the strut (210), the strut (210) can be formed to surround the upper reinforcing frame (161) and the lower reinforcing frame (162). Since the strut (210) is formed to surround the upper reinforcing frame (161) and the lower reinforcing frame (162), the capacity of the frame structure (100) to accommodate the porous structure (200) can be strengthened.

도 1과 도 2를 참고하면, 다공성 구조체(200)는 프레임 구조체(100)의 내부 공간에 주입된 골이식재를 가두고 골 성장을 촉진하는 것으로, 프레임 구조체(100)의 내부 공간의 일부를 채우며 형성될 수 있다. 다공성 구조체(200)는 척추 뼈로부터 전달되는 하중을 지지하지 않으면서 척추 뼈와 접촉하며, 척추 뼈의 골 성장을 촉진할 수 있다. Referring to FIGS. 1 and 2, the porous structure (200) can be formed by filling a portion of the internal space of the frame structure (100) to confine the bone graft material injected into the internal space of the frame structure (100) and promote bone growth. The porous structure (200) can contact the vertebrae without supporting the load transmitted from the vertebrae and promote bone growth of the vertebrae.

다공성 구조체(200)는 3D 프린팅 방식으로 적층되며 거친 면을 갖도록 형성될 수 있다. 다공성 구조체(200)의 거친 면이 척추 뼈와 접촉됨으로써, 골 성장이 촉진될 수 있다.The porous structure (200) can be formed by laminating using a 3D printing method and having a rough surface. By having the rough surface of the porous structure (200) come into contact with the spinal bone, bone growth can be promoted.

도 7은 도 1의 영역 A를 확대하여 스트럿과 공극을 도시한 도면이다.Figure 7 is a drawing showing the strut and the gap by enlarging area A of Figure 1.

도 7을 참고하면, 다공성 구조체(200)는 소정의 길이와 두께로 형성되는 스트럿(210)을 포함할 수 있다. 스트럿(210)은 서로 연결되며 다수의 공극(220)을 형성할 수 있다. 스트럿(210)의 일단과 타단은 다른 스트럿(210)의 일단 또는 타단과 연결될 수 있다.Referring to FIG. 7, the porous structure (200) may include struts (210) formed with a predetermined length and thickness. The struts (210) may be connected to each other to form a plurality of voids (220). One end and the other end of a strut (210) may be connected to one end or the other end of another strut (210).

도 8은 도 2의 절단선 VIII-VIII에 따른 단면도이다.Fig. 8 is a cross-sectional view taken along the cutting line VIII-VIII of Fig. 2.

도 8을 참고하면, 다공성 구조체(200)는 상부 접촉부(230), 하부 접촉부(240) 및 중앙 연결부(250)로 분획될 수 있다.Referring to FIG. 8, the porous structure (200) can be divided into an upper contact portion (230), a lower contact portion (240), and a central connection portion (250).

상부 접촉부(230)는 프레임 구조체(100)의 상부에 배치되며 상부 척추 뼈와 접촉되는 부분으로, 소정의 두께를 갖는 일정 영역이다.The upper contact portion (230) is placed on the upper portion of the frame structure (100) and is a portion that comes into contact with the upper spinal bone, and is a predetermined area having a predetermined thickness.

하부 접촉부(240)는 프레임 구조체(100)의 하부에 배치되며 하부 척추 뼈와 접촉되는 부분으로, 소정의 두께를 갖는 일정 영역이다.The lower contact portion (240) is placed at the lower portion of the frame structure (100) and is a portion that comes into contact with the lower spine, and is a predetermined area having a predetermined thickness.

중앙 연결부(250)는 상부 접촉부(230)와 하부 접촉부(240) 사이에 배치되며 상부 접촉부(230) 및 하부 접촉부(240)로부터 연장되는 부분으로, 상부 접촉부(230)와 하부 접촉부(240)를 제외한 나머지 영역이다.The central connecting portion (250) is positioned between the upper contact portion (230) and the lower contact portion (240), and is a portion extending from the upper contact portion (230) and the lower contact portion (240), and is the remaining area excluding the upper contact portion (230) and the lower contact portion (240).

상부 접촉부(230)와 하부 접촉부(240)는 척추 뼈와 접촉되며 골 성장이 촉진되도록 할 수 있다. 따라서 상부 접촉부(230)와 하부 접촉부(240)는 중앙 연결부(250)의 표면보다 더 거친 표면을 갖도록 형성될 수 있다. The upper contact portion (230) and the lower contact portion (240) come into contact with the spinal bone and can promote bone growth. Therefore, the upper contact portion (230) and the lower contact portion (240) can be formed to have a rougher surface than the surface of the central connecting portion (250).

또한 상부 접촉부(230)와 하부 접촉부(240)는 삽입되는 척추 뼈의 탄성계수에 따라 그에 부합하는 탄성계수를 갖도록 형성될 수 있다. 상부 접촉부(230)와 하부 접촉부(240)는 뼈 침강(subsidence) 현상을 방지하기 위해, 척추 뼈의 탄성계수와 동일하거나 근사한 탄성계수 0.1GPa 내지 10GPa 범위 내에서 형성될 수 있다. 뼈 침강 현상은 척추 유합용 임플란트(10)가 척추 뼈 안으로 내려 앉으면서 척추 뼈 사이의 간격이 줄어드는 현상이다.In addition, the upper contact portion (230) and the lower contact portion (240) may be formed to have an elastic modulus that matches the elastic modulus of the inserted vertebra. The upper contact portion (230) and the lower contact portion (240) may be formed to have an elastic modulus within a range of 0.1 GPa to 10 GPa, which is the same as or close to the elastic modulus of the vertebra, in order to prevent bone subsidence. The bone subsidence phenomenon is a phenomenon in which the gap between the vertebrae decreases as the spinal fusion implant (10) descends into the vertebrae.

도 9는 상부 접촉부 또는 하부 접촉부의 일 부분을 확대한 도면, 도 10은 중앙 연결부의 일 부분을 확대한 도면이다.Fig. 9 is an enlarged view of a portion of the upper contact portion or the lower contact portion, and Fig. 10 is an enlarged view of a portion of the central connecting portion.

도 9과 도 10을 참고하면, 중앙 연결부(250)는 공극(220)의 평균크기가 상부 접촉부(230) 및 하부 접촉부(240)의 공극(220)의 평균크기보다 작도록 형성되며 공극(220)의 평균크기는 0.1mm 내지 1.5mm범위일 수 있다. 중앙 연결부(250)가 상부 접촉부(230) 및 하부 접촉부(240)의 공극(220)보다 작은 공극(220)을 갖도록 치밀하게 형성됨으로써, 골이식재의 유출이 방지됨과 동시에, 상부 접촉부(230)와 하부 접촉부(240)로의 골 조직의 침투가 용이해질 수 있다. Referring to FIGS. 9 and 10, the central connecting portion (250) is formed so that the average size of the gap (220) is smaller than the average sizes of the gaps (220) of the upper contact portion (230) and the lower contact portion (240), and the average size of the gap (220) may be in the range of 0.1 mm to 1.5 mm. By densely forming the central connecting portion (250) to have a gap (220) smaller than the gaps (220) of the upper contact portion (230) and the lower contact portion (240), the outflow of the bone graft material is prevented, and at the same time, the penetration of bone tissue into the upper contact portion (230) and the lower contact portion (240) can be facilitated.

특히 골이식재가 외부로 유출되지 않고 보존됨에 따라, 기존의 척추 유합용 임플란트(10)보다 골 성장이 촉진되며 척추 뼈 사이의 유합이 빠른 시일 내에 이루어질 수 있다.In particular, since the bone graft material is preserved without leaking out, bone growth is promoted compared to the existing spinal fusion implant (10) and fusion between spinal bones can be achieved within a short period of time.

예를 들어, 상부 접촉부(230), 하부 접촉부(240) 및 중앙 연결부(250)의 공극률은 50% 내지 90%이고, 중앙 연결부(250)는 상부 접촉부(230) 및 하부 접촉부(240)보다 더 큰 공극률을 갖는 것이 바람직하다. 이에 따라 골이식재의 유출방지 효과와 골 조직의 침투 효과가 더욱 향상될 수 있다.For example, the porosity of the upper contact portion (230), the lower contact portion (240), and the central connection portion (250) is preferably 50% to 90%, and the central connection portion (250) preferably has a greater porosity than the upper contact portion (230) and the lower contact portion (240). Accordingly, the effect of preventing the outflow of the bone graft material and the effect of infiltrating the bone tissue can be further improved.

그리고 상부 접촉부(230), 하부 접촉부(240)와 중앙 연결부(250)의 경계 부위에서 공극(220)은 점차적으로 크기가 변화되며 형성될 수 있다. 즉 공극(220)의 크기는 상부 접촉부(230)와 하부 접촉부(240)에서 중앙 연결부(250)로 갈수록 점차적으로 작아질 수 있다.And, at the boundary portion of the upper contact portion (230), the lower contact portion (240), and the central connection portion (250), a gap (220) can be formed with a gradually changing size. That is, the size of the gap (220) can gradually become smaller as it goes from the upper contact portion (230) and the lower contact portion (240) to the central connection portion (250).

도 1과 도 2를 참고하면, 골이식재가 주입되는 주입홀(260)은 상부 접촉부(230), 하부 접촉부(240) 및 중앙 연결부(250) 중 적어도 어느 하나에 형성될 수 있다.Referring to FIGS. 1 and 2, an injection hole (260) into which a bone graft material is injected may be formed in at least one of the upper contact portion (230), the lower contact portion (240), and the central connection portion (250).

주입홀(260)은 척추 뼈의 구조 및 수술 조건에 따라 크기와 위치를 달리하며 다수개로 형성되거나 하나만 형성될 수 있다. 주입홀(260)의 개수가 적어질수록, 골이식재가 유출될 가능성은 낮아질 수 있다. 도 1 및 도 2에 중앙 연결부(250)의 일 측면에 주입홀(260)이 형성되는 것으로 도시되었으나, 이에 한정되지 않는다.The injection holes (260) may be formed in multiples or in singles, with different sizes and locations depending on the structure of the spinal bone and surgical conditions. The fewer the number of injection holes (260), the lower the likelihood of bone graft material leakage. While FIGS. 1 and 2 illustrate that the injection holes (260) are formed on one side of the central connecting portion (250), the present invention is not limited thereto.

도 11은 본 발명의 여러 실시예 중 주입홀이 상부 접촉부에 형성된 척추 유합용 임플란트를 도시한 도면, 도 12는 본 발명의 여러 실시예 중 주입홀이 다수개로 형성되고 하부 보강 프레임이 평판 형태로 형성된 척추 유합용 임프란트를 도시한 도면, 도 13은 본 발명의 여러 실시예 중 프레임 구조체의 후방 프레임이 돌출되며 만곡지게 형성되고 주입홀이 중앙 연결부에 형성된 척추 유합용 임플란트를 도시한 도면, 도 14는 본 발명의 여러 실시예 중 프레임 구조체의 후방 프레임이 돌출되며 만곡지게 형성되고 주입홀이 다수개로 형성된 척추 유합용 임플란트를 도시한 도면이다.FIG. 11 is a drawing illustrating a spinal fusion implant having an injection hole formed in an upper contact portion among various embodiments of the present invention, FIG. 12 is a drawing illustrating a spinal fusion implant having a plurality of injection holes formed and a lower reinforcing frame formed in a flat shape among various embodiments of the present invention, FIG. 13 is a drawing illustrating a spinal fusion implant having a rear frame of a frame structure formed to protrude and be curved and an injection hole formed in a central connecting portion among various embodiments of the present invention, FIG. 14 is a drawing illustrating a spinal fusion implant having a rear frame of a frame structure formed to protrude and be curved and a plurality of injection holes formed among various embodiments of the present invention.

도 11 내지 도 14를 참고하면, 본 발명은 척추 뼈의 형태에 부합되는 형태로 형성되는 프레임 구조체(100)와 상대적으로 작은 공극(220)을 갖는 중앙 연결부(250)를 포함하는 다공성 구조체(200)를 포함하며 여러 형태로 실시될 수 있다. Referring to FIGS. 11 to 14, the present invention includes a frame structure (100) formed in a shape conforming to the shape of a spinal bone and a porous structure (200) including a central connecting portion (250) having a relatively small gap (220), and can be implemented in various forms.

도 11을 참고하면, 본 발명은 주입홀(260)이 상부 접촉부(230)에 하방으로 소정의 깊이를 갖도록 형성된 척추 유합용 임플란트(10)로 실시될 수 있다.Referring to FIG. 11, the present invention can be implemented as an implant (10) for spinal fusion in which an injection hole (260) is formed to have a predetermined depth downward from an upper contact portion (230).

도 12를 참고하면, 본 발명은 주입홀(260)이 상부 접촉부(230)와 중앙 연결부(250)에 다수개로 형성된 척추 유합용 임플란트(10)로 실시될 수 있다. 또한 하부 보강 프레임(162)은 바(bar) 형태가 아닌 평판 형태일 수 있다.Referring to Fig. 12, the present invention can be implemented as a spinal fusion implant (10) in which multiple injection holes (260) are formed in the upper contact portion (230) and the central connecting portion (250). In addition, the lower reinforcing frame (162) may be in the form of a flat plate rather than a bar.

도 13을 참고하면, 본 발명은 프레임 구조체(100)의 후방 프레임(150)이 돌출되며 만곡지게 형성되고 중앙 연결부(250)에 주입홀(260)이 형성된 척추 유합용 임플란트(10)로 실시될 수 있다. 또한 하부 보강 프레임(162)은 바(bar) 형태가 아닌 평판 형태일 수 있다.Referring to Fig. 13, the present invention can be implemented as a spinal fusion implant (10) in which the rear frame (150) of the frame structure (100) is formed to protrude and be curved, and an injection hole (260) is formed in the central connecting portion (250). In addition, the lower reinforcing frame (162) may be in the form of a plate rather than a bar.

도 14를 참고하면, 본 발명은 프레임 구조체(100)의 후방 프레임(150)이 돌출되며 만곡지게 형성되고 주입홀(260)이 다수개로 형성된 척추 유합용 임플란트(10)로 실시될 수 있다. 주입홀(260)은 상부 접촉부(230)와 중앙 연결부(250)에 형성될 수 있다. 또한, 하부 보강 프레임(162)은 바(bar) 형태가 아닌 평판 형태일 수 있다.Referring to FIG. 14, the present invention can be implemented as a spinal fusion implant (10) in which the rear frame (150) of the frame structure (100) is formed to protrude and curve and a plurality of injection holes (260) are formed. The injection holes (260) can be formed in the upper contact portion (230) and the central connecting portion (250). In addition, the lower reinforcing frame (162) can be in the form of a plate rather than a bar.

도 15는 본 발명의 척추 유합용 임플란트가 척추 뼈의 전방에 치우치게 배치된 상태를 도시한 도면, 도 16은 본 발명의 척추 유합용 임플란트가 척추 뼈 사이에 사선 형태로 배치된 상태를 도시한 도면, 도 17은 본 발명의 척추 유합용 임플란트가 척추 뼈 사이에 복수개로 배치된 상태를 도시한 도면이다.FIG. 15 is a drawing showing a state in which the spinal fusion implant of the present invention is positioned in a forward direction of the spinal bones, FIG. 16 is a drawing showing a state in which the spinal fusion implant of the present invention is positioned diagonally between the spinal bones, and FIG. 17 is a drawing showing a state in which the spinal fusion implant of the present invention is positioned in multiple numbers between the spinal bones.

도 15 내지 도 17을 참고하면, 본 발명은 척추 뼈의 구조 및 수술 조건에 따라 여러 형태로 삽입되며 배치될 수 있다.Referring to FIGS. 15 to 17, the present invention can be inserted and placed in various forms depending on the structure of the spinal bone and surgical conditions.

도 15를 참고하면, 본 발명은 척추 뼈의 전방 측에 치우치게 배치되며 이웃하는 척추 뼈를 지지할 수 있다.Referring to FIG. 15, the present invention is arranged to be biased toward the front side of the vertebrae and can support the neighboring vertebrae.

도 16을 참고하면, 본 발명은 삽입 방향과 사선을 이루며 배치되며 이웃하는 척추 뼈를 지지할 수 있다.Referring to FIG. 16, the present invention is arranged diagonally with respect to the insertion direction and can support neighboring vertebrae.

도 17을 참고하면, 본 발명은 척추 뼈 사이에 복수개로 대칭적으로 배치되며, 각각이 하중을 분담하며 이웃하는 척추 뼈를 지지할 수 있다.Referring to FIG. 17, the present invention is symmetrically arranged in a plurality of vertebrae, each of which can share the load and support the neighboring vertebrae.

이상에서 본 바와 같이, 본 발명의 일실시예에 따른 척추 유합용 임플란트(10)는 이웃하는 척추 뼈 사이에 삽입되어 척추 뼈가 유합되도록 할 수 있다. 또한, 본 발명은 생리 식염수에 의해 골이식재가 외부로 유출되지 않도록 함에 따라 척추 뼈 사이의 유합이 빠른 시일 내에 이루어지도록 골 성장을 촉진할 수 있다. 또한, 본 발명은 주변 골 조직의 유합을 용이하게 함과 동시에 척추 뼈를 안정적으로 지지할 수 있다. 또한, 본 발명은 척추 뼈의 구조 및 수술 조건에 따라 골이식재가 용이하게 주입될 수 있는 위치에 주입홀(260)이 형성될 수 있다. 또한, 본 발명은 프레임 구조체(100)가 척추 뼈를 지지함에 따라 척추 뼈의 움직임이나 척추 뼈로부터 전달되는 하중에 의해 다공성 구조체(200)가 파손되는 것을 방지할 수 있다. 또한, 본 발명은 척추 뼈와 접촉하는 다공성 구조체(200)의 접촉면이 거칠게 형성됨에 따라 척추 뼈의 골 성장을 촉진할 수 있다. 또한, 본 발명은 척추 뼈 사이에 삽입된 상태에서 유동되지 않고 견고하게 고정될 수 있다. 또한, 본 발명은 척추가 자연스러운 전만각과 후만각을 이룰 수 있도록 할 수 있다. 또한, 본 발명은 이웃하는 척추 뼈 사이에 용이하게 삽입될 수 있다. 또한, 본 발명은 강도가 보강되는 구조를 가짐에 따라 척추 뼈로 전달되는 하중이 크더라도 이를 안정적으로 지지할 수 있다.As described above, the spinal fusion implant (10) according to an embodiment of the present invention can be inserted between adjacent vertebrae to fuse the vertebrae. In addition, the present invention can promote bone growth so that fusion between the vertebrae can occur quickly by preventing the bone graft material from leaking out due to saline solution. In addition, the present invention can facilitate fusion of surrounding bone tissues while stably supporting the vertebrae. In addition, the present invention can form an injection hole (260) at a location where the bone graft material can be easily injected depending on the structure of the vertebrae and surgical conditions. In addition, the present invention can prevent the porous structure (200) from being damaged by movement of the vertebrae or a load transmitted from the vertebrae as the frame structure (100) supports the vertebrae. In addition, the present invention can promote bone growth of the vertebrae by forming a rough contact surface of the porous structure (200) that comes into contact with the vertebrae. Furthermore, the present invention can be firmly fixed without moving when inserted between vertebrae. Furthermore, the present invention can enable the spine to form natural lordotic and kyphotic angles. Furthermore, the present invention can be easily inserted between adjacent vertebrae. Furthermore, the present invention can stably support even large loads transmitted to the vertebrae due to its reinforced structure.

이상 첨부된 도면을 참조하여 본 발명의 바람직한 실시예를 설명하였지만, 본 명세서에 기재된 실시예와 도면에 도시된 구성은 본 발명의 가장 바람직한 일 실시예에 불과할 뿐이고 본 발명의 기술적 사상을 모두 대변하는 것은 아니므로, 본 출원시점에 있어서 이들을 대체할 수 있는 다양한 균등물과 변형예들이 있을 수 있음을 이해하여야 한다. 그러므로 이상에서 기술한 실시예들은 모든 면에서 예시적인 것이며 한정적인 것이 아닌 것으로서 이해되어야 하고, 본 발명의 범위는 상세한 설명보다는 후술하는 특허청구범위에 의하여 나타내어지며, 특허청구범위의 의미 및 범위 그리고 그 등가 개념으로부터 도출되는 모든 변경 또는 변형된 형태가 본 발명의 범위에 포함되는 것으로 해석되어야 한다.Although the preferred embodiments of the present invention have been described with reference to the attached drawings, the embodiments described in this specification and the configurations illustrated in the drawings are only the most preferred embodiments of the present invention and do not represent all of the technical ideas of the present invention. Therefore, it should be understood that there may be various equivalents and modified examples that can replace them at the time of filing this application. Therefore, the embodiments described above should be understood as illustrative and not restrictive in all respects, and the scope of the present invention is indicated by the claims described below rather than the detailed description, and all changes or modified forms derived from the meaning and scope of the claims and equivalent concepts should be interpreted as being included in the scope of the present invention.

Claims (15)

이웃하는 척추 뼈 사이에 배치되고, 트러스 구조를 형성하며 상기 척추 뼈를 지지하는 프레임 구조체; 및A frame structure positioned between adjacent vertebrae, forming a truss structure and supporting the vertebrae; and 상기 프레임 구조체의 내부 공간의 적어도 일부를 채우며 이웃하는 상기 척추 뼈와 접촉되는 다공성 구조체;를 포함하는 척추 유합용 임플란트.An implant for spinal fusion, comprising a porous structure filling at least a portion of the inner space of the frame structure and in contact with the adjacent vertebrae. 제1항에 있어서,In the first paragraph, 상기 프레임 구조체는The above frame structure 상부 프레임;upper frame; 상기 상부 프레임으로부터 이격되어 배치되는 하부 프레임; 및a lower frame positioned apart from the upper frame; and 상기 상부 프레임과 상기 하부 프레임 사이에 배치되며 절점이 형성되는 웹 프레임;A web frame disposed between the upper frame and the lower frame and having a node formed therein; 을 포함하는 척추 유합용 임플란트.Implants for spinal fusion including: 제2항에 있어서,In the second paragraph, 상기 상부 프레임의 상면과 상기 하부 프레임의 하면에 이웃하는 상기 척추 뼈와 각각 접촉되는 요철부가 돌출 형성되는, 척추 유합용 임플란트. An implant for spinal fusion, in which a protruding portion is formed on the upper surface of the upper frame and the lower surface of the lower frame, respectively, to contact the adjacent spinal bones. 제2항에 있어서,In the second paragraph, 상기 프레임 구조체는 일단부터 상기 척추 뼈 사이로 삽입되며 배치되고,The above frame structure is inserted and placed between the vertebrae from the beginning, 상기 상부 프레임과 상기 하부 프레임은 상기 상부 프레임 및 상기 하부 프레임의 일단 사이의 간격이 타단 사이의 간격보다 크도록 상기 프레임 구조체의 삽입 방향과 경사를 형성하는, 척추 유합용 임플란트.An implant for spinal fusion, wherein the upper frame and the lower frame form an insertion direction and an inclination of the frame structure such that the gap between one end of the upper frame and the lower frame is greater than the gap between the other ends. 제2항에 있어서,In the second paragraph, 상기 프레임 구조체는 The above frame structure 상기 상부 프레임의 일단과 상기 하부 프레임의 일단을 연결하고, 상기 척추 뼈 사이로 삽입되는 방향으로 돌출되며 만곡지게 형성되는 전방 프레임; 및A front frame that connects one end of the upper frame and one end of the lower frame, and is formed to be curved and protrude in a direction inserted between the vertebrae; and 상기 상부 프레임의 타단과 상기 하부 프레임의 타단을 연결하고, 수술기구와 착탈되는 결합부가 형성되는 후방 프레임;A rear frame connecting the other end of the upper frame and the other end of the lower frame, and forming a connecting portion that is detachable from a surgical instrument; 을 더 포함하는 척추 유합용 임플란트.An implant for spinal fusion comprising: 제2항에 있어서,In the second paragraph, 상기 프레임 구조체는 The above frame structure 상기 상부 프레임을 연결하는 상부 보강 프레임; 및an upper reinforcing frame connecting the upper frame; and 상기 하부 프레임을 연결하는 하부 보강 프레임;A lower reinforcing frame connecting the above lower frames; 을 더 포함하는 척추 유합용 임플란트.An implant for spinal fusion comprising: 제1항에 있어서,In the first paragraph, 상기 다공성 구조체는 공극을 형성하도록 소정의 길이와 두께로 서로 연결되는 스트럿을 포함하고,The above porous structure comprises struts connected to each other with a predetermined length and thickness to form a gap, 상기 프레임 구조체의 평균 두께는 상기 스트럿의 평균 두께보다 두꺼운, 척추 유합용 임플란트.An implant for spinal fusion, wherein the average thickness of the frame structure is thicker than the average thickness of the strut. 이웃하는 척추 뼈 사이에 배치되어 상기 척추 뼈를 지지하는 프레임 구조체; 및A frame structure positioned between adjacent vertebrae to support said vertebrae; and 상기 프레임 구조체의 내부 공간의 적어도 일부를 채우며 상기 내부 공간에 주입된 골이식재를 가두는 다공성 구조체; A porous structure that fills at least a portion of the internal space of the frame structure and confines bone graft material injected into the internal space; 를 포함하는 척추 유합용 임플란트.Implants for spinal fusion including. 제8항에 있어서,In paragraph 8, 상기 다공성 구조체는, 소정의 길이와 두께로 서로 연결되는 스트럿을 포함함에 따라 다수의 공극을 형성하는, 척추 유합용 임플란트.An implant for spinal fusion, wherein the porous structure comprises struts interconnected with a predetermined length and thickness, thereby forming a plurality of pores. 제9항에 있어서,In paragraph 9, 상기 다공성 구조체는 상기 프레임 구조체의 상부 상에 배치되는 상부 접촉부와, 상기 프레임 구조체의 하부 상에 배치되는 하부 접촉부와, 상기 상부 접촉부 및 상기 하부 접촉부로부터 연장되는 중앙 연결부로 분획되고,The porous structure is divided into an upper contact portion disposed on the upper part of the frame structure, a lower contact portion disposed on the lower part of the frame structure, and a central connecting portion extending from the upper contact portion and the lower contact portion. 상기 중앙 연결부의 상기 공극의 평균크기는 상기 상부 접촉부 및 상기 하부 접촉부의 상기 공극의 평균크기보다 작은, 척추 유합용 임플란트.An implant for spinal fusion, wherein the average size of the gap of the central connecting portion is smaller than the average size of the gap of the upper contact portion and the lower contact portion. 제10항에 있어서,In Article 10, 상기 상부 접촉부, 상기 하부 접촉부 및 상기 중앙 연결부의 상기 공극의 평균크기는 0.1mm 내지 1.5mm 범위인, 척추 유합용 임플란트.An implant for spinal fusion, wherein the average size of the gaps of the upper contact portion, the lower contact portion, and the central connecting portion is in the range of 0.1 mm to 1.5 mm. 제10항에 있어서,In Article 10, 상기 상부 접촉부, 상기 하부 접촉부 및 상기 중앙 연결부의 공극률은 50% 내지 90% 범위이고, The porosity of the upper contact portion, the lower contact portion, and the central connecting portion is in the range of 50% to 90%, 상기 중앙 연결부는 상기 상부 접촉부 및 상기 하부 접촉부보다 더 큰 공극률을 가지는, 척추 유합용 임플란트.An implant for spinal fusion, wherein the central connecting portion has a greater porosity than the upper contact portion and the lower contact portion. 제10항에 있어서,In Article 10, 상부 접촉부, 상기 하부 접촉부와 상기 중앙 연결부 중 적어도 어느 하나에 상기 골이식재가 주입되는 주입홀이 형성되는, 척추 유합용 임플란트.An implant for spinal fusion, wherein an injection hole for injecting the bone graft material is formed in at least one of the upper contact portion, the lower contact portion, and the central connection portion. 제10항에 있어서,In Article 10, 상기 프레임 구조체의 상부면의 적어도 일부는 상기 상부 접촉부보다 상방으로 돌출되고,At least a portion of the upper surface of the above frame structure protrudes upwards from the upper contact portion, 상기 프레임 구조체의 하부면의 적어도 일부는 상기 하부 접촉부보다 하방으로 돌출되는, 척추 유합용 임플란트. An implant for spinal fusion, wherein at least a portion of the lower surface of the frame structure protrudes downwards from the lower contact portion. 제10항에 있어서,In Article 10, 상기 상부 접촉부 및 상기 하부 접촉부의 표면은 상기 중앙 연결부의 표면보다 더 거친 면을 갖도록 형성되는, 척추 유합용 임플란트.An implant for spinal fusion, wherein the surfaces of the upper contact portion and the lower contact portion are formed to have a rougher surface than the surface of the central connecting portion.
PCT/KR2025/095065 2024-04-16 2025-03-21 Spinal fusion implant Pending WO2025221089A1 (en)

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KR10-2024-0050392 2024-04-16
KR1020240187430A KR20250153088A (en) 2024-04-16 2024-12-16 Spinal Fusion Implant
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US8430930B2 (en) * 2008-12-18 2013-04-30 4-Web, Inc. Truss implant
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KR20190115860A (en) * 2018-04-04 2019-10-14 건양대학교산학협력단 Intervertebral Fusion Implant of Porous Structure with Improved Fixing Part
US10675158B2 (en) * 2015-12-16 2020-06-09 Nuvasive, Inc. Porous spinal fusion implant
KR102385810B1 (en) * 2021-11-26 2022-04-14 알앤엑스(주) Intervertebral body fusion device

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* Cited by examiner, † Cited by third party
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US8430930B2 (en) * 2008-12-18 2013-04-30 4-Web, Inc. Truss implant
US20130158672A1 (en) * 2010-06-18 2013-06-20 4-Web, Inc. Bone implant interface system and method
US10675158B2 (en) * 2015-12-16 2020-06-09 Nuvasive, Inc. Porous spinal fusion implant
KR20190115860A (en) * 2018-04-04 2019-10-14 건양대학교산학협력단 Intervertebral Fusion Implant of Porous Structure with Improved Fixing Part
KR102385810B1 (en) * 2021-11-26 2022-04-14 알앤엑스(주) Intervertebral body fusion device

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