[go: up one dir, main page]

WO2025160398A3 - Appareils, systèmes et procédés de commande de distribution d'énergie à un tissu comprenant des exemples de forme d'onde - Google Patents

Appareils, systèmes et procédés de commande de distribution d'énergie à un tissu comprenant des exemples de forme d'onde

Info

Publication number
WO2025160398A3
WO2025160398A3 PCT/US2025/012956 US2025012956W WO2025160398A3 WO 2025160398 A3 WO2025160398 A3 WO 2025160398A3 US 2025012956 W US2025012956 W US 2025012956W WO 2025160398 A3 WO2025160398 A3 WO 2025160398A3
Authority
WO
WIPO (PCT)
Prior art keywords
electrodes
segments
examples
control
energy delivery
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/US2025/012956
Other languages
English (en)
Other versions
WO2025160398A2 (fr
Inventor
Kenneth AYCOCK
Timothy O'brien
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Intuitive Surgical Operations Inc
Original Assignee
Intuitive Surgical Operations Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Intuitive Surgical Operations Inc filed Critical Intuitive Surgical Operations Inc
Publication of WO2025160398A2 publication Critical patent/WO2025160398A2/fr
Publication of WO2025160398A3 publication Critical patent/WO2025160398A3/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B18/1492Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053Mechanical features of the instrument of device
    • A61B2018/00214Expandable means emitting energy, e.g. by elements carried thereon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00482Digestive system
    • A61B2018/00494Stomach, intestines or bowel
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577Ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/0075Phase
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/00761Duration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/00767Voltage
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B2018/124Generators therefor switching the output to different electrodes, e.g. sequentially
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B2018/1246Generators therefor characterised by the output polarity
    • A61B2018/1253Generators therefor characterised by the output polarity monopolar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B2018/1246Generators therefor characterised by the output polarity
    • A61B2018/126Generators therefor characterised by the output polarity bipolar
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/1206Generators therefor
    • A61B2018/1266Generators therefor with DC current output
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • A61B2018/1407Loop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1405Electrodes having a specific shape
    • A61B2018/142Electrodes having a specific shape at least partly surrounding the target, e.g. concave, curved or in the form of a cave
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14Probes or electrodes therefor
    • A61B2018/1467Probes or electrodes therefor using more than two electrodes on a single probe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/20Applying electric currents by contact electrodes continuous direct currents
    • A61N1/30Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
    • A61N1/303Constructional details
    • A61N1/306Arrangements where at least part of the apparatus is introduced into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/327Applying electric currents by contact electrodes alternating or intermittent currents for enhancing the absorption properties of tissue, e.g. by electroporation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Plasma & Fusion (AREA)
  • Medical Informatics (AREA)
  • Otolaryngology (AREA)
  • Physics & Mathematics (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Electrotherapy Devices (AREA)

Abstract

La présente invention concerne, à titre d'exemple, des techniques d'excitation pour une ablation. Dans certains exemples, un dispositif d'ablation auto-dimensionnable peut comprendre un circuit flexible comprenant de multiples segments d'électrodes. Des circuits générateurs peuvent exciter individuellement des électrodes des multiples segments. Le circuit générateur peut utiliser des champs électriques pulsés pour commander l'activation de segments sélectionnés d'électrodes des multiples segments d'électrodes pour commander une quantité d'énergie appliquée à la région de traitement au-dessous d'un seuil d'énergie pour une stimulation musculaire. Dans certains exemples, le circuit générateur peut fournir des impulsions à des segments d'électrodes d'une manière bipolaire ou monopolaire. En sélectionnant des zones d'ablation par activation sélective de segments d'électrodes dans une séquence, et une quantité et des polarités de tensions ou de courants destinés à exciter des électrodes, une stimulation musculaire peut être réduite. Des exemples de formes d'onde destinées à être utilisées dans la distribution d'énergie sont décrits.
PCT/US2025/012956 2024-01-24 2025-01-24 Appareils, systèmes et procédés de commande de distribution d'énergie à un tissu comprenant des exemples de forme d'onde Pending WO2025160398A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US202463624613P 2024-01-24 2024-01-24
US63/624,613 2024-01-24
US202463719029P 2024-11-11 2024-11-11
US63/719,029 2024-11-11

Publications (2)

Publication Number Publication Date
WO2025160398A2 WO2025160398A2 (fr) 2025-07-31
WO2025160398A3 true WO2025160398A3 (fr) 2025-09-04

Family

ID=94733132

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2025/012956 Pending WO2025160398A2 (fr) 2024-01-24 2025-01-24 Appareils, systèmes et procédés de commande de distribution d'énergie à un tissu comprenant des exemples de forme d'onde

Country Status (1)

Country Link
WO (1) WO2025160398A2 (fr)

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013052590A1 (fr) * 2011-10-04 2013-04-11 Vessix Vascular, Inc. Appareil et procédé de traitement d'une resténose sur endoprothèse
EP3173043A1 (fr) * 2008-11-11 2017-05-31 Shifamed Holdings, LLC Ensemble d'électrode à profil bas
EP3248561A1 (fr) * 2016-05-23 2017-11-29 Covidien LP Générateur électrochirurgical, système et procédé d'essai non-chirurgical d'électroporation irréversible thermorésistant
US20180303543A1 (en) * 2017-04-24 2018-10-25 Medtronic Cryocath Lp Enhanced electroporation of cardiac tissue
WO2020051241A1 (fr) * 2018-09-04 2020-03-12 Inter Science Gmbh Procédés, systèmes et appareils pour ablation tissulaire utilisant une impulsion de décroissance exponentielle modulée
WO2021081131A1 (fr) * 2019-10-21 2021-04-29 DyaMX, Inc. Dispositifs, systèmes et méthodes de traitement par champ électrique pulsé du duodénum
WO2021113463A1 (fr) * 2019-12-03 2021-06-10 St. Jude Medical, Cardiology Division, Inc. Système et procédé d'électroporation
WO2023049954A1 (fr) * 2021-10-01 2023-04-06 Microfield Global Pty Ltd Procédé, systèmes, appareils et dispositifs de caractérisation et d'ablation de tissus cardiaques par électroporation réversible et électrolyse
WO2023205469A1 (fr) * 2022-04-22 2023-10-26 Intuitive Surgical Operations, Inc. Perméabilisation et électrolyse pour ablation avec rétention de matrice extracellulaire

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3173043A1 (fr) * 2008-11-11 2017-05-31 Shifamed Holdings, LLC Ensemble d'électrode à profil bas
WO2013052590A1 (fr) * 2011-10-04 2013-04-11 Vessix Vascular, Inc. Appareil et procédé de traitement d'une resténose sur endoprothèse
EP3248561A1 (fr) * 2016-05-23 2017-11-29 Covidien LP Générateur électrochirurgical, système et procédé d'essai non-chirurgical d'électroporation irréversible thermorésistant
US20180303543A1 (en) * 2017-04-24 2018-10-25 Medtronic Cryocath Lp Enhanced electroporation of cardiac tissue
WO2020051241A1 (fr) * 2018-09-04 2020-03-12 Inter Science Gmbh Procédés, systèmes et appareils pour ablation tissulaire utilisant une impulsion de décroissance exponentielle modulée
WO2021081131A1 (fr) * 2019-10-21 2021-04-29 DyaMX, Inc. Dispositifs, systèmes et méthodes de traitement par champ électrique pulsé du duodénum
WO2021113463A1 (fr) * 2019-12-03 2021-06-10 St. Jude Medical, Cardiology Division, Inc. Système et procédé d'électroporation
WO2023049954A1 (fr) * 2021-10-01 2023-04-06 Microfield Global Pty Ltd Procédé, systèmes, appareils et dispositifs de caractérisation et d'ablation de tissus cardiaques par électroporation réversible et électrolyse
WO2023205469A1 (fr) * 2022-04-22 2023-10-26 Intuitive Surgical Operations, Inc. Perméabilisation et électrolyse pour ablation avec rétention de matrice extracellulaire

Also Published As

Publication number Publication date
WO2025160398A2 (fr) 2025-07-31

Similar Documents

Publication Publication Date Title
CN113573655B (zh) 用于选择性细胞消融的空间复用波形
US11464968B2 (en) Stacked potential electroporation
EP4606419A3 (fr) Systèmes, dispositifs et procédés d'administration d'énergie d'ablation par champ électrique pulsé à un tissu endocardiaque
US20240374301A1 (en) Time multiplexed waveform for selective cell ablation
EP4461344A3 (fr) Systèmes, appareils et procédés de filtrage de bruit haute tension induit par ablation par champ électrique pulsé
IL307756A (en) Devices, systems and methods for the treatment of pulsating electric field in tissues
GB2453294A (en) Method of powering implanted devices by direct transfer of electrical energy
Clayton et al. Brain stimulation: Neuromodulation as a potential treatment for motor recovery following traumatic brain injury
EP3984484A1 (fr) Utilisation de configuration unipolaire pour électroporation irréversible (ire)
JP7572159B2 (ja) 美容器
GB2590287A (en) System and method for adjusting available power per probe during an ablation procedure
WO2021181231A3 (fr) Équipement d'ablation pour administrer une énergie non thermique pour traiter des régions cibles de tissu dans des organes et son procédé de commande
AU2020369800B2 (en) Iontophoresis administration device
WO2025160398A3 (fr) Appareils, systèmes et procédés de commande de distribution d'énergie à un tissu comprenant des exemples de forme d'onde
WO2022072385A3 (fr) Forme d'onde de traitement préalable d'électroporation irréversible
KR20220093918A (ko) 전기천공과 전기분해를 이용한 세포사멸 촉진 장치
WO2004045706A2 (fr) Methode et appareil electrochimiques de musculation
US20210361962A1 (en) Devices and methods for contactless delivering pulsed electric fields to skin tissue
AU2019396834B2 (en) Method and system for controlling molecular electrotransfer
RU181726U1 (ru) Аппарат транскраниальной электростимуляции эндорфинных механизмов мозга
CN117959581A (zh) 美容仪
US10086198B1 (en) Electrostimulation principle, method and device for impedance change theoretically enhancing calcium-calmodulin binding
EP4496624A1 (fr) Régénération nerveuse dirigée par champ électrique
RU2021123921A (ru) Подача биполярной абляционной энергии между группами замыкаемых накоротко электродов
HK40056948A (en) Beautifier

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 25707212

Country of ref document: EP

Kind code of ref document: A2