WO2025156135A1

WO2025156135A1 - Led cartridge

Info

Publication number: WO2025156135A1
Application number: PCT/CN2024/073761
Authority: WO
Inventors: Chunyao LU; Chengda YE
Original assignee: LOreal SA
Current assignee: LOreal SA
Priority date: 2024-01-24
Filing date: 2024-01-24
Publication date: 2025-07-31
Anticipated expiration: 2026-07-24
Also published as: FR3158430A3

Abstract

A cartridge for treating skin and transdermal delivery, including a microneedle plane including one or more microneedles, configured to prepare the skin to provide a treatment, a light source configured to apply a light treatment, one or more sensors configured to measure one or more cartridge data, and a chip configured to collect the one or more cartridge data. Further, an applicator including a cartridge configured to removably couple to the applicator, including a microneedle plane including one or more microneedles, configured to prepare the skin to provide a microneedle treatment, a light source configured to apply a light treatment, one or more sensors configured to measure one or more cartridge data, and a chip configured to collect the one or more cartridge data.

Description

LED CARTRIDGE

SUMMARY

Disclosed herein is a cartridge for treating skin and transdermal delivery, including a microneedle plane including one or more microneedles, configured to prepare the skin to provide a treatment, a light source configured to apply a light treatment, one or more sensors configured to measure one or more cartridge data, and a chip configured to collect the one or more cartridge data.

In some embodiments, the chip is a near field communication (NFC) tag. In some embodiments, the chip is a microcontroller unit (MCU) tag. In some embodiments, the chip is an optical recognition sensor. In some embodiments, the chip is an optical recognition sensor.

In some embodiments, the cartridge further comprises a cap configured to cover the one or more microneedles. In some embodiments, the one or more sensors is a humidity sensor, a pressure sensor, a temperature sensor, an optical sensor, or a combination thereof.

In some embodiments, the one or more cartridge data is a change in humidity of the skin, a pressure level of the cartridge, a change in temperature of the skin, a change of color of the skin, or a combination thereof.

In some embodiments, the one or more microneedles are arranged in an array on the microneedle plane. In some embodiments, the light source is disposed in a center of the microneedle plane. In some embodiments, the light source is configured to apply blue light, red light, or near infrared (NIR) light.

Also disclosed herein is an applicator including a cartridge configured to removably couple to the applicator, including a microneedle plane including one or more microneedles, configured to prepare the skin to provide a microneedle treatment, a light source configured to apply a light treatment, one or more sensors configured to measure one or more cartridge data, and a chip configured to collect the one or more cartridge data.

In some embodiments, the applicator includes a spring disposed inside an interface of the applicator, and a plug configured to couple to the cartridge, where the spring and the plug together comprise a twist-push mechanism configured to couple and remove the cartridge from the applicator.

In some embodiments, the applicator further comprises a cap configured to cover the one or more microneedles. In some embodiments, the chip is a near filed communication (NFC) tag. In some embodiments, the chip is a microcontroller unit (MCU) tag.

In some embodiments, the one or more sensors is a humidity sensor, a pressure sensor, a temperature sensor, an optical sensor, or a combination thereof.

Also disclosed herein is a method of safely applying a microneedle treatment to skin, the method including contacting the skin with a microneedle plane of an applicator, preparing the skin with one or more microneedles, applying a light treatment with a light source, and measuring one or more cartridge data with one or more sensors on the cartridge.

In some embodiments, the method further includes applying the light treatment simultaneously with the preparing of the skin. In some embodiments, the light treatment comprises a blue light treatment. In some embodiments, the light treatment comprises a red light treatment. In some embodiments, the light treatment comprises a near infrared (NIR) light treatment.

This summary is provided to introduce a selection of concepts in a simplified form that are further described below in the Detailed Description. This summary is not intended to identify key features of the claimed subject matter, nor is it intended to be used as an aid in determining the scope of the claimed subject matter.

DESCRIPTION OF THE DRAWINGS

The foregoing aspects and many of the attendant advantages of this invention will become more readily appreciated as the same become better understood by reference to the following detailed description, when taken in conjunction with the accompanying drawings, wherein:

FIGURE 1A is a perspective view of an example applicator, in accordance with the present technology;

FIGURE 1B is an exploded view of the applicator of FIG. 1A, in accordance with the present technology;

FIGURE 2A-2B are closeup views of an example applicator with a removable cartridge, in accordance with the present technology;

FIGURE 3 is a close-up view of an example applicator with a cap, in accordance with the present technology;

FIGURE 4A is an internal cross-sectional view of an example applicator, in accordance with the present technology;

FIGURE 4B is the chip of the example applicator of FIG. 4A, in accordance with the present technology;

FIGURE 5 is an example applicator in use, in accordance with the present technology;

FIGURE 6 is an example microneedle plane, in accordance with the present technology; and

FIGURE 7 is an example method of applying microneedle treatment and light treatment, in accordance with the present technology.

DETAILED DESCRIPTION

Microneedling is a cosmetic procedure that encourages collagen production using tiny, sterilized needles. It may help smooth, firm, and tone skin and improve the appearance of scars, acne, and wrinkles. Further, LED (light-emitting diode) light therapy is a non-invasive treatment that enters the skin’s layers to improve the skin. LED light therapy treats various skin conditions and concerns, such as acne, fine lines and psoriasis. It comes in different types, including red light LED therapy, blue light LED therapy, ultraviolet (UV) light therapy, and near infrared (NIR) light therapy, which are sometimes used in combination.

Disclosed herein are applicators, systems, and methods for providing microneedle treatment (or therapy) . In some embodiments, the applicator includes a removeable cartridge, having a microneedle plane with one or more microneedles. The cartridge may also include a chip configured to collect data from one or more sensors located on the cartridge. In some embodiments, the one or more sensors may include a light source, such as an LED light source, configured to administer light therapy. In some embodiments, the light therapy may be administered sequentially or simultaneously with the microneedle therapy.

FIG. 1A is a perspective view of an example applicator 100, in accordance with the present technology. In some embodiments, the applicator 100 includes a body 105, an actuator 115, an electrical port 107, and a button 110. In some embodiments, the applicator further includes an interface 120 configured to couple to a removable cartridge 125. In some embodiments, the cartridge 125 is removably coupled to the applicator 100. In this manner, the cartridge 125 may be removed for cleaning, or be replaced to ensure that the cartridge 125 is sanitary.

In some embodiments, the body 120 is substantially cylindrical, but the body 120 may take any form factor. In some embodiments, the body 120 is longer than it is wide, to allow a user to hold the body 120 like a writing instrument. In some embodiments, the body 120 is organically shaped, such as shown in FIG. 1A. In some embodiments, the body 120 has a first end including an electrical port 107, and a second end configured to couple with the removable cartridge 120.

In some embodiments, the electrical port 107 is electrically coupled to a battery (as shown and described in FIG. 1B) located inside the applicator 100. In some embodiments, the electrical port 107 is configured to facilitate an electrical connection between the battery and a charging device or outlet. In some embodiments, this may be facilitated with a cable or wire. In some embodiments, the electrical port 107 powers the applicator 100. In some embodiments, the electrical port 107 may charge the battery of the applicator 100, and the device may function even when not coupled to an outlet or charging device.

In some embodiments, the applicator 100 includes a button 110. In some embodiments, the button 110 is configured to turn the applicator 100 on and/or off. In some embodiments, the button 110 may be used to facilitate a wireless connection (such as a Bluetooth^TM, Wi-Fi, or Zigbee) with another device, such as a smart device (as shown and described in FIG. 7) . In some embodiments, button 110 may begin or stop therapy, as described herein.

In some embodiments, actuator 112 may begin or stop therapy (also referred to herein as microneedle therapy or microneedle treatment) , as described herein. In some embodiments, actuator 112 may increase or decrease the intensity of therapy. In some embodiments, the actuator 112 may be a button, a touch-type capacitance button, a switch, or the like.

In operation, the applicator 100 is charged or powered with the electrical port 107. In some embodiments, button 110 may be pressed or actuated to turn the applicator 100 on. In some embodiments, a user may place a microneedle plane (such as microneedle plane 130, as shown in FIG. 1B) onto their skin. In some embodiments, the user may then press or otherwise actuate the actuator 112 to begin microneedle therapy as the user moves the applicator 100 over their skin. In some embodiments, the microneedle plane includes one or more microneedles (as shown in FIG. 6) . As the user moves the applicator 100 over their skin, the one or more microneedles prepare the user’s skin to provide the microneedle therapy. As used herein, the term “prepare” means to penetrate the skin, exfoliate the skin, or otherwise disrupt the skin barrier.

FIG. 1B is an exploded view of the applicator 100 of FIG. 1A, in accordance with the present technology. As explained above, in some embodiments, the applicator 100 includes an electrical port 107, a button 110, a body 105, and an actuator 115. In some embodiments, the applicator 100 further includes a battery 121.

In some embodiments, the battery 121 is a rechargeable battery, a capacitor, or the like. In some embodiments, the battery 121 is charged with a wired connection through the electrical port 107. The battery 121 may power the applicator 100.

In some embodiments, the cartridge further includes an interface 120 configured to couple to a removable cartridge 125. In some embodiments, the interface 120 houses a spring 140, a plug 123, and a pin 127. In some embodiments, the applicator 100 includes a removable cartridge 125. In some embodiments, the cartridge 125 houses a secondary spring 129. In some embodiments, the cartridge includes a microneedle plane 130. In some embodiments, the cartridge 125 contains the secondary spring and the pin 127. In some embodiments, the spring 140 and the secondary spring 129 work in tandem to remove and/or couple the cartridge 125 to the applicator 100, as shown and described in more detail in FIGS. 2A-2B. In some embodiments, the cartridge 125 is coupled with a microneedle plane 130 including one or more microneedles (as shown in FIG. 6) . In some embodiments, the plug 123 is configured to couple to the cartridge 125. In some embodiments, the spring 140 and the plug 123 together comprise a twist-push mechanism configured to couple and remove the cartridge 125 from the applicator 100. In operation, when the cartridge 125 is pushed towards the plug 123, the secondary spring 129 compresses. At the same time, the spring 140 compresses and allows the cartridge 125 to couple and/or interlock with the plug 123 to retain the cartridge 125 in the interface 120.

FIGA. 2A-2B are closeup views of an example applicator 100 with a removable cartridge 125, in accordance with the present technology. In some embodiments, the applicator 100 includes an interface 120 configured to couple with the cartridge 125. In some embodiments, the cartridge 125 is configured to couple with the interface 120 with a “twist lock mechanism” , which may comprise a spring (such as spring 140) and a plug (such as plug 123) . In operation, a user presses down on the cartridge 125 and twists the cartridge 125 to release it from the interface 120. In order to couple the cartridge 125 to the interface 120, the user may press the cartridge 125 into the interface 120 and twist the cartridge 125. In such embodiments, the cartridge 125 interlocks with the plug (such as plug 123) , which retains the cartridge 125.

FIG. 3 is a close-up view of an example applicator 100 with a cap 135, in accordance with the present technology. In some embodiments, the applicator 100 includes a cap 135. In some embodiments, the cap 135 is transparent or otherwise clear. In such embodiments, the cap 135 is configured to allow a user to see the microneedle plane 130 through the cap 135. In other embodiments, the cover 135 is opaque. In some embodiments, the cover 135 is cylindrical, but the cap 135 may take any shape or form factor. In some embodiments, the cap 135 is plastic, glass, metal, or the like. In some embodiments, the cover is configured to shield the one or more microneedles (as shown in FIG. 6) on the microneedle plane 130. This may prevent the one or more microneedles from being bent, damaged, and/or contaminated. In some embodiments, the cap keeps the microneedles of the microneedle plane 130 clean and sanitary. In some embodiments, the cap 135 is also replaceable. In operation, a user may remove the cap 135 from the cartridge 123 before applying microneedle therapy to their skin. In some embodiments, the cap 135 and/or the light source (such as light source 170) is configured to emit a light with an emission peak in the ultraviolet (UV) light range. In this manner, when the cap 135 is placed on the applicator 100, the UV light is emitted to sterilize the microneedle plane 130.

FIG. 4A is an internal cross-sectional view of an example applicator 100, in accordance with the present technology. In some embodiments, the applicator 100 includes a cartridge 125 with a microneedle plane 130. In some embodiments, the cartridge 125 houses a secondary spring 129 and a pin 127. In some embodiments, the cartridge 125 is removably coupled to an interface 120 of the applicator 100. In some embodiments, the interface 120 houses a spring 140 and a plug 123.

In some embodiments, the applicator 100 further includes a chip 145. In some embodiments, the chip 145 is configured to collect and/or transmit the one or more data of the cartridge 120 to an external device or smart device. In some embodiments, the applicator 100 further includes one or more sensors, as shown in FIG. 5. In some embodiments, each sensor in the sensor system is configured to transmit data to the chip 145. In some embodiments, the one or more sensors includes at least a humidity sensor, a pressure sensor, or an optical sensor. In some embodiments, the optical sensor is a camera.

FIG. 4B is the chip 145 of the example applicator 100 of FIG. 4A, in accordance with the present technology. In some embodiments, the chip 145 is a near field communication (NFC) tag. In some embodiments, the chip 145 is a microcontroller unit (MCU) tag. The chip 145 may communicate with an external device, such as a smart device (as shown in FIG. 7) . In some embodiments, the chip 145 transmits one or more data to the external device. In some embodiments, the one or more data may be used to create a treatment plan, monitor how the treatment is applied, direct a user to apply treatment, prevent treatment, and the like.

FIG. 5 is an example applicator 100 in use, in accordance with the present technology. In some embodiments, the cartridge 125 includes a sensor system. In some embodiments, the sensor system includes at least a pressure sensor 160, a humidity sensor 150, or a temperature sensor 155. In some embodiments, the sensor system includes a pressure sensor 160, a humidity sensor 150, a temperature sensor 155, or a combination thereof.

In operation, the user may move the cartridge 125 across the user’s skin S, as shown by the arrow. In some embodiments, the sensor system is configured to collect and monitor data, such as the pressure a user is applying to the cartridge, a temperature of the user’s skin, and/or a humidity of the user’s skin. In some embodiments, the humidity sensor 150 and the thermal sensor 155 (and/or thermal couple 165) measure the humidity of the skin and the temperature of the skin for loop control on the performance of microneedle therapy. For example, if the humidity sensor detects high humidity on the user’s skin and/or the temperature sensor detects a raised temperature of the user’s skin, the applicator 100 or an external device (such as smart device 200 in FIG. 7) can reduce an intensity of the microneedle therapy or even stop the microneedle therapy. In some embodiments, the combination of the humidity sensor 150 and the thermal sensor (and/or thermal couple 165) are used to measure a user’s transepidermal water loss (TEWL) .

In some embodiments, the applicator 100 (or a smart device, such as smart device 200) has a pressure threshold. In some embodiments, if the pressure measured by the pressure sensor 160 exceeds the pressure threshold, the applicator 100 or an external device, alerts the user to reduce pressure. In some embodiments, when the pressure exceeds the pressure threshold, the microneedle therapy is stopped. A chip (such as chip 145) can transmit the one or more data from the humidity sensor 150 and/or the temperature sensor 155 to the external device. In this manner, the applicator 100 can prevent a user from injuring themselves by applying microneedle therapy at an increased frequency and/or above the pressure threshold. The external device may use the one or more data in a variety of ways, as described herein.

FIG. 6 is an example microneedle plane 130, in accordance with the present technology. In some embodiments, the microneedle plane 130 includes a plurality of microneedles 175A, 175B, 175C…175N. In some embodiments, the plurality of microneedles 175A, 175B, 175C…175N is arranged in an array. In some embodiments, the plurality of microneedles 175A, 175B, 175C…175N are configured to penetrate up to a depth of 3 mm into the skin. In some embodiments, the plurality of microneedles 175A, 175B, 175C…175N are configured to penetrate up to a depth of 10 μm into the skin. In some embodiments, the plurality of microneedles 175A, 175B, 175C…175N are configured to exfoliate the skin but not penetrate it. As shown in FIG. 6, in some embodiments, the optical sensor 170 is disposed in a center of the microneedle plane 130.

In some embodiments, the microneedle plane 130 further includes a light source 170, such as a light emitting diode (LED) . In some embodiments, the LED 170 is configured to apply a light therapy. In some embodiments, LED 170 is configured to deliver blue light, redlight, infrared (IR) , and/or near infrared (NIR) light therapy as the cartridge 125 is moved across a user’s skin. In some embodiments, the light source 130 is configured to emit light having a peak emission is the visible spectrum, the NIR spectrum, the IR spectrum, the UV spectrum, or a combination thereof. In some embodiments, the light source 170 has a peak emission wavelength from 170 to 400 nm, 570-590 nm, 630 to 700 nm, 800 to 1200 nm, or a combination thereof.

FIG. 7 is an example method 700 of applying microneedle treatment and light treatment, in accordance with the present technology. In some embodiments, the method 700 is carried out by a cartridge (such as cartridge 125) and/or an applicator (such as applicator 100) . In some embodiments, the cartridge includes a microneedle plane (such as microneedle plane 130) including one or more microneedles (such as microneedles 175A, 175B, 175C…175N) . In some embodiments, the cartridge further includes an LED (such as LED 170) . In some embodiments, the cartridge and/or the applicator includes a chip (such as chip 145) configured to collect data from one or more sensors (such as humidity sensor 150, temperature sensor 155, thermal couple 165, and/or pressure sensor 160) .

In block 705, skin is contacted with the microneedle plane of the applicator. In some embodiments, a pressure sensor (which may be part of the sensor system) detects a pressure being applied to the skin. In some embodiments, the pressure data is transmitted to the chip of the applicator.

In block 710, the skin is prepared with one or more microneedles of the applicator. In some embodiments, the skin is penetrated at a depth not to exceed 5.0 mm. In some embodiments, penetrating the skin with the one or more microneedles is considered “microneedle therapy (or treatment) ” . In some embodiments, exfoliating but not penetrating the skin is considered “microneedle therapy (or treatment) ” .

In block 715, light therapy is applied with an LED on the cartridge. In some embodiments, the light treatment comprises a blue light treatment. In some embodiments, the light treatment comprises a red-light treatment. In some embodiments, the light treatment comprises a near infrared (NIR) light treatment. In some embodiments, block 710 and block 715 occur simultaneously.

In block 720, one or more data is measured with the sensor system (or one or more sensors) on the cartridge. In some embodiments, the one or more sensors include a temperature sensor, a pressure sensor, a humidity sensor, an optical sensor, and a combination thereof. In some embodiments, data from each sensor is collected by the chip.

It should be understood that method 700 should be interpreted as merely representative. In some embodiments, process blocks method 700 may be performed simultaneously, sequentially, in a different order, or even omitted, without departing from the scope of this disclosure.

The present application may reference quantities and numbers. Unless specifically stated, such quantities and numbers are not to be considered restrictive, but representative of the possible quantities or numbers associated with the present application. Also, in this regard, the present application may use the term "plurality" to reference a quantity or number. In this regard, the term "plurality" is meant to be any number that is more than one, for example, two, three, four, five, etc. The terms "about, " "approximately, " "near, " etc., mean plus or minus 5%of the stated value. For the purposes of the present disclosure, the phrase "at least one of A, B, and C, " for example, means (A) , (B) , (C) , (Aand B) , (A and C) , (B and C) , or (A, B, and C) , including all further possible permutations when greater than three elements are listed.

Embodiments disclosed herein may utilize circuitry in order to implement technologies and methodologies described herein, operatively connect two or more components, generate information, determine operation conditions, control an appliance, device, or method, and/or the like. Circuitry of any type can be used. In an embodiment, circuitry includes, among other things, one or more computing devices such as a processor (e.g., a microprocessor) , a central processing unit (CPU) , a digital signal processor (DSP) , an application-specific integrated circuit (ASIC) , a field-programmable gate array (FPGA) , or the like, or any combinations thereof, and can include discrete digital or analog circuit elements or electronics, or combinations thereof.

An embodiment includes one or more data stores that, for example, store instructions or data. Non-limiting examples of one or more data stores include volatile memory (e.g., Random Access memory (RAM) , Dynamic Random Access memory (DRAM) , or the like) , non-volatile memory (e.g., Read-Only memory (ROM) , Electrically Erasable Programmable Read-Only memory (EEPROM) , Compact Disc Read-Only memory (CD-ROM) , or the like) , persistent memory, or the like. Further non-limiting examples of one or more data stores include Erasable Programmable Read-Only memory (EPROM) , flash memory, or the like. The one or more data stores can be connected to, for example, one or more computing devices by one or more instructions, data, or power buses.

In an embodiment, circuitry includes a computer-readable media drive or memory slot configured to accept signal-bearing medium (e.g., computer-readable memory media, computer-readable recording media, or the like) . In an embodiment, a program for causing a system to execute any of the disclosed methods can be stored on, for example, a computer-readable recording medium (CRMM) , a signal-bearing medium, or the like. Non-limiting examples of signal-bearing media include a recordable type medium such as any form of flash memory, magnetic tape, floppy disk, a hard disk drive, a Compact Disc (CD) , a Digital Video Disk (DVD) , Blu-Ray Disc, a digital tape, a computer memory, or the like, as well as transmission type medium such as a digital and/or an analog communication medium (e.g., a fiber optic cable, a waveguide, a wired communications link, a wireless communication link (e.g., transmitter, receiver, transceiver, transmission logic, reception logic, etc. ) . Further non-limiting examples of signal-bearing media include, but are not limited to, DVD-ROM, DVD-RAM, DVD+RW, DVD-RW, DVD-R, DVD+R, CD-ROM, Super Audio CD, CD-R, CD+R, CD+RW, CD-RW, Video Compact Discs, Super Video Discs, flash memory, magnetic tape, magneto-optic disk, MINIDISC, non-volatile memory card, EEPROM, optical disk, optical storage, RAM, ROM, system memory, web server, or the like.

The detailed description set forth above in connection with the appended drawings, where like numerals reference like elements, are intended as a description of various embodiments of the present disclosure and are not intended to represent the only embodiments. Each embodiment described in this disclosure is provided merely as an example or illustration and should not be construed as preferred or advantageous over other embodiments. The illustrative examples provided herein are not intended to be exhaustive or to limit the disclosure to the precise forms disclosed. Similarly, any steps described herein may be interchangeable with other steps, or combinations of steps, in order to achieve the same or substantially similar result. Generally, the embodiments disclosed herein are non-limiting, and the inventors contemplate that other embodiments within the scope of this disclosure may include structures and functionalities from more than one specific embodiment shown in the figures and described in the specification.

In the foregoing description, specific details are set forth to provide a thorough understanding of exemplary embodiments of the present disclosure. It will be apparent to one skilled in the art, however, that the embodiments disclosed herein may be practiced without embodying all the specific details. In some instances, well-known process steps have not been described in detail in order not to unnecessarily obscure various aspects of the present disclosure. Further, it will be appreciated that embodiments of the present disclosure may employ any combination of features described herein.

The present application may include references to directions, such as "vertical, " "horizontal, " "front, " "rear, " "left, " "right, " "top, " and "bottom, " etc. These references, and other similar references in the present application, are intended to assist in helping describe and understand the particular embodiment (such as when the embodiment is positioned for use) and are not intended to limit the present disclosure to these directions or locations.

The present application may also reference quantities and numbers. Unless specifically stated, such quantities and numbers are not to be considered restrictive, but exemplary of the possible quantities or numbers associated with the present application. Also, in this regard, the present application may use the term "plurality" to reference a quantity or number. In this regard, the term "plurality" is meant to be any number that is more than one, for example, two, three, four, five, etc. The term "about, " "approximately, " etc., means plus or minus 5%of the stated value. The term "based upon" means "based at least partially upon. "

The principles, representative embodiments, and modes of operation of the present disclosure have been described in the foregoing description. However, aspects of the present disclosure, which are intended to be protected, are not to be construed as limited to the particular embodiments disclosed. Further, the embodiments described herein are to be regarded as illustrative rather than restrictive. It will be appreciated that variations and changes may be made by others, and equivalents employed, without departing from the spirit of the present disclosure. Accordingly, it is expressly intended that all such variations, changes, and equivalents fall within the spirit and scope of the present disclosure as claimed.

While illustrative embodiments have been illustrated and described, it will be appreciated that various changes can be made therein without departing from the spirit and scope of the invention.

Claims

A cartridge for treating skin, comprising:

a microneedle plane including one or more microneedles, configured to prepare the skin to provide a treatment;

a light source configured to apply a light treatment;

one or more sensors configured to measure one or more cartridge data; and

a chip configured to collect the one or more cartridge data.
The cartridge of Claim 1, wherein the chip is a near filed communication (NFC) tag.
The cartridge of Claim 1, wherein the chip is a microcontroller unit (MCU) tag.
The cartridge of any one of Claims 1-3, wherein the cartridge further comprises a cap configured to cover the one or more microneedles.
The cartridge of any one of Claims 1-4, wherein the one or more sensors is a humidity sensor, a pressure sensor, a temperature sensor, an optical sensor, or a combination thereof.
The cartridge of any one of Claims 1-5, wherein the one or more cartridge data is a change in humidity of the skin, a pressure level of the cartridge, a change in temperature of the skin, a change of color of the skin, or a combination thereof.
The cartridge of any one of Claims 1-6, wherein the one or more microneedles are arranged in an array on the microneedle plane.
The cartridge of any one of Claims 1-7, wherein the light source is disposed in a center of the microneedle plane.
The cartridge of any one of Claims 1-8, wherein the light source is configured to apply blue light, red light, or near infrared (NIR) light.
An applicator comprising:

a cartridge configured to removably couple to the applicator, comprising:

a microneedle plane including one or more microneedles, configured to prepare the skin to provide a microneedle treatment;

a light source configured to apply a light treatment;

one or more sensors configured to measure one or more cartridge data; and

a chip configured to collect the one or more cartridge data.
The applicator of Claim 10, wherein the applicator comprises a spring disposed inside an interface of the applicator; and

a plug configured to couple to the cartridge,

wherein the spring and the plug together comprise a twist-push mechanism configured to couple and remove the cartridge from the applicator.
The applicator of Claim 10 of Claim 11, wherein the applicator further comprises a cap configured to cover the one or more microneedles.
The applicator of any one of Claims 10-12, wherein the chip is a near filed communication (NFC) tag.
The applicator of any one of Claims 10-12, wherein the chip is a microcontroller unit (MCU) tag.
The applicator of any one of Claims 10-14, wherein the one or more sensors is a humidity sensor, a pressure sensor, a temperature sensor, an optical sensor, or a combination thereof.
A method of safely applying a microneedle treatment to skin, the method comprising:

contacting the skin with a microneedle plane of an applicator;

preparing the skin with one or more microneedles;

applying a light treatment with a light source; and

measuring one or more cartridge data with one or more sensors on the cartridge.
The method of Claim 16, wherein the method further comprises:

applying the light treatment simultaneously with the preparing of the skin.
The method of Claim 16 or Claim 17, wherein the light treatment comprises a blue light treatment.
The method of any one of Claims 16-18, wherein the light treatment comprises a red light treatment.
The method of any one of Claims 16-19, wherein the light treatment comprises a near infrared (NIR) light treatment.