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WO2025196581A1 - Composition cosmétique contenant des particules d'amidon à morphologie contrôlée et procédés d'obtention desdites particules - Google Patents

Composition cosmétique contenant des particules d'amidon à morphologie contrôlée et procédés d'obtention desdites particules

Info

Publication number
WO2025196581A1
WO2025196581A1 PCT/IB2025/052610 IB2025052610W WO2025196581A1 WO 2025196581 A1 WO2025196581 A1 WO 2025196581A1 IB 2025052610 W IB2025052610 W IB 2025052610W WO 2025196581 A1 WO2025196581 A1 WO 2025196581A1
Authority
WO
WIPO (PCT)
Prior art keywords
starch
particles
solution
microparticles
cosmetic composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/IB2025/052610
Other languages
English (en)
Inventor
Gaetano Distefano
Patrizia Valsesia
Sara BETTINELLI
Gabriele Anisia DEPTA
Miriam COLOMBO
Davide PROSPERI
Marco GIUSTRA
Giulia SINESI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intercos Italiana SpA
Intercos SpA
Original Assignee
Intercos Italiana SpA
Intercos SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intercos Italiana SpA, Intercos SpA filed Critical Intercos Italiana SpA
Publication of WO2025196581A1 publication Critical patent/WO2025196581A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/732—Starch; Amylose; Amylopectin; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0216—Solid or semisolid forms
    • A61K8/022—Powders; Compacted Powders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A61K8/025—Explicitly spheroidal or spherical shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A61K8/0254—Platelets; Flakes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0241—Containing particulates characterized by their shape and/or structure
    • A61K8/0279—Porous; Hollow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q1/00—Make-up preparations; Body powders; Preparations for removing make-up
    • A61Q1/12—Face or body powders for grooming, adorning or absorbing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns

Definitions

  • the present invention relates to a cosmetic composition containing starch microparticles having a controlled morphology, suitable for replacing microplastics, which are a common ingredient in many cosmetic products.
  • the invention relates to methods for obtaining said microparticles from native starch, without chemical alterations thereof.
  • Microplastics are defined as fragments less than 5 mm in length and constitute a growing environmental concern, in that they have a significant impact on the environment, in particular on oceans and seas.
  • Cosmetic products like creams, lotions, detergents and personal care products, are important sources releasing microplastics in the environment. Such products can contain microplastics purposefully added to the ingredients thereof.
  • the microplastics used in the cosmetic field comprise microparticles having dimensions of about of 5-25 pm.
  • the microplastics used in the cosmetic field come from different sources and are widely used in order to modulate the properties of cosmetic products.
  • the cosmetic microparticles can be plastic microspheres, used as abrasive and peeling products, e.g. microbeads provided in scrubs and toothpaste, and polymers in the form of powder, used to improve the tactile pleasantness and the optic properties of cosmetic products.
  • microplastics can reach aquatic ecosystems, starting from surface water streams, ultimately causing marine pollution.
  • the release of such materials into oceans generally damages the marine ecosystem.
  • microplastics can seep into soil through leaching by rainwater runoff and accumulate in soil.
  • the microplastics accumulated in soil or dispersed in seas can then enter into the food chain, with potential effects on human health when they are ingested through the consumption of fish and other contaminated organisms. Therefore, the problem of microplastics in consumer products (among which cosmetic products) is an urgent issue in order to protect the environment and human health.
  • Starches are polysaccharides (soluble in hot water but insoluble in cold water) widely used in cosmetic industry for their versatile, beneficial properties for skin and hair.
  • the use of starches in cosmetic products entails many advantages, among which naturality in that they are natural and eco-compatible ingredients, feature that attracts consumers oriented toward natural products; the capability of adsorbing humidity adapting cosmetic products for use in humid climates or in order to control shiny skin; their tolerability by sensitive skins, that allows to prepare cosmetic products suitable for a wide range of skin types; their impalpable texture, which favours their use as an excipient.
  • Starches can absorb humidity, improve the texture of products and provide a soft feeling: due to these properties, starches are precious ingredients in a wide range of skin and hair care products. For their versatility and the ability to form gels, starches are useful in a wide range of industrial and food applications, for use as rheological modifiers when solubilized in aqueous phase. At the same time, when starches are used in particle form, their morphology plays a crucial role in determining their physical and functional properties.
  • lamellar particles are characterized by a gliding feeling to tact and are connoted by marked adhesion to skin, thanks to the interaction between skin surface and the face of each lamella.
  • spherical particles In contrast to lamellar particles, spherical particles have a lower adhesion, but they have a unique tact feeling, thanks to the ball-bearing effect, which allows to get a sophisticated sensoriality. Moreover, such particles have optical properties suitable for obtaining a soft-focus effect.
  • the monodispersity of granulometric distribution is highly desirable for this kind of powders; spherical particles homogeneous in term of dimension enhance the so-called ball-bearing effect and the homogeneity of the soft-focus effect.
  • alpha-amylase on maize starch can lead to different outcomes according to the process conditions.
  • a prolonged action of alpha-amylase at temperatures lower than the gelatinization temperature leads to the formation of superficial pores on starch microparticles, whose depth and number can be modulated according to the process parameters.
  • the exposition to the enzyme over the gelatinization temperature will lead to a progressive diminution of the average molecular weight of starch, with the concomitant production of oligomers and reduction of the viscosity of the solution.
  • Lyophilization is a drying technique providing the removal from water from a frozen sample, through under vacuum sublimation. This technique is commonly used in food industry for producing isolates and extracts under strict thermal control. During the lyophilization technique, the foodstuff is frozen, then water is removed in form of vapour without passing from the liquid state (sublimated). This process allows to preserve very effectively the integrity and the organoleptic properties of the material (e.g. thermolabile materials). Typically, freezing temperatures during lyophilization range -30-50°C https://en.wikipedia.org/wiki/Freeze drying.
  • Spray drying is another drying technique widely used in food and pharmaceutical industry.
  • a solution (or suspension) of starch is atomized into small drops, which are rapidly dried in a hot chamber.
  • the drying speed, temperature and concentration of material can be controlled in order to obtain a wide range of morphologies.
  • starches it is known that more moderate drying conditions can lead to the formation of retrograded starch, while more rapid drying conditions can lead to gelatinized starch.
  • the choice of drying conditions is crucial in order to obtain the desired morphology.
  • starches obtained through the use of freeze-dryers and spray dryers find application in different sectors.
  • lyophilized starches are used in pharmaceutical formulations in order to improve the solubility and the stability of medications, while spray drying allows to obtain pre-gelatinized starches widely used in food industry in order to improve product stability.
  • spray drying allows to obtain pre-gelatinized starches widely used in food industry in order to improve product stability.
  • the properties of starch particles are not exploited to improve the flowability and/or the optical properties of the preparations.
  • Microprecipitation is an advanced technique used to produce microparticles with dimensions in the order of micrometres or nanometres.
  • US 20220265525 Al describes starch-containing particles having an average particle diameter of 0.5 to 20 pm and a maximum particle diameter of less than 30 m, starch containing 90% by weight or more of amylopectin.
  • Such particles may contain an inorganic oxide, wherein the content of starch is 30-90% by weight and the content of the inorganic oxide is 10-70% by weight.
  • the production method of such particles includes an emulsification step of mixing a dispersion liquid of starch, a surfactant, and a nonaqueous solvent to prepare an emulsified liquid containing emulsified droplets; a dehydration step of dehydrating the emulsified droplets; and a step of separating the nonaqueous solvent dispersion body obtained in the dehydration step into solid and liquid to obtain spherical starch particles as solid matter.
  • the emulsified liquid obtained in the emulsification step may be cooled to a range of -50 to 0° C, thereby to use a frozen emulsified liquid in which water in the emulsified droplets is frozen.
  • the sphericity of the particles be 0.85 or more, that is, the particles be spherical.
  • the particles be spherical particles, the rolling properties of cosmetics improve.
  • the sphericity is particularly preferably 0.90 or more.
  • the sphericity was calculated from a photograph of a scanning electron microscope by an image analysis method.
  • WO 2021175775 Al of the same applicant describes the use of native or surface-treated native starches, wherein the use of starches of unusual vegetal origin, like ginger, mung bean, amaranth, white turmeric, Chinese taro, cowherb allows to obtain starch particles having morphologies that have advantageous properties when used in cosmetic compositions.
  • the examples of surface treatment are coatings with silicones, oils, waxes, silica (physical) or reactive silanes (chemical).
  • Porous starch is used in the areas of food, agriculture, pharmaceuticals, and cosmetics as protection for oxidization-labile substances and haemostatic agents, as an adsorbent for heavy metal ions, and as a novel delivery system for poorly water-soluble drugs.
  • WO 2021144245 Al describes the use of native and/or porous starch as white pigment in dental health products and in particular in toothpastes.
  • the native starch is not gelatinized but is under granular form.
  • Porous starch is a granular starch that has been hydrolysed by one or multiple amylolytic enzymes until multiple pores are visible on the surface of the starch granule by microscopic technique.
  • Porous starch may be produced through an enzymatic hydrolysis of native starch granules with one or multiple amylolytic enzymes, such as alpha-amylase and amyloglucosidase, at a temperature inferior to the gelatinization temperature of the starch; the drying of the porous starch is performed through a flash dryer.
  • amylolytic enzymes such as alpha-amylase and amyloglucosidase
  • CN 101240082 A describes microporous starch granule, which is a starch granule having micropores on the surface, and a pore diameter of the micropores on the surface of the starch granule is 5 to 10 pm; and a method for producing the same.
  • the method of production is enzymatic hydrolysis through amylase, followed by spray drying.
  • Aim of the present invention is obtaining cosmetic composition based on starch microparticles with modified morphology through physical techniques, capable of acting as an alternative to the microplastics commonly used in cosmetic products.
  • the object of the present invention also concerns a method combining different physical manipulation techniques in order to obtain particles having controlled shape and dimension, different in form and dimensions from the particles of “native” starch, i.e. as provided in nature, obtained through physical isolation processes from vegetal tissues of the starting botanical species.
  • the starting starch is obtained from different crops like e.g. potato, maize, rice, wheat, tapioca, oat, ginger, mung bean, amaranth, white turmeric, Chinese taro, cowherb (Gypsophila vaccaria). Such list is representative and not exhaustive. Each of such starches is provided with different chemical-physical properties, and a characteristic swelling temperature, indicatively ranging 55-85°C.
  • modified starches obtainable according to the methods of the present invention are not intended to replace 1 : 1 the microplastics customarily used in cosmetic industry with an exact reproduction of the dimensions and shapes of said microparticles, but instead are intended to provide new white or coloured powders having texturizing properties and/or provided with other technically desirable properties in the final cosmetic products, as an alternative to microplastics.
  • modified starch microparticles obtainable according to the methods of the present invention range 0,1-100 pm, preferably 0,1-30 pm, even more preferably 0,1-20 pm.
  • figures 1A-1D show four microphotographs taken with SEM electronic microscope with different magnification (figure 1A 500x, figure IB 1500x, figure 1C 3000x, figure ID lO.OOOx) of starch microparticles obtained through a first method of enzymatic hydrolysis;
  • figures 2A-2D show four microphotographs taken with SEM electronic microscope with different magnification (figure 2A 500x, figure 2B 1500x, figure 2C 3000x, figure 2D lO.OOOx) of starch microparticles obtained through a second method of enzymatic hydrolysis;
  • figures 3A-3C show three microphotographs taken with SEM electronic microscope with different magnification (figure 3A 3000x, figure 3B 1500x, figure 3C 3000x) of starch microparticles obtained through a spray-drying method;
  • figures 4 show four microphotographs taken with SEM electronic microscope with different magnification (figure 1A 500x, figure IB 1500x, figure 1C 3000
  • compositions consisting of native starch microparticles, whose morphology is modified using the following physical methods.
  • the enzymatic hydrolysis of native starch according to the present invention comprises the following steps:
  • a first method for starch particle modification through enzymatic hydrolysis comprises the following steps:
  • Figures 1A-1D show porous maize starch particles obtained through the method of EXAMPLE 1.
  • Such particles can be suitably used in cosmetic compositions, e.g. in pressed powders for eyelid decoration (eyeshadow).
  • the obtained particles have enhanced flowability properties with respect to native starch. Moreover, their adhesion and homogeneity are also enhanced.
  • the average dimension of the so-obtained particles ranges 10 - 20 pm.
  • a second method for starch particle modification through enzymatic hydrolysis comprises the following steps:
  • Figures 2A-2D show porous maize starch particles obtained through the method of EXAMPLE 2.
  • Such particles can be suitably used in cosmetic compositions, e.g. in pressed powders for face decoration (face powder).
  • the obtained particles have enhanced flowability properties with respect to native starch. Moreover, their adhesion and homogeneity are also enhanced.
  • the average dimension of the so-obtained particles ranges 10 - 20 pm.
  • powders consisting of particles with lamellar morphology are crucial for countless applications: important examples thereof are talc, mica and kaolin, widely used.
  • important examples thereof are talc, mica and kaolin, widely used.
  • talc talc
  • mica talc
  • kaolin kaolin
  • the particles are characterized by flowability (the particles can disperse uniformly by gliding one over the other) and adhesion (the particles are provided with flat faces capable of optimizing the contact surface with skin).
  • Their accurate design can improve quality and consumer satisfaction, and obtaining such morphologies through renewable materials is a good opportunity.
  • trehalose or of other suitable mono- or di-saccharides, ensures a fine lamellar morphology by modulating the fragility of the aerogel.
  • Obtaining microscopic platelets or lamellae according to the present invention comprises the following steps:
  • step C grinding and micronizing the white block obtained in step C.
  • a colorant can be added, allowing to obtain coloured starch microparticles in lieu of white microparticles, which can be used to prepare eyeshadows, face powders, blush or rouge, etc.
  • the method for obtaining starch platelets or lamellae comprises the following steps:
  • the method according to the invention comprises the following steps:
  • the lyophilization temperature of about -80°C is of paramount importance. With a lyophilization temperature of -20 °C the same results cannot be obtained, in that the freezing speed of the gel water molecules determines in its turn the thickness of the walls of the cellular structure.
  • step B natural colorants or active ingredients are added to the solution, optionally containing trehalose, and such solution is added to the starch solution under stirring at room temperature for one hour.
  • Figures 5A-5F show six microphotographs taken with a microscope of coloured platelets or lamellae obtained through the abovedescribed method. As the microphotographs are black and white photographs, it is worth specifying that figure 5 A shows platelets or lamellae coloured with a blue colorant (blue spirulina), figure 5B shows platelets or lamellae coloured with a yellow colorant (safflower yellow), while figures 5C-5F show different nuances of red-rose (elderberry and beetroot extract), brown (walnut mordant dye).
  • Such particles can be suitably used in cosmetic compositions, e.g. powder foundation in lieu of the more classical white excipient (talc, mica).
  • the platelets or lamellae so obtained can stick to skin in a stronger way in comparison to native starch particles.
  • the average dimension of particles so obtained ranges 10 - 30 pm according to the intensity of grinding.
  • Microscopic spheres are an important component in a wide range of cosmetic products, among which creams, lotions, foundations, skincare products and others. Such spheres play crucial roles in the cosmetic field, among which the enhancement of sensorial aspects like spreadability, soft-focus effect and blendability. Obtaining spherical starch microparticles is an intriguing solution to the problem posed by microplastics pollution.
  • the attainment of this particular morphology is due to two specific steps: microprecipitation and drying through lyophilization.
  • the starch over its swelling temperature, is dripped into an alcoholic solution under stirring: the contact of the starch solution with a non-solvent leads to precipitation and microparticle generation.
  • the non-solvent is chosen among monofunctional alcohols, preferably C1-C4 alcohols or diols, both miscible with water.
  • the attainment of deflated or crumpled spheres according to the present invention comprises the following step:
  • step B dripping the starch solution in a hydrosoluble non-solvent, preferably monofunctional alcohols or diols, in a volume equal to the volume of water used in the solution of step A, under stirring at room temperature for less than one hour;
  • a hydrosoluble non-solvent preferably monofunctional alcohols or diols
  • step C grinding and/or sieving the white powder of step C.
  • deflated or crumpled spheres are shown in figures 6A, 6B.
  • starch particles are not perfectly spherical.
  • the treatment of native starch according to the above method modifies the shape of the native granules, giving them a more irregular shape, that in the present description was named “deflated or crumpled”, like a balloon that has been punctured and therefore is slightly deflated without exploding.
  • the method for the production of deflated or crumpled spheres comprises the following steps:
  • step C Grinding and/or sieving the white powder of step C.
  • Figures 6A-6B show two examples of deflated spheres obtained through the above-described method.
  • Such particles can be suitably used in cosmetic compositions, like e.g. powder lipsticks in lieu of the more classical polymeric texturizing agents.
  • the average dimension of the so-obtained particles ranges 10 - 30 pm according to the intensity of grinding.
  • a further morphology obtainable through the present invention is toroidal.
  • the toroid starch microparticles are solid particles characterized by a structure approximating a discoid shape with a tapering in the central portion (biconvex discoid).
  • Such particles conveniently combine the advantages of the lamellar morphology to those of the spheroidal morphology:
  • Toroid microparticles are an evolving field of research in materials science, with innovative potentials in different sectors, thanks to their versatility and unique properties.
  • such morphology is obtained through a physical manipulation (partial solubilization/re-precipitation) of starch.
  • a physical manipulation partial solubilization/re-precipitation
  • the non-solvent structures the starch particles, which undergo a remodelling so forming a toroid.
  • the non-solvents are monofunctional alcohols preferably C1-C4 or diols, both miscible with water. After filtration and freezing, the powder is treated in the freeze-dryer for drying.
  • the attainment of toroid microparticles according to the present invention comprises the following steps:
  • step D grinding and/or sieving the white powder obtained in step C.
  • the method for the production of toroid microparticles comprises the following steps: A. To 1 L of MilliQ H2O (obtained through ion-exchange resins), adding 55 g of starch so as to obtain a final concentration of 55 g/L. Under stirring, bringing the temperature to the swelling temperature of the specific starch (e.g. 66°C for maize starch) maintaining it for at least one hour;
  • Figures 7A-7D show the toroid particles obtained with the above-described method.
  • a toroid s a surface of revolution with a hole. The axis of revolution passes through the hole and so does not intersects the surface. https://en.wikipedia.org/wiki/Toroid.
  • the toroid particles are not perfect toroids, but exhibit various irregularities, see especially figure 7B and 7D. Such irregularity encompasses also the collapse of the hole radius to a point leading to biconcave-like particles (https://en.wikipedia.org/wiki/Biconcave_disc).
  • A dissolving the native starch in distilled water in a proportion ranging 1% - 30% in weight and heating the solution at a temperature ranging 70-100°C under stirring; optionally, adding trehalose or another mono- or di-saccharide to the solution;
  • Figures 3A-3C show some examples of morphologies obtainable by using the spray-drying process of the EXAMPLE 3 applied to starches.
  • the particles exhibit a peculiar rough morphology (deflated or crumpled spheres), different from any other native or modified starch on the market.
  • Such particles can be conveniently used in cosmetic compositions, like e.g. foundations in oil-in-water emulsions.
  • Such particles have the capability of modifying the touch of the formulation by enhancing the viscosity thereof, with respect to native starch.
  • the average dimension of the particles so obtained ranges 10 - 30 pm.
  • the product is obtained by inserting in a powder mixer the ingredients of the above table and mixing up to homogeneity (4 min at a speed of 2000 RPM).
  • the mixture is then dosed in a metallic pan and pressed in order to obtain said eyeshadow.
  • the product is obtained by inserting in a rotor-stator homogenizer the ingredients of the phase A up to homogeneity.
  • the ingredients of the phase B are added slowly under stirring.
  • the mixture is then homogenized at 10000 RPM to refine the emulsion and then brought to room temperature.
  • EXAMPLE 13 Lipstick The product is obtained by inserting in a mixer the ingredients of the above table and mixing up to the fusion temperature of the waxes and complete homogeneity of the mass, that is then casted in moulds, allowed to cool and extracted in the form of a lipstick “bullet”.
  • the cosmetic composition comprising starch particles with modified morphology according to the present invention can be used in the finished cosmetic products listed in EXAMPLES 9-13, but also in cosmetic products for skincare and haircare.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)

Abstract

Composition cosmétique comprenant des microparticules d'amidon de morphologie modifiée obtenue à partir d'amidon natif, caractérisée en ce que lesdites particules ont des dimensions allant de 1 à 100 μm et une forme choisie dans le groupe constitué par : les polyèdres irréguliers poreux, les plaquettes ou lamelles microscopiques, les sphères dégonflées ou froissées, les tores irréguliers ; et en ce que lesdites particules sont obtenues par des méthodes physiques de traitement, choisies dans le groupe constitué par : -hydrolyse enzymatique ; -microprécipitation en présence d'un non-solvant d'amidon ; -égouttement en présence d'un non-solvant d'amidon ; -lyophilisation ; - séchage par atomisation ; - broyage. Les compositions cosmétiques selon la présente invention, en plus d'avoir des propriétés de texturation, peuvent avantageusement remplacer les microplastiques contenus dans des produits cosmétiques finis.
PCT/IB2025/052610 2024-03-20 2025-03-12 Composition cosmétique contenant des particules d'amidon à morphologie contrôlée et procédés d'obtention desdites particules Pending WO2025196581A1 (fr)

Applications Claiming Priority (2)

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IT202400006196 2024-03-20
IT102024000006196 2024-03-20

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101240082A (zh) * 2008-02-22 2008-08-13 浙江工业大学 一种微孔淀粉粒及其生产方法
WO2021144245A1 (fr) * 2020-01-14 2021-07-22 Roquette Freres Amidon natif et poreux en tant que pigment blanc dans la pâte dentifrice
WO2021175775A1 (fr) * 2020-03-05 2021-09-10 Intercos S.P.A. Composition cosmétique à amidon optimisé et applications cosmétiques de celle-ci
US20220265525A1 (en) * 2019-08-20 2022-08-25 Jgc Catalysts And Chemicals Ltd. Particles containing starch, method for producing same, and cosmetic preparation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101240082A (zh) * 2008-02-22 2008-08-13 浙江工业大学 一种微孔淀粉粒及其生产方法
US20220265525A1 (en) * 2019-08-20 2022-08-25 Jgc Catalysts And Chemicals Ltd. Particles containing starch, method for producing same, and cosmetic preparation
WO2021144245A1 (fr) * 2020-01-14 2021-07-22 Roquette Freres Amidon natif et poreux en tant que pigment blanc dans la pâte dentifrice
WO2021175775A1 (fr) * 2020-03-05 2021-09-10 Intercos S.P.A. Composition cosmétique à amidon optimisé et applications cosmétiques de celle-ci

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KOZLOWSKA JUSTYNA ET AL: "Microparticles based on natural and synthetic polymers for cosmetic applications Kozlowska", vol. 129, 1 May 2019 (2019-05-01), pages 5 - 2019, XP009525008, ISSN: 0141-8130, Retrieved from the Internet <URL:https://www.sciencedirect.com/science/article/pii/S0141813019305914> [retrieved on 20240926], DOI: 10.1016/J.IJBIOMAC.2019.02.091 *
WU WENQI ET AL: "Effects of Extrusion Technology Combined with Enzymatic Hydrolysis on the Structural and Physicochemical Properties of Porous Corn Starch", FOOD AND BIOPROCESS TECHNOLOGY ; AN INTERNATIONAL JOURNAL, SPRINGER-VERLAG, NEW YORK, vol. 13, no. 3, 9 January 2020 (2020-01-09), pages 442 - 451, XP037053215, ISSN: 1935-5130, [retrieved on 20200109], DOI: 10.1007/S11947-020-02404-1 *

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