[go: up one dir, main page]

WO2025165676A1 - Dispositif de sécurité de médicament dangereux - Google Patents

Dispositif de sécurité de médicament dangereux

Info

Publication number
WO2025165676A1
WO2025165676A1 PCT/US2025/013115 US2025013115W WO2025165676A1 WO 2025165676 A1 WO2025165676 A1 WO 2025165676A1 US 2025013115 W US2025013115 W US 2025013115W WO 2025165676 A1 WO2025165676 A1 WO 2025165676A1
Authority
WO
WIPO (PCT)
Prior art keywords
connector
adapter
engagement member
longitudinal axis
housing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/US2025/013115
Other languages
English (en)
Inventor
Linda KUNARDI
Kiat Jin Cheng
Say Kiong Toh
Yun Hui WONG
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Becton Dickinson and Co
Original Assignee
Becton Dickinson and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Becton Dickinson and Co filed Critical Becton Dickinson and Co
Publication of WO2025165676A1 publication Critical patent/WO2025165676A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M39/1011—Locking means for securing connection; Additional tamper safeties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2051—Connecting means having tap means, e.g. tap means activated by sliding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2055—Connecting means having gripping means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M2039/1027—Quick-acting type connectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M2039/1066—Tube connectors; Tube couplings having protection means, e.g. sliding sleeve to protect connector itself, shrouds to protect a needle present in the connector, protective housing, isolating sheath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/10—Tube connectors; Tube couplings
    • A61M2039/1072—Tube connectors; Tube couplings with a septum present in the connector

Definitions

  • the present disclosure relates generally to devices and methods of use thereof for the closed transfer of fluids. More particularly, the present disclosure relates to a releasably engageable components for secure fluid transfer.
  • the present disclosure provides a connector, including a first end, a second end opposite the first end, and a longitudinal axis extending from the first end to the second end; a piercing member proximate the first end, the piercing member including at least one opening therein; a membrane proximate the second end; a lumen extending from the at least one opening of the piercing member to the membrane; and at least one engagement member positioned between the first end and the second end, the at least one engagement member being movable in a direction transverse to the longitudinal axis, the at least one the engagement member including: a tab defining a depressible surface, and a shelf substantially transverse to the longitudinal axis.
  • the connector may include a flange longitudinally positioned between the piercing member and the second end, the flange having a width greater than a width of the piercing member.
  • the at least one the engagement member may be longitudinally positioned between the flange and the second end of the connector.
  • the at least one the engagement member may include a ramp longitudinally positioned between the shelf and the second end of the connector. The ramp may increase in width in a direction extending from the second end to the first end.
  • the at least one the engagement member may define a slot between the tab and the shelf.
  • the connector may include a plurality of engagement members radially spaced around the connector.
  • the at least one the engagement member may form a cantilever joint with the connector to enable movement in a direction transverse to the longitudinal axis.
  • the depressible surface of the tab may be substantially parallel to the longitudinal axis.
  • the shelf may be defined by an uppermost surface of the tab.
  • a system for transferring fluids including an adapter comprising: a housing defining a first end, a second end, and a longitudinal axis extending from the fist end to the second end; a cannula positioned within the housing; a seal arrangement movably positioned within the housing; a retention element proximate the second end of the housing; and a connector releasably attachable to the adapter, the connector comprising: a first end and a second end opposite the first end, the second end positionable within the housing of the adapter; a piercing member proximate the first end, the piercing member including at least one opening therein; a membrane proximate the second end; a lumen extending from the at least one opening of the piercing member to the membrane; and at least one engagement member positioned between the first end and the second end, the at least one engagement member being movable in a direction transverse to the longitudinal axis, wherein the at least one engagement
  • the retention element may define an abutment surface substantially transverse to the longitudinal axis.
  • the at least one engagement member may include a tab defining a depressible surface, the tab positioned exterior to the housing of the adapter when the adapter is coupled to the connector.
  • the housing of the adapter may define an opening at the second end configured to receive the second end of the connector therein, and the retention element may include a protruding rim circumscribing the opening at the second end of the adapter.
  • the adapter may include a spring to bias a position of the seal arrangement within the housing.
  • the connector may include a flange longitudinally positioned between the piercing member and the second end, the flange having a width greater than a width of the piercing member.
  • the at least one engagement member may be longitudinally positioned between the flange and the second end of the connector.
  • the at least one the engagement member may form a cantilever joint with the connector to enable movement in a direction transverse to the longitudinal axis.
  • the at least one the engagement member may include a ramp longitudinally positioned between the shelf and the second end of the connector.
  • the housing of the adapter may define an opening at the second end configured to receive the second end of the connector therein, and the retention element may include a raised rim above the opening defining at least one window between the raised rim and the housing, and the shelf of the at least one engagement member may be positionable in the at least one window.
  • FIG. 1 is a perspective view of an example of a connector in accordance with the principles of the present disclosure
  • FIG. 2 is a front view of the connector of FIG. 1;
  • FIG. 3 is a side view of a portion of the connector of FIG. 1;
  • FIG. 4 is a perspective view of an example of a syringe adapter in accordance with the principles of the present disclosure
  • FIG. 5 is a side view of the connector of FIG. 1 assembled with the syringe adapter of FIG. 4;
  • FIG. 6 is a cross-sectional view of the assembly of FIG. 5;
  • FIG. 7 is a closer cross-sectional view of a portion of the assembly of FIGS. 5-6;
  • FIG. 8 is a front view of another example of a connector in accordance with the principles of the present disclosure.
  • FIG. 9 is a perspective view of another example of a syringe adapter in accordance with the principles of the present disclosure.
  • FIG. 10 is a side view of the connector of FIG. 8 assembled with the syringe adapter of FIG. 9; and [0021] FIG. 11 is a cross-sectional view of a portion of the assembly of FIG. 10.
  • “at least one of’ is synonymous with “one or more of.”
  • the phrase “at least one of A, B, or C” means any one of A, B, or C, or any combination of any two or more of A, B, or C.
  • “at least one of A, B, and C” includes A alone; or B alone; or C alone; or A and B; or A and C; or B and C; or all of A, B, and C.
  • the terms “parallel” or “substantially parallel” mean a relative angle as between two objects (if extended to theoretical intersection), such as elongated objects and including reference lines, that is from 0° to 5°, or from 0° to 3°, or from 0° to 2°, or from 0° to 1°, or from 0° to 0.5°, or from 0° to 0.25°, or from 0° to 0.1°, inclusive of the recited values.
  • the terms “perpendicular”, “transverse”, “substantially perpendicular,” or “substantially transverse” mean a relative angle as between two objects at their real or theoretical intersection is from 85° to 90°, or from 87° to 90°, or from 88° to 90°, or from 89° to 90°, or from 89.5° to 90°, or from 89.75° to 90°, or from 89.9° to 90°, inclusive of the recited values.
  • the present disclosure provides systems and methods of use thereof for the secure, closed transfer of potentially hazardous compounds.
  • a system generally including a connector 10 and a syringe adapter 12 operable to provide secure transfer of fluid is shown.
  • an example of the connector 10 is shown and generally includes or defines a first end 14, a second end 16 opposite the first end 14, and a longitudinal axis 18 extending along the length of the connector 10 between the first and second ends.
  • the connector 10 includes or defines a piercing member 20 substantially parallel to the longitudinal axis 18 and extending towards or otherwise defining the first end 14 of the connector 10.
  • the piercing member 20 includes an angled, pointed, or sharp surface configured to pierce a membrane, seal, or other barrier of a fluid container or other component of a fluid delivery or storage system.
  • the piercing member 20 includes one or more openings 22 in fluid communication with a lumen 24 extending along an interior of the connector 10 from the first end 14 to the second end 16.
  • the openings 22 may be defined or included in a sidewall or surface of the piercing member 20 to avoid blockage or coring when the piercing member 20 is inserted through a membrane or barrier.
  • the connector 10 may include a membrane 26 at or adjacent to the second end 16 of the connector.
  • the membrane 26 seals the lumen 24 at or near the second end 16 of the connector 10 until pierced for secure transfer of fluids as described further herein.
  • the membrane 26 may include one or segments of fluid impermeable material, layers, coatings or otherwise to prevent or substantially reduce fluid flow through the lumen at the second end 16.
  • the connector 10 may include or define a flange 28 extending radially substantially perpendicular or transvers to the longitudinal axis 18. The flange 28 may be positioned at or adjacent to a base 30 of the piercing member 20 opposite the first end 14 where the angled, pointed, or sharp surface of the piercing member 20 resides.
  • the flange 28 may define a dimeter or width greater than a diameter or width of the piercing member 20 such that the flange 28 is operable or configured to seal a connection between the connector 10 and a fluid container, such as an IV bag or the like, when the piercing member 20 is inserted therein.
  • the connector 10 includes a locking mechanism operable and configured to releasably engage or couple the connector 10 to the adapter 12.
  • the locking mechanism includes one or more engagement members 32 positioned on or extending from a portion of the connector 10.
  • the engagement members 32 may couple to or extend from a portion of the connector at a base or joint 34 located between the flange 28 and the second end 16 in the direction of the longitudinal axis 18.
  • the base or joint 34 may include a cutout, curvature, living hinge, or other structure enabling at least a portion of the engagement members 32 to move laterally or radially in a direction substantially transverse or perpendicular to the longitudinal axis 18. As shown in FIGS.
  • a slot is defined between the engagement members 32 and the connector 10, which allows for lateral or radial movement of the engagement members 32.
  • a length and width of the slot between the engagement members 32 and the connector 10 can be varied to change the force and amount of deflection of the engagement members 32.
  • the one or more engagement members 32 may be biased to retain or return to a particular radial or lateral position upon the application and removal of force.
  • the one or more engagement members 32 may include or constitute a cantilever arm that is depressible and movable inwardly in a radial or lateral direction, but returns to an initial outward position when the inward force is removed.
  • Each of the one or more engagement members 32 may include or define a depressible tab 36 on an upper portion thereof operable and configured to actuate movement of the engagement members 32 in a lateral or radial direction.
  • the tab 36 may be longitudinally positioned between the flange 28 and the base or joint 34.
  • the tab 36 may include or define a surface 36a substantially parallel to the longitudinal axis 18 facilitating manual pressing and resultant movement of the tab 36, and an underside surface 36b substantially perpendicular or transverse to the axis 18.
  • the engagement members 32 and/or the tab 36 may be configured such that at least a portion of the tab 36 extends beyond a perimeter of the flange 28 for ease of access and operation, as described further herein.
  • the one or more engagement members 32 may each define a shelf 38 that is substantially perpendicular or transverse to the longitudinal axis 18.
  • the shelf 38 may be longitudinally positioned on or defined by each engagement member 38 between the underside surface 36b of the tab 36 and the base or joint 34.
  • Each of the one or more engagement members 32 may further define or include a slot 40 formed between the underside surface 36b of the tab 36 and the shelf 38, where the slot 40 receives and is engageable with a portion of the adapter 12 as described further herein.
  • the one or more engagement members 32 may each define a ramp or angled surface 42 protruding therefrom adjacent to the shelf 38.
  • the ramp 42 may be longitudinally positioned between the shelf 38 and the base or joint 34.
  • the ramp 42 may be angled with respect to both the longitudinal axis 18 and the shelf 38 and be operable or configured to move the one or more engagement members 32 inward radially or laterally when a force is exerted thereon.
  • the ramp 42 may increase in width in a direction extending from the second end to the first end.
  • the ramp 42 may form a camming arrangement such that an axial force applied to the engagement members 32 results in lateral or radial movement of the engagement members 32.
  • the connector 10 may include a plurality of engagement members 32 radially spaced or positioned about the connector. In the illustrated example, there are two engagement members positioned radially opposite each other (e.g., 180 degrees apart) around the circumference or perimeter of the connector 10. The quantity and placement of the engagement members may be modified to suit a particular application or use.
  • the size, shape, and configuration of the various features of the engagement members 32 may be modified to provide a desired degree of movement, displacement, or force exertion during assembly, disassembly, and/or use of the components and features described herein.
  • the connector 10 may be constructed or molded as a unitary component, or alternatively may be assemble from distinct parts to provide the features described herein.
  • the connector 10 may be constructed from one or more sterilizable and/or biocompatible polymers, metals, and/or alloys or mixtures thereof.
  • the syringe adapter 12 is configured to receive at least a portion of the connector 10 therein, and is further configured to connect to a syringe (not shown) or other medical device or fluid container.
  • the medical device can be, for example, a patient line, vial adapter, fluid container, or infusion adapter.
  • the container can be a medical vial, syringe barrel, IV bag, or similar container for holding a fluid to be administered to a patient.
  • the syringe adapter 12 can be used to facilitate the closed transfer of fluids between the syringe, through the connector 10, and into a medical device or fluid container.
  • the syringe adapter 12 is similar to and operates in a similar manner as the syringe adapter shown and described in United States Patent No. 10,744,315, which is hereby incorporated by reference in its entirety.
  • the adapter 12 includes a housing 44 having a first end 46, a second end 48, and an interior cavity 50.
  • the first end 46 of the housing 44 of the adapter 12 may include a syringe or device attachment feature 52, such as a female luer connector, that defines a passageway 54.
  • a female luer connector is shown for connection with a corresponding male luer connector of a syringe (not shown), other suitable connection arrangements may be utilized for connection to a syringe, container, or any other medical device.
  • a cannula 56 is secured to the housing 44 and defines a proximal end 58 adjacent to or otherwise in fluid communication with the passageway 54, and the cannula 56 defines or includes a distal end 60 within the cavity 50 of the housing 44 extending in the direction of the second end 48.
  • the adapter 12 further includes a seal arrangement 62 positioned within the housing 44 and configured to move within the interior cavity 50 in an axial direction along the longitudinal axis 18.
  • the seal arrangement 62 may include one or more collets or other structural framing components and/or one or more membranes, barriers, or other fluid impermeable features to prevent or substantially reduce fluid flow through the distal end 60 of the cannula 56 until the adapter 12 is coupled to the connector 10 and is otherwise prepared for fluid transport.
  • the adapter 12 may include a drive member 64 that biases the axially-movable seal arrangement 62 towards a first position adjacent to or in proximity to the second end 48 of the housing 44.
  • the drive member 64 may include a spring or other biasing means configured to provide the features described herein. Upon an application of an axial force, the biasing of the drive member 64 is overcome, and the seal arrangement 62 can be moved axially in a direction towards the first end 46 of the housing 44, such that the distal end 60 of the cannula 56 pierces or otherwise passes through the seal arrangement 62, as described further herein.
  • the adapter 12 defines or includes an opening 66 at the second end 48 that is sized and shaped to receive at least a portion of the connector 10 therethrough.
  • the second end 16 of the connector 10 is positionable through the opening 66 in the second end 48 of the housing 44 such that at least a portion of the connector 10 is positioned within the interior cavity 50 of the housing 44.
  • the connector 10 may be positioned within the housing 44 such that the membrane 26 of the connector 10 abuts or is otherwise adjacent to the seal arrangement 62 of the adapter 12.
  • the adapter 12 may include or define one or more retention elements 68 adjacent to or in proximity to the opening 66 at the second end 48 of the housing 44.
  • the one or more retention elements 68 may be operable or otherwise configured to engage the locking mechanism of the connector 10 for attachment and detachment of the connector to the adapter 12.
  • the one or more retention elements 68 may include, for example, a protruding rim circumscribing the opening 66 of the housing 44 and having a smaller diameter than the opening 66 that is engageable within the slot 40 of the engagement members 32 of the connector.
  • the one or more retention elements 68 may include, for example, one or more discrete protrusions extending inwardly around the opening 66 that are engageable within the slot 40 of the engagement members 32 of the connector.
  • the retention element 68 includes or defines an abutment surface 68a substantially perpendicular to the longitudinal axis 18 configured to abut the shelf 38 of the one or more engagement members 32 of the connector 10. The adjacent positioning of the retention element 68 and the shelf 38 prevents unintended axial separation between the connector 10 and the adapter 12, as described herein.
  • the connector 10 is engaged with the adapter to provide a secure fluid flow path therethrough for the delivery of drugs or other medicaments.
  • the second end 16 of the connector 10 may be passed through the opening 66 of the second end 48 of the adapter 12.
  • the one or more retention elements 68 may come into contact with at least a portion of the one or more engagement members 32 of the connector 10 such that the one or more engagement members 32 are moved inward in a radial or lateral direction.
  • the inward deflection of the engagement members 32 may result from the retention elements 68 or other portion of the housing 44 contacting and exerting a radial/lateral force on the ramp 42 of the engagement members 32.
  • the assembled adapter 12 and connector 10 provides a fluid flow path through the passageway 54 in the first end 46 of the adapter 12, through the cannula 56, into the lumen 24 extending through the piercing member 20 of the connector, and out of the openings 22 at the first end 14 of the connector 10.
  • the piercing member 20 may be inserted into a container, IV line or bag, or other component of a fluid transfer system for transfer of fluids.
  • the tabs 36 remain outside of the cavity 50 of the adapter 12 and/or are otherwise accessible for manual actuation.
  • the connector 10 remains axially secured to the connector 12 until a radial/lateral force is applied to the tabs 36 to disengage the shelf 38 from the abutment surface 68, thereby allowing axial displacement between the connector 10 and the adapter 12. Requiring a radial disconnect force reduces the likelihood that the connector 10 will be inadvertently disconnected from the adapter 12 solely by an axial force, which could typically be exerted during insertion, positioning, and/or or removal of the piercing member from an IV system or container.
  • the one or more engagement members 32 of the connector 10 may define the shelf 38 on an uppermost surface of the tab 36, and the depressible surface 36a of the tab 36 that remains outside the cavity 50 of the housing 44 may be angled with respect to the longitudinal axis 18.
  • the retention element 68 of the adapter 12 may include a raised rim or annular rib above the opening 66 at the second end 48 of the housing 44 of the adapter 12.
  • the retention element 68 may include or define one or more windows 70 therein or with respect to other surfaces of the housing 44.
  • the shelf 38 When the connector 10 is inserted into the interior cavity 50 of the housing 44, the shelf 38 is positioned at least partially within the one or more windows 70 to contact the abutment surface 68a formed on an upper portion of the one or more windows 70.
  • the engagement or contact between the shelf 38 and abutment surface 68a prevents axial displacement between the connector 10 and the adapter 12 unless the engagement members 32 are laterally or radially displaced, as described above.

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La divulgation concerne un raccord comprenant : une première extrémité, une seconde extrémité opposée à la première extrémité, et un axe longitudinal s'étendant de la première extrémité à la seconde extrémité ; un élément de perçage à proximité de la première extrémité, l'élément de perçage présentant au moins une ouverture ; une membrane à proximité de la seconde extrémité ; une lumière s'étendant de ladite au moins une ouverture de l'élément de perçage à la membrane ; et au moins un élément de mise en prise placé entre les première et seconde extrémités, ledit au moins un élément de mise en prise étant mobile dans une direction transversale à l'axe longitudinal, et comprenant une languette définissant une surface pouvant être enfoncée, et une tablette sensiblement transversale à l'axe longitudinal.
PCT/US2025/013115 2024-02-01 2025-01-27 Dispositif de sécurité de médicament dangereux Pending WO2025165676A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202463548562P 2024-02-01 2024-02-01
US63/548,562 2024-02-01

Publications (1)

Publication Number Publication Date
WO2025165676A1 true WO2025165676A1 (fr) 2025-08-07

Family

ID=96591355

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2025/013115 Pending WO2025165676A1 (fr) 2024-02-01 2025-01-27 Dispositif de sécurité de médicament dangereux

Country Status (1)

Country Link
WO (1) WO2025165676A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545152A (en) * 1994-10-28 1996-08-13 Minimed Inc. Quick-connect coupling for a medication infusion system
US20150123398A1 (en) * 2013-11-06 2015-05-07 Becton Dickinson and Company Limited System for Closed Transfer of Fluids With a Locking Member
US20180200147A1 (en) * 2017-01-17 2018-07-19 Becton Dickinson and Company Limited Syringe Adapter for Closed Transfer of Fluids
WO2023070096A1 (fr) * 2021-10-21 2023-04-27 Aktivax, Inc. Raccord réduisant le volume mort

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5545152A (en) * 1994-10-28 1996-08-13 Minimed Inc. Quick-connect coupling for a medication infusion system
US20150123398A1 (en) * 2013-11-06 2015-05-07 Becton Dickinson and Company Limited System for Closed Transfer of Fluids With a Locking Member
US20180200147A1 (en) * 2017-01-17 2018-07-19 Becton Dickinson and Company Limited Syringe Adapter for Closed Transfer of Fluids
WO2023070096A1 (fr) * 2021-10-21 2023-04-27 Aktivax, Inc. Raccord réduisant le volume mort

Similar Documents

Publication Publication Date Title
US12427297B2 (en) Connector for system for closed transfer of fluids
EP3570807B1 (fr) Adaptateur pour seringue pour transfert de fluides en circuit fermé
EP3570931B1 (fr) Adaptateur de seringue avec mécanisme de verrouillage
US12072049B2 (en) Connector coupling assembly
US20240424279A1 (en) Connector coupling assembly
WO2025165676A1 (fr) Dispositif de sécurité de médicament dangereux
US20250180147A1 (en) Non-disconnecting rotatable connector assembly

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 25748852

Country of ref document: EP

Kind code of ref document: A1