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WO2025140050A1 - Calibration method and calibration system for calibrating scanning imaging device - Google Patents

Calibration method and calibration system for calibrating scanning imaging device Download PDF

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Publication number
WO2025140050A1
WO2025140050A1 PCT/CN2024/141121 CN2024141121W WO2025140050A1 WO 2025140050 A1 WO2025140050 A1 WO 2025140050A1 CN 2024141121 W CN2024141121 W CN 2024141121W WO 2025140050 A1 WO2025140050 A1 WO 2025140050A1
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WIPO (PCT)
Prior art keywords
parameters
energy spectrum
detector
calibration
ray source
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PCT/CN2024/141121
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French (fr)
Chinese (zh)
Inventor
陈志强
沈乐
张丽
邢宇翔
赵振华
孙运达
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Tsinghua University
Nuctech Co Ltd
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Tsinghua University
Nuctech Co Ltd
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Publication of WO2025140050A1 publication Critical patent/WO2025140050A1/en
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N23/00Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
    • G01N23/02Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by transmitting the radiation through the material
    • G01N23/04Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00 by transmitting the radiation through the material and forming images of the material

Definitions

  • the present disclosure relates to the field of scanning imaging technology, and more specifically, to a calibration method and a calibration system for calibrating a scanning imaging device.
  • Beer's law also known as the Beer-Lambert law, is a basic law that describes the absorption of light by matter. When a beam of parallel monochromatic light passes vertically through a uniform non-scattering absorbing substance, its absorbance is proportional to the concentration of the absorbing substance and the thickness of the absorbing layer.
  • the detector used for scanning imaging is required to have the same absorption energy spectrum, so that the ray attenuation passing through objects of the same thickness from different directions can be consistent.
  • the absorption energy spectrum of the detector is related to the thickness of the crystal into which the ray is incident. In the geometric arrangement of the single-target source probe centripetal, all rays are vertically incident on the crystal, the crystal thickness through which the ray passes is the same, and the absorption energy spectrum of the detector is the same.
  • the embodiments of the present disclosure provide a calibration method and a calibration system for calibrating a scanning imaging device.
  • a calibration method for calibrating a scanning imaging device wherein the scanning imaging device includes a radiation source for emitting radiation and a detector for receiving radiation. During the calibration process, a geometric calibration phantom or an energy spectrum calibration phantom is located in a scanning area formed by the radiation.
  • the calibration method includes:
  • a geometric calibration step is performed, wherein the geometric calibration step includes: collecting rays passing through the scanning area by the detector to obtain detector data related to the geometric calibration phantom; using the detector data, calibrating ray source parameters and detector parameters to obtain optimized ray source parameters and optimized detector parameters, and determining the optimized ray source parameters and optimized detector parameters as geometric calibration parameters, wherein the ray source parameters are used to represent the position of the ray source in the calibration system, and the detector parameters are used to represent the position of the detector in the calibration system;
  • the energy spectrum calibration phantom In a case where the energy spectrum calibration phantom is located in a scanning area formed by the radiation, determining the relative positions among the radiation source, the energy spectrum calibration phantom and the detector according to the geometric calibration parameters to obtain a geometric relationship among the radiation source, the energy spectrum calibration phantom and the detector;
  • the energy spectrum calibration step includes: collecting the rays passing through the scanning area through the detector to obtain actual projection data related to the energy spectrum phantom; using the actual projection data related to the energy spectrum phantom, according to the geometric relationship and the physical properties of the energy spectrum calibration phantom, calibrating the energy spectrum parameters to obtain optimized energy spectrum parameters, and determining the optimized energy spectrum parameters as energy spectrum calibration parameters.
  • a calibration method for calibrating a scanning imaging device comprising a radiation source for emitting radiation and a detector for receiving radiation.
  • the scanning imaging device comprises a radiation source for emitting radiation and a detector for receiving radiation.
  • both a geometric calibration phantom and an energy spectrum calibration phantom are located in a scanning area formed by the radiation.
  • the calibration method comprises:
  • a geometric calibration step and an energy spectrum calibration step are performed, wherein the performing of the geometric calibration step and the energy spectrum calibration step comprises:
  • the detector data is used to calibrate the energy spectrum parameters according to the geometric relationship and the physical properties of the energy spectrum calibration phantom to obtain optimized energy spectrum parameters, and the optimized energy spectrum parameters are determined as energy spectrum calibration parameters.
  • the detector data includes an actual projection position of the ray on the detector after the ray passes through a geometric calibration phantom in the scanning area;
  • the optimized energy spectrum parameters obtained for the last time during the first cycle are determined as energy spectrum calibration parameters.
  • the calibrating the energy spectrum parameters according to the theoretical projection data and the actual projection data to obtain optimized energy spectrum parameters includes: constructing an optimization function of the deviation between the theoretical projection data and the actual projection data with respect to the energy spectrum parameters; and calibrating the energy spectrum parameters according to the optimization function to obtain optimized energy spectrum parameters.
  • the geometric calibration phantom includes at least one metal wire; or, the geometric calibration phantom includes a plurality of metal wires, and the plurality of metal wires are distributed on the rotating table with different radii and/or different angles from each other.
  • the energy spectrum calibration phantom includes a plurality of parts respectively made of a plurality of materials, and at least one of the following properties of any two of the plurality of materials is different: density, atomic number.
  • the calibration system includes a rotating table, and at least one of the geometric calibration phantom and the energy spectrum calibration phantom is located on the rotating table; the detector collects the rays passing through the scanning area to obtain the detector data, including: controlling the ray source to emit rays; controlling the rotating table to rotate to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to rotate m times, wherein m is a positive integer greater than or equal to 1; and during the process of at least one of the geometric calibration phantom and the energy spectrum calibration phantom rotating m times, the detector collects the rays emitted from the ray source and passing through the scanning area.
  • the calibration system includes a lifting platform, and at least one of the geometric calibration phantom and the energy spectrum calibration phantom is located on the lifting platform; the detector collects the rays passing through the scanning area to obtain the detector data, including: controlling the ray source to emit rays; and controlling the lifting platform to rise and fall, so as to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to rise and fall.
  • the ray source includes N s target points, and the N s target points are spaced apart along a first direction, wherein N s is a positive integer greater than or equal to 2;
  • the collecting of rays passing through the scanning area by the detector to obtain detector data includes: controlling the N s target points to emit rays in a set order; and in the process of the N s target points emitting rays in the set order, the detector collecting rays emitted from the ray source and passing through the scanning area.
  • the method before determining the relative positions among the ray source, the energy spectrum calibration phantom and the detector, the method further comprises: calibrating the relative position of a calibration device body carrying the energy spectrum calibration phantom relative to the ray source and the detector.
  • the calibrating the energy spectrum parameters according to the geometric relationship and the physical properties of the energy spectrum calibration phantom to obtain optimized energy spectrum parameters, and determining the optimized energy spectrum parameters as energy spectrum calibration parameters specifically includes:
  • the loop process is executed until a preset condition is met, wherein the first loop process includes:
  • image reconstruction is performed on the geometric calibration phantom and the energy spectrum calibration phantom to obtain a first reconstructed image; segmentation is performed on the first reconstructed image to segment the geometric calibration phantom and the energy spectrum calibration phantom to obtain a second reconstructed image; and physical properties of the energy spectrum calibration phantom are obtained according to the second reconstructed image;
  • the optimized energy spectrum parameters obtained for the last time during the first cycle are determined as energy spectrum calibration parameters.
  • a calibration system for calibrating a scanning imaging device comprising: a calibration device body; at least one of a geometric calibration phantom and an energy spectrum calibration phantom disposed on the calibration device body; a driving member, the driving member being used to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to move; and a controller, the controller being configured to calibrate the scanning imaging device according to the calibration method as described above.
  • a calibration system for calibrating a scanning imaging device comprising: a base; a rotating table connected to the base; at least one of a geometric calibration phantom and an energy spectrum calibration phantom disposed on the rotating table, and at least one of the geometric calibration phantom and the energy spectrum calibration phantom is located on the rotating table; and a driving member, wherein the driving member is used to drive the rotating table to rotate so as to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to rotate, wherein the geometric calibration phantom comprises at least one metal wire; or, the geometric calibration phantom comprises a plurality of metal wires, and the plurality of metal wires are distributed on the rotating table with different radii and/or different angles from each other; and/or, the energy spectrum calibration phantom comprises a plurality of parts respectively composed of a plurality of materials, and at least one of the following properties of any two of the plurality of materials is different:
  • the calibration system further includes: a lifting platform, wherein the lifting platform is connected to the base, and the rotating platform is disposed on the lifting platform.
  • FIG1 schematically shows a schematic diagram of the projection relationship between a ray source, a scanned object and a detector.
  • FIG. 3B is a schematic structural diagram of a scanning stage included in a static CT device according to other exemplary embodiments of the present disclosure.
  • FIG. 4B is a schematic structural diagram of a calibration system according to some exemplary embodiments of the present disclosure, viewed from another angle.
  • FIG. 4C is a schematic diagram of the structure of a calibration system according to some exemplary embodiments of the present disclosure, which schematically shows a metal wire.
  • FIG. 4D is a side view of the calibration system shown in FIG. 4C .
  • FIG. 4E is a schematic diagram of the structure of a calibration system according to some exemplary embodiments of the present disclosure, which schematically shows a plurality of metal wires.
  • FIG. 4F is a projection diagram of the four metal wires shown in FIG. 4E on the rotating stage.
  • FIG. 5 is a flow chart of a calibration method according to some exemplary embodiments of the present disclosure.
  • FIG. 6 is a flowchart of a calibration method according to some other exemplary embodiments of the present disclosure.
  • FIG. 7 is a flowchart of a geometric calibration step in a calibration method according to some exemplary embodiments of the present disclosure.
  • each distributed ray source 20 has one or more targets, the energy of the targets can be set, and the order of target activation can be set.
  • the targets can be distributed on multiple scanning planes (for example, the scanning plane is perpendicular to the direction of passage). In each plane, the target distribution can be one or more continuous or discontinuous straight lines or arcs. Since the target energy can be set, a variety of scanning methods can be achieved during the beam emission process, such as different targets having different energy spectra, or targets located in different planes having different energies.
  • the targets can be designed in groups, such as the targets of each module as a group, or the targets of each plane as a group.
  • the order of electronic targeting of the targets in the same group is adjustable, and sequential beam emission and alternating beam emission can be achieved. Targets in different groups can be activated at the same time for scanning to speed up the scanning speed.
  • the detector 30 may be a single row or multiple rows, and the detector type may be a single energy, dual energy or energy spectrum detector.
  • Static CT has gradually become a research hotspot in the field of CT due to its advantages such as high scanning speed, high stability and flexible scanning methods.
  • it has different requirements from the original spiral CT in many data processing methods. For example, due to the geometric correction caused by multiple targets, the spiral CT processing method cannot be used.
  • CT imaging theory if you want to accurately reconstruct the scanned object, you must know the precise position of the radiation source target and the detector crystal. Since there are errors in mechanical manufacturing and installation, geometric calibration becomes an essential step in CT imaging. For static CT using distributed radiation sources or multiple single-target radiation sources, the radiation sources themselves are larger in size or more in number, so the manufacturing and installation errors will be correspondingly larger, which will have a greater impact on the imaging quality. Similarly, the detector will have the same problem, and the geometric error also needs to be corrected through geometric correction.
  • CT imaging theory is based on the fact that ray attenuation conforms to Beer's law, which requires that the detectors used for scanning imaging have the same absorption energy spectrum, so that the attenuation of rays passing through objects of the same thickness from different directions can be consistent.
  • the inventors have found through research that the absorption energy spectrum of the detector is related to the thickness of the crystal into which the rays are incident. In the geometric arrangement of a single target source probe centripetal, all rays are vertically incident on the crystal, the crystal thickness through which the rays pass is the same, and the absorption energy spectrum of the detector is the same.
  • the embodiments of the present disclosure provide a calibration method and a calibration system for calibrating a scanning imaging device, which can perform geometric calibration and energy spectrum calibration on the scanning imaging device, for example, can perform geometric calibration and energy spectrum calibration on a static CT device based on a distributed ray source.
  • FIG. 4A is a schematic diagram of the structure of a calibration system according to some exemplary embodiments of the present disclosure.
  • FIG. 4B is a schematic diagram of the structure of a calibration system according to some exemplary embodiments of the present disclosure observed from another angle.
  • FIG. 4C is a schematic diagram of the structure of a calibration system according to some exemplary embodiments of the present disclosure, schematically showing a metal wire.
  • FIG. 4D is a side view of the calibration system shown in FIG. 4C.
  • FIG. 4E is a schematic diagram of the structure of a calibration system according to some exemplary embodiments of the present disclosure, schematically showing multiple metal wires.
  • both the geometric calibration phantom 50 and the energy spectrum calibration phantom 60 are disposed on the rotating table 420.
  • one of the geometric calibration phantom 50 and the energy spectrum calibration phantom 60 may be disposed on the rotating table 420.
  • only the geometric calibration phantom 50 is disposed on the rotating table 420.
  • the rotating table 420 rotates around the rotation axis AX1.
  • a metal wire is vertically arranged on the rotating table 420 and is offset from the rotation axis AX1. Due to the centrifugal arrangement of the geometric calibration phantom on the rotating table 420, the geometric calibration phantom can be in different geometric positions during the rotation of the rotating table 420, which is conducive to obtaining calibration data from multiple different geometric positions, thereby improving the accuracy of calibration.
  • the geometric calibration phantom 50 may include a plurality of metal wires, which are respectively located at different centrifugal positions of the rotating stage 420, that is, the plurality of metal wires are distributed on the rotating stage 420 at different radii and/or different angles. That is, on the rotating stage 420, at least one of the radius and angle of any one of the plurality of metal wires is different from at least one of the radius and angle of another of the plurality of metal wires.
  • first metal wire 501 a first metal wire 501
  • second metal wire 502 a third metal wire 503, and a fourth metal wire 504.
  • the first metal wire 501, the second metal wire 502, the third metal wire 503, and the fourth metal wire 504 are all vertically arranged on the rotating stage 420, and the offset distances from the rotating axis AX1 are ⁇ 1 , ⁇ 2 , ⁇ 3 , ⁇ 4 , respectively.
  • FIG4F is a projection diagram of the four metal wires shown in FIG4E on the rotating table.
  • a polar coordinate system is established, in which the point of the orthographic projection of the rotation axis AX1 on the rotating table 420 is taken as the pole AXO, and a ray OX starting from the pole AXO is taken as the polar axis.
  • the positions of the four metal wires can be represented by ( ⁇ , ⁇ ), wherein ⁇ corresponds to the polar diameter, vector radius or radius in the polar coordinate system, specifically the distance of the point of the orthographic projection of the metal wire on the rotating table relative to the pole AXO; ⁇ corresponds to the polar angle or radian in the polar coordinate system, specifically the angle of the line connecting the point of the orthographic projection of the metal wire on the rotating table and the pole relative to the polar axis OX.
  • the positions of the first metal wire 501, the second metal wire 502, the third metal wire 503 and the fourth metal wire 504 are respectively expressed as ( ⁇ 1 , ⁇ 1 ), ( ⁇ 2 , ⁇ 2 ), ( ⁇ 3 , ⁇ 3 ), ( ⁇ 4 , ⁇ 4 ). Any two of ⁇ 1 , ⁇ 2 , ⁇ 3 , ⁇ 4 are not equal, and/or any two of ⁇ 1 , ⁇ 2 , ⁇ 3 , ⁇ 4 are not equal.
  • multiple metal wires are arranged on the rotating table 420 and have different offset distances or offset angles from the rotation axis AX1. In this way, during the rotation of the rotating table 420, the multiple metal wires can be in different geometric positions, which is conducive to obtaining calibration data from multiple different geometric positions, thereby further improving the calibration accuracy.
  • the diameter of the metal wire is no greater than the width of a single detector crystal.
  • the energy spectrum calibration phantom 60 is located at the center of the rotating stage 420.
  • the geometric center of the energy spectrum calibration phantom 60 is located on the rotation axis AX1 of the rotating stage 420.
  • the energy spectrum calibration phantom 60 may include a plurality of parts respectively made of a plurality of materials, and at least one of the following properties of any two of the plurality of materials is different: density, atomic number.
  • the energy spectrum calibration model 60 can be an object with a certain shape composed of a known material or an unknown material with sufficient attenuation capability.
  • the material of the energy spectrum calibration model 60 can be selected from graphite, organic glass, polyethylene, polyoxymethylene, aluminum (alloy), magnesium (alloy), silicon dioxide, polyvinyl chloride, titanium (alloy), iron, copper, etc.
  • the chemical composition and physical density and other properties of these materials are known information.
  • the material of the energy spectrum calibration model 60 can also be selected from some materials with stable physical and chemical properties, but the composition ratio information of the material cannot be accurately obtained.
  • the atomic number range of the material of the energy spectrum calibration phantom 60 should cover a wider range as possible.
  • the shape of the energy spectrum calibration phantom 60 can be a cylinder, a prism, a pyramid, or an irregular shape. During the calibration process, the length of the intersection line between the ray and the energy spectrum calibration phantom 60 should cover a wide range as much as possible.
  • the shape of the energy spectrum calibration phantom 60 is a rectangular parallelepiped, but this shape is only exemplary and is not a limitation to the embodiments of the present disclosure. In other embodiments of the present disclosure, the energy spectrum calibration phantom 60 may adopt any other suitable shape.
  • the calibration system 40 may further include a lifting platform 440, the lifting platform 440 is connected to the base 410, and the rotating platform 420 is disposed on the lifting platform 440.
  • the metal wire can be scanned at multiple height positions to obtain more calibration data by controlling the lifting platform to translate up and down a fixed distance, thereby facilitating improving the calibration accuracy.
  • the base 410 is used to carry other components and maintain the stability of the components arranged thereon.
  • the driving member 430 may include a moving driving mechanism for driving the lifting platform 440 to move up and down; and/or a rotating driving mechanism for driving the rotating platform 420 to rotate.
  • the rotation drive mechanism for driving the rotating table 420 to rotate may include at least one of a gear transmission mechanism, a servo motor drive mechanism and a stepper motor drive mechanism.
  • the gear transmission mechanism may include a driving motor, a driving gear and a driven gear, and the rotational force transmission is realized by the meshing of the gears.
  • the servo motor drive is to realize the rotation of the rotating table by controlling the speed and position of the servo motor.
  • the servo motor is usually used in combination with an encoder and a closed-loop control system to achieve high-precision rotation control.
  • the stepper motor drive realizes the rotation of the rotating table by controlling the pulse signal of the stepper motor.
  • the stepper motor has a discrete step angle, which can accurately control the position and speed of the rotating table.
  • obtaining the initial detector data p i may include: controlling the ray source 20 to emit rays; and controlling the lifting platform 440 to move up and down, so as to drive the geometric calibration phantom 50 to move up and down.
  • the detector data prj i obtained in sub-step S710 includes the actual projection position, that is, the actual projection position of the geometric calibration phantom 50 (such as a metal wire) can be extracted from the detector data prj i , which can be described as pos(s i , P d ). It can be understood that the actual projection position is a function of the ray source parameters and the detector parameters.
  • the theoretical projection position of the geometric calibration phantom 50 corresponding to the projection data prj i can be obtained through geometric calculation, which is recorded as cpos( si , Pd ). It can be understood that the theoretical projection position cpos( si , Pd ) is also a function of the ray source parameter and the detector parameter.
  • sub-step S740 the ray source parameters and the detector parameters are calibrated according to the actual projection position and the theoretical projection position to obtain optimized ray source parameters and optimized detector parameters.
  • the optimized ray source parameters and the optimized detector parameters are determined as geometric calibration parameters.
  • FIG8A is an exemplary flowchart of obtaining optimized ray source parameters and optimized detector parameters in a geometric calibration step in a calibration method according to some exemplary embodiments of the present disclosure.
  • sub-step S740 may include sub-steps S741 - S742 .
  • sub-step S741 an optimization function of the deviation between the actual projection position and the theoretical projection position with respect to the ray source parameters and the detector parameters is constructed, in which the deviation is the dependent variable, and the ray source parameters and the detector parameters are the independent variables.
  • the ray source parameters and detector parameters corresponding to when the deviation takes the minimum value are determined as optimized ray source parameters and optimized detector parameters.
  • the optimized ray source parameters and the optimized detector parameters can be obtained by solving the following optimization function:
  • argmin is a mathematical term used to represent the parameter value (the value of the independent variable) of a function to achieve the minimum value in its domain. Specifically, in this optimization function, it means: The ray source parameter si and detector parameter Pd when the minimum value is obtained; si is the ray source parameter; Pd is the detector parameter; Ns is the total number of targets in the distributed ray source; i represents the number of a target in the distributed ray source, 1 ⁇ i ⁇ Ns ; pos( si , Pd ) represents the actual projection position; cpos( si , Pd ) represents the theoretical projection position.
  • FIG8B is an exemplary flowchart of obtaining optimized ray source parameters and optimized detector parameters in a geometric calibration step in a calibration method according to other exemplary embodiments of the present disclosure.
  • an optimization function is constructed, which includes a projection position constraint term and a target distance constraint term, wherein the projection position constraint term is a first function of the deviation between the actual projection position and the theoretical projection position with respect to the ray source parameters and the detector parameters; the target distance constraint term is a second function of the deviation between the actual distance and the theoretical distance between two adjacent target points with respect to the ray source parameters and the detector parameters.
  • the projection position constraint item has a first weight value
  • the target distance constraint item has a second weight value.
  • the second weight value may be 0.
  • the corresponding ray source parameters and detector parameters when the weighted sum of the deviation between the actual projection position and the theoretical projection position and the deviation between the actual distance between two adjacent target points and the theoretical distance takes the minimum value are determined as the optimized ray source parameters and the optimized detector parameters.
  • some constraints are added to the optimization objective function according to the actual situation to make the solution of the optimization problem more stable. For example, although there is an error in the position of the target point, the deviation between the target points is within a certain range, and the following target point distance constraint term can be added to the optimization function, where dis(s i , s i+1 ) represents the distance between target points i and i+1, d s represents the theoretical distance between the two target points, and ⁇ 1 and ⁇ 2 represent the weights of the two constraints.
  • the optimized ray source parameters and the optimized detector parameters can be obtained by solving the following optimization function:
  • argmin is a mathematical term used to represent the parameter value (the value of the independent variable) of a function to achieve the minimum value in its domain. Specifically, in this optimization function, it means: The ray source parameter si and detector parameter Pd when the minimum value is obtained; si is the ray source parameter; Pd is the detector parameter; Ns is the total number of targets in the distributed ray source; i represents the number of a target in the distributed ray source; pos( si , Pd ) represents the actual projection position; cpos( si , Pd ) represents the theoretical projection position; dis( si , si +1 ) represents the distance between targets i and i+1; ds represents the theoretical spacing between two targets; ⁇ 1 and ⁇ 2 represent the weight values of the two constraints.
  • the projection position constraint is the target distance constraint item.
  • the weight value of the projection position constraint item is ⁇ 1
  • the weight value of the target distance constraint item is ⁇ 2 .
  • the weight value ⁇ 1 of the projection position constraint item is greater than the weight value ⁇ 2 of the target distance constraint item, so that when performing calibration, the influencing factors of the projection position constraint are more considered.
  • the calibration system 40 is placed on a conveying device (e.g., the conveying mechanism 110 shown in FIG. 2 ) of the scanning imaging device, and the conveying device is controlled to transport the energy spectrum calibration phantom 60 of the calibration system 40 to the scanning plane of the X-ray, so that the energy spectrum calibration phantom 60 is in the scanning plane formed by the ray source 20 and the detector 30.
  • a conveying device e.g., the conveying mechanism 110 shown in FIG. 2
  • the conveying device is controlled to transport the energy spectrum calibration phantom 60 of the calibration system 40 to the scanning plane of the X-ray, so that the energy spectrum calibration phantom 60 is in the scanning plane formed by the ray source 20 and the detector 30.
  • the conveying device is controlled to transport the energy spectrum calibration phantom 60 of the calibration system 40 to the scanning plane of the X-ray, so that the energy spectrum calibration phantom 60 is in the scanning plane formed by the ray source 20 and the detector 30.
  • FIG9 is a flow chart of the energy spectrum calibration step in the calibration method according to some exemplary embodiments of the present disclosure.
  • the calibration method can be used to perform energy spectrum calibration on a scanning imaging device.
  • the calibration method can perform energy spectrum calibration on a static CT device.
  • the ray source 20 can be a distributed ray source, which includes N s target points 210, and the N s target points are spaced and distributed along a first direction, wherein N s is a positive integer greater than or equal to 2.
  • the first direction can correspond to the straight line arrangement direction shown in FIG3A or the arc arrangement method shown in FIG3B. It should be noted that in the embodiments of the present disclosure, no special restrictions are imposed on the arrangement direction and form of the multiple target points of the distributed ray source.
  • the energy spectrum calibration step in the calibration method may include sub-steps S910 to S960.
  • sub-step S910 when the energy spectrum calibration phantom is located in the scanning area formed by the rays, the geometric relationship between the ray source, the energy spectrum calibration phantom and the detector is acquired according to the relative positions between the ray source, the energy spectrum calibration phantom and the detector.
  • the detector collects rays passing through the scanning area to obtain actual projection data.
  • sub-step S930 the physical properties of the energy spectrum calibration phantom are obtained, wherein the physical properties are predetermined according to the constituent materials of the energy spectrum calibration phantom.
  • sub-step S940 based on the physical properties of the energy spectrum calibration phantom and the geometric relationship, theoretical projection data are calculated using a predetermined plurality of basic energy spectra.
  • the energy spectrum parameters are calibrated according to the theoretical projection data and the actual projection data to obtain optimized energy spectrum parameters.
  • the optimized energy spectrum parameters are determined as energy spectrum calibration parameters.
  • the energy spectrum calibration model 60 can be an object with a certain shape and composed of a known material with sufficient attenuation capability.
  • the material of the energy spectrum calibration model 60 can be selected from graphite, organic glass, polyethylene, polyoxymethylene, aluminum (alloy), magnesium (alloy), silicon dioxide, polyvinyl chloride, titanium (alloy), iron, copper, etc. The chemical composition and physical density of these materials are known information.
  • the physical properties of the energy spectrum calibration phantom 60 can be predetermined, the physical properties of the energy spectrum calibration phantom 60 obtained in sub-step S930 are accurate. Accordingly, in sub-step S940, accurate theoretical projection data can be calculated based on the accurate physical properties and geometric relationship of the energy spectrum calibration phantom 60.
  • the optimized energy spectrum parameters obtained in sub-step S950 can be used as the final energy spectrum calibration parameters without iteration.
  • Fig. 10 is a flow chart of an energy spectrum calibration step in a calibration method according to some other exemplary embodiments of the present disclosure.
  • the energy spectrum calibration step in the calibration method may include sub-steps S1010 to S1060.
  • sub-step S1010 when the energy spectrum calibration phantom is located in the scanning area formed by the rays, the geometric relationship between the ray source, the energy spectrum calibration phantom and the detector is acquired according to the relative positions between the ray source, the energy spectrum calibration phantom and the detector.
  • the detector collects rays passing through the scanning area to obtain actual projection data.
  • sub-step S1030 a loop process is executed until a preset condition is met, and the first loop process includes sub-steps S1031 to S1034.
  • sub-step S1031 image reconstruction is performed on the energy spectrum calibration phantom according to the energy spectrum information, and physical properties of the energy spectrum calibration phantom are obtained according to the result of the image reconstruction.
  • sub-step S1032 based on the physical properties of the energy spectrum calibration phantom and the geometric relationship, theoretical projection data are calculated using a predetermined plurality of basic energy spectra.
  • the energy spectrum parameters are calibrated according to the theoretical projection data and the actual projection data to obtain optimized energy spectrum parameters.
  • sub-step S1034 energy spectrum information is acquired based on the optimized energy spectrum parameters.
  • the optimized energy spectrum parameters obtained last time during the first cycle are determined as energy spectrum calibration parameters.
  • a drive 1010 is also connected to the I/O interface 1005 as needed.
  • a removable medium 1011 such as a magnetic disk, an optical disk, a magneto-optical disk, a semiconductor memory, etc., is installed on the drive 1010 as needed, so that a computer program read therefrom is installed into the storage portion 1008 as needed.
  • the present disclosure also provides a computer-readable storage medium, which may be included in the device/apparatus/system described in the above embodiments; or may exist independently without being assembled into the device/apparatus/system.
  • the above computer-readable storage medium carries one or more programs, and when the above one or more programs are executed, the method according to the embodiment of the present disclosure is implemented.
  • each box in the flow chart or block diagram can represent a module, a program segment, or a part of a code, and the above-mentioned module, program segment, or a part of a code contains one or more executable instructions for realizing the specified logical function.
  • the functions marked in the box can also occur in a different order from the order marked in the accompanying drawings. For example, two boxes represented in succession can actually be executed substantially in parallel, and they can sometimes be executed in the opposite order, depending on the functions involved.
  • each box in the block diagram or flow chart, and the combination of the boxes in the block diagram or flow chart can be implemented with a dedicated hardware-based system that performs a specified function or operation, or can be implemented with a combination of dedicated hardware and computer instructions.

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Abstract

Provided is a calibration method for calibrating a scanning imaging device, comprising: when a geometric calibration phantom is located in a scanning area formed by rays, executing a geometric calibration step, which comprises: collecting rays that pass through the scanning area by means of a detector to obtain detector data; performing calibration on a ray source parameter and a detector parameter by utilizing the detector data, so as to obtain an optimized ray source parameter and an optimized detector parameter, and determining the optimized ray source parameter and the optimized detector parameter as geometric calibration parameters; and when an energy spectrum calibration phantom is located in a scanning area formed by rays, executing an energy spectrum calibration step, which comprises: collecting rays that pass through the scanning area by means of the detector, and obtaining real projection data related to the energy spectrum phantom; and performing calibration on an energy spectrum parameter according to a geometric relationship and a physical attribute of the energy spectrum calibration phantom by utilizing the actual projection data, so as to obtain an optimized energy spectrum parameter, and determining the optimized energy spectrum parameter as an energy spectrum calibration parameter.

Description

用于标定扫描成像设备的标定方法和系统Calibration method and system for calibrating scanning imaging equipment

本申请要求于2023年12月29日递交的中国专利申请No.202311864101.9的优先权,其内容一并在此作为参考。This application claims priority to Chinese Patent Application No. 202311864101.9 filed on December 29, 2023, the contents of which are incorporated herein by reference.

技术领域Technical Field

本公开涉及扫描成像技术领域,更具体地,涉及一种用于标定扫描成像设备的标定方法和标定系统。The present disclosure relates to the field of scanning imaging technology, and more specifically, to a calibration method and a calibration system for calibrating a scanning imaging device.

背景技术Background Art

根据扫描成像理论,根据扫描成像理论,如果要对被扫描对象精确图像重建,必须已知射线源靶点和探测器晶体的精确位置,由于机械制作和安装存在误差,因此几何标定成为扫描成像中必不可少的步骤。另外,当射线从射线源发出时,经过被扫描对象之后入射到探测器上,在此过程中,射线的衰减符合Beer定律。Beer定律,也被称为比尔-朗伯定律,是描述物质对光吸收的基本定律。当一束平行单色光垂直通过某一均匀非散射的吸光物质时,其吸光度与吸光物质的浓度及吸收层厚度成正比。According to scanning imaging theory, if you want to accurately reconstruct the image of the scanned object, you must know the precise position of the ray source target and the detector crystal. Due to errors in mechanical manufacturing and installation, geometric calibration becomes an indispensable step in scanning imaging. In addition, when the ray is emitted from the ray source, it passes through the scanned object and then incidents on the detector. During this process, the attenuation of the ray conforms to Beer's law. Beer's law, also known as the Beer-Lambert law, is a basic law that describes the absorption of light by matter. When a beam of parallel monochromatic light passes vertically through a uniform non-scattering absorbing substance, its absorbance is proportional to the concentration of the absorbing substance and the thickness of the absorbing layer.

例如,以静态CT扫描成像技术为例,根据CT成像理论,如果要对被扫描对象精确CT重建,必须已知射线源靶点和探测器晶体的精确位置,由于机械制作和安装存在误差,因此几何标定成为CT成像中必不可少的步骤。采用分布式射线源或多个单靶点射线源的静态CT,由于射线源本身尺寸较大或数量较多,制作和安装误差也会相应的更大,对成像质量产生较大影响。类似的,探测器也会存在相同的问题,也需要通过几何校正修正几何误差。以CT扫描成像技术为例,根据CT成像理论,基于射线衰减符合Beer定律,要求用于扫描成像的探测器具备相同的吸收能谱,这样从不同方向穿过相同厚度的对象射线衰减才可以一致。探测器的吸收能谱和射线入射的晶体厚度相关。在单靶点源探向心的几何排布中,所有射线均为垂直入射晶体,射线穿过的晶体厚度相同,探测器的吸收能谱相同。但是,在静态CT扫描成像设备中,由于单个晶体需要接收不同靶点发出的射线,因此不同靶点射线的入射角度不同,穿过的晶体厚度不同,从而导致吸收能谱不同。而且,不同靶点的能谱也可能存在差异。能谱不一致导致的数据不一致性也是影响重建数值准确性的重要因素。For example, taking static CT scanning imaging technology as an example, according to CT imaging theory, if the scanned object is to be accurately reconstructed by CT, the precise position of the ray source target and the detector crystal must be known. Due to the errors in mechanical manufacturing and installation, geometric calibration becomes an indispensable step in CT imaging. For static CT using distributed ray sources or multiple single-target ray sources, the manufacturing and installation errors will be correspondingly larger due to the large size or large number of ray sources themselves, which will have a greater impact on the imaging quality. Similarly, the detector will also have the same problem, and the geometric error needs to be corrected through geometric correction. Taking CT scanning imaging technology as an example, according to CT imaging theory, based on the fact that ray attenuation conforms to Beer's law, the detector used for scanning imaging is required to have the same absorption energy spectrum, so that the ray attenuation passing through objects of the same thickness from different directions can be consistent. The absorption energy spectrum of the detector is related to the thickness of the crystal into which the ray is incident. In the geometric arrangement of the single-target source probe centripetal, all rays are vertically incident on the crystal, the crystal thickness through which the ray passes is the same, and the absorption energy spectrum of the detector is the same. However, in static CT scanning imaging equipment, since a single crystal needs to receive rays from different targets, the rays from different targets have different incident angles and pass through different crystal thicknesses, resulting in different absorption energy spectra. Moreover, the energy spectra of different targets may also be different. Data inconsistency caused by inconsistent energy spectra is also an important factor affecting the accuracy of reconstruction values.

在本部分中公开的以上信息仅用于对本公开的技术构思的背景的理解,因此,以上信息可包含不构成相关技术的信息。The above information disclosed in this section is only for understanding of the background of the technical concept of the present disclosure and therefore, the above information may contain information that does not constitute the relevant technology.

发明内容Summary of the invention

本公开实施例提出一种用于标定扫描成像设备的标定方法和标定系统。The embodiments of the present disclosure provide a calibration method and a calibration system for calibrating a scanning imaging device.

在一个方面,提供一种用于标定扫描成像设备的标定方法,所述扫描成像设备包括用于发出射线的射线源和用于接收射线的探测器,在标定过程中,几何标定模体或能谱标定模体位于所述射线形成的扫描区域中,所述标定方法包括:In one aspect, a calibration method for calibrating a scanning imaging device is provided, wherein the scanning imaging device includes a radiation source for emitting radiation and a detector for receiving radiation. During the calibration process, a geometric calibration phantom or an energy spectrum calibration phantom is located in a scanning area formed by the radiation. The calibration method includes:

在几何标定模体位于所述射线形成的扫描区域中的情况下,执行几何标定步骤,其中,所述几何标定步骤包括:通过所述探测器采集经过所述扫描区域的射线,获得与所述几何标定模体相关的探测器数据;利用所述探测器数据,对射线源参数和探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,并将所述优化的射线源参数和优化的探测器参数确定为几何标定参数,其中,所述射线源参数用于表示所述射线源在标定系统中的位置,所述探测器参数用于表示所述探测器在所述标定系统中的位置;In the case where the geometric calibration phantom is located in the scanning area formed by the rays, a geometric calibration step is performed, wherein the geometric calibration step includes: collecting rays passing through the scanning area by the detector to obtain detector data related to the geometric calibration phantom; using the detector data, calibrating ray source parameters and detector parameters to obtain optimized ray source parameters and optimized detector parameters, and determining the optimized ray source parameters and optimized detector parameters as geometric calibration parameters, wherein the ray source parameters are used to represent the position of the ray source in the calibration system, and the detector parameters are used to represent the position of the detector in the calibration system;

在能谱标定模体位于所述射线形成的扫描区域中的情况下,根据所述几何标定参数,确定所述射线源、所述能谱标定模体和所述探测器之间的相对位置,以获取所述射线源、所述能谱标定模体和所述探测器之间的几何关系;以及In a case where the energy spectrum calibration phantom is located in a scanning area formed by the radiation, determining the relative positions among the radiation source, the energy spectrum calibration phantom and the detector according to the geometric calibration parameters to obtain a geometric relationship among the radiation source, the energy spectrum calibration phantom and the detector; and

在能谱标定模体位于所述射线形成的扫描区域中的情况下,执行能谱标定步骤,其中,所述能谱标定步骤包括:通过所述探测器采集经过所述扫描区域的射线,获取与所述能谱模体相关的实际投影数据;利用与所述能谱模体相关的实际投影数据,根据所述几何关系和所述能谱标定模体的物理属性,对能谱参数进行标定,以获取优化的能谱参数,并将所述优化的能谱参数确定为能谱标定参数。When the energy spectrum calibration phantom is located in the scanning area formed by the rays, the energy spectrum calibration step is performed, wherein the energy spectrum calibration step includes: collecting the rays passing through the scanning area through the detector to obtain actual projection data related to the energy spectrum phantom; using the actual projection data related to the energy spectrum phantom, according to the geometric relationship and the physical properties of the energy spectrum calibration phantom, calibrating the energy spectrum parameters to obtain optimized energy spectrum parameters, and determining the optimized energy spectrum parameters as energy spectrum calibration parameters.

在另一方面,提供一种用于标定扫描成像设备的标定方法,所述扫描成像设备包括用于发出射线的射线源和用于接收射线的探测器,在标定过程中,几何标定模体和能谱标定模体两者均位于所述射线形成的扫描区域中,所述标定方法包括:In another aspect, a calibration method for calibrating a scanning imaging device is provided, wherein the scanning imaging device comprises a radiation source for emitting radiation and a detector for receiving radiation. During the calibration process, both a geometric calibration phantom and an energy spectrum calibration phantom are located in a scanning area formed by the radiation. The calibration method comprises:

在几何标定模体和能谱标定模体两者均位于所述射线形成的扫描区域中的情况下,执行几何标定步骤和能谱标定步骤,其中,所述执行几何标定步骤和能谱标定步骤包括:In the case where both the geometric calibration phantom and the energy spectrum calibration phantom are located in the scanning area formed by the rays, a geometric calibration step and an energy spectrum calibration step are performed, wherein the performing of the geometric calibration step and the energy spectrum calibration step comprises:

通过所述探测器采集经过所述扫描区域的射线,获取与所述几何标定模体和所述能谱标定模体均相关的探测器数据;Collecting rays passing through the scanning area by the detector to obtain detector data related to both the geometric calibration phantom and the energy spectrum calibration phantom;

利用所述探测器数据,对射线源参数和探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,并将所述优化的射线源参数和优化的探测器参数确定为几何标定参数,其中,所述射线源参数用于表示所述射线源在标定系统中的位置,所述探测器参数用于表示所述探测器在所述标定系统中的位置;Calibrate the ray source parameters and the detector parameters by using the detector data to obtain optimized ray source parameters and optimized detector parameters, and determine the optimized ray source parameters and optimized detector parameters as geometric calibration parameters, wherein the ray source parameters are used to represent the position of the ray source in the calibration system, and the detector parameters are used to represent the position of the detector in the calibration system;

根据所述几何标定参数,确定所述射线源、所述能谱标定模体和所述探测器之间的相对位置,以获取所述射线源、所述能谱标定模体和所述探测器之间的几何关系;以及Determining the relative positions of the ray source, the energy spectrum calibration phantom, and the detector according to the geometric calibration parameters to obtain a geometric relationship between the ray source, the energy spectrum calibration phantom, and the detector; and

利用所述探测器数据,根据所述几何关系和所述能谱标定模体的物理属性,对能谱参数进行标定,以获取优化的能谱参数,并将所述优化的能谱参数确定为能谱标定参数。The detector data is used to calibrate the energy spectrum parameters according to the geometric relationship and the physical properties of the energy spectrum calibration phantom to obtain optimized energy spectrum parameters, and the optimized energy spectrum parameters are determined as energy spectrum calibration parameters.

根据一些示例性的实施例,所述探测器数据包括所述射线经过所述扫描区域中的几何标定模体后在所述探测器上的实际投影位置;According to some exemplary embodiments, the detector data includes an actual projection position of the ray on the detector after the ray passes through a geometric calibration phantom in the scanning area;

所述对射线源参数和探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,并将所述优化的射线源参数和优化的探测器参数确定为几何标定参数,具体包括:获取初始的射线源参数和初始的探测器参数,其中,所述射线源参数用于表示所述射线源在标定系统中的位置,所述探测器参数用于表示所述探测器在所述标定系统中的位置;根据初始的射线源参数、初始的探测器参数以及所述几何标定模体相对于所述射线源和所述探测器的位置关系,通过几何计算获得所述几何标定模体在所述探测器上的理论投影位置;根据所述实际投影位置和所述理论投影位置,对所述射线源参数和所述探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数;以及将所述优化的射线源参数和优化的探测器参数确定为几何标定参数。The calibrating of the ray source parameters and the detector parameters to obtain optimized ray source parameters and optimized detector parameters, and determining the optimized ray source parameters and optimized detector parameters as geometric calibration parameters, specifically includes: obtaining initial ray source parameters and initial detector parameters, wherein the ray source parameters are used to represent the position of the ray source in the calibration system, and the detector parameters are used to represent the position of the detector in the calibration system; obtaining the theoretical projection position of the geometric calibration phantom on the detector through geometric calculation according to the initial ray source parameters, the initial detector parameters and the positional relationship of the geometric calibration phantom relative to the ray source and the detector; calibrating the ray source parameters and the detector parameters according to the actual projection position and the theoretical projection position to obtain optimized ray source parameters and optimized detector parameters; and determining the optimized ray source parameters and optimized detector parameters as geometric calibration parameters.

根据一些示例性的实施例,根据所述实际投影位置和所述理论投影位置,对所述射线源参数和所述探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,包括:构建所述实际投影位置和所述理论投影位置之间的偏差关于射线源参数和探测器参数的优化函数,在所述优化函数中,所述偏差为因变量,所述射线源参数和所述探测器参数为自变量。According to some exemplary embodiments, the ray source parameters and the detector parameters are calibrated according to the actual projection position and the theoretical projection position to obtain optimized ray source parameters and optimized detector parameters, including: constructing an optimization function of the deviation between the actual projection position and the theoretical projection position with respect to ray source parameters and detector parameters, in which the deviation is a dependent variable, and the ray source parameters and the detector parameters are independent variables.

根据一些示例性的实施例,根据所述实际投影位置和所述理论投影位置,对所述射线源参数和所述探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,还包括:根据所述优化函数,将所述偏差取值最小值时对应的射线源参数和探测器参数确定为优化的射线源参数和优化的探测器参数,将所述优化的射线源参数和优化的探测器参数确定为几何标定参数。According to some exemplary embodiments, the ray source parameters and the detector parameters are calibrated according to the actual projection position and the theoretical projection position to obtain optimized ray source parameters and optimized detector parameters, and also include: according to the optimization function, determining the ray source parameters and the detector parameters corresponding to the minimum value of the deviation as the optimized ray source parameters and the optimized detector parameters, and determining the optimized ray source parameters and the optimized detector parameters as geometric calibration parameters.

根据一些示例性的实施例,所述射线源包括Ns个靶点,所述Ns个靶点沿第一方向间隔分布,其中,Ns为大于等于2的正整数;根据所述实际投影位置和所述理论投影位置,对所述射线源参数和所述探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,包括:构建优化函数,所述优化函数包括投影位置约束项和靶点距离约束项,其中,所述投影位置约束项为所述实际投影位置和所述理论投影位置之间的偏差关于射线源参数和探测器参数的第一函数;所述靶点距离约束项为相邻的两个靶点之间的实际距离和理论距离之间的偏差关于射线源参数和探测器参数的第二函数。According to some exemplary embodiments, the ray source includes N s target points, and the N s target points are spaced apart along a first direction, wherein N s is a positive integer greater than or equal to 2; the ray source parameters and the detector parameters are calibrated according to the actual projection position and the theoretical projection position to obtain optimized ray source parameters and optimized detector parameters, including: constructing an optimization function, the optimization function including a projection position constraint term and a target distance constraint term, wherein the projection position constraint term is a first function of the deviation between the actual projection position and the theoretical projection position with respect to the ray source parameters and the detector parameters; the target distance constraint term is a second function of the deviation between the actual distance and the theoretical distance between two adjacent target points with respect to the ray source parameters and the detector parameters.

根据一些示例性的实施例,在所述优化函数中,所述投影位置约束项具有第一权重值,所述靶点距离约束项具有第二权重值。According to some exemplary embodiments, in the optimization function, the projection position constraint term has a first weight value, and the target point distance constraint term has a second weight value.

根据一些示例性的实施例,根据所述实际投影位置和所述理论投影位置,对所述射线源参数和所述探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,还包括:根据所述优化函数,将所述实际投影位置和所述理论投影位置之间的偏差和相邻的两个靶点之间的实际距离和理论距离之间的偏差的加权求和取值最小值时对应的射线源参数和探测器参数确定为优化的射线源参数和优化的探测器参数,将所述优化的射线源参数和优化的探测器参数确定为几何标定参数。According to some exemplary embodiments, the ray source parameters and the detector parameters are calibrated according to the actual projection position and the theoretical projection position to obtain optimized ray source parameters and optimized detector parameters, and also include: according to the optimization function, determining the ray source parameters and the detector parameters corresponding to the minimum value of the weighted sum of the deviation between the actual projection position and the theoretical projection position and the deviation between the actual distance and the theoretical distance between two adjacent target points as the optimized ray source parameters and the optimized detector parameters, and determining the optimized ray source parameters and the optimized detector parameters as geometric calibration parameters.

根据一些示例性的实施例,所述根据所述几何关系和所述能谱标定模体的物理属性,对能谱参数进行标定,以获取优化的能谱参数,并将所述优化的能谱参数确定为能谱标定参数,具体包括:获取所述能谱标定模体的物理属性,其中,所述物理属性是根据所述能谱标定模体的组成材料预先确定的;基于所述能谱标定模体的物理属性和所述几何关系,使用预定的多个基础能谱计算理论投影数据;根据所述理论投影数据和所述实际投影数据,对能谱参数进行标定,以获取优化的能谱参数;以及将所述优化的能谱参数确定为能谱标定参数。According to some exemplary embodiments, the energy spectrum parameters are calibrated according to the geometric relationship and the physical properties of the energy spectrum calibration phantom to obtain optimized energy spectrum parameters, and the optimized energy spectrum parameters are determined as energy spectrum calibration parameters, specifically including: obtaining the physical properties of the energy spectrum calibration phantom, wherein the physical properties are predetermined based on the constituent materials of the energy spectrum calibration phantom; calculating theoretical projection data using a predetermined plurality of basic energy spectra based on the physical properties of the energy spectrum calibration phantom and the geometric relationship; calibrating the energy spectrum parameters according to the theoretical projection data and the actual projection data to obtain optimized energy spectrum parameters; and determining the optimized energy spectrum parameters as energy spectrum calibration parameters.

根据一些示例性的实施例,所述根据所述几何关系和所述能谱标定模体的物理属性,对能谱参数进行标定,以获取优化的能谱参数,并将所述优化的能谱参数确定为能谱标定参数,具体包括:According to some exemplary embodiments, the calibrating the energy spectrum parameters according to the geometric relationship and the physical properties of the energy spectrum calibration phantom to obtain optimized energy spectrum parameters, and determining the optimized energy spectrum parameters as energy spectrum calibration parameters specifically includes:

执行循环过程直至满足预设条件,所述第一循环过程包括:The loop process is executed until a preset condition is met, wherein the first loop process includes:

根据能谱信息,对所述能谱标定模体进行图像重建,根据所述图像重建的结果获取所述能谱标定模体的物理属性;Performing image reconstruction on the energy spectrum calibration phantom according to the energy spectrum information, and obtaining physical properties of the energy spectrum calibration phantom according to a result of the image reconstruction;

基于所述能谱标定模体的物理属性和所述几何关系,使用预定的多个基础能谱计算理论投影数据;Based on the physical properties of the energy spectrum calibration phantom and the geometric relationship, using a predetermined plurality of basic energy spectra to calculate theoretical projection data;

根据所述理论投影数据和所述实际投影数据,对能谱参数进行标定,以获取优化的能谱参数;和Calibrate energy spectrum parameters according to the theoretical projection data and the actual projection data to obtain optimized energy spectrum parameters; and

基于所述优化的能谱参数,获取能谱信息;以及Based on the optimized energy spectrum parameters, acquiring energy spectrum information; and

将所述第一循环过程中最后一次获得的优化的能谱参数,确定为能谱标定参数。The optimized energy spectrum parameters obtained for the last time during the first cycle are determined as energy spectrum calibration parameters.

根据一些示例性的实施例,所述根据所述理论投影数据和所述实际投影数据,对能谱参数进行标定,以获取优化的能谱参数,包括:构建所述理论投影数据和所述实际投影数据之间的偏差关于能谱参数的优化函数;以及根据所述优化函数,对能谱参数进行标定,以获取优化的能谱参数。According to some exemplary embodiments, the calibrating the energy spectrum parameters according to the theoretical projection data and the actual projection data to obtain optimized energy spectrum parameters includes: constructing an optimization function of the deviation between the theoretical projection data and the actual projection data with respect to the energy spectrum parameters; and calibrating the energy spectrum parameters according to the optimization function to obtain optimized energy spectrum parameters.

根据一些示例性的实施例,所述几何标定模体包括至少一个金属丝;或者,所述几何标定模体包括多个金属丝,所述多个金属丝以彼此不同的半径和/或彼此不同的角度分布在所述旋转台上。According to some exemplary embodiments, the geometric calibration phantom includes at least one metal wire; or, the geometric calibration phantom includes a plurality of metal wires, and the plurality of metal wires are distributed on the rotating table with different radii and/or different angles from each other.

根据一些示例性的实施例,所述能谱标定模体包括分别由多种材料构成的多个部分,所述多种材料中的任意两者的以下至少一种属性不相同:密度,原子序数。According to some exemplary embodiments, the energy spectrum calibration phantom includes a plurality of parts respectively made of a plurality of materials, and at least one of the following properties of any two of the plurality of materials is different: density, atomic number.

根据一些示例性的实施例,所述标定系统包括旋转台,所述几何标定模体和所述能谱标定模体中的至少一个位于所述旋转台上;所述通过所述探测器采集经过所述扫描区域的射线,获得探测器数据,包括:控制所述射线源发出射线;控制所述旋转台旋转,以带动所述几何标定模体和所述能谱标定模体中的至少一个旋转m圈,其中,m为大于等于1的正整数;以及在所述几何标定模体和所述能谱标定模体中的至少一个旋转m圈的过程中,所述探测器采集从所述射线源发出且经过所述扫描区域的射线。According to some exemplary embodiments, the calibration system includes a rotating table, and at least one of the geometric calibration phantom and the energy spectrum calibration phantom is located on the rotating table; the detector collects the rays passing through the scanning area to obtain the detector data, including: controlling the ray source to emit rays; controlling the rotating table to rotate to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to rotate m times, wherein m is a positive integer greater than or equal to 1; and during the process of at least one of the geometric calibration phantom and the energy spectrum calibration phantom rotating m times, the detector collects the rays emitted from the ray source and passing through the scanning area.

根据一些示例性的实施例,所述标定系统包括升降台,所述几何标定模体和所述能谱标定模体中的至少一个位于所述升降台上;所述通过所述探测器采集经过所述扫描区域的射线,获得探测器数据,包括:控制所述射线源发出射线;以及控制所述升降台升降,以带动所述几何标定模体和所述能谱标定模体中的至少一个升降。According to some exemplary embodiments, the calibration system includes a lifting platform, and at least one of the geometric calibration phantom and the energy spectrum calibration phantom is located on the lifting platform; the detector collects the rays passing through the scanning area to obtain the detector data, including: controlling the ray source to emit rays; and controlling the lifting platform to rise and fall, so as to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to rise and fall.

根据一些示例性的实施例,所述射线源包括Ns个靶点,所述Ns个靶点沿第一方向间隔分布,其中,Ns为大于等于2的正整数;所述通过所述探测器采集经过所述扫描区域的射线,获得探测器数据,包括:控制所述Ns个靶点按照设定顺序发出射线;以及在所述Ns个靶点按照设定顺序发出射线的过程中,所述探测器采集从所述射线源发出且经过所述扫描区域的射线。According to some exemplary embodiments, the ray source includes N s target points, and the N s target points are spaced apart along a first direction, wherein N s is a positive integer greater than or equal to 2; the collecting of rays passing through the scanning area by the detector to obtain detector data includes: controlling the N s target points to emit rays in a set order; and in the process of the N s target points emitting rays in the set order, the detector collecting rays emitted from the ray source and passing through the scanning area.

根据一些示例性的实施例,所述标定系统包括旋转台,所述几何标定模体和所述能谱标定模体中的至少一个位于所述旋转台上;所述射线源包括Ns个靶点,所述Ns个靶点沿第一方向间隔分布,其中,Ns为大于等于2的正整数;所述通过所述探测器采集经过所述扫描区域的射线,获得探测器数据,包括:控制所述Ns个靶点按照设定顺序发出射线;控制所述旋转台旋转,以带动所述几何标定模体和所述能谱标定模体中的至少一个旋转m圈,其中,m为大于等于1的正整数;以及在所述Ns个靶点按照设定顺序发出射线和所述几何标定模体和所述能谱标定模体中的至少一个旋转m圈的过程中,所述探测器采集从所述射线源发出且经过所述扫描区域的射线。According to some exemplary embodiments, the calibration system includes a rotating table, and at least one of the geometric calibration phantom and the energy spectrum calibration phantom is located on the rotating table; the radiation source includes Ns target points, and the Ns target points are spaced along a first direction, wherein Ns is a positive integer greater than or equal to 2; the detector collects the rays passing through the scanning area to obtain the detector data, comprising: controlling the Ns target points to emit rays in a set order; controlling the rotating table to rotate so as to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to rotate m times, wherein m is a positive integer greater than or equal to 1; and in the process of the Ns target points emitting rays in a set order and at least one of the geometric calibration phantom and the energy spectrum calibration phantom rotating m times, the detector collects the rays emitted from the radiation source and passing through the scanning area.

根据一些示例性的实施例,在确定所述射线源、所述能谱标定模体和所述探测器之间的相对位置之前,所述方法还包括:标定承载所述能谱标定模体的标定装置主体相对于所述射线源和所述探测器的相对位置。According to some exemplary embodiments, before determining the relative positions among the ray source, the energy spectrum calibration phantom and the detector, the method further comprises: calibrating the relative position of a calibration device body carrying the energy spectrum calibration phantom relative to the ray source and the detector.

根据一些示例性的实施例,所述根据所述几何关系和所述能谱标定模体的物理属性,对能谱参数进行标定,以获取优化的能谱参数,并将所述优化的能谱参数确定为能谱标定参数,具体包括:According to some exemplary embodiments, the calibrating the energy spectrum parameters according to the geometric relationship and the physical properties of the energy spectrum calibration phantom to obtain optimized energy spectrum parameters, and determining the optimized energy spectrum parameters as energy spectrum calibration parameters specifically includes:

执行循环过程直至满足预设条件,所述第一循环过程包括:The loop process is executed until a preset condition is met, wherein the first loop process includes:

根据能谱信息,对所述几何标定模体和所述能谱标定模体进行图像重建,以获取第一重建图像;对所述第一重建图像进行分割处理,分割出所述几何标定模体和所述能谱标定模体,以获取第二重建图像;和根据所述第二重建图像获取所述能谱标定模体的物理属性;According to the energy spectrum information, image reconstruction is performed on the geometric calibration phantom and the energy spectrum calibration phantom to obtain a first reconstructed image; segmentation is performed on the first reconstructed image to segment the geometric calibration phantom and the energy spectrum calibration phantom to obtain a second reconstructed image; and physical properties of the energy spectrum calibration phantom are obtained according to the second reconstructed image;

基于所述能谱标定模体的物理属性和所述几何关系,使用预定的多个基础能谱计算理论投影数据;Based on the physical properties of the energy spectrum calibration phantom and the geometric relationship, using a predetermined plurality of basic energy spectra to calculate theoretical projection data;

根据所述理论投影数据和所述实际投影数据,对能谱参数进行标定,以获取优化的能谱参数;和Calibrate energy spectrum parameters according to the theoretical projection data and the actual projection data to obtain optimized energy spectrum parameters; and

基于所述优化的能谱参数,获取能谱信息;以及Based on the optimized energy spectrum parameters, acquiring energy spectrum information; and

将所述第一循环过程中最后一次获得的优化的能谱参数,确定为能谱标定参数。The optimized energy spectrum parameters obtained for the last time during the first cycle are determined as energy spectrum calibration parameters.

在又一方面,提供一种用于标定扫描成像设备的标定系统,其中,所述标定系统包括:标定装置主体;设置于所述标定装置主体上的几何标定模体和能谱标定模体中的至少一个;驱动件,所述驱动件用于驱动所述几何标定模体和所述能谱标定模体中的至少一个运动;以及控制器,所述控制器被配置为根据如上所述的标定方法,对扫描成像设备进行标定。On the other hand, a calibration system for calibrating a scanning imaging device is provided, wherein the calibration system comprises: a calibration device body; at least one of a geometric calibration phantom and an energy spectrum calibration phantom disposed on the calibration device body; a driving member, the driving member being used to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to move; and a controller, the controller being configured to calibrate the scanning imaging device according to the calibration method as described above.

在还又一方面,提供一种用于标定扫描成像设备的标定系统,其中,所述标定系统包括:底座;连接于所述底座上的旋转台;设置于所述旋转台上的几何标定模体和能谱标定模体中的至少一个,所述几何标定模体和所述能谱标定模体中的至少一个位于所述旋转台上;以及驱动件,所述驱动件用于驱动所述旋转台旋转,以带动所述几何标定模体和所述能谱标定模体中的至少一个旋转,其中,所述几何标定模体包括至少一个金属丝;或者,所述几何标定模体包括多个金属丝,所述多个金属丝以彼此不同的半径和/或彼此不同的角度分布在所述旋转台上;和/或,所述能谱标定模体包括分别由多种材料构成的多个部分,所述多种材料中的任意两者的以下至少一种属性不相同:密度,原子序数。On the other hand, a calibration system for calibrating a scanning imaging device is provided, wherein the calibration system comprises: a base; a rotating table connected to the base; at least one of a geometric calibration phantom and an energy spectrum calibration phantom disposed on the rotating table, and at least one of the geometric calibration phantom and the energy spectrum calibration phantom is located on the rotating table; and a driving member, wherein the driving member is used to drive the rotating table to rotate so as to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to rotate, wherein the geometric calibration phantom comprises at least one metal wire; or, the geometric calibration phantom comprises a plurality of metal wires, and the plurality of metal wires are distributed on the rotating table with different radii and/or different angles from each other; and/or, the energy spectrum calibration phantom comprises a plurality of parts respectively composed of a plurality of materials, and at least one of the following properties of any two of the plurality of materials is different: density, atomic number.

根据一些示例性的实施例,所述标定系统还包括:升降台,所述升降台连接于所述底座上,所述旋转台设置于所述升降台上。According to some exemplary embodiments, the calibration system further includes: a lifting platform, wherein the lifting platform is connected to the base, and the rotating platform is disposed on the lifting platform.

本公开的附加方面和优点将在下面的描述中部分给出,部分将从下面的描述中变得明显,或通过本公开的实践了解到。Additional aspects and advantages of the present disclosure will be given in part in the following description and in part will be obvious from the following description or will be learned through practice of the present disclosure.

附图说明BRIEF DESCRIPTION OF THE DRAWINGS

为了更完整地理解本公开及其优势,现在将参考结合附图的以下描述,其中:For a more complete understanding of the present disclosure and its advantages, reference will now be made to the following description taken in conjunction with the accompanying drawings, in which:

图1示意性示出了射线源、被扫描对象和探测器之间的投影关系的示意图。FIG1 schematically shows a schematic diagram of the projection relationship between a ray source, a scanned object and a detector.

图2为根据本公开的一些示例性实施例的静态CT设备的结构示意图。FIG. 2 is a schematic structural diagram of a static CT device according to some exemplary embodiments of the present disclosure.

图3A为根据本公开的一些示例性实施例的静态CT设备包括的扫描级的结构示意图。FIG. 3A is a schematic structural diagram of a scanning stage included in a static CT device according to some exemplary embodiments of the present disclosure.

图3B为根据本公开的另一些示例性实施例的静态CT设备包括的扫描级的结构示意图。FIG. 3B is a schematic structural diagram of a scanning stage included in a static CT device according to other exemplary embodiments of the present disclosure.

图4A是根据本公开的一些示例性实施例的标定系统的结构示意图。FIG. 4A is a schematic diagram of the structure of a calibration system according to some exemplary embodiments of the present disclosure.

图4B是从另一角度观察的根据本公开的一些示例性实施例的标定系统的结构示意图。FIG. 4B is a schematic structural diagram of a calibration system according to some exemplary embodiments of the present disclosure, viewed from another angle.

图4C是根据本公开的一些示例性实施例的标定系统的结构示意图,其示意性示出了一个金属丝。FIG. 4C is a schematic diagram of the structure of a calibration system according to some exemplary embodiments of the present disclosure, which schematically shows a metal wire.

图4D是图4C所示的标定系统的侧视图。4D is a side view of the calibration system shown in FIG. 4C .

图4E是根据本公开的一些示例性实施例的标定系统的结构示意图,其示意性示出了多个金属丝。FIG. 4E is a schematic diagram of the structure of a calibration system according to some exemplary embodiments of the present disclosure, which schematically shows a plurality of metal wires.

图4F为图4E中所示的四个金属丝在旋转台上的投影图。FIG. 4F is a projection diagram of the four metal wires shown in FIG. 4E on the rotating stage.

图5是根据本公开的一些示例性实施例的标定方法的流程图。FIG. 5 is a flow chart of a calibration method according to some exemplary embodiments of the present disclosure.

图6是根据本公开的另一些示例性实施例的标定方法的流程图。FIG. 6 is a flowchart of a calibration method according to some other exemplary embodiments of the present disclosure.

图7是根据本公开的一些示例性实施例的标定方法中的几何标定步骤的流程图。FIG. 7 is a flowchart of a geometric calibration step in a calibration method according to some exemplary embodiments of the present disclosure.

图8A是根据本公开的一些示例性实施例的标定方法中的几何标定步骤的获取优化的射线源参数和优化的探测器参数的示例性流程图。FIG8A is an exemplary flowchart of obtaining optimized ray source parameters and optimized detector parameters in a geometric calibration step in a calibration method according to some exemplary embodiments of the present disclosure.

图8B是根据本公开的另一些示例性实施例的标定方法中的几何标定步骤的获取优化的射线源参数和优化的探测器参数的示例性流程图。FIG8B is an exemplary flowchart of obtaining optimized ray source parameters and optimized detector parameters in a geometric calibration step in a calibration method according to other exemplary embodiments of the present disclosure.

图9是根据本公开的一些示例性实施例的标定方法中能谱标定步骤的流程图。FIG. 9 is a flow chart of an energy spectrum calibration step in a calibration method according to some exemplary embodiments of the present disclosure.

图10是根据本公开的另一些示例性实施例的标定方法中能谱标定步骤的流程图。FIG. 10 is a flow chart of energy spectrum calibration steps in a calibration method according to other exemplary embodiments of the present disclosure.

图11是根据本公开的一些示例性实施例的标定方法中的获取优化的能谱参数的示例性流程图。FIG. 11 is an exemplary flowchart of obtaining optimized energy spectrum parameters in a calibration method according to some exemplary embodiments of the present disclosure.

图12示意性示出了根据本公开的示例性实施例的标定系统的控制器的结构框图。FIG. 12 schematically shows a structural block diagram of a controller of a calibration system according to an exemplary embodiment of the present disclosure.

具体实施方式DETAILED DESCRIPTION

以下,将参照附图来描述本公开的实施例。但是应该理解,这些描述只是示例性的,而并非要限制本公开的范围。此外,在以下说明中,省略了对公知结构和技术的描述,以避免不必要地混淆本公开的概念。另外,本公开以下提供的各个实施例以及实施例中的技术特征可以以任意方式相互组合。Hereinafter, embodiments of the present disclosure will be described with reference to the accompanying drawings. However, it should be understood that these descriptions are exemplary only and are not intended to limit the scope of the present disclosure. In addition, in the following description, descriptions of well-known structures and technologies are omitted to avoid unnecessary confusion of the concepts of the present disclosure. In addition, the various embodiments provided below in the present disclosure and the technical features in the embodiments can be combined with each other in any manner.

在此使用的术语仅仅是为了描述具体实施例,而并非意在限制本公开。此外,在此使用的术语“包括”、“包含”等表明了所述特征、步骤、操作和/或部件的存在,但是并不排除存在或添加一个或多个其他特征、步骤、操作或部件。在此使用的所有术语(包括技术和科学术语)具有本领域技术人员通常所理解的含义,除非另外定义。应注意,这里使用的术语应解释为具有与本说明书的上下文相一致的含义,而不应以理想化或过于刻板的方式来解释。The terms used herein are only for describing specific embodiments and are not intended to limit the present disclosure. In addition, the terms "including", "comprising", etc. used herein indicate the presence of the features, steps, operations and/or components, but do not exclude the presence or addition of one or more other features, steps, operations or components. All terms (including technical and scientific terms) used herein have the meanings commonly understood by those skilled in the art, unless otherwise defined. It should be noted that the terms used herein should be interpreted as having meanings consistent with the context of this specification, and should not be interpreted in an idealized or overly rigid manner.

在本公开的描述中,需要理解的是,术语“中心”、“纵向”、“横向”、“长度”、“宽度”、“厚度”、“上”、“下”、“前”、“后”、“左”、“右”、“竖直”、“水平”、“顶”、“底”“内”、“外”、“顺时针”、“逆时针”、“轴向”、“径向”、“周向”等指示的方位或位置关系为基于附图所示的方位或位置关系,仅是为了便于描述本公开和简化描述,而不是指示或暗示所指的装置或元件必须具有特定的方位、以特定的方位构造和操作,因此不能理解为对本公开的限制。此外,限定有“第一”、“第二”的特征可以明示或者隐含地包括一个或者更多个该特征。在本公开的描述中,除非另有说明,“多个”的含义是两个或两个以上。In the description of the present disclosure, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present disclosure and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present disclosure. In addition, features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present disclosure, unless otherwise specified, "multiple" means two or more.

在本公开的描述中,需要说明的是,除非另有明确的规定和限定,术语“安装”、“相连”、“连接”应做广义理解,例如,可以是固定连接,也可以是可拆卸连接,或一体地连接;可以是机械连接,也可以是电连接;可以是直接相连,也可以通过中间媒介间接相连,可以是两个元件内部的连通。对于本领域的普通技术人员而言,可以具体情况理解上述术语在本公开中的具体含义。In the description of the present disclosure, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present disclosure can be understood according to specific circumstances.

在本公开的说明书中,计算机断层扫描(Computed Tomography,简称为CT)成像指利用射线对检测对象进行断层扫描后,由探测器收得的模拟信号再变成数字信号,经电子计算机计算出每一个象素的衰减系数,再重建图像,从而能显示出检测对象各部位的断层结构。In the present specification, computed tomography (CT) imaging refers to the use of radiation to perform a cross-sectional scan of the object to be detected. The analog signal received by the detector is converted into a digital signal, and the attenuation coefficient of each pixel is calculated by an electronic computer. The image is then reconstructed to display the cross-sectional structure of each part of the object to be detected.

图1示意性示出了射线源、被扫描对象和探测器之间的投影关系的示意图。参照图1,在本公开的实施例中,射线源S发出的射线(例如X射线,γ射线等)入射到被扫描对象OB上,透射通过被扫描对象OB的射线被探测器D检测到。被扫描对象OB上的空间点X通过射线源S被作用到探测器D的图像点Y。在正向投影(也称为前向投影)中,已知被扫描对象OB上的空间点的像素值,求取探测器D上的图像点的投影值。在反向投影(也称为后向投影)中,已知探测器D上的图像点的投影值,求取被扫描对象OB上的空间点的像素值。FIG1 schematically shows a schematic diagram of the projection relationship between a ray source, a scanned object, and a detector. Referring to FIG1 , in an embodiment of the present disclosure, rays (such as X-rays, gamma rays, etc.) emitted by a ray source S are incident on the scanned object OB, and rays transmitted through the scanned object OB are detected by a detector D. A spatial point X on the scanned object OB is acted upon by the ray source S to an image point Y on the detector D. In a forward projection (also called a forward projection), the pixel value of a spatial point on the scanned object OB is known, and the projection value of the image point on the detector D is obtained. In a reverse projection (also called a backward projection), the projection value of an image point on the detector D is known, and the pixel value of a spatial point on the scanned object OB is obtained.

电子计算机断层扫描技术由于能够消除物体重叠的影响,在安全检查、医疗领域等场合中发挥了重要作用。传统的CT采用滑环装置通过X射线源和探测器的旋转来获取不同角度上的投影数据,通过重建方法来获取断层图像,从而获得被检测行李物品的内部信息。传统的CT装置在数据采集过程中通常采用滑环旋转,不但扫描速度有限、体积庞大,而且机械加工精度要求高,成本较高,限制了其在实际中的广泛应用。近些年,碳纳米管X光管技术进入了实用领域。与传统射线源不同,它无须利用高温来产生射线,而是根据碳纳米管尖端放电原理产生阴极射线,打靶产生X光。其优点是可以快速开启和关闭,且体积更小。把这种X射线源排布成环状,进行不同角度下对物体的照射,就可以制成无需旋转的“静态CT”,大大提高了射线成像的速度,同时由于省去了滑环的结构,节省了成本,对于安全检查等领域具有十分重要的意义。Computer tomography technology plays an important role in security inspection, medical field and other occasions because it can eliminate the influence of overlapping objects. Traditional CT uses slip ring device to obtain projection data at different angles through the rotation of X-ray source and detector, and obtains tomographic images through reconstruction method, so as to obtain internal information of the detected luggage items. Traditional CT devices usually use slip ring rotation in the data acquisition process, which not only has limited scanning speed and large volume, but also requires high machining precision and high cost, which limits its wide application in practice. In recent years, carbon nanotube X-ray tube technology has entered the practical field. Unlike traditional ray sources, it does not need to use high temperature to generate rays, but generates cathode rays based on the principle of discharge at the tip of carbon nanotubes, and generates X-rays by hitting the target. Its advantages are that it can be turned on and off quickly and has a smaller size. By arranging this X-ray source in a ring shape and irradiating objects at different angles, a "static CT" that does not need to rotate can be made, which greatly improves the speed of ray imaging. At the same time, since the slip ring structure is omitted, the cost is saved, which is of great significance for security inspection and other fields.

图2为根据本公开的一些示例性实施例的静态CT设备的结构示意图。参照图2,根据本公开实施例的静态CT设备可以包括扫描级、传送机构110、控制装置140和成像装置130。例如,所述扫描级可以包括射线源、探测器和采集装置。Fig. 2 is a schematic diagram of the structure of a static CT device according to some exemplary embodiments of the present disclosure. Referring to Fig. 2, the static CT device according to an embodiment of the present disclosure may include a scanning stage, a transmission mechanism 110, a control device 140 and an imaging device 130. For example, the scanning stage may include a ray source, a detector and a collection device.

例如,在本公开的实施例中,射线源可以为分布式射线源,所述分布式射线源可以包括多个靶点,例如,多个X靶点。在分布式X射线源中,靶点是指射线源的发射点或焦点。具体地,高能电子从阴极发射并轰击金属阳极靶,从而产生X射线。发射的X射线的能量取决于阳极靶的材料,而X射线的强度取决于轰击阳极靶的电子流强和电子能量。在分布式X射线源中,多个阴极与多个靶点一一对应,使得多个靶点接收来自多个阴极的电子束,以产生多束X射线。这种设计使得分布式X射线源能够实现使用较少的阴极组件产生较多X射线辐射源的效果,提高了系统的稳定性,减少了阴极组件的使用数量,降低了设备的生产成本。For example, in an embodiment of the present disclosure, the ray source may be a distributed ray source, and the distributed ray source may include multiple target points, for example, multiple X-ray target points. In a distributed X-ray source, the target point refers to the emission point or focus of the ray source. Specifically, high-energy electrons are emitted from the cathode and bombard the metal anode target, thereby generating X-rays. The energy of the emitted X-rays depends on the material of the anode target, and the intensity of the X-rays depends on the electron flux and electron energy bombarding the anode target. In a distributed X-ray source, multiple cathodes correspond one-to-one to multiple target points, so that multiple target points receive electron beams from multiple cathodes to generate multiple beams of X-rays. This design enables the distributed X-ray source to achieve the effect of using fewer cathode components to generate more X-ray radiation sources, improves the stability of the system, reduces the number of cathode components used, and reduces the production cost of the equipment.

在利用分布式射线源的静态CT设备中,通过将多个靶点组合在一起,并在不同的角度上按照设定顺序激活它们,可以从各个角度获取多个投影数据集。这些投影数据集可以用于计算机重建算法来生成高质量的横截面图像。使用分布式X射线源的一个优势是可以减少伪影和提高图像质量。通过使用多个靶点,X射线束的发射位置分布更加均匀,可以提供更多的投影角度和数据,减少重建图像中的伪影,并提供更准确的解剖信息。也就是说,分布式X射线源中的靶点是指发射X射线束的点或区域,它们的分布形式有助于获得高质量的投影数据,用于静态CT图像的重建。In static CT devices that utilize distributed ray sources, multiple projection data sets can be acquired from various angles by combining multiple targets together and activating them in a set order at different angles. These projection data sets can be used in computer reconstruction algorithms to generate high-quality cross-sectional images. One advantage of using a distributed X-ray source is that it can reduce artifacts and improve image quality. By using multiple targets, the emission positions of the X-ray beam are more evenly distributed, which can provide more projection angles and data, reduce artifacts in the reconstructed image, and provide more accurate anatomical information. In other words, the targets in a distributed X-ray source refer to the points or areas that emit X-ray beams, and their distribution form helps to obtain high-quality projection data for the reconstruction of static CT images.

在本公开的实施例中,分布式射线源中的多个靶点可以沿预定的第一方向布置。例如,预定的第一方向可以为直线方向,或者,可以为弧形方向。本公开的实施例并不对分布式射线源中靶点的布置形式做特别的限制。In the embodiments of the present disclosure, multiple target points in the distributed ray source may be arranged along a predetermined first direction. For example, the predetermined first direction may be a straight line direction, or may be an arc direction. The embodiments of the present disclosure do not impose any particular restrictions on the arrangement of the target points in the distributed ray source.

图3A为根据本公开的一些示例性实施例的静态CT设备包括的扫描级的结构示意图。图3B为根据本公开的另一些示例性实施例的静态CT设备包括的扫描级的结构示意图。参照图3A和图3B,在本公开的实施例中,所述静态CT设备包括分布式射线源20和探测器30,所述分布式射线源20可以包括多个靶点210。在一些实施例中,如图3A所示,多个靶点210可以呈弧形布置,相应地,所述探测器30可以包括呈弧形或圆形布置的多个探测单元310。在一些实施例中,如图3B所示,多个靶点210可以沿直线布置,相应地,所述探测器30可以包括沿直线布置的多个探测单元310。需要说明的是,在图2至图3B的实施例中,仅示意性示出了根据本公开的一些示例性实施例的静态CT设备的结构示意图,而不是本公开的全部实施例。在本公开的实施例中,可以采用任何合适布置的分布式射线源和探测器。FIG. 3A is a schematic diagram of the structure of a scanning stage included in a static CT device according to some exemplary embodiments of the present disclosure. FIG. 3B is a schematic diagram of the structure of a scanning stage included in a static CT device according to some other exemplary embodiments of the present disclosure. Referring to FIG. 3A and FIG. 3B, in an embodiment of the present disclosure, the static CT device includes a distributed ray source 20 and a detector 30, and the distributed ray source 20 may include a plurality of targets 210. In some embodiments, as shown in FIG. 3A, the plurality of targets 210 may be arranged in an arc shape, and accordingly, the detector 30 may include a plurality of detection units 310 arranged in an arc shape or a circle. In some embodiments, as shown in FIG. 3B, the plurality of targets 210 may be arranged along a straight line, and accordingly, the detector 30 may include a plurality of detection units 310 arranged along a straight line. It should be noted that in the embodiments of FIG. 2 to FIG. 3B, only schematic diagrams of the structure of a static CT device according to some exemplary embodiments of the present disclosure are schematically shown, rather than all embodiments of the present disclosure. In an embodiment of the present disclosure, any appropriately arranged distributed ray source and detector may be used.

在本公开的实施例中,所述多个靶点210分别朝向被扫描对象120发出射线,多个探测单元310用于检测经过所述被扫描对象120的射线。例如,在图3A和图3B所示的实施例中,多个靶点210发出X射线,多个探测单元310接受从多个靶点210发出且经过被扫描对象120的部分X射线。这样,在射线源20与探测器30之间,形成对被扫描对象120进行扫描的扫描区域。在该扫描区域中,位于扫描区域的大致中间位置,且垂直于传送机构110的传送方向的至少一个平面,可以称为扫描平面。In the embodiment of the present disclosure, the multiple target points 210 respectively emit radiation toward the scanned object 120, and the multiple detection units 310 are used to detect the radiation passing through the scanned object 120. For example, in the embodiment shown in FIG. 3A and FIG. 3B, the multiple target points 210 emit X-rays, and the multiple detection units 310 receive part of the X-rays emitted from the multiple target points 210 and passing through the scanned object 120. In this way, a scanning area for scanning the scanned object 120 is formed between the ray source 20 and the detector 30. In the scanning area, at least one plane located in the approximate middle position of the scanning area and perpendicular to the conveying direction of the conveying mechanism 110 can be called a scanning plane.

示例地,探测单元310可以包括至少一个探测器晶体。例如,探测单元310可以包括一个探测器晶体。再例如,探测单元310可以包括沿多个探测器晶体,多个探测器晶体可以沿一维方向排列,或者,多个探测器晶体可以沿二维方向排列。For example, the detection unit 310 may include at least one detector crystal. For example, the detection unit 310 may include one detector crystal. For another example, the detection unit 310 may include a plurality of detector crystals, and the plurality of detector crystals may be arranged along a one-dimensional direction, or the plurality of detector crystals may be arranged along a two-dimensional direction.

应该理解,每个探测器晶体是探测器的基本单元,它们可以吸收射线(例如X射线)并将其转换为其他形式的能量,例如光或电信号。例如,探测器晶体的材料可以包括氧化物和卤化物(例如碘化物和氟化物)等。It should be understood that each detector crystal is a basic unit of the detector, which can absorb radiation (such as X-rays) and convert it into other forms of energy, such as light or electrical signals. For example, the material of the detector crystal can include oxides and halides (such as iodides and fluorides), etc.

例如,在图2所示的实施例中,传送机构110承载被扫描对象120并驱动被扫描对象120作直线运动。控制装置140控制射线源20的多个靶点210的出束顺序,使得探测器30输出对应于投影数据的数字信号。成像装置130基于所述数字信号重建所述被扫描对象120的CT图像。For example, in the embodiment shown in FIG2 , the transport mechanism 110 carries the scanned object 120 and drives the scanned object 120 to move in a straight line. The control device 140 controls the beam-emission sequence of the multiple target points 210 of the ray source 20, so that the detector 30 outputs a digital signal corresponding to the projection data. The imaging device 130 reconstructs a CT image of the scanned object 120 based on the digital signal.

需要说明的是,在本公开的实施例中,成像装置130可以采用相关的各种已知的重建算法来重建被扫描对象的CT图像。例如,重建算法可以选用迭代、解析或其他重建算法,本公开的实施例不对重建算法做特别限制。It should be noted that in the embodiments of the present disclosure, the imaging device 130 may use various known reconstruction algorithms to reconstruct the CT image of the scanned object. For example, the reconstruction algorithm may be an iterative, analytical or other reconstruction algorithm, and the embodiments of the present disclosure do not specifically limit the reconstruction algorithm.

在本公开的一些实施例中,每个分布式射线源20上具有一个或多个靶点,靶点的能量可设定,靶点激活的顺序可设置。例如,靶点可以分布在多个扫描平面上(例如,扫描平面垂直于通道前进方向)。每个平面中,靶点分布可以为连续或不连续的一段或多段直线或弧线。由于靶点能量可设,在出束过程中可以实现不同靶点具有不同能谱,或位于不同平面的靶点能量有区别等多种扫描方式。可以对靶点进行分组设计,比如每个模块的靶点作为一组,或是每个平面的靶点作为一组,同一组内的靶点电子打靶的顺序可调,可以实现顺序出束、交替出束,不同组内的靶点可以同时激活进行扫描,以加快扫描速度。In some embodiments of the present disclosure, each distributed ray source 20 has one or more targets, the energy of the targets can be set, and the order of target activation can be set. For example, the targets can be distributed on multiple scanning planes (for example, the scanning plane is perpendicular to the direction of passage). In each plane, the target distribution can be one or more continuous or discontinuous straight lines or arcs. Since the target energy can be set, a variety of scanning methods can be achieved during the beam emission process, such as different targets having different energy spectra, or targets located in different planes having different energies. The targets can be designed in groups, such as the targets of each module as a group, or the targets of each plane as a group. The order of electronic targeting of the targets in the same group is adjustable, and sequential beam emission and alternating beam emission can be achieved. Targets in different groups can be activated at the same time for scanning to speed up the scanning speed.

探测器30可以是单排或多排,探测器类型可以是单能、双能或者能谱型探测器。The detector 30 may be a single row or multiple rows, and the detector type may be a single energy, dual energy or energy spectrum detector.

传送机构110包括载物台或传输皮带,控制装置140控制X光机及探测器的机架,通过控制分布式射线源的出束方式和被扫描对象的直线平移运动或者两者的组合,可以实现螺旋扫描轨迹或者圆周扫描轨迹或其他特殊轨迹的扫描。控制装置140负责完成CT系统运行过程的控制,包括机械转动、电气控制、安全联锁控制,特别是负责控制射线源的出束速度/频率、出束能量和出束顺序,控制探测器的数据读出与数据重建。The transmission mechanism 110 includes a stage or a transmission belt, and the control device 140 controls the X-ray machine and the detector frame. By controlling the beam emission mode of the distributed radiation source and the linear translation movement of the scanned object or a combination of the two, a spiral scanning track or a circular scanning track or other special tracks can be scanned. The control device 140 is responsible for completing the control of the CT system operation process, including mechanical rotation, electrical control, and safety interlock control, especially responsible for controlling the beam emission speed/frequency, beam emission energy, and beam emission sequence of the radiation source, and controlling the data reading and data reconstruction of the detector.

静态CT得益于其高扫描速度,高稳定性和灵活的扫描方式等优点逐渐成为CT领域的研究热点。但是,作为一个新的技术路线,与原有的螺旋CT在很多数据处理方式上有不同的要求,例如由于多靶点带来的几何校正等问题,不能沿用螺旋CT处理方式。Static CT has gradually become a research hotspot in the field of CT due to its advantages such as high scanning speed, high stability and flexible scanning methods. However, as a new technical route, it has different requirements from the original spiral CT in many data processing methods. For example, due to the geometric correction caused by multiple targets, the spiral CT processing method cannot be used.

根据CT成像理论,如果要对被扫描对象精确CT重建,必须已知射线源靶点和探测器晶体的精确位置,由于机械制作和安装存在误差,因此几何标定成为CT成像中必不可少的步骤。采用分布式射线源或多个单靶点射线源的静态CT,由于射线源本身尺寸较大或数量较多,制作和安装误差也会相应的更大,对成像质量产生较大影响。类似的,探测器也会存在相同的问题,也需要通过几何校正修正几何误差。According to CT imaging theory, if you want to accurately reconstruct the scanned object, you must know the precise position of the radiation source target and the detector crystal. Since there are errors in mechanical manufacturing and installation, geometric calibration becomes an essential step in CT imaging. For static CT using distributed radiation sources or multiple single-target radiation sources, the radiation sources themselves are larger in size or more in number, so the manufacturing and installation errors will be correspondingly larger, which will have a greater impact on the imaging quality. Similarly, the detector will have the same problem, and the geometric error also needs to be corrected through geometric correction.

CT成像理论基于射线衰减符合Beer定律,要求用于扫描成像的探测器具备相同的吸收能谱,这样从不同方向穿过相同厚度的物体射线衰减才可以一致。发明人经研究发现,探测器的吸收能谱和射线入射的晶体厚度相关。在单靶点源探向心的几何排布中,所有射线均为垂直入射晶体,射线穿过的晶体厚度相同,探测器的吸收能谱相同。但是在静态CT设备中,由于单个晶体需要接收不同靶点发出的射线,因此不同靶点射线的入射角度不同,穿过的晶体厚度不同,从而导致吸收能谱不同。另一方面,不同靶点的能谱也可能存在差异。能谱不一致导致的数据不一致性也是影响重建数值准确性的重要因素。CT imaging theory is based on the fact that ray attenuation conforms to Beer's law, which requires that the detectors used for scanning imaging have the same absorption energy spectrum, so that the attenuation of rays passing through objects of the same thickness from different directions can be consistent. The inventors have found through research that the absorption energy spectrum of the detector is related to the thickness of the crystal into which the rays are incident. In the geometric arrangement of a single target source probe centripetal, all rays are vertically incident on the crystal, the crystal thickness through which the rays pass is the same, and the absorption energy spectrum of the detector is the same. However, in static CT equipment, since a single crystal needs to receive rays emitted by different targets, the incident angles of rays from different targets are different, and the crystal thicknesses passed through are different, resulting in different absorption energy spectra. On the other hand, there may also be differences in the energy spectra of different targets. Data inconsistency caused by inconsistent energy spectra is also an important factor affecting the accuracy of reconstructed values.

进一步地,发明还研究发现,不同射线源安装时存在水平面内与高度方向上的差异,会影响CT重建图像的清晰度。由于射线源发出的射线存在与方向相关的能谱空间分布,同时射线在每一个探测器单元的入射角度也不同,导致不同射线的能谱存在差异。在重建过程中,能谱误差会对重建数值产生干扰。Furthermore, the inventors have also found that when different ray sources are installed, there are differences in the horizontal plane and the height direction, which will affect the clarity of the CT reconstructed image. Since the rays emitted by the ray source have a spatial distribution of energy spectra related to the direction, and the incident angles of the rays on each detector unit are also different, the energy spectra of different rays are different. During the reconstruction process, the energy spectrum error will interfere with the reconstructed values.

此外,上述能谱准确性的技术问题,同样也会直接影响单视角/多视角X射线成像设备的图像颜色准确性,并间接影响一些嫌疑物品自动识别的准确性。In addition, the above-mentioned technical problems of energy spectrum accuracy will also directly affect the image color accuracy of single-view/multi-view X-ray imaging equipment, and indirectly affect the accuracy of automatic identification of some suspicious objects.

本公开的实施例提供了一种用于标定扫描成像设备的标定方法和标定系统,它可以对扫描成像设备进行几何标定和能谱标定,例如,可以对基于分布式射线源的静态CT设备进行几何标定和能谱标定。The embodiments of the present disclosure provide a calibration method and a calibration system for calibrating a scanning imaging device, which can perform geometric calibration and energy spectrum calibration on the scanning imaging device, for example, can perform geometric calibration and energy spectrum calibration on a static CT device based on a distributed ray source.

图4A是根据本公开的一些示例性实施例的标定系统的结构示意图。图4B是从另一角度观察的根据本公开的一些示例性实施例的标定系统的结构示意图。图4C是根据本公开的一些示例性实施例的标定系统的结构示意图,其示意性示出了一个金属丝。图4D是图4C所示的标定系统的侧视图。图4E是根据本公开的一些示例性实施例的标定系统的结构示意图,其示意性示出了多个金属丝。FIG. 4A is a schematic diagram of the structure of a calibration system according to some exemplary embodiments of the present disclosure. FIG. 4B is a schematic diagram of the structure of a calibration system according to some exemplary embodiments of the present disclosure observed from another angle. FIG. 4C is a schematic diagram of the structure of a calibration system according to some exemplary embodiments of the present disclosure, schematically showing a metal wire. FIG. 4D is a side view of the calibration system shown in FIG. 4C. FIG. 4E is a schematic diagram of the structure of a calibration system according to some exemplary embodiments of the present disclosure, schematically showing multiple metal wires.

参照图4A和图4B,所述标定系统40可以包括:底座410;连接于底座410上的旋转台420;设置于旋转台420上的几何标定模体50和能谱标定模体60中的至少一个;以及驱动件430,驱动件430用于驱动旋转台420旋转,以带动几何标定模体50和能谱标定模体60中的至少一个旋转。4A and 4B , the calibration system 40 may include: a base 410; a rotating table 420 connected to the base 410; at least one of a geometric calibration phantom 50 and an energy spectrum calibration phantom 60 disposed on the rotating table 420; and a driving member 430, the driving member 430 being used to drive the rotating table 420 to rotate, so as to drive at least one of the geometric calibration phantom 50 and the energy spectrum calibration phantom 60 to rotate.

例如,在图4A和图4B所示的实施例中,几何标定模体50和能谱标定模体60均设置于旋转台420上。在本公开的其他实施例中,可以是几何标定模体50和能谱标定模体60中的一个设置于旋转台420上。例如,在图4C~图4E所示的实施例中,仅几何标定模体50设置于旋转台420上。For example, in the embodiments shown in FIGS. 4A and 4B , both the geometric calibration phantom 50 and the energy spectrum calibration phantom 60 are disposed on the rotating table 420. In other embodiments of the present disclosure, one of the geometric calibration phantom 50 and the energy spectrum calibration phantom 60 may be disposed on the rotating table 420. For example, in the embodiments shown in FIGS. 4C to 4E , only the geometric calibration phantom 50 is disposed on the rotating table 420.

在一些示例性实施例中,所述几何标定模体50可以包括至少一个金属丝。例如,几何标定模体50包括仅一个金属丝,该一个金属丝位于旋转台420的离心位置。In some exemplary embodiments, the geometric calibration phantom 50 may include at least one metal wire. For example, the geometric calibration phantom 50 includes only one metal wire, and the one metal wire is located at an eccentric position of the rotating stage 420 .

参照图4A和图4B,旋转台420围绕旋转轴线AX1旋转。一个金属丝垂直设置在旋转台420上且距离旋转轴线AX1一定的偏移距离。由于几何标定模体在旋转台420上的离心设置,所以,在旋转台420旋转过程中,几何标定模体可以处于不同的几何位置,有利于从多个不同的几何位置获取标定数据,从而可以提高标定的精度。4A and 4B , the rotating table 420 rotates around the rotation axis AX1. A metal wire is vertically arranged on the rotating table 420 and is offset from the rotation axis AX1. Due to the centrifugal arrangement of the geometric calibration phantom on the rotating table 420, the geometric calibration phantom can be in different geometric positions during the rotation of the rotating table 420, which is conducive to obtaining calibration data from multiple different geometric positions, thereby improving the accuracy of calibration.

参照图4E,旋转台420围绕旋转轴线AX1旋转。所述几何标定模体50可以包括多个金属丝,多个金属丝分别位于旋转台420的不同离心位置,即,多个金属丝以彼此不同的半径和/或彼此不同的角度分布在旋转台420上。也就是说,在旋转台420上,所述多个金属丝中任一个金属丝的半径和角度中的至少一个与所述多个金属丝中另一个金属丝的半径和角度中的至少一个不相同。4E , the rotating stage 420 rotates around the rotation axis AX1. The geometric calibration phantom 50 may include a plurality of metal wires, which are respectively located at different centrifugal positions of the rotating stage 420, that is, the plurality of metal wires are distributed on the rotating stage 420 at different radii and/or different angles. That is, on the rotating stage 420, at least one of the radius and angle of any one of the plurality of metal wires is different from at least one of the radius and angle of another of the plurality of metal wires.

例如,在图4E所示的实施例中,示意性示出了四个金属丝,为了描述方便,分别标记为第一金属丝501、第二金属丝502、第三金属丝503和第四金属丝504。第一金属丝501、第二金属丝502、第三金属丝503和第四金属丝504均垂直设置在旋转台420上,且距离旋转轴线AX1的偏移距离分别为ρ1、ρ2、ρ3、ρ4For example, in the embodiment shown in Fig. 4E, four metal wires are schematically shown, which, for the convenience of description, are respectively labeled as a first metal wire 501, a second metal wire 502, a third metal wire 503, and a fourth metal wire 504. The first metal wire 501, the second metal wire 502, the third metal wire 503, and the fourth metal wire 504 are all vertically arranged on the rotating stage 420, and the offset distances from the rotating axis AX1 are ρ1 , ρ2 , ρ3 , ρ4 , respectively.

图4F为图4E中所示的四个金属丝在旋转台上的投影图。参照图4E和图4F,建立一个极坐标系,在该极坐标系中,以旋转轴线AX1在旋转台420上的正投影的点作为极点AXO,由极点AXO出发的一条射线OX作为极轴。在此基础上,四个金属丝的位置可以通过(ρ,θ)表示,其中,ρ对应极坐标系中的极径、矢径或半径,具体为金属丝在旋转台上的正投影的点相对于极点AXO的距离;θ对应极坐标系中的极角或辐角,具体为金属丝在旋转台上的正投影的点与极点的连线相对于极轴OX的角度。FIG4F is a projection diagram of the four metal wires shown in FIG4E on the rotating table. Referring to FIG4E and FIG4F, a polar coordinate system is established, in which the point of the orthographic projection of the rotation axis AX1 on the rotating table 420 is taken as the pole AXO, and a ray OX starting from the pole AXO is taken as the polar axis. On this basis, the positions of the four metal wires can be represented by (ρ, θ), wherein ρ corresponds to the polar diameter, vector radius or radius in the polar coordinate system, specifically the distance of the point of the orthographic projection of the metal wire on the rotating table relative to the pole AXO; θ corresponds to the polar angle or radian in the polar coordinate system, specifically the angle of the line connecting the point of the orthographic projection of the metal wire on the rotating table and the pole relative to the polar axis OX.

示例性地,第一金属丝501、第二金属丝502、第三金属丝503和第四金属丝504的位置分别表示为(ρ1,θ1)、(ρ2,θ2)、(ρ3,θ3)、(ρ4,θ4)。ρ1、ρ2、ρ3、ρ4中的任意两者不相等,和/或,θ1、θ2、θ3、θ4中的任意两者不相等。Exemplarily, the positions of the first metal wire 501, the second metal wire 502, the third metal wire 503 and the fourth metal wire 504 are respectively expressed as (ρ 1 , θ 1 ), (ρ 2 , θ 2 ), (ρ 3 , θ 3 ), (ρ 4 , θ 4 ). Any two of ρ 1 , ρ 2 , ρ 3 , ρ 4 are not equal, and/or any two of θ 1 , θ 2 , θ 3 , θ 4 are not equal.

在该实施例中,多个金属丝设置在旋转台420上且距离旋转轴线AX1不同的偏移距离或偏移角度,这样,在旋转台420旋转过程中,多个金属丝可以处于不同的几何位置,有利于从多个不同的几何位置获取标定数据,从而可以进一步提高标定的精度。In this embodiment, multiple metal wires are arranged on the rotating table 420 and have different offset distances or offset angles from the rotation axis AX1. In this way, during the rotation of the rotating table 420, the multiple metal wires can be in different geometric positions, which is conducive to obtaining calibration data from multiple different geometric positions, thereby further improving the calibration accuracy.

在一些示例性实施例中,所述金属丝可以为硬质金属丝,这样,金属丝可以垂直于旋转台420的台面,有利于将金属丝的前端设置在扫描区域中。In some exemplary embodiments, the metal wire may be a hard metal wire, so that the metal wire may be perpendicular to the table surface of the rotating table 420 , which is beneficial for placing the front end of the metal wire in the scanning area.

在一些示例性实施例中,所述金属丝的直径不大于单个探测器晶体的宽度。通过将金属丝的直径设计得较小,可以提高标定的精度。In some exemplary embodiments, the diameter of the metal wire is no greater than the width of a single detector crystal. By designing the diameter of the metal wire to be smaller, the accuracy of calibration can be improved.

在一些示例性实施例中,能谱标定模体60位于旋转台420的中心位置。例如,能谱标定模体60的几何中心位于旋转台420的旋转轴线AX1上。In some exemplary embodiments, the energy spectrum calibration phantom 60 is located at the center of the rotating stage 420. For example, the geometric center of the energy spectrum calibration phantom 60 is located on the rotation axis AX1 of the rotating stage 420.

在一些示例性实施例中,所述能谱标定模体60可以包括分别由多种材料构成的多个部分,所述多种材料中的任意两者的以下至少一种属性不相同:密度,原子序数。In some exemplary embodiments, the energy spectrum calibration phantom 60 may include a plurality of parts respectively made of a plurality of materials, and at least one of the following properties of any two of the plurality of materials is different: density, atomic number.

在一些示例性实施例中,能谱标定模体60可以为具有足够衰减能力的已知材料或未知材料组成的具有一定形状的物体。例如,能谱标定模体60的材料可以选择石墨、有机玻璃、聚乙烯、聚甲醛、铝(合金)、镁(合金)、二氧化硅、聚氯乙烯、钛(合金)、铁、铜等。这些材料的化学成分和物理密度等属性为已知信息。又例如,能谱标定模体60的材料也可以选择一些物理化学性质稳定的材料,但材料的成分比例信息无法准确获得的材料。In some exemplary embodiments, the energy spectrum calibration model 60 can be an object with a certain shape composed of a known material or an unknown material with sufficient attenuation capability. For example, the material of the energy spectrum calibration model 60 can be selected from graphite, organic glass, polyethylene, polyoxymethylene, aluminum (alloy), magnesium (alloy), silicon dioxide, polyvinyl chloride, titanium (alloy), iron, copper, etc. The chemical composition and physical density and other properties of these materials are known information. For another example, the material of the energy spectrum calibration model 60 can also be selected from some materials with stable physical and chemical properties, but the composition ratio information of the material cannot be accurately obtained.

在一些示例性实施例中,能谱标定模体60的材料的原子序数范围应尽量覆盖较宽的范围。In some exemplary embodiments, the atomic number range of the material of the energy spectrum calibration phantom 60 should cover a wider range as possible.

能谱标定模体60的形状可以为圆柱、棱柱、棱锥,也可以为不规则形状。在标定过程中,射线与能谱标定模体60相交的交线长度应尽量覆盖较宽的范围。The shape of the energy spectrum calibration phantom 60 can be a cylinder, a prism, a pyramid, or an irregular shape. During the calibration process, the length of the intersection line between the ray and the energy spectrum calibration phantom 60 should cover a wide range as much as possible.

需要说明的是,在图4A和图4B所示的实施例中,能谱标定模体60的形状为长方体,但是,该形状仅是示例性的,不是对本公开实施例的限制。在本公开的其他实施例中,能谱标定模体60可以采用任何其他合适的形状。It should be noted that in the embodiments shown in FIG. 4A and FIG. 4B , the shape of the energy spectrum calibration phantom 60 is a rectangular parallelepiped, but this shape is only exemplary and is not a limitation to the embodiments of the present disclosure. In other embodiments of the present disclosure, the energy spectrum calibration phantom 60 may adopt any other suitable shape.

继续参照图4A和图4B,标定系统40还可以包括:升降台440,升降台440连接于底座410上,旋转台420设置于升降台440上。这样,可以通过控制升降台上下平移固定距离,在多个高度位置扫描金属丝以获得更多的标定数据,从而有利于提高标定精度。4A and 4B , the calibration system 40 may further include a lifting platform 440, the lifting platform 440 is connected to the base 410, and the rotating platform 420 is disposed on the lifting platform 440. In this way, the metal wire can be scanned at multiple height positions to obtain more calibration data by controlling the lifting platform to translate up and down a fixed distance, thereby facilitating improving the calibration accuracy.

在本公开的实施例中,底座410用于承载其他部件,并保持设置在其上的部件的稳定性。驱动件430可以包括用于驱动升降台440上下移动的移动驱动机构;和/或,用于驱动旋转台420旋转的旋转驱动机构。In the embodiment of the present disclosure, the base 410 is used to carry other components and maintain the stability of the components arranged thereon. The driving member 430 may include a moving driving mechanism for driving the lifting platform 440 to move up and down; and/or a rotating driving mechanism for driving the rotating platform 420 to rotate.

例如,用于驱动旋转台420旋转的旋转驱动机构可以包括齿轮传动机构、伺服电机驱动机构和步进电机驱动机构中的至少一种。齿轮传动机构可以包括驱动电机、驱动齿轮和被驱动齿轮组成,通过齿轮的啮合实现旋转力传递。伺服电机驱动是通过控制伺服电机的转速和位置来实现旋转台的旋转。伺服电机通常与编码器和闭环控制系统结合使用,以实现高精度的旋转控制。步进电机驱动通过控制步进电机的脉冲信号来实现旋转台的旋转。步进电机具有离散的步进角度,可以精确控制旋转台的位置和速度。For example, the rotation drive mechanism for driving the rotating table 420 to rotate may include at least one of a gear transmission mechanism, a servo motor drive mechanism and a stepper motor drive mechanism. The gear transmission mechanism may include a driving motor, a driving gear and a driven gear, and the rotational force transmission is realized by the meshing of the gears. The servo motor drive is to realize the rotation of the rotating table by controlling the speed and position of the servo motor. The servo motor is usually used in combination with an encoder and a closed-loop control system to achieve high-precision rotation control. The stepper motor drive realizes the rotation of the rotating table by controlling the pulse signal of the stepper motor. The stepper motor has a discrete step angle, which can accurately control the position and speed of the rotating table.

例如,用于驱动升降台440上下移动的移动驱动机构可以包括螺杆传动机构、电动螺杆传动机构和齿轮传动机构中的至少一种。螺杆传动机构可以包括螺杆和与之啮合的螺母。当螺杆旋转时,螺母沿着螺杆的螺旋线移动,从而实现升降台的上下移动。电动螺杆传动机构结合了螺杆传动和电动驱动技术。通过电动机驱动螺杆旋转,从而推动升降台进行上下移动。齿轮传动机构使用齿轮的啮合来传递力和运动。通过驱动齿轮的旋转,可以实现升降台的上下移动。For example, the mobile drive mechanism for driving the lifting platform 440 to move up and down may include at least one of a screw drive mechanism, an electric screw drive mechanism, and a gear drive mechanism. The screw drive mechanism may include a screw and a nut meshing therewith. When the screw rotates, the nut moves along the spiral line of the screw, thereby realizing the up and down movement of the lifting platform. The electric screw drive mechanism combines screw drive and electric drive technology. The screw is driven to rotate by an electric motor, thereby pushing the lifting platform to move up and down. The gear drive mechanism uses the meshing of gears to transmit force and motion. By driving the rotation of the gear, the up and down movement of the lifting platform can be realized.

需要说明的是,在本公开的实施例中,不对旋转驱动机构、移动驱动机构的类型和结构做特别的限制,在不冲突的情况下,相关领域中已知的各种类型的旋转驱动机构、移动驱动机构均可以用于本公开的实施例中。It should be noted that in the embodiments of the present disclosure, there is no particular restriction on the type and structure of the rotary drive mechanism and the mobile drive mechanism. In the absence of conflict, various types of rotary drive mechanisms and mobile drive mechanisms known in the relevant field can be used in the embodiments of the present disclosure.

本公开的一些示例性实施例还提供一种用于标定扫描成像设备的标定方法,其适于对扫描成像设备进行几何标定和能谱标定。Some exemplary embodiments of the present disclosure also provide a calibration method for calibrating a scanning imaging device, which is suitable for performing geometric calibration and energy spectrum calibration on the scanning imaging device.

在根据本公开的一些实施例的标定方法中,可以先执行几何标定,后执行能谱标定。图5是根据本公开的一些示例性实施例的标定方法的流程图。在该实施例的标定过程中,几何标定模体或能谱标定模体位于所述射线形成的扫描区域中,也就是说,仅几何标定模体和能谱标定模体中的一者位于所述扫描区域中。例如,所述标定方法可以包括步骤S510~S530。In the calibration method according to some embodiments of the present disclosure, geometric calibration may be performed first, and then energy spectrum calibration may be performed. FIG5 is a flow chart of a calibration method according to some exemplary embodiments of the present disclosure. In the calibration process of this embodiment, a geometric calibration phantom or an energy spectrum calibration phantom is located in the scanning area formed by the rays, that is, only one of the geometric calibration phantom and the energy spectrum calibration phantom is located in the scanning area. For example, the calibration method may include steps S510 to S530.

在步骤S510中,在几何标定模体位于所述射线形成的扫描区域中的情况下,执行几何标定步骤,其中,所述几何标定步骤包括:通过所述探测器采集经过所述扫描区域的射线,获得与所述几何标定模体相关的探测器数据;利用所述探测器数据,对射线源参数和探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,并将所述优化的射线源参数和优化的探测器参数确定为几何标定参数,其中,所述射线源参数用于表示所述射线源在标定系统中的位置,所述探测器参数用于表示所述探测器在所述标定系统中的位置。In step S510, when the geometric calibration phantom is located in the scanning area formed by the rays, a geometric calibration step is performed, wherein the geometric calibration step includes: collecting rays passing through the scanning area by the detector to obtain detector data related to the geometric calibration phantom; using the detector data, calibrating ray source parameters and detector parameters to obtain optimized ray source parameters and optimized detector parameters, and determining the optimized ray source parameters and optimized detector parameters as geometric calibration parameters, wherein the ray source parameters are used to represent the position of the ray source in the calibration system, and the detector parameters are used to represent the position of the detector in the calibration system.

在步骤S520中,在能谱标定模体位于所述射线形成的扫描区域中的情况下,根据所述几何标定参数,确定所述射线源、所述能谱标定模体和所述探测器之间的相对位置,以获取所述射线源、所述能谱标定模体和所述探测器之间的几何关系。In step S520, when the energy spectrum calibration phantom is located in the scanning area formed by the rays, the relative positions among the ray source, the energy spectrum calibration phantom and the detector are determined according to the geometric calibration parameters to obtain the geometric relationship among the ray source, the energy spectrum calibration phantom and the detector.

在步骤S530中,在能谱标定模体位于所述射线形成的扫描区域中的情况下,执行能谱标定步骤,其中,所述能谱标定步骤包括:通过所述探测器采集经过所述扫描区域的射线,获取与所述能谱模体相关的实际投影数据;利用与所述能谱模体相关的实际投影数据,根据所述几何关系和所述能谱标定模体的物理属性,对能谱参数进行标定,以获取优化的能谱参数,并将所述优化的能谱参数确定为能谱标定参数。In step S530, when the energy spectrum calibration phantom is located in the scanning area formed by the rays, an energy spectrum calibration step is performed, wherein the energy spectrum calibration step includes: collecting the rays passing through the scanning area by the detector to obtain actual projection data related to the energy spectrum phantom; using the actual projection data related to the energy spectrum phantom, according to the geometric relationship and the physical properties of the energy spectrum calibration phantom, calibrating the energy spectrum parameters to obtain optimized energy spectrum parameters, and determining the optimized energy spectrum parameters as energy spectrum calibration parameters.

在根据本公开的另一些实施例的标定方法中,可以同时执行几何标定和能谱标定。图6是根据本公开的一些示例性实施例的标定方法的流程图。在该实施例的标定过程中,几何标定模体和能谱标定模体两者均位于所述射线形成的扫描区域中。所述标定方法包括:在几何标定模体和能谱标定模体两者均位于所述射线形成的扫描区域中的情况下,执行几何标定步骤和能谱标定步骤。例如,所述标定方法可以具体包括步骤S610~S640。In the calibration method according to some other embodiments of the present disclosure, geometric calibration and energy spectrum calibration can be performed simultaneously. Figure 6 is a flow chart of the calibration method according to some exemplary embodiments of the present disclosure. In the calibration process of this embodiment, both the geometric calibration phantom and the energy spectrum calibration phantom are located in the scanning area formed by the rays. The calibration method includes: when both the geometric calibration phantom and the energy spectrum calibration phantom are located in the scanning area formed by the rays, performing a geometric calibration step and an energy spectrum calibration step. For example, the calibration method may specifically include steps S610 to S640.

在步骤S610中,通过所述探测器采集经过所述扫描区域的射线,获取与所述几何标定模体和所述能谱标定模体均相关的探测器数据。In step S610, the detector collects rays passing through the scanning area to obtain detector data related to both the geometric calibration phantom and the energy spectrum calibration phantom.

在步骤S620中,利用所述探测器数据,对射线源参数和探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,并将所述优化的射线源参数和优化的探测器参数确定为几何标定参数,其中,所述射线源参数用于表示所述射线源在标定系统中的位置,所述探测器参数用于表示所述探测器在所述标定系统中的位置。In step S620, the detector data is used to calibrate the ray source parameters and the detector parameters to obtain optimized ray source parameters and optimized detector parameters, and the optimized ray source parameters and optimized detector parameters are determined as geometric calibration parameters, wherein the ray source parameters are used to represent the position of the ray source in the calibration system, and the detector parameters are used to represent the position of the detector in the calibration system.

在步骤S630中,根据所述几何标定参数,确定所述射线源、所述能谱标定模体和所述探测器之间的相对位置,以获取所述射线源、所述能谱标定模体和所述探测器之间的几何关系。In step S630, the relative positions among the ray source, the energy spectrum calibration phantom and the detector are determined according to the geometric calibration parameters to obtain the geometric relationship among the ray source, the energy spectrum calibration phantom and the detector.

在步骤S640中,利用所述探测器数据,根据所述几何关系和所述能谱标定模体的物理属性,对能谱参数进行标定,以获取优化的能谱参数,并将所述优化的能谱参数确定为能谱标定参数。In step S640, the energy spectrum parameters are calibrated using the detector data according to the geometric relationship and the physical properties of the energy spectrum calibration phantom to obtain optimized energy spectrum parameters, and the optimized energy spectrum parameters are determined as energy spectrum calibration parameters.

需要说明的是,除非另有特别说明或在有冲突的情况下,在下文中描述的步骤或方法可以适用于上文描述的各个实施例中。具体地,在没有特别说明的情况下,下面描述的各个步骤可以适用于上文中针对图5和图6描述的标定方法两者中。It should be noted that, unless otherwise specified or in case of conflict, the steps or methods described below can be applied to the various embodiments described above. Specifically, unless otherwise specified, the various steps described below can be applied to both the calibration methods described above for FIG. 5 and FIG. 6.

下面,首先结合附图,描述执行几何标定的步骤的详细实施方式。Below, firstly, a detailed implementation of the steps of performing geometric calibration is described in conjunction with the accompanying drawings.

图4D是图4C所示的标定系统的侧视图。结合参照图4A至图4D,在进行标定时,标定系统40放置在扫描成像设备的传送装置(例如图2所示的传送机构110)上,控制传送装置将标定系统40的几何标定装模体50输送到X射线的扫描平面,使得几何标定模体50处于射线源20和探测器30组成的扫描平面内。例如,在进行几何标定时,仅几何标定模体50的前端位于扫描平面内,标定系统40的其他部分始终处于扫描平面以外。这样,可以避免标定系统40的其他部分对标定数据造成干扰。FIG4D is a side view of the calibration system shown in FIG4C. Referring to FIG4A to FIG4D , when performing calibration, the calibration system 40 is placed on a conveying device (e.g., the conveying mechanism 110 shown in FIG2 ) of the scanning imaging device, and the conveying device is controlled to transport the geometric calibration phantom 50 of the calibration system 40 to the X-ray scanning plane, so that the geometric calibration phantom 50 is in the scanning plane formed by the ray source 20 and the detector 30. For example, when performing geometric calibration, only the front end of the geometric calibration phantom 50 is located in the scanning plane, and the other parts of the calibration system 40 are always outside the scanning plane. In this way, it is possible to avoid interference of other parts of the calibration system 40 with the calibration data.

图7是根据本公开的一些示例性实施例的标定方法中的几何标定步骤的流程图。结合参照图1至图7,所述标定方法可以用于对扫描成像设备进行几何标定,例如,该标定方法可以对静态CT设备进行几何标定。在该静态CT设备中,射线源20可以为分布式射线源,其包括Ns个靶点210,Ns个靶点沿第一方向间隔分布,其中,Ns为大于等于2的正整数。所述第一方向可以对应图3A所示的直线排列方向或图3B所示的弧线排列方法。需要说明的是,本公开的实施例中,不对分布式射线源的多个靶点的排列方向和形式做特别的限制。FIG. 7 is a flow chart of the geometric calibration steps in the calibration method according to some exemplary embodiments of the present disclosure. With reference to FIGS. 1 to 7 , the calibration method can be used to perform geometric calibration on a scanning imaging device. For example, the calibration method can perform geometric calibration on a static CT device. In the static CT device, the ray source 20 can be a distributed ray source, which includes N s target points 210, and the N s target points are spaced apart along a first direction, wherein N s is a positive integer greater than or equal to 2. The first direction can correspond to the straight line arrangement direction shown in FIG. 3A or the arc arrangement method shown in FIG. 3B. It should be noted that in the embodiments of the present disclosure, no special restrictions are imposed on the arrangement direction and form of the multiple target points of the distributed ray source.

在本公开的一些实施例中,所述标定方法的几何标定步骤可以包括子步骤S710~S750。In some embodiments of the present disclosure, the geometric calibration step of the calibration method may include sub-steps S710 to S750.

在子步骤S710中,通过探测器30采集经过扫描区域的射线,获得探测器数据,其中,探测器数据包括射线经过扫描区域后在探测器30上的实际投影位置。In sub-step S710, the detector 30 collects the rays passing through the scanning area to obtain detector data, wherein the detector data includes the actual projection position of the rays on the detector 30 after passing through the scanning area.

在一些示例性的实施例中,所述标定方法可以包括:在将几何标定模体50置于射线形成的扫描区域或扫描平面之前,通过探测器30采集空气投影数据pairIn some exemplary embodiments, the calibration method may include: before placing the geometric calibration phantom 50 in a scanning area or a scanning plane formed by rays, collecting air projection data p air by the detector 30 .

应该理解,在进行图像重建时,需要知道探测器在没有物体(即只有空气)的情况下的读数,以便从实际的测量数据中去除这个背景值。例如,在CT成像中,例如,通常会使用一种称为线积分的方法来获取投影数据。这个过程涉及到将射线通过物体,并测量射线在穿过物体后的衰减。这个衰减值(或者说投影数据)就反映了射线路径上物质的性质,例如密度和组成。在没有物体存在,也就是只有空气的情况下,也可以进行类似的测量。这样得到的投影数据就可以作为一个参考或者说是背景值,在实际的图像重建过程中,从测量到的投影数据中去除这个背景值,以得到只由物体本身造成的射线衰减。It should be understood that when performing image reconstruction, it is necessary to know the detector reading in the absence of an object (i.e., only air) in order to remove this background value from the actual measured data. For example, in CT imaging, a method called line integral is often used to obtain projection data. This process involves passing rays through an object and measuring the attenuation of the rays after passing through the object. This attenuation value (or projection data) reflects the properties of the material in the ray path, such as density and composition. Similar measurements can be made in the absence of an object, that is, only air. The projection data thus obtained can be used as a reference or background value, and in the actual image reconstruction process, this background value is removed from the measured projection data to obtain the ray attenuation caused only by the object itself.

在子步骤S710中,所述获得探测器数据包括:通过探测器30采集经过扫描区域(几何标定模体50位于该扫描区域中)的射线,获得初始探测器数据pi;以及,利用空气投影数据pair,对初始探测器数据pi进行校正,以获得探测器数据prjiIn sub-step S710, obtaining detector data includes: acquiring rays passing through a scanning area (where the geometric calibration phantom 50 is located) through the detector 30 to obtain initial detector data pi ; and correcting the initial detector data pi using air projection data p air to obtain detector data prj i .

需要说明的是,在本文中,1≤i≤Ns,即,i表示的分布式射线源中某一个靶点210的编号。It should be noted that, in this article, 1≤i≤N s , that is, i represents the number of a target point 210 in the distributed ray source.

例如,可以利用以下的公式来进行空气校正,以获得探测器数据prji:prji=pi/pairFor example, the following formula may be used to perform air correction to obtain the detector data prj i : prj i = p i / p air .

在本公开的一些示例性的实施例中,标定系统40包括旋转台420,几何标定模体50位于旋转台420上。In some exemplary embodiments of the present disclosure, the calibration system 40 includes a rotating stage 420 , and the geometric calibration phantom 50 is located on the rotating stage 420 .

在该实施例中,获得初始探测器数据pi可以包括:控制射线源20发出射线;控制旋转台420旋转,以带动几何标定模体50旋转m圈,其中,m为大于等于1的正整数;以及,在几何标定模体50旋转m圈的过程中,探测器30采集从射线源20发出且经过扫描区域的射线。In this embodiment, obtaining the initial detector data p i may include: controlling the ray source 20 to emit rays; controlling the rotating table 420 to rotate to drive the geometric calibration phantom 50 to rotate m circles, where m is a positive integer greater than or equal to 1; and, during the process of the geometric calibration phantom 50 rotating m circles, the detector 30 collects rays emitted from the ray source 20 and passing through the scanning area.

在本公开的一些示例性的实施例中,标定系统40包括升降台440,几何标定模体50位于升降台440上。In some exemplary embodiments of the present disclosure, the calibration system 40 includes a lifting platform 440 , and the geometric calibration phantom 50 is located on the lifting platform 440 .

在该实施例中,获得初始探测器数据pi可以包括:控制射线源20发出射线;控制升降台440升降,以带动几何标定模体50升降。In this embodiment, obtaining the initial detector data p i may include: controlling the ray source 20 to emit rays; and controlling the lifting platform 440 to move up and down, so as to drive the geometric calibration phantom 50 to move up and down.

例如,通过升降台440的升降运动,可以带动几何标定模体50上升至扫描位置。在升降过程中,探测器可以不采集数据。For example, the geometric calibration phantom 50 may be driven to rise to the scanning position by the lifting and lowering motion of the lifting platform 440. During the lifting and lowering process, the detector may not collect data.

再例如,在几何标定模体50升降过程中,探测器30可以采集从射线源20发出且经过扫描区域的射线。在一些可选的实施例中,在升降过程中采集的数据可以不用于后续的处理。For another example, during the lifting process of the geometric calibration phantom 50, the detector 30 may collect radiation emitted from the radiation source 20 and passing through the scanning area. In some optional embodiments, the data collected during the lifting process may not be used for subsequent processing.

在本公开的一些示例性的实施例中,射线源20包括Ns个靶点210,Ns个靶点210沿第一方向间隔分布,其中,Ns为大于等于2的正整数。In some exemplary embodiments of the present disclosure, the ray source 20 includes N s target points 210 , and the N s target points 210 are spaced apart along the first direction, where N s is a positive integer greater than or equal to 2.

在该实施例中,获得初始探测器数据pi可以包括:控制Ns个靶点210按照设定顺序发出射线;以及在Ns个靶点210按照设定顺序发出射线的过程中,探测器30采集从射线源20发出且经过扫描区域的射线。In this embodiment, obtaining the initial detector data pi may include: controlling the Ns target points 210 to emit radiation in a set order; and in the process of the Ns target points 210 emitting radiation in the set order, the detector 30 collects radiation emitted from the radiation source 20 and passing through the scanning area.

在本公开的一些示例性的实施例中,标定系统40包括旋转台420,几何标定模体50位于旋转台420上。射线源20包括Ns个靶点210,Ns个靶点210沿第一方向间隔分布,其中,Ns为大于等于2的正整数。In some exemplary embodiments of the present disclosure, the calibration system 40 includes a rotating table 420, and the geometric calibration phantom 50 is located on the rotating table 420. The radiation source 20 includes Ns target points 210, and the Ns target points 210 are spaced apart along the first direction, where Ns is a positive integer greater than or equal to 2.

在该实施例中,获得初始探测器数据pi可以包括:控制Ns个靶点210按照设定顺序发出射线;控制旋转台420旋转,以带动几何标定模体50旋转m圈,其中,m为大于等于1的正整数;以及在Ns个靶点210按照设定顺序发出射线和几何标定模体50旋转m圈的过程中,探测器30采集从射线源发出且经过扫描区域的射线。In this embodiment, obtaining the initial detector data p i may include: controlling the N s target points 210 to emit rays in a set order; controlling the rotating table 420 to rotate to drive the geometric calibration model 50 to rotate m circles, where m is a positive integer greater than or equal to 1; and in the process of the N s target points 210 emitting rays in a set order and the geometric calibration model 50 rotating m circles, the detector 30 collects rays emitted from the ray source and passing through the scanning area.

需要说明的是,在本公开的实施例中,对几何标定模体的运动形式、设置数量和射线源的靶点数量不做特别的限制,在不冲突的情况下,各种情况可以相互组合和结合。例如,在一些实施例中,几何标定模体50可以设置在旋转台上,旋转台设置在升降台上,射线源20可以为包括多个靶点的分布式射线源,这样,获得探测器数据prji的步骤可以根据该设置方式进行相应调整,在此不再赘述。It should be noted that in the embodiments of the present disclosure, there is no particular restriction on the movement form, setting number and target number of the geometric calibration phantom, and various situations can be combined and combined with each other without conflict. For example, in some embodiments, the geometric calibration phantom 50 can be set on a rotating table, the rotating table is set on a lifting table, and the ray source 20 can be a distributed ray source including multiple target points. In this way, the step of obtaining the detector data prj i can be adjusted accordingly according to the setting mode, which will not be repeated here.

还需要说明的是,在本公开的实施例中,几何标定模体50的运动和射线源的出束的顺序可以不做特别限制。例如,几何标定模体50固定于一个位置,控制所有靶点按照设定顺序出一次束,然后旋转台旋转至下一个位置,控制所有靶点再次出束,直至旋转台旋转一周后结束。It should also be noted that in the embodiments of the present disclosure, the movement of the geometric calibration phantom 50 and the order of the beam emission of the radiation source may not be particularly limited. For example, the geometric calibration phantom 50 is fixed at one position, and all the targets are controlled to emit beams once in a set order, and then the rotating stage rotates to the next position, and all the targets are controlled to emit beams again, until the rotating stage rotates one circle and ends.

在子步骤S720中,获取初始的射线源参数和初始的探测器参数,其中,射线源参数用于表示射线源20在标定系统40中的位置,探测器参数用于表示探测器30在标定系统40中的位置。In sub-step S720 , initial ray source parameters and initial detector parameters are acquired, wherein the ray source parameters are used to indicate the position of the ray source 20 in the calibration system 40 , and the detector parameters are used to indicate the position of the detector 30 in the calibration system 40 .

发明人经研究发现,在利用分布式射线源的静态CT扫描成像设备中,由于靶点距离间隔较大,尤其是由多个单靶点组合而成的射线源,每个靶点的误差不一致。探测器晶体密集排布,误差相对较小,误差主要来源于整个探测器臂架的安装。因此,几何标定对于每个靶点位置进行单独标定,对探测器按照整个探测器臂架进行标定。The inventor has found through research that in a static CT scanning imaging device using a distributed radiation source, due to the large distance between the targets, especially the radiation source composed of multiple single targets, the error of each target is inconsistent. The detector crystals are densely arranged, and the error is relatively small. The error mainly comes from the installation of the entire detector arm. Therefore, the geometric calibration calibrates each target position separately, and the detector is calibrated according to the entire detector arm.

在本文中,为了描述方便,将射线源参数描述为si,将探测器参数描述为PdIn this paper, for the convenience of description, the ray source parameters are described as s i and the detector parameters are described as P d .

在一些示例性的实施例中,射线源采用分布式射线源,靶点间隔具备足够高的精度,误差主要来源于射线源整体的安装,则可以对靶点位置进行整体标定,即{si:1≤i≤Ns}由分布式射线源的起始坐标、排布方向和编号i决定。在该实施例中,所述射线源中相邻两个靶点的相对位置关系已知,射线源参数si可以包括:Ns个靶点中第1个靶点在标定系统中的位置坐标,Ns个靶点的排列方向,和Ns个靶点中各个靶点的编号。In some exemplary embodiments, the ray source adopts a distributed ray source, the target point interval has a sufficiently high accuracy, and the error mainly comes from the overall installation of the ray source, then the target point position can be calibrated as a whole, that is, {s i : 1≤i≤N s } is determined by the starting coordinates, arrangement direction and number i of the distributed ray source. In this embodiment, the relative position relationship between two adjacent target points in the ray source is known, and the ray source parameter si may include: the position coordinates of the first target point among the N s target points in the calibration system, the arrangement direction of the N s target points, and the number of each target point among the N s target points.

在一些示例性的实施案例中,探测器臂采用直线排布或弧线排列,探测器臂的参数为起始坐标和排布方向。In some exemplary implementation cases, the detector arms are arranged in a straight line or an arc, and the parameters of the detector arms are a starting coordinate and an arrangement direction.

例如,参照图4A至图4D,探测器30可以包括探测器臂320和安装于探测器臂320上的多个探测单元310。多个探测单元310在探测器臂320上直线排列。在该实施例中,相邻两个探测单元相对位置关系已知,探测器参数Pd可以包括:多个探测单元中第1个探测单元在标定系统中的位置坐标,和多个探测单元的排列方向。For example, referring to Fig. 4A to Fig. 4D, the detector 30 may include a detector arm 320 and a plurality of detection units 310 mounted on the detector arm 320. The plurality of detection units 310 are arranged in a straight line on the detector arm 320. In this embodiment, the relative positional relationship between two adjacent detection units is known, and the detector parameter Pd may include: the position coordinates of the first detection unit among the plurality of detection units in the calibration system, and the arrangement direction of the plurality of detection units.

再例如,多个探测单元310在探测器臂上弧线排列,相邻两个探测单元相对位置关系已知,探测器参数Pd可以包括:多个探测单元中第1个探测单元在标定系统中的角度和半径。For another example, multiple detection units 310 are arranged in an arc on the detector arm, and the relative position relationship between two adjacent detection units is known. The detector parameter Pd may include: the angle and radius of the first detection unit among the multiple detection units in the calibration system.

在子步骤S730中,根据初始的射线源参数、初始的探测器参数以及几何标定模体50相对于射线源20和探测器30的位置关系,通过几何计算获得几何标定模体50在探测器30上的理论投影位置。In sub-step S730, according to the initial ray source parameters, the initial detector parameters and the positional relationship of the geometric calibration phantom 50 relative to the ray source 20 and the detector 30, the theoretical projection position of the geometric calibration phantom 50 on the detector 30 is obtained by geometric calculation.

例如,在子步骤S710中获取的探测器数据prji包括实际投影位置,即,从该探测器数据prji中,可以提取出几何标定模体50(例如金属丝)的实际投影位置,可以描述为pos(si,Pd)。可以理解,该实际投影位置为关于射线源参数和探测器参数的函数。For example, the detector data prj i obtained in sub-step S710 includes the actual projection position, that is, the actual projection position of the geometric calibration phantom 50 (such as a metal wire) can be extracted from the detector data prj i , which can be described as pos(s i , P d ). It can be understood that the actual projection position is a function of the ray source parameters and the detector parameters.

例如,在子步骤S730中,以旋转台420的旋转中心为坐标原点,根据旋转台420的转速以及几何标定模体50的位置,在已知初始的射线源参数si和探测器参数Pd的情况下,通过几何计算,可以获得与投影数据prji对应的几何标定模体50的理论投影位置,记为cpos(si,Pd)。可以理解,理论投影位置cpos(si,Pd)也是关于射线源参数和探测器参数的函数。For example, in sub-step S730, with the rotation center of the rotating stage 420 as the coordinate origin, according to the rotation speed of the rotating stage 420 and the position of the geometric calibration phantom 50, when the initial ray source parameter si and the detector parameter Pd are known, the theoretical projection position of the geometric calibration phantom 50 corresponding to the projection data prj i can be obtained through geometric calculation, which is recorded as cpos( si , Pd ). It can be understood that the theoretical projection position cpos( si , Pd ) is also a function of the ray source parameter and the detector parameter.

在子步骤S740中,根据实际投影位置和理论投影位置,对射线源参数和探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数。In sub-step S740, the ray source parameters and the detector parameters are calibrated according to the actual projection position and the theoretical projection position to obtain optimized ray source parameters and optimized detector parameters.

在子步骤S750中,将优化的射线源参数和优化的探测器参数确定为几何标定参数。In sub-step S750, the optimized ray source parameters and the optimized detector parameters are determined as geometric calibration parameters.

图8A是根据本公开的一些示例性实施例的标定方法中的几何标定步骤的获取优化的射线源参数和优化的探测器参数的示例性流程图。FIG8A is an exemplary flowchart of obtaining optimized ray source parameters and optimized detector parameters in a geometric calibration step in a calibration method according to some exemplary embodiments of the present disclosure.

参照图8A,在一些示例性的实施例中,子步骤S740可以包括子步骤S741~S742。8A , in some exemplary embodiments, sub-step S740 may include sub-steps S741 - S742 .

在子步骤S741中,构建实际投影位置和理论投影位置之间的偏差关于射线源参数和探测器参数的优化函数,在优化函数中,偏差为因变量,射线源参数和探测器参数为自变量。In sub-step S741, an optimization function of the deviation between the actual projection position and the theoretical projection position with respect to the ray source parameters and the detector parameters is constructed, in which the deviation is the dependent variable, and the ray source parameters and the detector parameters are the independent variables.

在子步骤S742中,根据优化函数,将偏差取值最小值时对应的射线源参数和探测器参数确定为优化的射线源参数和优化的探测器参数。In sub-step S742, according to the optimization function, the ray source parameters and detector parameters corresponding to when the deviation takes the minimum value are determined as optimized ray source parameters and optimized detector parameters.

例如,在该实施例中,可以通过求解如下的优化函数,来获得优化的射线源参数和优化的探测器参数:
For example, in this embodiment, the optimized ray source parameters and the optimized detector parameters can be obtained by solving the following optimization function:

其中,“argmin”是一个数学术语,用于表示一个函数在其定义域中取得最小值的参数值(自变量的值)。具体地,在该优化函数中,表示:当取得最小值时的射线源参数si和探测器参数Pd;si为射线源参数;Pd为探测器参数;Ns为分布式射线源中靶点的总数量;i表示的分布式射线源中某一个靶点的编号,1≤i≤Ns;pos(si,Pd)表示实际投影位置;cpos(si,Pd)表示理论投影位置。Among them, "argmin" is a mathematical term used to represent the parameter value (the value of the independent variable) of a function to achieve the minimum value in its domain. Specifically, in this optimization function, it means: The ray source parameter si and detector parameter Pd when the minimum value is obtained; si is the ray source parameter; Pd is the detector parameter; Ns is the total number of targets in the distributed ray source; i represents the number of a target in the distributed ray source, 1≤i≤Ns ; pos( si , Pd ) represents the actual projection position; cpos( si , Pd ) represents the theoretical projection position.

图8B是根据本公开的另一些示例性实施例的标定方法中的几何标定步骤的获取优化的射线源参数和优化的探测器参数的示例性流程图。FIG8B is an exemplary flowchart of obtaining optimized ray source parameters and optimized detector parameters in a geometric calibration step in a calibration method according to other exemplary embodiments of the present disclosure.

参照图8B,在一些示例性的实施例中,子步骤S740可以包括子步骤S743~S744。8B , in some exemplary embodiments, sub-step S740 may include sub-steps S743 - S744 .

在子步骤S743中,构建优化函数,优化函数包括投影位置约束项和靶点距离约束项,其中,投影位置约束项为实际投影位置和理论投影位置之间的偏差关于射线源参数和探测器参数的第一函数;靶点距离约束项为相邻的两个靶点之间的实际距离和理论距离之间的偏差关于射线源参数和探测器参数的第二函数。In sub-step S743, an optimization function is constructed, which includes a projection position constraint term and a target distance constraint term, wherein the projection position constraint term is a first function of the deviation between the actual projection position and the theoretical projection position with respect to the ray source parameters and the detector parameters; the target distance constraint term is a second function of the deviation between the actual distance and the theoretical distance between two adjacent target points with respect to the ray source parameters and the detector parameters.

例如,在优化函数中,投影位置约束项具有第一权重值,靶点距离约束项具有第二权重值。例如,第二权重值可以为0。For example, in the optimization function, the projection position constraint item has a first weight value, and the target distance constraint item has a second weight value. For example, the second weight value may be 0.

在子步骤S744中,根据优化函数,将实际投影位置和理论投影位置之间的偏差和相邻的两个靶点之间的实际距离和理论距离之间的偏差的加权求和取值最小值时对应的射线源参数和探测器参数确定为优化的射线源参数和优化的探测器参数。In sub-step S744, according to the optimization function, the corresponding ray source parameters and detector parameters when the weighted sum of the deviation between the actual projection position and the theoretical projection position and the deviation between the actual distance between two adjacent target points and the theoretical distance takes the minimum value are determined as the optimized ray source parameters and the optimized detector parameters.

在一些示例性的实施案例中,对优化的目标函数根据实际情况增加一些约束条件,使得优化问题的求解更稳定。例如,虽然靶点位置存在误差,但是靶点之间间隔偏差在一定范围内,则可以在优化函数中新增如下的靶点距离约束项,其中dis(si,si+1)表示靶点i和i+1之间的距离,ds表示两个靶点的理论间距,λ1和λ2表示两种约束的权重。In some exemplary implementation cases, some constraints are added to the optimization objective function according to the actual situation to make the solution of the optimization problem more stable. For example, although there is an error in the position of the target point, the deviation between the target points is within a certain range, and the following target point distance constraint term can be added to the optimization function, where dis(s i , s i+1 ) represents the distance between target points i and i+1, d s represents the theoretical distance between the two target points, and λ 1 and λ 2 represent the weights of the two constraints.

例如,在该实施例中,可以通过求解如下的优化函数,来获得优化的射线源参数和优化的探测器参数:
For example, in this embodiment, the optimized ray source parameters and the optimized detector parameters can be obtained by solving the following optimization function:

其中,“argmin”是一个数学术语,用于表示一个函数在其定义域中取得最小值的参数值(自变量的值)。具体地,在该优化函数中,表示:当 取得最小值时的射线源参数si和探测器参数Pd;si为射线源参数;Pd为探测器参数;Ns为分布式射线源中靶点的总数量;i表示的分布式射线源中某一个靶点的编号;pos(si,Pd)表示实际投影位置;cpos(si,Pd)表示理论投影位置;dis(si,si+1)表示靶点i和i+1之间的距离;ds表示两个靶点的理论间距;λ1和λ2表示两种约束的权重值。Among them, "argmin" is a mathematical term used to represent the parameter value (the value of the independent variable) of a function to achieve the minimum value in its domain. Specifically, in this optimization function, it means: The ray source parameter si and detector parameter Pd when the minimum value is obtained; si is the ray source parameter; Pd is the detector parameter; Ns is the total number of targets in the distributed ray source; i represents the number of a target in the distributed ray source; pos( si , Pd ) represents the actual projection position; cpos( si , Pd ) represents the theoretical projection position; dis( si , si +1 ) represents the distance between targets i and i+1; ds represents the theoretical spacing between two targets; λ1 and λ2 represent the weight values of the two constraints.

具体地,在上述优化函数中,为投影位置约束项,为靶点距离约束项。投影位置约束项的权重值为λ1,靶点距离约束项的权重值为λ2。例如,在一些示例性的实施例中,投影位置约束项的权重值λ1大于靶点距离约束项的权重值λ2,这样,在进行标定时,更多地考虑投影位置约束的影响因素。Specifically, in the above optimization function, is the projection position constraint, is the target distance constraint item. The weight value of the projection position constraint item is λ 1 , and the weight value of the target distance constraint item is λ 2 . For example, in some exemplary embodiments, the weight value λ 1 of the projection position constraint item is greater than the weight value λ 2 of the target distance constraint item, so that when performing calibration, the influencing factors of the projection position constraint are more considered.

下面,结合附图,描述执行能谱标定的步骤的详细实施方式。The following describes the detailed implementation of the steps of performing energy spectrum calibration in conjunction with the accompanying drawings.

结合参照图4A至图4B,在进行标定时,标定系统40放置在扫描成像设备的传送装置(例如图2所示的传送机构110)上,控制传送装置将标定系统40的能谱标定模体60输送到X射线的扫描平面,使得能谱标定模体60处于射线源20和探测器30组成的扫描平面内。例如,在进行能谱标定时,仅能谱标定模体60位于扫描平面内;或者,仅几何标定模体50和能谱标定模体60位于扫描平面内,标定系统40的其他部分始终处于扫描平面以外。这样,可以避免标定系统40的其他部分对标定数据造成干扰。With reference to FIGS. 4A to 4B , during calibration, the calibration system 40 is placed on a conveying device (e.g., the conveying mechanism 110 shown in FIG. 2 ) of the scanning imaging device, and the conveying device is controlled to transport the energy spectrum calibration phantom 60 of the calibration system 40 to the scanning plane of the X-ray, so that the energy spectrum calibration phantom 60 is in the scanning plane formed by the ray source 20 and the detector 30. For example, during energy spectrum calibration, only the energy spectrum calibration phantom 60 is in the scanning plane; or, only the geometric calibration phantom 50 and the energy spectrum calibration phantom 60 are in the scanning plane, and the other parts of the calibration system 40 are always outside the scanning plane. In this way, it is possible to avoid interference of other parts of the calibration system 40 with the calibration data.

图9是根据本公开的一些示例性实施例的标定方法中能谱标定步骤的流程图。结合参照图1至图9,所述标定方法可以用于对扫描成像设备进行能谱标定,例如,该标定方法可以对静态CT设备进行能谱标定。在该静态CT设备中,射线源20可以为分布式射线源,其包括Ns个靶点210,Ns个靶点沿第一方向间隔分布,其中,Ns为大于等于2的正整数。所述第一方向可以对应图3A所示的直线排列方向或图3B所示的弧线排列方法。需要说明的是,本公开的实施例中,不对分布式射线源的多个靶点的排列方向和形式做特别的限制。FIG9 is a flow chart of the energy spectrum calibration step in the calibration method according to some exemplary embodiments of the present disclosure. With reference to FIGS. 1 to 9, the calibration method can be used to perform energy spectrum calibration on a scanning imaging device. For example, the calibration method can perform energy spectrum calibration on a static CT device. In the static CT device, the ray source 20 can be a distributed ray source, which includes N s target points 210, and the N s target points are spaced and distributed along a first direction, wherein N s is a positive integer greater than or equal to 2. The first direction can correspond to the straight line arrangement direction shown in FIG3A or the arc arrangement method shown in FIG3B. It should be noted that in the embodiments of the present disclosure, no special restrictions are imposed on the arrangement direction and form of the multiple target points of the distributed ray source.

在本公开的一些实施例中,所述标定方法中的能谱标定步骤可以包括子步骤S910~S960。In some embodiments of the present disclosure, the energy spectrum calibration step in the calibration method may include sub-steps S910 to S960.

在子步骤S910中,在能谱标定模体位于所述射线形成的扫描区域中的情况下,根据所述射线源、所述能谱标定模体和所述探测器之间的相对位置,获取所述射线源、所述能谱标定模体和所述探测器之间的几何关系。In sub-step S910, when the energy spectrum calibration phantom is located in the scanning area formed by the rays, the geometric relationship between the ray source, the energy spectrum calibration phantom and the detector is acquired according to the relative positions between the ray source, the energy spectrum calibration phantom and the detector.

在子步骤S920中,通过所述探测器采集经过所述扫描区域的射线,以获取实际投影数据。In sub-step S920, the detector collects rays passing through the scanning area to obtain actual projection data.

在子步骤S930中,获取所述能谱标定模体的物理属性,其中,所述物理属性是根据所述能谱标定模体的组成材料预先确定的。In sub-step S930, the physical properties of the energy spectrum calibration phantom are obtained, wherein the physical properties are predetermined according to the constituent materials of the energy spectrum calibration phantom.

在子步骤S940中,基于所述能谱标定模体的物理属性和所述几何关系,使用预定的多个基础能谱计算理论投影数据。In sub-step S940, based on the physical properties of the energy spectrum calibration phantom and the geometric relationship, theoretical projection data are calculated using a predetermined plurality of basic energy spectra.

在子步骤S950中,根据所述理论投影数据和所述实际投影数据,对能谱参数进行标定,以获取优化的能谱参数。In sub-step S950, the energy spectrum parameters are calibrated according to the theoretical projection data and the actual projection data to obtain optimized energy spectrum parameters.

在子步骤S960中,将所述优化的能谱参数确定为能谱标定参数。In sub-step S960, the optimized energy spectrum parameters are determined as energy spectrum calibration parameters.

在该实施例中,能谱标定模体60可以为具有足够衰减能力的已知材料组成的具有一定形状的物体。例如,能谱标定模体60的材料可以选择石墨、有机玻璃、聚乙烯、聚甲醛、铝(合金)、镁(合金)、二氧化硅、聚氯乙烯、钛(合金)、铁、铜等。这些材料的化学成分和物理密度等属性为已知信息。In this embodiment, the energy spectrum calibration model 60 can be an object with a certain shape and composed of a known material with sufficient attenuation capability. For example, the material of the energy spectrum calibration model 60 can be selected from graphite, organic glass, polyethylene, polyoxymethylene, aluminum (alloy), magnesium (alloy), silicon dioxide, polyvinyl chloride, titanium (alloy), iron, copper, etc. The chemical composition and physical density of these materials are known information.

在该实施例中,由于能谱标定模体60的物理属性是可以预先确定的,所以,在子步骤S930中,获取的能谱标定模体60的物理属性是准确的。相应地,在子步骤S940中,基于能谱标定模体60的准确的物理属性和几何关系,可以计算出准确的理论投影数据。在子步骤S950中获取的优化能谱参数可以作为最终的能谱标定参数,无需进行迭代。In this embodiment, since the physical properties of the energy spectrum calibration phantom 60 can be predetermined, the physical properties of the energy spectrum calibration phantom 60 obtained in sub-step S930 are accurate. Accordingly, in sub-step S940, accurate theoretical projection data can be calculated based on the accurate physical properties and geometric relationship of the energy spectrum calibration phantom 60. The optimized energy spectrum parameters obtained in sub-step S950 can be used as the final energy spectrum calibration parameters without iteration.

图10是根据本公开的另一些示例性实施例的标定方法中能谱标定步骤的流程图。在本公开的另一些实施例中,所述标定方法中的能谱标定步骤可以包括子步骤S1010~S1060。Fig. 10 is a flow chart of an energy spectrum calibration step in a calibration method according to some other exemplary embodiments of the present disclosure. In some other embodiments of the present disclosure, the energy spectrum calibration step in the calibration method may include sub-steps S1010 to S1060.

在子步骤S1010中,在能谱标定模体位于所述射线形成的扫描区域中的情况下,根据所述射线源、所述能谱标定模体和所述探测器之间的相对位置,获取所述射线源、所述能谱标定模体和所述探测器之间的几何关系。In sub-step S1010, when the energy spectrum calibration phantom is located in the scanning area formed by the rays, the geometric relationship between the ray source, the energy spectrum calibration phantom and the detector is acquired according to the relative positions between the ray source, the energy spectrum calibration phantom and the detector.

在子步骤S1020中,通过所述探测器采集经过所述扫描区域的射线,以获取实际投影数据。In sub-step S1020, the detector collects rays passing through the scanning area to obtain actual projection data.

在子步骤S1030中,执行循环过程直至满足预设条件,所述第一循环过程包括子步骤S1031~子步骤S1034。In sub-step S1030, a loop process is executed until a preset condition is met, and the first loop process includes sub-steps S1031 to S1034.

在子步骤S1031中,根据能谱信息,对所述能谱标定模体进行图像重建,根据所述图像重建的结果获取所述能谱标定模体的物理属性。In sub-step S1031, image reconstruction is performed on the energy spectrum calibration phantom according to the energy spectrum information, and physical properties of the energy spectrum calibration phantom are obtained according to the result of the image reconstruction.

在子步骤S1032中,基于所述能谱标定模体的物理属性和所述几何关系,使用预定的多个基础能谱计算理论投影数据。In sub-step S1032, based on the physical properties of the energy spectrum calibration phantom and the geometric relationship, theoretical projection data are calculated using a predetermined plurality of basic energy spectra.

在子步骤S1033中,根据所述理论投影数据和所述实际投影数据,对能谱参数进行标定,以获取优化的能谱参数。In sub-step S1033, the energy spectrum parameters are calibrated according to the theoretical projection data and the actual projection data to obtain optimized energy spectrum parameters.

在子步骤S1034中,基于所述优化的能谱参数,获取能谱信息。In sub-step S1034, energy spectrum information is acquired based on the optimized energy spectrum parameters.

在子步骤S1040中,将所述第一循环过程中最后一次获得的优化的能谱参数,确定为能谱标定参数。In sub-step S1040, the optimized energy spectrum parameters obtained last time during the first cycle are determined as energy spectrum calibration parameters.

在该实施例中,能谱标定模体60可以为具有足够衰减能力的未知材料组成的具有一定形状的物体。例如,能谱标定模体60的材料可以选择一些物理化学性质稳定的材料,但材料的成分比例信息无法准确获得的材料。也就是说,能谱标定模体60的物理属性是无法预先确定的。In this embodiment, the energy spectrum calibration phantom 60 can be an object with a certain shape composed of unknown materials with sufficient attenuation ability. For example, the material of the energy spectrum calibration phantom 60 can be selected from some materials with stable physical and chemical properties, but the composition ratio information of the material cannot be accurately obtained. In other words, the physical properties of the energy spectrum calibration phantom 60 cannot be predetermined.

在该实施例中,可以通过图像重建的方法,来确定能谱标定模体60的物理属性。返回参照图1,在反向投影(也称为后向投影)中,已知探测器D上的图像点的投影值,求取被扫描对象OB上的空间点的像素值。在该实施例中,在子步骤S1020中,获取了实际投影数据,即探测器上的投影值,通过反向投影算法或图像重建算法,可以计算出被扫描对象(即能谱标定模体)的图像,该重建的图像对应能谱标定模体60的物理属性。In this embodiment, the physical properties of the energy spectrum calibration phantom 60 can be determined by an image reconstruction method. Referring back to FIG. 1 , in reverse projection (also called back projection), the projection value of the image point on the detector D is known, and the pixel value of the spatial point on the scanned object OB is obtained. In this embodiment, in sub-step S1020, the actual projection data, i.e., the projection value on the detector, is obtained, and the image of the scanned object (i.e., the energy spectrum calibration phantom) can be calculated by a reverse projection algorithm or an image reconstruction algorithm, and the reconstructed image corresponds to the physical properties of the energy spectrum calibration phantom 60.

在图4A、图4B和图6对应的实施例中,在几何标定模体和能谱标定模体两者均位于所述射线形成的扫描区域中的情况下,执行几何标定步骤和能谱标定步骤。具体地,在步骤S610中,通过所述探测器30采集经过所述扫描区域的射线,获取与所述几何标定模体和所述能谱标定模体均相关的探测器数据。也就是说,该探测器数据包括几何标定模体50和能谱标定模体60两者的信息。在该情况下,在进行能谱标定模体的图像重建时,需要对图像进行分割处理,分割出几何标定模体50和能谱标定模体60。In the embodiments corresponding to FIG. 4A , FIG. 4B and FIG. 6 , when both the geometric calibration phantom and the energy spectrum calibration phantom are located in the scanning area formed by the rays, the geometric calibration step and the energy spectrum calibration step are performed. Specifically, in step S610, the rays passing through the scanning area are collected by the detector 30 to obtain detector data related to both the geometric calibration phantom and the energy spectrum calibration phantom. In other words, the detector data includes information of both the geometric calibration phantom 50 and the energy spectrum calibration phantom 60. In this case, when reconstructing the image of the energy spectrum calibration phantom, it is necessary to segment the image to segment the geometric calibration phantom 50 and the energy spectrum calibration phantom 60.

例如,在子步骤S1031中,根据能谱信息,对所述几何标定模体50和所述能谱标定模体60进行图像重建,以获取第一重建图像;对所述第一重建图像进行分割处理,分割出所述几何标定模体50和所述能谱标定模体60,以获取第二重建图像;和根据所述第二重建图像获取所述能谱标定模体60的物理属性。For example, in sub-step S1031, the geometric calibration phantom 50 and the energy spectrum calibration phantom 60 are reconstructed according to the energy spectrum information to obtain a first reconstructed image; the first reconstructed image is segmented to segment the geometric calibration phantom 50 and the energy spectrum calibration phantom 60 to obtain a second reconstructed image; and the physical properties of the energy spectrum calibration phantom 60 are obtained according to the second reconstructed image.

需要说明的是,在图5对应的实施例中,由于能谱标定是单独执行的,所以,在能谱标定过程中进行图像重建时,不需要执行图像分割处理。It should be noted that, in the embodiment corresponding to FIG. 5 , since the energy spectrum calibration is performed separately, it is not necessary to perform image segmentation processing when image reconstruction is performed during the energy spectrum calibration process.

还需要说明的是,在该实施例中,可以使用本领域中各种已知的反向投影算法或图像重建算法进行图像重建,本公开的实施例不对此做特别的限制。It should also be noted that, in this embodiment, various back-projection algorithms or image reconstruction algorithms known in the art may be used to perform image reconstruction, and the embodiments of the present disclosure do not impose any particular limitation on this.

应该理解,根据实际投影数据通过图像重建算法确定出的能谱标定模体的物理属性可能是不准确的,所以,在该实施例中,需要执行第一循环过程,通过该循环过程,使得获取的能谱标定模体的物理属性可以无限逼近能谱标定模体的准确的物理属性,这样,可以提高能谱标定的准确度。It should be understood that the physical properties of the energy spectrum calibration phantom determined by the image reconstruction algorithm based on the actual projection data may be inaccurate. Therefore, in this embodiment, it is necessary to execute a first loop process. Through this loop process, the physical properties of the acquired energy spectrum calibration phantom can be infinitely close to the accurate physical properties of the energy spectrum calibration phantom. In this way, the accuracy of the energy spectrum calibration can be improved.

需要说明的是,除非另有特别说明或在有冲突的情况下,在下文中描述的步骤或方法可以适用于上文描述的各个实施例中。具体地,在没有特别说明的情况下,下面描述的各个步骤可以适用于上文中针对图9和图10描述的标定方法两者中。It should be noted that, unless otherwise specified or in case of conflict, the steps or methods described below can be applied to the various embodiments described above. Specifically, unless otherwise specified, the various steps described below can be applied to both the calibration methods described above for Figures 9 and 10.

在子步骤S910或子步骤S1010中,可以采用上述各个实施例中描述的几何标定步骤来获取射线源参数si和探测器参数PdIn sub-step S910 or sub-step S1010, the geometric calibration steps described in the above embodiments may be used to obtain the ray source parameters si and the detector parameters P d .

能谱标定模体60设置于旋转台420上,其在标定系统40中的位置也是预先确定的,或者说,其在标定系统40中的位置是根据旋转台420在标定系统40中的位置以及能谱标定模体60在旋转台420上的位置确定的。通过这样的方式,在能谱标定模体60位于所述射线形成的扫描区域中的情况下,可以根据所述射线源20、所述能谱标定模体60和所述探测器30之间的相对位置,获取所述射线源20、所述能谱标定模体60和所述探测器30之间的几何关系。The energy spectrum calibration phantom 60 is arranged on the rotating table 420, and its position in the calibration system 40 is also predetermined, or in other words, its position in the calibration system 40 is determined according to the position of the rotating table 420 in the calibration system 40 and the position of the energy spectrum calibration phantom 60 on the rotating table 420. In this way, when the energy spectrum calibration phantom 60 is located in the scanning area formed by the ray, the geometric relationship between the ray source 20, the energy spectrum calibration phantom 60 and the detector 30 can be obtained according to the relative positions among the ray source 20, the energy spectrum calibration phantom 60 and the detector 30.

返回参照图5,在步骤S510中,将几何标定模体50置于旋转台420上,然后使几何标定模体50运动至扫描区域中。在几何标定完成之后,在步骤S520中,将能谱标定模体60置于旋转台420上,然后使能谱标定模体60运动至扫描区域中。在该情况下,在进行能谱标定时,需要对旋转台420相对于射线源20和探测器30的相对位置进行再次标定。Referring back to FIG. 5 , in step S510, the geometric calibration phantom 50 is placed on the rotating stage 420, and then the geometric calibration phantom 50 is moved into the scanning area. After the geometric calibration is completed, in step S520, the energy spectrum calibration phantom 60 is placed on the rotating stage 420, and then the energy spectrum calibration phantom 60 is moved into the scanning area. In this case, when performing the energy spectrum calibration, the relative position of the rotating stage 420 relative to the radiation source 20 and the detector 30 needs to be calibrated again.

在一些示例性的实施例中,在确定所述射线源、所述能谱标定模体和所述探测器之间的相对位置之前,所述方法还包括:标定承载所述能谱标定模体的标定装置主体(例如旋转台420)相对于所述射线源20和所述探测器30的相对位置。In some exemplary embodiments, before determining the relative positions between the radiation source, the energy spectrum calibration phantom and the detector, the method further includes: calibrating the relative position of a calibration device body (e.g., a rotating table 420) carrying the energy spectrum calibration phantom relative to the radiation source 20 and the detector 30.

在一些实施例中,可以通过标定标定装置主体(例如旋转台420)的中心坐标来标定标定装置主体(例如旋转台420)相对于所述射线源20和所述探测器30的相对位置。In some embodiments, the relative position of the calibration device body (eg, the rotating stage 420 ) with respect to the radiation source 20 and the detector 30 may be calibrated by calibrating the center coordinates of the calibration device body (eg, the rotating stage 420 ).

例如,在该实施例中,可以通过求解如下的优化函数,来获得进行旋转台420的优化的中心坐标(例如旋转中心的坐标):
For example, in this embodiment, the center coordinates (eg, coordinates of the rotation center) for optimizing the rotating stage 420 may be obtained by solving the following optimization function:

其中,“argmin”是一个数学术语,用于表示一个函数在其定义域中取得最小值的参数值(自变量的值)。具体地,在该优化函数中,表示:当取得最小值时的旋转台420的旋转中心的坐标x0;Ns为分布式射线源中靶点的总数量;i表示的分布式射线源中某一个靶点的编号,1≤i≤Ns;pos(si,Pd)表示实际投影位置;cpos(si,Pd)表示理论投影位置。Among them, "argmin" is a mathematical term used to represent the parameter value (the value of the independent variable) of a function to achieve the minimum value in its domain. Specifically, in this optimization function, it means: The coordinate x 0 of the rotation center of the rotating stage 420 when the minimum value is obtained; N s is the total number of targets in the distributed ray source; i represents the number of a target in the distributed ray source, 1≤i≤N s ; pos(s i ,P d ) represents the actual projection position; cpos(s i ,P d ) represents the theoretical projection position.

返回参照图4A、图4B和图6,所在几何标定模体50和能谱标定模体60两者均位于所述射线形成的扫描区域中的情况下,执行几何标定步骤和能谱标定步骤。也就是说,几何标定和能谱标定是基于相同的探测器数据执行的。在该情况下,在进行能谱标定时,标定装置主体(例如旋转台420)的中心即为几何标定步骤中定义的坐标原点,不需要重新标定标定装置主体(例如旋转台420)相对于所述射线源20和所述探测器30的相对位置。Referring back to FIG. 4A , FIG. 4B and FIG. 6 , when both the geometric calibration phantom 50 and the energy spectrum calibration phantom 60 are located in the scanning area formed by the ray, the geometric calibration step and the energy spectrum calibration step are performed. That is, the geometric calibration and the energy spectrum calibration are performed based on the same detector data. In this case, when performing the energy spectrum calibration, the center of the calibration device body (e.g., the rotating table 420) is the coordinate origin defined in the geometric calibration step, and there is no need to recalibrate the relative position of the calibration device body (e.g., the rotating table 420) relative to the ray source 20 and the detector 30.

在一些示例性的实施例中,所述标定方法可以包括:在将能谱标定模体60置于射线形成的扫描区域或扫描平面之前,通过探测器30采集空气投影数据pairIn some exemplary embodiments, the calibration method may include: before placing the energy spectrum calibration phantom 60 in a scanning area or a scanning plane formed by rays, collecting air projection data p air by the detector 30 .

在子步骤S920或S1020中,所述获得探测器数据包括:通过探测器30采集经过扫描区域(能谱标定模体60位于该扫描区域中)的射线,获得初始探测器数据pi;以及,利用空气投影数据pair,采用第一校正方法对对初始探测器数据pi进行校正,以获得第一校正投影数据prjiIn sub-step S920 or S1020, obtaining the detector data includes: collecting rays passing through a scanning area (where the energy spectrum calibration phantom 60 is located) through the detector 30 to obtain initial detector data p i ; and correcting the initial detector data p i using a first correction method using the air projection data p air to obtain first corrected projection data prj i .

需要说明的是,在本文中,1≤i≤Ns,即,i表示的分布式射线源中某一个靶点210的编号。It should be noted that, in this article, 1≤i≤N s , that is, i represents the number of a target point 210 in the distributed ray source.

例如,可以利用以下的公式来进行第一校正,以获得第一校正投影数据prji:prji=pi/pairFor example, the first correction may be performed using the following formula to obtain the first corrected projection data prj i : prj i = p i / p air .

可替换地或附加地,在子步骤S1020中,所述获得探测器数据包括:通过探测器30采集经过扫描区域(能谱标定模体60位于该扫描区域中)的射线,获得初始探测器数据pi;利用空气投影数据pair,采用第一校正方法对对初始探测器数据pi进行校正,以获得第一校正投影数据prji;和/或,利用所述空气数据,采用第二校正方法对所述初始投影数据pi进行校正,以获取第二校正投影数据pprjiAlternatively or additionally, in sub-step S1020, obtaining the detector data includes: acquiring, by the detector 30, rays passing through a scanning area (where the energy spectrum calibration phantom 60 is located), to obtain initial detector data p i ; using the air projection data p air , correcting the initial detector data p i using a first correction method to obtain first corrected projection data prj i ; and/or, using the air data, correcting the initial projection data p i using a second correction method to obtain second corrected projection data pprj i .

在一些示例性的实施例中,第一校正方法和第二校正方法不同。例如,可以利用以下的公式来进行第一校正,以获得第一校正投影数据prji:prji=pi/pair。例如,可以利用以下的公式来进行第二校正,以获得第二校正投影数据pprji:pprji=-log(pi/pair)。In some exemplary embodiments, the first correction method and the second correction method are different. For example, the first correction can be performed using the following formula to obtain the first corrected projection data prj i : prj i = p i / p air . For example, the second correction can be performed using the following formula to obtain the second corrected projection data pprj i : pprj i = -log(p i / p air ).

需要说明的是,第一校正投影数据prji是在后面的步骤中作为正向投影数据使用,所以,其直接除以空气投影数据;第二校正投影数据pprji在后面的步骤中是用于图像重建的,所以,其需要取对数的负值。例如,此处的对数可以是以10为底的对数。It should be noted that the first corrected projection data prj i is used as forward projection data in the following steps, so it is directly divided by the air projection data; the second corrected projection data pprj i is used for image reconstruction in the following steps, so it needs to take the negative value of the logarithm. For example, the logarithm here can be a logarithm with base 10.

在本公开的一些示例性的实施例中,标定系统40包括旋转台420,能谱标定模体60位于旋转台420上。In some exemplary embodiments of the present disclosure, the calibration system 40 includes a rotating stage 420 , and the energy spectrum calibration phantom 60 is located on the rotating stage 420 .

在该实施例中,获得初始探测器数据pi可以包括:控制射线源20发出射线;控制旋转台420旋转,以带动能谱标定模体60旋转m圈,其中,m为大于等于1的正整数;以及,在能谱标定模体60旋转m圈的过程中,探测器30采集从射线源20发出且经过扫描区域的射线。In this embodiment, obtaining the initial detector data p i may include: controlling the ray source 20 to emit rays; controlling the rotating table 420 to rotate to drive the energy spectrum calibration model 60 to rotate m circles, where m is a positive integer greater than or equal to 1; and, during the process of the energy spectrum calibration model 60 rotating m circles, the detector 30 collects rays emitted from the ray source 20 and passing through the scanning area.

在本公开的一些示例性的实施例中,标定系统40包括升降台440,能谱标定模体60位于升降台440上。In some exemplary embodiments of the present disclosure, the calibration system 40 includes a lifting platform 440 , and the energy spectrum calibration phantom 60 is located on the lifting platform 440 .

在该实施例中,获得初始探测器数据pi可以包括:控制射线源20发出射线;控制升降台440升降,以带动能谱标定模体60升降。In this embodiment, obtaining the initial detector data p i may include: controlling the ray source 20 to emit rays; and controlling the lifting platform 440 to move up and down, so as to drive the energy spectrum calibration phantom 60 to move up and down.

例如,通过升降台440的升降运动,可以带动能谱标定模体60上升至扫描位置。在升降过程中,探测器可以不采集数据。For example, the energy spectrum calibration phantom 60 may be driven to rise to the scanning position by the lifting and lowering movement of the lifting platform 440. During the lifting and lowering process, the detector may not collect data.

再例如,在能谱标定模体60升降过程中,探测器30可以采集从射线源20发出且经过扫描区域的射线。在一些可选的实施例中,在升降过程中采集的数据可以不用于后续的处理。For another example, during the lifting process of the energy spectrum calibration phantom 60, the detector 30 may collect radiation emitted from the radiation source 20 and passing through the scanning area. In some optional embodiments, the data collected during the lifting process may not be used for subsequent processing.

在本公开的一些示例性的实施例中,射线源20包括Ns个靶点210,Ns个靶点210沿第一方向间隔分布,其中,Ns为大于等于2的正整数。In some exemplary embodiments of the present disclosure, the ray source 20 includes N s target points 210 , and the N s target points 210 are spaced apart along the first direction, where N s is a positive integer greater than or equal to 2.

在该实施例中,获得初始探测器数据pi可以包括:控制Ns个靶点210按照设定顺序发出射线;以及在Ns个靶点210按照设定顺序发出射线的过程中,探测器30采集从射线源20发出且经过扫描区域的射线。In this embodiment, obtaining the initial detector data pi may include: controlling the Ns target points 210 to emit radiation in a set order; and in the process of the Ns target points 210 emitting radiation in the set order, the detector 30 collects radiation emitted from the radiation source 20 and passing through the scanning area.

在本公开的一些示例性的实施例中,标定系统40包括旋转台420,能谱标定模体60位于旋转台420上。射线源20包括Ns个靶点210,Ns个靶点210沿第一方向间隔分布,其中,Ns为大于等于2的正整数。In some exemplary embodiments of the present disclosure, the calibration system 40 includes a rotating table 420, and the energy spectrum calibration phantom 60 is located on the rotating table 420. The ray source 20 includes Ns target points 210, which are spaced apart along the first direction, wherein Ns is a positive integer greater than or equal to 2.

在该实施例中,获得初始探测器数据pi可以包括:控制Ns个靶点210按照设定顺序发出射线;控制旋转台420旋转,以带动能谱标定模体60旋转m圈,其中,m为大于等于1的正整数;以及在Ns个靶点210按照设定顺序发出射线和能谱标定模体60旋转m圈的过程中,探测器30采集从射线源发出且经过扫描区域的射线。In this embodiment, obtaining the initial detector data p i may include: controlling the N s target points 210 to emit rays in a set order; controlling the rotating table 420 to rotate to drive the energy spectrum calibration phantom 60 to rotate m circles, where m is a positive integer greater than or equal to 1; and in the process of the N s target points 210 emitting rays in a set order and the energy spectrum calibration phantom 60 rotating m circles, the detector 30 collects rays emitted from the ray source and passing through the scanning area.

需要说明的是,在本公开的实施例中,对能谱标定模体的运动形式、设置数量和射线源的靶点数量不做特别的限制,在不冲突的情况下,各种情况可以相互组合和结合。例如,在一些实施例中,能谱标定模体60可以设置在旋转台上,旋转台设置在升降台上,射线源20可以为包括多个靶点的分布式射线源,这样,获得探测器数据prji的步骤可以根据该设置方式进行相应调整,在此不再赘述。It should be noted that in the embodiments of the present disclosure, there is no particular restriction on the movement form, setting number and target number of the energy spectrum calibration phantom, and various situations can be combined and combined with each other without conflict. For example, in some embodiments, the energy spectrum calibration phantom 60 can be set on a rotating table, the rotating table is set on a lifting table, and the ray source 20 can be a distributed ray source including multiple target points. In this way, the step of obtaining the detector data prj i can be adjusted accordingly according to the setting mode, which will not be repeated here.

还需要说明的是,在本公开的实施例中,能谱标定模体60的运动和射线源的出束的顺序可以不做特别限制。例如,能谱标定模体60固定于一个位置,控制所有靶点按照设定顺序出一次束,然后旋转台旋转至下一个位置,控制所有靶点再次出束,直至旋转台旋转一周后结束。It should also be noted that in the embodiments of the present disclosure, the movement of the energy spectrum calibration phantom 60 and the order of the beam emission of the radiation source may not be particularly limited. For example, the energy spectrum calibration phantom 60 is fixed at one position, and all the targets are controlled to emit beams once in a set order, and then the rotating stage rotates to the next position, and all the targets are controlled to emit beams again, until the rotating stage rotates one circle and ends.

如上所述,发明人经研究发现,在静态CT设备中,由于单个晶体需要接收不同靶点发出的射线,因此不同靶点射线的入射角度不同,穿过的晶体厚度不同,从而导致吸收能谱不同。所以,在本公开的一些示例性实施例中,可以先对获取的第一校正投影数据prji进行归类,然后,针对归类后的每一类投影数据,分别进行能谱标定。As described above, the inventors have found through research that in a static CT device, since a single crystal needs to receive rays emitted by different targets, the rays from different targets have different incident angles and pass through different crystal thicknesses, resulting in different absorption energy spectra. Therefore, in some exemplary embodiments of the present disclosure, the acquired first corrected projection data prj i may be classified first, and then, for each type of classified projection data, energy spectrum calibration may be performed respectively.

具体地,在子步骤S920或子步骤S1020中,所述通过所述探测器采集经过所述扫描区域的射线,以获取实际投影数据,还可以包括:根据预定的归类标准,将所述第一校正投影数据prji进行归类,以获取Nc个类别的投影数据,将第j个类别的投影数据作为实际投影数据,其中,第j个类别的投影数据为所述Nc个类别中的一类投影数据,Nc为大于等于1的正整数,1≤j≤Nc;所述预定的归类标准是基于影响探测器的吸收能谱的因素而确定的。Specifically, in sub-step S920 or sub-step S1020, collecting the rays passing through the scanning area through the detector to obtain actual projection data may also include: classifying the first corrected projection data prj i according to a predetermined classification standard to obtain projection data of N c categories, and taking the projection data of the jth category as actual projection data, wherein the projection data of the jth category is a category of projection data in the N c categories, N c is a positive integer greater than or equal to 1, 1≤j≤N c ; and the predetermined classification standard is determined based on factors that affect the absorption energy spectrum of the detector.

在一些示例性的实施例中,所述基于影响探测器的吸收能谱的因素包括以下因素中的至少一个:射线的出射角度;射线入射到探测器上的入射角度;射线源的靶点的能谱分布;和射线从射线源至探测器的路径中的遮挡情况。在该实施例中,将射线的出射角度、射线入射到探测器上的入射角度和射线传播路径中的遮挡情况相同或相似的能谱归为同一类,针对该同一类的能谱进行标定,有利于提高能谱标定的准确度。In some exemplary embodiments, the factors affecting the absorption energy spectrum of the detector include at least one of the following factors: the emission angle of the ray; the incident angle of the ray incident on the detector; the energy spectrum distribution of the target point of the ray source; and the shielding of the ray in the path from the ray source to the detector. In this embodiment, energy spectra with the same or similar emission angle of the ray, the incident angle of the ray incident on the detector, and the shielding in the ray propagation path are classified into the same category, and the energy spectra of the same category are calibrated, which is conducive to improving the accuracy of energy spectrum calibration.

在子步骤S940或子步骤S1032中,基于所述能谱标定模体60的物理属性和所述几何关系,使用预定的多个基础能谱计算理论投影数据。需要说明的是,在子步骤S940中,所述能谱标定模体60的物理属性是根据能谱标定模体60的材料和组成预先确定的;在子步骤S1032中,所述能谱标定模体60的物理属性是根据图像重建算法估计出的。In sub-step S940 or sub-step S1032, the theoretical projection data is calculated using a predetermined plurality of basic energy spectra based on the physical properties of the energy spectrum calibration phantom 60 and the geometric relationship. It should be noted that in sub-step S940, the physical properties of the energy spectrum calibration phantom 60 are predetermined based on the material and composition of the energy spectrum calibration phantom 60; and in sub-step S1032, the physical properties of the energy spectrum calibration phantom 60 are estimated based on an image reconstruction algorithm.

需要说明的是,在本文中,“多个基础能谱”可以选择实测的不同能量下的能谱,也可以选择使用蒙卡模拟获得,所述多个基础能谱是根据被扫描对象需要的感兴趣能谱而预先确定的。It should be noted that, in this article, the “multiple basic energy spectra” can be selected from actually measured energy spectra at different energies, or can be obtained using Monte Carlo simulation. The multiple basic energy spectra are predetermined based on the energy spectra of interest required by the scanned object.

在一些示例性的实施例中,在子步骤S940或子步骤S1032中,所述基于所述能谱标定模体的物理属性和所述几何关系,使用预定的多个基础能谱计算理论投影数据,具体包括:选择Ne个基础能谱{Sk(E)};以及依次针对Ne个基础能谱{Sk(E)},基于所述能谱标定模体60的物理属性和所述几何关系,计算Ne个理论投影数据。例如,Ne为大于等于2的正整数。In some exemplary embodiments, in sub-step S940 or sub-step S1032, the calculating theoretical projection data using a predetermined plurality of basic energy spectra based on the physical properties of the energy spectrum calibration phantom and the geometric relationship specifically includes: selecting Ne basic energy spectra {S k (E)}; and sequentially calculating Ne theoretical projection data for Ne basic energy spectra {S k (E)} based on the physical properties and the geometric relationship of the energy spectrum calibration phantom 60. For example, Ne is a positive integer greater than or equal to 2.

在已知Ne个基础能谱{Sk(E)}、能谱标定模体60的物理属性和所述几何关系的情况下,可以使用已知的各种正向投影算法,计算出理论投影数据。When Ne basic energy spectra {S k (E)}, the physical properties of the energy spectrum calibration phantom 60 and the geometric relationship are known, various known forward projection algorithms can be used to calculate theoretical projection data.

例如,可以使用下面的公式来计算第k个理论投影数据sprjk
For example, the k-th theoretical projection data sprj k may be calculated using the following formula:

在该公式中,sprjk为使用第k个基础能谱计算出的第k个理论投影数据,1≤k≤Ne,Sk(E)为第k个基础能谱,表示在位置或距离处的被扫描对象对能量E的射线的线性吸收系数,dl为沿射线路径积分,dE为关于能量积分。In this formula, sprj k is the kth theoretical projection data calculated using the kth basic energy spectrum, 1≤k≤N e , S k (E) is the kth basic energy spectrum, Indicates location or distance The linear absorption coefficient of the scanned object at dl for the ray of energy E, dl is the integral along the ray path, and dE is the integral about the energy.

再例如,如上所述,需要针对每一个类别的实际投影数据,分别计算理论投影数据,所以,上述公式可以变化如下,即,可以使用下面的公式来计算使用第k个基础能谱计算出的与第j个类别的投影数据对应的第k个理论投影数据sprjj,k
For another example, as described above, it is necessary to calculate theoretical projection data for each category of actual projection data, so the above formula can be changed as follows, that is, the following formula can be used to calculate the k-th theoretical projection data sprj j,k corresponding to the j-th category of projection data calculated using the k-th basic energy spectrum:

在该公式中,sprjj,k为使用第k个基础能谱计算出的与第j个类别的投影数据对应的第k个理论投影数据,1≤k≤Ne,Sk(E)为第k个基础能谱,表示在位置或距离处的被扫描对象对能量E的射线的线性吸收系数,dl为沿射线路径积分,dE为关于能量积分。In this formula, sprj j,k is the kth theoretical projection data corresponding to the jth category projection data calculated using the kth basic energy spectrum, 1≤k≤N e , S k (E) is the kth basic energy spectrum, Indicates location or distance The linear absorption coefficient of the scanned object at dl for the ray of energy E, dl is the integral along the ray path, and dE is the integral about the energy.

需要说明的是,上述公式仅为示例性的,本公开的实施例对于计算理论投影数据的具体公式不作特别的限制。It should be noted that the above formula is only exemplary, and the embodiments of the present disclosure do not impose any particular limitation on the specific formula for calculating the theoretical projection data.

也就是说,在本公开的一些示例性实施例中,所述基于所述能谱标定模体的物理属性和所述几何关系,使用预定的多个基础能谱计算理论投影数据,可以包括一个循环过程。例如,所述基于所述能谱标定模体的物理属性和所述几何关系,使用预定的多个基础能谱计算理论投影数据,可以包括:依次针对Nc个类别的投影数据,执行第二循环过程。所述第二循环过程包括:针对第j个类别的投影数据,选择Ne个基础能谱{Sk(E)};以及依次针对Ne个基础能谱{Sk(E)},基于所述能谱标定模体的物理属性和所述几何关系,计算与第j个类别的投影数据对应的Ne个理论投影数据。That is, in some exemplary embodiments of the present disclosure, the method of calculating theoretical projection data based on the physical properties of the energy spectrum calibration phantom and the geometric relationship using a predetermined plurality of basic energy spectra may include a loop process. For example, the method of calculating theoretical projection data based on the physical properties of the energy spectrum calibration phantom and the geometric relationship using a predetermined plurality of basic energy spectra may include: executing a second loop process for N c categories of projection data in sequence. The second loop process includes: selecting N e basic energy spectra {S k (E)} for the j-th category of projection data; and calculating N e theoretical projection data corresponding to the j-th category of projection data based on the physical properties of the energy spectrum calibration phantom and the geometric relationship in sequence for the N e basic energy spectra {S k (E)}.

在一些示例性的实施例中,在子步骤S1031中,可以根据能谱信息,基于所述第二校正投影数据pprji,对所述能谱标定模体60进行图像重建。In some exemplary embodiments, in sub-step S1031, the image of the energy spectrum calibration phantom 60 may be reconstructed according to the energy spectrum information and based on the second corrected projection data pprj i .

由于能谱标定模体60位于扫描平面内,X射线覆盖整个能谱标定模体60,旋转台420带动能谱标定模体60旋转一周,上述步骤中获取的第二校正投影数据pprji对于CT重建是完备的,结合射线源、探测器的坐标或相对位置,探测器的积分时间,旋转台420的位置,旋转台420的旋转速度,以及能谱信息,可以对能谱标定模体60进行CT重建,以获取重建图像。可以理解,所述重建图像可以包括能谱标定模体60的图像,其反映了能谱标定模体60的物理属性。Since the energy spectrum calibration phantom 60 is located in the scanning plane, the X-ray covers the entire energy spectrum calibration phantom 60, and the rotating table 420 drives the energy spectrum calibration phantom 60 to rotate one circle. The second correction projection data pprj i obtained in the above steps is complete for CT reconstruction. Combined with the coordinates or relative positions of the ray source and the detector, the integration time of the detector, the position of the rotating table 420, the rotation speed of the rotating table 420, and the energy spectrum information, the energy spectrum calibration phantom 60 can be CT reconstructed to obtain a reconstructed image. It can be understood that the reconstructed image may include an image of the energy spectrum calibration phantom 60, which reflects the physical properties of the energy spectrum calibration phantom 60.

图11是根据本公开的一些示例性实施例的标定方法中的获取优化的能谱参数的示例性流程图。FIG. 11 is an exemplary flowchart of obtaining optimized energy spectrum parameters in a calibration method according to some exemplary embodiments of the present disclosure.

参照图11,在一些示例性的实施例中,子步骤S950或子步骤S1033可以包括子步骤S1110~S1120。11 , in some exemplary embodiments, sub-step S950 or sub-step S1033 may include sub-steps S1110 - S1120 .

在子步骤S1110中,构建所述理论投影数据和所述实际投影数据之间的偏差关于能谱参数的优化函数。In sub-step S1110, an optimization function of the deviation between the theoretical projection data and the actual projection data with respect to energy spectrum parameters is constructed.

例如,在该优化函数中,偏差为因变量,能谱参数为自变量。For example, in the optimization function, the deviation is the dependent variable and the energy spectrum parameter is the independent variable.

在子步骤S1120中,根据所述优化函数,对能谱参数进行标定,以获取优化的能谱参数。In sub-step S1120, the energy spectrum parameters are calibrated according to the optimization function to obtain optimized energy spectrum parameters.

例如,在一些示例性的实施例中,可以通过求解如下的优化函数,来获得优化的能谱参数:
For example, in some exemplary embodiments, the optimized energy spectrum parameters may be obtained by solving the following optimization function:

其中,“argmin”是一个数学术语,用于表示一个函数在其定义域中取得最小值的参数值(自变量的值)。具体地,在该优化函数中,表示:当取得最小值时的能谱参数{ck};Ne为基础能谱的总数量;k表示第k个基础能谱,1≤k≤Ne;ck表示第k个理论投影数据的权重系数,即表示第k个基础能谱的能谱参数,{ck}为一组能谱参数;sprjk为使用第k个基础能谱计算出的第k个理论投影数据;aprj为实际投影数据。例如,aprj可以为仅穿过能谱标定模体的第一校正投影数据。需要说明的是,aprj和sprjk两个数据为穿过的路径相同的射线入射到探测器上的投影数据。Among them, "argmin" is a mathematical term used to represent the parameter value (the value of the independent variable) of a function to achieve the minimum value in its domain. Specifically, in this optimization function, it means: The energy spectrum parameter {c k } when the minimum value is obtained; Ne is the total number of basic energy spectra; k represents the kth basic energy spectrum, 1≤k≤N e ; c k represents the weight coefficient of the kth theoretical projection data, that is, the energy spectrum parameter of the kth basic energy spectrum, {c k } is a set of energy spectrum parameters; sprj k is the kth theoretical projection data calculated using the kth basic energy spectrum; aprj is the actual projection data. For example, aprj can be the first correction projection data that only passes through the energy spectrum calibration phantom. It should be noted that aprj and sprj k are the projection data of rays that pass through the same path and are incident on the detector.

件,其表示第1~Ne个权重系数ck(即Ne个权重系数ck)之和近似等于1,此处的“近似等于”包括等于的情况,也包括在一定误差范围内的约等于的情况。 It means that the sum of the 1st to Ne weight coefficients c k (i.e. Ne weight coefficients c k ) is approximately equal to 1. Here, “approximately equal to” includes the case of being equal to and the case of being approximately equal to within a certain error range.

再例如,在一些示例性的实施例中,可以通过求解如下的优化函数,来获得优化的能谱参数:
For another example, in some exemplary embodiments, the optimized energy spectrum parameters may be obtained by solving the following optimization function:

其中,“argmin”是一个数学术语,用于表示一个函数在其定义域中取得最小值的参数值(自变量的值)。具体地,在该优化函数中,表示:当取得最小值时的能谱参数{ck};Ne为基础能谱的总数量;k表示第k个基础能谱,1≤k≤Ne;ck表示第k个理论投影数据的权重系数,即表示第k个基础能谱的能谱参数,{ck}为一组能谱参数;sprjj,k为使用第k个基础能谱计算出的与第j个类别的投影数据对应的第k个理论投影数据;aprjj为第j个类别的实际投影数据。Among them, "argmin" is a mathematical term used to represent the parameter value (the value of the independent variable) of a function to achieve the minimum value in its domain. Specifically, in this optimization function, it means: The energy spectrum parameter {c k } when the minimum value is obtained; Ne is the total number of basic energy spectra; k represents the kth basic energy spectrum, 1≤k≤N e ; c k represents the weight coefficient of the kth theoretical projection data, that is, the energy spectrum parameter of the kth basic energy spectrum, {c k } is a set of energy spectrum parameters; sprj j,k is the kth theoretical projection data corresponding to the jth category projection data calculated using the kth basic energy spectrum; aprj j is the actual projection data of the jth category.

件,其表示第1~Ne个权重系数ck(即Ne个权重系数ck)之和近似等于1,此处的“近似等于”包括等于的情况,也包括在一定误差范围内的约等于的情况。 It means that the sum of the 1st to Ne weight coefficients c k (i.e. Ne weight coefficients c k ) is approximately equal to 1. Here, “approximately equal to” includes the case of being equal to and the case of being approximately equal to within a certain error range.

在上述实施例中,在子步骤S1120中,可以通过求解上述优化函数,计算所述偏差取值为最小值时的Ne个优化权重系数{ck},将所述Ne个优化权重系数{ck}作为所述优化的能谱参数。In the above embodiment, in sub-step S1120, the above optimization function can be solved to calculate Ne optimization weight coefficients {c k } when the deviation is the minimum value, and the Ne optimization weight coefficients {c k } are used as the optimized energy spectrum parameters.

返回参照图9,在根据本公开的实施例的一些标定方法中,由于不需要迭代计算,所以,在子步骤S960中,可以将所述优化的能谱参数确定为能谱标定参数。Referring back to FIG. 9 , in some calibration methods according to embodiments of the present disclosure, since iterative calculation is not required, in sub-step S960 , the optimized energy spectrum parameters may be determined as energy spectrum calibration parameters.

返回参照图10,在根据本公开的实施例的另一些标定方法中,由于需要进行迭代计算,所以,在所述第一循环过程执行满足预设条件时,在子步骤S1040中,可以将该第一循环过程中最后一次获得的优化的能谱参数,确定为能谱标定参数。Referring back to FIG. 10 , in some other calibration methods according to the embodiments of the present disclosure, since iterative calculation is required, when the first cycle process satisfies the preset conditions, in sub-step S1040, the optimized energy spectrum parameters obtained for the last time in the first cycle process can be determined as the energy spectrum calibration parameters.

继续参照图10,在子步骤S1034中,可以根据所述Ne个优化权重系数和所述Ne个基础能谱,采用加权求和的方式计算得到所述能谱信息。Continuing to refer to FIG. 10 , in sub-step S1034 , the energy spectrum information may be calculated by weighted summation according to the Ne optimization weight coefficients and the Ne basic energy spectra.

例如,可以采用以下公式计算得到所述能谱信息:
For example, the energy spectrum information can be calculated using the following formula:

也就是说,可以将上述公式计算得到的所述能谱信息与实际投影数据对应。That is to say, the energy spectrum information calculated by the above formula can be matched with the actual projection data.

需要说明的是,在本公开的实施例中,所述第一循环过程的终止条件(即所述预设条件)可以包括以下条件中的至少一个:在所述第一循环过程中,相邻两次获取的能谱信息的偏差小于预设的阈值;和在所述第一循环过程中,迭代的次数达到预设的次数。It should be noted that, in an embodiment of the present disclosure, the termination condition of the first cycle process (i.e., the preset condition) may include at least one of the following conditions: in the first cycle process, the deviation of energy spectrum information acquired two adjacent times is less than a preset threshold; and in the first cycle process, the number of iterations reaches a preset number.

返回参照图4A至图4B,根据本公开的一些实施例的标定系统40可以包括:标定装置主体;设置于标定装置主体上的几何标定模体40和能谱标定模体60中的至少一个;驱动件430,驱动件430用于驱动几何标定模体40和能谱标定模体60中的至少一个运动;以及控制器450,控制器450被配置为:根据上述的标定方法,对扫描成像设备进行几何标定和/或能谱标定。Referring back to Figures 4A to 4B, the calibration system 40 according to some embodiments of the present disclosure may include: a calibration device body; at least one of a geometric calibration phantom 40 and an energy spectrum calibration phantom 60 disposed on the calibration device body; a driving member 430, the driving member 430 is used to drive at least one of the geometric calibration phantom 40 and the energy spectrum calibration phantom 60 to move; and a controller 450, the controller 450 is configured to: perform geometric calibration and/or energy spectrum calibration on the scanning imaging device according to the above-mentioned calibration method.

例如,所述标定装置主体可以包括:底座410;和连接于底座410上的旋转台420。或者,所述标定装置主体可以包括:底座410;连接于底座410上的升降台440;和连接于底座410上的旋转台420。For example, the calibration device body may include: a base 410; and a rotating platform 420 connected to the base 410. Alternatively, the calibration device body may include: a base 410; a lifting platform 440 connected to the base 410; and a rotating platform 420 connected to the base 410.

图12示意性示出了根据本公开的示例性实施例的标定系统的控制器的结构框图。FIG. 12 schematically shows a structural block diagram of a controller of a calibration system according to an exemplary embodiment of the present disclosure.

如图12所示,根据本公开实施例的标定系统的控制器450可以包括处理器1001,其可以根据存储在只读存储器(ROM)1002中的程序或者从存储部分1008加载到随机访问存储器(RAM)1003中的程序而执行各种适当的动作和处理。处理器1001例如可以包括通用微处理器(例如CPU)、指令集处理器和/或相关芯片组和/或专用微处理器(例如,专用集成电路(ASIC))等等。处理器1001还可以包括用于缓存用途的板载存储器。处理器1001可以包括用于执行根据本公开实施例的方法流程的不同动作的单一处理单元或者是多个处理单元。As shown in FIG. 12 , the controller 450 of the calibration system according to an embodiment of the present disclosure may include a processor 1001, which may perform various appropriate actions and processes according to a program stored in a read-only memory (ROM) 1002 or a program loaded from a storage portion 1008 into a random access memory (RAM) 1003. The processor 1001 may, for example, include a general-purpose microprocessor (e.g., a CPU), an instruction set processor and/or a related chipset and/or a dedicated microprocessor (e.g., an application-specific integrated circuit (ASIC)), etc. The processor 1001 may also include an onboard memory for caching purposes. The processor 1001 may include a single processing unit or multiple processing units for performing different actions of the method flow according to an embodiment of the present disclosure.

在RAM 1003中,存储有控制器450操作所需的各种程序和数据。处理器1001、ROM 1002以及RAM 1003通过总线1004彼此相连。处理器1001通过执行ROM 1002和/或RAM 1003中的程序来执行根据本公开实施例的方法流程的各种操作。需要注意,所述程序也可以存储在除ROM 1002和RAM 1003以外的一个或多个存储器中。处理器1001也可以通过执行存储在所述一个或多个存储器中的程序来执行根据本公开实施例的方法流程的各种操作。In RAM 1003, various programs and data required for the operation of controller 450 are stored. Processor 1001, ROM 1002 and RAM 1003 are connected to each other through bus 1004. Processor 1001 performs various operations of the method flow according to the embodiment of the present disclosure by executing the program in ROM 1002 and/or RAM 1003. It should be noted that the program can also be stored in one or more memories other than ROM 1002 and RAM 1003. Processor 1001 can also perform various operations of the method flow according to the embodiment of the present disclosure by executing the program stored in the one or more memories.

根据本公开的实施例,控制器450还可以包括输入/输出(I/O)接口1005,输入/输出(I/O)接口1005也连接至总线1004。控制器450还可以包括连接至I/O接口1005的以下部件中的一项或多项:包括键盘、鼠标等的输入部分1006;包括诸如阴极射线管(CRT)、液晶显示器(LCD)等以及扬声器等的输出部分1007;包括硬盘等的存储部分1008;以及包括诸如LAN卡、调制解调器等的网络接口卡的通信部分1009。通信部分1009经由诸如因特网的网络执行通信处理。驱动器1010也根据需要连接至I/O接口1005。可拆卸介质1011,诸如磁盘、光盘、磁光盘、半导体存储器等等,根据需要安装在驱动器1010上,以便于从其上读出的计算机程序根据需要被安装入存储部分1008。According to an embodiment of the present disclosure, the controller 450 may further include an input/output (I/O) interface 1005, which is also connected to the bus 1004. The controller 450 may further include one or more of the following components connected to the I/O interface 1005: an input portion 1006 including a keyboard, a mouse, etc.; an output portion 1007 including a cathode ray tube (CRT), a liquid crystal display (LCD), etc., and a speaker, etc.; a storage portion 1008 including a hard disk, etc.; and a communication portion 1009 including a network interface card such as a LAN card, a modem, etc. The communication portion 1009 performs communication processing via a network such as the Internet. A drive 1010 is also connected to the I/O interface 1005 as needed. A removable medium 1011, such as a magnetic disk, an optical disk, a magneto-optical disk, a semiconductor memory, etc., is installed on the drive 1010 as needed, so that a computer program read therefrom is installed into the storage portion 1008 as needed.

本公开还提供了一种计算机可读存储介质,该计算机可读存储介质可以是上述实施例中描述的设备/装置/系统中所包含的;也可以是单独存在,而未装配入该设备/装置/系统中。上述计算机可读存储介质承载有一个或者多个程序,当上述一个或者多个程序被执行时,实现根据本公开实施例的方法。The present disclosure also provides a computer-readable storage medium, which may be included in the device/apparatus/system described in the above embodiments; or may exist independently without being assembled into the device/apparatus/system. The above computer-readable storage medium carries one or more programs, and when the above one or more programs are executed, the method according to the embodiment of the present disclosure is implemented.

根据本公开的实施例,计算机可读存储介质可以是非易失性的计算机可读存储介质,例如可以包括但不限于:便携式计算机磁盘、硬盘、随机访问存储器(RAM)、只读存储器(ROM)、可擦式可编程只读存储器(EPROM或闪存)、便携式紧凑磁盘只读存储器(CD-ROM)、光存储器件、磁存储器件、或者上述的任意合适的组合。在本公开中,计算机可读存储介质可以是任何包含或存储程序的有形介质,该程序可以被指令执行系统、装置或者器件使用或者与其结合使用。例如,根据本公开的实施例,计算机可读存储介质可以包括上文描述的ROM 1002和/或RAM 1003和/或ROM 1002和RAM 1003以外的一个或多个存储器。According to an embodiment of the present disclosure, a computer-readable storage medium may be a non-volatile computer-readable storage medium, such as but not limited to: a portable computer disk, a hard disk, a random access memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), a portable compact disk read-only memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the above. In the present disclosure, a computer-readable storage medium may be any tangible medium containing or storing a program that may be used by or in conjunction with an instruction execution system, apparatus, or device. For example, according to an embodiment of the present disclosure, a computer-readable storage medium may include the ROM 1002 and/or RAM 1003 described above and/or one or more memories other than ROM 1002 and RAM 1003.

需要说明的是,在上述实施例中,以具有分布式射线源的静态CT扫描成像设备为例,对标定方法进行了描述,但是,本公开的实施例不局限于此。在本公开的另一些示例性的实施例中,所述标定系统和标定方法也可以对单靶点射线源的螺旋CT设备进行能谱标定,在标定过程中,射线源和探测器处于静止状态。It should be noted that in the above embodiments, the calibration method is described by taking a static CT scanning imaging device with a distributed radiation source as an example, but the embodiments of the present disclosure are not limited thereto. In other exemplary embodiments of the present disclosure, the calibration system and calibration method can also perform energy spectrum calibration on a spiral CT device with a single target radiation source, and during the calibration process, the radiation source and the detector are in a static state.

还需要说明的是,本公开的实施例也可以对单/多视角X射线成像设备进行能谱标定。例如,在一些实施例中,射线源的靶点数量可以为Ns=1,虽然单/多视角X射线成像设备自身非CT设备,无法对被扫描物进行CT成像,但是单靶点出束时,标定装置旋转采集的数据满足CT成像的数据完备性要求,也可以进行CT重建,从而也适用于上面描述的能谱标定流程。It should also be noted that the embodiments of the present disclosure can also perform energy spectrum calibration on single/multi-view X-ray imaging devices. For example, in some embodiments, the number of target points of the ray source can be Ns = 1. Although the single/multi-view X-ray imaging device itself is not a CT device and cannot perform CT imaging on the scanned object, when a single target point emits a beam, the data collected by the calibration device in rotation meets the data completeness requirements of CT imaging, and CT reconstruction can also be performed, so it is also applicable to the energy spectrum calibration process described above.

根据本公开的实施例,可以以一种或多种程序设计语言的任意组合来编写用于执行本公开实施例提供的计算机程序的程序代码,具体地,可以利用高级过程和/或面向对象的编程语言、和/或汇编/机器语言来实施这些计算程序。程序设计语言包括但不限于诸如Java,C++,python,“C”语言或类似的程序设计语言。程序代码可以完全地在用户计算设备上执行、部分地在用户设备上执行、部分在远程计算设备上执行、或者完全在远程计算设备或服务器上执行。在涉及远程计算设备的情形中,远程计算设备可以通过任意种类的网络,包括局域网(LAN)或广域网(WAN),连接到用户计算设备,或者,可以连接到外部计算设备(例如利用因特网服务提供商来通过因特网连接)。According to an embodiment of the present disclosure, the program code for executing the computer program provided by the embodiment of the present disclosure can be written in any combination of one or more programming languages. Specifically, these computing programs can be implemented using high-level process and/or object-oriented programming languages, and/or assembly/machine languages. Programming languages include, but are not limited to, Java, C++, python, "C" language or similar programming languages. The program code can be executed entirely on the user computing device, partially on the user device, partially on the remote computing device, or entirely on the remote computing device or server. In the case of a remote computing device, the remote computing device can be connected to the user computing device through any type of network, including a local area network (LAN) or a wide area network (WAN), or can be connected to an external computing device (for example, using an Internet service provider to connect through the Internet).

附图中的流程图和框图,图示了按照本公开各种实施例的系统、方法和计算机程序产品的可能实现的体系架构、功能和操作。在这点上,流程图或框图中的每个方框可以代表一个模块、程序段、或代码的一部分,上述模块、程序段、或代码的一部分包含一个或多个用于实现规定的逻辑功能的可执行指令。也应当注意,在有些作为替换的实现中,方框中所标注的功能也可以以不同于附图中所标注的顺序发生。例如,两个接连地表示的方框实际上可以基本并行地执行,它们有时也可以按相反的顺序执行,这依所涉及的功能而定。也要注意的是,框图或流程图中的每个方框、以及框图或流程图中的方框的组合,可以用执行规定的功能或操作的专用的基于硬件的系统来实现,或者可以用专用硬件与计算机指令的组合来实现。The flow charts and block diagrams in the accompanying drawings illustrate the possible architecture, functions and operations of the systems, methods and computer program products according to various embodiments of the present disclosure. In this regard, each box in the flow chart or block diagram can represent a module, a program segment, or a part of a code, and the above-mentioned module, program segment, or a part of a code contains one or more executable instructions for realizing the specified logical function. It should also be noted that in some alternative implementations, the functions marked in the box can also occur in a different order from the order marked in the accompanying drawings. For example, two boxes represented in succession can actually be executed substantially in parallel, and they can sometimes be executed in the opposite order, depending on the functions involved. It should also be noted that each box in the block diagram or flow chart, and the combination of the boxes in the block diagram or flow chart can be implemented with a dedicated hardware-based system that performs a specified function or operation, or can be implemented with a combination of dedicated hardware and computer instructions.

在本说明书的描述中,参考术语“一个实施例”、“一些实施例”、“示意性实施例”、“示例”、“具体示例”、或“一些示例”等的描述意指结合该实施例或示例描述的具体特征、结构、材料或者特点包含于本公开的至少一个实施例或示例中。在本说明书中,对上述术语的示意性表述不一定指的是相同的实施例或示例。而且,描述的具体特征、结构、材料或者特点可以在任何的一个或多个实施例或示例中以合适的方式结合。In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "illustrative embodiments", "examples", "specific examples", or "some examples" means that the specific features, structures, materials, or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present disclosure. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials, or characteristics described may be combined in any one or more embodiments or examples in a suitable manner.

尽管已经示出和描述了本公开的实施例,本领域的普通技术人员可以理解:在不脱离本公开的原理和宗旨的情况下可以对这些实施例进行多种变化、修改、替换和变型,本公开的范围由权利要求及其等同物限定。本领域技术人员可以理解,本公开的各个实施例和/或权利要求中记载的特征可以进行多种组合或/或结合,即使这样的组合或结合没有明确记载于本公开中。特别地,在不脱离本公开精神和教导的情况下,本公开的各个实施例和/或权利要求中记载的特征可以进行多种组合和/或结合。所有这些组合和/或结合均落入本公开的范围。Although the embodiments of the present disclosure have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations may be made to these embodiments without departing from the principles and purpose of the present disclosure, and the scope of the present disclosure is defined by the claims and their equivalents. It will be understood by those skilled in the art that the features described in the various embodiments of the present disclosure and/or the claims may be combined in various combinations and/or combinations, even if such combinations or combinations are not explicitly described in the present disclosure. In particular, the features described in the various embodiments of the present disclosure and/or the claims may be combined in various combinations and/or combinations without departing from the spirit and teachings of the present disclosure. All of these combinations and/or combinations fall within the scope of the present disclosure.

Claims (22)

一种用于标定扫描成像设备的标定方法,所述扫描成像设备包括用于发出射线的射线源和用于接收射线的探测器,在标定过程中,几何标定模体或能谱标定模体位于所述射线形成的扫描区域中,其特征在于,所述标定方法包括:A calibration method for calibrating a scanning imaging device, wherein the scanning imaging device comprises a ray source for emitting rays and a detector for receiving rays. During the calibration process, a geometric calibration phantom or an energy spectrum calibration phantom is located in a scanning area formed by the rays. The calibration method comprises: 在几何标定模体位于所述射线形成的扫描区域中的情况下,执行几何标定步骤,其中,所述几何标定步骤包括:通过所述探测器采集经过所述扫描区域的射线,获得与所述几何标定模体相关的探测器数据;利用所述探测器数据,对射线源参数和探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,并将所述优化的射线源参数和优化的探测器参数确定为几何标定参数,其中,所述射线源参数用于表示所述射线源在标定系统中的位置,所述探测器参数用于表示所述探测器在所述标定系统中的位置;In the case where the geometric calibration phantom is located in the scanning area formed by the rays, a geometric calibration step is performed, wherein the geometric calibration step includes: collecting rays passing through the scanning area by the detector to obtain detector data related to the geometric calibration phantom; using the detector data, calibrating ray source parameters and detector parameters to obtain optimized ray source parameters and optimized detector parameters, and determining the optimized ray source parameters and optimized detector parameters as geometric calibration parameters, wherein the ray source parameters are used to represent the position of the ray source in the calibration system, and the detector parameters are used to represent the position of the detector in the calibration system; 在能谱标定模体位于所述射线形成的扫描区域中的情况下,根据所述几何标定参数,确定所述射线源、所述能谱标定模体和所述探测器之间的相对位置,以获取所述射线源、所述能谱标定模体和所述探测器之间的几何关系;以及In a case where the energy spectrum calibration phantom is located in a scanning area formed by the radiation, determining the relative positions among the radiation source, the energy spectrum calibration phantom and the detector according to the geometric calibration parameters to obtain a geometric relationship among the radiation source, the energy spectrum calibration phantom and the detector; and 在能谱标定模体位于所述射线形成的扫描区域中的情况下,执行能谱标定步骤,其中,所述能谱标定步骤包括:通过所述探测器采集经过所述扫描区域的射线,获取与所述能谱模体相关的实际投影数据;利用与所述能谱模体相关的实际投影数据,根据所述几何关系和所述能谱标定模体的物理属性,对能谱参数进行标定,以获取优化的能谱参数,并将所述优化的能谱参数确定为能谱标定参数。When the energy spectrum calibration phantom is located in the scanning area formed by the rays, the energy spectrum calibration step is performed, wherein the energy spectrum calibration step includes: collecting the rays passing through the scanning area through the detector to obtain actual projection data related to the energy spectrum phantom; using the actual projection data related to the energy spectrum phantom, according to the geometric relationship and the physical properties of the energy spectrum calibration phantom, calibrating the energy spectrum parameters to obtain optimized energy spectrum parameters, and determining the optimized energy spectrum parameters as energy spectrum calibration parameters. 一种用于标定扫描成像设备的标定方法,所述扫描成像设备包括用于发出射线的射线源和用于接收射线的探测器,在标定过程中,几何标定模体和能谱标定模体两者均位于所述射线形成的扫描区域中,其特征在于,所述标定方法包括:A calibration method for calibrating a scanning imaging device, the scanning imaging device comprising a ray source for emitting rays and a detector for receiving rays, during the calibration process, both a geometric calibration phantom and an energy spectrum calibration phantom are located in a scanning area formed by the rays, characterized in that the calibration method comprises: 在几何标定模体和能谱标定模体两者均位于所述射线形成的扫描区域中的情况下,执行几何标定步骤和能谱标定步骤,其中,所述执行几何标定步骤和能谱标定步骤包括:In the case where both the geometric calibration phantom and the energy spectrum calibration phantom are located in the scanning area formed by the rays, a geometric calibration step and an energy spectrum calibration step are performed, wherein the performing of the geometric calibration step and the energy spectrum calibration step comprises: 通过所述探测器采集经过所述扫描区域的射线,获取与所述几何标定模体和所述能谱标定模体均相关的探测器数据;Collecting rays passing through the scanning area by the detector to obtain detector data related to both the geometric calibration phantom and the energy spectrum calibration phantom; 利用所述探测器数据,对射线源参数和探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,并将所述优化的射线源参数和优化的探测器参数确定为几何标定参数,其中,所述射线源参数用于表示所述射线源在标定系统中的位置,所述探测器参数用于表示所述探测器在所述标定系统中的位置;Calibrate the ray source parameters and the detector parameters by using the detector data to obtain optimized ray source parameters and optimized detector parameters, and determine the optimized ray source parameters and optimized detector parameters as geometric calibration parameters, wherein the ray source parameters are used to represent the position of the ray source in the calibration system, and the detector parameters are used to represent the position of the detector in the calibration system; 根据所述几何标定参数,确定所述射线源、所述能谱标定模体和所述探测器之间的相对位置,以获取所述射线源、所述能谱标定模体和所述探测器之间的几何关系;以及Determining the relative positions of the ray source, the energy spectrum calibration phantom, and the detector according to the geometric calibration parameters to obtain a geometric relationship between the ray source, the energy spectrum calibration phantom, and the detector; and 利用所述探测器数据,根据所述几何关系和所述能谱标定模体的物理属性,对能谱参数进行标定,以获取优化的能谱参数,并将所述优化的能谱参数确定为能谱标定参数。The detector data is used to calibrate the energy spectrum parameters according to the geometric relationship and the physical properties of the energy spectrum calibration phantom to obtain optimized energy spectrum parameters, and the optimized energy spectrum parameters are determined as energy spectrum calibration parameters. 根据权利要求1或2所述的方法,其中,所述探测器数据包括所述射线经过所述扫描区域中的几何标定模体后在所述探测器上的实际投影位置;The method according to claim 1 or 2, wherein the detector data comprises an actual projection position of the ray on the detector after the ray passes through a geometric calibration phantom in the scanning area; 所述对射线源参数和探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,并将所述优化的射线源参数和优化的探测器参数确定为几何标定参数,具体包括:The calibrating of the ray source parameters and the detector parameters to obtain optimized ray source parameters and optimized detector parameters, and determining the optimized ray source parameters and optimized detector parameters as geometric calibration parameters, specifically includes: 获取初始的射线源参数和初始的探测器参数,其中,所述射线源参数用于表示所述射线源在标定系统中的位置,所述探测器参数用于表示所述探测器在所述标定系统中的位置;Acquire initial ray source parameters and initial detector parameters, wherein the ray source parameters are used to indicate the position of the ray source in the calibration system, and the detector parameters are used to indicate the position of the detector in the calibration system; 根据初始的射线源参数、初始的探测器参数以及所述几何标定模体相对于所述射线源和所述探测器的位置关系,通过几何计算获得所述几何标定模体在所述探测器上的理论投影位置;According to initial ray source parameters, initial detector parameters and the positional relationship of the geometric calibration phantom relative to the ray source and the detector, a theoretical projection position of the geometric calibration phantom on the detector is obtained by geometric calculation; 根据所述实际投影位置和所述理论投影位置,对所述射线源参数和所述探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数;以及Calibrate the ray source parameters and the detector parameters according to the actual projection position and the theoretical projection position to obtain optimized ray source parameters and optimized detector parameters; and 将所述优化的射线源参数和优化的探测器参数确定为几何标定参数。The optimized ray source parameters and the optimized detector parameters are determined as geometric calibration parameters. 根据权利要求3所述的方法,其中,根据所述实际投影位置和所述理论投影位置,对所述射线源参数和所述探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,包括:The method according to claim 3, wherein the ray source parameters and the detector parameters are calibrated according to the actual projection position and the theoretical projection position to obtain optimized ray source parameters and optimized detector parameters, comprising: 构建所述实际投影位置和所述理论投影位置之间的偏差关于射线源参数和探测器参数的优化函数,在所述优化函数中,所述偏差为因变量,所述射线源参数和所述探测器参数为自变量。An optimization function of the deviation between the actual projection position and the theoretical projection position with respect to ray source parameters and detector parameters is constructed, in which the deviation is a dependent variable, and the ray source parameters and the detector parameters are independent variables. 根据权利要求4所述的方法,其中,根据所述实际投影位置和所述理论投影位置,对所述射线源参数和所述探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,还包括:The method according to claim 4, wherein the ray source parameters and the detector parameters are calibrated according to the actual projection position and the theoretical projection position to obtain optimized ray source parameters and optimized detector parameters, further comprising: 根据所述优化函数,将所述偏差取值最小值时对应的射线源参数和探测器参数确定为优化的射线源参数和优化的探测器参数,将所述优化的射线源参数和优化的探测器参数确定为几何标定参数。According to the optimization function, the ray source parameters and the detector parameters corresponding to the minimum value of the deviation are determined as optimized ray source parameters and optimized detector parameters, and the optimized ray source parameters and optimized detector parameters are determined as geometric calibration parameters. 根据权利要求3所述的方法,其中,所述射线源包括Ns个靶点,所述Ns个靶点沿第一方向间隔分布,其中,Ns为大于等于2的正整数;The method according to claim 3, wherein the ray source comprises N s target points, and the N s target points are spaced apart along the first direction, wherein N s is a positive integer greater than or equal to 2; 根据所述实际投影位置和所述理论投影位置,对所述射线源参数和所述探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,包括:Calibrate the ray source parameters and the detector parameters according to the actual projection position and the theoretical projection position to obtain optimized ray source parameters and optimized detector parameters, including: 构建优化函数,所述优化函数包括投影位置约束项和靶点距离约束项,Constructing an optimization function, wherein the optimization function includes a projection position constraint term and a target distance constraint term, 其中,所述投影位置约束项为所述实际投影位置和所述理论投影位置之间的偏差关于射线源参数和探测器参数的第一函数;所述靶点距离约束项为相邻的两个靶点之间的实际距离和理论距离之间的偏差关于射线源参数和探测器参数的第二函数。Among them, the projection position constraint term is a first function of the deviation between the actual projection position and the theoretical projection position with respect to the ray source parameters and the detector parameters; the target point distance constraint term is a second function of the deviation between the actual distance and the theoretical distance between two adjacent target points with respect to the ray source parameters and the detector parameters. 根据权利要求6所述的方法,其中,在所述优化函数中,所述投影位置约束项具有第一权重值,所述靶点距离约束项具有第二权重值。The method according to claim 6, wherein, in the optimization function, the projection position constraint term has a first weight value, and the target distance constraint term has a second weight value. 根据权利要求6或7所述的方法,其中,根据所述实际投影位置和所述理论投影位置,对所述射线源参数和所述探测器参数进行标定,以获取优化的射线源参数和优化的探测器参数,还包括:The method according to claim 6 or 7, wherein the ray source parameters and the detector parameters are calibrated according to the actual projection position and the theoretical projection position to obtain optimized ray source parameters and optimized detector parameters, further comprising: 根据所述优化函数,将所述实际投影位置和所述理论投影位置之间的偏差和相邻的两个靶点之间的实际距离和理论距离之间的偏差的加权求和取值最小值时对应的射线源参数和探测器参数确定为优化的射线源参数和优化的探测器参数,将所述优化的射线源参数和优化的探测器参数确定为几何标定参数。According to the optimization function, the ray source parameters and detector parameters corresponding to the minimum value of the weighted sum of the deviation between the actual projection position and the theoretical projection position and the deviation between the actual distance and the theoretical distance between two adjacent target points are determined as optimized ray source parameters and optimized detector parameters, and the optimized ray source parameters and optimized detector parameters are determined as geometric calibration parameters. 根据权利要求1-8中任一项所述的方法,其中,所述根据所述几何关系和所述能谱标定模体的物理属性,对能谱参数进行标定,以获取优化的能谱参数,并将所述优化的能谱参数确定为能谱标定参数,具体包括:The method according to any one of claims 1 to 8, wherein the calibrating the energy spectrum parameters according to the geometric relationship and the physical properties of the energy spectrum calibration phantom to obtain optimized energy spectrum parameters, and determining the optimized energy spectrum parameters as energy spectrum calibration parameters, specifically comprises: 获取所述能谱标定模体的物理属性,其中,所述物理属性是根据所述能谱标定模体的组成材料预先确定的;Acquiring physical properties of the energy spectrum calibration phantom, wherein the physical properties are predetermined according to constituent materials of the energy spectrum calibration phantom; 基于所述能谱标定模体的物理属性和所述几何关系,使用预定的多个基础能谱计算理论投影数据;Based on the physical properties of the energy spectrum calibration phantom and the geometric relationship, using a predetermined plurality of basic energy spectra to calculate theoretical projection data; 根据所述理论投影数据和所述实际投影数据,对能谱参数进行标定,以获取优化的能谱参数;以及Calibrate energy spectrum parameters according to the theoretical projection data and the actual projection data to obtain optimized energy spectrum parameters; and 将所述优化的能谱参数确定为能谱标定参数。The optimized energy spectrum parameters are determined as energy spectrum calibration parameters. 根据权利要求1-8中任一项所述的方法,其中,所述根据所述几何关系和所述能谱标定模体的物理属性,对能谱参数进行标定,以获取优化的能谱参数,并将所述优化的能谱参数确定为能谱标定参数,具体包括:The method according to any one of claims 1 to 8, wherein the calibrating the energy spectrum parameters according to the geometric relationship and the physical properties of the energy spectrum calibration phantom to obtain optimized energy spectrum parameters, and determining the optimized energy spectrum parameters as energy spectrum calibration parameters, specifically comprises: 执行循环过程直至满足预设条件,所述第一循环过程包括:The loop process is executed until a preset condition is met, wherein the first loop process includes: 根据能谱信息,对所述能谱标定模体进行图像重建,根据所述图像重建的结果获取所述能谱标定模体的物理属性;Performing image reconstruction on the energy spectrum calibration phantom according to the energy spectrum information, and obtaining physical properties of the energy spectrum calibration phantom according to a result of the image reconstruction; 基于所述能谱标定模体的物理属性和所述几何关系,使用预定的多个基础能谱计算理论投影数据;Based on the physical properties of the energy spectrum calibration phantom and the geometric relationship, using a predetermined plurality of basic energy spectra to calculate theoretical projection data; 根据所述理论投影数据和所述实际投影数据,对能谱参数进行标定,以获取优化的能谱参数;和Calibrate energy spectrum parameters according to the theoretical projection data and the actual projection data to obtain optimized energy spectrum parameters; and 基于所述优化的能谱参数,获取能谱信息;以及Based on the optimized energy spectrum parameters, acquiring energy spectrum information; and 将所述第一循环过程中最后一次获得的优化的能谱参数,确定为能谱标定参数。The optimized energy spectrum parameters obtained for the last time during the first cycle are determined as energy spectrum calibration parameters. 根据权利要求9或10所述的方法,其中,所述根据所述理论投影数据和所述实际投影数据,对能谱参数进行标定,以获取优化的能谱参数,包括:The method according to claim 9 or 10, wherein the calibrating the energy spectrum parameters according to the theoretical projection data and the actual projection data to obtain the optimized energy spectrum parameters comprises: 构建所述理论投影数据和所述实际投影数据之间的偏差关于能谱参数的优化函数;以及constructing an optimization function of the deviation between the theoretical projection data and the actual projection data with respect to energy spectrum parameters; and 根据所述优化函数,对能谱参数进行标定,以获取优化的能谱参数。According to the optimization function, the energy spectrum parameters are calibrated to obtain optimized energy spectrum parameters. 根据权利要求1-11中任一项所述的方法,其中,所述几何标定模体包括至少一个金属丝;或者,The method according to any one of claims 1 to 11, wherein the geometric calibration phantom comprises at least one metal wire; or 所述几何标定模体包括多个金属丝,所述多个金属丝以彼此不同的半径和/或彼此不同的角度分布在所述旋转台上。The geometric calibration phantom includes a plurality of metal wires, and the plurality of metal wires are distributed on the rotating platform with different radii and/or different angles. 根据权利要求1-12中任一项所述的方法,其中,所述能谱标定模体包括分别由多种材料构成的多个部分,所述多种材料中的任意两者的以下至少一种属性不相同:密度,原子序数。The method according to any one of claims 1 to 12, wherein the energy spectrum calibration phantom comprises a plurality of parts respectively composed of a plurality of materials, and at least one of the following properties of any two of the plurality of materials is different: density, atomic number. 根据权利要求1-13中任一项所述的方法,其中,所述标定系统包括旋转台,所述几何标定模体和所述能谱标定模体中的至少一个位于所述旋转台上;The method according to any one of claims 1 to 13, wherein the calibration system comprises a rotating table, and at least one of the geometric calibration phantom and the energy spectrum calibration phantom is located on the rotating table; 所述通过所述探测器采集经过所述扫描区域的射线,获得探测器数据,包括:The step of collecting the rays passing through the scanning area by the detector to obtain detector data includes: 控制所述射线源发出射线;Controlling the ray source to emit rays; 控制所述旋转台旋转,以带动所述几何标定模体和所述能谱标定模体中的至少一个旋转m圈,其中,m为大于等于1的正整数;以及Controlling the rotating stage to rotate so as to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to rotate m times, wherein m is a positive integer greater than or equal to 1; and 在所述几何标定模体和所述能谱标定模体中的至少一个旋转m圈的过程中,所述探测器采集从所述射线源发出且经过所述扫描区域的射线。During the process in which at least one of the geometric calibration phantom and the energy spectrum calibration phantom rotates m circles, the detector collects rays emitted from the ray source and passing through the scanning area. 根据权利要求1-14中任一项所述的方法,其中,所述标定系统包括升降台,所述几何标定模体和所述能谱标定模体中的至少一个位于所述升降台上;The method according to any one of claims 1 to 14, wherein the calibration system comprises a lifting platform, and at least one of the geometric calibration phantom and the energy spectrum calibration phantom is located on the lifting platform; 所述通过所述探测器采集经过所述扫描区域的射线,获得探测器数据,包括:The step of collecting the rays passing through the scanning area by the detector to obtain detector data includes: 控制所述射线源发出射线;以及controlling the radiation source to emit radiation; and 控制所述升降台升降,以带动所述几何标定模体和所述能谱标定模体中的至少一个升降。The lifting platform is controlled to move up and down, so as to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to move up and down. 根据权利要求1-15中任一项所述的方法,其中,所述射线源包括Ns个靶点,所述Ns个靶点沿第一方向间隔分布,其中,Ns为大于等于2的正整数;The method according to any one of claims 1 to 15, wherein the ray source comprises N s target points, and the N s target points are spaced apart along the first direction, wherein N s is a positive integer greater than or equal to 2; 所述通过所述探测器采集经过所述扫描区域的射线,获得探测器数据,包括:The step of collecting the rays passing through the scanning area by the detector to obtain detector data includes: 控制所述Ns个靶点按照设定顺序发出射线;以及Controlling the N s target points to emit rays in a set order; and 在所述Ns个靶点按照设定顺序发出射线的过程中,所述探测器采集从所述射线源发出且经过所述扫描区域的射线。In the process that the Ns target points emit radiation in a set order, the detector collects radiation emitted from the radiation source and passing through the scanning area. 根据权利要求1-13中任一项所述的方法,其中,所述标定系统包括旋转台,所述几何标定模体和所述能谱标定模体中的至少一个位于所述旋转台上;所述射线源包括Ns个靶点,所述Ns个靶点沿第一方向间隔分布,其中,Ns为大于等于2的正整数;The method according to any one of claims 1 to 13, wherein the calibration system comprises a rotating table, and at least one of the geometric calibration phantom and the energy spectrum calibration phantom is located on the rotating table; the ray source comprises N s target points, and the N s target points are spaced apart along the first direction, wherein N s is a positive integer greater than or equal to 2; 所述通过所述探测器采集经过所述扫描区域的射线,获得探测器数据,包括:The step of collecting the rays passing through the scanning area by the detector to obtain detector data includes: 控制所述Ns个靶点按照设定顺序发出射线;Controlling the N s target points to emit rays in a set order; 控制所述旋转台旋转,以带动所述几何标定模体和所述能谱标定模体中的至少一个旋转m圈,其中,m为大于等于1的正整数;以及Controlling the rotating stage to rotate so as to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to rotate m times, wherein m is a positive integer greater than or equal to 1; and 在所述Ns个靶点按照设定顺序发出射线和所述几何标定模体和所述能谱标定模体中的至少一个旋转m圈的过程中,所述探测器采集从所述射线源发出且经过所述扫描区域的射线。In the process that the Ns target points emit radiation in a set order and at least one of the geometric calibration phantom and the energy spectrum calibration phantom rotates m circles, the detector collects radiation emitted from the radiation source and passing through the scanning area. 根据权利要求1所述的方法,其中,在确定所述射线源、所述能谱标定模体和所述探测器之间的相对位置之前,所述方法还包括:标定承载所述能谱标定模体的标定装置主体相对于所述射线源和所述探测器的相对位置。According to the method of claim 1, before determining the relative positions among the ray source, the energy spectrum calibration phantom and the detector, the method further comprises: calibrating the relative position of a calibration device body carrying the energy spectrum calibration phantom relative to the ray source and the detector. 根据权利要求2所述的方法,其中,所述根据所述几何关系和所述能谱标定模体的物理属性,对能谱参数进行标定,以获取优化的能谱参数,并将所述优化的能谱参数确定为能谱标定参数,具体包括:The method according to claim 2, wherein the step of calibrating the energy spectrum parameters according to the geometric relationship and the physical properties of the energy spectrum calibration phantom to obtain optimized energy spectrum parameters, and determining the optimized energy spectrum parameters as energy spectrum calibration parameters, specifically comprises: 执行循环过程直至满足预设条件,所述第一循环过程包括:The loop process is executed until a preset condition is met, wherein the first loop process includes: 根据能谱信息,对所述几何标定模体和所述能谱标定模体进行图像重建,以获取第一重建图像;对所述第一重建图像进行分割处理,分割出所述几何标定模体和所述能谱标定模体,以获取第二重建图像;和根据所述第二重建图像获取所述能谱标定模体的物理属性;According to the energy spectrum information, image reconstruction is performed on the geometric calibration phantom and the energy spectrum calibration phantom to obtain a first reconstructed image; segmentation is performed on the first reconstructed image to segment the geometric calibration phantom and the energy spectrum calibration phantom to obtain a second reconstructed image; and physical properties of the energy spectrum calibration phantom are obtained according to the second reconstructed image; 基于所述能谱标定模体的物理属性和所述几何关系,使用预定的多个基础能谱计算理论投影数据;Based on the physical properties of the energy spectrum calibration phantom and the geometric relationship, using a predetermined plurality of basic energy spectra to calculate theoretical projection data; 根据所述理论投影数据和所述实际投影数据,对能谱参数进行标定,以获取优化的能谱参数;和Calibrate energy spectrum parameters according to the theoretical projection data and the actual projection data to obtain optimized energy spectrum parameters; and 基于所述优化的能谱参数,获取能谱信息;以及Based on the optimized energy spectrum parameters, acquiring energy spectrum information; and 将所述第一循环过程中最后一次获得的优化的能谱参数,确定为能谱标定参数。The optimized energy spectrum parameters obtained for the last time during the first cycle are determined as energy spectrum calibration parameters. 一种用于标定扫描成像设备的标定系统,其中,所述标定系统包括:A calibration system for calibrating a scanning imaging device, wherein the calibration system comprises: 标定装置主体;Calibration device body; 设置于所述标定装置主体上的几何标定模体和能谱标定模体中的至少一个;At least one of a geometric calibration phantom and an energy spectrum calibration phantom disposed on the calibration device body; 驱动件,所述驱动件用于驱动所述几何标定模体和所述能谱标定模体中的至少一个运动;以及a driving member, the driving member being used to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to move; and 控制器,所述控制器被配置为根据如权利要求1-19中任一项所述的标定方法,对扫描成像设备进行标定。A controller, wherein the controller is configured to calibrate the scanning imaging device according to the calibration method according to any one of claims 1-19. 一种用于标定扫描成像设备的标定系统,其中,所述标定系统包括:A calibration system for calibrating a scanning imaging device, wherein the calibration system comprises: 底座;Base; 连接于所述底座上的旋转台;a rotating table connected to the base; 设置于所述旋转台上的几何标定模体和能谱标定模体中的至少一个,所述几何标定模体和所述能谱标定模体中的至少一个位于所述旋转台上;以及At least one of a geometric calibration phantom and an energy spectrum calibration phantom disposed on the rotating table, wherein at least one of the geometric calibration phantom and the energy spectrum calibration phantom is located on the rotating table; and 驱动件,所述驱动件用于驱动所述旋转台旋转,以带动所述几何标定模体和所述能谱标定模体中的至少一个旋转,a driving member, the driving member being used to drive the rotating table to rotate, so as to drive at least one of the geometric calibration phantom and the energy spectrum calibration phantom to rotate, 其中,所述几何标定模体包括至少一个金属丝;或者,所述几何标定模体包括多个金属丝,所述多个金属丝以彼此不同的半径和/或彼此不同的角度分布在所述旋转台上;和/或,Wherein, the geometric calibration phantom includes at least one metal wire; or, the geometric calibration phantom includes a plurality of metal wires, and the plurality of metal wires are distributed on the rotating table with different radii and/or different angles from each other; and/or, 所述能谱标定模体包括分别由多种材料构成的多个部分,所述多种材料中的任意两者的以下至少一种属性不相同:密度,原子序数。The energy spectrum calibration phantom includes a plurality of parts respectively made of a plurality of materials, and at least one of the following properties of any two of the plurality of materials is different: density, atomic number. 根据权利要求21所述的系统,其中,所述标定系统还包括:升降台,所述升降台连接于所述底座上,所述旋转台设置于所述升降台上。The system according to claim 21, wherein the calibration system further comprises: a lifting platform, the lifting platform is connected to the base, and the rotating platform is arranged on the lifting platform.
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