[go: up one dir, main page]

WO2025003711A3 - Bioréacteur et microbe - Google Patents

Bioréacteur et microbe Download PDF

Info

Publication number
WO2025003711A3
WO2025003711A3 PCT/GB2024/051697 GB2024051697W WO2025003711A3 WO 2025003711 A3 WO2025003711 A3 WO 2025003711A3 GB 2024051697 W GB2024051697 W GB 2024051697W WO 2025003711 A3 WO2025003711 A3 WO 2025003711A3
Authority
WO
WIPO (PCT)
Prior art keywords
bioreactor
microorganism
microbe
biochemical
microbially
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/GB2024/051697
Other languages
English (en)
Other versions
WO2025003711A2 (fr
Inventor
David Ortega
Jin Xiang WONG
Koen SEMEIJN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Phase Biolabs Ltd
Original Assignee
Phase Biolabs Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB2309800.7A external-priority patent/GB202309800D0/en
Priority claimed from GBGB2309801.5A external-priority patent/GB202309801D0/en
Application filed by Phase Biolabs Ltd filed Critical Phase Biolabs Ltd
Publication of WO2025003711A2 publication Critical patent/WO2025003711A2/fr
Publication of WO2025003711A3 publication Critical patent/WO2025003711A3/fr
Anticipated expiration legal-status Critical
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/02—Photobioreactors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/06—Nozzles; Sprayers; Spargers; Diffusers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/20—Type of nucleic acid involving clustered regularly interspaced short palindromic repeats [CRISPR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/02—Acetobacter
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/145—Clostridium

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Sustainable Development (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

La présente invention concerne un bioréacteur comprenant, à l'intérieur d'une chambre, un micro-organisme génétiquement modifié, ledit micro-organisme comprenant les composants nécessaires à la conversion biochimique d'une source de carbone inorganique en acétyl-CoA, et un procédé de régulation dudit micro-organisme et ainsi de la production d'un produit biochimique produit par voie microbienne.
PCT/GB2024/051697 2023-06-28 2024-06-28 Bioréacteur et microbe Pending WO2025003711A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB2309801.5 2023-06-28
GBGB2309800.7A GB202309800D0 (en) 2023-06-28 2023-06-28 Control of microoganism
GBGB2309801.5A GB202309801D0 (en) 2023-06-28 2023-06-28 Bioreactor
GB2309800.7 2023-06-28

Publications (2)

Publication Number Publication Date
WO2025003711A2 WO2025003711A2 (fr) 2025-01-02
WO2025003711A3 true WO2025003711A3 (fr) 2025-02-06

Family

ID=91898151

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2024/051697 Pending WO2025003711A2 (fr) 2023-06-28 2024-06-28 Bioréacteur et microbe

Country Status (1)

Country Link
WO (1) WO2025003711A2 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009036095A1 (fr) * 2007-09-10 2009-03-19 Joule Biotechnologies, Inc. Organismes collecteurs de lumière synthétisés par génie génétique
WO2023118140A1 (fr) * 2021-12-23 2023-06-29 Phase Biolabs Ltd Système de fixation de carbone

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2009036095A1 (fr) * 2007-09-10 2009-03-19 Joule Biotechnologies, Inc. Organismes collecteurs de lumière synthétisés par génie génétique
WO2023118140A1 (fr) * 2021-12-23 2023-06-29 Phase Biolabs Ltd Système de fixation de carbone

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DEBABOV V. G.: "Acetogens: Biochemistry, Bioenergetics, Genetics, and Biotechnological Potential", MICROBIOLOGY, CONSULTANTS BUREAU, NEW YORK, NY, US, vol. 90, no. 3, 8 June 2021 (2021-06-08), pages 273 - 297, XP037475752, ISSN: 0026-2617, [retrieved on 20210608], DOI: 10.1134/S0026261721030024 *
POEHLEIN A. ET AL: "An ancient pathway combining carbon dioxide fixation with the generation and utilization of a sodium ion gradient for ATP synthesis", vol. 7, no. 3, 29 March 2012 (2012-03-29), pages 1 - 8, XP002715892, ISSN: 1932-6203, Retrieved from the Internet <URL:https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0033439> [retrieved on 20241023], DOI: 10.1371/JOURNAL.PONE.0033439 *

Also Published As

Publication number Publication date
WO2025003711A2 (fr) 2025-01-02

Similar Documents

Publication Publication Date Title
CN105378059B (zh) 产l-异亮氨酸微生物和使用该微生物生产l-异亮氨酸的方法
WO2005073390A3 (fr) Microorganisme produisant des acides amines l et procede de production de l’acide amine l
AU2019262112A8 (en) Engineered microorganism for the production of cannabinoid biosynthetic pathway products
MX2009010219A (es) Microorganismo modificado metabolicamente util para la produccion de 1,2-propanodiol.
MY174404A (en) Producing methionine without n-acyl-methionine
Górak et al. Application of cyanobacteria for chiral phosphonate synthesis
EP1641712A4 (fr) Production d&#39;hydrogene par photosynthese
MX2012006777A (es) Uso de promotores inducibles en la produccion de metionina.
WO2010027233A2 (fr) Nouvelle hydrogenase isolee a partir de thermococcus sp., gene la codant et procede de production d&#39;hydrogene au moyen de micro-organismes dotes de ce gene
WO2021191901A8 (fr) Production d&#39;acide lactique à partir de déchets organiques à l&#39;aide de compositions de spores de bacillus coagulans
WO2011036213A3 (fr) Processus de fermentation pour la production d&#39;acide glycolique
MX2022011594A (es) Sistemas y metodos de biofabricacion para producir productos organicos a partir de microorganismos recombinantes.
MX2021015192A (es) Metodo biocatalitico para la degradacion controlada de compuestos de terpeno.
WO2021160827A3 (fr) Production d&#39;un produit glycosylé dans des cellules hôtes
MY208546A (en) Method for controlling a fermentation process
WO2003016545A3 (fr) Procede de production de scleroglucane
EP2071019A8 (fr) Procédé pour la culture de micro-organismes de l&#39;ordre des Thraustochytriales
PH12022550956A1 (en) Method for enzymatically producing high-activity biological organic fertilizer
WO2025003711A3 (fr) Bioréacteur et microbe
WO2022221338A3 (fr) Systèmes, micro-organismes ou procédés de valorisation de déchets de pet
MY109170A (en) Process for production of amide compounds using agrobacterium radiobacter
EP4417060A3 (fr) Procédé de production de biomasse à l&#39;aide de bactéries oxydant l&#39;hydrogène
HRP20110366T1 (hr) Clostridium sartagoformum za proizvodnju bioplina
EP4133095A1 (fr) Procédé de préparation d&#39;acide phénylacétique
De Raadt et al. Microbial hydroxylation of 2-cycloalkylbenzoxazoles. Part I. Product spectrum obtained from Cunninghamella blakesleeana DSM 1906 and Bacillus megaterium DSM 32

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 24740526

Country of ref document: EP

Kind code of ref document: A2