WO2025158322A1

WO2025158322A1 - Stable synergistic pesticidal composition comprising fungicide and insecticides

Info

Publication number: WO2025158322A1
Application number: PCT/IB2025/050717
Authority: WO
Inventors: Sunita Malhotra
Original assignee: Individual
Current assignee: Individual
Priority date: 2024-01-23
Filing date: 2025-01-23
Publication date: 2025-07-31
Anticipated expiration: 2026-07-23

Abstract

The present invention relates to a stable synergistic pesticidal composition comprising fungicide and insecticides.

Description

STABLE SYNERGISTIC PESTICIDAL COMPOSITION COMPRISING FUNGICIDE AND INSECTICIDES

FIELD OF THE INVENTION

The present invention relates to a stable synergistic pesticidal composition comprising fungicide and insecticides. In particular, the present invention relates to a stable synergistic pesticidal composition comprising A) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives; B) Abamectin or its agrochemically acceptable salts, esters and derivatives and C) a compound of Formula I, chemically known as methyl (2E)-2- methoxyimino-2- [2- [ [(E)- 1 - [3 - (trifluoromethyl)phenyl]ethylideneamino]oxymethyl]phenyl]acetate or its agrochemically acceptable salts, esters and derivatives. The present invention also relates to a process for preparation of such stable synergistic pesticidal composition for synergistic and efficacious control of wide variety of insect pests and fungal pests.

BACKGROUND OF THE INVENTION

Pesticides are compounds or mixtures of substances that are mostly employed in public health programmes or agriculture in order to protect plants from pests, weeds or diseases. Typical pesticides include insecticides, fungicides, herbicides, rodenticides, and plant growth regulators.

Combination of different pesticides with diverse mode of action for broad spectrum insect control is known in the art. However, repeated use of insecticides often lead to resistance development. Insecticide resistance is a heritable change in pest populations that are susceptible to a particular insecticide, or group of insecticides. In practice, insecticide resistant insects are insects that cannot be repeatedly and properly controlled by the registered rate of an insecticide. Pest populations may not be affected by multiple applications of insecticide at normal rate if the insecticide resistance level is high.

Combination of insecticides and fungicides are used to broaden the spectrum of control of insects and fungal pests, reduce dosages, thereby reducing their environmental impact, and reducing the likelihood of development of resistance. The combination of insecticides and fungicides improves the control of insects and fungal disease. Treating crops with combination of insecticides and fungicides helps reduce the damage caused by soil pests. Another advantage of treating crops or certain plant propagation materials is that higher yields can be obtained by improving germination rates, increasing the plant stand count, improved plant health. Fungal infection and insect infestation can happen at the same time in many commercially valuable crops, including rice, peppers, grapes, and other agricultural products.

There are various combinations of insecticides along with other insecticides or fungicides known in the art for the control of various pests. For instance, CN107593723A relates to a binary composition comprising Fluxametamide, as component A along with that one other insecticide or bactericide as component B.

Reference can also be made from CN110199999A which discloses a pesticidal binary composition containing Fluxametamide and Tolfenpyrad.

Further, patent application number IN201731033800A relates to combinations comprising a diamide insecticide in combination with fungicidally active compounds and plant health promoting agents for controlling unwanted animal pests, such as insects, acaricides and/or nematodes, and unwanted phytopathogenic fungi.

Pesticide active compounds are commonly used in the form of a diluted aqueous composition because they can achieve good interactions with the target organisms, such as plants, fungi and insects. However, most active pesticide compounds used as pesticides are only sparingly or even insoluble in water.

It has been noted that when chemical compounds such as fungicides, and insecticides are used more frequently, crops are growing accustomed to and resistant to the usage of compositions containing single active ingredients. Thus, there is a need for improvement of these combinations. Single active combinations used over a long period of time have resulted in resistance. With the onset of resistance to certain pests, there is a need in the art for a combination of actives that decreases chances of resistance and improves the spectrum of disease and pest control.

The combating of harmful phytopathogenic fungi is in many regions not the only problems the farmers have to face, as harmful insects can cause a great damage to crops and other plants. Thus, an efficient combination of fungicidal and insecticidal activity is desirable to overcome this problem. Accordingly, there exists a need for combining fungicides and insecticides belonging to different chemical classes and showing different mechanism of action and is useful various pests and plant diseases

Fluxametamide belong to the chemical group of isooxazoline and has the chemical name as N 4-[(RS)-5-(3,5-dichlorophenyl)-4,5-dihydro-5-(trifluoromethyl)isoxazol-3-yl]-N-[(EZ)- (methoxyimino)methyl]-o-toluamide or 4-[5-(3,5-dichlorophenyl)-4,5-dihydro-5- (trifluoromethyl)-3-isoxazolyl]-N-[(methoxyamino)methylene]-2-methylbenzamide.

Fluxametamide potently inhibit the specific binding of [³H]EBOB, [³H]4'-ethynyl-4-n- propylbicycloorthobenzoate to housefly-head membranes, suggesting that Fluxametamide affects insect y-aminobutyric acid (GABA)-gated chloride channels (GABACls). The chemical structure of Fluxametamide is provided below:

Abamectin is an insecticide belongs to the class of avermectin. It has a low aqueous solubility and is not volatile. It does not tend to be persistent in the environment. The action mechanism is to stimulate the release of a nerve transmission medium, namely r-aminobutyric acid, and interfere normal neurophysiological activities. Due to the osmosis, the influence of rainwater is small, and the fertilizer is safe to crops. Abamectin is adsorbed by soil in soil and cannot move and is decomposed by microorganisms, so that the abamectin has no accumulation effect in the environment and can be used as a component of comprehensive control. It mainly controls phytiphagus mites, leafminers, cockroachers, ants, pear psylla, nematodes including Meloidogyne spp It is used in wide variety of crops. It is used to kill insect pests in ornamental plants; fruit including citrus, pears, tomatoes, watermelon; Cotton; vegetable crops including eggplant, curcubits, beans. The structure of abamectin is shown as below:

Abamectin

Strobilurin fungicides are now more properly referred to as Qol fungicides. Qol fungicides are excellent as preventive fungicides, because they all effectively kill germinating spores. All Qol fungicides share a common biochemical mode of action: they all interfere with energy production in the fungal cell. They block electron transfer at the site of quinol oxidation (the Qo site) in the cytochrome bcl complex, thus preventing ATP formation. These fungicides control an unusually wide array of fungal diseases, including diseases caused by water molds, downy mildews, powdery mildews, leaf spotting and blighting fungi, fruit rotters, and rusts. They are used on a wide variety of crops, including cereals, field crops, fruits, tree nuts, vegetables, turfgrasses, and ornamentals.

Various strobilurin fungicides are known in the art. They are also categorised as systemic and translaminar strobilurin fungicides. Each of the strobilurin fungicide has different effective activity against fungal pests. Out of the known strobilurin fungicides, the Compound of Formula I i.e., methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3- (trifluoromethyl)phenyl]ethylideneamino]oxymethyl]phenyl]acetate, has shown to have better fungal pest control in comparison to other strobilurin fungicides.

The compound of Formula I is represented by the following chemical structure:

Compound of Formula I

The compound i.e. methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3-

(trifluoromethyl)phenyl]ethylideneamino]oxymethyl]phenyl]acetate shall be referred to as compound of Formula I in the entire specification and shall be meant to refer to this compound which has the IUPAC name and structure as mentioned herein above.

Therefore, the present invention aims to develop a stable synergistic pesticidal composition, which results in broader pesticidal spectrum of action. Thus, the present invention provides a composition for protecting plants, crops against fungal diseases and insect pests.

The present invention satisfies the existing needs, as well as others, and generally overcomes the deficiencies found in the prior art.

The present invention composition is synergistic, efficacious, environmentally friendly, simple to formulate, stable, safe to use and has longer shelf life.

OBJECTS AND ADVANTAGES OF THE INVENTION:

The principal object of the present invention is to provide a novel and effective synergistic pesticidal composition demonstrating high efficacy and to provide complete protection to crops, plants against insect-pests, mites, fungal diseases.

Another object of the present invention is to provide a novel and effective synergistic pesticidal composition as one shot application for controlling harmful pests in plants including brinjal, chilli, cabbage, okra, red-gram, tomato, rose grapes, rice wheat etc.

A further object of the present invention is to provide a novel and effective synergistic pesticidal composition which can be easily formulated.

A further object of the present invention is to provide a novel and effective synergistic pesticidal composition and a method of controlling pathogenic insect pests and fungus and for disease resistance management or to delay disease resistance development through engaging multiple modes of action.

A further object of the present invention is to provide a novel and effective synergistic pesticidal composition which provide excellent crop safety in terms of no phytotoxicity and no adverse effect on germination or growth of succeeding crops due to reduced amount of dosage.

A further object of the present invention is to provide a novel and effective synergistic pesticidal combination which has increased shelf life.

A further object of the present invention is to provide a novel process for preparing a pesticidal composition comprising synergistic combination of fungicide and insecticides. It is another objective of the present invention is to provide a novel and effective synergistic pesticidal composition that has both preventive and curative action in addition to phytotonic action; and is active against all life stages of major plant pathogens.

It is another objective of the present invention is to provide a novel and effective synergistic pesticidal composition that protects crop and the environmental damage.

It is another objective of the present invention to provide a novel and effective synergistic pesticidal composition that improves germination rate, increased plant stand count and plant health, which results in higher yields.

It is another objective of the present invention to provide a novel and effective synergistic pesticidal composition that improves quality and quantity of the targeted crops and plants.

It is another objective of the present invention to provide a novel and effective synergistic pesticidal composition that is ideal for pest resistance management and disease control.

It is another objective of the present invention is to provide a novel and effective synergistic pesticidal composition that is safe for environment, has broad spectrum bio-efficacy, and has no phyto toxicity.

It is another objective of the present invention to provide a novel and effective synergistic pesticidal composition that is stable over wide range temperatures and environmental changes.

It is another objective of the present invention to provide a novel and effective synergistic pesticidal composition with enhanced efficacy and penetration capacity.

Yet another objective of the present invention is to provide a novel and effective synergistic pesticidal composition that promotes plant health and improves crop yield.

Furthermore, the synergistic pesticidal composition has a phytotonic effect, which results in improved grain size and yield; and has improved stability and shelf life. Another object of the present invention is to provide a synergistic pesticidal composition comprising A) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives; B) Abamectin or its agrochemically acceptable salts, esters and derivatives and C) a compound of Formula I, chemically known as methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3- (trifluoromethyl)phenyl]ethylideneamino]oxymethyl]phenyl]acetate or its agrochemically acceptable salts, esters and derivatives.

Yet another object of the present invention is to provide a method of improving plant health and increasing crop yield by using synergistic pesticidal composition comprising A) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives; B) Abamectin or its agrochemically acceptable salts, esters and derivatives and C) a compound of Formula I, chemically known as methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3- (trifluoromethyl)phenyl]ethylideneamino]oxymethyl]phenyl]acetate or its agrochemically acceptable salts, esters and derivatives.

Some or all these and other objects of the invention can be achieved by way of the invention described hereinafter.

Advantages of the Present Invention:

1. The synergistic composition of the present invention resulted in significantly lower incidence of fruit borer, yellow rust, yellow mite and anthracnose disease in chilli crop as compared to the binary composition and untreated check.

2. The synergistic composition of the present invention is significantly superior from its individual product specifically manufactured by inventor or readily available in market in reducing the pest of chilli crop.

3. The synergistic composition of the present invention provides improved chilli yield as compared to the untreated control and binary and solo treatments applied in the chilli crop. Also found economical with higher Cost: Benefit Ratio.

4. The synergistic composition of the present invention shows no phytotoxicity effect on chilli crop.

5. The results of experiments indicate that the synergistic composition of the present invention is highly effective in controlling insect pest, diseases and increasing production of chilli at lower doses of the products in the combination, thus the invention will be cost effective and safer to the environment.

SUMMARY OF THE INVENTION

Accordingly, the main aspect of the present invention is to provide a synergistic pesticidal composition having high insect pests and fungus control efficacy.

Accordingly, the present invention relates to a synergistic pesticidal composition comprising: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives; b) Abamectin or its agrochemically acceptable salts, esters and derivatives and c) a compound of Formula I, chemically known as methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3- (trifluoromethyl)phenyl]ethylideneamino]oxymethyl]phenyl]acetate or its agrochemically acceptable salts, esters and derivatives, for synergistic and effective control of various pests, fungi, plant diseases.

In one embodiment of the present invention, the synergistic pesticidal composition comprises: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives; b) Abamectin or its agrochemically acceptable salts, esters and derivatives; and c) a compound of Formula I, i.e. methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3-

(trifluoromethy l)pheny 1] ethylideneamino] oxy methyl] phenyl] acetate or its agrochemically acceptable salts, esters and derivatives.

In yet another embodiment of the present invention, the synergistic pesticidal composition comprises: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives; b) Abamectin or its agrochemically acceptable salts, esters and derivatives; c) Compound of Formula I, i.e. methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3-

(trifluoromethy l)pheny 1] ethylideneamino] oxy methyl] phenyl] acetate or its agrochemically acceptable salts, esters and derivatives; and d) one or more agrochemically acceptable excipients.

In another embodiment of the present invention, the synergistic pesticidal composition comprises: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-85% by weight of the composition; b) Abamectin or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-85% by weight of the composition; and c) Compound of Formula I, i.e. methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3-

(trifluoromethy l)pheny 1] ethylideneamino] oxy methyl] phenyl] acetate or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-85% by weight of the composition.

In one another preferred embodiment of the present invention, the synergistic pesticidal composition comprises: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-85% by weight of the composition; b) Abamectin or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-85% by weight of the composition; c) Compound of Formula I, i.e. methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3-

(trifluoromethy l)pheny 1] ethylideneamino] oxy methyl] phenyl] acetate or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-85% by weight of the composition; and d) One or more agrochemically acceptable excipients.

In one another embodiment of the present invention, the synergistic pesticidal composition comprises: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-65% by weight of the composition b) Abamectin or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-65% by weight of the composition; and c) Compound of Formula I, i.e. methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3-

(trifluoromethy l)pheny 1] ethylideneamino] oxy methyl] phenyl] acetate or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-65% by weight of the composition.

In one another embodiment of the present invention, the synergistic pesticidal composition comprises: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-40% by weight of the composition; b) Abamectin or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-40% by weight of the composition; and c) Compound of Formula I, i.e. methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3-

(trifluoromethy l)pheny 1] ethylideneamino] oxy methyl] phenyl] acetate or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-40% by weight of the composition.

In an embodiment, the present invention provides a method of improving plant health and increasing crop yield by using synergistic pesticidal composition comprising: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives; b) Abamectin or its agrochemically acceptable salts, esters and derivatives; and c) a compound of Formula I, chemically known as methyl (2E)-2-methoxyimino-2-[2- [ [(E)- 1 - [3 -(trifluoromethyl)phenyl] ethylideneamino] oxymethyl] phenyl] acetate or its agrochemically acceptable salts, esters and derivatives.

In another embodiment of the present invention, there is also a process provided for the preparation of stable synergistic pesticidal composition comprising: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives; b) Abamectin or its agrochemically acceptable salts, esters and derivatives and c) a compound of Formula I, chemically known as methyl (2E)-2-methoxyimino-2-[2- [ [(E)- 1 - [3 -(trifluoromethyl)phenyl] ethylideneamino] oxymethyl] phenyl] acetate or its agrochemically acceptable salts, esters and derivatives.

In one embodiment of the present invention, the present pesticidal composition is stable and has enhanced shelf life.

In another aspect, the present invention provides a synergistic pesticidal composition for controlling various insect pests and fungus in field crops, and effective controlling wide range of insect pests or insect or nematicides or fungus.

In an aspect, the present invention provides a synergistic pesticidal composition which has enhanced efficacy and penetration capacity. DETAILED DESCRIPTION OF THE INVENTION

In describing the embodiments of the invention, specific terminology is resorted for sake of clarity. However, it is not intended that the invention be limited to specific terms so selected and it is to be understood that each specific term includes all technical equivalents that operate in a similar manner to accomplish a similar purpose.

Discussed below are some representative embodiments of the present invention. The invention in its broader aspects is not limited to the specific details and representative methods.

All technical and scientific terms used herein have the same meanings as commonly understood by someone ordinarily skilled in the art to which the present subject matter belongs.

The terminology used, in the present disclosure, is only for the purpose of explaining a particular embodiment and such terminology shall not be considered to limit the scope of the present disclosure.

The expression of various quantities in terms of “% w/w” or “%” means the percentage by weight, relative to the weight of the total formulation or composition unless otherwise specified.

The term “active ingredient” (a.i.) or “active agent” used herein refers to that component of the composition responsible for control and killing of insect pest and fungal diseases.

The terms “plants” and “vegetation” include, but are not limited to, germinant seeds, emerging seedlings, plants emerging from vegetative propagules, and established vegetation.

The term “crop” shall include a multitude of desired crop plants or an individual crop plant growing at a locus.

The term “synergistic”, as used herein, refers to the combined action of two or more active agents blended together and administered conjointly that is greater than the sum of their individual effects.

“Bioactive amounts” as mentioned herein means that amount which, when applied for treatment of crops, is sufficient to give effect in such treatment. The term “health of a plant” or “plant health” is defined as a condition of the plant and/or its products. As a result of the improved health; yield, plant vigour, quality and tolerance to abiotic or biotic stress is increased. As a result, the health of a plant is increased even in the absence of pest pressure.

Accordingly, in an especially preferred embodiment according to the invention, the health of a plant is increased both in the presence and absence of biotic or abiotic stress factors. An increase in plant vigor may for example result in an increased yield and/or tolerance to abiotic or biotic stress.

One indicator for the condition of the plant is the yield. “Yield” is to be understood as any plant product of economic value that is produced by the plant such as grains, fruits, vegetables, nuts, grains, seeds, wood (e.g. in the case of silviculture plants) or even flowers (e.g. in the case of gardening plants, ornamentals). The plant products may in addition be further utilized and/or processed after harvesting.

In an especially preferred embodiment of the invention, the yield of the treated plant is increased.

In another preferred embodiment of the invention, the yield of the plants treated according to the method of the invention, is increased synergistically.

In another especially preferred embodiment of the invention, the plant vigour of the treated plant is increased. In another preferred embodiment of the invention, the plant vigour of the plants treated according to the composition of the present invention is increased synergistically.

Another indicator for the condition of the plant is the “quality” of a plant and/or its products.

In an especially preferred embodiment of the invention, the quality of the treated plant is increased.

In another preferred embodiment of the invention, the quality of the plants treated according to the method of the invention, is increased synergistically. The present invention includes within its scope, all possible salts, esters and derivatives of the active ingredients of the composition.

It has been observed by the inventors of the present invention that the composition of present invention not only has enhanced bio-efficacy and provides synergistic effect but also gives control of pests and diseases caused by insect pests and fungi for a longer duration as compared to solo and binary formulations of insecticides and fungicides.

(trifluoromethyl)phenyl] ethylideneamino] oxymethyl] phenyl] acetate or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-85% by weight of the composition; and d) One or more agrochemically acceptable excipients.

In one another embodiment of the present invention, the synergistic pesticidal composition comprises: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-65% by weight of the composition; b) Abamectin or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-65% by weight of the composition; and c) Compound of Formula I, i.e. methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3-

In one another embodiment of the present invention, the synergistic pesticidal composition comprises: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-40 % by weight of the composition; b) Abamectin or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-40 % by weight of the composition; and c) Compound of Formula I, i.e. methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3-

(trifluoromethy l)pheny 1] ethylideneamino] oxy methyl] phenyl] acetate or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-40 % by weight of the composition

In an embodiment, the present invention provides a method of improving plant health and increasing crop yield by using synergistic pesticidal composition comprising: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives; b) Abamectin or its agrochemically acceptable salts, esters and derivatives and c) a compound of Formula I, chemically known as methyl (2E)-2-methoxyimino-2-[2- [ [(E)- 1 - [3 -(trifluoromethyl)phenyl] ethylideneamino] oxymethyl] phenyl] acetate or its agrochemically acceptable salts, esters and derivatives.

In accordance with an embodiment of the present invention, there is provided a synergistic pesticidal composition comprising active ingredients present in the weight % range as given below:

In one aspect/ another embodiment, the pesticidal composition of present invention can be applied to a plant/crop/soil by spraying, rubbing, atomizing, irrigating, evaporating, dusting, fogging, broadcasting, pouring, mist blowing, soil mixing, foaming, painting, spreading-on, drenching, dipping or drip irrigation, etc. In yet another embodiment of the present invention, the present pesticidal composition can be applied to various crops and plants including but not limited to Rice (Paddy), Cotton, Brinjal, Chilli, Ground nut (Seed Treatment), Tomato, cucurbits, lettuce, cabbage, carrots, cruciferous, Soybean, Cotton, Com, Banana, Chilli, Bitter gourd, Grape, Apple, Onion, Cucumber, Potatoes, Grapes, Mango, pepper, Pomegranate, Black gram, Cumin, Green gram, Soybean, Coffee, Tea, Maize, Chilli, barley, oats, sorghum, sunflowers, turf and forage, sugar beet, beans, peas and ornamentals, etc.

The most common pests and diseases controlled by composition of present invention include but not limited to Red spider mites (Tetranychus urticae), Mites, Seed and Seedling rot disease, Sheath blight, Leaf, Neck Blast, Glume discoloration (dirty panicle), Early blight, Powdery mildew, Anthracnose, Altemaria leaf spot, Yellow rust, Leaf hopper, Thrips, Fruit and Shoot Borer, Diamond Back Moth, yellow mites (Polyphagotarsonemus lotus), anthracnose (causal organism Colletotrichum spp.) Tobacco caterpillar, Semi looper, Tobacco caterpillar, Spotted pod Borer, Pod Borer, etc.

In one of the embodiments, the synergistic pesticidal composition of present invention is effective in controlling the growth of undesirable vegetation, e.g., in monocot and dicot crops including genetically modified and conventional or non-genetically modified varieties of Rose (Ornamental), Grapes (Vitis vinifera), Brinjal (Solanum melongena), Cabbage (Brassica oleracea), Chilli (Capsicum frutescens), Okra (Abelmoschus esculentus), Red-gram (Cajanus cajan), Tomato (Solarium lycopersicum), Rice (Paddy), Wheat (Triticum aeslivum). Mango (Mangifera indica), Groundnut (Arachis hypogaea). and Soyabean (Glycine max'), etc.

In yet another embodiment of the present invention, the present pesticidal composition can be formulated as one or more of Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Micro-emulsion (ME), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed formulation of CS and SC (ZC) or a mixed formulation of CS and SE (ZE) or a mixed formulation of CS and EW (ZW).

In yet another embodiment of the present invention, the synergistic pesticidal composition is formulated either as Suspension concentrate (SC) or Emulsifiable concentrate (EC) or Water dispersible granules (WG). The composition of the present invention are effective in controlling broad spectrum of pests, fungi in various plants/crops including but not limited to brown plant hopper, whiteflies, jassids, aphids, thrips, white backed plant hopper, green leaf hopper and leaf folder, bugs, rice ear headed bugs, stem borer, sheath blight, leaf blast, powdery mildew, Anthracnose/Fruit Rot, frog eye leaf spot (Cercospora)& alternaria leaf spot, tikka disease, alternaria leaf blight, turcicum leaf blight, sigatoka leaf spot, anthracnose, purple blotch, early blight, late blight, early blight, septoria leaf spot, frog eye leaf spot, alternaria blight, powdery mildew, yellow mite, cercospora leaf spot, rust, Fruit borer, collar rot, stem rot, loose smut, seed and seedling rot disease, glume discoloration (dirty panicle), fodder beet, oil seed rape, pansy, etc.

In another embodiment of the present invention, the synergistic pesticidal composition of the present invention further comprises one or more agrochemically acceptable excipients including but not limited to the group comprising surfactant(s), dispersing agent(s), antifreezing agent(s), emulsifier(s), anti-foaming agent/defoamer(s), wetting agent(s), antimicrobial/anti-bacterial agent(s), thickening agent/thickener(s), quick coating agent(s) or sticking agents/sticker(s), spreader(s), binder(s), pH-adjusting agent(s), anti-caking agent(s), adjuvant(s), filler(s)/suspension aid(s), colorant(s), carrier(s), buffering agent(s), rheology modifier(s), solvent(s), co-solvent(s) or a combination thereof. Additional components may also be included, e.g., protective colloids, carriers, adhesives, thixotropic agents, penetration agents, stabilisers, sequestering agents. More generally, the active materials can be combined with any solid or liquid carrier/additive, which complies with usual formulation techniques.

An adjuvant used in the present invention is any material that is added to an agrochemical formulation to enhance or modify the performance of the formulation. An adjuvant(s) used in the present invention to make it a safer to ecological environmental, having low toxicity and having no phytotoxicity effects on any part of the plant. Examples of surfactant(s) and/or dispersing agent(s) used herein include but not limited to polymeric anionic dispersant, polyarylphenyl ether phosphate, tristyryl phenol ethoxylate, Polymethyl methacrylate-polyethylene glycol graft copolymer, acrylate copolymer, acrylic graft copolymer, non-ionic proprietary surfactant, ethoxylated tristryl phenol Sulphate, alkyl naphthalene formaldehyde condensate , naphthalene sulfonic acid, sodium salt condensate with formaldehyde, ethoxylated oleyl cetyl alcohol, polyalkelene glycol ether, ethoxylated fatty alcohol, Sodium polymethyl methacrylate, sodium polyacrylate, sodium lignosulphonate, calcium lignosulphonate, alkylphenol polyoxyethylene ether, sodium salt of naphthalene sulfonate condensate, alkyl or polyalkyl naphthalene sulphonate, Sodium Alkylnaphthalene Sulfonate Formaldehyde Condensate, polycarboxylate or its sodium salt, fatty alcohol polyoxyethylene ether, alcohol polyglycol ether or mixtures thereof and present in the range of 0.1-20% by weight of the composition.

Examples of wetting agent(s) used herein include but not limited to tristyrylphenol ethoxylate non-ionic emulsifier, mixture of non-ionic surfactants, alkoxylated alcohol, block copolymer, alcohol polyglycol ether, alkyl olefin sulphates, dioctyl sulpho succinate, alkyl naphthalene sulphate, polyalkyl naphthalene sulphonate, alkyl phenol ethoxylates, tri-styrenated phenol ethoxylate, EO/PO block co-polymers, sodium lauryl sulphate, sodium ligno sulphates, Ethanol 2,2,2 -nitrilotris with alpha-(2,4,6-tris(l-phenylethyl)phenyl)- omega-hydroxypoly(oxy-l,2- ethanediyl) phosphate, Polyethylene Polypropylene glycol mono butyl ether , Alkyl phenol Polyethanoxy Ether, 2-2- oxydiethanol, Dihydrogen mono oxide or mixtures thereof and present in the range of 0.1-8.0 % by weight of the total composition.

Examples of anti-foaming agent/defoamer(s) used herein include but not limited to silicon emulsion based anti-foam agents, Siloxane polyalkyleneoxide, Polydimethylsiloxane emulsion, trisiloxane ethoxylates, silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane and mixtures thereof and present in the range of 0.1-5.0% by weight of the composition.

Examples of anti-freezing agent(s) used herein include but not limited to glycol, propylene glycol, mono ethylene glycol, Glycerol, glycerine, diethylene glycol, sorbitol, urea, mannitol, polyethylene glycol or mixtures thereof and present in the range of 0.1-12 % by weight of the composition.

Examples of antimicrobial/anti -bacterial agent(s) used herein include but not limited to 1,2- benzisothiazolin-3-one, formaldehyde, sodium benzoate/Sodium o-phenylphenate, 5-chloro-2- methyl-4-isothiazolin-3-one & 2- methyl-4-isothiazolin-3-one, potassium sorbate or mixtures thereof and present in the range of 0.01-8.0 % by weight of the composition.

Rheology modifiers are sometimes referred to as thickeners or thickening agents, but they do much more than just thicken a formulation. A good rheology modifier structures the formulation but when a force is applied it becomes flowable and easily poured. Examples of rheology modifier or thickening agent/thickener(s) used herein include but not limited to polysaccharides, carboxymethyl cellulose, bentonite clay, aluminium magnesium silicate, hydroxy propyl cellulose, xanthan gum, gum arabic, gaur gum, silica powder, carbomer, chitosan, precipitated silica or mixtures thereof and present in the range of 0.01-5.0 % by weight of the composition.

Examples of solvent(s) used herein include but not limited to heavy aromatic hydrocarbon, N- methyl pyrollidone (NMP), Di-methylsulfoxide (DMSO), Solvent C-IX, N- alcohol, alkyl amide, vegetable oil, mineral oil, distilled water, aromatic solvents, water or mixtures thereof and present in the range of 0.1-20 % by weight of the composition.

Examples of emulsifier(s) used herein include but not limited to nonionic surfactant of ethoxylated fatty acid type, such as ethoxylated fatty acid mono-, di- or triglycerides or ethoxylated dialkyl sulfosuccinate, Tri-styrenated phenol ethoxylate , Emulsifier (Blend of Anionic and Non-ionic), blend of Calcium Alkyl benzene sulphonate and Tri-styrenated phenol ethxylate an alkylaryl sulfonate, a polyoxyethylene fatty acid ester, a polyoxyethylene sorbitol fatty acid ester, a polyoxyethylene castor oil and a polyoxyethylene hydrogenated castor oil., ethoxylated fatty alcohol type or a block copolymer comprising one or more alkylene oxide block type or mixtures thereof and present in the range of 0.1-25 % by weight of the composition. In an embodiment, the kit-of-parts comprises an instructions manual, said instructions manual comprising instructions directing a user to ad-mix the components before being used.

Thus, before describing the present invention in detail, it is to be understood that this invention is not limited to particularly exemplified systems or process parameters that may of course, vary. It is also to be understood that the terminology used herein is for the purpose of describing particular embodiments of the invention only and is not intended to limit the scope of the invention in any manner. The use of examples anywhere in this specification including examples of any terms discussed herein is illustrative only, and in no way limits the scope and meaning of the invention or of any exemplified term. Likewise, the invention is not limited to various embodiments given in this specification. Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. In the case of conflict, the present document, including definitions will control.

The composition of the present invention can also comprise or may be applied together and/or sequentially with further active compounds. These further compounds can be selected from fertilizers or micronutrient donors or microorganisms or other preparations that influence plant growth, such as inoculants (e.g., a strain of nitrogen-fixing bacteria), and plant inducers.

In an embodiment, the present invention provides, a stable synergistic pesticidal composition comprising: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives; b) Abamectin or its agrochemically acceptable salts, esters and derivatives; and c) Compound of Formula I, chemically known as methyl (2E)-2-methoxyimino-2-[2- [ [(E)- 1 - [3 -(trifluoromethyl)phenyl] ethylideneamino] oxymethyl] phenyl] acetate or its agrochemically acceptable salts, esters and derivatives.

In another embodiment, the stable synergistic pesticidal composition comprising: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-85% by weight of the composition; b) Abamectin or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-85% by weight of the composition; and c) Compound of Formula I, i.e. methyl (2E)-2-methoxyimino-2-[2-[[€-l-[3-

In another embodiment, the present invention provides a method for controlling a plant disease caused by a plant-pathogens comprising applying to the plant or portion thereof or soil, a pesticidal effective amount of the pesticidal composition of the present invention.

In another embodiment, the stable synergistic pesticidal composition further comprises one or more agrochemically acceptable excipients.

In another embodiment, the use of said composition promotes plant health and improves crop yield.

In another embodiment, the stable synergistic pesticidal composition provide one shot application of novel and effective synergistic pesticidal composition for controlling harmful pests in plants including brinjal, chilli, cabbage, okra, red-gram, tomato, rose grapes, rice wheat etc.

In still another embodiment, the present invention provides a kit-of-parts comprising a plurality of components, wherein said plurality of components comprises: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives; b) Abamectin or its agrochemically acceptable salts, esters and derivatives; and c) Compound of Formula I, chemically known as methyl (2E)-2-methoxyimino-2-[2- [ [(E)- 1 - [3 -(trifluoromethyl)phenyl] ethylideneamino] oxymethyl] phenyl] acetate or its agrochemically acceptable salts, esters and derivatives.

The present invention includes within its scope, all possible salts, esters and derivatives of the active ingredients of the composition.

The composition of present invention not only has enhanced bio-efficacy and provides synergistic effect but also gives control of insects-pest and fungal diseases for a longer duration as compared to solo and binary formulations of pesticides.

The composition of the present invention is effective in controlling broad spectrum of insect but not limited to brown plant hopper, whiteflies, jassids, aphids, thrips, white backed plant hopper, green leaf hopper and leaf folder, bugs, rice ear headed bugs, stem borer, sheath blight, leaf blast, powdery mildew, Anthracnose/Fruit Rot, frog eye leaf spot (Cercospora)& alternaria leaf spot, tikka disease, alternaria leaf blight, turcicum leaf blight, sigatoka leaf spot, anthracnose, purple blotch, early blight, late blight, early blight, septoria leaf spot, frog eye leaf spot, alternaria blight, powdery mildew, yellow mite, cercospora leaf spot, rust, fruit borer, collar rot, stem rot, loose smut, seed and seedling rot disease, glume discoloration (dirty panicle), fodder beet, oil seed rape, pansy, etc. including pest and fungus resistant to chemicals, and shows excellent controlling effects (synergistic controlling effects) which could never be expected from a single component alone.

In one embodiment, the composition according to the present invention acts synergistically to control pests in various crops.

Through the pesticidal composition of present invention, the number of applications to control wide range of insect-pests and fungal diseases appearing at the same time is minimised. The composition of present invention is highly safe to the user and to the environment. The composition offers the user a single homogenous application eliminating the need for tank mix. The composition also is cost-effective as it provides much greater simultaneous control and can be used in a variety of crops with a broader spectrum of protection.

Representative examples of the present composition of this invention are provided below and are not to be construed as limiting in any manner:

Examples: General Recipe of composition of present invention:

Example 1. Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula I 17.5% SC

CHEMICAL COMPOSITION:

FORMULATION PROCESS:

1. The mixture of surfactants (Acrylic graft copolymer, Non-ionic proprietary surfactant, Poly alkyl naphthalene sulphonate), Poly dimethylsiloxane emulsion & Propylene Glycol (PG) were first diluted in required D.M. Water, and then solubilized by high shear mixing.

2. Then to the above solution added Fluxametamide Technical, Abamectin Technical, and Compound of formula I Technical mix to make homogeneous mass.

3. Then the above mixed mass was grinded in Bead Mill. Grinding was carried out until a mean particle size of below 5 microns was obtained.

4. Then Prepared 2% gum solution by taking 100 g DM water and then added 0.2 g of 1,2- Benzisothiazolin-3-one. To this solution added 2 g xanthan gum.

5. To the above grinded mass, added 2% water solution of xanthan gum under low stirring and then mixed well till the homogeneous solution is obtained.

6. Finally checked for quality parameters. STABILITY DATA:_ Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula I 17.5% SC

Example 2. Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula I 17.5% EC

CHEMICAL COMPOSITION:

FORMULATION PROCESS:

1. Charged the solvent into a reactor fitted with propeller type stirrer and start the mixing at 30 rpm.

2. Then added solvent N-Methyl Pyrolidone (NMP) and mixed for 15 min at same rpm.

3. To the above solution, then added Fluxametamide Technical, Abamectin Technical, and Compound of formula I Technicals and mixed well.

4. Further, added emulsifier to the above solution and mixed well.

5. Finally send the sample to QC for complete analysis.

STABILITY DATA: Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula I 17.5% EC

Example 3. Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula I 17.5% WG

CHEMICAL COMPOSITION: PREPARATION PROCESS:

A. Formulation process

1. Took China Clay in the ribbon blender and started mixing. To this added silica powder, Acrylate Copolymer, Sodium Alkylnaphthalene Sulfonate Formaldehyde Condensate, Sodium Polycarboxylate, Fluxametamide technical, Abamectin technical and Compound of formula I technical and mixed well.

2. Continued to mix this till the material was completely homogenised.

B. Grinding process

1. Allowed to pass the premix through the Air jet mill at 6 to 7 kg/cm² of grinding pressure and 100 to 150 kg/ hr feeding rate so as get a particle size of D90 less than 10 micron. The grinded material was collected in post blender.

2. WP is then checked for Al content and suspensibility parameter.

3. After approval from QC the process was taken further for extrusion and drying.

C. Extrusion process

1. Into the post blender the solution of water and Polydimethyl siloxane was added by means of spraying and dough was prepared. This dough was mixed well to get a well hydrated dough for extrusion.

2. This dough was then allowed to pass through the screw valve fitted with post blender and then passed through basket extruder (Sieve size of 0.8 mm / 1.0 mm).

D. Drying Process

1. These wet extruded granules were then passed through VFBG (vibro fluid bed drier) which is brought to a consistent temperature of 50°C prior to drying of wet granules.

2. These granules were checked for moisture content which should not more than 3%.

3. Once the parameter got set then the process is continued.

E. Sieving and packing

The dried granule were passed through vibro siever machine to separate any lumps or dust and desired size granules were collected and packed.

STABILITY DATA: Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula I 17.5% WG

Evaluation of synergistic effect of pesticidal composition of the present invention

A synergistic effect of two or more products exists whenever the action of an active ingredient combination is greater than the sum of the actions of the individual components. Synergism was calculated by using Colby’s method (Weeds, vol. 15 No. 1 (Jan 1967), pp. 20-2.

The synergistic action expected for a given combination of two active components can be calculated as follows:

XY

E = (X + Y) - -

100

The synergistic action expected for a given combination of three active components can be calculated as follows:

(XY+YZ+XZ) (XYZ)

E = (X + Y + Z) - - + -

100 10000

Where:

E represents expected percentage of pesticidal control for the combination of the two or three actives ingredients at defined doses (for example equal to x, y and z, respectively). X is the percentage of pesticidal control observed by the compound (Fluxametamide) at a defined dose (equal to x).

Y is the percentage of pesticidal control observed by the compound (Abamectin) at a defined dose (equal to y).

Z is the percentage of pesticidal control observed by the compound (Compound of formula I) at a defined dose (equal to z).

When the percentage of pesticidal control observed for the combination is greater than the expected percentage, there is a synergism effect.

Observed control (%) Ratio = -

Expected control (%)

Ratio of O/E > 1, synergism observed

The present invention is illustrated by way of examples, the examples are meant for illustrative purposes and should not be construed as limiting.

Experiment for Synergistic activity of composition of present invention:

Example 1- Details of experiment on chilli crop:

Field experiment for synergistic activity of Fluxametamide, Abamectin & Compound of formula I for the control of pests and diseases in chilli crop was conducted.

To evaluate the synergistic effect, chilli (Variety: Kashi Anmol) crop was sown in 6 m x 5 m plots maintaining 50 cm x 25 cm plant distance with three replications and in Randomized Block Design (RBD). The treatments were applied as foliar spray in the form of SC formulation @ 500 ml/ha. Each active component was applied twice in different ternary and binary compositions. Solo compositions were also taken for comparison. The treatment details are as under:

The treatments T1 to T28 were used as foliar application whereas no treatment was done for T29 control treatment. Two applications at 15 days interval were done of all treatments on the appearance of Insect and disease at experimental plots. Observations for fruit borer was recorded at before spray & 14 days after 1^st and 2^nd application by observing 5 random plants per plot and number of fruit borer per plant was calculated. Furthermore, the observations for anthracnose disease (causal organism Colletotrichum spp.) were recorded at before spray and 14 days after 1^st and 2^nd application by observing 5 random plants per plot and per cent disease incidence was calculated. The per cent reduction in fruit borer and per cent disease incidence was calculated over control. Based on the per cent reduction at 14 days after second spray in fruit borer and per cent disease incidence, the Expected control was calculated and compared with Observed control. The results of the trial have been presented here under in Table 1.

Table 1: Synergistic effect of composition of the present invention (Fluxametamide + Abamectin + Compound of formula I) against fruit borer and disease incidence in chilli crop

It is clearly evident from the data shown in above Table 1 for per cent fruit borer control and anthracnose disease control in chilli crop that the ternary composition of the present invention comprising Fluxametamide, Abamectin, Compound of formula I i.e. T1 to T4 are synergistic for both fruit borer and anthracnose disease control with > 1 Colby’s Ratio. The binary combinations of two pesticides (Fluxametamide + Abamectin, Fluxametamide + Compound of formula I and Abamectin + Compound of formula I) T5 to T16 were compatible but no synergistic effect was observed for the control of fruit borer and disease. All solo products and market samples were also less effective for the control of both insect-pest as compared to ternary composition of the present invention.

Experiment for Bio-efficacy evaluation of composition of present invention:

For the ternary and binary composition based on Fluxametamide, Abamectin and Compound of formula I evaluation under field conditions, the basic test composition as Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula I 17.5% SC was manufactured specifically by the inventor. For ternary composition, Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula 1 17.5% SC was used and for binary compositions, Fluxametamide 7.6% + Abamectin 1.9% SC, Fluxametamide 7.6% + Compound of formula I 17.5% SC, Abamectin 1.9% + Compound of formula 1 17.5% SC were used. The solo formulations of Fluxametamide 7.6% SC, Abamectin 1.9% SC and Compound of formula I 17.5% SC were also used for comparison along with control treatment. Furthermore, standard checks available in the market, Fluxametamide 10% EC, Chlorantraniliprole 4.3% +Abamectin 1.7% SC and Tebuconazole 50% + Compound of formula I 25% WG were also included in the study.

Example 2: Evaluation of the combination product of the present invention on chilli

The synergistic composition of the present invention Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula I 17.5% SC was evaluated on chilli crop. The crop sowing was done in Randomized Block Design (RBD) with three replications maintaining a distance of 50 cm x 25 cm between plants and rows.

The observations were recorded for the following objectives.

Objectives: 1. Bio-efficacy evaluation against fruit borer on chilli crop

2. Bio-efficacy evaluation against yellow mite on chilli crop

3. Bio-efficacy evaluation against anthracnose disease incidence on chilli crop

4. Bio-efficacy evaluation based on per cent reduction in fruit borer over control

5. Bio-efficacy evaluation based on percent reduction in yellow mite population over control

6. Bio-efficacy evaluation based on percent reduction in anthracnose disease incidence over control

7. Bio-efficacy evaluation based on crop yield.

Treatment details:

Methodology:

The treatments T1 to T15 and T17 were used as foliar application whereas no treatment was done for T 16 i.e., control treatment. All treatments were applied at the time of initiation of pest in the experimental plots.

The Observations for fruit borer was recorded at before spray & 14 days after 1^st and 2^nd application by observing 5 random plants per plot and number of fruit borer per plant was calculated. The observations for yellow mites (Polyphagotarsonemus latus) population at before spray and 14 days after 1^st and 2^nd application were recorded on 3 leaves of 5 randomly selected plants per plot. Furthermore, the observations for anthracnose (causal organism Colletotrichum spp.) were recorded at before spray and 14 days after 1^st and 2^nd application by observing 5 random plants per plot and per cent disease incidence was calculated. The per cent reduction in fruit borer, yellow mite population and per cent anthracnose disease incidence was calculated over control. The crop yield was recorded at crop harvest. The observations for phytotoxicity on chilli crop at 1, 3, 7, 10 and 14 days after both applications were also recorded. Results are presented in Table 2, 3, 4, 5 and 6.

Results:

Table 2: Field bio-efficacy evaluation of Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula 1 17.5 % SC against fruit borer in chilli crop. CD (p=0.05) _ | 0.06 | 0.09 | - |

Figures in parentheses are sq. root transformed values; NS= non- significant

Table 3: Field bio-efficacy evaluation of Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula 1 17.5% SC against yellow mite in chilli crop.

Figures in parentheses are square root transformed values; NS= Non significant

Table 4: Field bio-efficacy evaluation of Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula

1 17.5% SC against anthracnose disease in chilli crop

Figures in parentheses are angular transformed values; NS= Non significant

Table 5: Field bio-efficacy evaluation of Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula 1 17.5% SC based on yield of chilli crop.

Table 6: Phytotoxicity evaluation of Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula I 17.5% SC on chilli crop

From the example, it can be clearly seen that the composition of the present invention is superior for controlling the fruit borer at 14 days after application (Table 2), yellow mites (Polyphagotarsonamus latus) at 14 days after both applications (Table 3) and anthracnose disease after 14 days of treatment in chilli crop (Table 4) as compared to the other binary and solo compositions. The yield of chilli crop also improved in the ternary composition of Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula I 17.5% SC as compared to binary and solo compositions (Table 5).

The disclosed composition Fluxametamide 7.6% + Abamectin 1.9% + Compound of formula I 17.5% SC @ 400, 500ml, 600 ml and 1000 ml/ha further showed no phyto toxicity in the chilli crop even after 1, 3, 7, 10 and 14 days after 1^st spray (Table 6).

It is evident from the above data that the composition of the present invention i.e., Fluxametamide + Abamectin + Compound of formula I SC resulted in good control of fruit borer, yellow mite and anthracnose in chilli with higher respective yields as compared to the reference standard products (binary compositions, solo products and market standards). Hence, the composition of present invention has resulted in synergistic effect and is bio-efficacious. Through the pesticidal composition of present invention, the number of applications to control wide range of pests appearing at the same time is minimised. The composition of present invention is highly safe to the user and to the environment. The composition offers the user a single homogenous application eliminating the need for tank mix. The composition also is cost- effective as it provides much greater simultaneous control and can be used in a variety of crops with a broader spectrum of protection.

In particular, it has now been found, surprisingly that, for example, the pesticidal activity of the composition of present invention, compared with the pesticidal activity of individual components, is synergistic. In fact, various advantageous properties associated with the compositions according to the invention, include but are not limited to: a broadening of the spectrum of pesticidal activity to other pests, for example to resistant strains; a reduction in the rate of application of the active ingredients; adequate control of the pests at a rate of application at which the individual compounds are not very effective, advantageous behaviour during formulating and/or upon application, improved stability, improved crop characteristics including crop yields, more developed root system, increase in plant health including height, improved plant vigor, less plant verse (lodging), and other advantages familiar to a person skilled in the art.

From the above investigations, it will be observed that numerous modifications and variations can be effectuated without departing from the true spirit and scope of the novel concepts of the present invention. It is to be understood that no limitations with respect to the specific embodiments illustrated is intended or should be inferred. It should be understood that all such modifications and improvements have been deleted herein for the sake of conciseness and readability but are properly within the scope of the following claims.

Claims

I CLAIM:

[CLAIM 1]. A stable synergistic pesticidal composition comprising: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives; b) Abamectin or its agrochemically acceptable salts, esters and derivatives; and c) Compound of Formula I, i.e. methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3-

(trifluoromethyl)phenyl]ethylideneamino]oxymethyl]phenyl] acetate or its agrochemically acceptable salts, esters and derivatives.

[CLAIM 2]. The stable synergistic pesticidal composition as claimed in claim 1, comprising: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives, in the range of 0.1-85% by weight of the composition; b) Abamectin or its agrochemically acceptable salts, esters and derivatives, in the range of 0.1-85% by weight of the composition; and c) Compound of Formula I, i.e. methyl (2E)-2-methoxyimino-2-[2-[[€-l-[3-

[CLAIM 3]. The stable synergistic pesticidal composition as claimed in claims 1 to 2, which further comprises one or more agrochemically acceptable excipients.

[CLAIM 4]. The pesticidal composition as claimed in claim 3 wherein the agrochemically acceptable excipients comprise of surfactant(s), dispersing agent(s), co-dispersant, antifreezing agent(s), emulsifier(s) (anionic and non-ionic), anti-foaming agent/defoamer(s), wetting agent(s), biocide/antimicrobial/anti-bacterial agent(s), thickening agent/thickener(s), quick coating agent(s) or sticking agents/sticker(s), spreader(s), binder(s), pH-adjusting agent(s), anti-caking agent(s), adjuvant(s), filler(s)/suspension aid(s), colorant(s), carrier(s), buffering agent(s), polymer(s), rheology modifier(s), solvent(s), co-solvent(s) or a combination thereof.

[CLAIM 5]. The stable synergistic pesticidal composition as claimed in claim 4, wherein the surfactant(s) and/or dispersing agent(s) is/are selected from the group comprising polymeric anionic dispersant, polyarylphenyl ether phosphate, tristyryl phenol ethoxylate, Polymethyl methacrylate-polyethylene glycol graft copolymer, acrylate copolymer, acrylic graft copolymer, non-ionic proprietary surfactant, ethoxylated tristryl phenol Sulphate, alkyl naphthalene formaldehyde condensate , naphthalene sulfonic acid, sodium salt condensate with formaldehyde, ethoxylated oleyl cetyl alcohol, polyalkelene glycol ether, ethoxylated fatty alcohol, Sodium polymethyl methacrylate, sodium polyacrylate, sodium lignosulphonate, calcium lignosulphonate, alkylphenol polyoxyethylene ether, sodium salt of naphthalene sulfonate condensate, alkyl or polyalkyl naphthalene sulphonate, Sodium Alkylnaphthalene Sulfonate Formaldehyde Condensate, polycarboxylate, or its sodium salt, fatty alcohol polyoxyethylene ether, alcohol polyglycol ether or mixtures thereof and present in the range of 0.1-20% by weight of the composition.

[CLAIM 6]. The stable synergistic pesticidal composition as claimed in claim 4, wherein the wetting agent(s) is selected form the group comprising tristyrylphenol ethoxylate non-ionic emulsifier, mixture of non-ionic surfactants, alkoxylated alcohol, block copolymer, alcohol polyglycol ether, alkyl olefin sulphates, dioctyl sulpho succinate, alkyl naphthalene sulphate, polyalkyl naphthalene sulphonate, alkyl phenol ethoxylates, tri-styrenated phenol ethoxylate, EO/PO block co-polymers, sodium lauryl sulphate, sodium ligno sulphates, Ethanol 2,2,2 - nitrilotris with alpha-(2,4,6-tris(l-phenylethyl)phenyl)- omega-hydroxypoly(oxy-l,2- ethanediyl) phosphate, Polyethylene Polypropylene glycol mono butyl ether , Alkyl phenol Polyethanoxy Ether, 2-2- oxydiethanol, Dihydrogen mono oxide or mixtures thereof and present in the range of 0.1-8.0 % by weight of the total composition.

[CLAIM 7]. The stable synergistic pesticidal composition as claimed in claim 4, wherein the anti-foaming agent/defoamer(s) is/are selected from the group comprising silicon emulsion based anti-foam agents, Siloxane polyalkyleneoxide, Polydimethylsiloxane emulsion, trisiloxane ethoxylates, silicone oil, silicone compound, C10~C20 saturated fat acid compounds or C8~C10 aliphatic alcohols compound, vegetable oil based antifoam, tallow based fatty acids, polyalkyleneoxide modified polydimethylsiloxane and mixtures thereof and present in the range of 0.1-5.0% by weight of the composition.

[CLAIM 8]. The stable synergistic pesticidal composition as claimed in claim 4, wherein the anti-freezing agent(s) is selected from the group comprising glycol, propylene glycol, mono ethylene glycol, Glycerol, glycerine, diethylene glycol, sorbitol, urea, mannitol, polyethylene glycol or mixtures thereof and present in the range of 0.1-12 % by weight of the composition.

[CLAIM 9]. The stable synergistic pesticidal composition as claimed in claim 4, wherein the antimicrobial/anti-bacterial agent(s) is/are selected from the group comprising 1,2- benzisothiazolin-3-one, formaldehyde, sodium benzoate/Sodium o-phenylphenate, 5-chloro-2- methyl-4-isothiazolin-3-one & 2- methyl-4-isothiazolin-3-one, potassium sorbate or mixtures thereof and present in the range of 0.01-8.0 % by weight of the composition.

[CLAIM 10]. The stable synergistic pesticidal composition as claimed in claim 4, wherein rheology modifier or thickening agent/thickener(s) is/are selected from the group comprising polysaccharides, carboxymethyl cellulose, bentonite clay, aluminium magnesium silicate, hydroxy propyl cellulose, xanthan gum, gum arabic, gaur gum, silica powder, carbomer, chitosan, precipitated silica or mixtures thereof and present in the range of 0.01-5.0 % by weight of the composition.

[CLAIM 11]. The stable synergistic pesticidal composition as claimed in claim 4, wherein the solvent(s) is selected from the group comprising heavy aromatic hydrocarbon, N-methyl pyrollidone(NMP), Di-methyl sulfoxide(DMSO), Solvent C-IX, N- alcohol, alkyl amide, vegetable oil, mineral oil, distilled water, aromatic solvents, water or mixtures thereof and present in the range of 0.1-20 % by weight of the composition.

[CLAIM 12]. The stable synergistic pesticidal composition as claimed in claim 4, wherein the emulsifier is selected from the group consisting of a nonionic surfactant of ethoxylated fatty acid type, such as ethoxylated fatty acid mono-, di- or triglycerides or ethoxylated dialkyl sulfosuccinate, Tri-styrenated phenol ethoxylate , Emulsifier (Blend of Anionic and Nonionic), blend of Calcium Alkyl benzene sulphonate and Tri-styrenated phenol ethxylate an alkylaryl sulfonate, a polyoxyethylene fatty acid ester, a polyoxyethylene sorbitol fatty acid ester, a polyoxyethylene castor oil and a polyoxyethylene hydrogenated castor oil., ethoxylated fatty alcohol type or a block copolymer comprising one or more alkylene oxide block type or mixtures thereof and present in the range of 0.1-25 % by weight of the composition.

[CLAIM 13]. The stable synergistic pesticidal composition as claimed in claim 1-12, wherein the use of said composition promotes plant health and improves crop yield.

[CLAIM 14]. The stable synergistic pesticidal composition as claimed in claim 1-13, provide one shot application of novel and effective synergistic pesticidal composition for controlling harmful pests in plants including brinjal, chilli, cabbage, okra, red-gram, tomato, rose grapes, rice wheat etc.

[CLAIM 15]. The stable synergistic pesticidal composition as claimed in any one of the claims 1-14, wherein the composition is in form of Capsule suspension (CS), Dispersible concentrate (DC), Dustable powder (DP), Powder for dry seed treatment (DS), Emulsifiable concentrate (EC), Emulsifiable granule (EG), Emulsion water-in-oil (EO), Emulsifiable powder (EP), Emulsion for seed treatment (ES), Emulsion oil-in-water (EW), Flowable concentrate for seed treatment (FS), Granules (GR), Micro-emulsion (ME), Oil-dispersion (OD), Oil miscible flowable concentrate (OF), Oil miscible liquid (OL), Oil dispersible powder (OP), Suspension concentrate (SC), Suspension concentrate for direct application (SD), Suspo-emulsion (SE), Water soluble granule (SG), Soluble concentrate (SL), Spreading oil (SO), Water soluble powder (SP), Water soluble tablet (ST), Ultra-low volume (ULV) suspension, Tablet (TB), Ultra-low volume (ULV) liquid, Water dispersible granules (WG), Wettable powder (WP), Water dispersible powder for slurry seed treatment (WS), Water dispersible tablet (WT), a mixed composition of CS and SC (ZC), a mixed composition of CS and SE (ZE) or a mixed composition of CS and EW (ZW).

[CLAIM 16]. A kit-of-parts comprising a plurality of components, wherein said plurality of components comprises: a) Fluxametamide or its agrochemically acceptable salts, esters or its derivatives; b) Abamectin or its agrochemically acceptable salts, esters and derivatives; and c) Compound of Formula I i.e. methyl (2E)-2-methoxyimino-2-[2-[[(E)-l-[3-

[CLAIM 17]. A method for controlling a plant disease caused by a plant-pathogens comprising applying to the plant or portion thereof or soil, a pesticidal effective amount of the pesticidal composition as claimed in any one of the claims 1 - 16.

[CLAIM 18]. A process for preparing a stable synergistic pesticidal composition as claimed in claims 1-16.