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WO2025038446A3 - Use of remimazolam for pediatric sedation - Google Patents

Use of remimazolam for pediatric sedation Download PDF

Info

Publication number
WO2025038446A3
WO2025038446A3 PCT/US2024/041709 US2024041709W WO2025038446A3 WO 2025038446 A3 WO2025038446 A3 WO 2025038446A3 US 2024041709 W US2024041709 W US 2024041709W WO 2025038446 A3 WO2025038446 A3 WO 2025038446A3
Authority
WO
WIPO (PCT)
Prior art keywords
remimazolam
pediatric
sedation
pediatric sedation
subject
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/US2024/041709
Other languages
French (fr)
Other versions
WO2025038446A2 (en
Inventor
Lynn BICHAJIAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eagle Pharmaceuticals Inc
Original Assignee
Eagle Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eagle Pharmaceuticals Inc filed Critical Eagle Pharmaceuticals Inc
Publication of WO2025038446A2 publication Critical patent/WO2025038446A2/en
Publication of WO2025038446A3 publication Critical patent/WO2025038446A3/en
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A61K31/5517—1,4-Benzodiazepines, e.g. diazepam or clozapine condensed with five-membered rings having nitrogen as a ring hetero atom, e.g. imidazobenzodiazepines, triazolam

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The application is directed to methods of sedating a pediatric subject by administering intravenously to the subject remimazolam, or a pharmaceutically acceptable salt thereof.
PCT/US2024/041709 2023-08-11 2024-08-09 Use of remimazolam for pediatric sedation Pending WO2025038446A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363519082P 2023-08-11 2023-08-11
US63/519,082 2023-08-11

Publications (2)

Publication Number Publication Date
WO2025038446A2 WO2025038446A2 (en) 2025-02-20
WO2025038446A3 true WO2025038446A3 (en) 2025-03-27

Family

ID=94633076

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2024/041709 Pending WO2025038446A2 (en) 2023-08-11 2024-08-09 Use of remimazolam for pediatric sedation

Country Status (1)

Country Link
WO (1) WO2025038446A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180312511A1 (en) * 2015-12-17 2018-11-01 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Short-acting benzodiazepine derivatives, preparation method therefor, and use thereof
WO2020193693A1 (en) * 2019-03-27 2020-10-01 Paion Uk Limited Medical uses for benzodiazepines with a particular eeg pattern
US20220001015A1 (en) * 2017-08-29 2022-01-06 Puretech Lyt, Inc. Lymphatic system-directing lipid prodrugs
US20220273672A1 (en) * 2016-04-14 2022-09-01 Paion Uk Limited Orally inhaled and nasal benzodiazepines
US20220402923A1 (en) * 2019-07-22 2022-12-22 Moehs Iberica S.L. Method for obtaining amorphous remimazolam besylate

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180312511A1 (en) * 2015-12-17 2018-11-01 Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. Short-acting benzodiazepine derivatives, preparation method therefor, and use thereof
US20220273672A1 (en) * 2016-04-14 2022-09-01 Paion Uk Limited Orally inhaled and nasal benzodiazepines
US20220001015A1 (en) * 2017-08-29 2022-01-06 Puretech Lyt, Inc. Lymphatic system-directing lipid prodrugs
WO2020193693A1 (en) * 2019-03-27 2020-10-01 Paion Uk Limited Medical uses for benzodiazepines with a particular eeg pattern
US20220402923A1 (en) * 2019-07-22 2022-12-22 Moehs Iberica S.L. Method for obtaining amorphous remimazolam besylate

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GARRETT ALEXANDREA, FLOWERS JESSIE, NG VANESSA, TOBIAS JOSEPH D: "Remimazolam for Sedation During Upper Gastrointestinal Endoscopy in an Adolescent", J MED CASES., vol. 13, no. 10, 31 October 2022 (2022-10-31), pages 495 - 498, XP093296305, DOI: 10.14740/jmc4013 *
RAMAMURTHI RADHAMANGALAM J., HAMMER GREGORY: "Remimazolam in Pediatric Anesthesia and Sedation", CURRENT ANESTHESIOLOGY REPORTS, SPRINGER US, vol. 13, no. 3, 1 September 2023 (2023-09-01), pages 165 - 171, XP093296303, ISSN: 2167-6275, DOI: 10.1007/s40140-023-00570-4 *

Also Published As

Publication number Publication date
WO2025038446A2 (en) 2025-02-20

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