WO2025039396A1 - Calculation method and apparatus for fractional flow reserve (ffr) of virtual stent, and device and medium - Google Patents

Abstract

A calculation method and apparatus for a fractional flow reserve (FFR) of a virtual stent, and a device and a medium. The calculation method comprises: in response to a selection operation for a target blood vessel segment, displaying the selected target blood vessel segment in an interaction interface (S110); and in response to an adjustment operation for a virtual stent that is implanted into the target blood vessel segment, displaying, in the interaction interface, an FFR of the virtual stent after being adjusted (S120).

Description

Virtual stent blood flow reserve fraction FFR calculation method, device, equipment and medium

This application claims the priority of the Chinese patent application filed with the China Patent Office on August 22, 2023, with application number 202311062888.7, the entire contents of which are incorporated by reference into this application.

Technical Field

The present application relates to the field of data processing technology, and for example, to a method, device, equipment and medium for calculating the blood flow reserve fraction (FFR) of a virtual stent.

Background Art

FFR is a wire-free Fractional Flow Reserve analysis method based on coronary angiography images.

In the case of virtual stent implantation, the FFR determination system cannot determine the real-time changing FFR, resulting in the problem that the FFR cannot be updated and displayed in real time.

Summary of the invention

The present application provides a virtual stent FFR calculation method, device, equipment and medium to achieve real-time display of the FFR adjusted by the virtual stent in the target blood vessel segment in an interactive interface, thereby improving the timeliness of FFR.

According to one aspect of the present application, a virtual stent FFR calculation method is provided, comprising:

In response to a selection operation on a target blood vessel segment, displaying the selected target blood vessel segment in an interactive interface;

In response to the adjustment operation of the virtual stent implanted in the target blood vessel segment, the FFR of the virtual stent after adjustment is displayed in the interactive interface.

According to another aspect of the present application, a virtual stent FFR calculation device is provided, comprising:

a target blood vessel segment selection module, configured to display the selected target blood vessel segment in an interactive interface in response to a selection operation on the target blood vessel segment;

The FFR display module is configured to display the FFR after the virtual stent is adjusted in the interactive interface in response to the adjustment operation of the virtual stent implanted in the target blood vessel segment.

According to another aspect of the present application, an electronic device is provided, the electronic device comprising:

at least one processor;

and a memory communicatively coupled to the at least one processor;

The memory stores a computer program executable by the at least one processor, and the computer program is executed by the at least one processor so that the at least one processor can execute the virtual stent FFR calculation method described in any embodiment of the present application.

According to another aspect of the present application, a computer-readable storage medium is provided, wherein the computer-readable storage medium stores computer instructions, and the computer instructions are used to enable a processor to implement the virtual stent FFR calculation method described in any embodiment of the present application when executed.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG1 is a flow chart of a virtual stent FFR calculation method provided according to Embodiment 1 of the present application;

FIG2 is a flow chart of a virtual stent FFR calculation method provided according to Embodiment 2 of the present application;

FIG3 is a schematic diagram of a blood vessel contour of a target blood vessel segment provided according to Embodiment 2 of the present application;

FIG4 is a flow chart of a virtual stent FFR calculation method provided according to Embodiment 3 of the present application;

FIG5 is a flow chart of a virtual stent FFR calculation method provided according to Embodiment 4 of the present application;

FIG6 is an interface diagram of a first display area provided according to an embodiment of the present application;

FIG7 is an interface diagram of a second display area provided according to an embodiment of the present application;

FIG8 is a flow chart of a virtual stent FFR calculation method provided according to Embodiment 5 of the present application;

FIG9 is a flow chart of a virtual stent FFR calculation method provided according to Embodiment 6 of the present application;

FIG10 is a flow chart of a virtual stent FFR calculation method provided according to Embodiment 7 of the present application;

FIG11 is a flow chart of a virtual stent FFR calculation method provided according to Embodiment 8 of the present application;

12 is a schematic diagram of the structure of a virtual stent FFR calculation device provided according to Embodiment 9 of the present application;

FIG. 13 is a schematic diagram of the structure of an electronic device implementing an embodiment of the present application.

DETAILED DESCRIPTION

The technical solutions in the embodiments of the present application will be described below in conjunction with the drawings in the embodiments of the present application. The described embodiments are only part of the embodiments of the present application, rather than all the embodiments.

The terms "first", "second", etc. in the specification and claims of the present application and the above-mentioned drawings are used to distinguish similar objects, and are not necessarily used to describe a specific order or sequence. The data used in this way can be interchanged where appropriate, so that the embodiments of the present application described herein can be implemented in an order other than those illustrated or described herein. In addition, the terms "including" and "having" and any of their variations are intended to cover non-exclusive inclusions, for example, a process, method, system, product or device comprising a series of steps or units is not necessarily limited to those steps or units listed, but may include other steps or units that are not listed or inherent to these processes, methods, products or devices.

Embodiment 1

FIG1 is a flow chart of a virtual support FFR calculation method provided in the first embodiment of the present application. The present embodiment is applicable to the case where the FFR is automatically updated and displayed during the virtual support adjustment process. The method can be executed by a virtual support FFR calculation device, which can be implemented in the form of hardware and/or software, and can be configured in a terminal and/or a server. As shown in FIG1, the method includes the following steps.

S110 . In response to a selection operation on a target blood vessel segment, displaying the selected target blood vessel segment in an interactive interface.

In this embodiment, the target vessel segment refers to a vessel segment of interest selected from a coronary angiography image, for example, the target vessel segment may be a partial vessel segment of the left anterior descending artery, the left main coronary artery, the left circumflex artery, or the right coronary artery. The interactive interface refers to a software interface for managing and displaying medical data, and the interactive interface may be used to manage and display medical data such as coronary angiography images, target vessel segments, FFR, virtual stents, and stenotic lesion segments.

For example, a user can select a target blood vessel segment in the coronary angiography image on the interactive interface through an input device such as a keyboard, mouse, or touch screen. The terminal device responds to the user's selection operation of the target blood vessel segment and highlights the selected blood vessel segment in the interactive interface for the user to view and analyze.

S120 . In response to the adjustment operation on the virtual stent implanted in the target blood vessel segment, display the FFR of the virtual stent after adjustment in the interactive interface.

In this embodiment, after selecting the target blood vessel segment, a virtual stent can be implanted in the target blood vessel segment, and then the virtual stent implanted in the target blood vessel segment can be adjusted to achieve the best stent implantation effect and repair the stenotic lesion segment. Optionally, the adjustment operation of the virtual stent implanted in the target blood vessel segment includes one or more of the following operations: an operation of adjusting the position of the virtual stent implanted in the target blood vessel segment; The length adjustment operation of the virtual stent implanted in the target blood vessel segment; the specification adjustment operation of the virtual stent implanted in the target blood vessel segment; and the diameter adjustment operation of the virtual stent implanted in the target blood vessel segment. The specification of the virtual stent refers to the number, shape or type of the stent.

A virtual stent refers to a stent that is simulated and added to the lumen model. By implanting the virtual stent in the blood vessel lumen, the position, length, diameter or specification of the virtual stent is dynamically adjusted, and the adjusted FFR is displayed in real time to judge the repair effect of the stent implantation, providing a reference for actual stent implantation.

The technical solution of the embodiment of the present application, by responding to the user's adjustment operation on the virtual stent implanted in the target blood vessel segment, displays the FFR of the virtual stent in the target blood vessel segment in real time in the interactive interface, thereby solving the problem that the FFR of the virtual stent cannot be displayed in real time in the FFR determination system, and improving the timeliness of FFR.

Embodiment 2

FIG2 is a flow chart of a virtual stent FFR calculation method provided in the second embodiment of the present application. The method of this embodiment can be combined with multiple optional schemes in the virtual stent FFR calculation method provided in the above embodiments. This embodiment illustrates the virtual stent FFR calculation method provided. Optionally, in response to the selection operation of the target blood vessel segment, the selected target blood vessel segment is displayed in the interactive interface, including: in response to the selection operation of the first endpoint of the target blood vessel segment and the selection operation of the second endpoint of the target blood vessel segment, the first endpoint position information of the target blood vessel segment and the second endpoint position information of the target blood vessel segment are obtained; based on the first endpoint position information of the target blood vessel segment and the second endpoint position information of the target blood vessel segment, the angiography image to be processed is segmented to obtain the blood vessel contour of the target blood vessel segment; based on the blood vessel contour of the target blood vessel segment, the selected target blood vessel segment is highlighted in the interactive interface.

As shown in FIG. 2 , the method includes the following steps.

S210 . In response to the selection operation of the first endpoint of the target blood vessel segment and the selection operation of the second endpoint of the target blood vessel segment, obtain the first endpoint position information of the target blood vessel segment and the second endpoint position information of the target blood vessel segment.

In this embodiment, the first endpoint of the target blood vessel segment and the second endpoint of the target blood vessel segment are endpoints at both ends of the target blood vessel segment. The target blood vessel segment can be determined by selecting the starting point and the end point of the target blood vessel segment in the coronary angiography image.

S220 , segmenting the angiography image to be processed based on the first endpoint position information and the second endpoint position information of the target blood vessel segment to obtain a blood vessel contour of the target blood vessel segment.

In this embodiment, the first endpoint position information of the target blood vessel segment and the second endpoint position information of the target blood vessel segment are the endpoint coordinates of both ends of the target blood vessel segment respectively.

For example, the blood vessel contour can be obtained by a blood vessel segmentation method. The blood vessel segmentation method can be The image intensity-based threshold segmentation method, the deep learning model segmentation method, etc. are not limited here. For example, the vascular contour can be intercepted or selected according to the first endpoint position information of the target vascular segment and the second endpoint position information of the target vascular segment to obtain the vascular contour of the target vascular segment.

S230 : Based on the blood vessel contour of the target blood vessel segment, highlight the selected target blood vessel segment in the interactive interface.

The highlighting method may include changing one or more of the following: contour line segment color, contour line segment shape, contour line segment thickness, etc.

For example, Fig. 3 is a schematic diagram of a blood vessel contour of a target blood vessel segment provided in an embodiment of the present application, wherein point P is the selected starting point and point D is the selected end point. It can be seen from Fig. 3 that the selected target blood vessel segment is more prominent than other blood vessels for easier viewing by the user.

S240 . In response to the adjustment operation of the virtual stent implanted in the target blood vessel segment, display the FFR of the virtual stent after adjustment in the interactive interface.

The technical solution of the embodiment of the present application obtains the first endpoint position information and the second endpoint position information of the target blood vessel segment in response to the selection operation of the first endpoint of the target blood vessel segment and the selection operation of the second endpoint of the target blood vessel segment, and then performs segmentation processing on the processed angiography image according to the first endpoint position information and the second endpoint position information of the target blood vessel segment to obtain the blood vessel contour of the target blood vessel segment, and then highlights the selected target blood vessel segment in the interactive interface based on the blood vessel contour of the target blood vessel segment so that the user can view and analyze the target blood vessel segment.

Embodiment 3

FIG4 is a flow chart of a virtual stent FFR calculation method provided in Example 3 of the present application. The method of this embodiment can be combined with multiple optional schemes in the virtual stent FFR calculation method provided in the above embodiments. This embodiment illustrates the provided virtual stent FFR calculation method. Optionally, in response to the adjustment operation of the virtual stent implanted in the target blood vessel segment, the FFR of the virtual stent after adjustment is displayed in the interactive interface, including: in response to the adjustment operation of the virtual stent implanted in the target blood vessel segment, the FFR of the target blood vessel segment after the virtual stent is adjusted is determined; in the interactive interface, the FFR of the target blood vessel segment after the virtual stent is adjusted is displayed.

As shown in FIG4 , the method includes the following steps.

S310 . In response to a selection operation on a target blood vessel segment, displaying the selected target blood vessel segment in an interactive interface.

S320: In response to the adjustment operation of the virtual stent implanted in the target blood vessel segment, determine the FFR of the target blood vessel segment after the virtual stent is adjusted.

S330 , displaying the FFR of the target blood vessel segment after the virtual stent is adjusted in the interactive interface.

In this embodiment, the FFR of the target blood vessel segment may include the FFR of the main branch and the FFR of the side branch.

Exemplarily, determining the FFR of the target blood vessel segment after the virtual stent adjustment includes: determining the FFR of the main branch of the target blood vessel segment after the virtual stent adjustment; and/or determining the FFR of the side branch of the target blood vessel segment after the virtual stent adjustment.

Optionally, determining the FFR of the main branch of the target blood vessel segment after adjustment of the virtual stent includes: determining a first FFR corresponding to the first endpoint position of the virtual stent; determining a second FFR corresponding to the second endpoint position of the virtual stent; determining an FFR change value of the virtual stent segment after implantation of the virtual stent based on the first FFR and the second FFR; determining the FFR of the main branch of the target blood vessel segment after adjustment of the virtual stent based on the FFR of the main branch before implantation of the virtual stent and the FFR change value of the virtual stent segment after implantation of the virtual stent.

Exemplarily, the first FFR can be calculated based on the vascular flow or vascular pressure at the first endpoint, or it can be obtained from a preset storage path or other device, without any limitation here. The second FFR can be calculated based on the vascular flow or vascular pressure at the second endpoint, or it can be obtained from a preset storage path or other device, without any limitation here. Exemplarily, the first FFR can be subtracted from the second FFR to obtain the FFR change value of the virtual stent segment after the virtual stent is implanted, and then the FFR of the main branch before the virtual stent is implanted and the FFR change value of the virtual stent segment after the virtual stent is implanted can be added to obtain the FFR of the main branch of the target vascular segment after the virtual stent is adjusted.

Optionally, determining the FFR of the side branch of the target blood vessel segment after adjustment with the virtual stent includes: determining a third FFR corresponding to the proximal position of the blood vessel; determining a fourth FFR corresponding to the position of the side branch opening; determining a change in FFR from the proximal end of the blood vessel to the side branch opening after implantation of the virtual stent based on the third FFR and the fourth FFR; determining the FFR of the side branch of the target blood vessel segment after adjustment with the virtual stent based on the FFR of the side branch before implantation of the virtual stent and the change in FFR from the proximal end of the blood vessel to the side branch opening after implantation of the virtual stent.

Exemplarily, the third FFR can be calculated based on the vascular flow or vascular pressure at the proximal position of the blood vessel, or it can be obtained from a preset storage path or other device, without any limitation here. The fourth FFR can be calculated based on the vascular flow or vascular pressure at the side branch opening position, or it can be obtained from a preset storage path or other device, without any limitation here. Exemplarily, the third FFR can be subtracted from the fourth FFR to obtain the FFR change value of the segment from the proximal end of the blood vessel to the side branch opening after the virtual stent is implanted. Then, the side branch FFR before the virtual stent is implanted and the FFR change value of the segment from the proximal end of the blood vessel to the side branch opening after the virtual stent is implanted are added to obtain the FFR of the side branch of the target blood vessel segment after the virtual stent is adjusted.

The technical solution of the embodiment of the present application achieves precise determination of the FFR of the main branch and the side branch of the target vascular segment after adjustment of the virtual stent, thereby providing a precise and rich reference basis for the adjustment of the virtual stent.

Embodiment 4

FIG5 is a flowchart of a virtual stent FFR calculation method provided in Embodiment 4 of the present application. The method of this embodiment can be combined with multiple optional schemes in the virtual stent FFR calculation method provided in the above embodiments. This embodiment describes the virtual stent FFR calculation method provided. Optionally, after the adjustment operation of the virtual stent implanted in the target blood vessel segment in response to the adjustment operation, the method includes: displaying the adjusted virtual stent in the interactive interface.

As shown in FIG5 , the method includes the following steps.

S410 . In response to a selection operation on a target blood vessel segment, displaying the selected target blood vessel segment in an interactive interface.

S420: In response to the adjustment operation of the virtual stent implanted in the target blood vessel segment, the FFR of the virtual stent after adjustment is displayed in the interactive interface, and the adjusted virtual stent is displayed in the interactive interface.

In this embodiment, after the virtual stent is adjusted, the adjusted virtual stent may be displayed at the target section of the target blood vessel section of the interactive interface, so that the user can quickly know the position and status of the adjusted virtual stent.

Optionally, the adjusted virtual stent is displayed in the interactive interface, including: displaying the adjusted virtual stent in the form of a grid at the target segment of the first display area of the interactive interface; and/or displaying the adjusted virtual stent in the form of a target fill color at the target segment of the second display area of the interactive interface; wherein the target segment of the first display area and the target segment of the second display area are the same virtual stent implantation position on the target blood vessel segment.

The target segment refers to a segment in the display area or a preset range area, for example, the target segment may be an area near a stenotic lesion segment in a target blood vessel segment.

Exemplarily, FIG6 is an interface diagram of the first display area provided in an embodiment of the present application, in which the adjusted virtual stent is displayed in a grid above the stenotic lesion segment in the first display area, and the length of the virtual stent is greater than the length of the stenotic lesion segment. FIG7 is an interface diagram of the second display area provided in an embodiment of the present application, in which the adjusted virtual stent is displayed in a gray-white filled form in the target blood vessel segment of the second display area to highlight the position of the virtual stent in the target blood vessel.

The adjusted virtual bracket can be synchronously displayed in the first display area and the second display area of the interactive interface, that is, when the virtual bracket is adjusted, the virtual bracket in the first display area and the virtual bracket in the second display area will move or change synchronously to achieve the effect of screen linkage, so that users can view and analyze.

In this embodiment, the Vessel Quantitative Flow Ratio (QFR) in FIG. 7 represents the FFR before the virtual stent is implanted, and its value is 0.82; ΔQFR represents the FFR change value, and its value is 0.15; Residual QFR represents the FFR after the virtual stent is adjusted, and its value is 0.97. 29.2 represents the length of the virtual stent, and 3.6/2.7 represent the diameters of the two ends of the virtual stent, respectively. B1 to B5 represent 5 branches, respectively.

The technical solution of the embodiment of the present application enables the user to quickly know the position of the adjusted virtual bracket by displaying the adjusted virtual bracket in the interactive interface.

Embodiment 5

FIG8 is a flow chart of a virtual stent FFR calculation method provided in Example 5 of the present application. The method of this embodiment can be combined with multiple optional schemes in the virtual stent FFR calculation method provided in the above embodiments. This embodiment describes the virtual stent FFR calculation method provided. Optionally, the method also includes: in the interactive interface, differentially displaying the FFR at each position of the target blood vessel segment before the virtual stent is implanted.

As shown in FIG8 , the method includes the following steps.

S510 . In the interactive interface, differentially display the FFR at each position of the target blood vessel segment before the virtual stent is implanted.

Among them, the difference display method may include color difference display, line thickness difference display, shape difference display, etc., and no limitation is made here.

Optionally, in the interactive interface, the FFR at each position of the target blood vessel segment before the virtual stent is implanted is displayed differentially, including: in the interactive interface, the FFR at each position of the target blood vessel segment before the virtual stent is implanted is displayed differentially in the form of color gradient line segments, wherein different colors correspond to different FFR interval segments.

For example, the vertical axis on the right side of FIG. 6 represents the FFR value. The color cannot be displayed in FIG. 6, so it is represented by letters here. The color gradient line segment A is the FFR change curve at each position of the target blood vessel segment before the virtual stent is implanted, which is used to show the change trend of FFR, wherein the FFR change interval can be (0.6, 1), and different color line segments correspond to different FFR interval segments. The color cannot be displayed in FIG. 6, so it is represented by letters here. For example, the FFR corresponding to the yellow line segment area B is 0.8, and the FFR corresponding to the blue line segment area C is 1.

S520 . In response to the selection operation of the target blood vessel segment, display the selected target blood vessel segment in the interactive interface.

S530: In response to the adjustment operation of the virtual stent implanted in the target blood vessel segment, display the FFR of the virtual stent after adjustment in the interactive interface.

The technical solution of the embodiment of the present application allows the user to quickly know the FFR at each position of the target blood vessel segment and the change trend of FFR by differentially displaying the FFR at each position of the target blood vessel segment before virtual stent implantation in the interactive interface.

Embodiment 6

FIG9 is a flow chart of a virtual stent FFR calculation method provided in Example 6 of the present application. The method of this embodiment can be combined with multiple optional schemes in the virtual stent FFR calculation method provided in the above embodiments. This embodiment describes the virtual stent FFR calculation method provided. Optionally, after responding to the selection operation of the target blood vessel segment, the method also includes: determining the blood flow velocity of the target blood vessel segment, and displaying the blood flow velocity of the target blood vessel segment in the interactive interface.

As shown in FIG. 9 , the method includes the following steps.

S610. In response to a selection operation on a target blood vessel segment, display the selected target blood vessel segment in an interactive interface; determine the blood flow velocity of the target blood vessel segment, and display the blood flow velocity of the target blood vessel segment in the interactive interface.

By displaying the blood flow velocity of the target blood vessel segment in the interactive interface, the user is informed of the blood flow velocity of the current target blood vessel segment, so that the user can view and analyze it.

Optionally, determining the blood flow velocity of the target blood vessel segment includes: determining the length of the blood vessel through which the contrast agent flows based on multiple frames of angiography images to be processed; and determining the blood flow velocity of the target blood vessel segment based on the length of the blood vessel through which the contrast agent flows and the time corresponding to the length of the blood vessel through which the contrast agent flows.

Exemplarily, the calculation formula of the blood flow velocity of the target blood vessel segment is calculated as follows:
V = S/T;

Wherein, V represents the blood flow velocity of the target blood vessel segment, S represents the length of the blood vessel through which the contrast agent flows, and T represents the time taken to flow through the current blood vessel length.

S620: In response to the adjustment operation of the virtual stent implanted in the target blood vessel segment, display the FFR of the virtual stent after adjustment in the interactive interface.

The technical solution of the embodiment of the present application, by responding to the user's adjustment operation on the virtual stent implanted in the target blood vessel segment, displays the blood flow velocity of the target blood vessel segment in real time in the interactive interface, thereby solving the problem that in the FFR determination system, the blood flow velocity of the target blood vessel segment after the virtual stent is adjusted cannot be displayed in real time, and improves the timeliness of the blood flow velocity.

Embodiment 7

FIG10 is a flowchart of a virtual stent FFR calculation method provided in Embodiment 7 of the present application. The method of this embodiment can be combined with multiple optional schemes in the virtual stent FFR calculation method provided in the above embodiments. This embodiment describes the virtual stent FFR calculation method provided. The method further includes: in response to an adjustment operation on the target viewing position in the target blood vessel segment, displaying reference information of the target viewing position of the target blood vessel segment after the adjustment operation in an interactive interface; wherein the reference information of the target viewing position includes one or more of FFR, lumen diameter, diameter stenosis rate and area stenosis rate.

As shown in FIG. 10 , the method includes the following steps.

S710 . In response to a selection operation on a target blood vessel segment, displaying the selected target blood vessel segment in an interactive interface.

S720: In response to the adjustment operation of the virtual stent implanted in the target blood vessel segment, display the FFR of the virtual stent after adjustment in the interactive interface.

S730. In response to an adjustment operation on a target viewing position in a target blood vessel segment, reference information of the target viewing position of the target blood vessel segment after the adjustment operation is displayed in an interactive interface; wherein the reference information of the target viewing position includes one or more of FFR, lumen diameter, diameter stenosis rate, and area stenosis rate.

The target viewing position is any position in the target blood vessel segment selected by the user. The user can realize the positioning viewing of the reference information of the blood vessel position that the user is interested in by adjusting the target viewing position.

Exemplarily, the vertical line in FIG6 is a reference line of the target viewing position, 50% represents the diameter stenosis rate of the target viewing position, 75% represents the area stenosis rate of the target viewing position, 1.4 mm represents the lumen diameter of the target viewing position, and 0.95 represents the FFR of the target viewing position.

Optionally, after responding to an adjustment operation on the target viewing position in the target vascular segment, the method further includes: displaying a reference line of the target viewing position after the adjustment operation at the target viewing position in a first display area of the interactive interface; and/or displaying a reference line of the target viewing position after the adjustment operation at the target viewing position in a second display area of the interactive interface; wherein the target viewing position in the first display area and the target viewing position in the second display area are the same viewing position on the target vascular segment.

The reference line of the target viewing position in the first display area and the reference line of the target viewing position in the second display area can be displayed synchronously, that is, when the user moves the reference line of the target viewing position in any display area, the reference line of the target viewing position in the other display area moves accordingly, achieving a screen linkage effect.

Optionally, the method further includes: displaying the proximal opening mark and the distal opening mark of the reference lumen in the interactive interface. For example, in FIG6 , PN represents the proximal opening mark of the reference lumen, and DN represents the distal opening mark of the reference lumen. By displaying the proximal opening mark and the distal opening mark of the reference lumen in the interactive interface, the user can know the position of the proximal opening and the distal opening of the current reference lumen. settings to facilitate user analysis and adjustment.

Optionally, the method further includes: establishing a reference lumen model in response to an adjustment operation on the proximal opening marker and/or the distal opening marker.

By adjusting the proximal opening mark and/or the distal opening mark, the blood vessel geometric parameters can be changed, thereby changing the reference lumen model. In other words, by adjusting the proximal opening mark and/or the distal opening mark, the reference lumen model can be updated for analysis and viewing by the user.

The technical solution of the embodiment of the present application enables the user to adjust the target viewing position to realize the positioning viewing of the reference information of the blood vessel position that the user is interested in, making the viewing more targeted.

Embodiment 8

FIG11 is a flow chart of a virtual stent FFR calculation method provided in Example 8 of the present application. The method of this embodiment can be combined with multiple optional schemes in the virtual stent FFR calculation method provided in the above embodiments. This embodiment illustrates the provided virtual stent FFR calculation method. Optionally, the method further includes one or more of the following contents: displaying cross-sectional information of the actual lumen model in the interactive interface; displaying cross-sectional information of the reference lumen model in the interactive interface; displaying the stenosis lesion segment in the interactive interface, wherein the actual lumen model and the reference lumen model are displayed in an overlay manner.

As shown in FIG. 11 , the method includes the following steps.

S810: In response to a selection operation on a target blood vessel segment, displaying the selected target blood vessel segment in an interactive interface.

S820: In response to the adjustment operation of the virtual stent implanted in the target blood vessel segment, display the FFR of the virtual stent after adjustment in the interactive interface.

S830, displaying cross-sectional information of the actual lumen model in the interactive interface; displaying cross-sectional information of the reference lumen model in the interactive interface; and/or, displaying a stenotic lesion segment in the interactive interface.

In this embodiment, a lumen model can be established based on the contour information of the main branch and the side branch of the blood vessel, and the cross-sectional information of the actual lumen model can be the transverse cross-sectional or longitudinal cross-sectional information of the actual lumen, which is not limited here. An ideal lumen model can be established based on the actual lumen model, and the cross-sectional information of the reference lumen model can be the transverse cross-sectional or longitudinal cross-sectional information of the reference lumen, which is not limited here. A stenotic lesion segment refers to a part where a vascular lesion occurs and the shape becomes narrow.

Optionally, displaying the cross-sectional information of the actual lumen model in the interactive interface includes: filling and displaying the interior of the cross-sectional area of the actual lumen model with a first preset color in the interactive interface.

The first preset color may be a color pre-configured by the user, which is not limited here. For example, the gray filled area in FIG6 is the actual lumen of the target blood vessel segment. The cross-sectional area of the model can be used to understand the changing trend of the actual lumen diameter.

Optionally, displaying the cross-sectional information of the reference lumen model in the interactive interface includes: differentially displaying the cross-sectional area contour of the reference lumen model in a second preset color in the interactive interface.

Among them, the second preset color can be a color pre-configured by the user, and the color is not limited here. Exemplarily, the line segment area surrounding the gray filled area or intersecting the gray filled area in Figure 6 is the reference lumen of the target blood vessel segment. By viewing the cross-sectional area of the reference lumen model, the change trend of the reference lumen diameter can be known; when the actual lumen model and the reference lumen model are superimposed, the actual lumen model can be compared with the reference lumen model, so that the vascular stenosis lesion can be known.

Optionally, displaying the stenotic lesion segment in the interactive interface includes: differentially displaying the stenotic lesion segment in a third preset color in the interactive interface, wherein the length of the stenotic lesion segment is less than the length of the virtual stent.

The third preset color may be a color pre-configured by the user, and the color is not limited here. Exemplarily, the solid filled area in the grid area corresponding to the virtual stent in FIG6 is a stenotic lesion segment, wherein the length of the stenotic lesion segment is less than the length of the virtual stent, so that the stent covers the stenotic lesion segment.

The technical solution of the embodiment of the present application provides a reference basis for stent adjustment by displaying one or more of the cross-sectional information of the actual lumen model, the cross-sectional information of the reference lumen model, and the stenosis lesion segment in the interactive interface.

Embodiment 9

FIG12 is a schematic diagram of the structure of a virtual stent FFR calculation device provided in Embodiment 9 of the present application. As shown in FIG12 , the device includes: a target blood vessel segment selection module 910 and an FFR display module 920 .

A target blood vessel segment selection module 910 is configured to display the selected target blood vessel segment in an interactive interface in response to a selection operation on the target blood vessel segment;

The FFR display module 920 is configured to display the FFR after the virtual stent is adjusted in the interactive interface in response to the adjustment operation of the virtual stent implanted in the target blood vessel segment.

The technical solution of the embodiment of the present application, by responding to the user's adjustment operation on the virtual stent implanted in the target blood vessel segment, displays the FFR of the virtual stent in the target blood vessel segment in real time in the interactive interface, thereby solving the problem that the FFR of the virtual stent cannot be displayed in real time in the FFR determination system, and improving the timeliness of FFR.

In some optional implementations, the target blood vessel segment selection module 910 may also be configured as follows:

In response to the selection operation of the first endpoint of the target blood vessel segment and the selection operation of the second endpoint of the target blood vessel segment, obtaining the first endpoint position information of the target blood vessel segment and the second endpoint position information of the target blood vessel segment;

Segmenting the angiography image to be processed based on the first endpoint position information of the target blood vessel segment and the second endpoint position information of the target blood vessel segment to obtain a blood vessel contour of the target blood vessel segment;

Based on the blood vessel contour of the target blood vessel segment, the selected target blood vessel segment is highlighted in the interactive interface.

In some optional embodiments, the FFR display module 920 includes:

An FFR determination unit is configured to determine the FFR of the target blood vessel segment after the virtual stent is adjusted in response to an adjustment operation of the virtual stent implanted in the target blood vessel segment;

The FFR display unit is configured to display the FFR of the target blood vessel segment after the virtual stent is adjusted in the interactive interface.

In some optional embodiments, the FFR display unit comprises:

a main branch FFR determination subunit, configured to determine the FFR of the main branch of the target blood vessel segment after the virtual stent is adjusted;

And/or, a side branch FFR determination subunit is configured to determine the FFR of a side branch of the target blood vessel segment after the virtual stent is adjusted.

In some optional implementations, the main branch FFR determination subunit may also be set to:

Determine a first FFR corresponding to a first endpoint position of the virtual stent;

Determine a second FFR corresponding to the second endpoint position of the virtual stent;

Determining an FFR change value of a virtual stent segment after virtual stent implantation based on the first FFR and the second FFR;

The FFR of the main branch of the target blood vessel segment after the virtual stent is adjusted is determined based on the FFR of the main branch before the virtual stent is implanted and the FFR change value of the virtual stent segment after the virtual stent is implanted.

In some optional implementations, the side branch FFR determination subunit may also be set to:

Determine the third FFR corresponding to the proximal position of the blood vessel;

Determine the fourth FFR corresponding to the side branch opening position;

Determine the FFR change value of the segment from the proximal end of the blood vessel to the side branch opening after the virtual stent is implanted based on the third FFR and the fourth FFR;

Based on the FFR of the side branch before virtual stent implantation and the vascular volume after the virtual stent implantation The FFR change value from the proximal end to the side branch opening segment determines the FFR of the side branch of the target blood vessel segment after the virtual stent is adjusted.

In some optional embodiments, the adjustment operation of the virtual stent implanted in the target blood vessel segment includes one or more of the following operations:

Adjusting the position of the virtual stent implanted in the target blood vessel segment;

Adjusting the length of the virtual stent implanted in the target blood vessel segment;

Adjusting the specifications of the virtual stent implanted in the target blood vessel segment;

The diameter of the virtual stent implanted in the target blood vessel segment is adjusted.

In some optional embodiments, the virtual stent FFR calculation device further includes:

The virtual support display module is configured to display the adjusted virtual support in the interactive interface.

In some optional implementations, the virtual support display module may also be configured as:

Displaying the adjusted virtual bracket in a grid format at a target section of a first display area of the interactive interface;

and/or, displaying the adjusted virtual bracket in a target section of the second display area of the interactive interface in the form of a target filling color;

The target section of the first display area and the target section of the second display area are the same virtual stent implantation position on the target blood vessel segment.

In some optional embodiments, the virtual stent FFR calculation device further includes:

The pre-implantation score display module is configured to differentially display the FFR at each position of the target blood vessel segment before the virtual stent is implanted in the interactive interface.

In some optional implementations, the pre-implantation score display module may also be configured as:

In the interactive interface, the FFR at each position of the target blood vessel segment before the virtual stent is implanted is displayed differently in the form of color gradient line segments, where different colors correspond to different FFR interval segments.

In some optional embodiments, the virtual stent FFR calculation device further includes:

The blood flow velocity display module is configured to determine the blood flow velocity of the target blood vessel segment and display the blood flow velocity of the target blood vessel segment in an interactive interface.

In some optional implementations, the blood flow velocity display module may also be configured as:

Determining the blood flow per unit time of the target blood vessel segment and the vascular lumen area of the target blood vessel segment;

The blood flow velocity of the target blood vessel segment is determined based on the blood flow per unit time of the target blood vessel segment and the blood vessel lumen area of the target blood vessel segment.

In some optional implementations, the blood flow velocity display module may also be configured as:

determining the length of the blood vessel through which the contrast agent flows according to a plurality of frames of angiography images to be processed;

The blood flow velocity of the target blood vessel segment is determined based on the blood vessel length through which the contrast agent flows and the time corresponding to the blood vessel length through which the contrast agent flows.

In some optional embodiments, the virtual stent FFR calculation device further includes:

The viewing position adjustment module is configured to respond to an adjustment operation on a target viewing position in a target blood vessel segment and display reference information of the target viewing position of the target blood vessel segment after the adjustment operation in an interactive interface; wherein the reference information of the target viewing position includes one or more of FFR, lumen diameter, diameter stenosis rate, and area stenosis rate.

In some optional implementations, the viewing position adjustment module may also be set to:

Displaying a reference line of the target viewing position after the adjustment operation at the target viewing position in the first display area of the interactive interface;

and/or, displaying a reference line of the target viewing position after the adjustment operation at the target viewing position in the second display area of the interactive interface;

The target viewing position of the first display area and the target viewing position of the second display area are the same viewing position on the target blood vessel segment.

In some optional embodiments, the virtual stent FFR calculation device further includes:

The opening mark display module is configured to display the proximal opening mark and the distal opening mark of the reference lumen in the interactive interface.

In some optional embodiments, the virtual stent FFR calculation device further includes:

The reference lumen model establishment module is configured to establish a reference lumen model in response to an adjustment operation on the proximal opening mark and/or the distal opening mark.

In some optional embodiments, the virtual stent FFR calculation device further includes one or more of the following:

An actual lumen model display module, configured to display cross-sectional information of the actual lumen model in an interactive interface;

A reference lumen model display module, configured to display cross-sectional information of the reference lumen model in an interactive interface;

A stenosis lesion segment display module, configured to display the stenosis lesion segment in an interactive interface;

The actual lumen model and the reference lumen model are displayed in a superimposed manner.

In some optional implementations, the actual lumen model display module may also be configured as:

In the interactive interface, the interior of the cross-sectional area of the actual lumen model is filled and displayed with a first preset color.

In some optional implementations, the reference lumen model display module may also be configured as follows:

In the interactive interface, the cross-sectional area contour of the reference lumen model is differentially displayed with a second preset color.

In some optional implementations, the stenosis lesion segment display module may also be configured as:

In the interactive interface, the stenotic lesion segment is differentially displayed in a third preset color, wherein the length of the stenotic lesion segment is smaller than the length of the virtual stent.

The virtual stent FFR calculation device provided in the embodiment of the present application can execute the virtual stent FFR calculation method provided in any embodiment of the present application, and has the corresponding functional modules and effects of the execution method.

Embodiment 10

FIG13 shows a block diagram of an electronic device 10 that can be used to implement an embodiment of the present application. The electronic device is intended to represent various forms of digital computers, such as laptop computers, desktop computers, workbenches, personal digital assistants, servers, blade servers, mainframe computers, and other suitable computers. The electronic device can also represent various forms of mobile devices, such as personal digital assistants, cellular phones, smart phones, wearable devices (such as helmets, glasses, watches, etc.) and other similar computing devices. The components shown herein, their connections and relationships, and their functions are merely examples and are not intended to limit the implementation of the present application described and/or required herein.

As shown in FIG. 13 , the electronic device 10 includes at least one processor 11, and a memory connected to the at least one processor 11, such as a read-only memory (ROM) 12, a random access memory (RAM) 13, etc., wherein the memory stores a computer program that can be executed by at least one processor 11, and the processor 11 can perform a variety of appropriate actions and processes according to the computer program stored in the ROM 12 or the computer program loaded from the storage unit 18 to the RAM 13. In the RAM 13, a variety of programs and data required for the operation of the electronic device 10 can also be stored. The processor 11, the ROM 12, and the RAM 13 are connected to each other through a bus 14. An input/output (I/O) interface 15 is also connected to the bus 14.

A number of components in the electronic device 10 are connected to the I/O interface 15, including: an input unit 16, such as a keyboard, a mouse, etc.; an output unit 17, such as various types of displays, speakers, etc.; a storage unit 18, such as a disk, an optical disk, etc.; and a communication unit 19, such as a network card, a modem, a wireless communication transceiver, etc. The communication unit 19 allows the electronic device 10 to communicate with a computer network such as the Internet. and/or various telecommunication networks to exchange information/data with other devices.

The processor 11 may be a variety of general and/or special processing components with processing and computing capabilities. Some examples of the processor 11 include a central processing unit (CPU), a graphics processing unit (GPU), a variety of special artificial intelligence (AI) computing chips, a variety of processors running machine learning model algorithms, a digital signal processor (DSP), and any appropriate processor, controller, microcontroller, etc. The processor 11 performs the multiple methods and processes described above, such as a virtual stent FFR calculation method, which includes:

In response to a selection operation on a target blood vessel segment, displaying the selected target blood vessel segment in an interactive interface;

In response to the adjustment operation of the virtual stent implanted in the target blood vessel segment, the FFR of the virtual stent after adjustment is displayed in the interactive interface.

In some embodiments, the virtual stent FFR calculation method may be implemented as a computer program, which is tangibly contained in a computer-readable storage medium, such as a storage unit 18. In some embodiments, part or all of the computer program may be loaded and/or installed on the electronic device 10 via the ROM 12 and/or the communication unit 19. When the computer program is loaded into the RAM 13 and executed by the processor 11, one or more steps of the virtual stent FFR calculation method described above may be performed. Alternatively, in other embodiments, the processor 11 may be configured to perform the virtual stent FFR calculation method in any other appropriate manner (e.g., by means of firmware).

Various embodiments of the systems and techniques described above herein may be implemented in digital electronic circuit systems, integrated circuit systems, field programmable gate arrays (FPGAs), application specific integrated circuits (ASICs), application specific standard parts (ASSPs), system on chip systems (SOCs), complex programmable logic devices (CPLDs), computer hardware, firmware, software, and/or combinations thereof. These various embodiments may include: being implemented in one or more computer programs that are executable and/or interpreted on a programmable system including at least one programmable processor that may be a special purpose or general purpose programmable processor that may receive data and instructions from a storage system, at least one input device, and at least one output device, and transmit data and instructions to the storage system, the at least one input device, and the at least one output device.

The computer programs for implementing the methods of the present application may be written in any combination of one or more programming languages. These computer programs may be provided to a processor of a general-purpose computer, a special-purpose computer or other programmable data processing device, so that when the computer program is executed by the processor, the functions/operations specified in the flowchart and/or block diagram are implemented. The computer program may be executed entirely on the machine, Partially on the machine, partly on the machine as a stand-alone software package and partly on a remote machine, or entirely on a remote machine or server.

In the context of the present application, a computer readable storage medium may be a tangible medium that may contain or store a computer program for use by or in conjunction with an instruction execution system, device, or apparatus. A computer readable storage medium may include an electronic, magnetic, optical, electromagnetic, infrared, or semiconductor system, device, or device, or any suitable combination of the foregoing. Alternatively, a computer readable storage medium may be a machine readable signal medium. A machine readable storage medium includes an electrical connection based on one or more lines, a portable computer disk, a hard disk, a RAM, a ROM, an Erasable Programmable Read-Only Memory (EPROM), a flash memory, an optical fiber, a portable compact disk read-only memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the foregoing. The storage medium may be a non-transitory storage medium.

To provide interaction with a user, the systems and techniques described herein may be implemented on an electronic device having: a display device (e.g., a cathode ray tube (CRT) or a liquid crystal display (LCD) monitor) for displaying information to the user; and a keyboard and pointing device (e.g., a mouse or trackball) through which the user can provide input to the electronic device. Other types of devices may also be used to provide interaction with the user; for example, the feedback provided to the user may be any form of sensory feedback (e.g., visual feedback, auditory feedback, or tactile feedback); and input from the user may be received in any form (including acoustic input, voice input, or tactile input).

The systems and techniques described herein may be implemented in a computing system that includes backend components (e.g., as a data server), or a computing system that includes middleware components (e.g., an application server), or a computing system that includes frontend components (e.g., a user computer with a graphical user interface or a web browser through which a user can interact with implementations of the systems and techniques described herein), or a computing system that includes any combination of such backend components, middleware components, or frontend components. The components of the system may be interconnected by any form or medium of digital data communication (e.g., a communication network). Examples of communication networks include: Local Area Network (LAN), Wide Area Network (WAN), blockchain network, and the Internet.

A computing system may include clients and servers. Clients and servers are generally remote from each other and usually interact through a communication network. The client-server relationship is created by computer programs running on respective computers and having a client-server relationship with each other. The server may be a cloud server, also known as a cloud computing server or cloud host, which is a host product in the cloud computing service system to solve the problem of the difference between traditional physical hosts and virtual private servers (VPS). The service has the defects of high management difficulty and weak business scalability.

The various forms of processes shown above can be used to reorder, add or delete steps. For example, the multiple steps recorded in this application can be executed in parallel, sequentially or in different orders, as long as the expected results of the technical solution of this application can be achieved, and this document is not limited here.

Claims (24)

A virtual stent blood flow reserve fraction FFR calculation method, comprising: In response to a selection operation on a target blood vessel segment, displaying the selected target blood vessel segment in an interactive interface; In response to an adjustment operation on the virtual stent implanted in the target blood vessel segment, the FFR of the virtual stent after adjustment is displayed in the interactive interface. The method according to claim 1, wherein, in response to the selection operation of the target blood vessel segment, displaying the selected target blood vessel segment in the interactive interface comprises: In response to the selection operation of the first endpoint of the target blood vessel segment and the selection operation of the second endpoint of the target blood vessel segment, obtaining the first endpoint position information of the target blood vessel segment and the second endpoint position information of the target blood vessel segment; Segmenting the angiography image to be processed based on the first endpoint position information of the target blood vessel segment and the second endpoint position information of the target blood vessel segment to obtain a blood vessel contour of the target blood vessel segment; Based on the blood vessel contour of the target blood vessel segment, the selected target blood vessel segment is highlighted in the interactive interface. The method according to claim 1, wherein, in response to the adjustment operation of the virtual stent implanted in the target blood vessel segment, displaying the FFR adjusted by the virtual stent in the interactive interface comprises: In response to an adjustment operation of the virtual stent implanted in the target blood vessel segment, determining the FFR of the target blood vessel segment after the virtual stent is adjusted; In the interactive interface, the FFR of the target blood vessel segment after the virtual stent is adjusted is displayed. The method according to claim 3, wherein determining the FFR of the target blood vessel segment after the virtual stent is adjusted comprises at least one of the following: Determining the FFR of the main branch of the target blood vessel segment after the virtual stent is adjusted; Or, determine the FFR of the side branch of the target blood vessel segment after the virtual stent is adjusted. The method according to claim 4, wherein determining the FFR of the main branch of the target blood vessel segment after the virtual stent is adjusted comprises: Determine a first FFR corresponding to a first endpoint position of the virtual stent; Determine a second FFR corresponding to the second endpoint position of the virtual stent; Determining an FFR change value of the virtual stent segment after implantation of the virtual stent based on the first FFR and the second FFR; Based on the FFR of the main branch before the virtual stent is implanted and the FFR change value of the virtual stent segment after the virtual stent is implanted, the FFR of the main branch of the target blood vessel segment after the virtual stent is adjusted is determined. The method according to claim 4, wherein determining the FFR of the side branch of the target blood vessel segment after the virtual stent is adjusted comprises: Determine the third FFR corresponding to the proximal position of the blood vessel; Determine the fourth FFR corresponding to the side branch opening position; Determine the FFR change value of the segment from the proximal end of the blood vessel to the side branch opening after the virtual stent is implanted based on the third FFR and the fourth FFR; Based on the FFR of the side branch before implantation of the virtual stent and the FFR change value of the segment from the proximal end of the blood vessel to the opening of the side branch after implantation of the virtual stent, the FFR of the side branch of the target blood vessel segment after adjustment of the virtual stent is determined. The method according to claim 1, wherein the adjustment operation of the virtual stent implanted in the target blood vessel segment comprises at least one of the following operations: Adjusting the position of the virtual stent implanted in the target blood vessel segment; Adjusting the length of the virtual stent implanted in the target blood vessel segment; Adjusting the specifications of the virtual stent implanted in the target blood vessel segment; The diameter of the virtual stent implanted in the target blood vessel segment is adjusted. The method according to claim 1, wherein after the adjustment operation in response to the virtual stent implanted in the target blood vessel segment, the method further comprises: The adjusted virtual bracket is displayed in the interactive interface. The method according to claim 8, wherein displaying the adjusted virtual bracket in the interactive interface comprises at least one of the following: Displaying the adjusted virtual bracket in a grid format at a target section of the first display area of the interactive interface; Or, displaying the adjusted virtual bracket in a target section of the second display area of the interactive interface in the form of a target filling color; The target section of the first display area and the target section of the second display area are the same virtual stent implantation position on the target blood vessel segment. The method according to claim 1, further comprising: In the interactive interface, the FFR at each position of the target blood vessel segment before the virtual stent is implanted is displayed differently. The method according to claim 10, wherein the differential display of the FFR at each position of the target blood vessel segment before the virtual stent implantation in the interactive interface comprises: In the interactive interface, the FFR at each position of the target blood vessel segment before the virtual stent is implanted is displayed differently in the form of color gradient line segments, wherein different colors correspond to different FFR interval segments. The method according to claim 1, wherein after responding to the operation of selecting the target blood vessel segment, the method further comprises: The blood flow velocity of the target blood vessel segment is determined, and the blood flow velocity of the target blood vessel segment is displayed in the interactive interface. The method according to claim 12, wherein determining the blood flow velocity of the target blood vessel segment comprises: determining the length of the blood vessel through which the contrast agent flows according to a plurality of frames of angiography images to be processed; The blood flow velocity of the target blood vessel segment is determined based on the blood vessel length through which the contrast agent flows and the time corresponding to the blood vessel length through which the contrast agent flows. The method according to claim 1, further comprising: In response to an adjustment operation on a target viewing position in the target blood vessel segment, reference information of the target viewing position of the target blood vessel segment after the adjustment operation is displayed in the interactive interface; wherein the reference information of the target viewing position includes at least one of FFR, lumen diameter, diameter stenosis rate, and area stenosis rate. The method according to claim 14, wherein after the response to the adjustment operation of the target viewing position in the target blood vessel segment, the method further comprises at least one of the following: Displaying a reference line of the target viewing position after the adjustment operation at the target viewing position in the first display area of the interactive interface; or, displaying a reference line of the target viewing position after the adjustment operation at the target viewing position in the second display area of the interactive interface; The target viewing position of the first display area and the target viewing position of the second display area are the same viewing position on the target blood vessel segment. The method according to claim 1, further comprising: The proximal opening mark and the distal opening mark of the reference lumen are displayed in the interactive interface. The method according to claim 16, further comprising: In response to an adjustment operation on at least one of the proximal opening mark or the distal opening mark, a reference lumen model is established. The method according to claim 1, further comprising at least one of the following: Displaying cross-sectional information of the actual lumen model in the interactive interface; Displaying cross-sectional information of the reference lumen model in the interactive interface; Displaying the stenotic lesion segment in the interactive interface; The actual lumen model and the reference lumen model are displayed in a superimposed manner. The method according to claim 18, wherein displaying cross-sectional information of the actual lumen model in the interactive interface comprises: In the interactive interface, the interior of the cross-sectional area of the actual lumen model is filled and displayed with a first preset color. The method according to claim 18, wherein displaying cross-sectional information of the reference lumen model in the interactive interface comprises: In the interactive interface, the cross-sectional area contour of the reference lumen model is differentially displayed in a second preset color. The method according to claim 18, wherein displaying the stenotic lesion segment in the interactive interface comprises: In the interactive interface, the stenotic lesion segment is differentially displayed in a third preset color, wherein the length of the stenotic lesion segment is smaller than the length of the virtual stent. A virtual stent blood flow reserve fraction FFR calculation device, comprising: a target blood vessel segment selection module, configured to display the selected target blood vessel segment in an interactive interface in response to a selection operation on the target blood vessel segment; The FFR display module is configured to display the FFR after the virtual stent is adjusted in the interactive interface in response to the adjustment operation of the virtual stent implanted in the target blood vessel segment. An electronic device, comprising: at least one processor; and a memory communicatively coupled to the at least one processor; The memory stores a computer program executable by the at least one processor, and the computer program is executed by the at least one processor so that the at least one processor can execute The method for calculating the virtual stent fractional flow reserve (FFR) according to any one of claims 1 to 21. A computer-readable storage medium, wherein the computer-readable storage medium stores computer instructions, and the computer instructions are used to enable a processor to implement the virtual stent blood flow reserve fraction FFR calculation method according to any one of claims 1 to 21 when executed.