WO2025137309A1

WO2025137309A1 - Oral care compositions

Info

Publication number: WO2025137309A1
Application number: PCT/US2024/061072
Authority: WO
Inventors: Rong Dong; Suman Kumar Chopra; Shuyun Wu
Original assignee: Colgate Palmolive Co
Current assignee: Colgate Palmolive Co
Priority date: 2023-12-19
Filing date: 2024-12-19
Publication date: 2025-06-26
Anticipated expiration: 2026-06-19

Abstract

Aspects of the invention are directed to oral care compositions providing an enhanced level of shine to teeth. In accordance with some aspects, provided is an oral care composition including from about 0.1 to about 20 wt.% of one or more gelling agent comprising a cross linked polyvinylpyrrolidone, an ammonium acryloyldimethyltaurate/VP copolymer, or a combination of two or more thereof; and from about 1 to about 35 wt.% of one or more abrasive comprising an insoluble phosphate, wherein all weight percentages are based on the total weight of the oral care composition.

Description

ORAL CARE COMPOSITIONS

CROSS-REFERENCE TO RELATED APPLICATIONS

[0001] This application claims the benefit of priority from U.S. Provisional Patent Application No. 63/611,890, filed December 19, 2023, titled Oral Care Compositions, which is hereby incorporated herein by reference in its entirety for all purposes.

BACKGROUND

[0002] Oral care compositions, such as dentifrice compositions, can typically include one or more ingredients for maintaining the health of the oral cavity. Consumers have become aware of and desiring oral care compositions that also maintain the aesthetics of their teeth. To address a desire for whiter teeth, consumer product companies have focused on producing toothpastes having a whitening agent.

[0003] Additionally, many toothpastes include an abrasive to debride and physically scrub the external surface of the teeth. This scrubbing action removes the organic film (i.e. the pellicle), formed of salivary proteins which covers the teeth and which is known to become stained and discolored by foods, such as coffee, tea and berries, as well as, by tobacco smoke, cationic antibacterials, and chromogenic bacteria. Such physical removal of the stained pellicle is a simple and effective means of removing the undesirable surface staining and discoloration which occurs daily. Further, such physical removal of the pellicle also removes plaque bacteria on the pellicle surface.

BRIEF SUMMARY

[0004] This summary is intended merely to introduce a simplified summary of some aspects of one or more implementations of the present disclosure. Further areas of applicability of the present disclosure will become apparent from the detailed description provided hereinafter. This summary is not an extensive overview, nor is it intended to identify key or critical elements of the present teachings, nor to delineate the scope of the disclosure. Rather, its purpose is merely to present one or more concepts in simplified form as a prelude to the detailed description below.

[0005] Aspects of the invention are directed to oral care compositions providing an enhanced level of shine to teeth. In accordance with some aspects, provided is an oral care composition including from about 0.1 to about 20 wt.% of one or more gelling agent comprising a cross linked polyvinylpyrrolidone, an ammonium acryloyldimethyltaurate/VP copolymer, or a combination of two or more thereof; and from about 1 to about 35 wt.% of one or more abrasive comprising an insoluble phosphate, wherein all weight percentages are based on the total weight of the oral care composition.

[0006] In accordance with further aspects of the invention, provided is a method for enhancing the shine of a tooth, the method comprising increasing the molar ratio of calcium to carbon on a surface of the tooth using an oral care composition comprising a polymer network formed of at least one of cross linked polyvinylpyrrolidone or ammonium acryloyldimethyltaurate/VP copolymer and insoluble phosphate contained in the polymer network.

[0007] In yet further aspects of the invention, disclosed is a use of a dentifrice for enhancing the shine of a tooth by increasing the molar ratio of calcium to carbon on a surface of the tooth, the oral care composition (e.g., in the form of a dentifrice) comprising a polymer network formed of at least one of cross linked polyvinylpyrrolidone or ammonium acryloyldimethyltaurate/VP copolymer and insoluble phosphate contained in the polymer network.

[0008] A non-limiting list of example embodiments is provided below.

[0009] In accordance with an embodiment 1, provided is an oral care composition comprising: from about 0.1 to about 20 wt.% of one or more gelling agent comprising a cross linked polyvinylpyrrolidone, an ammonium acryloyldimethyltaurate/VP copolymer, or a combination of two or more thereof; and from about 1 to about 35 wt.% of one or more abrasive comprising an insoluble phosphate, wherein all weight percentages are based on the total weight of the oral care composition.

[0010] In accordance with an embodiment 2, provided is the oral care composition according to embodiment 1 comprising a polymer network formed from at least the one or more gelling agent. [0011] In accordance with an embodiment 3, provided is the oral care composition according to embodiment 2, wherein the polymer network consists essentially of the one or more gelling agent. [0012] In accordance with an embodiment 4, provided is the oral care composition according to embodiment 2 or embodiment 3, wherein polymer network contains the insoluble phosphate therein.

[0013] In accordance with an embodiment 5, provided is the oral care composition according to embodiment 4, wherein the polymer network is bonded to the insoluble phosphate therein. [0014] In accordance with an embodiment 6, provided is the oral care composition according to any of embodiment 2 to embodiment 5, wherein the polymer network comprises a plurality of clusters formed of the insoluble phosphate.

[0015] In accordance with an embodiment 7, provided is the oral care composition according to any foregoing embodiment, wherein the insoluble phosphate is an insoluble phosphate salt selected from calcium pyrophosphate, dicalcium orthophosphate dihydrate, tricalcium phosphate, and calcium polymetaphosphate, and a combination of two or more thereof.

[0016] In accordance with an embodiment 8, provided is the oral care composition according to any foregoing embodiment, wherein the one or more abrasive comprises calcium pyrophosphate. [0017] In accordance with an embodiment 9, provided is the oral care composition according to any foregoing embodiment, wherein the oral care composition comprises about 10 wt.% or more of water, optionally from about 30 wt.% to about 55 wt.% of water.

[0018] In accordance with an embodiment 10, provided is the oral care composition according to any foregoing embodiment, wherein the oral care composition has about 7 wt.% or less of natural polymers.

[0019] In accordance with an embodiment 11, provided is the oral care composition according to any foregoing embodiment, wherein the oral care composition has a total amount of all polymers of about 7 wt.% or less.

[0020] In accordance with an embodiment 12, provided is the oral care composition according to any foregoing embodiment further comprising: a polyol, optionally, in an amount from about 5 to about 63 wt.%.

[0021] In accordance with an embodiment 13, provided is the oral care composition according to embodiment 11, wherein the polyol is selected from ethylene glycol, propylene glycol, butylene glycol, hexylene glycol, glycerin, diglycerin, diethylene glycol, dipropylene glycol, triethylene glycol, tetraethylene glycol, pentaethylene glycol, dipropylene glycol, 2 -butene- 1,4-diol, 2-ethyl- 1,3-hexanediol, 2-methyl-2,4-pentanediol, caprylyl glycol, 1,2-hexanediol, 1,2-pentanediol, and 4-m ethyl- 1,2-pentanediol, and a combination of two or more thereof.

[0022] In accordance with an embodiment 14, provided is the oral care composition according to any foregoing embodiment, wherein the one or more gelling agent comprises from about 0.3 to about 5 wt.%, preferably about 0.3 to about 4 wt.%, about 0.3 to about 3 wt.%, or about 0.3 to about 2.5 wt.%, of acryloyl dimethyltaurate/VP copolymer. [0023] In accordance with an embodiment 15, provided is the oral care composition according to any foregoing embodiment, wherein the one or more gelling agent comprises from about 0.3 to about 6 wt.%, preferably about 0.3 to about 5 wt.%, about 0.3 to about 4 wt.%, or about 0.3 to about 3 wt.% of a sodium polyacryloyldimethyltaurate.

[0024] In accordance with an embodiment 16, provided is the oral care composition according to any foregoing embodiment further comprising: an anti-calculus agent, optionally, in an amount from about 0.5 to about 10 wt.%.

[0025] In accordance with an embodiment 17, provided is the oral care composition according to embodiment 16, wherein the anti -cal cuius agent is selected from tetrasodium pyrophosphate, ammonium tripolyphosphate, hexametaphosphate salt, polycarboxylate polymers, polyvinyl methyl ether/maleic anhydride (PVME/MA) copolymers, and a combination of two or more thereof.

[0026] In accordance with an embodiment 18, provided is the oral care composition according to any foregoing embodiment further comprising: a fluoride source, optionally, in an amount from about 0.1 to about 2 wt.%.

[0027] In accordance with an embodiment 19, provided is the oral care composition according to embodiment 18, wherein the fluoride source is selected from stannous fluoride, sodium fluoride, potassium fluoride, sodium monofluorophosphate, sodium fluorosilicate, ammonium fluorosilicate, amine fluoride, ammonium fluoride, and a combination of two or more thereof.

[0028] In accordance with an embodiment 20, provided is the oral care composition according to any foregoing embodiment further comprising: an anionic surfactant, optionally, in an amount from about 0.5 to about 10 wt.%.

[0029] In accordance with an embodiment 21, provided is the oral care composition according to embodiment 20, wherein the anionic surfactant is selected from ammonium lauryl sulfate, ammonium lauryl ether sulfate, sodium dodecyl sulfate, sodium coco-sulfate, ammonium coco- sulfate, sodium lauryl sulfate, sodium lauryl ether sulfate, and a combination of two or more thereof.

[0030] In accordance with an embodiment 22, provided is the oral care composition according to any foregoing embodiment further comprising potassium nitrate. [0031] In accordance with an embodiment 23, provided is the oral care composition according to embodiment 20, wherein the potassium nitrate is present in an amount from about 0.1 to about 9 wt.%.

[0032] In accordance with an embodiment 24, provided is the oral care composition according to any foregoing embodiment further comprising a whitening agent.

[0033] In accordance with an embodiment 25, provided is the oral care composition according to embodiment 24, wherein the peroxide is selected from hydrogen peroxide, lithium peroxide, potassium peroxide, sodium peroxide, magnesium peroxide, calcium peroxide, barium peroxide, alkyl hydrogen peroxides, dialkyl peroxides, alkyl peroxy acids, peroxy esters, diacyl peroxides, benzoyl peroxide, monoperoxyphthalate, and a combination of two or more thereof.

[0034] In accordance with an embodiment 26, provided is a method for enhancing the shine of a tooth, the method comprising: increasing the molar ratio of calcium to carbon on a surface of the tooth using an oral care composition comprising a polymer network formed of at least one of cross linked polyvinylpyrrolidone or ammonium acryloyldimethyltaurate/VP copolymer and insoluble phosphate contained in the polymer network.

[0035] In accordance with an embodiment 27, provided is a use of a dentifrice for enhancing the shine of a tooth by increasing the molar ratio of calcium to carbon on a surface of the tooth, the dentifrice comprising a polymer network formed of at least one of cross linked polyvinylpyrrolidone or ammonium acryloyldimethyltaurate/VP copolymer and insoluble phosphate contained in the polymer network.

[0036] In accordance with an embodiment 28, provided is an oral care composition comprising: from about 0.1 to about 20 wt.% of one or more gelling agent comprising a cross linked polyvinylpyrrolidone, an ammonium acryloyldimethyltaurate/VP copolymer, or a combination of two or more thereof; and from about 1 to about 35 wt.% of one or more abrasive, wherein all weight percentages are based on the total weight of the oral care composition.

[0037] In accordance with an embodiment 29, provided is the oral care composition according to embodiment 28, wherein the one or more abrasive comprises a silica abrasive.

[0038] In accordance with an embodiment 30, provided is an oral care composition comprising: a polymer network formed from about 0.1 to about 20 wt.% of one or more gelling agent and a fumed silica; and from about 1 to about 35 wt.% of one or more abrasive, wherein all weight percentages are based on the total weight of the oral care composition. [0039] In accordance with an embodiment 31 , provided is the oral care composition according to embodiment 30, wherein the one or more gelling agents and the fume silica are present in a weight ratio of about 4: 1 to about 1 :3.

[0040] In accordance with an embodiment 32, provided is the oral care composition according to embodiment 30 or embodiment 31, wherein the one or more gelling agent are selected from a lightly cross-linked polyvinylpyrrolidone, a lightly-crosslinked polyacrylic acid, a lightly crosslinked PVP/PAA, an ammonium acryloyldimethyltaurate/VP copolymer, a crosspolymer-6, a fibril cellulose, and a combination of two or more thereof.

[0041] In accordance with an embodiment 33, provided is the oral care composition according to any one of embodiment 30 to embodiment 32, wherein the one or more abrasive comprises silica abrasive, silicate, aluminosilicates, bentonite, zeolite, kaolin, mica, siliceous or diatomaceous earth, pumice, calcium compounds, calcium carbonate, cuttlebone, polycarbonate, silicon carbide, boron carbide, microcrystalline wax, microcrystalline cellulose, dicalcium phosphate, calcium pyrophosphate, dicalcium orthophosphate dihydrate, tricalcium phosphate, calcium polymetaphosphate, calcium carbonate, calcium bicarbonate, or a combination of two or more thereof.

[0042] In accordance with an embodiment 34, provided is the oral care composition according to any one of embodiment 30 to embodiment 33, wherein the one or more abrasive is selected from dicalcium phosphate, calcium pyrophosphate, dicalcium orthophosphate dihydrate, tricalcium phosphate, calcium polymetaphosphate, calcium carbonate, calcium bicarbonate, and a combination of two or more thereof.

DETAILED DESCRIPTION

[0043] For illustrative purposes, the principles of the present invention are described by referencing various exemplary embodiments thereof. Although certain embodiments of the invention are specifically described herein, one of ordinary skill in the art will readily recognize that the same principles are equally applicable to, and can be employed in other compositions and methods. Before explaining the disclosed embodiments of the present invention in detail, it is to be understood that the invention is not limited in its application to the details of any particular embodiment disclosed herein. The terminology used herein is for the purpose of description and not of limitation. [0044] As used herein and in the appended claims, the singular forms “a”, “an”, and “the” include plural references unless the context dictates otherwise. The singular form of any class of the ingredients refers not only to one chemical species within that class, but also to a mixture of those chemical species. The terms “a” (or “an”), “one or more” and “at least one” may be used interchangeably herein. The terms “comprising”, “including”, and “having” may be used interchangeably. The term “include” should be interpreted as “include, but are not limited to”. The term “including” should be interpreted as “including, but are not limited to”.

[0045] As used throughout, ranges are used as shorthand for describing each and every value that is within the range. Any value within the range can be selected as the terminus of the range. Thus, a range from 1-5, includes specifically 1, 2, 3, 4 and 5, as well as subranges such as 2-5, 3-5, 2-3, 2-4, 1-4, etc.

[0046] The term “about” when referring to a number means any number within a range of 10% of the number. For example, the phrase “about 2 wt.%” refers to a number between and including 1.8 wt.% and 2.2 wt.%.

[0047] All references cited herein are hereby incorporated by reference in their entireties. In the event of a conflict in a definition in the present disclosure and that of a cited reference, the present disclosure controls.

[0048] The abbreviations and symbols as used herein, unless indicated otherwise, take their ordinary meaning. The abbreviation “wt.%” means percent by weight with respect to the oral care composition. The symbol “°” refers to a degree, such as a temperature degree or a degree of an angle. The symbols “h”, “min”, “mb”, “nm”, and “pm” refer to hour, minute, milliliter, nanometer, and micrometer, respectively. The abbreviation “UV-VIS” referring to a spectrometer or spectroscopy, means Ultraviolet-Visible. The abbreviation “rpm” means revolutions per minute.

[0049] When referring to chemical structures, and names, the symbols “C”, “H”, and “O” mean carbon, hydrogen, and oxygen, respectively. The symbols

“=” and “=” mean single bond, double bond, and triple bond, respectively.

[0050] “Volatile”, as used herein, means having a flash point of less than about 100° C. “Nonvolatile”, as used herein, means having a flash point of greater than about 100° C.

[0051] Any member in a list of species that are used to exemplify or define a genus, may be mutually different from, or overlapping with, or a subset of, or equivalent to, or nearly the same as, or identical to, any other member of the list of species. Further, unless explicitly stated, such as when reciting a Markush group, the list of species that define or exemplify the genus is open, and it is given that other species may exist that define or exemplify the genus just as well as, or better than, any other species listed.

[0052] The phrases, “a mixture thereof,” “a combination thereof,” or a combination of two or more thereof’ do not require that the mixture include all of A, B, C, D, E, and F (although all of A, B,

C, D, E, and F may be included). Rather, it indicates that a mixture of any two or more of A, B, C,

D, E, and F can be included. In other words, it is equivalent to the phrase “one or more elements selected from the group consisting of A, B, C, D, E, F, and a mixture of any two or more of A, B, C, D, E, and F ” Likewise, the term “a salt thereof’ also relates to “salts thereof.” Thus, where the disclosure refers to “an element selected from the group consisting of A, B, C, D, E, F, a salt thereof, and a mixture thereof,” it indicates that that one or more of A, B, C, D, and F may be included, one or more of a salt of A, a salt of B, a salt of C, a salt of D, a salt of E, and a salt of F may be included, or a mixture of any two of A, B, C, D, E, F, a salt of A, a salt of B, a salt of C, a salt of D, a salt of E, and a salt of F may be included.

[0053] All components and elements positively set forth in this disclosure can be negatively excluded from the claims. In other words, the oral care compositions of the instant disclosure can be free or essentially free of all components and elements positively recited throughout the instant disclosure. In some instances, the oral care compositions of the present disclosure may be substantially free of non-incidental amounts of the ingredient(s) or compound(s) described herein. A non-inci dental amount of an ingredient or compound is the amount of that ingredient or compound that is added into the oral care composition by itself. For example, an oral care composition may be substantially free of a non-incidental amount of an ingredient or compound, although such ingredient(s) or compound(s) may be present as part of a raw material that is included as a blend of two or more compounds.

[0054] Some of the various categories of components identified may overlap. In such cases where overlap may exist and the oral care composition includes both components (or the composition includes more than two components that overlap), an overlapping compound does not represent more than one component. For example, certain compounds may be characterized as both a fluoride ion source and a stannous ion source. If a particular claim to an oral care composition includes both a polyol and a humectant, glycerin will serve only as either a polyol or a humectant — not both. [0055] For readability purposes, the chemical functional groups are in their adjective form; for each of the adjectives, the word “group” is assumed. For example, the adjective “alkyl” without a noun thereafter, should be read as “an alkyl group.”

[0056] Aspects of the invention are directed to oral care compositions and, preferably, oral care compositions providing an enhanced amount of shine to teeth. The inventors unexpectedly discovered that certain oral care compositions comprising a polymer network comprising certain gelling agents and an insoluble phosphate contained in the polymer network can provide enhanced amounts of shine to teeth. Without being limited to any particular theory, it is believed that oral care compositions having too much or too little gelling agents and/or polymers in the polymer network may adversely affect the oral care compositions ability to polish teeth.

[0057] In accordance with some aspects, provided is an oral care composition including from about 0.1 to about 20 wt.% of one or more gelling agent comprising a cross linked polyvinylpyrrolidone, an ammonium acryloyldimethyltaurate/VP copolymer, or a combination of two or more thereof; and from about 1 to about 35 wt.% of one or more abrasive comprising an insoluble phosphate, wherein all weight percentages are based on the total weight of the oral care composition.

[0058] In accordance with further aspects of the invention, provided is a method for enhancing the shine of a tooth, the method comprising increasing the molar ratio of calcium to carbon on a surface of the tooth using an oral care composition comprising a polymer network formed of at least one of cross linked polyvinylpyrrolidone or ammonium acryloyldimethyltaurate/VP copolymer and insoluble phosphate contained in the polymer network.

[0059] In yet further aspects of the invention, disclosed is a use of a dentifrice for enhancing the shine of a tooth by increasing the molar ratio of calcium to carbon on a surface of the tooth, the oral care composition comprising a polymer network formed of at least one of cross linked polyvinylpyrrolidone or ammonium acryloyldimethyltaurate/VP copolymer and insoluble phosphate contained in the polymer network.

[0060] The oral care compositions may preferably increase the molar ratio of calcium to carbon on a surface of the tooth by at least 500%, preferably by about 1000% or more, about 1250% or more about 1500% or more, about 1750% or more about 2000% or more. In some embodiments, the molar ratio of calcium to carbon on a surface of the tooth is increased by one of the foregoing amounts after brushing the tooth with about 0.3 grams of an oral care composition disclosed herein. [0061] Preferably, the oral care compositions have an enamel polishing potential of about 35% or more. In some preferred embodiments, the oral care composition has an enamel polishing potential of about 38% or more, about 40% or more, about 42% or more, about 46% or more, or about 50% or more. The enamel polish potential may be determined using a Novo-Curve Glossmeter by determining an initial polish score of an enamel substrate (e.g., a bovine tooth) and a post-brushing with the oral care composition polish score of the same enamel substrate, whereby the difference in polishing scores represents the enamel polishing potential.

[0062] Preferably, the oral care composition forms a slurry when combined with water in a weight ratio of the oral care composition to water of 1 :1, whereby the slurry has a viscosity of about 10,000 cP or more, e.g., measured at room temperature (e.g., 20 °C) using a Brookfield viscometer and a spindle number 74 at a spindle rotation of 1 rpm. For example, in certain preferred embodiments, a slurry formed of the oral care composition and water in a weight ratio of the oral care composition to water of 1 :1 has a viscosity of about 12,000 cP or more, about 19,000 cP or more, about 22,000 cP or more, about 34,000 cP or more, about 46,000 cP or more, about 58,000 cP or more, about 68,000 cP or more, about 84,000 cP or more, about 103,000 cP or more, or about 130,000 cP or more, e.g., measured at room temperature (e.g., 20 °C) using a Brookfield viscometer and a spindle number 74 at a spindle rotation of 1 rpm.

[0063] The oral care composition may be formulated to have about 7 wt.% or less of polymers selected from natural polymers, including gums and/or polysaccharides, and non-natural polymers, including acrylates, a polyitaconates, and/or acrylamides, and combinations of two or more thereof. For instance, in some embodiments, the oral care composition has about 7 wt.% or less of non-natural polymers, including acrylates, a polyitaconates, and/or acrylamides, based on the total weight of the oral care composition. In some embodiments, the total amount of non-natural polymers present in the oral care composition is about 6 wt.% or less, have about 5 wt.% or less, about 4 wt.% or less, about 3 wt.% or less, about 2 wt.% or less, about 1 wt.% or less, about 0.5 wt.% or less, based on the total weight of the oral care composition.

[0064] In other embodiments, the oral care composition has about 7 wt.% or less of natural polymers, including gums and polysaccharides, based on the total weight of the oral care composition. For example, the total amount of natural polymers present in the oral care composition may be about 6 wt.% or less, have about 5 wt.% or less, about 4 wt.% or less, about 3 wt.% or less, about 2 wt.% or less, about 1 wt.% or less, about 0.5 wt.% or less, based on the total weight of the oral care composition.

[0065] The oral care compositions may be formulated to have a total amount of all polymers of about 7 wt.% or less, based on the total weight of the oral care composition. For example, the total amount of all polymers present in the oral care composition may have about 6 wt.% or less, have about 5 wt.% or less, about 4 wt.% or less, about 3 wt.% or less, about 2 wt.% or less, about 1 wt.% or less, about 0.5 wt.% or less, based on the total weight of the oral care composition.

[0066] Additionally or alternatively, the oral care composition may be formulated to have a total amount of thickening agents of about 7 wt.% or less, based on the total weight of the oral care composition. For example, the total amount of all polymers present in the oral care composition may have about 6 wt.% or less, have about 5 wt.% or less, about 4 wt.% or less, about 3 wt.% or less, about 2 wt.% or less, about 1 wt.% or less, about 0.5 wt.% or less, based on the total weight of the oral care composition.

[0067] The oral care compositions may be in the form of a dentifrice, a toothpaste, a gel, and/or the like. Suitable components, such as those listed below, may be included or excluded from the formulations for the oral care compositions disclosed herein depending on the specific combination of other ingredients and/or the form of the oral care compositions. Additionally or alternatively, the oral care compositions may in some embodiments have a single phase, which contains that components and/or ingredients of the oral care composition. In other embodiments, the oral care composition may include two or more phases, such as two, three, four, or five phases. [0068] The oral care compositions typically comprise one or more gelling agent(s). The one or more gelling agent(s) may be present in the oral care composition in an amount from about 0. 1 to about 7 wt.%, based on the total weight of the oral care composition. In some embodiments, the gelling agent(s) are present in the oral care composition in an amount from about 0.1 to about 7 wt.%, about 0. 1 to about 5 wt.%, about 0. 1 to about 4 wt.%, about 0.1 to about 3 wt.%, about 0. 1 to about 2 wt.%; from about 0.5 to about 7 wt.%, about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%; from about 1 to about 7 wt.%, about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; from about 2 to about 7 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%; from about 3 to about 7 wt.%, about 3 to about 5 wt.%, about 3 to about 4 wt.%; from about 4 to about 7 wt.%, about 4 to about 5 wt.%, from about 5 to about 7 wt.%, about 5 to about 6 wt.%, or any range or subrange thereof, based on the total weight of the oral care composition.

[0069] Preferably, the one or more gelling agent(s) comprises a cross linked polyvinylpyrrolidone, an ammonium acryloyldimethyltaurate/VP copolymer, or a combination of two or more thereof. In some embodiments, the oral care composition includes one or more gelling agents consisting of a cross linked polyvinylpyrrolidone, an ammonium acryloyldimethyltaurate/VP copolymer, or a combination of two or more thereof. The cross linked polyvinylpyrrolidone is preferably a lightly cross-linked polyvinylpyrrolidone. In certain preferred embodiments, the one or more gelling agent(s) consists of lightly-crosslinked polymers, such as those chosen from lightly cross-linked polyvinylpyrrolidone (PVP), lightly-crosslinked polyacrylic acid (PAA), lightly cross-linked PVP/PAA, ammonium acryloyldimethyltaurate/VP copolymer, crosspolymer-6, and/or fibril cellulose. In at least one embodiment, the one or more gelling agent(s) consists of those selected from lightly cross-linked polyvinylpyrrolidone (PVP), lightly-crosslinked polyacrylic acid (PAA), lightly cross-linked PVP/PAA, ammonium acryloyldimethyltaurate/VP copolymer, crosspolymer- 6, fibril cellulose, and a combination of two or more thereof.

[0070] The ammonium acryloyldimethyltaurate/VP copolymer and/or the cross linked polyvinylpyrrolidone may be chosen from those having a molecular weight of from about 100,000 to about 10,000,000 g/mol. For example, the ammonium acryloyldimethyltaurate/VP copolymer and/or the cross linked polyvinylpyrrolidone may have a molecular weight of about 100,000 to about 10,000,000 g/mol, about 100,000 to about 8,000,000 g/mol, about 100,000 to about 6,000,000 g/mol, about 100,000 to about 4,000,000 g/mol, about 100,000 to about 2,000,000 g/mol, about 100,000 to about 1,000,000 g/mol; from about 250,000 to about 10,000,000 g/mol, about 250,000 to about 8,000,000 g/mol, about 250,000 to about 6,000,000 g/mol, about 250,000 to about 4,000,000 g/mol, about 250,000 to about 2,000,000 g/mol, about 250,000 to about 1,000,000 g/mol; from about 500,000 to about 10,000,000 g/mol, about 500,000 to about 8,000,000 g/mol, about 500,000 to about 6,000,000 g/mol, about 500,000 to about 4,000,000 g/mol, about 500,000 to about 2,000,000 g/mol, about 500,000 to about 1,000,000 g/mol; from about 1,000,000 to about 10,000,000 g/mol, about 1,000,000 to about 8,000,000 g/mol, about 1,000,000 to about 6,000,000 g/mol, about 1,000,000 to about 4,000,000 g/mol, about 1,000,000 to about 2,000,000 g/mol; from about 2,000,000 to about 10,000,000 g/mol, about 2,000,000 to about 8,000,000 g/mol, about 2,000,000 to about 6,000,000 g/mol, about 2,000,000 to about 4,000,000 g/mol; from about 4,000,000 to about 10,000,000 g/mol, about 4,000,000 to about 8,000,000 g/mol, about 4,000,000 to about 6,000,000 g/mol; from about 6,000,000 to about 10,000,000 g/mol, about 6,000,000 to about 8,000,000 g/mol, or any range or subrange thereof. [0071] In certain preferred embodiments, the oral care composition comprises a polymer network. The polymer network may be formed predominantly of or solely of gelling agents. In certain preferred embodiments, the polymer network is formed of gelling agents and a fumed silica. Preferably, the polymer network preferably is formed of at least one gelling agent selected from a cross linked polyvinylpyrrolidone, ammonium acryloyldimethyltaurate/VP copolymer, or a combination of two or more thereof. The polymer network may be formed substantially of or solely of one or more polymer selected from a cross linked polyvinylpyrrolidone, an ammonium acryloyldimethyltaurate/VP copolymer, optionally trace materials, or a combination of two or more thereof. For instance, the polymer network may consist essentially of one or more gelling agents selected from a cross linked polyvinylpyrrolidone, ammonium acryloyldimethyltaurate/VP copolymer, or a combination of two or more thereof. In at least one embodiment, the polymer network may consists of one or more gelling agents selected from a cross linked polyvinylpyrrolidone, ammonium acryloyldimethyltaurate/VP copolymer, or a combination of two or more thereof.

[0072] The polymer network may preferably contain an insoluble phosphate therein. The insoluble polyphosphate may be releasably contained within the polymer network. For instance, the polymer network may release the abrasive upon an amount of shear, such as the amount of shear associated with brushing teeth. In some embodiments, the polymer network is bonded to the insoluble phosphate. In certain embodiments, the polymer network exhibits Vander Waals forces on the insoluble phosphate. Additionally or alternatively, the insoluble phosphate may be in the form of clusters in the polymer matrix. For example, in some embodiments, the polymer matrix includes a plurality of clusters formed of the insoluble phosphate in such polymer matrix.

[0073] In certain preferred embodiments, the oral care composition may have a polymer network formed from one or more of the gelling agent(s), preferably those disclosed herein, and a fumed silica. Without being limited to any particular theory, it is believed that particular polymer networks formed from certain gelling agent(s) (such as those disclosed herein) and fumed silica can capture certain abrasive(s) (such as insoluble phosphates and/or calcium-based abrasives) and enhance the polishing efficiency of abrasive and the oral care composition as a whole. FIG. 1 provides an SEM image of a polymer network and calcium pyrophosphate abrasive, which is bonded to the polymer network.

[0074] The polymer network may be formed from one or more gelling agents and a fumed silica, where the total amount of one or more gelling agents and the total amount of fumed silica is present in a weight ratio of the gelling agents to the fumed silica of about 4:1 to about 1 :3, about 4:1 to about 1 :2, about 4: 1 to about 1 : 1; from about 3 : 1 to about 1 :3, about 3 : 1 to about 1 :2, about 3 : 1 to about 1 : 1; from about 2:1 to about 1 :3, about 2: 1 to about 1 :2, about 2: 1 to about 1:1, or any range or subrange thereof.

[0075] The oral care compositions may include one or more additional thickening agent other than the cross linked polyvinylpyrrolidone and/or the ammonium acryloyldimethyltaurate/VP copolymer. In certain embodiments, the polymer network may comprise of one or more additional thickening agents other than the cross linked polyvinylpyrrolidone and/or the ammonium acryloyldimethyltaurate/VP copolymer. The one or more additional thickening agents may be selected from, e.g., polysaccharides, acrylates, polymers, polyitaconates, acrylamides, and combinations of two or more thereof. Examples of polysaccharides that may be included or in some embodiments excluded from the oral care composition include: cellulose, carboxymethyl hydroxyethylcellulose, cellulose acetate propionate carboxylate, hydroxyethylcellulose, hydroxyethyl ethylcellulose, hydroxypropylcellulose, hydroxypropyl methylcellulose, methyl hydroxyethylcellulose, microcrystalline cellulose, sodium cellulose sulfate, carrageenan, xanthan gum, or a combination of two more thereof.

[0076] Examples of acrylates that are worth mentioning include, e.g., isobutyl acrylate, tert-butyl acrylate, 2-ethylhexyl acrylate, lauryl acrylate, lauryl/tridecyl acrylate, cetyl acrylate, stearyl acrylate, cyclohexyl acrylate, benzyl acrylate, isobornyl acrylate, 2-methoxyethyl acrylate, 2- ethoxyethyl acrylate, 2-ethoxyethoxyethyl acrylate, 2-phenoxyethyl acrylate, tetrahydrofurfuryl acrylate, 2-hydroxyethyl acrylate, 2-hydroxypropyl acrylate, 4-hydroxybutyl acrylate, dimethylaminoethyl acrylate, 1,4-butanediol acrylate, or a combination of two or more thereof.

[0077] The acrylate may be chosen from diacrylates. In some embodiments, the oral care composition includes a diacrylate chosen from 1,4-butanediol, 1,6-hexanediol, tetraethylene glycol, tripropylene glycol, ethoxylated bisphenol-A, and a combination of two or more thereof. Triacrylate monomers include trimethylol propane, ethoxylated, glyceryl propoxy, and pentaerythritol. [0078] Acrylates further include methacrylates, such as methyl methacrylate, ethyl methacrylate, n-butyl methacrylate, isobutyl methacrylate, tert-butyl methacrylate, 2-ethylhexyl methacrylate, lauryl methacrylate, alkyl methacrylate, tridecyl methacrylate, stearyl methacrylate, cyclohexyl methacrylate, benzyl methacrylate, isobornyl methacrylate, 2-hydroxyethyl methacrylate, 2- hydroxypropyl methacrylate, dimethylaminoethyl methacrylate, diethylaminoethyl methacrylate, glycidyl methacrylate, tetrahydrofurfuryl methacrylate, allyl methacrylate, ethylene glycol methacrylate, triethylene glycol methacrylate, tetraethylene glycol methacrylate, 1,3- butyleneglycol methacrylate, 1,6-hexanediol methacrylate, trimethylopropane methacrylate, ethoxy ethyl methacrylate, trifluoroethyl methacrylate, or a combination of two or more thereof. In certain embodiments, the oral care composition may be free of one or more of the foregoing acrylates.

[0079] Examples of acrylamides include, but are not limited to, acrylamide, methacrylamide and di(Ci-C3o) alkyl-acrylamides and -methacrylamides such as those of methyl, ethyl, propyl, butyl, pentyl, hexyl and the like. N-substituted acrylamides that may be suitable include N- ethylacrylamide, N-tert-butyl acrylamide, N-tert-octylacrylamide, N-octyl acrylamide, N- decyl acrylamide, N-dodecylacrylamide and the corresponding N-substituted methacrylamides. Other N-substituted acrylamides include N-hydroxymethyl acrylamide, N-isopropylacrylamide, N-methylacrylamide, N,N' -methylenebisacrylamide, N-isobutoxymethylacrylamide, N,N- dimethylacrylamide, 2-acrylamido-2-methylpropanesulfonic acid, or a combination of two or more thereof. In certain embodiments, the oral care composition may be free of one or more of the foregoing acrylamides.

[0080] The additional thickening agents other than the cross linked polyvinylpyrrolidone and/or the ammonium acryloyldimethyltaurate/VP copolymer may be present in an amount from about 0.1 to about 7 wt.%, about 0.1 to about 5 wt.%, about 0.1 to about 4 wt.%, about 0.1 to about 3 wt.%, about 0. 1 to about 2 wt.%; from about 0.5 to about 7 wt.%, about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%; from about 1 to about 7 wt.%, about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; from about 2 to about 7 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%; from about 3 to about 7 wt.%, about 3 to about 5 wt.%, about 3 to about 4 wt.%; from about 4 to about 7 wt.%, about 4 to about 5 wt.%, from about 5 to about 7 wt.%, about 5 to about 6 wt.%, or any range or subrange thereof, based on the total weight of the oral care composition.

[0081] In some embodiments, the additional thickening agent comprises sodium acryloyldimethyltaurate. Sodium acryloyldimethyltaurate, as used herein, includes sodium polyacryloyldimethyltaurate. The sodium acryloyldimethyltaurate may be chosen from those having a molecular weight of from about 100,000 to about 10,000,000 g/mol. For example, the thickening system may comprise a sodium acryloyldimethyltaurate having a molecular weight of about 100,000 to about 10,000,000 g/mol, about 100,000 to about 8,000,000 g/mol, about 100,000 to about 6,000,000 g/mol, about 100,000 to about 4,000,000 g/mol, about 100,000 to about 2,000,000 g/mol, about 100,000 to about 1,000,000 g/mol; from about 250,000 to about 10,000,000 g/mol, about 250,000 to about 8,000,000 g/mol, about 250,000 to about 6,000,000 g/mol, about 250,000 to about 4,000,000 g/mol, about 250,000 to about 2,000,000 g/mol, about 250,000 to about 1,000,000 g/mol; from about 500,000 to about 10,000,000 g/mol, about 500,000 to about 8,000,000 g/mol, about 500,000 to about 6,000,000 g/mol, about 500,000 to about 4,000,000 g/mol, about 500,000 to about 2,000,000 g/mol, about 500,000 to about 1,000,000 g/mol; from about 1,000,000 to about 10,000,000 g/mol, about 1,000,000 to about 8,000,000 g/mol, about 1,000,000 to about 6,000,000 g/mol, about 1,000,000 to about 4,000,000 g/mol, about 1,000,000 to about 2,000,000 g/mol; from about 2,000,000 to about 10,000,000 g/mol, about 2,000,000 to about 8,000,000 g/mol, about 2,000,000 to about 6,000,000 g/mol, about 2,000,000 to about 4,000,000 g/mol; from about 4,000,000 to about 10,000,000 g/mol, about 4,000,000 to about 8,000,000 g/mol, about 4,000,000 to about 6,000,000 g/mol; from about 6,000,000 to about 10,000,000 g/mol, about 6,000,000 to about 8,000,000 g/mol, or any range or subrange thereof.

[0082] The gelling agent may, in some instances, be selected from cross-linked polyacrylic acid and/or a salt thereof, such as branched polyacrylic acids and/or salts thereof. In further instances, however, the oral care composition includes at least one linear polyacrylic acid and/or a salt thereof. The cross-linked polyacrylic acid and/or a salt thereof may be a carbomer. The carbomer may be selected from Carbopols. For instance, the personal care composition may include, or in some cases exclude, a polyacrylic acid and/or a salt thereof selected from Carbopol 2984, Carbopol 934, Carbopol Ultrez 10, Carbopol 940, Carbopol 941, Carbopol 956 Carbopol 981, Carbopol 2020, and a combination of two or more thereof. Additionally or alternatively, the cross-linked polyacrylic acid and/or a salt thereof may be selected from carbomers. [0083] The oral care composition typically includes one or more abrasive, e.g., in an amount from about 1 to about 35 wt.%, based on the total weight of the oral care composition. In some instances, the total amount of abrasive(s) present in the oral care composition is from about 1 to about 35 wt.%, about 1 to about 35 wt.%, about 1 to about 31 wt.%, about 1 to about 27 wt.%, about 1 to about 23 wt.%, about 1 to about 19 wt.%, about 1 to about 17 wt.%, about 1 to about 15 wt.%, about 1 to about 13 wt.%; from about 4 to about 35 wt.%, about 4 to about 35 wt.%, about 4 to about 31 wt.%, about 4 to about 27 wt.%, about 4 to about 23 wt.%, about 4 to about 19 wt.%, about 4 to about 17 wt.%, about 4 to about 15 wt.%, about 4 to about 13 wt.%; from about 7 to about 35 wt.%, about 7 to about 35 wt.%, about 7 to about 31 wt.%, about 7 to about 27 wt.%, about 7 to about 23 wt.%, about 7 to about 19 wt.%, about 7 to about 17 wt.%, about 7 to about 15 wt.%, about 7 to about 13 wt.%; from about 10 to about 35 wt.%, about 10 to about 35 wt.%, about 10 to about 31 wt.%, about 10 to about 27 wt.%, about 10 to about 23 wt.%, about 10 to about 19 wt.%, about 10 to about 17 wt.%, about 10 to about 15 wt.%; from about 13 to about 35 wt.%, about 13 to about 35 wt.%, about 13 to about 31 wt.%, about 13 to about 27 wt.%, about 13 to about 23 wt.%, about 13 to about 19 wt.%, about 13 to about 17 wt.%, about 13 to about 15 wt.%; from about 15 to about 35 wt.%, about 15 to about 35 wt.%, about 15 to about 31 wt.%, about 15 to about 27 wt.%, about 15 to about 23 wt.%, about 15 to about 19 wt.%; from about 17 to about 35 wt.%, about 17 to about 35 wt.%, about 17 to about 31 wt.%, about 17 to about 27 wt.%, about 17 to about 23 wt.%; from about 19 to about 35 wt.%, about 19 to about 35 wt.%, about 19 to about 31 wt.%, about 19 to about 27 wt.%, about 19 to about 23 wt.%, or any range or subrange thereof, based on the total weight of the oral care composition.

[0084] The oral care compositions may include an abrasive system comprising two or more abrasives. For example, an abrasive system comprise 2 to 7, 2 to 6, 2 to 5, 2 to 5, or 2 to 4; 3 to 7, 3 to 6, 2 to 5, or 3 to 5 abrasives. The abrasives may comprise one or more cleaning abrasive and/or one or more polishing abrasives. As appreciated by one of skill in the art, a single abrasive species typically performs at least some cleaning and polishing simultaneously. However, particles are generally categorized in the art by the predominant effect they have on a target oral surface. Typically, “polishing abrasives” are considered to be relatively small particles having high hardness, where abrasives with relatively large particle sizes and low hardness are considered to be “cleaning abrasives.” In certain embodiments, the oral care composition comprises two or more abrasives comprising silica. In some embodiments, the first abrasive is selected to be a harder and smaller abrasive, e.g., a higher cleaning and/or polishing abrasive, and the second abrasive is a typical cleaning abrasive. In some embodiments, the oral care composition includes at least one polishing abrasive and/or at least one cleaning abrasive. Further examples of abrasives are disclosed in U.S. Patent Publication No. 2007/140986, which is incorporated herein in its entirety by reference for all purposes.

[0085] The abrasive(s) may have at least one of the following properties: N2BET surface area of less than 50 m²/g, an Einlehner hardness of from 4 to 11, an oil absorption of from 80 cc/100 g to 100 cc/100 g, or a combination of two or more thereof. The abrasive may have a N2BET surface area of from 1 m²/g to 50 m²/g, e.g., from 1 m²/g to 45, from 1 m²/g to 40 m²/g, from 1 m²/g to 35 m²/g, or from 1 m²/g to 30 m²/g. The abrasive may have an oil absorption of from 60 cc/100 g to 120 cc/100 g, from 70 cc/100 g to 110 cc/100 g, or from 80 cc/100 g to 100 cc/100 g, e.g., linseed oil absorption. Oil absorption may be determined by various means known by those of skill in the art. For example, oil absorption may be determined by absorption of linseed oil or dibutyl phthalate (DBP) per 100 grams or abrasive. Oil absorption values can be measured using the ASTM Rub- Out Method D281. In at least one embodiment, the one or more abrasive(s) comprises an abrasive (e g. a silica abrasive) having have N2 BET surface area of less than 50 m²/g and an Einlehner hardness of from 4 to 11, and an oil absorption of from 80 cc/100 g to 100 cc/100 g.

[0086] Additional examples of abrasives, which may be incorporated into or in some embodiments excluded from the oral care composition, include silica abrasive, silicate, silicon, alumina (including calcined aluminum oxide), aluminosilicates, bentonite, zeolite, kaolin, mica, siliceous or diatomaceous earth, pumice, calcium compounds, calcium carbonate, cuttlebone, composite resins (such as melamine resin, phenolic resin, and urea-formaldehyde resin), polycarbonate, silicon carbide, boron carbide, microcrystalline wax, microcrystalline cellulose (e.g., combinations of colloidal microcrystalline cellulose and carboxymethylcellulose) dicalcium phosphate, calcium pyrophosphate, dicalcium orthophosphate dihydrate, tricalcium phosphate, calcium polymetaphosphate, calcium carbonate, calcium bicarbonate, and a combination of two or more thereof. For example, the oral care composition may include one or more of abrasives chosen from dicalcium phosphate, calcium pyrophosphate, dicalcium orthophosphate dihydrate, tricalcium phosphate, calcium polymetaphosphate, calcium carbonate, calcium bicarbonate, or a combination of two or more thereof. In further embodiments, the oral care composition comprises an abrasive selected from calcium carbonate, dicalcium orthophosphate dihydrate, calcium pyrophosphate, tricalcium phosphate, calcium polymetaphosphate, insoluble sodium polymetaphosphate, hydrated alumina, resinous abrasive materials such as particulate condensation products of urea and formaldehyde, and combinations thereof.

[0087] As used herein, “mica” refers to any of a group of hydrous aluminum silicate minerals with plate morphology and/or perfect basal (micaceous) cleavage. Mica can be, for example, sheet mica, scrap mica or flake mica, as exemplified by muscovite, biotite or phlogopite type micas. Synthetic silicas include both silica gels and precipitated silicas that are prepared by the neutralization of aqueous silicate solutions with a strong mineral acid. Abrasives comprising silica may be useful in certain embodiments of the oral care composition.

[0088] The abrasive may comprise a silica abrasive, an insoluble phosphate, or a combination thereof. The abrasive(s) based on insoluble phosphate salts may be chosen from calcium pyrophosphate, dicalcium orthophosphate dihydrate, tricalcium phosphate, and calcium polymetaphosphate, and a combination of two or more thereof. The total amount of abrasives is preferably comprised primarily of calcium pyrophosphate and, in at least one embodiment, calcium pyrophosphate is the sole abrasive in the oral care composition. For example, the calcium pyrophosphate may comprise about 50 wt.% or more, about 60 wt.% or more, about 70 wt.% or more, about 80 wt.% or more, about 95 wt.% or more, about 98 wt.% or more, or about 99 wt.% or more of the total amount of the abrasive(s) in the oral care composition.

[0089] The oral care compositions preferably comprise water. The water may be present in an amount of about 10 wt.% or more, based on the total weight of the oral care composition. For instance, the oral care composition may include water in an amount from 10 to about 55 wt.%, about 10 to about 50 wt.%, about 10 to about 45 wt.%, about 10 to about 40 wt.%, about 10 to about 37 wt.%, about 10 to about 34 wt.%, about 10 to about 31 wt.%, about 10 to about 28 wt.%, about 10 to about 25 wt.%; from about 15 to about 55 wt.%, about 15 to about 50 wt.%, about 15 to about 45 wt.%, about 15 to about 40 wt.%, about 15 to about 37 wt.%, about 15 to about 34 wt.%, about 15 to about 31 wt.%, about 15 to about 28 wt.%, about 15 to about 25 wt.%; from about 20 to about 55 wt.%, about 20 to about 50 wt.%, about 20 to about 45 wt.%, about 20 to about 40 wt.%, about 20 to about 37 wt.%, about 20 to about 34 wt.%, about 20 to about 31 wt.%, about 20 to about 28 wt.%; from about 25 to about 55 wt.%, about 25 to about 50 wt.%, about 25 to about 45 wt.%, about 25 to about 40 wt.%, about 25 to about 37 wt.%, about 25 to about 34 wt.%, about 25 to about 31 wt.%; from about 28 to about 55 wt.%, about 28 to about 50 wt.%, about 28 to about 45 wt.%, about 28 to about 40 wt.%, about 28 to about 37 wt.%, about 28 to about 34 wt.%, about 28 to about 31 wt.%; from about 30 to about 55 wt.%, about 30 to about 50 wt.%, about 30 to about 45 wt.%, about 30 to about 40 wt.%, about 30 to about 37 wt.%, about 30 to about 34 wt.%; from about 33 to about 55 wt.%, about 33 to about 50 wt.%, about 33 to about 45 wt.%, about 33 to about 40 wt.%, about 33 to about 37 wt.%; from about 36 to about 55 wt.%, about 36 to about 50 wt.%, about 36 to about 45 wt.%, from about 39 to about 55 wt.%, about 39 to about 50 wt.%, about 39 to about 45 wt.%; from about 42 to about 55 wt.%, about 42 to about 50 wt.%, about 42 to about 48 wt.%; from about 45 to about 55 wt.%, about 45 to about 50 wt.%; from about 49 to about 55 wt.%; from about 53 to about 63 wt.%, about 53 to about 59 wt.%, or any range or subrange thereof, based on the total weight of the oral care composition. In some embodiments, the oral care composition comprises from about 30 wt.% to about 55 wt.% of water, based on the total weight of the oral care composition.

[0090] In some embodiments, however, the oral care compositions have water in an amount from up to about 7 wt.%, based on the total weight of the oral care compositions. For example, in certain embodiments, such as those containing whitening agents, the oral care composition comprises a total amount of water of up to about 5 wt.%, up to about 3 wt.%, up to about 2 wt.%, up to about

1 wt.%; from about 0.5 to about 5 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%, about 0.5 to about 1 wt.%; from about 1 to about 5 wt.%, about 1 to about 3 wt.%, about 1 to about

2 wt.%;from about 2 to about 5 wt.%, about 2 to about 3 wt.%, or any range or subrange thereof, based on the total weight of the oral care composition.

[0091] The oral care compositions may include one or more polyol(s). The one or more polyol(s) may be present in the oral care composition in an amount from about 5 to about 78 wt.%, based on the total weight of the oral care composition. For example, the oral care composition may include polyol(s) in an amount from about 5 to about 63 wt.%, about 5 to about 59 wt.%, about 5 to about 55 wt.%, about 5 to about 50 wt.%, about 5 to about 45 wt.%, about 5 to about 40 wt.%, about 5 to about 34 wt.%, about 5 to about 31 wt.%, about 5 to about 28 wt.%, about 5 to about 25 wt.%, about 5 to about 20 wt.%, about 5 to about 15 wt.%; from about 10 to about 78 wt.%, about 10 to about 63 wt.%, about 10 to about 59 wt.%, about 10 to about 55 wt.%, about 10 to about 50 wt.%, about 10 to about 45 wt.%, about 10 to about 40 wt.%, about 10 to about 37 wt.%, about 10 to about 34 wt.%, about 10 to about 31 wt.%, about 10 to about 28 wt.%, about 10 to about 25 wt.%; from about 15 to about 63 wt.%, about 15 to about 59 wt.%, about 15 to about 55 wt.%, about 15 to about 50 wt.%, about 15 to about 45 wt.%, about 15 to about 40 wt.%, about 15 to about 37 wt.%, about 15 to about 34 wt.%, about 15 to about 31 wt.%, about 15 to about 28 wt.%, about 15 to about 25 wt.%; from about 20 to about 78 wt.%, about 20 to about 63 wt.%, about 20 to about 59 wt.%, about 20 to about 55 wt.%, about 20 to about 50 wt.%, about 20 to about 45 wt.%, about 20 to about 40 wt.%, about 20 to about 37 wt.%, about 20 to about 34 wt.%, about 20 to about 31 wt.%, about 20 to about 28 wt.%; from about 25 to about 63 wt.%, about 25 to about 59 wt.%, about 25 to about 55 wt.%, about 25 to about 50 wt.%, about 25 to about 45 wt.%, about 25 to about 40 wt.%, about 25 to about 37 wt.%, about 25 to about 34 wt.%, about 25 to about 31 wt.%; from about 28 to about 63 wt.%, about 28 to about 59 wt.%, about 28 to about 37 wt.%, about 28 to about 34 wt.%, about 28 to about 31 wt.%; from about 31 to about 78 wt.%, about 31 to about 63 wt.%, about 31 to about 59 wt.%, about 31 to about 55 wt.%, about 31 to about 50 wt.%, about 31 to about 45 wt.%, about 31 to about 40 wt.%, about 31 to about 37 wt.%; from about 37 to about 78 wt.%, about 37 to about 63 wt.%, about 37 to about 59 wt.%, about 37 to about 55 wt.%, about 37 to about 50 wt.%, about 37 to about 45 wt.%; from about 43 to about 78 wt.%, about 43 to about 63 wt.%, about 43 to about 59 wt.%, about 43 to about 55 wt.%, about 43 to about 50 wt.%; from about 49 to about 78 wt.%, about 49 to about 63 wt.%, about 49 to about 59 wt.%, about 49 to about 55 wt.%; from about 53 to about 78 wt.%, about 53 to about 63 wt.%, about 53 to about 59 wt.%, about 62 to about 78 wt.%, or any range or subrange thereof, based on the total weight of the oral care composition.

[0092] The polyol(s) may be chosen from glycols or compounds with numerous hydroxyl groups. The one or more polyols may be liquid at ambient temperature (25°C). The polyol may be a humectant chosen from glycol, sorbitol, glycerin, inositol, maltitol, mannitol, xylitol, propylene glycol, polypropylene glycol (PPG), polyethylene glycol (PEG), a saccharide, poly oxypropylenepolyoxy ethylene block copolymer and a combination of two or more thereof.

[0093] The polyol(s) may be selected from glycerin, glycol, inositol, maltitol, mannitol, sorbitol, xylitol, propylene glycol, polypropylene glycol (PPG), polyethylene glycol (PEG), a block copolymer of PPG and PEG, a saccharide (e.g., fructose, glucose, sucrose and mixtures of saccharides, such as honey), or a combination of two or more thereof. For instance, the oral care composition may comprise maltitol, mannitol, sorbitol, xylitol, a polypropylene glycol (PPG), a polyethylene glycol (PEG), a block copolymer of PPG and PEG, or a combination or two or more thereof. [0094] In some cases, the oral care composition includes one or more polyol selected from the group consisting of C2-C32 polyols. The one or more polyols may have from 2 to 32 carbon atoms, from 3 to 16 carbon atoms, or from 3 to 12 carbon atoms. For example, the oral care composition may comprise ethylene glycol, propylene glycol, butylene glycol, hexylene glycol, glycerin, diglycerin, diethylene glycol, and dipropylene glycol, or a combination of two or more thereof. Additional, non-limiting examples of polyols that may, optionally, be incorporated in the oral care composition include alkanediols, such as glycerin, 1,2,6-hexanetriol, trimethylolpropane, ethylene glycol, propylene glycol, butylene glycol, pentylene glycol, hexylene glycol, diethylene glycol, triethylene glycol, tetraethylene glycol, pentaethylene glycol, dipropylene glycol, 2 -butene- 1,4- diol, 2-ethyl-l,3-hexanediol, 2-methyl-2,4-pentanediol, caprylyl glycol, 1,2-hexanediol, 1,2- pentanediol, and 4-methyl-l,2-pentanediol; glycol ethers, such as ethylene glycol monomethyl ether, ethylene glycol monoethyl ether, ethylene glycol monobutyl ether, ethylene glycol monomethyl ether acetate, diethylene glycol monomethyl ether, diethylene glycol monoethyl ether, diethylene glycol mono-n-propyl ether, ethylene glycol mono-iso-propyl ether, diethylene glycol mono-iso-propyl ether, ethylene glycol mono-n-butyl ether, ethylene glycol mono-t-butyl ether, diethylene glycol mono-t-butyl ether, 1 -methyl- 1 -methoxybutanol, propylene glycol monomethyl ether, propylene glycol monoethyl ether, propylene glycol mono-t-butyl ether, propylene glycol mono-n-propyl ether, propylene glycol mono-iso-propyl ether, dipropylene glycol monomethyl ether, dipropylene glycol monoethyl ether, dipropylene glycol mono-n-propyl ether, dipropylene glycol mono-iso-propyl ether, sorbitol, sorbitan, triacetin, and a mixture thereof. [0095] Additionally or alternatively, the oral care composition may include polyol(s) having a molecular weight of from about 100 to 5000 g/mol. For instance, the polyol may comprise a polyethylene glycol, a polypropylene glycol, a block polymer of polyethylene glycol and polypropylene glycol, or a combination of two or more thereof. In some embodiments, the polyol comprises a polypropylene glycol, a polypropylene glycol, and/or a block polymer of polyethylene glycol and polypropylene glycol having a molecular weight of about 100 to about 900, about 200 to about 800, about 400, about 1500 to about 2500, about 2000 to about 4500 or any range or subrange thereof. In some embodiments, the polyol is a polyethylene glycol, such as polyethylene glycol 600 (CAS-25322-68-3). In some embodiments, the oral care compositions comprise one or more polyethylene glycols, e.g., polyethylene glycols in a molecular weight range from 200 to 800. For example, the oral care composition may comprise polyethylene glycol 200, polyethylene glycol 300, polyethylene glycol 400, polyethylene glycol 600, polyethylene glycol 800, or a combination of two or more thereof.

[0096] The oral care compositions may include one or more surfactant(s) in various amounts. The oral care composition may comprise one or more anionic surfactant, one or more cationic surfactant, one or more nonionic surfactant, or a combination of two or more thereof. For example, the oral care composition may include one or more anionic surfactant(s) in an amount of about 0.5 to about 10 wt.%, based on the total weight of the oral care composition. In some instances, the anionic surfactant(s) is present in the oral care composition in an amount from about 0.5 to about 10 wt.%, about 0.5 to about 8 wt.%, about 0.5 to about 6 wt.%, about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%; from about 1 to about 10 wt.%, about 1 to about 8 wt.%, about 1 to about 6 wt.%, about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; from about 2 to about 10 wt.%, about 2 to about 8 wt.%, about 2 to about 6 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%; from about 3 to about 10 wt.%, about 3 to about 8 wt.%, about 3 to about 6 wt.%, about 3 to about 5 wt.%, about 3 to about 4 wt.%; from about 5 to about 10 wt.%, about 5 to about 8 wt.%, about 5 to about 6 wt.%; from about 7 to about 10 wt.%, about 7 to about 8 wt.%, about 8 to about 10 wt.%, or any range or subrange thereof, based on the total weight of the oral care composition.

[0097] The anionic surfactant(s) may be selected from sulfate based anionic surfactants and nonsulfate based anionic surfactants. For example, the oral care composition may include an anionic surfactant chosen from ammonium lauryl sulfate, ammonium lauryl ether sulfate, sodium dodecyl sulfate, sodium coco-sulfate, ammonium coco-sulfate, sodium lauryl sulfate, sodium lauryl ether sulfate, and a combination of two or more thereof. In some preferred embodiments, the oral care composition comprises sodium lauryl sulfate, sodium lauryl ether sulfate, or a combination thereof. In further embodiments, one or more anionic surfactant is selected from sodium lauryl sulfate, sodium lauryl ether sulfate, sodium lauryl sarcosinate, sodium cocoyl methyl taurate, sodium monoglyceride sulfate, sodium cetaryl sulfate, potassium cocoyl glycinate, sodium lauryl phosphate, sodium lauryl lactylate, sodium lauryl sulfoacetate, sodium lauryl glutamate, sodium lauryl isethionate, sodium laureth carboxylate, sodium dodecyl benzenesulfonate, and a combination of two or more thereof. [0098] The one or more anionic surfactant(s) may be selected from non-sulfate based anionic surfactants, such as sulfonated monoglycerides of fatty acids, acyl isethionates, acyl sarcosinates, acyl taurate, and a combination of two or more thereof. Non-limiting examples of acyl isethionates include sodium isethionate, sodium cocoyl isethionate, sodium lauroyl methyl isethionate, and sodium cocoyl methyl isethionate. Sulfonated monoglycerides of fatty acids include sodium coconut monoglyceride sulfonates and the like. Examples of acyl sarcosinates include potassium lauroyl sarcosinate, potassium cocoyl sarcosinate, sodium cocoyl sarcosinate, sodium lauroyl sarcosinate, sodium myristoyl sarcosinate, sodium oleoyl sarcosinate, sodium palmitoyl sarcosinate, ammonium lauroyl sarcosinate, and combinations of two or more thereof. Examples of acyl taurate surfactants include sodium cocoyl taurate, potassium cocoyl taurate, potassium methyl cocoyl taurate, sodium caproyl methyl taurate, sodium cocoyl taurate, sodium lauroyl taurate, sodium methyl cocoyl taurate (SMCT), sodium methyl lauroyl taurate, sodium methyl myristoyl taurate, sodium methyl oleoyl taurate, sodium methyl palmitoyl taurate, sodium methyl stearoyl taurate, and combinations of two or more thereof. In some embodiments, the oral care composition comprises sodium lauroyl methyl taurate (or sodium methyl lauroyl taurate), sodium methyl cocoyl taurate (SMCT), or a combination thereof.

[0099] The anionic surfactant(s) may have at least one acyl group, preferably, comprising a carbon chain of 8 to 21 carbons. In some instance, the alkyl group(s) of the anionic surfactant(s) comprise a carbon chain of 8 to 19 carbons, 8 to 17 carbons, 8 to 15 carbons, 8 to 13 carbons, 8 to 11 carbons; 9 to 21 carbons, 9 to 19 carbons, 9 to 17 carbons, 9 to 15 carbons, 9 to 13 carbons, 9 to 11 carbons; 11 to 21 carbons, 11 to 19 carbons, 11 to 17 carbons, 11 to 15 carbons, 11 to 13 carbons; 13 to 21 carbons, 13 to 19 carbons, 13 to 17 carbons, or any range or subrange thereof. The anionic surfactants disclosed herein may be incorporated in a salt form. The salt form of the anionic surfactants may have an alkali metal (e.g., sodium or potassium) and/or ammonium group.

[0100] Additionally or alternatively, the oral care composition may comprise one or more nonionic surfactant(s). The oral care composition may include nonionic surfactant(s) in an amount of about 0.5 to about 10 wt.%, based on the total weight of the oral care composition. In some instances, the nonionic surfactant(s) is present in the oral care composition in an amount from about 0.5 to about 10 wt.%, about 0.5 to about 8 wt.%, about 0.5 to about 6 wt.%, about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%; from about 1 to about 10 wt.%, about 1 to about 8 wt.%, about 1 to about 6 wt.%, about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; from about 2 to about 10 wt.%, about 2 to about 8 wt.%, about 2 to about 6 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%; from about 3 to about 10 wt.%, about 3 to about 8 wt.%, about 3 to about 6 wt.%, about 3 to about 5 wt.%, about 3 to about 4 wt.%; from about 5 to about 10 wt.%, about 5 to about 8 wt.%, about 5 to about 6 wt.%; from about 7 to about 10 wt.%, about 7 to about 8 wt.%, about 8 to about 10 wt.%, or any range or subrange thereof, based on the total weight of the oral care composition.

[0101] The one or more nonionic surfactant(s) may be selected from glucosides, compounds produced by the condensation of alkylene oxide groups (hydrophilic in nature) with an organic hydrophobic compound, which may be aliphatic or alkylaromatic in nature. Examples of glucoside surfactants include decyl glucoside, stearyl glucoside, lauryl glucoside, coco-glucoside, cetearyl glucoside, decyl lauryl glucoside, lauroyl ethyl glucoside, myristoyl ethyl glucoside, oleoyl ethyl glucoside, or a combination of two or more thereof. In some embodiments, the surfactant system includes one or more nonionic surfactant(s) chosen from lauryl glucoside, lauroyl ethyl glucoside, myristoyl ethyl glucoside, oleoyl ethyl glucoside, and a combination of two or more thereof. Additionally or alternatively, the glucoside surfactant may be chosen from polyglucosides, such as alkylpolyglucosides.

[0102] Further examples of nonionic surfactants include poloxamers, polyethylene oxide condensates of alkyl phenols, products derived from the condensation of ethylene oxide with the reaction product of propylene oxide and ethylene diamine, ethylene oxide condensates of aliphatic alcohols, acids, and esters, long chain tertiary amine oxides, long chain tertiary phosphine oxides, long chain dialkyl sulfoxides and mixtures of such materials. Additional examples of nonionic surfactants include polyoxyethylene, polyoxyethylene sorbitan esters, polyoxyl n4o-6o hydrogenated castor oil, fatty alcohol ethoxylates, polyethylene oxide condensates of alkyl phenols, products derived from the condensation of ethylene oxide with the reaction product of propylene oxide and ethylene diamine, ethylene oxide condensates of aliphatic alcohols, long chain tertiary amine oxides, long chain tertiary phosphine oxides, long chain dialkyl sulfoxides, or a combination of two or more thereof. In some instances, the nonionic surfactant comprises amine oxides, fatty acid amides, ethoxylated fatty alcohols, block copolymers of polyethylene glycol and polypropylene glycol, glycerol alkyl esters, polyoxyethytene glycol octylphenol ethers, sorbitan alkyl esters, polyoxyethylene glycol sorbitan alkyl esters, or a combination of two or more thereof. [0103] In some embodiments, the oral care composition may comprise one or more cationic surfactant(s). The oral care composition may include cationic surfactant(s) in an amount of about 0.5 to about 10 wt.%, based on the total weight of the oral care composition. In some instances, the cationic surfactant(s) is present in the oral care composition in an amount from about 0.5 to about 10 wt.%, about 0.5 to about 8 wt.%, about 0.5 to about 6 wt.%, about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%; from about 1 to about 10 wt.%, about 1 to about 8 wt.%, about 1 to about 6 wt.%, about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; from about 2 to about 10 wt.%, about 2 to about 8 wt.%, about 2 to about 6 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%; from about 3 to about 10 wt.%, about 3 to about 8 wt.%, about 3 to about 6 wt.%, about 3 to about 5 wt.%, about 3 to about 4 wt.%; from about 5 to about 10 wt.%, about 5 to about 8 wt.%, about 5 to about 6 wt.%; from about 7 to about 10 wt.%, about 7 to about 8 wt.%, about 8 to about 10 wt.%, or any range or subrange thereof, based on the total weight of the oral care composition.

[0104] Examples of cationic surfactants that may be present in the oral care composition include cetyl pyridinium chloride, coamidopropyl PG dimonium chloride phosphate (Phospholipid CDM), myristylamidopropyl PG dimonium chloride phosphate (Phospholipid PTM), stearamidopropyl PG dimonium chloride phosphate (Phospholipid SV), steapyrium chloride (Catemol WPC), and other suitable cationic materials. The cationic surfactants may be present in the form of a salt.

[0105] The oral care compositions may include an anti -cal cuius agent. The amount of anti -cal cuius agent(s) present in the oral are composition may be from about 0.5 to about 10 wt.%, based on the total weight of the oral care composition. In some instances, the anti-calculus agent(s) is present in the oral care composition in an amount from about 0.5 to about 10 wt.%, about 0.5 to about 8 wt.%, about 0.5 to about 6 wt.%, about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%; from about 1 to about 10 wt.%, about 1 to about 8 wt.%, about 1 to about 6 wt.%, about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; from about 2 to about 10 wt.%, about 2 to about 8 wt.%, about 2 to about 6 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%; from about 3 to about 10 wt.%, about 3 to about 8 wt.%, about 3 to about 6 wt.%, about 3 to about 5 wt.%, about 3 to about 4 wt.%; from about 5 to about 10 wt.%, about 5 to about 8 wt.%, about 5 to about 6 wt.%; from about 7 to about 10 wt.%, about 7 to about 8 wt.%, about 8 to about 10 wt.%, or any range or subrange thereof, based on the total weight of the oral care composition.

[0106] The oral care compositions may include anti-calculus agents chosen from phosphates and polyphosphates (e.g., pyrophosphates), polyaminopropanesulfonic acid (AMPS), hexametaphosphate salts, zinc citrate trihydrate, polypeptides, polyolefin sulfonates, polyolefin phosphates, diphosphonates, and combinations of two or more thereof. Examples of additional anti-calculus agents include tetrasodium pyrophosphate, ammonium tripolyphosphate, hexametaphosphate salt, polycarboxylate polymers, polyvinyl methyl ether/maleic anhydride (PVME/MA) copolymers, or combinations of two or more thereof. In some embodiments, the oral care composition includes one or more alkali metal polyphosphate, such as tetrasodium pyrophosphate.

[0107] The oral care compositions may include a fluoride ion source. The fluoride ion source may be present in an effective amount. In some cases, the fluoride ion source is present in the oral care composition in an amount of about 0. 1 to about 7 wt.%, based on the total weight of the oral care composition. For example, the fluoride ion source may be present in an amount of about 0.1 to about 7 wt.%, about 0.1 to about 5 wt.%, about 0.1 to about 3 wt.%, about 0.1 to about 2 wt.%, about 0.1 to about 1 wt.%; from about 0.4 to about 7 wt.%, about 0.4 to about 5 wt.%, about 0.4 to about 3 wt.%, about 0.4 to about 2 wt.%, about 0.4 to about 1 wt.%; from about 0.8 to about 7 wt.%, about 0.8 to about 5 wt.%, about 0.8 to about 3 wt.%, about 0.8 to about 2 wt.%, about 0.8 to about 1.5 wt.%; from about 1 .4 to about 7 wt.%, about 1 .4 to about 5 wt.%, about 1 .4 to about 3 wt.%; from about 2 to about 7 wt.%, about 2 to about 5 wt.%, about 2 to about 3 wt.%; from about 3 to about 7 wt.%, about 3 to about 5 wt.%, about 3 to about 4 wt.%; from about 4 to about 7 wt.%, about 4 to about 6 wt.%, about 4 to about 5 wt.%; from about 5 to about 7 wt.%, about 5 to about 6 wt.%, or any range or subrange thereof, based on the total weight of the oral care composition.

[0108] The fluoride ion source may be selected from soluble fluoride ion salts. For example, the fluoride ion source may comprise sodium fluoride, potassium fluoride, calcium fluoride, zinc fluoride, zinc ammonium fluoride, lithium fluoride, ammonium fluoride, stannous fluoride, stannous fluor ozirconate, sodium monofluorophosphate, potassium monofluorophosphate, laurylamine hydrofluoride, diethylaminoethyloctoylamide hydrofluoride, didecyldimethylammonium fluoride, cetylpyridinium fluoride, dilaurylmorpholinium fluoride, sarcosine stannous fluoride, glycine potassium fluoride, glycine hydrofluoride, amine fluorides or a combination of two or more thereof. In some embodiments, the fluoride ion source comprises sodium fluoride, sodium monofluorophosphate, or a combination thereof. Additional examples of fluoride ion sources are disclosed in U.S. Patent No. 3,535,421, U.S. Patent No. 4,885,155, and U.S. Patent No. 3,678,154, the disclosures of which are hereby incorporated by reference in their entirety for all purposes.

[0109] The oral care compositions may, optionally, include one or more whitening agent. The amount of whitening agent(s), if present, in the oral care composition may be from about 1 to about 30 wt.%, based on the total weight of the oral care composition. For example, the whitening agent(s) may be present in the oral care composition in an amount from about 1 to about 30 wt.%, about 1 to about 26 wt.%, about 1 to about 22 wt.%, about 1 to about 19 wt.%, about 1 to about 16 wt.%, about 1 to about 13 wt.%, about 1 to about 10 wt.%, about 1 to about 8 wt.%, about 1 to about 6 wt.%, about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; from about 2 to about 30 wt.%, about 2 to about 26 wt.%, about 2 to about 22 wt.%, about 2 to about 19 wt.%, about 2 to about 16 wt.%, about 2 to about 13 wt.%, about 2 to about 10 wt.%, about 2 to about 8 wt.%, about 2 to about 6 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%; from about 3 to about 30 wt.%, about 3 to about 26 wt.%, about 3 to about 22 wt.%, about 3 to about 19 wt.%, about 3 to about 16 wt.%, about 3 to about 13 wt.%, about 3 to about 10 wt.%, about 3 to about 8 wt.%, about 3 to about 6 wt.%; from about 5 to about 30 wt.%, about 5 to about 26 wt.%, about 5 to about 22 wt.%, about 5 to about 19 wt.%, about 5 to about 16 wt.%, about 5 to about 13 wt.%, about 5 to about 10 wt.%, about 5 to about 8 wt.%; from about 8 to about 30 wt.%, about 8 to about 26 wt.%, about 8 to about 22 wt.%, about 8 to about 19 wt.%, about 8 to about 16 wt.%, about 8 to about 13 wt.%; from about 11 to about 30 wt.%, about 11 to about 26 wt.%, about 11 to about 22 wt.%, about 11 to about 19 wt.%, about 11 to about 16 wt.%; from about 14 to about 30 wt.%, about 14 to about 26 wt.%, about 14 to about 22 wt.%, about 14 to about 19 wt.%; from about 18 to about 30 wt.%, about 18 to about 26 wt.%, about 18 to about 22 wt.%, or any range or subrange thereof, based on the total weight of the oral are composition. [0110] The whitening agent(s) typically comprise a peroxide, such as hydrogen peroxide, peroxides of alkali and alkaline earth metals, organic peroxy compounds, peroxy acids, salts thereof, or combinations of two or more thereof. Peroxides of alkali and alkaline earth metals include lithium peroxide, potassium peroxide, sodium peroxide, magnesium peroxide, calcium peroxide, barium peroxide, and a combination of two or more thereof Examples of organic peroxy compounds include carbamide peroxide (also known as urea hydrogen peroxide), glyceryl hydrogen peroxide, alkyl hydrogen peroxides, dialkyl peroxides, alkyl peroxy acids, peroxy esters, diacyl peroxides, benzoyl peroxide, monoperoxyphthalate, or a combination of two or more thereof. Peroxy acids and their salts include organic peroxy acids, such as alkyl peroxy acids, monoperoxyphthalate, and a combination thereof as well as inorganic peroxy acid salts, such as persulfate, dipersulfate, percarbonate, perphosphate, perborate and persilicate salts of alkali and/or alkaline earth metals, such as lithium, potassium, sodium, magnesium, calcium and barium, and mixtures thereof. In various embodiments, the peroxide compound comprises hydrogen peroxide, urea peroxide, sodium percarbonate, or a combination of two or more thereof.

[0U1] The one or more peroxide(s) may be a non-complexed peroxide. The non-complexed peroxide may be chosen from one or more of the peroxides described above. In some preferred embodiments, the non-complexed peroxide comprises hydrogen peroxide.

[0112] The total amount of whitening agent may comprise from about 0.01 to about 10 wt.% of a non-complexed peroxide source, based on the total weight of the oral care composition. For example, the whitening agent may comprise a non-complexed peroxide source in an amount from about 0.01 to about 10 wt.%, about 0.01 to about 8 wt.%, about 0.01 to about 6 wt.%, about 0.01 to about 4 wt.%, about 0.01 to about 3 wt.%, about 0.01 to about 2 wt.%, about 0.01 to about 1 wt.%; from about 0.1 to about 10 wt.%, about 0.1 to about 8 wt.%, about 0.1 to about 6 wt.%, about 0.1 to about 4 wt.%, about 0.1 to about 3 wt.%, about 0.1 to about 2 wt.%, about 0.1 to about 1 wt.%; from about 0.5 to about 10 wt.%, about 0.5 to about 8 wt.%, about 0.5 to about 6 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%, about 0.5 to about 1 wt.%; from about 1 to about 10 wt.%, about 1 to about 8 wt.%, about 1 to about 6 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; from about 2 to about 10 wt.%, about 2 to about 8 wt.%, about 2 to about 6 wt.%, about 2 to about 4 wt.%; from about 3 to about 10 wt.%, about 3 to about 8 wt.%, about 3 to about 6 wt.%, about 3 to about 4 wt.%; from about 4 to about 10 wt.%, about 4 to about 8 wt.%, about 4 to about 6 wt.%, or any range or subrange thereof, based on the total weight of the oral care composition.

[0113] In some embodiments, however, the whitening agent may comprise a peroxide complex. The peroxide complex may comprise a peroxide component and a porous cross-linked polymer. As referred to herein, a “peroxide component” is any oxidizing compound comprising a bivalent oxygen-oxygen group. Peroxide components include peroxides and hydroperoxides disclosed above, such as hydrogen peroxide, peroxides of alkali and alkaline earth metals, organic peroxy compounds, peroxy acids, salts thereof, and mixtures thereof. In various embodiments, the peroxide component comprises hydrogen peroxide, urea peroxide, sodium percarbonate and mixtures thereof. In one embodiment, the peroxide component comprises hydrogen peroxide. In one embodiment, the peroxide component consists essentially of hydrogen peroxide.

[0114] The peroxide complex may also be selected from N-vinyl heterocyclic polymers. Preferably, the N-vinyl heterocyclic polymer is crosslinked and adsorbs, absorbs, complexes, or otherwise retains the peroxide component. The chemical and physical characteristics of the particulate hinder the release of the peroxide compound from the polymer particulates, and in some embodiments provides controlled release of the peroxide compound. The peroxide complex preferably comprises a peroxide component at a level of from about 0.1 to about 25 wt.%, from about 1 to about 25 wt.%, from about 5 to about 18 wt.%, based on the weight of the peroxide complex. In some preferred embodiments, the oral care composition comprises a complex of peroxide adsorbed to cross-linked polyvinylpyrrollidone.

[0115] In some embodiments, a non-peroxide whitening agent may be included in the oral care composition. Whitening agents among those useful herein include non-peroxy compounds, such as chlorine dioxide, chlorites and hypochlorites. Chlorites and hypochlorites include those of alkali and alkaline earth metals such as lithium, potassium, sodium, magnesium, calcium and barium. Non-peroxide whitening agents also include colorants, such as titanium dioxide and hydroxyapatite, pigments, or dyes.

[0116] The oral care compositions may include a desensitizing agent. The amount of desensitizing agent may be from about 0.5 to about 9 wt.%, based on the total weight of the oral care composition. For example, the amount of desensitizing agent present in the oral care composition may be from about 0.5 to about 8 wt.%, about 0.5 to about 6 wt.%, about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%; from about 1 to about 9 wt.%, about 1 to about 8 wt.%, about 1 to about 6 wt.%, about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; from about 2 to about 9 wt.%, about 2 to about 8 wt.%, about 2 to about 6 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%; from about 3 to about 9 wt.%, about 3 to about 8 wt.%, about 3 to about 6 wt.%, about 3 to about 5 wt.%, about 3 to about 4 wt.%; from about 4 to about 9 wt.%, about 4 to about 8 wt.%, about 4 to about 6 wt.%, about 4 to about 5 wt.%; from about 5 to about 9 wt.%, about 5 to about 8 wt.%, about 5 to about 6 wt.%; from about 6 to about 9 wt.%, about 6 to about 8 wt.%; from about 7 to about 9 wt.%, about 7 to about 8 wt.%, about 8 to about 10 wt.%, or any range or subrange therefrom, based on the total weight of the oral care composition.

[0117] The desensitizing agent(s) may comprise, e.g., benzocaine, potassium nitrate; potassium fluoride; strontium chloride; potassium chloride; potassium citrate; iron oxalate; sodium nitrate; lithium nitrate; magnesium nitrate; calcium nitrate; calcium hydroxide; dibasic calcium phosphate; strontium acetate; sodium monofluorophosphate; bisabolol; a local or systemic analgesic agent such as NSAIDS, aspirin, acetaminophen and/or codeine; or combinations of two or more thereof. For example, the desensitizing agent(s) may be chosen from potassium nitrate, potassium citrate, potassium chloride, potassium bicarbonate, potassium oxalate, and a combination of two or more thereof. In some embodiments, the desensitizing agent is potassium nitrate.

[0118] In some embodiments, the oral care compositions may include one or more sweeteners. The oral care composition may include caloric sweeteners and/or non-caloric sweeteners. Examples of non-caloric sweeteners include saccharin, e.g., sodium saccharin, acesulfame, neotame, cyclamate or sucralose; natural high-intensity sweeteners, such as thaumatin, stevioside or glycyrrhizin; or sugar alcohols, such as sorbitol, xylitol, maltitol and mannitol. Examples of caloric sweeteners include sugars, such as fructose, glucose, sucrose, and high fructose syrups. [0119] The one or more sweetener(s) may be present in the oral care composition in an amount from about 0.1 to about 7 wt.%, based on the total weight of the oral care composition. For example, the oral care composition may have a total amount of sweetener(s) from about 0.1 to about 5 wt.%, about 0.1 to about 4 wt.%, about 0.1 to about 3 wt.%, about 0.1 to about 2 wt.%, about 0.1 to about 1 wt.%; from about 0.5 to about 7 wt.%, about 0.5 to about 5 wt.%, about 0.5 to about 4 wt.%, about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%, about 0.5 to about 1 wt.%; from about 1 to about 7 wt.%, about 1 to about 5 wt.%, about 1 to about 4 wt.%, about 1 to about 3 wt.%, about 1 to about 2 wt.%; from about 2 to about 7 wt.%, about 2 to about 5 wt.%, about 2 to about 4 wt.%, about 2 to about 3 wt.%; from about 3 to about 7 wt.%, about 3 to about 5 wt.%, about 3 to about 4 wt.%; from about 4 to about 7 wt.%, about 4 to about 5 wt.%; from about 5 to about 7 wt.%, or any range or subrange thereof, based on the total weight of the oral care composition. [0120] In some embodiments, the oral care composition preferably is substantially free or free of caloric sweeteners. For example, the oral care compositions may have about 4 wt.% or less, about 3 wt.% or less, about 2 wt.% or less, about 1 wt.% or less, about 0.5 wt.% or less, or about 0.1 wt.% or less, based on the weight of the oral care composition. In at least one embodiment, the oral care composition contains about 0 wt.% or 0 wt.% of caloric sweeteners, based on the weight of the oral care composition.

[0121] The oral care compositions of the present disclosure may include a flavoring agent. The flavoring agent is typically incorporated in the oral care composition at a concentration of about 0.01 to about 3 wt.% by weight of the oral care composition. For example, the amount of flavoring agent(s) present in the oral care composition may be from about 0.01 to about 2 wt.%, about 0.01 to about 1 wt.%, about 0.01 to about 0.5 wt.%, about 0.01 to about 0.1 wt.%; from about 0.1 to about 3 wt.%, about 0.1 to about 2 wt.%, about 0.1 to about 1 wt.%, about 0.1 to about 0.5 wt.%; from about 0.5 to about 3 wt.%, about 0.5 to about 2 wt.%, about 0.5 to about 1 wt.%; from about 1 to about 3 wt.%, about 1 to about 2 wt.%; from about 2 to about 3 wt.%, including any range or subrange thereof, based on the total weight of the oral care composition.

[0122] Suitable flavoring agents include, but are not limited to, essential oils and various flavoring aldehydes, esters, alcohols, and similar materials. Examples of the essential oils include oils of spearmint, peppermint, wintergreen, sassafras, clove, sage, eucalyptus, maijoram, cinnamon, lemon, lime, grapefruit, and orange. Also useful are such chemicals as menthol, carvone, and anethole. Additional flavoring agents may include, but are not limited to menthol, artificial vanilla, cinnamon derivatives, various fruit flavors, spearmint oil, peppermint oil, cinnamon oil, oil of wintergreen (methylsalicylate), clove oil, bay oil, anise oil, eucalyptus oil, thyme oil, cedar leaf oil, oil of nutmeg, oil of sage, oil of bitter almonds, cassia oil, and a combination of two or more thereof.

[0123] The oral care compositions may include one or more colorants. Exemplary colorants can include natural or uncertified colors from natural sources or certified colors for the effect of color. In some embodiments, the colorant can include dyes, certified aluminum lakes or colors derived from a natural source. The colorant may be water-based, oil-based or dry. The colorants can be primary colors, blends of colors or discrete mixtures of colors, such as confetti. The concentrations of the colorant in the oral care composition may be from trace amount to about 0.6 wt.%, from about 0.1 to about 0.5 wt.%, about 0.2 to about 0.4 wt.%, or about 0.15 to about 0.35 wt.%, based on the total weight of the oral care composition.

[0124] The oral care composition may include one or more pH adjusters to increase or decrease the overall pH of the oral care composition. For example, one or more acids may be included to decrease the pH of the oral care composition. Examples of suitable acids for decreasing the pH of the oral care composition include, but are not limited to, citric acid, acetic acid, and the like. The oral care composition may include one or more bases, such as sodium hydroxide, potassium hydroxide and the like, to increase the pH of the oral care composition. Additional or alternative acids and bases that are suitable for adjusting the pH of the oral care composition are readily known to one of ordinary skill in the art.

[0125] The amount of the pH adjuster in the oral care composition may be based on the desired pH of the final oral care composition and/or product. For example, the total amount of the pH adjuster may range from about 0.05 to about 20 wt.%, based on the total weight of the oral care composition. In some instances, the total amount of pH adjuster is from about 0.05 to about 15 wt.%, about 0.1 to about 10 wt.%, or about 0.12 to about 5 wt.%, including ranges and sub-ranges thereof, based on the total weight of the oral care composition.

[0126] In accordance with further aspects of the invention, provided is a method for enhancing the shine of a tooth, the method comprising increasing the molar ratio of calcium to carbon on a surface of the tooth using an oral care composition comprising a polymer network formed of at least one of cross linked polyvinylpyrrolidone or ammonium acryloyl di methyltaurate/VP copolymer and insoluble phosphate contained in the polymer network. The methods typically comprise applying any of the oral compositions as described herein to the teeth, e.g., by brushing, rubbing, swishing when the oral care composition is in the form of a dentifrice, or otherwise administering the oral care compositions to the oral cavity of a subject. The oral care compositions can be administered regularly, such as, for example, one or more times per day.

[0127] The method may comprise using the dentifrice by applying the dentifrice to a tooth and brushing such tooth. One of ordinary skill in the art would recognize that the brushing of such tooth may be accomplished by applying the dentifrice to a toothbrush — such as the toothbrushes disclosed in U.S. Patent No. 10,595,628, which is incorporated herein in its entirety for all purposes — and brushing one or more teeth with the dentifrice and toothbrush. In some embodiments, the method includes brushing the one or more teeth for about 30 seconds to about 3 minutes, e.g., about 1 minute to about 3 minutes, about 1.5 minutes to about 3 minutes, about 2 minutes to about 3 minutes; from about 1 minute to about 2.5 minutes, about 1.5 minutes to about 2.5 minutes, about 2 minutes to about 2.5 minutes; about 1 minute to about 2 minutes, about 1.5 minutes to about 2 minutes, or any range or subrange thereof.

[0128] In yet further aspects of the invention, disclosed is a use of an oral care composition (e g. in the form of a dentifrice) for enhancing the shine of a tooth by increasing the molar ratio of calcium to carbon on a surface of the tooth, the oral care composition (e.g. in the form of a dentifrice) comprising a polymer network formed of at least one of cross linked polyvinylpyrrolidone or ammonium acryloyldimethyltaurate/VP copolymer and insoluble phosphate contained in the polymer network. The oral care compositions disclosed herein may be used for enhancing the shine and/or polish of a tooth.

EXAMPLES

Example 1

[0129] Four non-limiting, example oral care compositions (Example Compositions A-D and B) were prepared in accordance with aspects of the invention. Additionally, two comparative compositions (Comparative Compositions 1 and 2) were prepared. The formulations for Example Compositions A-D and Comparative Compositions 1 and 2 are shown in Table 1.

Table 1

Example 2

[0130] Sixteen oral care compositions (Compositions 3-18) were prepared to further evaluate the polymer networks formed in certain embodiments. The formulations for preparing Compositions 3-18 are provided in Table 2. It is worth noting that the amount of calcium pyrophosphate, propylene glycol, water, and sodium lauryl sulfate used to prepare Compositions 3-18 were the same.

Table 2

Table 2 (Continued)

Table 2 (Continued)

Example 3

[0131] Compositions 3-18 were mixed with water to form a slurry have a weight ratio of the respective composition to water of 1 : 1. The viscosity of the slurries formed from Compositions 3-19 were then evaluated at room temperature (e.g., 20 °C) using a Brookfield viscometer and a spindle number 74 at a spindle rotation of 1 rpm. The viscosity for Compositions 3-18 are shown in Table 3.

Table 3

[0132] It was determined that slurries having CMC, xanthan gum, or carrageenan, alone or in combination with the fumed silica, did not obtain a desirable polymer network as did slurries formed from oral care compositions in accordance with aspects of the disclosure.

Example 4

[0133] Two non-limiting, example oral care compositions (Example Compositions E and F) were prepared in the form a dentifrice in accordance with aspects of the invention. Additionally, a comparative composition (Comparative Composition 19) was prepared, which was also in the form of a dentifrice. The formulations for preparing Example Compositions E and F as well as Comparative Composition 19 are shown in Table 4. The amount of calcium pyrophosphate, sodium lauryl sulfate, PEG/PPG 116/66 copolymer, and sodium monofluorophosphate used to prepare Comparative Composition 19 and Example Compositions E and F were the same.

Table 4

[0134] Example Compositions E and F and Comparative Composition 19 were evaluated to determine the enamel polishing potential. Specifically, bovine teeth were utilized to evaluate the enamel polishing potential of the respective dentifrice compositions. An initial polish score for each of the bovine teeth was obtained using a Novo-Curve Glossmeter. The bovine teeth were scored by centering the enamel surface on the Glossmeter and marking each bovine tooth according to the lines 1, 2, 3, and 4 then rotating it 90° and scoring it again. The average of the two scores was used to calculate the Glossmeter data.

[0135] Following the baseline scoring, the bovine teeth were placed on a cross-brushing machine. The brush tension was adjusted to 150 grams and the specimens were brushed for 4,500 strokes with a slurry formed from 25 grams of the respective dentifrice and 40 grams of water using a toothbrush that is specified by ISO 11609. The bovine teeth were then rinsed and scored once again for polishing effects.

[0136] The difference between the initial polish score and the post-brushing polish score was calculated for each bovine tooth, with the difference in polishing score representing the enamel polishing potential. The mean, standard deviation, and standard error of the enamel polishing potential were calculated.

[0137] The enamel polishing potential for each of Example Compositions E and F and Comparative Composition 19 is shown in Table 4. Notably, Example Compositions E and F exhibited an enamel polishing potential that was about 30% greater than the enamel polishing potential of Comparative Composition 19.

Claims

CLAIMS What Is Claimed Is:

1. An oral care composition comprising: from about 0.1 to about 20 wt.% of one or more gelling agent comprising a cross linked polyvinylpyrrolidone, an ammonium acryloyldimethyltaurate/VP copolymer, or a combination of two or more thereof; and from about 1 to about 35 wt.% of one or more abrasive comprising an insoluble phosphate, wherein all weight percentages are based on the total weight of the oral care composition.

2. The oral care composition according to claim 1 comprising a polymer network formed from at least the one or more gelling agent.

3. The oral care composition according to claim 2, wherein the polymer network consists essentially of the one or more gelling agent.

4. The oral care composition according to claim 2 or claim 3, wherein polymer network contains the insoluble phosphate therein.

5. The oral care composition according to claim 4, wherein the polymer network is bonded to the insoluble phosphate therein.

6. The oral care composition according to any of claim 2 to claim 5, wherein the polymer network comprises a plurality of clusters formed of the insoluble phosphate.

7. The oral care composition according to any foregoing claim, wherein the insoluble phosphate is an insoluble phosphate salt selected from calcium pyrophosphate, dicalcium orthophosphate dihydrate, tricalcium phosphate, and calcium polymetaphosphate, and a combination of two or more thereof.

8. The oral care composition according to any foregoing claim, wherein the one or more abrasive comprises calcium pyrophosphate.

9. The oral care composition according to any foregoing claim, wherein the oral care composition comprises about 10 wt.% or more of water, optionally from about 30 wt.% to about 55 wt.% of water.

10. The oral care composition according to any foregoing claim, wherein the oral care composition has about 7 wt.% or less of natural polymers.

11. The oral care composition according to any foregoing claim, wherein the oral care composition has a total amount of all polymers of about 7 wt.% or less.

12. The oral care composition according to any foregoing claim further comprising: a polyol, optionally, in an amount from about 5 to about 63 wt.%.

13. The oral care composition according to claim 11, wherein the polyol is selected from ethylene glycol, propylene glycol, butylene glycol, hexylene glycol, glycerin, diglycerin, diethylene glycol, dipropylene glycol, triethylene glycol, tetraethylene glycol, pentaethylene glycol, dipropylene glycol, 2-butene-l,4-diol, 2-ethyl-l,3-hexanediol, 2-methyl-2,4-pentanediol, caprylyl glycol, 1,2-hexanediol, 1,2-pentanediol, and 4-methyl-l,2-pentanediol, and a combination of two or more thereof.

14. The oral care composition according to any foregoing claim, wherein the one or more gelling agent comprises from about 0.3 to about 5 wt.%, preferably about 0.3 to about 4 wt.%, about 0.3 to about 3 wt.%, or about 0.3 to about 2.5 wt.%, of acryloyldimethyltaurate/VP copolymer.

15. The oral care composition according to any foregoing claim, wherein the one or more gelling agent comprises from about 0.3 to about 6 wt.%, preferably about 0.3 to about 5 wt.%, about 0.3 to about 4 wt.%, or about 0.3 to about 3 wt.% of a sodium polyacryloyldimethyltaurate.

16. The oral care composition according to any foregoing claim further comprising: an anti -cal cuius agent, optionally, in an amount from about 0.5 to about 10 wt.%.

17. The oral care composition according to claim 16, wherein the anti-calculus agent is selected from tetrasodium pyrophosphate, ammonium tripolyphosphate, hexametaphosphate salt, polycarboxylate polymers, polyvinyl methyl ether/maleic anhydride (PVME/MA) copolymers, and a combination of two or more thereof.

18. The oral care composition according to any foregoing claim further comprising: a fluoride source, optionally, in an amount from about 0.1 to about 2 wt.%.

19. The oral care composition according to claim 18, wherein the fluoride source is selected from stannous fluoride, sodium fluoride, potassium fluoride, sodium monofluorophosphate, sodium fluorosilicate, ammonium fluorosilicate, amine fluoride, ammonium fluoride, and a combination of two or more thereof.

20. The oral care composition according to any foregoing claim further comprising: an anionic surfactant, optionally, in an amount from about 0.5 to about 10 wt.%.

21. The oral care composition according to claim 20, wherein the anionic surfactant is selected from ammonium lauryl sulfate, ammonium lauryl ether sulfate, sodium dodecyl sulfate, sodium coco-sulfate, ammonium coco-sulfate, sodium lauryl sulfate, sodium lauryl ether sulfate, and a combination of two or more thereof.

22. The oral care composition according to any foregoing claim further comprising potassium nitrate.

23. The oral care composition according to claim 20, wherein the potassium nitrate is present in an amount from about 0.1 to about 9 wt.%.

24. The oral care composition according to any foregoing claim further comprising a whitening agent.

25. The oral care composition according to claim 24, wherein the peroxide is selected from hydrogen peroxide, lithium peroxide, potassium peroxide, sodium peroxide, magnesium peroxide, calcium peroxide, barium peroxide, alkyl hydrogen peroxides, dialkyl peroxides, alkyl peroxy acids, peroxy esters, diacyl peroxides, benzoyl peroxide, monoperoxyphthalate, and a combination of two or more thereof.

26. A method for enhancing the shine of a tooth, the method comprising: increasing the molar ratio of calcium to carbon on a surface of the tooth using an oral care composition comprising a polymer network formed of at least one of cross linked polyvinylpyrrolidone or ammonium acryloyldimethyltaurate/VP copolymer and insoluble phosphate contained in the polymer network.

27. Use of a dentifrice for enhancing the shine of a tooth by increasing the molar ratio of calcium to carbon on a surface of the tooth, the dentifrice comprising a polymer network formed of at least one of cross linked polyvinylpyrrolidone or ammonium acryloyldimethyltaurate/VP copolymer and insoluble phosphate contained in the polymer network.

28. An oral care composition comprising: from about 0.1 to about 20 wt.% of one or more gelling agent comprising a cross linked polyvinylpyrrolidone, an ammonium acryloyldimethyltaurate/VP copolymer, or a combination of two or more thereof; and from about 1 to about 35 wt.% of one or more abrasive, wherein all weight percentages are based on the total weight of the oral care composition.

29. The oral care composition according to claim 28, wherein the one or more abrasive comprises a silica abrasive.

30. An oral care composition comprising: a polymer network formed from about 0.1 to about 20 wt.% of one or more gelling agent and a fumed silica; and from about 1 to about 35 wt.% of one or more abrasive, wherein all weight percentages are based on the total weight of the oral care composition.

31. The oral care composition according to claim 30, wherein the one or more gelling agents and the fume silica are present in a weight ratio of about 4:1 to about 1 :3.

32. The oral care composition according to claim 30 or claim 31, wherein the one or more gelling agent are selected from a lightly cross-linked polyvinylpyrrolidone, a lightly-crosslinked polyacrylic acid, a lightly cross-linked PVP/PAA, an ammonium acryloyldimethyltaurate/VP copolymer, a crosspolymer-6, a fibril cellulose, and a combination of two or more thereof.

33. The oral care composition according to any one of claim 30 to claim 32, wherein the one or more abrasive comprises silica abrasive, silicate, aluminosilicates, bentonite, zeolite, kaolin, mica, siliceous or diatomaceous earth, pumice, calcium compounds, calcium carbonate, cuttlebone, polycarbonate, silicon carbide, boron carbide, microcrystalline wax, microcrystalline cellulose, dicalcium phosphate, calcium pyrophosphate, dicalcium orthophosphate dihydrate, tricalcium phosphate, calcium polymetaphosphate, calcium carbonate, calcium bicarbonate, or a combination of two or more thereof.

34. The oral care composition according to any one of claim 30 to claim 33, wherein the one or more abrasive is selected from dicalcium phosphate, calcium pyrophosphate, dicalcium orthophosphate dihydrate, tricalcium phosphate, calcium polymetaphosphate, calcium carbonate, calcium bicarbonate, and a combination of two or more thereof.

35. The oral care composition according to any foregoing claim, wherein the oral care composition has an enamel polishing potential of about 35% or more.