WO2025116139A1 - Near-infrared and ultrasound fusion stimulator for muscle strengthening - Google Patents
Near-infrared and ultrasound fusion stimulator for muscle strengthening Download PDFInfo
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- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0626—Monitoring, verifying, controlling systems and methods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
- A61N2005/0652—Arrays of diodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0659—Radiation therapy using light characterised by the wavelength of light used infrared
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0047—Ultrasound therapy interstitial
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N7/00—Ultrasound therapy
- A61N2007/0078—Ultrasound therapy with multiple treatment transducers
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- the present invention relates to a near-infrared and ultrasound fusion stimulator for muscle strengthening, and more specifically, to a near-infrared and ultrasound fusion stimulator for preventing and alleviating muscle loss.
- the world is rapidly aging, and Korea is currently experiencing the fastest aging rate in the world, with the country expected to enter a super-aged society in 2026, with the population aged 65 and over exceeding 20%.
- Sarcopenia is a disease in which muscle mass decreases with aging.
- the prevalence rate among people in their 60s is over 40%, and it is rapidly increasing as the population ages.
- Senile sarcopenia causes falls and physical dysfunction due to a decrease in skeletal muscle mass, and secondarily causes metabolic diseases, obesity, diabetes, and osteopenia.
- the risk of death was 4.1 times higher in men with insufficient muscle mass and strength, and the risk of death was up to 9.5 times higher in those with slow walking speeds (Source: Professor Im Soo-kyo, Department of Endocrinology, Seoul National University Bundang Hospital, a study that followed 565 Koreans over 65 years for 6 years: Public Library of Science 2016).
- the present invention has been made to solve the aforementioned problems, and the near-infrared and ultrasound fusion stimulator for muscle strengthening according to the present invention is intended to provide non-invasive stimulation to muscles to delay muscle loss and promote regeneration, and to prevent and alleviate muscle loss by integrating near-infrared wavelengths capable of penetrating into tissue areas and ultrasound stimulation.
- a near-infrared and ultrasound fusion stimulator for muscle strengthening comprises: a body part forming a body of the near-infrared and ultrasound fusion stimulator and having a circular surface formed at one end; a fusion stimulator installed on the circular surface of the body part to provide ultrasound and near-infrared rays; and a control part controlling the provision of ultrasound and near-infrared rays by the fusion stimulator; wherein the fusion stimulator comprises an ultrasound generation module providing ultrasound; and a near-infrared LED providing near-infrared rays.
- a plurality of the ultrasonic generating modules may be arranged at regular intervals on the circular surface of the body portion, and a plurality of the near-infrared LEDs may be arranged between and around the plurality of the ultrasonic generating modules arranged at regular intervals on the circular surface of the body portion.
- a plurality of the ultrasonic generating modules are formed with a step so as to protrude more than the near-infrared LED from the circular surface of the body, and the plurality of the near-infrared LEDs can irradiate and provide near-infrared rays in a space formed by the step between the plurality of the ultrasonic generating modules in the circular surface of the body.
- a plurality of the ultrasonic generating modules are formed in a fan shape on the circular surface of the body, and a plurality of the near-infrared LEDs are arranged in the space between and around the plurality of the ultrasonic generating modules on the circular surface of the body to provide near-infrared rays.
- the present invention may further include a band portion that connects a plurality of the ultrasonic generating modules to each other.
- the ultrasonic generation module may be arranged at the center of the circular surface of the body portion, and a plurality of near-infrared LEDs may be arranged around the ultrasonic generation module.
- a plurality of the near-infrared LEDs may be arranged in a ring at equal intervals around the ultrasonic generating module.
- the ultrasonic generation module generates and provides ultrasonic waves of 1 MHz, and the near-infrared LED can provide near-infrared rays of 850 nm or 1050 nm.
- the near-infrared and ultrasound fusion stimulator for muscle strengthening according to the present invention is intended to provide non-invasive stimulation to muscles to delay muscle loss and promote regeneration, and can prevent and alleviate muscle loss by integrating near-infrared wavelengths capable of penetrating into tissue areas and ultrasound stimulation.
- FIG. 1 is a configuration diagram of a near-infrared and ultrasound fusion stimulator for muscle strengthening according to one embodiment of the present invention.
- FIG. 2 is a drawing for explaining a near-infrared and ultrasound fusion stimulator for muscle strengthening according to one embodiment of the present invention.
- FIG. 3 is a drawing for explaining a near-infrared and ultrasound fusion stimulator for muscle strengthening according to another embodiment of the present invention.
- FIG. 4 is a drawing for explaining a near-infrared and ultrasound fusion stimulator for muscle strengthening according to another embodiment of the present invention.
- FIGS. 5 to 9 are drawings for explaining the effect of a near-infrared and ultrasound fusion stimulator for muscle strengthening according to one embodiment of the present invention.
- FIG. 1 is a configuration diagram of a near-infrared and ultrasound fusion stimulator for muscle strengthening according to one embodiment of the present invention.
- FIG. 2 is a drawing for explaining a near-infrared and ultrasonic fusion stimulator for muscle strengthening according to one embodiment of the present invention
- FIG. 3 is a drawing for explaining a near-infrared and ultrasonic fusion stimulator for muscle strengthening according to another embodiment of the present invention
- FIG. 4 is a drawing for explaining a near-infrared and ultrasonic fusion stimulator for muscle strengthening according to another embodiment of the present invention.
- FIGS. 1 to 4 a near-infrared and ultrasound fusion stimulator for muscle strengthening according to the present invention will be described with reference to FIGS. 1 to 4.
- a near-infrared and ultrasound fusion stimulator (100) for muscle strengthening comprises a body part (101), a fusion stimulator part (110), and a control part (120).
- the above body part (101) constitutes the body of a near-infrared and ultrasonic fusion stimulator (100), and a circular surface is formed at one end of the body part (101).
- the fusion stimulation unit (110) is installed on a circular surface of the end of the body unit (101) to provide ultrasonic waves and near-infrared rays, and the control unit (120) controls the provision of ultrasonic waves and near-infrared rays by the fusion stimulation unit (110).
- the fusion stimulation unit (110) may be configured to include an ultrasonic generation module (111) that provides ultrasonic waves and a near-infrared LED (112) that provides near-infrared rays.
- the ultrasonic generation module (111) may generate and provide ultrasonic waves of 1 MHz
- the near-infrared LED (112) may provide near-infrared rays of 850 nm or 1050 nm.
- the ultrasonic generation modules (111) are arranged at regular intervals on one circular surface of the body portion (101), and the near-infrared LED (112) can be arranged between and around a plurality of the ultrasonic generation modules (111) arranged at regular intervals on the circular surface of the body portion (101).
- a plurality of ultrasonic generation modules (111) may be formed with a step so as to protrude more than the near-infrared LED (112) from the circular surface of the body part (101).
- the near-infrared LED (112) can irradiate and provide near-infrared rays from the inside of the space formed by the step between the plurality of ultrasonic generating modules (111) on the circular surface of the body part (101).
- a plurality of ultrasonic generating modules (111) may be formed in a fan shape on the circular surface of the body part (101).
- a plurality of near-infrared LEDs (112) can be arranged in the space between and around a plurality of ultrasonic generation modules (111) on the circular surface of the body part (101) to provide near-infrared rays.
- a plurality of ultrasonic wave generating modules (111) such as in (c) of Fig. 3 can be connected to each other using a band part (113) such as in (a) of Fig. 3.
- the ultrasonic generation module (111) may be placed at the center of one end of the circular surface of the body part (101), and a plurality of near-infrared LEDs (112) may be placed around the ultrasonic generation module (111).
- a plurality of the near-infrared LEDs (112) can be arranged in a ring shape at even intervals around the ultrasonic generation module (111).
- FIGS. 5 to 9 are drawings for explaining the effect of a near-infrared and ultrasound fusion stimulator for muscle strengthening according to one embodiment of the present invention.
- FIG. 5 is a graph for explaining the effect of promoting muscle cell regeneration according to light irradiation at various energies of near-infrared wavelengths according to one embodiment of the present invention.
- a near-infrared and ultrasound fusion stimulator irradiates muscle cells with near-infrared light of 850 nm or 1050 nm for 3 days, it can be seen that MHC expression is relatively promoted compared to when the near-infrared light is not irradiated, in the case of L6 cell differentiation in Fig. 5 (a) and in the case of C2C12 cell differentiation in Fig. 5 (b).
- FIG. 6 is a graph for explaining the effect of promoting muscle cell differentiation by near-infrared wavelength light irradiation and ultrasound fusion stimulation according to one embodiment of the present invention.
- a near-infrared and ultrasound fusion stimulator irradiates muscle cells with near-infrared light of 850 nm or 1050 nm and ultrasound together, it can be seen that MHC expression is relatively promoted when compared to when near-infrared light is not irradiated and when only near-infrared light is irradiated, during L6 cell differentiation in Fig. 6 (a) and during C2C12 cell differentiation in Fig. 6 (b).
- FIG. 7 is a graph for explaining the effect of promoting muscle cell regeneration according to light irradiation at various energies of near-infrared wavelengths according to one embodiment of the present invention.
- Fig. 7 (a) is a drawing showing the differentiation of L6 of muscle cells before
- Fig. 7 (b) is a drawing showing the differentiation of L6 when not irradiated with near-infrared light
- Fig. 7 (c) is a drawing showing the differentiation of L6 when irradiated with near-infrared light of 850 nm
- Fig. 7 (d) is a drawing showing the differentiation of L6 when irradiated with near-infrared light of 1050 nm.
- Fig. 7 (e) is a drawing showing the differentiation of C2C12 muscle cells before
- Fig. 7 (f) is a drawing showing the differentiation of C2C12 when not irradiated with near-infrared light
- Fig. 7 (g) is a drawing showing the differentiation of C2C12 when irradiated with near-infrared light of 850 nm
- Fig. 7 (h) is a drawing showing the differentiation of C2C12 when irradiated with near-infrared light of 1050 nm.
- FIG. 8 is a graph for explaining whether human dural fibroblasts are cytotoxic according to LED wavelength (630 nm, 850 nm, 1050 nm) and energy of a near-infrared and ultrasound fusion stimulator for muscle strengthening according to an embodiment of the present invention
- FIG. 9 is a graph for explaining whether human dural fibroblasts are cytotoxic according to ultrasound stimulation of a near-infrared and ultrasound fusion stimulator for muscle strengthening according to an embodiment of the present invention.
- the near-infrared and ultrasound fusion stimulator for muscle strengthening is intended to provide non-invasive stimulation to muscles to delay muscle loss and promote regeneration, and can prevent and alleviate muscle loss by integrating near-infrared wavelengths capable of penetrating into tissue areas and ultrasound stimulation.
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Abstract
Description
본 발명은 근육 강화를 위한 근적외선 및 초음파 융합 자극기에 관한 것으로, 보다 상세하게는 근감소를 예방하고 완화하는 근적외선 및 초음파 융합 자극기에 관한 것이다.The present invention relates to a near-infrared and ultrasound fusion stimulator for muscle strengthening, and more specifically, to a near-infrared and ultrasound fusion stimulator for preventing and alleviating muscle loss.
세계적으로 급속하게 고령화가 진행되고 있으며, 현재 우리나라의 고령화 속도는 세계 최고수준으로, 2026년 65세 노인인구가 20%를 넘는 초고령사회에 진입할 예정이다.The world is rapidly aging, and Korea is currently experiencing the fastest aging rate in the world, with the country expected to enter a super-aged society in 2026, with the population aged 65 and over exceeding 20%.
고령화로 인한 국가 잠재성장률의 지속적인 하락과 국가 의료비 지출이 상승하고 있으며, 그에 따라 고령화에 따른 인지, 근골격계 등 신체기능 저하를 조기 발견하여 이를 관리함으로써 노화를 지연시킬 필요성 대두되고 있다.As the national potential growth rate continues to decline and national medical expenses increase due to the aging population, the need to delay aging by early detection and management of declines in cognitive, musculoskeletal, and other physical functions due to aging is emerging.
노인성 근감소증(Sarcopenia)은 노화가 진행되면서 근육이 감소하는 질환으로 60대의 유병률이 40% 이상으로 인구 고령화에 따라 급속히 증가하는 추세이다.Sarcopenia is a disease in which muscle mass decreases with aging. The prevalence rate among people in their 60s is over 40%, and it is rapidly increasing as the population ages.
노인성 근감소증은 골격근의 감소로 인해 낙상 및 신체기능 장애를 유발하고, 이차적으로 대사질환, 비만, 당뇨, 골감소증 등을 유발하고 있다. 65세 이상 노인들을 6년 간 추적 관찰한 결과, 근육량과 근력이 부족한 남성의 경우 사망 위험률은 4.1배 높았고, 보행 속도까지 느린 경우엔 사망 위험률이 9.5배까지 높아졌다(출처: 분당서울대병원 내분비내고하 임수교수님, 65세 이상 한국인 565명 6년간 추적한 연구: Public Library of Science 2016).Senile sarcopenia causes falls and physical dysfunction due to a decrease in skeletal muscle mass, and secondarily causes metabolic diseases, obesity, diabetes, and osteopenia. As a result of a 6-year follow-up observation of the elderly over 65 years, the risk of death was 4.1 times higher in men with insufficient muscle mass and strength, and the risk of death was up to 9.5 times higher in those with slow walking speeds (Source: Professor Im Soo-kyo, Department of Endocrinology, Seoul National University Bundang Hospital, a study that followed 565 Koreans over 65 years for 6 years: Public Library of Science 2016).
그러나, 현재 노화성 근감소증에 대한 국내외 연구는 아직 초기 단계로, 근력운동과 단백질 섭취의 식이요법 외에는 별다른 예방 및 치료책이 전무한 실정이다.However, domestic and international research on age-related sarcopenia is still in its initial stages, and there are no preventive or therapeutic measures other than strength training and dietary protein intake.
본 발명은 전술한 문제를 해결하기 위해 안출된 것으로서, 본 발명에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기는 근육 감소를 지연시키고, 재생을 촉진하기 위한 근육에 비침습자극을 주기 위한 것으로, 조직부위까지 침투가 가능한 근적외선 파장과 초음파 자극을 융합하여 근감소를 예방 및 완화하고자 한다.The present invention has been made to solve the aforementioned problems, and the near-infrared and ultrasound fusion stimulator for muscle strengthening according to the present invention is intended to provide non-invasive stimulation to muscles to delay muscle loss and promote regeneration, and to prevent and alleviate muscle loss by integrating near-infrared wavelengths capable of penetrating into tissue areas and ultrasound stimulation.
전술한 문제를 해결하기 위한 본 발명의 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기는, 상기 근적외선 및 초음파 융합 자극기의 몸체를 구성하고, 일단에 원형면이 형성되는 몸체부; 상기 몸체부의 원형면에 설치되어, 초음파와 근적외선을 제공하는 융합 자극부; 및 상기 융합 자극부의 초음파와 근적외선의 제공을 제어하는 제어부;를 포함하고, 상기 융합 자극부는 초음파를 제공하는 초음파 발생 모듈; 및 근적외선을 제공하는 근적외선 LED;를 포함하여 구성된다.According to one embodiment of the present invention for solving the above-described problem, a near-infrared and ultrasound fusion stimulator for muscle strengthening comprises: a body part forming a body of the near-infrared and ultrasound fusion stimulator and having a circular surface formed at one end; a fusion stimulator installed on the circular surface of the body part to provide ultrasound and near-infrared rays; and a control part controlling the provision of ultrasound and near-infrared rays by the fusion stimulator; wherein the fusion stimulator comprises an ultrasound generation module providing ultrasound; and a near-infrared LED providing near-infrared rays.
본 발명의 다른 일실시예에 따르면, 복수개의 상기 초음파 발생 모듈은 상기 몸체부의 원형면에 일정 간격으로 배치되고, 복수개의 상기 근적외선 LED는 상기 몸체부의 원형면에서, 일정 간격으로 배치된 복수개의 상기 초음파 발생 모듈의 사이와 주변에 배치될 수 있다.According to another embodiment of the present invention, a plurality of the ultrasonic generating modules may be arranged at regular intervals on the circular surface of the body portion, and a plurality of the near-infrared LEDs may be arranged between and around the plurality of the ultrasonic generating modules arranged at regular intervals on the circular surface of the body portion.
본 발명의 다른 일실시예에 따르면, 복수개의 상기 초음파 발생 모듈은 상기 몸체부의 원형면에서 상기 근적외선 LED 보다 돌출되도록 단차가 형성되고, 복수개의 상기 근적외선 LED는 상기 몸체부의 원형면에서, 복수개의 상기 초음파 발생 모듈의 사이의 상기 단차에 의해 형성되는 공간에서 근적외선을 조사하여 제공할 수 있다.According to another embodiment of the present invention, a plurality of the ultrasonic generating modules are formed with a step so as to protrude more than the near-infrared LED from the circular surface of the body, and the plurality of the near-infrared LEDs can irradiate and provide near-infrared rays in a space formed by the step between the plurality of the ultrasonic generating modules in the circular surface of the body.
본 발명의 다른 일실시예에 따르면, 복수개의 상기 초음파 발생 모듈은 상기 몸체부의 원형면에서, 각각 부채꼴 형태로 형성되고, 복수개의 상기 근적외선 LED는 상기 몸체부의 원형면에서 복수개의 상기 초음파 발생 모듈들 간의 공간과 주변에 배치되어 근적외선을 제공할 수 있다.According to another embodiment of the present invention, a plurality of the ultrasonic generating modules are formed in a fan shape on the circular surface of the body, and a plurality of the near-infrared LEDs are arranged in the space between and around the plurality of the ultrasonic generating modules on the circular surface of the body to provide near-infrared rays.
본 발명의 다른 일실시예에 따르면, 복수개의 상기 초음파 발생 모듈을 상호 묶는 밴드부;를 더 포함하여 구성될 수 있다.According to another embodiment of the present invention, the present invention may further include a band portion that connects a plurality of the ultrasonic generating modules to each other.
본 발명의 다른 일실시예에 따르면, 상기 초음파 발생 모듈은 상기 몸체부의 원형면의 중심부에 배치되고, 복수개의 상기 근적외선 LED는 상기 초음파 발생 모듈의 주변에 배치될 수 있다.According to another embodiment of the present invention, the ultrasonic generation module may be arranged at the center of the circular surface of the body portion, and a plurality of near-infrared LEDs may be arranged around the ultrasonic generation module.
본 발명의 다른 일실시예에 따르면, 복수개의 상기 근적외선 LED는 상기 초음파 발생 모듈의 주변에 균일한 간격의 환형으로 배치될 수 있다.According to another embodiment of the present invention, a plurality of the near-infrared LEDs may be arranged in a ring at equal intervals around the ultrasonic generating module.
본 발명의 다른 일실시예에 따르면, 상기 초음파 발생 모듈은 1 MHz의 초음파를 생성하여 제공하고, 상기 근적외선 LED는 850 nm 또는 1050 nm의 근적외선을 제공할 수 있다.According to another embodiment of the present invention, the ultrasonic generation module generates and provides ultrasonic waves of 1 MHz, and the near-infrared LED can provide near-infrared rays of 850 nm or 1050 nm.
본 발명에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기는 근육 감소를 지연시키고, 재생을 촉진하기 위한 근육에 비침습자극을 주기 위한 것으로, 조직부위까지 침투가 가능한 근적외선 파장과 초음파 자극을 융합하여 근감소를 예방 및 완화할 수 있다.The near-infrared and ultrasound fusion stimulator for muscle strengthening according to the present invention is intended to provide non-invasive stimulation to muscles to delay muscle loss and promote regeneration, and can prevent and alleviate muscle loss by integrating near-infrared wavelengths capable of penetrating into tissue areas and ultrasound stimulation.
도 1은 본 발명의 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기의 구성도이다.FIG. 1 is a configuration diagram of a near-infrared and ultrasound fusion stimulator for muscle strengthening according to one embodiment of the present invention.
도 2는 본 발명의 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기를 설명하기 위한 도면이다.FIG. 2 is a drawing for explaining a near-infrared and ultrasound fusion stimulator for muscle strengthening according to one embodiment of the present invention.
도 3은 본 발명의 다른 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기를 설명하기 위한 도면이다.FIG. 3 is a drawing for explaining a near-infrared and ultrasound fusion stimulator for muscle strengthening according to another embodiment of the present invention.
도 4는 본 발명의 다른 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기를 설명하기 위한 도면이다.FIG. 4 is a drawing for explaining a near-infrared and ultrasound fusion stimulator for muscle strengthening according to another embodiment of the present invention.
도 5 내지 도 9는 본 발명의 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기의 효과를 설명하기 위한 도면이다.FIGS. 5 to 9 are drawings for explaining the effect of a near-infrared and ultrasound fusion stimulator for muscle strengthening according to one embodiment of the present invention.
본 발명은 다양한 변환을 가할 수 있고 여러 가지 실시예를 가질 수 있는 바, 특정 실시예들을 도면에 예시하고 상세한 설명에 상세하게 설명하고자 한다. 그러나, 이는 본 발명을 특정한 실시 형태에 대해 한정하려는 것이 아니며, 본 발명의 사상 및 기술 범위에 포함되는 모든 변환, 균등물 내지 대체물을 포함하는 것으로 이해되어야 한다.The present invention can be modified in various ways and has various embodiments, and specific embodiments are illustrated in the drawings and described in detail in the detailed description. However, this is not intended to limit the present invention to specific embodiments, but should be understood to include all modifications, equivalents, or substitutes included in the spirit and technical scope of the present invention.
다만, 실시형태를 설명함에 있어서, 관련된 공지 기능 혹은 구성에 대한 구체적인 설명이 본 발명의 요지를 불필요하게 흐릴 수 있다고 판단되는 경우 그에 대한 상세한 설명은 생략한다. 또한, 도면에서의 각 구성요소들의 크기는 설명을 위하여 과장될 수 있으며, 실제로 적용되는 크기를 의미하는 것은 아니다.However, when describing the embodiments, if it is judged that a specific description of a related known function or configuration may unnecessarily obscure the gist of the present invention, a detailed description thereof will be omitted. In addition, the size of each component in the drawings may be exaggerated for the purpose of description, and does not mean the size actually applied.
또한, 명세서 전체에서, 일 구성요소가 다른 구성요소와 "연결된다" 거나 "접속된다" 등으로 언급된 때에는, 상기 일 구성요소가 상기 다른 구성요소와 직접 연결되거나 또는 직접 접속될 수도 있지만, 특별히 반대되는 기재가 존재하지 않는 이상, 중간에 또 다른 구성요소를 매개하여 연결되거나 또는 접속될 수도 있다고 이해되어야 할 것이다. 또한, 명세서 전체에서, 어떤 부분이 어떤 구성요소를 "포함"한다고 할 때, 이는 특별히 반대되는 기재가 없는 한 다른 구성요소를 제외하는 것이 아니라 다른 구성요소를 더 포함할 수 있는 것을 의미한다.In addition, throughout the specification, when a component is referred to as being "connected" or "connected" to another component, it should be understood that the component may be directly connected or directly connected to the other component, but may also be connected or connected via another component in between, unless otherwise specifically stated. In addition, throughout the specification, when it is said that a part "includes" a component, this does not exclude other components, but rather may include other components, unless otherwise specifically stated.
도 1은 본 발명의 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기의 구성도이다.FIG. 1 is a configuration diagram of a near-infrared and ultrasound fusion stimulator for muscle strengthening according to one embodiment of the present invention.
도 2는 본 발명의 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기를 설명하기 위한 도면이고, 도 3은 본 발명의 다른 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기를 설명하기 위한 도면이고, 도 4는 본 발명의 다른 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기를 설명하기 위한 도면이다.FIG. 2 is a drawing for explaining a near-infrared and ultrasonic fusion stimulator for muscle strengthening according to one embodiment of the present invention, FIG. 3 is a drawing for explaining a near-infrared and ultrasonic fusion stimulator for muscle strengthening according to another embodiment of the present invention, and FIG. 4 is a drawing for explaining a near-infrared and ultrasonic fusion stimulator for muscle strengthening according to another embodiment of the present invention.
이후부터는 도 1 내지 도 4를 참조하여 본 발명에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기를 설명하기로 한다.Hereinafter, a near-infrared and ultrasound fusion stimulator for muscle strengthening according to the present invention will be described with reference to FIGS. 1 to 4.
본 발명의 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기(100)는 몸체부(101), 융합 자극부(110) 및 제어부(120)를 포함하여 구성된다.A near-infrared and ultrasound fusion stimulator (100) for muscle strengthening according to one embodiment of the present invention comprises a body part (101), a fusion stimulator part (110), and a control part (120).
상기 몸체부(101)는 근적외선 및 초음파 융합 자극기(100)의 몸체를 구성하며, 상기 몸체부(101)의 일단에는 원형면이 형성된다.The above body part (101) constitutes the body of a near-infrared and ultrasonic fusion stimulator (100), and a circular surface is formed at one end of the body part (101).
또한, 상기 융합 자극부(110)는 상기 몸체부(101)의 단부의 원형면에 설치되어, 초음파와 근적외선을 제공하며, 상기 제어부(120)는 상기 융합 자극부(110)의 초음파와 근적외선의 제공을 제어한다.In addition, the fusion stimulation unit (110) is installed on a circular surface of the end of the body unit (101) to provide ultrasonic waves and near-infrared rays, and the control unit (120) controls the provision of ultrasonic waves and near-infrared rays by the fusion stimulation unit (110).
이때, 상기 융합 자극부(110)는 초음파를 제공하는 초음파 발생 모듈(111) 및 근적외선을 제공하는 근적외선 LED(112)를 포함하여 구성될 수 있으며, 본 발명의 일실시예에 따르면, 상기 초음파 발생 모듈(111)은 1 MHz의 초음파를 생성하여 제공하고, 상기 근적외선 LED(112)는 850 nm 또는 1050 nm의 근적외선을 제공할 수 있다.At this time, the fusion stimulation unit (110) may be configured to include an ultrasonic generation module (111) that provides ultrasonic waves and a near-infrared LED (112) that provides near-infrared rays. According to one embodiment of the present invention, the ultrasonic generation module (111) may generate and provide ultrasonic waves of 1 MHz, and the near-infrared LED (112) may provide near-infrared rays of 850 nm or 1050 nm.
보다 구체적으로, 도 2의 (a)와 (b)를 참조하면 상기 초음파 발생 모듈(111)은 상기 몸체부(101)의 일단의 원형면에 일정 간격으로 배치되며, 상기 근적외선 LED(112)는 상기 몸체부(101)의 원형면 상에서 일정 간격으로 배치되는 복수개의 상기 초음파 발생 모듈(111)의 사이와 주변에 배치될 수 있다.More specifically, referring to (a) and (b) of FIG. 2, the ultrasonic generation modules (111) are arranged at regular intervals on one circular surface of the body portion (101), and the near-infrared LED (112) can be arranged between and around a plurality of the ultrasonic generation modules (111) arranged at regular intervals on the circular surface of the body portion (101).
또한, 도 2의 (c)를 참조하면 복수개의 상기 초음파 발생 모듈(111)은 상기 몸체부(101)의 원형면에서, 상기 근적외선 LED(112) 보다 돌출되도록 단차가 형성될 수 있다.In addition, referring to (c) of Fig. 2, a plurality of ultrasonic generation modules (111) may be formed with a step so as to protrude more than the near-infrared LED (112) from the circular surface of the body part (101).
따라서, 상기 근적외선 LED(112)는 상기 몸체부(101)의 원형면 상에서, 복수개의 상기 초음파 발생 모듈(111)의 사이의 상기 단차에 의해 형성되는 공간의 내측에서 근적외선을 조사하여 제공할 수 있다.Accordingly, the near-infrared LED (112) can irradiate and provide near-infrared rays from the inside of the space formed by the step between the plurality of ultrasonic generating modules (111) on the circular surface of the body part (101).
본 발명의 또 다른 일실시예에 따르면, 도 3의 (a)와 (b)에서와 같이 같이 복수개의 상기 초음파 발생 모듈(111)은 상기 몸체부(101)의 원형면 상에서, 각각 부채꼴 형태로 형성될 수 있다.According to another embodiment of the present invention, as shown in (a) and (b) of FIG. 3, a plurality of ultrasonic generating modules (111) may be formed in a fan shape on the circular surface of the body part (101).
또한, 복수개의 상기 근적외선 LED(112)는 상기 몸체부(101)의 원형면에서, 복수개의 상기 초음파 발생 모듈(111)들 간의 공간과 주변에 배치되어 근적외선을 제공할 수 있다.In addition, a plurality of near-infrared LEDs (112) can be arranged in the space between and around a plurality of ultrasonic generation modules (111) on the circular surface of the body part (101) to provide near-infrared rays.
한편, 도 3의 (c)에서와 같은 복수개의 상기 초음파 발생 모듈(111)을 도 3의 (a)에서와 같이 밴드부(113)를 이용하여 상호간에 하나로 묶을 수 있다.Meanwhile, a plurality of ultrasonic wave generating modules (111) such as in (c) of Fig. 3 can be connected to each other using a band part (113) such as in (a) of Fig. 3.
또한, 도 4의 (a)와 (b)를 참조하면, 상기 초음파 발생 모듈(111)은 상기 몸체부(101)의 일단의 원형면의 중심부에 배치되고, 복수개의 상기 근적외선 LED(112)는 상기 초음파 발생 모듈(111)의 주변에 배치될 수 있다.In addition, referring to (a) and (b) of FIG. 4, the ultrasonic generation module (111) may be placed at the center of one end of the circular surface of the body part (101), and a plurality of near-infrared LEDs (112) may be placed around the ultrasonic generation module (111).
보다 상세하게 설명하면, 복수개의 상기 근적외선 LED(112)는 상기 초음파 발생 모듈(111)의 주변에 균일한 간격의 환형으로 배치될 수 있다.To explain in more detail, a plurality of the near-infrared LEDs (112) can be arranged in a ring shape at even intervals around the ultrasonic generation module (111).
도 5 내지 도 9는 본 발명의 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기의 효과를 설명하기 위한 도면이다.FIGS. 5 to 9 are drawings for explaining the effect of a near-infrared and ultrasound fusion stimulator for muscle strengthening according to one embodiment of the present invention.
보다 구체적으로 설명하면, 도 5는 본 발명의 일실시예에 따른 근적외선 파장의 다양한 에너지별 광조사에 따른 근육세포 재생 촉진 효과를 설명하기 위한 그래프이다.More specifically, FIG. 5 is a graph for explaining the effect of promoting muscle cell regeneration according to light irradiation at various energies of near-infrared wavelengths according to one embodiment of the present invention.
본 발명의 일실시에에 따른 근적외선 및 초음파 융합 자극기가 근육세포에 850 nm 또는 1050 nm의 근적외선 광을 3일간 조사한 경우, 도 5의 (a)의 L6 세포 분화시와 도 5의 (b)의 C2C12 세포 분화시, 근적외선 광을 조사하지 않았을 때와 비교하여, MHC 발현이 상대적으로 촉진됨을 알 수 있다. When a near-infrared and ultrasound fusion stimulator according to one embodiment of the present invention irradiates muscle cells with near-infrared light of 850 nm or 1050 nm for 3 days, it can be seen that MHC expression is relatively promoted compared to when the near-infrared light is not irradiated, in the case of L6 cell differentiation in Fig. 5 (a) and in the case of C2C12 cell differentiation in Fig. 5 (b).
이를 통해 근육을 구성하는 근육세포의 분화하는 과정동안, 근적외선 LED 파장의 다양한 에너지별 조사에 따른 근육세포 분화의 정도가 촉진됨을 알 수 있다.Through this, it can be seen that during the differentiation process of muscle cells that constitute the muscles, the degree of muscle cell differentiation is promoted according to irradiation with various energies of near-infrared LED wavelengths.
보다 상세하게는, 도 6은 본 발명의 일실시예에 따른 근적외선 파장 광조사와 초음파 융합 자극에 따른 근육세포 분화 촉진 효과를 설명하기 위한 그래프이다.More specifically, FIG. 6 is a graph for explaining the effect of promoting muscle cell differentiation by near-infrared wavelength light irradiation and ultrasound fusion stimulation according to one embodiment of the present invention.
본 발명의 일실시에에 따른 근적외선 및 초음파 융합 자극기가 근육세포에 850 nm 또는 1050 nm의 근적외선 광과 초음파를 함께 조사한 경우, 도 6의 (a)의 L6 세포 분화시와 도 6의 (b)의 C2C12 세포 분화시, 근적외선 광을 조사하지 않았을 때 및 근적외선 광만 조사하였을 때와 비교하여, MHC 발현이 상대적으로 촉진됨을 알 수 있다.According to one embodiment of the present invention, when a near-infrared and ultrasound fusion stimulator irradiates muscle cells with near-infrared light of 850 nm or 1050 nm and ultrasound together, it can be seen that MHC expression is relatively promoted when compared to when near-infrared light is not irradiated and when only near-infrared light is irradiated, during L6 cell differentiation in Fig. 6 (a) and during C2C12 cell differentiation in Fig. 6 (b).
이를 통해, 근육을 구성하는 근육세포의 분화하는 과정동안, 근적외선 LED 파장과 초음파 융합 자극 후, 근육세포 분화의 정도가 촉진됨을 알 수 있다.Through this, it can be seen that during the differentiation process of muscle cells that constitute the muscle, the degree of muscle cell differentiation is promoted after stimulation with a fusion of near-infrared LED wavelength and ultrasound.
도 7은 본 발명의 일실시예에 따른 본 발명의 일실시예에 따른 근적외선 파장의 다양한 에너지별 광조사에 따른 근육세포 재생 촉진 효과를 설명하기 위한 그래프이다.FIG. 7 is a graph for explaining the effect of promoting muscle cell regeneration according to light irradiation at various energies of near-infrared wavelengths according to one embodiment of the present invention.
보다 상세하게 설명하면, 도 7의 (a)는 근육세포의 L6의 분화전을 도시한 도면이고, 도 7의 (b)는 근적외선 광을 조사하지 않은 경우의 L6의 분화후를 도시한 도면이고, 도 7의 (c)는 850 nm의 근적외선 광을 조사한 경우의 L6의 분화후를 도시한 도면이고, 도 7의 (d)는 1050 nm의 근적외선 광을 조사한 경우의 L6의 분화후를 도시한 도면이다.To explain in more detail, Fig. 7 (a) is a drawing showing the differentiation of L6 of muscle cells before, Fig. 7 (b) is a drawing showing the differentiation of L6 when not irradiated with near-infrared light, Fig. 7 (c) is a drawing showing the differentiation of L6 when irradiated with near-infrared light of 850 nm, and Fig. 7 (d) is a drawing showing the differentiation of L6 when irradiated with near-infrared light of 1050 nm.
또한, 도 7의 (e)는 근육세포의 C2C12의 분화전을 도시한 도면이고, 도 7의 (f)는 근적외선 광을 조사하지 않은 경우의 C2C12의 분화후를 도시한 도면이고, 도 7의 (g)는 850 nm의 근적외선 광을 조사한 경우의 C2C12의 분화후를 도시한 도면이고, 도 7의 (h)는 1050 nm의 근적외선 광을 조사한 경우의 C2C12의 분화후를 도시한 도면이다.In addition, Fig. 7 (e) is a drawing showing the differentiation of C2C12 muscle cells before, Fig. 7 (f) is a drawing showing the differentiation of C2C12 when not irradiated with near-infrared light, Fig. 7 (g) is a drawing showing the differentiation of C2C12 when irradiated with near-infrared light of 850 nm, and Fig. 7 (h) is a drawing showing the differentiation of C2C12 when irradiated with near-infrared light of 1050 nm.
따라서, 근적외선 LED 파장의 광조사시, 근육세포 분화가 촉진되어 Geimsa 염색을 통하여 마이크로튜블(microtubules) 형태가 증가함을 확인할 수 있다.Therefore, when irradiated with near-infrared LED wavelength light, muscle cell differentiation is promoted, and it can be confirmed through Geimsa staining that the microtubules form increases.
도 8은 본 발명의 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기의 LED 파장(630 nm, 850 nm, 1050 nm) 및 에너지별 인간 경막 섬유아세포(human dural fibroblast)의 세포 독성 여부를 설명하기 위한 그래프이고, 도 9는 본 발명의 일실시예에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기의 초음파 자극에 따른 인간 경막 섬유아세포(human dural fibroblast)의 세포 독성 여부를 설명하기 위한 그래프이다.FIG. 8 is a graph for explaining whether human dural fibroblasts are cytotoxic according to LED wavelength (630 nm, 850 nm, 1050 nm) and energy of a near-infrared and ultrasound fusion stimulator for muscle strengthening according to an embodiment of the present invention, and FIG. 9 is a graph for explaining whether human dural fibroblasts are cytotoxic according to ultrasound stimulation of a near-infrared and ultrasound fusion stimulator for muscle strengthening according to an embodiment of the present invention.
도 8에서와 같이 LPS 처리후 1050 nm의 근적외선의 광조사 시와, 도 9에서와 같이 LPS 처리후 초음파의 제공 시에, 인간 경막 섬유아세포(human dural fibroblast)의 세포 독성에는 문제가 없음을 알 수 있다.As shown in Fig. 8, it can be seen that there is no problem with the cytotoxicity of human dural fibroblasts when irradiated with near-infrared light at 1050 nm after LPS treatment, and when provided with ultrasound after LPS treatment, as shown in Fig. 9.
이와 같이, 본 발명에 따른 근육 강화를 위한 근적외선 및 초음파 융합 자극기는 근육 감소를 지연시키고, 재생을 촉진하기 위한 근육에 비침습자극을 주기 위한 것으로, 조직부위까지 침투가 가능한 근적외선 파장과 초음파 자극을 융합하여 근감소를 예방 및 완화할 수 있다.In this way, the near-infrared and ultrasound fusion stimulator for muscle strengthening according to the present invention is intended to provide non-invasive stimulation to muscles to delay muscle loss and promote regeneration, and can prevent and alleviate muscle loss by integrating near-infrared wavelengths capable of penetrating into tissue areas and ultrasound stimulation.
전술한 바와 같은 본 발명의 상세한 설명에서는 구체적인 실시예에 관해 설명하였다. 그러나 본 발명의 범주에서 벗어나지 않는 한도 내에서는 여러 가지 변형이 가능하다. 본 발명의 기술적 사상은 본 발명의 전술한 실시예에 국한되어 정해져서는 안 되며, 청구범위뿐만 아니라 이 청구범위와 균등한 것들에 의해 정해져야 한다.In the detailed description of the present invention as described above, specific embodiments have been described. However, various modifications are possible within the scope of the present invention. The technical idea of the present invention should not be limited to the above-described embodiments of the present invention, but should be determined not only by the claims but also by the equivalents of the claims.
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| KR101384008B1 (en) * | 2013-10-07 | 2014-04-10 | 최소영 | Hand-held type multiple function skin care |
| US20190159761A1 (en) * | 2016-08-02 | 2019-05-30 | Koninklijke Philips N.V. | Surface compliant ultrasound transducer array |
| KR20220000119U (en) * | 2020-07-03 | 2022-01-11 | 가부시키가이샤 아데랑스 | Face and body care device |
| KR20230081274A (en) * | 2021-11-30 | 2023-06-07 | 이승찬 | Growthplate stimulation apparatus |
| CN116764093A (en) * | 2023-07-06 | 2023-09-19 | 深圳市安特贝尔科技有限公司 | Multi-muscle group local vibration muscle stimulation treatment device and control method thereof |
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| KR101384008B1 (en) * | 2013-10-07 | 2014-04-10 | 최소영 | Hand-held type multiple function skin care |
| US20190159761A1 (en) * | 2016-08-02 | 2019-05-30 | Koninklijke Philips N.V. | Surface compliant ultrasound transducer array |
| KR20220000119U (en) * | 2020-07-03 | 2022-01-11 | 가부시키가이샤 아데랑스 | Face and body care device |
| KR20230081274A (en) * | 2021-11-30 | 2023-06-07 | 이승찬 | Growthplate stimulation apparatus |
| CN116764093A (en) * | 2023-07-06 | 2023-09-19 | 深圳市安特贝尔科技有限公司 | Multi-muscle group local vibration muscle stimulation treatment device and control method thereof |
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