WO2025132388A3 - Procédé de fabrication de dabrafenib - Google Patents
Procédé de fabrication de dabrafenibInfo
- Publication number
- WO2025132388A3 WO2025132388A3 PCT/EP2024/086844 EP2024086844W WO2025132388A3 WO 2025132388 A3 WO2025132388 A3 WO 2025132388A3 EP 2024086844 W EP2024086844 W EP 2024086844W WO 2025132388 A3 WO2025132388 A3 WO 2025132388A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- dabrafenib
- making
- solvate
- salt
- compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
L'invention concerne un procédé de préparation de Dabrafenib, d'un composé de formule (1) ou d'un sel ou d'un solvate de celui-ci :
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP23219444.9 | 2023-12-21 | ||
| EP23219444 | 2023-12-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2025132388A2 WO2025132388A2 (fr) | 2025-06-26 |
| WO2025132388A3 true WO2025132388A3 (fr) | 2025-10-23 |
Family
ID=89321901
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/EP2024/086844 Pending WO2025132388A2 (fr) | 2023-12-21 | 2024-12-17 | Procédé de fabrication de dabrafenib |
Country Status (1)
| Country | Link |
|---|---|
| WO (1) | WO2025132388A2 (fr) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009137391A2 (fr) * | 2008-05-06 | 2009-11-12 | Smithkline Beecham Corporation | Composés de benzène sulfonamide thiazole et oxazole |
| US9884856B2 (en) * | 2013-07-08 | 2018-02-06 | Hangzhou Pushai Pharmaceutical Technology Co., Ltd. | Crystal form of Dabrafenib mesylate and preparation method thereof |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103588767B (zh) | 2013-11-20 | 2016-01-20 | 苏州明锐医药科技有限公司 | 达拉菲尼的制备方法 |
| WO2016059548A1 (fr) | 2014-10-13 | 2016-04-21 | Mylan Laboratories Ltd | Procédés de préparation de dabrafénib |
| US20240383863A1 (en) | 2021-09-17 | 2024-11-21 | Institute For Basic Science | Preparation method for pyrimidine-2-amine |
-
2024
- 2024-12-17 WO PCT/EP2024/086844 patent/WO2025132388A2/fr active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2009137391A2 (fr) * | 2008-05-06 | 2009-11-12 | Smithkline Beecham Corporation | Composés de benzène sulfonamide thiazole et oxazole |
| US9884856B2 (en) * | 2013-07-08 | 2018-02-06 | Hangzhou Pushai Pharmaceutical Technology Co., Ltd. | Crystal form of Dabrafenib mesylate and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2025132388A2 (fr) | 2025-06-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 121 | Ep: the epo has been informed by wipo that ep was designated in this application |
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