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WO2025036514A3 - Pharmaceutical composition and use thereof - Google Patents

Pharmaceutical composition and use thereof Download PDF

Info

Publication number
WO2025036514A3
WO2025036514A3 PCT/CN2024/136831 CN2024136831W WO2025036514A3 WO 2025036514 A3 WO2025036514 A3 WO 2025036514A3 CN 2024136831 W CN2024136831 W CN 2024136831W WO 2025036514 A3 WO2025036514 A3 WO 2025036514A3
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical composition
phellandrene
myrcene
cymene
rhinovirus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/CN2024/136831
Other languages
French (fr)
Chinese (zh)
Other versions
WO2025036514A2 (en
Inventor
聂红梅
姜洪丽
王欢欢
张宁
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Grand Johamu Pharmaceutical Co Ltd
Original Assignee
Beijing Grand Johamu Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Grand Johamu Pharmaceutical Co Ltd filed Critical Beijing Grand Johamu Pharmaceutical Co Ltd
Priority to JP2024577155A priority Critical patent/JP7764639B2/en
Publication of WO2025036514A2 publication Critical patent/WO2025036514A2/en
Publication of WO2025036514A3 publication Critical patent/WO2025036514A3/en
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/14—Antitussive agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Provided are a pharmaceutical composition and a use thereof, wherein the pharmaceutical composition comprises α-pinene, p-cymene, β-myrcene, and β-phellandrene. The pharmaceutical composition has good inhibitory activity on rhinovirus and can be used for relieving cough symptoms.
PCT/CN2024/136831 2023-12-06 2024-12-04 Pharmaceutical composition and use thereof Pending WO2025036514A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2024577155A JP7764639B2 (en) 2023-12-06 2024-12-04 Pharmaceutical compositions and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202311656824.X 2023-12-06
CN202311656824.XA CN117338758B (en) 2023-12-06 2023-12-06 Pharmaceutical composition and application thereof

Publications (2)

Publication Number Publication Date
WO2025036514A2 WO2025036514A2 (en) 2025-02-20
WO2025036514A3 true WO2025036514A3 (en) 2025-04-24

Family

ID=89358004

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2024/136831 Pending WO2025036514A2 (en) 2023-12-06 2024-12-04 Pharmaceutical composition and use thereof

Country Status (3)

Country Link
JP (1) JP7764639B2 (en)
CN (3) CN117338758B (en)
WO (1) WO2025036514A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN117338758B (en) * 2023-12-06 2024-03-12 北京远大九和药业有限公司 Pharmaceutical composition and application thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102762218A (en) * 2009-09-29 2012-10-31 雷斯蒙农业合作社联盟 Compositions of botanical extracts and their use
CN109528649A (en) * 2019-01-15 2019-03-29 北京远大九和药业有限公司 A kind of terpenes pharmaceutical composition self-emulsifiable oral preparation and preparation method, application
CN110501442A (en) * 2018-05-17 2019-11-26 北京远大九和药业有限公司 A kind of detection method of impurity in eucalyptus oil or eucalyptol
WO2021191886A1 (en) * 2020-03-25 2021-09-30 Eybna Technologies Ltd. Compositions comprising terpenes and terpenoids and use thereof for preventing and treating viral-induced infections of the respiratory system
CN114601866A (en) * 2020-12-08 2022-06-10 北京远大九和药业有限公司 Composition for treating or preventing viral influenza and application thereof
US20230301935A1 (en) * 2019-05-28 2023-09-28 Tech Swerve Llc Penetrating topical pain relief compositions and methods of use
CN117338758A (en) * 2023-12-06 2024-01-05 北京远大九和药业有限公司 Pharmaceutical composition and application thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1674875A (en) * 2002-08-06 2005-09-28 奎格利公司 Anti-microbial compositions and methods of using same
PT2368547E (en) * 2010-03-26 2012-11-20 Cesa Alliance Sa Antiviral compositions comprising geraniol and carvone
TW202230163A (en) * 2020-10-14 2022-08-01 加拿大商Ｇｂｓ全球生物製藥公司 Method and systems for phytomedicine analytics for research optimization at scale
WO2022081037A1 (en) * 2020-10-16 2022-04-21 Herbelixa Doo Beograd-Novi Beograd Herbal preparation for prevention and treatment of helicobacter pylori infection
CN116963738A (en) * 2020-12-02 2023-10-27 麦翠奥制药公司 Luminol for the prevention and treatment of sequelae of SARS-CoV-2 infection
CN114870597A (en) * 2022-05-18 2022-08-09 上海启菲特环保生物技术有限公司 Plant-type deodorant for medical solid waste treatment and preparation method thereof
CN116473954A (en) * 2023-04-18 2023-07-25 颇黎芳香医药科技（上海）有限公司 A kind of external pharmaceutical composition for alleviating functional dyspepsia

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102762218A (en) * 2009-09-29 2012-10-31 雷斯蒙农业合作社联盟 Compositions of botanical extracts and their use
CN110501442A (en) * 2018-05-17 2019-11-26 北京远大九和药业有限公司 A kind of detection method of impurity in eucalyptus oil or eucalyptol
CN109528649A (en) * 2019-01-15 2019-03-29 北京远大九和药业有限公司 A kind of terpenes pharmaceutical composition self-emulsifiable oral preparation and preparation method, application
US20230301935A1 (en) * 2019-05-28 2023-09-28 Tech Swerve Llc Penetrating topical pain relief compositions and methods of use
WO2021191886A1 (en) * 2020-03-25 2021-09-30 Eybna Technologies Ltd. Compositions comprising terpenes and terpenoids and use thereof for preventing and treating viral-induced infections of the respiratory system
CN114601866A (en) * 2020-12-08 2022-06-10 北京远大九和药业有限公司 Composition for treating or preventing viral influenza and application thereof
CN117338758A (en) * 2023-12-06 2024-01-05 北京远大九和药业有限公司 Pharmaceutical composition and application thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BRUNO MARONGIU; SILVIA PORCEDDA; ALESSANDRA CAREDDA; BARBARA DE GIOANNIS; LAURA VARGIU; PAOLO: "Extraction of Juniperus oxycedrus ssp. oxycedrus essential oil by supercritical carbon dioxide: influence of some process parameters and biological activity", FLAVOUR AND FRAGRANCE JOURNAL., WILEY, NEW YORK, NY, GB, vol. 18, no. 5, 27 August 2003 (2003-08-27), GB , pages 390 - 397, XP071707637, ISSN: 0882-5734, DOI: 10.1002/ffj.1224 *
USHAKOV V.A., D.A. MURAV'EVA, L.A. BAKINA: "Monoterpene Compounds of the Essential Oils of Plants of the Genus Santolina", CHEMISTRY OF NATURAL COMPOUNDS, vol. 12, 1 September 1976 (1976-09-01), pages 597 - 598, XP093307104 *

Also Published As

Publication number Publication date
CN120093720A (en) 2025-06-06
CN117338758B (en) 2024-03-12
CN120093719A (en) 2025-06-06
CN117338758A (en) 2024-01-05
WO2025036514A2 (en) 2025-02-20
JP7764639B2 (en) 2025-11-05
JP2025529599A (en) 2025-09-05

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