WO2025098893A1 - Process tool unit - Google Patents

Abstract

The invention relates to a process tool unit (100) for producing a product, in particular a biological-pharmaceutical product, having: an interior (102) formed by a wall (104); at least one access device (106, 108) for providing access to the interior (102); and at least one tool unit (120, 122), in particular for treating an object (124, 126) which can be used to produce the product, said at least one tool unit (120, 122) being provided in the interior (102), and/or at least one sensor unit, in particular for analyzing an object (124, 126) which can be used to produce the product, said at least one sensor unit being provided in the interior (102), wherein the at least one tool unit (120, 122) and/or the at least one sensor unit (120) can be moved within the interior (102), and when access is provided, the at least one tool unit and/or the at least one sensor unit can be moved at least partly out of the interior (102) via the at least one access device (106, 108). The invention additionally relates to a combination of multiple process units (100, 156, 158) and to a process unit (156, 158) for producing a product, in particular a biological-pharmaceutical product.

Description

Tool process unit

The present invention relates to a tool process unit for producing a product, in particular a biological-pharmaceutical product.

Furthermore, the present invention relates to a combination of several process units, wherein at least one tool process unit is included, and the present invention further relates to a process unit for producing a product, in particular a biological-pharmaceutical product, which can be coupled to said tool process unit.

Particularly in the pharmaceutical sector, for example, for personalized therapeutics, multiple process units are often used to manufacture a biopharmaceutical product, enabling different and, in particular, individually tailored treatment processes to be carried out for the production of the product. These highly personalized therapeutics are therefore associated with high costs, particularly personnel costs, due to their individual and/or micro-production requirements, and there is often no possibility for large-scale application and/or industrial production of individual and/or micro-batch sizes.

The present invention is therefore based on the object of solving the aforementioned problem and, in particular, of providing a tool process unit for producing a product, in particular a biological-pharmaceutical product, by means of which such products can preferably be produced in an efficient and/or flexible manner.

This object is achieved according to the invention by the features of claim 1. Advantageous developments of the invention are described in the dependent claims.

A tool process unit according to the invention for producing a product, in particular a biological-pharmaceutical product, comprises: an interior formed by a wall; at least one access device for enabling access to the interior; and at least one tool unit, in particular for treating an object that can be used to produce the product, wherein the at least one tool unit is arranged in the interior, and/or at least one sensor unit, in particular for analyzing an object that can be used to produce the product, wherein the at least one sensor unit is arranged in the interior, wherein the at least one Tool unit and/or the at least one sensor unit is movable within the interior space and, when access is enabled via the at least one access device, is at least partially movable out of the interior space.

It can be provided that a particularly aseptic production area can be defined or is defined and/or formed by the interior of the tool processing unit. To a certain extent, it can be provided that the interior of the tool processing unit is a particularly aseptic production area.

In a sense, access to the interior can be access to the particularly aseptic production area.

It can be provided that the wall forming the interior space is designed as a thermal insulation element and/or comprises such a thermal insulation element and/or such a thermal insulation element is assigned to the wall. For example, the thermal insulation element can be designed as a foam-like and/or foamed insulation element. For example, the thermal insulation element can be arranged, for example fastened, directly or indirectly on the wall. For example, the thermal insulation element can be arranged inside or outside the interior space. This can preferably make it possible to achieve simple thermal decoupling of the interior space from the surroundings of the tool process unit.

For example, it can be provided that the wall is formed from several partial walls, between which one or the thermal insulation element is arranged. Optionally, a further thermal insulation element can be provided on the outside and/or inside. It is conceivable that a partial wall-insulation element-partial wall arrangement is provided, or a partial wall-insulation element-partial wall-insulation element arrangement is provided, etc. This can preferably achieve simple and efficient thermal decoupling of the interior from the surroundings of the tool processing unit.

For example, it may be provided that the tool processing unit comprises a temperature control device for controlling the temperature of the interior. Preferably, the temperature control device can be designed to cool the interior. It is understood that, additionally or alternatively, warming and/or heating the interior by means of the temperature control device may be conceivable. The temperature control device can be designed as an active and/or passive temperature control device.

It can be provided that a passive temperature control device can comprise one or more heat sinks for dissipating heat from the interior to the outside. A heat sink can be made of and/or contain aluminum, for example. A heat sink can, for example, comprise a plurality of cooling fins. This can preferably enable simple and cost-effective heat dissipation from the interior of the tool processing unit.

Additionally or alternatively, a passive temperature control device may comprise one or more cooling containers, in particular ice packs, with a pre-cooled content, for example, ice and/or a liquid, which can be arranged or are arranged in the interior. This preferably allows for simple and cost-effective cooling of the interior of the tool processing unit.

Additionally or alternatively, an active temperature control device can comprise an air circulation unit and one or more cooling containers, in particular cooling packs, with a pre-cooled content, for example ice and/or a liquid, wherein the cooling containers can be arranged or are arranged in the interior or in a further interior space spatially separated from the interior, and wherein the air circulation unit is arranged in the interior and/or between the interior and the further interior space in order to distribute and circulate air from the cooling containers in the interior, in particular evenly. The air circulation unit can be designed or comprise, for example, as a blower or fan. This can preferably achieve simple and cost-effective cooling of the interior of the tool processing unit with a more even temperature distribution.

Additionally or alternatively, an active temperature control device can comprise one or more temperature control units, in particular Peltier units, which can be arranged or are arranged in the interior. This can preferably achieve simple and, in particular, controllable cooling of the interior of the tool processing unit with a more uniform temperature distribution. Additionally or alternatively, an active temperature control device can comprise a fluid supply unit for supplying a cooling fluid into the interior space, a fluid discharge unit for discharging the cooling fluid from the interior space, and, optionally, a fluid line unit for conducting the fluid through the interior space, which is arranged between the fluid supply unit and the fluid discharge unit within the interior space. A cooling fluid can, for example, be gaseous, for example, air, and/or liquid. This can preferably enable highly efficient and, in particular, controllable cooling of the interior space of the tool processing unit with a more uniform temperature distribution.

It is understood that the tempering device can also be designed as a combination of the aforementioned embodiments of the tempering device.

It can be provided that a particularly lower, preferably lowest, floor surface of the interior is inclined relative to a plane oriented perpendicular to the direction of gravity. This allows liquids, such as condensate or cleaning fluid, to drain and/or collect in a targeted manner in the interior.

It can be provided that the tool process unit has on the inside and in particular the interior a lateral surface with a hygienic design, in particular a hygienic design, in which in particular no undercuts are provided on the inside and in particular on the lateral surface.

It can be provided that the tool processing unit is designed to be autoclavable on the inside and/or outside. In particular, the interior space, together with the components provided therein, preferably the at least one tool unit and/or the at least one sensor unit, can be designed to be autoclavable.

It can be provided that the access device comprises a door element which is arranged on and/or adjacent to the wall in the interior and which serves to open and close an access opening to the interior formed in the wall.

For example, it can be provided that the door element is movable, for example pivotable, in the direction of the interior for opening and closing. The tool processing unit may comprise a plurality of access devices, each of which enables access to the interior. It is understood that the tool processing unit may alternatively comprise exactly one access device.

It can be provided, for example, that the at least one tool unit and/or the at least one sensor unit can be moved at least partially out of the interior space when access is enabled via one and/or each of the access devices.

It can be provided that the tool process unit comprises a number, in particular a total number, of tool units and/or sensor units corresponding to the number of access devices.

Alternatively, it may be provided that the tool process unit comprises a smaller number, in particular a total number, of tool units and/or sensor units than the number of access devices.

Alternatively, it may be provided that the tool process unit comprises a larger number, in particular a total number, of tool units and/or sensor units than the number of access devices.

It can be provided that a respective tool unit and/or a respective sensor unit is assigned to one or more access devices in order to be movable at least partially out of the interior space, in particular via this access device or access devices.

It can be provided that a respective access device can be used to enable a respective access which is arranged along a height direction, in particular the

direction of gravity, or a direction perpendicular to it of the

tool process unit oriented.

For example, it may be provided that two or more access devices are provided, which are arranged on the same side, preferably the top or bottom, of the tool processing unit and/or on opposite sides, preferably the top and bottom, of the tool processing unit. For example, three access devices may be provided, of which two access devices are arranged on a bottom side of the tool processing unit, and an access device is arranged on a top side of the tool processing unit opposite the bottom side. It is understood that the aforementioned embodiment is exemplary and not exhaustive.

It can be provided that the tool processing unit, and in particular the at least one tool unit, comprises at least one handling device and a tool element held on the at least one handling device, which tool element can be moved within the interior space by means of the at least one handling device and, when access is enabled, out of the interior space via the at least one access device. For example, the tool element can be held on the handling device in a force-fitting and/or form-fitting manner and/or magnetically; for example, by means of clips and/or a screw connection and/or permanent magnets.

For example, it can be provided that the handling device is directly or indirectly attached to the wall within the interior space, in particular to a lateral side, top side, or bottom side of the interior space. Preferably, the handling device can be attached there so that it can be moved, in particular in one- or two-dimensionally movable manner.

The handling device can, for example, be a particularly motorized articulated arm or a multi-axis robot arm, and/or comprise such a robot arm. This preferably allows the tool element to be moved precisely within and out of the interior space. This can, for example, also serve to reduce the risk of contamination of the tool element.

The handling device can be, for example, a pick-and-place robot or a cable robot and/or comprise one of these.

The handling device can, for example, be a suitable gripper actuator arranged on a planar runner or a rail-guided gripper actuator, and/or comprise such a gripper actuator, wherein such a gripper actuator can be movable one-dimensionally or two-dimensionally along one side, in particular lateral side, top side or bottom side of the interior. For example, the planar slider may comprise a guide carriage that can be arranged or is arranged in the interior space and a magnetic drive for the guide carriage arranged outside the interior space, by means of which the guide carriage can be caused to move from the outside within the interior space, and in particular on an inner surface. The gripper actuator system can be provided, for example, on the guide carriage.

For example, it can be provided that the tool element is designed as a supply element and/or discharge element and/or comprises one by means of which a consumable, in particular a fluid, can be dispensed and/or absorbed. For example, such a tool element can be tubular, for example, as a hollow needle or injection needle or hose element or tubular element.

Additionally or alternatively, it can be provided, for example, that the tool element is designed as a removal element, in particular a sampling element, and/or comprises such a element, by means of which a part of an object that can be used to produce the product, e.g. a starting material and/or an intermediate product, or a product, in particular for sampling, can be picked up and/or grasped.

Additionally or alternatively, it can be provided, for example, that the tool element is designed as a manipulation element, in particular a sample manipulation element, and/or comprises such a manipulation element, by means of which a part of an object usable for producing the product, e.g., a reactant and/or an intermediate product, or a product, can be manipulated, in particular modified. Such manipulation can, for example, be carried out mechanically, electrically, magnetically, and/or radiation-based, and/or at least comprise a step based on these methods.

It can be provided that the tool process unit and in particular the at least one tool unit comprises and/or forms a fluid conveying device by means of which a fluid can be conveyed and/or caused to be conveyed, in particular via a tool element of the at least one tool unit.

For example, it can be provided that the fluid conveying device is designed as a pumping device and/or comprises one by means of which a fluid can be conveyed, in particular via a tool element of the at least one tool unit. For example, the pumping device can be designed as a peristaltic pump, diaphragm pump or piston pump.

Additionally or alternatively, it can be provided, for example, that the fluid conveying device is designed as a syringe device and/or comprises one by means of which a fluid can be conveyed, in particular via a tool element of the at least one tool unit.

For example, the syringe device can comprise at least one syringe element and at least one valve, which is fluidically arranged upstream and/or downstream of the syringe element for switching a fluid path relative to the syringe element. For example, the valve can be a 3-way valve, or two check valves can be provided, which can be arranged upstream and downstream of the syringe element, respectively. The syringe element can be designed as a single-use component or a multi-use component.

The syringe device can further comprise an actuating actuator by means of which the syringe device and in particular the syringe element can be actuated, in particular by means of which the syringe element can be pulled open and/or compressed for actuation. The syringe element can be held on the actuating actuator, for example, by means of a holder, in particular a holding contour, which is particularly adaptable to the syringe size. It is conceivable for the holder to be designed as a magnetic holder and/or to comprise such a holder. To a certain extent, it is conceivable for the syringe element to be held or retained based on magnetic force.

Additionally or alternatively, it can be provided, for example, that the fluid conveying device is designed as a valve device and/or comprises one by means of which a fluid can be conveyed, in particular via a tool element of the at least one tool unit. For example, the valve device can comprise one or more valves. A valve can in particular be designed as a shut-off valve and/or flow control valve for adjusting a flow, as a check valve for ensuring a flow direction, as a pressure valve for pressure-dependent adjustment of a flow, and/or as a directional control valve for dividing and/or merging one or more flows. It is understood that the valves comprised by the valve device can be different from one another and/or identical, or any combination is conceivable here. It can be provided that the pump device and/or the syringe device and/or the valve device is each designed as an exchangeable module which can be optionally installed and/or removed from the tool process unit.

It can be provided that the fluid conveying device comprises: a first tool element for fluid intake, into which a fluid for conveying can flow, and a second tool element for fluid discharge, from which a fluid can flow out again and which is fluidically connected directly or indirectly to the first tool element.

For example, it can be provided that an inflow opening of the first tool element is arranged or can be arranged higher with respect to the direction of gravity than an outflow opening of the second tool element. In this way, gravitational effects can be used, for example, to induce a corresponding flow from the inflow opening to the outflow opening. For example, in this case it can be provided that the tool process unit comprises several, for example two, access devices which are spaced apart from one another with respect to the direction of gravity. For example, a first access device can be provided on an upper side of the tool process unit and a second access device on an underside of the tool process unit.

Additionally or alternatively, it can be provided, for example, that the interior space is spatially separated and divided from one another by means of a partition wall into a first partial interior space and a second partial interior space.

A respective air pressure prevailing in the first partial interior space and the second partial interior space may differ from one another, wherein the first tool element may be arranged in the first partial interior space and the second tool element may be arranged in the second partial interior space for pressure difference-induced conveyance of a fluid from the first tool element to the second tool element.

It is understood that the tool processing unit may comprise a device for providing said pressure difference in the respective partial interior spaces and/or such a device may be associated or assigned to the tool processing unit. Furthermore, it is understood that the first and second tool elements are connected to one another by means of a fluid line that extends over and/or through the partition wall. For example, it can be provided that a pumping device, e.g. the pumping device, is arranged fluidically between the first tool element and the second tool element.

Additionally or alternatively, it can be provided, for example, that a syringe device, e.g. the syringe device, is arranged fluidically between the first tool element and the second tool element.

Additionally or alternatively, it can be provided, for example, that a valve device, e.g. the valve device, is arranged fluidically between the first tool element and the second tool element.

The fluid conveying device may include a sensor system by means of which one or more operating parameters of the fluid conveying device can be detected. For example, an operating parameter may be a pressure value within the fluid conveying device.

For example, an operating parameter can be a flow volume within the fluid conveying device. For example, an operating parameter can be a flow velocity within the fluid conveying device. It is understood that the sensor system can be configured to detect various operating parameters of the fluid conveying device.

It is conceivable that the sensor system comprises a pressure sensor, a load cell, strain gauges, a light barrier, etc., and/or that the sensor system comprises a sensor operating on magnetic principles, a sensor operating on optical principles, a sensor operating on capacitive principles, a sensor operating on acoustic principles, etc. It can be particularly advantageous if the sensor system comprises non-contact sensors, such as ultrasonic sensors and/or capacitive sensors.

It can be provided that the tool process unit and in particular the at least one tool unit comprises a fluid treatment device by means of which a fluid can be changed from a first state to a second state. For example, it may be provided that the fluid treatment device is arranged upstream or downstream of the fluid conveying device.

For example, it can be provided that the fluid treatment device is designed as a fluid dividing device and/or comprises one by means of which a fluid can be divided into at least two fluid parts, in particular sequentially and/or continuously.

In particular, the fluid dividing device may comprise one or more branching elements for dividing a fluid into multiple fluid parts. For example, a branching element may be a T- or Y-shaped conduit member for a fluid line and/or formed integrally with a fluid line.

In particular, the fluid distribution device may comprise one or more valves and/or one or more sensor units for detecting a fluid flow and/or fluid quantity and/or one or more fluid buffers.

For example, a valve and/or a sensor unit for detecting a fluid flow and/or fluid quantity and/or a fluid buffer can be arranged on and/or in a fluid line located downstream of the position of the fluid division. To a certain extent, any fluid line located downstream of the position of the fluid division can be provided with said components or any combination thereof. This preferably allows a respective fluid component to be monitored and/or fluidically controlled and/or treated.

Additionally or alternatively, it can be provided, for example, that the fluid treatment device is designed as a fluid mixing device and/or fluid mixing device and/or comprises one by means of which a fluid can be mixed and/or mixed with a further component, in particular a further fluid.

It can be provided that the fluid mixing device and/or fluid mixing device comprises at least one fluid reservoir and/or such a reservoir is assigned to it, for example the already described fluid intermediate reservoir, wherein the fluid can be mixed in the fluid reservoir and/or mixed with another component. In particular, the fluid mixing device and/or fluid mixing device can be designed as a vibration and/or shaking device and/or comprise such a device, by means of which the fluid can be mixed and/or mixed with another component. For example, the fluid reservoir can be movably arranged in and/or on the fluid mixing device and/or fluid mixing device and in particular the vibration and/or shaking device and can be caused to move by means of said mixing and/or mixing device. For example, a substrate on which the fluid reservoir is arranged can be moved in different directions, e.g., two-dimensionally or three-dimensionally, by means of said device, so that the contents of the fluid reservoir can be mixed and/or mixed. To a certain extent, the fluid mixing device and/or fluid mixing device can have a vibrating plate-like element on which the fluid reservoir can be arranged.

In particular, the fluid mixing device and/or fluid mixing device can be designed as a stirring device and/or comprise one by means of which the fluid can be thoroughly mixed and/or mixed with another component. For example, the fluid mixing device and/or fluid mixing device and in particular the stirring device can comprise a stirring drive by means of which a stirring element held or retained thereon can be driven, in particular in rotation, and/or which can be coupled to a stirring element integrated in and/or on the fluid reservoir for driving the same, in particular in rotation, wherein the stirring element can be arranged or is arranged in the fluid reservoir for mixing and/or mixing.

In particular, the fluid mixing device and/or fluid mixing device can be designed as a resuspension device and/or comprise one by means of which the fluid can be thoroughly mixed and/or mixed with another component. For example, the fluid mixing device and/or fluid mixing device and in particular the resuspension device can comprise a syringe element by means of which fluid can be removed from the fluid reservoir and released back into the fluid reservoir and/or another fluid reservoir in order to achieve mixing and/or mixing. For this purpose, said device can comprise an actuating unit and in particular actuating actuators. To a certain extent, mixing and/or mixing can be achieved by means of resuspension. It is understood that the syringe device described above can serve as a fluid mixing device and/or fluid mixing device and in particular as a resuspension device. In particular, the fluid mixing device and/or fluid mixing device can be designed as a magnetic stirring device and/or comprise one by means of which the fluid can be thoroughly mixed and/or mixed with another component. For example, the fluid mixing device and/or fluid mixing device can comprise a stirring magnetic element, in particular a magnetic stirring bar or stirring fish, and a magnetic drive unit for magnetically driving the stirring magnetic element. The stirring magnetic element can be arranged in the fluid reservoir and in particular in the fluid to be mixed or thoroughly mixed. The fluid reservoir can be arranged on and/or at the magnetic drive unit. The magnetic drive unit can be designed to move a drive magnet around the fluid reservoir, in particular tangentially, or to rotate a drive magnet below the fluid reservoir, whereby the stirring magnetic element can be caused to rotate or rotate within the fluid reservoir for mixing and/or thoroughly mixing the contents of the fluid reservoir.

In particular, the fluid mixing device and/or fluid mixing device can be designed as a pump device having a labyrinth fluid guide and/or can comprise such a pump device, by means of which the fluid can be mixed and/or mixed with another component. To a certain extent, the pump device can have a labyrinth fluid guide and/or can be assigned to it. For example, fluid can be pumped out of the fluid reservoir via a fluid line and, in particular, subsequently back in again by means of the pump device, wherein the labyrinth fluid guide can be provided in the fluid line and, in particular, can be integrated into the fluid line. For example, the labyrinth fluid guide can be designed as a meander-like fluid guide.

In particular, the fluid mixing device and/or fluid mixing device can be designed as and/or comprise a pulse device for exerting a mechanical pulse on the fluid reservoir, by means of which the fluid can be thoroughly mixed and/or mixed with another component. By means of the pulse device, a mechanical pulse can be exerted on the fluid reservoir, which can be arranged on and/or laterally with respect to the pulse device. To a certain extent, mixing and/or agitation of the contents of the fluid reservoir can be achieved by tapping from the side or bottom. Furthermore, adherent cells, for example, can preferably be released from a lateral surface of the fluid reservoir in this way.

Additionally or alternatively, it can be provided, for example, that the fluid treatment device is designed as a fluid separation device and/or such a by means of which a fluid can be separated into at least two components, in particular phase-dependent.

For example, the fluid separation device may comprise at least one of the following: a centrifuge device, a magnetic device, an osmosis device, a filter device, a membrane device, a countercurrent device, and/or a column device. The individual aforementioned devices for separating a fluid are known to those skilled in the art.

For example, it can be provided that the tool process unit comprises at least a number of access devices corresponding to the number of components of a fluid to be separated. This can, for example, enable a continuous or quasi-continuous release of the individual components from the interior via the respective access devices.

It can be provided that the tool processing unit and in particular the at least one sensor unit comprises at least one handling device and a sensor element held on the at least one handling device, which can be moved within the interior space by means of the at least one handling device and out of the interior space via the at least one access device when access is enabled. For example, the sensor element can be held on the handling device in a force-fitting and/or form-fitting manner and/or magnetically; for example, by means of clips and/or a screw connection and/or permanent magnets.

It is understood that the handling device of the sensor unit can be designed like the handling device of the tool unit described herein.

For example, it can be provided that a sensor unit is designed to determine one or more values of one or more parameters of a reactant and/or intermediate product and/or the finished product that can be used to produce the product.

For example, it can be provided that a sensor unit for determining a treatment progress during the treatment of a starting material and/or intermediate product and/or the finished product and/or designed to determine the treatment progress of said objects between two treatment processes.

Additionally or alternatively, it can be provided that the at least one sensor unit and the at least one tool unit have a common handling device by means of which a sensor element of the at least one sensor unit and/or a tool element of the at least one tool unit can be moved within the interior space and, when access is enabled, out of the interior space via the at least one access device.

It is understood that the common handling device can be designed like the handling device of the sensor unit described herein and/or like the handling device of the tool unit described herein.

It can be provided that the tool process unit comprises a storage device arranged in the interior for storing and/or temporarily storing fluid, by means of which a fluid can be provided for dispensing via the at least one tool unit and/or in which a fluid can be received via the at least one tool unit.

For example, the storage device can be formed by the fluid intermediate storage device already described and/or by the fluid storage device already described.

For example, it can be provided that the storage device comprises a disposable container, in particular a bag-like disposable container, and/or such a container can be fluidically and/or mechanically coupled to the storage device.

It can be provided that the tool process unit can be connected and in particular mechanically coupled to one or more further process units for producing a product, in particular a biological pharmaceutical product.

For example, it can be provided that the tool process unit can be connected simultaneously and, in particular, mechanically coupled to a number of further process units corresponding to the number of its own access devices. For example, it can be provided that a respective further process unit is designed as a treatment process unit, in particular for receiving and/or transporting and/or treating a reactant and/or intermediate product that can be used to produce the product and/or the finished product.

It can be provided that a design of a further process unit as a treatment process unit can correspond to a first configuration state.

Additionally or alternatively, it can be provided, for example, that a respective further process unit is designed as a supply process unit, in particular for storing and/or temporarily storing and/or for providing an object that can be used to manufacture the product, in particular a fluid.

It can be provided that the design of a further process unit as a supply process unit can correspond to a second configuration state.

For example, it may be provided that a process unit, and preferably the tool process unit, has one or more coupling devices by means of which this process unit can be connected, in particular mechanically coupled, to one or more further process units and/or to a storage device and/or a transport device of a production plant. For example, the coupling devices can be fully automatically operated. In other words, the connectable process units can be fully automatically connected to one another. It is conceivable that the coupling devices are designed as magnetic and/or positive and/or non-positive coupling devices.

It can be provided that the at least one tool unit and/or the at least one sensor unit can be moved at least partially out of the interior space and into the respective further process unit in the coupled state of the tool process unit and a respective further process unit and when access is enabled via the at least one access device.

The present invention further provides a combination of multiple processing units. This combination comprises: at least one tool process unit for producing a product, in particular a biological-pharmaceutical product, according to the preceding and/or the following description, and one or more further process units for producing a product, in particular a biological-pharmaceutical product, which is/are configured in particular according to the preceding and/or the following description.

It should be understood that all structural and/or functional features associated with the tool process unit according to the invention and its embodiments described above and/or below can also be included in said combination of multiple process units, either alone or in combination, and the associated properties, configurations and/or advantages can also be included and achieved accordingly.

Accordingly, a combination of several process units can comprise the following: at least one tool process unit for producing a product, in particular a biological-pharmaceutical product, according to the preceding and/or the following description, and one or more further process units for producing a product, in particular a biological-pharmaceutical product, wherein the at least one tool process unit and the one or more further process units are connectable to one another and in particular are mechanically connectable and/or coupled.

Preferably, the at least one tool unit and/or the at least one sensor unit of the at least one tool process unit can be moved at least partially out of the interior of the at least one tool process unit and into the respective further process unit in the coupled state and with access enabled.

For example, it can be provided that a further process unit of the combination is designed as a treatment process unit, e.g. a patient process unit, in particular for receiving and/or transporting and/or treating a treatment object.

It can be provided, for example, that a further process unit of the combination serves as a supply process unit, in particular for providing a material, e.g. a consumable material and/or a substance that may be required for treating a treatment object. Preferably, said material may be a fluid. To a certain extent, the supply process unit may be designed as a fluid process unit.

For example, said combination may comprise a plurality of additional processing units, wherein one or more additional processing units may each be configured as a treatment processing unit, and one or more additional processing units may each be configured as a supply processing unit. It is understood that all additional processing units may also be configured as treatment processing units or supply processing units.

For example, said combination may comprise two further process units, wherein a first further process unit may be designed as a treatment process unit and a second further process unit may be designed as a supply process unit.

It can be provided that a particularly aseptic transition between these process units can be made possible via respective access devices of process units coupled to one another, in particular tool process units and/or further process units.

It can be provided, for example, that the particularly aseptic transition between the tool process unit and a further process unit serves in particular to introduce said tool unit and/or said sensor unit at least partially into the further process unit, in particular to introduce it in a germ-free manner.

It can be provided, for example, that the particularly aseptic transition between the process units further serves to supply something, for example an object, preferably the said tool unit and/or the said sensor unit, a material and/or a substance, to one process unit from the other process unit, in particular to supply it temporarily and/or permanently, wherein at least one of the said process units can be the tool process unit.

The particularly aseptic transition between the said process units can be used bidirectionally and/or unidirectionally, for example for an exchange of anything between the process units. In other words, the particularly aseptic transition between the process units can be a bidirectional and/or a unidirectional transition. At least one of said process units can be the mold process unit.

For example, an object may include at least one of the following:

- a reactant, in particular a material containing cells, for example a starting material containing cells, and/or a biological-pharmaceutical material and/or a biological-pharmaceutical workpiece,

- an intermediate product, in particular a cell-containing intermediate product and/or a biological-pharmaceutical intermediate product,

- a product, for example the product to be manufactured, in particular a biological pharmaceutical product, for example the biological-pharmaceutical product to be manufactured,

- a consumable, for example a fluid and/or a component obtained or obtainable from a fluid.

It should be understood that the above list is exemplary and not exhaustive. Alternatively or additionally, the object may include one or more and/or a combination of the previously described enumeration elements.

The present invention further provides a process unit for producing a product, in particular a biological-pharmaceutical product. This process unit can, in particular, be a further process unit described herein.

Such a process unit for producing a product, in particular a biological-pharmaceutical product, can comprise the following: an interior space formed by a wall, in particular for receiving and/or transporting and/or treating an object; and at least one access device for enabling access to the interior space, wherein the process unit can be coupled to a tool process unit for producing a product, in particular a biological-pharmaceutical product, which tool process unit is preferably designed according to the preceding and/or following description, which tool process unit can be enabled to access the interior space via the at least one access device in the coupled state, wherein the process unit is designed in a first or a second configuration state and can be converted into the respective other configuration state. It can be provided that the process unit in the first configuration state is designed as a treatment process unit for receiving and/or transporting and/or treating a reactant and/or intermediate product that can be used to produce the product and/or the finished product.

In a sense, it can be provided that the process unit in the first configuration state is designed as a treatment process unit for receiving a reactant and/or intermediate product and/or the finished product that can be used to produce the product.

In a certain sense, it may additionally or alternatively be provided that the process unit in the first configuration state is designed as a treatment process unit for transporting a reactant and/or intermediate product and/or the finished product that can be used to produce the product.

In a certain sense, it may additionally or alternatively be provided that the process unit in the first configuration state is designed as a treatment process unit for treating a reactant and/or intermediate product that can be used to produce the product and/or the finished product.

It can be provided that the process unit in the second configuration state is designed as a supply process unit for storing and/or temporarily storing and/or for providing an object that can be used to manufacture the product, in particular a fluid.

In a sense, it can be provided that the process unit in the second configuration state is designed as a supply process unit for storing an object that can be used to produce the product, in particular a fluid.

In a sense, it can additionally or alternatively be provided that the process unit in the second configuration state is designed as a supply process unit for temporarily storing an object that can be used to produce the product, in particular a fluid.

In a sense, it can additionally or alternatively be provided that the process unit in the second configuration state acts as a supply process unit for providing a an object that can be used to produce the product, in particular a fluid.

It can be provided that each process unit comprises a wall which encloses and thereby defines the respective interior space and/or the respective interior.

A particularly aseptic production area can be defined or defined and/or formed by the interior and/or the interior of a process unit, in particular a further process unit and/or a tool process unit. To a certain extent, it can be provided that the interior and/or the interior of a process unit, in particular a further process unit and/or a tool process unit, is a particularly aseptic production area.

To a certain extent, the respective access device of the process unit, in particular of the further process unit and/or the tool process unit, can enable respective access to a respective, in particular aseptic, production area of the process unit.

It can be provided that a process unit, in particular a further process unit and/or a tool process unit, is movable and/or transportable and/or, in particular, automatically displaceable relative to its surroundings. It is understood that a process unit, in particular a further process unit and/or a tool process unit, can additionally or alternatively also be stationary relative to its surroundings.

It can be provided that in the said combination of several process units, one or more process units can be movable and/or transportable and/or in particular automatically movable and one or more process units can be stationary.

For example, a process unit, in particular a further process unit and/or a tool process unit, can comprise a transport vehicle, in particular a freely moving transport vehicle, or can be designed as such and/or can be coupled to a transport vehicle, in particular a freely moving transport vehicle. It can be provided that the transport vehicle, in particular a free-moving one, is guided by an induction loop and/or magnetically, in particular by permanent magnets and/or magnetic coils. Additionally or alternatively, sensor-based guidance, in particular camera-based guidance and/or radar/LIDAR-based guidance, can be provided.

Further preferred features and/or advantages of the present invention are the subject of the following description and the drawings of exemplary embodiments.

The figures show:

Fig. 1 is a schematic perspective view of a tool processing unit according to an exemplary embodiment of the present invention, wherein the tool processing unit is coupled to further processing units;

Fig. 2 is a schematic front view of the tool process unit of Fig. 1;

Fig. 3 is a further schematic front view of the tool process unit of Fig. 1;

Fig. 4 is a schematic sectional view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 5 is a schematic sectional view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 6 is a schematic sectional view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 7 is a schematic sectional view of a part of a tool process unit according to another exemplary embodiment of the present invention; Fig. 8 is a schematic sectional view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 9 is a schematic sectional view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 10 is a schematic sectional view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 11 is a schematic sectional view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 12 is a schematic sectional view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 13 is a schematic front view of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 14 is a schematic front view of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 15 is a schematic front view of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 16 is a schematic front view of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 17 is a schematic front view of a tool process unit according to another exemplary embodiment of the present invention; Fig. 18 is a schematic front view of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 19 is a schematic front view of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 20 is a schematic front view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 21 is a schematic diagram of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 22 is a schematic diagram of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 23 is a schematic diagram of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 24 is a schematic diagram of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 25 is a schematic diagram of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 26 is a schematic diagram of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 27 is a schematic diagram of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 28 is a schematic diagram of a tool process unit according to another exemplary embodiment of the present invention; Fig. 29 is a schematic front view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 30 is a schematic front view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 31 is a schematic front view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 32 is a schematic front view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 33 is a schematic front view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 34 is a schematic front view of a portion of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 35 is a schematic front view of a part of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 36 is a schematic front view of a tool process unit according to another exemplary embodiment of the present invention;

Fig. 37 is a schematic front view of a tool processing unit according to another exemplary embodiment of the present invention; and Fig. 38 is a schematic front view of a portion of a tool process unit according to another exemplary embodiment of the present invention.

Identical or functionally equivalent elements are provided with the same reference numerals in all figures.

Referring to Figs. 1 to 3, a tool process unit 100 according to an exemplary embodiment of the present invention is provided.

The tool process unit 100 is used to produce a product, in particular a biological-pharmaceutical product.

The tool process unit 100 has an interior space 102 which is formed by a wall 104.

In Figs. 1 to 3, a front side of the wall 104 is omitted for the purpose of description, in particular to illustrate the interior space 102.

The interior 102 of the tool processing unit 100 forms a particularly aseptic production area. In a sense, the interior 102 is a particularly aseptic production area.

Furthermore, the tool process unit 100 has a first access device 106 and a second access device 108, which can each selectively enable access to the interior 102.

To a certain extent, the first access device 106 and the second access device 108 can selectively enable respective access to the particularly aseptic production area.

The first and second access devices 106, 108 each have a first door element 110 and a second door element 112. The door elements 110, 112 serve to open and close a respective first and second access opening 114, 116 formed in the wall 104 to the interior 102.

The door elements 110, 112 can be pivoted into the interior space 102 for opening and can be pivoted back into the respective access opening 114, 116 for closing.

The first and second access devices 106, 108 are each motorized.

In the present embodiment, the access openings 114, 116 are formed in a lower section, in particular the lowest section, of the wall 104 with respect to the direction of gravity G.

In a sense, the access openings 114, 116 are formed in a bottom side 118 of the tool process unit 100.

Accordingly, the access devices 106, 108 are provided and particularly arranged on the underside 118 of the tool process unit 100.

By means of the access devices 106, 108, a respective access to the interior 102 along the direction of gravity G is possible.

As can be seen in the respective Figs. 1 to 3, the tool process unit 100 comprises a first tool unit 120 and a second tool unit 122.

In a sense, the tool process unit 100 comprises a number of tool units 120, 122 corresponding to the number of access devices 106, 108. It is understood that alternatively, a smaller or a larger number of tool units can also be provided.

The first and second tool units 120, 122 are used to treat an object 124, 126 that can be used to manufacture the product.

For example, an object 124, 126 may include at least one of the following: - a reactant, in particular a material containing cells, for example a starting material containing cells, and/or a biological-pharmaceutical material and/or a biological-pharmaceutical workpiece,

- an intermediate product, in particular a cell-containing intermediate product and/or a biological-pharmaceutical intermediate product,

- a product, for example the product to be manufactured, in particular a biological pharmaceutical product, for example the biological-pharmaceutical product to be manufactured,

- a consumable, for example a fluid and/or a component obtained or obtainable from a fluid.

It should be understood that the foregoing list is exemplary and not exhaustive. Alternatively or additionally, the object 124, 126 may comprise one or more and/or a combination of the previously described enumeration elements.

The first and second tool units 120, 122 are each arranged in the interior space 102.

The first tool unit 120 is arranged in the interior 102 corresponding to the first access device 106.

The second tool unit 122 is arranged in the interior 102 corresponding to the second access device 108.

It should be understood that with regard to the tool units 120, 122, additionally or alternatively at least one sensor unit, in particular for analyzing an object that can be used to manufacture the product, can be arranged in the interior space 102.

The first and second tool units 120, 122 are each movable within the interior space 102 and are each movable at least partially out of the interior space 102 when access is enabled via the first and second access devices 106, 108.

In this case, the first tool unit 120 can be moved at least partially out of the interior 102 when access is enabled via the first access device 106. In this case, the second tool unit 122 can be moved at least partially out of the interior 102 when access is enabled via the second access device 108.

Such mobility of the first and second tool units 120, 122 can be realized via a respective handling device, in particular a first handling device 128 of the first tool unit 120 and a second handling device 130 of the second tool unit 122.

In a sense, the first tool unit 120 comprises the first handling device 128 and the second tool unit 122 comprises the second handling device 130.

Furthermore, the first tool unit 120 comprises a first tool element 132, which is held on the first handling device 128 and which can be moved by means of the first handling device 128 within the interior 102 and, when access is enabled, out of the interior 102 via the first access device 106.

Furthermore, the second tool unit 122 comprises a second tool element 134, which is held on the second handling device 130 and which can be moved by means of the second handling device 130 within the interior 102 and, when access is enabled, out of the interior 102 via the second access device 108.

The respective tool elements 132, 134 are releasably held on the respective handling device 128, 130 via a force-locking and form-locking connection, in this case via a clamping device 136. The clamping device 136 can, for example, comprise clips for holding a tool element.

The first and second handling devices 128, 130 are each secured to the wall 104 within the interior space 102. In the present case, the first and second handling devices 128, 130 are secured to a lateral side and, in particular, the rear side 138 of the wall 104 and the interior space 102, respectively.

In the present embodiment, a further interior space 138 is provided in the tool process unit 100, which is arranged adjacent to the interior space 102 and is spatially separated from the interior space 102. □The further interior space 140 and the interior space 102 are separated from each other by a part of the wall 104, which can be assigned to the rear side of the interior space 102.

The further interior space 140 serves to receive and accommodate, in particular, temperature-sensitive and/or moisture-sensitive components, such as motors, circuit boards, etc., which can be or are assigned to the handling devices 128, 130 and/or the access devices 106, 108.

In a sense, the additional interior space 140 can be a type of technical box. This technical box 140 can, for example, be removable before autoclaving the remaining tool process unit 100 and/or can be insulated and/or cooled, in particular passively or actively cooled, in such a way that the said sensitive components are not damaged during autoclaving of the interior space 102.

As can be seen in Figs. 1 to 3, the first and second handling devices 128, 130 are each designed as an articulated arm 226.

In the present case, each articulated arm 226 comprises an arm member arranged on the rear side 138 of the interior 102, an arm member assignable to the tool element 132, 134, and an intermediate arm member arranged between said arm members.

The arm members are rotatable relative to one another and the arm member arranged on the rear side 138 of the interior 102 is rotatable relative to the rear side 138.

The first tool element 132 held on the first handling device 128 is designed as a feed element and/or discharge element, by means of which a consumable material and in particular a fluid can be dispensed and/or received.

In the present embodiment, the first tool element 132 is tubular and in particular needle-like.

The second tool element 134 held on the second handling device 130 is designed as a feed element and/or discharge element, by means of which a consumable material and in particular a fluid can be dispensed and/or received. In the present embodiment, the second tool element 134 is tubular and in particular needle-like.

It is understood that the first and second tool elements 132, 134 can serve as a removal element and in particular as a sampling element and/or can be designed as such.

As can be seen in Fig.1 to 3, the tool process unit 100 comprises a fluid conveying device 142, which is arranged in the interior 102 and by means of which a fluid can be conveyed.

The fluid conveying device 142 can be assigned or associated with the first and/or second tool unit 120, 122.

In the present embodiment, the fluid conveying device 142 is designed as a syringe device 144.

The syringe device 144 is at least partially designed as an exchangeable module which can be optionally installed and/or removed from the tool process unit 100.

The syringe device 144 is fluidically arranged between the first tool element 132 and the second tool element 134.

The syringe device 144 comprises a syringe element 146, a valve 148 designed as a 3-way valve and an actuating actuator 150.

The first tool element 132 is fluidly connected to the valve 148 and the second tool element 134 is fluidly connected to the valve 148.

Furthermore, the syringe element 146 is fluidly connected to the valve 148.

The valve 148 is fluidically arranged upstream of the syringe element 146 for switching a fluid path relative to the syringe element 146 and in particular a fluid path between the first tool element 132 and the second tool element 134. For example, by means of the valve 148, fluid intake into the syringe element 146 via the first tool element 132 or via the second tool element 134 is possible depending on a switching state of the valve 148.

For example, by means of the valve 148, a fluid discharge from the syringe element 146 via the first tool element 132 or via the second tool element 134 is possible depending on a switching state of the valve 148.

By means of the actuating actuator 150, the syringe element 146 can be actuated and, in particular, can be pulled open for fluid intake into the syringe element 146 and compressed for fluid discharge from the syringe element 146.

For this purpose, the actuating actuator 150 comprises a pivoting arm 152 for pulling up and/or compressing the syringe element 146 and a holder 154, in particular adjustable to the syringe size, for holding the syringe element 146.

To a certain extent, depending on the switching state of the valve 148 and/or actuation of the syringe element 146, fluid can flow into the first or second tool element 132, 134 by means of the actuation actuator 150 for fluid intake or can flow out again for fluid discharge.

It can also be provided that the underside 118 of the interior 102 is inclined relative to a plane oriented perpendicular to the direction of gravity G. As a result, liquids, for example condensation water from the syringe element 146 or cleaning fluid, can preferably be drained and/or collected in the interior 102 in a targeted manner.

It can also be provided that the tool process unit 100 on the inside and in particular the interior 102 has a lateral surface with a hygienic design, in particular a hygienic design, in which in particular no undercuts are provided on the inside and in particular on the lateral surface side.

It can further be provided that the tool process unit 100 is designed to be autoclavable on the inside and/or outside. As can be seen in Figs. 1 to 3, the tool process unit 100 can be connected and in particular mechanically coupled to one or more further process units 156, 158 for producing a product, in particular a biological-pharmaceutical product.

In the present embodiment, the tool process unit 100 is coupled to two further process units 156, 158.

It is understood that the tool process unit 100 and the further process units 156, 158 have one or more coupling devices not shown in the figures, by means of which these process units 100, 156, 158 can be coupled to one another and/or to one another and/or can be connected to a storage device and/or a transport device of a production plant.

As can be seen in the figures, the tool process unit 100 can be connected simultaneously and, in particular, mechanically coupled to a number of further process units 156, 158 corresponding to the number of its own access devices 106, 108.

A further process unit 156 is designed as a treatment process unit 156 for receiving and/or transporting and/or treating a reactant and/or intermediate product 124 that can be used to produce the product.

To a certain extent, in the present embodiment, an object 124 can be, for example, a reactant and/or intermediate product 124.

The reactant and/or intermediate product 124 is presently arranged in a first container 160, which is arranged in the treatment process unit 156.

The other further process unit 158 is designed as a supply process unit 158 for storing and/or temporarily storing and/or providing a fluid 126 that can be used to produce the product.

In a sense, the supply process unit 158 in the present embodiment can be understood as a fluid process unit. In a sense, in the present embodiment, an object 126 may be, for example, a fluid 126.

The fluid 126 is arranged in a second container 162 which is arranged in the supply process unit 158.

In the present embodiment, the treatment process unit 156 is coupled to the tool process unit 100 in the area of the first access device 106.

It is understood that the treatment process unit 156 is provided with a counter access device corresponding to the first access device 106 for enabling access to the interior 164 of the treatment process unit 156.

This can be understood in particular to mean that the treatment process unit 156 has an interior space 164 formed by a wall 168.

In the present embodiment, the supply process unit 158 is coupled to the tool process unit 100 in the area of the second access device 108.

It is understood that the supply process unit 158 is provided with a counter access device corresponding to the second access device 108 for enabling access to the interior 166 of the supply process unit 158.

This can be understood in particular to mean that the supply process unit 158 has an interior space 166 formed by a wall 170.

A particularly aseptic transition between these process units 100, 156, 158 is possible via the respective access devices 106, 108 or counter-access devices of the coupled tool process unit 100 and further process units 156, 158.

The particularly aseptic transition between these process units 100, 156, 158 serves, for example, to supply something, preferably one of the said tool units 120, 122 and/or a sensor unit, a material and/or a substance, to one of the said process units from another of the said process units, in particular to supply it temporarily and/or permanently. The particularly aseptic transition between these process units 100, 156, 158 serves, for example, to be able to introduce the said tool units 120, 122 at least partially into the further process units 156, 158, in particular to introduce them in a germ-free manner.

In other words, the first and second tool units 120, 122 and in the present case the first and second tool elements 132, 134, in the coupled state of the tool process unit 100 and the respective further process units 156, 158 and when access is enabled via the respective access devices 106, 108 or counter-access devices, are at least partially movable out of the interior 102 of the tool process unit 100 and into the respective further process unit 156, 158 and in the present case into their respective interior spaces 164, 166.

It is understood that the particularly aseptic transition between these process units 100, 156, 158 can be used bidirectionally and/or unidirectionally.

In the present exemplary embodiment, the further process units 156, 158 are movable and/or transportable and/or in particular automatically movable relative to their surroundings.

In the present exemplary embodiment, the tool processing unit 100 is stationary relative to its surroundings. It is understood that the tool processing unit 100 can also be designed to be movable and/or transportable and/or, in particular, automatically movable relative to its surroundings.

For example, a process unit 100, 156, 158, in particular a further process unit 156, 158 and/or a tool process unit 100, can comprise a particularly freely moving transport vehicle or can be designed as such and/or can be coupled to a particularly freely moving transport vehicle and/or a transport device of a production plant.

A possible exemplary operation of the tool process unit 100 will be described below: The tool process unit 100 is provided stationary with respect to its environment, for example a production plant.

The further process units 156, 158 are provided in a movable and/or transportable and/or in particular automatically movable manner with respect to the said environment, for example the production plant.

The further process units 156, 158 move actively and/or passively towards the tool process unit 100 for a corresponding coupling.

After coupling has taken place, the treatment process unit 156 is coupled to the tool process unit 100 in the area of the first access device 106 and the supply process unit 158 is coupled to the tool process unit 100 in the area of the second access device 108.

Now, via the respective access devices 106, 108 or counter-access devices of the coupled tool process unit 100 and further process units 156, 158, a particularly aseptic transition between these process units 100, 156, 158 is possible.

As can be seen in Fig. 3, the first door element 110 pivots from a closed state (see dashed contour) into the interior space 102 into an open state. A corresponding opening of the counter access device of the treatment process unit 156 also occurs.

Subsequently, the first tool element 132 can be or will be moved out of the interior 102 of the tool processing unit 100 by means of the first handling device 128 and into the interior 164 of the treatment processing unit 156.

The initial state (cf. dashed contour) and the final state, between which the first handling device 128 moves with the first tool element 132, is shown as an example in Fig. 3. In particular, the first tool element 132 is introduced into the first container 160 and into the reactant and/or intermediate product 124 arranged in the first container 160 for fluid intake or fluid discharge (see Fig. 3).

Parallel to this or subsequently, or conceivably also before, the second door element 112 pivots from a closed state into the interior 102 into an open state (see dashed contour). A corresponding opening of the counter access device of the supply process unit 158 also occurs.

Subsequently, the second tool element 134 can be or will be moved out of the interior 102 of the tool processing unit 100 by means of the second handling device 130 and into the interior 166 of the supply processing unit 158. This occurs in a manner analogous to the movement of the first handling device 128, which is illustrated as an example in Fig. 3.

In particular, the second tool element 134 is introduced into the second container 162 and into the fluid 126 arranged in the second container 162 for fluid intake or fluid discharge. This occurs in a manner analogous to the first tool element 132, which is shown as an example in Fig. 3.

Subsequently, fluid 126 can be conveyed from the second container 162 to the reactant and/or intermediate product 124 in the first container 160 by means of the syringe device 144, or reactant and/or intermediate product 124 can be conveyed from the first container 160 to the fluid 126 in the second container 162 by means of the syringe device 144.

For this purpose, the valve 148 switches to a switching state which corresponds to the intended conveying direction, and the pivot arm 152 pulls the syringe element 146 apart so that the object 124, 126 to be conveyed is picked up from the corresponding container 160, 162 via the corresponding tool element 132, 134 in the syringe element 146.

Subsequently, the valve 148 switches to a further switching state, which is inverse to the previously mentioned switching state, and the pivot arm 152 compresses the syringe element 146 so that the object 124, 126 to be conveyed is dispensed from the syringe element 146 into the corresponding container 160, 162 via the corresponding tool element 132, 134. After completion of such a conveying process, the tool elements 132, 134 are moved back into the interior 102 by means of the handling devices 128, 130.

The respective interior spaces 102, 164, 166 of the involved process units 100, 156, 158 are again closed by means of the access devices 106, 108 or door elements 110, 112 and counter access devices.

The treatment process unit 156 and the supply process unit 158 can be moved away from the tool process unit 100 again.

Such a described conveying process can be one of several treatment processes for producing a product, in particular a biological-pharmaceutical product. Several treatment processes in a defined sequence can define a complete manufacturing process for the product, in particular the biological-pharmaceutical product. To a certain extent, the defined sequence of treatment processes can reflect a recipe for producing the product, in particular the biological-pharmaceutical product.

In Fig. 4, a schematic sectional view of a part, in particular the wall 104, of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 4 is essentially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 1, so that only the differences are described below.

For descriptive purposes, Fig. 4 specifically depicts the part or component exhibiting differences, here wall 104. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 4, the wall 104 forming the interior space 102 comprises a thermal insulation element 172.

The thermal insulation element 172 is arranged on the wall 104. In particular, the thermal insulation element 172 is arranged on the inside of the wall 104 with respect to the interior space 102.

The thermal insulation element 172 is designed as a foam-like and/or foamed insulation element.

The thermal insulation element 172 can preferably be used to realize a simple thermal decoupling of the interior 102 from an environment of the tool process unit 100.

In Fig. 5, a schematic sectional view of a part, in particular the wall 104, of a tool process unit 100 according to a further exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 5 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 1 and/or in Fig. 4, so that only the differences are described below.

For descriptive purposes, Fig. 5 specifically depicts the part or component exhibiting differences, in this case wall 104. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 5, the wall 104 comprises several partial walls 174, 176, in particular a first partial wall 174 and a second partial wall 176.

The thermal insulation element 172 is arranged between the first and second partial walls 174, 176.

Furthermore, a further thermal insulation element 178 is arranged on the second partial wall 176.

In particular, the further thermal insulation element 178 is arranged on the inside of the second partial wall 176 with respect to the interior space 102. In a sense, the wall 104 is constructed starting from the interior space 102, in particular by the further thermal insulation element 178, the second partial wall 176, the thermal insulation element 172 and the first partial wall 174. This can be understood in particular as a multi-layer arrangement.

The thermal insulation element 172 and the further thermal insulation element 178 are each designed as a foam-like and/or foamed insulation element.

By means of the thermal insulation element 172 and the further thermal insulation element 172 and in particular the multi-layer arrangement of the wall 104, an improved thermal decoupling of the interior 102 from an environment of the tool process unit 100 can preferably be realized.

In Fig. 6, a schematic sectional view of a part, in particular the wall 104, of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 6 is essentially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 4, so that only the differences are described below.

For descriptive purposes, the part showing differences has been shown in Fig. 6. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 6, the tool process unit 100 further comprises a tempering device 180 for tempering the interior space 102.

Advantageously, the temperature control device 180 serves to cool the interior 102.

In the present embodiment, the tempering device 180 is designed as a passive tempering device.

The passive temperature control device 180 is designed as a cooling container 182, for example as a cooling pack, with a pre-cooled content, for example ice and/or a liquid. The cooling container 182 can be arranged in the interior 102 and/or is already arranged in this case.

This preferably makes it possible to realize simple and cost-effective cooling of the interior 102 of the tool process unit 100.

In Fig. 7, a schematic sectional view of a part, in particular the wall 104, of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 7 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 4, so that only the differences are described below.

For descriptive purposes, the part showing differences has been shown in Fig. 7. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 7, the tool process unit 100 further comprises a tempering device 180 for tempering the interior space 102.

Advantageously, the temperature control device 180 serves to cool the interior 102.

In the present embodiment, the tempering device 180 is designed as an active tempering device.

The active temperature control device 180 comprises a plurality of temperature control units 184 arranged in the interior space 102. By way of example, four temperature control units 184 are provided in the present exemplary embodiment.

In the present embodiment, the temperature control units 184 are arranged in pairs opposite each other on the wall 104 and in particular on the insulation element 172. This arrangement can, for example, serve to achieve a more uniform temperature distribution. The temperature control units 184 are each designed as Peltier units.

As a result, preferably a simple and in particular controllable cooling of the interior 102 of the tool process unit 100 can be realized with a more uniform temperature distribution.

In Fig. 8, a schematic sectional view of a part, in particular the wall 104, of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 8 is essentially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 4, so that only the differences are described below.

For descriptive purposes, the part showing differences has been shown in Fig. 8. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 8, the tool process unit 100 further comprises a tempering device 180 for tempering the interior space 102.

Advantageously, the temperature control device 180 serves to cool the interior 102.

In the present embodiment, the tempering device 180 is designed as a passive tempering device.

The passive temperature control device 180 comprises two heat sinks 186, which are arranged at least partially in the interior space 102. In a sense, the passive temperature control device 180 is formed by the two heat sinks 186.

The heat sinks 186 serve to dissipate heat from the interior 102. The heat sinks 186 extend through the wall 104 and the insulation element 172 and outwardly relative to the interior space 102 in order to enable heat to be dissipated from the interior space 102 to the outside.

A respective heat sink 186 is manufacturable or manufactured from aluminum and/or contains aluminum.

A respective heat sink 186 comprises a plurality of cooling fins not shown in the figure in order to be able to realize efficient heat dissipation.

This preferably makes it possible to achieve simple and cost-effective heat dissipation from the interior 102 of the tool process unit 100.

In Fig. 9, a schematic sectional view of a part, in particular the wall 104, of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 9 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 4, so that only the differences are described below.

For descriptive purposes, the part showing differences has been shown in Fig. 9. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 9, the tool process unit 100 further comprises a tempering device 180 for tempering the interior space 102.

Advantageously, the temperature control device 180 serves to cool the interior 102.

As can be seen in Fig. 9, the interior space 102 in the present embodiment is divided into a first thermal partial interior space 188 and a second thermal partial interior space 190, which are separated from one another by a thermal partition wall 192. The thermal separation wall 192 is formed by a portion of the insulation element 172. In a sense, the first thermal partial interior space 188 and the second thermal partial interior space 190 are also thermally separated and/or shielded from each other in this way.

The first thermal partial interior 188 is configured in particular like the interior 102 described in connection with the embodiment of Figs. 1 to 3; i.e., in particular, that the at least one, here first and second, access device 106, 108 and the at least one, here first and second, tool unit 120, 122 are provided in the first thermal partial interior 188.

In the present embodiment, the tempering device 180 is designed as an active tempering device.

The active temperature control device 180 comprises an air circulation unit 194 and a cooling container 182, which are arranged within the tool process unit 100.

The cooling container 182 can be arranged in the second thermal partial interior space 190 and/or is already arranged therein.

The cooling container 182, for example designed as a cooling pack, can be filled or is filled with a pre-cooled content, for example ice and/or a liquid.

The cooling container 182 thus cools the air in the second thermal partial interior space 190. In a sense, cooled air is present in the second thermal partial interior space 190.

The air circulation unit 194 is arranged in the first thermal sub-interior 188.

The air circulation unit 194 is designed as a fan.

The air circulation unit 194 serves to convey cooled air from the second thermal sub-interior 190 into the first thermal sub-interior 188 for cooling the same, and to convey warmer air than the cooled air from the first thermal sub-interior 188 into the second thermal sub-interior 190 for cooling the same. For this purpose, a first passage line 196 and a second passage line 198 are arranged and set up in the thermal separation wall 192.

The first passage line 196 serves to supply air from the first thermal partial interior space 188 into the second thermal partial interior space 190 and the second passage line 198 serves to supply air from the second thermal partial interior space 190 into the first thermal partial interior space 188.

In a sense, such a cooling circuit can be realized by the air flow, which can be guided through the first thermal partial interior space 188, the first passage line 196, the second thermal partial interior space 190 and the second passage line 198.

As a result, preferably a simple and cost-effective cooling of the interior 102 or the first thermal partial interior 188 of the tool process unit 100 can be realized with a more uniform temperature distribution.

In Fig. 10, a schematic sectional view of a part, in particular the wall 104, of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 10 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 4, so that only the differences are described below.

For descriptive purposes, the part showing differences has been shown in Fig. 10. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 10, the tool process unit 100 further comprises a tempering device 180 for tempering the interior space 102.

Advantageously, the temperature control device 180 serves to cool the interior 102.

In the present embodiment, the tempering device 180 is designed as an active tempering device. The active temperature control device 180 comprises a fluid supply unit 200 for supplying a cooling fluid into the interior space 102 and a fluid discharge unit 202 for discharging the cooling fluid from the interior space 102.

The cooling fluid is gaseous and air.

The fluid supply unit 200 and the fluid discharge unit 202 are fluidically connectable and/or presently connected to a cooling unit 204 of the temperature control device 180.

The cooling unit 204 is provided outside the interior space 102 on and/or in the tool process unit 100.

The fluid supply unit 200 serves to supply cooled air from the cooling unit 204 into the interior 102 and the fluid discharge unit 202 serves to supply air from the interior 102 to the cooling unit 204, for example.

To a certain extent, such a cooling circuit can be realized by the air flow, which can be guided through the interior 102, the fluid discharge unit 202, the cooling unit 204 and the fluid supply unit 200.

As a result, preferably a highly efficient and in particular controllable cooling of the interior 102 of the tool process unit 100 can be realized with a more uniform temperature distribution.

In Fig. 11, a schematic sectional view of a part, in particular the wall 104, of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 11 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 10, so that only the differences are described below. For descriptive purposes, the part showing differences has been shown in Fig. 11. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 11, the tool process unit 100 can be arranged stationary with respect to its surroundings.

For this purpose, the tool process unit 100 can advantageously be coupled and is coupled in the present case to a coupling device 206, for example, a preferably higher-level production system.

The active temperature control device 180 of the tool processing unit 100 comprises a fluid supply unit 200 for supplying a cooling fluid into the interior space 102 and a fluid discharge unit 202 for discharging the cooling fluid from the interior space 102.

The cooling fluid is gaseous and air.

The fluid supply unit 200 and the fluid discharge unit 202 are fluidically connectable to a cooling unit of the coupling device 206 (not shown in the figure) and are connected in the coupled state in the present case.

By means of the cooling unit 204 of the coupling device 206, cooled air can be fed from the cooling unit via the fluid supply unit 200 into the interior 102 and air can be fed from the interior 102 via the fluid discharge unit 202, for example back to the cooling unit 204.

To a certain extent, such a cooling circuit can be realized by the air flow, which can be guided through the interior 102, the fluid discharge unit 202, the cooling unit of the coupling device 206 and the fluid supply unit 200.

As a result, preferably a highly efficient and in particular controllable cooling of the interior 102 of the tool process unit 100 can be realized with a more uniform temperature distribution. In Fig. 12, a schematic sectional view of a part, in particular the wall 104, of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 12 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 10, so that only the differences are described below.

For descriptive purposes, the part showing differences has been shown in Fig. 12. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 12, the tool process unit 100 further comprises a tempering device 180 for tempering the interior space 102.

Advantageously, the temperature control device 180 serves to cool the interior 102.

In the present embodiment, the tempering device 180 is designed as an active tempering device.

The active temperature control device 180 comprises a fluid supply unit 200 for supplying a cooling fluid into the interior space 102, a fluid line unit 208 for guiding the fluid through the interior space 102, and a fluid discharge unit 202 for discharging the cooling fluid from the interior space 102.

The fluid supply unit 200, the fluid line unit 208 and the fluid discharge unit 202 are formed integrally with one another or are fluidically tightly connected to one another.

The fluid supply unit 200, the fluid line unit 208 and the fluid discharge unit 202 form a common fluid guide into the interior space 102, through the interior space 102 and out of the interior space 102.

The cooling fluid is liquid in this case, although a gaseous cooling fluid may also be conceivable as an alternative. The fluid supply unit 200 and the fluid discharge unit 202 are fluidically connectable and presently connected to a cooling unit 204 of the temperature control device 180.

The cooling unit 204 is provided outside the interior space 102 on and/or in the tool process unit 100.

The fluid supply unit 200 serves to supply cooled cooling fluid from the cooling unit 204 into the interior 102.

The fluid line unit 208 serves to guide this cooling fluid through the interior 102 in order to cool it.

The fluid discharge unit 202 serves to supply this cooling fluid from the interior 102 to the cooling unit 204, for example, again.

To a certain extent, such a cooling circuit can be realized by the cooling fluid flow, which can be guided via the fluid line unit 208 through the interior 102, the fluid discharge unit 202, the cooling unit 204 and the fluid supply unit 200.

As a result, preferably a highly efficient and in particular controllable cooling of the interior 102 of the tool process unit 100 can be realized with a more uniform temperature distribution.

Referring to Figs. 4 to 12, it is understood that the temperature control device 180 can also be designed as a combination of the exemplary embodiments of Figs. 4 to 12. It is also understood that in the exemplary embodiments of Figs. 4 to 12, additionally or alternatively, warming and/or heating of the interior 102 by means of the temperature control device 180 can be conceivable, or the temperature control device 180 is designed for this purpose.

In Fig. 13, a schematic front view of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 13 is substantially configured and/or designed like the embodiments of the tool process unit 100 shown in Figs. 1 to 3 and/or any of the embodiments of the tool process unit 100 shown in Figs. 4 to 12, so that only the differences are described below. In the present embodiment, the access openings 114, 116 are formed on mutually opposite sections of the wall 104 with respect to the direction of gravity G.

In the present case, the first access opening 114 is formed in a top side 210 of the tool process unit 100 and the second access opening 116 is formed in the bottom side 118 of the tool process unit 100.

Accordingly, the access devices 106, 108 are provided and in particular configured on the upper side 210 and on the lower side 118 of the tool process unit 100, respectively.

By way of example, the first door element 110 is shown in an open state and a closed state (see dashed line) and the second door element 112 is shown in an open state (see dashed line) and a closed state.

By means of the access devices 106, 108, a respective access to the interior 102 along the direction of gravity G on opposite sides 118, 210 of the tool process unit 100 is possible.

In a sense, the first and second access devices 106, 108 are arranged at a distance from each other with respect to the direction of gravity G.

The first handling device 128 is arranged relative to the first access device 106 in an analogous manner to the second handling device 130 relative to the second access device 108.

In the present embodiment, the fluid conveying device 142 is formed by the fluidically interconnected tool elements 132, 134.

The first tool element 132 serves to receive fluid and a fluid can flow into it for conveying.

The second tool element 134 serves to discharge fluid and a fluid can flow out of it again. In a sense, the fluid conveying device 142 has the first tool element 132 for fluid intake, into which a fluid can flow for conveyance, and the second tool element 134 for fluid discharge, from which the fluid can flow out again and which is fluidically connected to the first tool element 132.

As can be seen in Fig. 13, an inflow opening 212 of the first tool element 132 is arranged or can be arranged higher with respect to the direction of gravity G than an outflow opening 214 of the second tool element 134.

This allows gravitational effects to be used to induce a corresponding fluid flow from the inlet opening 212 to the outlet opening 214.

If the respective access devices 106, 108 or

Counter access devices of the coupled tool process unit 100 and further process units 156, 158 enable a particularly aseptic transition between these process units 100, 156, 158, the first tool element 132 can be moved out of the interior 102 of the tool process unit 100 by means of the first handling device 128 and into the interior 164 of the treatment process unit 156.

The second tool element 134 can be moved out of the interior 102 of the tool process unit 100 by means of the second handling device 130 and into the interior 166 of the supply process unit 158.

In particular, the second tool element 134 is inserted into the second container 162 for fluid dispensing, such that at least the outflow opening 214 of the second tool element 134 is inserted into the second container 162 for fluid dispensing.

The first tool element 132 is introduced into the first container 160 and into the reactant and/or intermediate product 124 arranged in the first container 160 for fluid absorption.

For this purpose, the first container 160 has a corresponding connection on the underside (not shown in the figure), via which access for the first tool element 132 is possible. Educt and/or intermediate product 124, which in the present embodiment is fluidic or at least has fluid properties, can now be conveyed by gravity from the first container 160 in the direction of the second tool element 134 and finally into the second container 162 via the inflow opening 212 of the first tool element 132.

There, the reactant and/or intermediate product 124 can come together with the fluid 126, for example, a nutrient solution, and be stored for further treatment. In a sense, the supply process unit 158 can subsequently serve as a treatment process unit 156. This can be understood, in particular, that a process unit 156, 158 can be configured in a first or a second configuration state and can be converted into the respective other configuration state.

After completion of such a conveying process, the tool elements 132, 134 are moved back into the interior 102 by means of the handling devices 128, 130.

The respective interior spaces 102, 164, 166 of the involved process units 100, 156, 158 are again closed by means of the access devices 106, 108 or door elements 110, 112 and counter access devices.

It is understood that the fluid conveying device 142 may further optionally comprise a valve device 252, which may be arranged between the first and second tool elements 132, 134.

In a sense, the fluid conveying device 142 is then formed by the fluidically interconnected tool elements 132, 134 and the valve device 252 arranged therebetween.

By means of the valve device 252, a fluid can be conveyed via the tool elements 132, 134, for example depending on the switching state of the valve device 252.

In Fig. 14, a schematic front view of a tool process unit 100 according to another exemplary embodiment of the present invention is shown. The embodiment of the tool process unit 100 shown in Fig. 14 is substantially configured and/or designed like the embodiments of the tool process unit 100 shown in Figs. 1 to 3 and/or any of the embodiments of the tool process unit 100 shown in Figs. 4 to 12, so that only the differences are described below.

As can be seen in Fig. 14, the fluid conveying device 142 is partially formed by the fluidically interconnected tool elements 132, 134.

In addition, the interior space 102 is spatially separated from one another into a first partial interior space 216 and a second partial interior space 218 and divided by means of a partition wall 220.

The partition wall 220 shields the first partial interior space 216 and the second partial interior space 218 from each other, in particular atmospherically.

The first handling device 128 with the first tool element 132 and the first access device 106 are arranged in the first partial interior space 216.

The second handling device 130 with the second tool element 134 and the second access device 108 are arranged in the second partial interior space 218.

The fluidic connection, e.g. in the form of a fluid line, between the first and the second tool element 132, 134 extends over and through the partition wall 220.

A respective air pressure prevailing in the first partial interior space 216 and the second partial interior space 218 can be varied.

A generateable air pressure difference between the first partial interior space 216 and the second partial interior space 218 serves to convey a fluid from one tool element 132, 134 to the other tool element 132, 134.

In a sense, by arranging the first tool element 132 in the first partial interior 216 and the second tool element 134 in the second partial interior 218, a pressure difference-induced conveying of a fluid from the first tool element 132 to the second tool element 134, or vice versa.

For this purpose, the tool process unit 100 comprises a device for providing the said pressure difference in the respective partial interior spaces 216, 218.

In a sense, the tool process unit 100 comprises a pressure difference device 222.

The pressure differential device 222 is assigned to the fluid delivery device 142 and, in this case, is comprised by it. This can be understood, in particular, that the fluid delivery device 142 comprises the said pressure differential device 222 and/or that the latter is assigned to the fluid delivery device 142.

If the respective access devices 106, 108 or

In order to enable a particularly aseptic transition between the counter-access devices of the coupled tool process unit 100 and further process units 156, 158, an overpressure or a negative pressure can be generated in the respective partial interior spaces 216, 218 by means of the pressure difference device 222 depending on the intended conveying direction of a fluid.

As a result, fluid can be conveyed between the treatment process unit 156 and the supply process unit 158 via the relevant components of the tool process unit 100 in a pressure difference-induced manner.

In Fig. 15, a schematic front view of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 15 is substantially configured and/or designed like the embodiments of the tool process unit 100 shown in Figs. 1 to 3 and/or any of the embodiments of the tool process unit 100 shown in Figs. 4 to 12, so that only the differences are described below.

As can be seen in Fig. 15, the tool process unit 100 comprises a single tool unit, in this case the first tool unit 120. Accordingly, the tool process unit 100 comprises a smaller number of tool units 120 than the number of access devices 106, 108, here only the first tool unit 120.

The first handling device 128 comprises a planar runner 224, on which the articulated arm 226 of the first handling device 128 is arranged and by means of which the articulated arm 226 can be moved within the interior space 102.

The planar runner 224 is arranged on the upper side 210 of the interior 102 and is movable along the upper side 210 between a region of the first access device 106 and a region of the second access device 108, and thus also the articulated arm 226. This mobility is represented schematically and exemplarily in Fig. 15 by means of a movement arrow 228. In a sense, the planar runner 224 is movable linearly.

The planar runner 224 can, for example, have a guide carriage which is, for example, rail-guided in the interior 102, in particular on the upper side 210.

Fig. 15 shows the state in which the planar runner 224 with the articulated arm 226 is arranged in the region of the first access device 106. The articulated arm 226 is extended, and the first tool element 132 is inserted into the treatment process unit 126. Additionally, an angled state of the articulated arm 226 with the first tool element 132 is shown in dashed lines.

For fluid conveyance, the articulated arm 226 with the first tool element 132 is moved successively by means of the planar rotor 224 to the respective process units 156, 158 and the first tool element 132 is introduced there accordingly, wherein a respective fluid intake and fluid discharge takes place via the syringe device 144 already described.

This can be understood, for example, to mean that the first tool unit 120 with the syringe device 144 can function as a pipette robot-like device.

In Fig. 16, a schematic front view of a tool process unit 100 according to another exemplary embodiment of the present invention is shown. The embodiment of the tool process unit 100 shown in Fig. 16 is substantially configured and/or designed like the embodiments of the tool process unit 100 shown in Figs. 1 to 3 and/or any of the embodiments of the tool process unit 100 shown in Figs. 4 to 12, so that only the differences are described below.

As can be seen in Fig. 16, the tool process unit 100 comprises a single tool unit, in this case the first tool unit 120, and a single access device, in this case the first access device 106.

For fluid delivery, the first tool element 132 is first introduced into the process unit from which fluid is to be delivered, here for example the supply process unit 158, and a corresponding fluid intake takes place via the syringe device 144 already described.

The first tool element 132 is then moved back into the interior 102 (see dashed contour) and the absorbed fluid is temporarily stored in the syringe device 144.

Subsequently, the supply process unit 158 is exchanged with the treatment process unit 156 at the first access device 106 of the tool process unit 100 (see arrow between the supply process unit 158 and the treatment process unit 156).

Such an exchange, including the associated decoupling and coupling of the relevant process units as well as the associated termination and provision of a transition between the relevant process units, can be carried out fully automatically.

Subsequently, the first tool element 132 is introduced into the process unit into which the fluid is to be dispensed, here for example the treatment process unit 156, and a corresponding fluid dispensing takes place via the syringe device 144 already described (cf. the state shown in Fig. 16).

In a sense, this involves a discontinuous conveying of fluid by means of the tool process unit 100. In Fig. 17, a schematic front view of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 17 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 16, so that only the differences are described below.

As can be seen in Fig. 17, the first tool element 132 in the present embodiment is designed as a removal element 230, in particular a sampling element, by means of which a part of an object that can be used to produce the product, e.g. a starting material and/or an intermediate product 124, or a product, in particular for sampling, can be received.

The removal element 230 is, for example, syringe-like.

In this exemplary embodiment, the first tool unit 120 also comprises an actuating actuator 232, which is arranged on the first handling device 128 and which serves to actuate the removal element 230.

By means of such actuation of the sampling element 230, a sample can be taken, preferably when the sampling element 230 is brought into contact with the object 124 to be sampled in the treatment process unit 156 by means of the first handling device 128, as shown in the illustrated state. Additionally, an angled state of the handling device 128 with the sampling element 230 is shown in dashed lines.

For further use of a taken sample, it can be released again by the sampling element 230, for example, into another process unit with corresponding sensor units in the manner already described herein for analysis of the same in the other process unit by means of the sensor units.

Additionally or alternatively, the removal element 230 can be removed from the tool process unit 100 for further use of the sample, for example analysis of the sample in other analysis systems. As can be seen in Fig. 17, the tool process unit 100 does not have a separate fluid conveying device 142. However, the removal element 230 and the actuating actuator 232 in this case assume, to a certain extent, the function of the fluid conveying device 142 and/or the syringe device 144. This can therefore be understood, for example, to mean that the removal element 230 and the actuating actuator 232 form a fluid conveying device 142.

In Fig. 18, a schematic front view of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 18 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 16, so that only the differences are described below.

As can be seen in Fig. 18, the syringe device 144 has one or more syringe elements 146.

The one or more syringe elements 146 are fluidically connectable one after the other to the first tool element 132; for example, via a suitable magazine and/or revolver device.

The one or more syringe elements 146 each serve for fluid storage.

For example, the one or more syringe elements 146 may each serve to store samples taken from the treatment process unit 156 via the first tool element 132.

For example, the one or more syringe elements 146 can each serve to store fluid, for example, treatment fluid, for example, fluid with cell growth factors, which can be delivered into the treatment process unit 156. In this case, with multiple syringe elements 146, different fluids can be stored in order to be able to carry out different treatment processes in the treatment process unit 156. In Fig. 19, a schematic front view of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 19 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 16, so that only the differences are described below.

As can be seen in Fig. 19, the tool process unit 100 has a syringe device 144 which is connected to the tool element 132 by means of a hose.

In some applications, it may be difficult to take and/or dispense small amounts and/or volumes of fluid, for example due to the length of a tubing.

The present tool process unit 100 can therefore optionally have a further pumping device 234, which can be arranged as close as possible to the tool element 132 and is arranged in the present case on the handling device 128.

For example, this further pumping device 234 is designed as a piston pump with a valve.

By means of the further pumping device 234, a fluid to be pumped can continue to be pumped, for example, regardless of whether the syringe of the syringe device 144 has already been fully retracted or extended.

In this way, even small amounts and/or volumes of fluid can be taken and/or delivered.

To a certain extent, the further pumping device 234 can function as a compensating device 234.

It is understood that the further pumping device or compensating device 234 is fluidically connected or connected to the said tubing and/or the tool element 132. This is not shown in the figure for reasons of clarity. In Fig. 20, a schematic front view of a tool process unit 100 according to another exemplary embodiment of the present invention is shown.

The embodiment of the tool process unit 100 shown in Fig. 20 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 16, so that only the differences are described below.

For descriptive purposes, the part showing differences has been shown in Fig. 20. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 20, the fluid conveying device 142 is designed as a pumping device 236, by means of which a fluid can be conveyed, in particular via a tool element 132 of the at least one tool unit 120.

In the present case, the pumping device 236 is designed, for example, as a peristaltic pump.

As in the previous embodiments, the first tool element 132 is held on the first handling device 128, which is not shown in Fig. 20 for clarity purposes.

A fluid line element 240 is coupled to the first tool element 132 via a holding contour 238.

The fluid line element 240 and the fluid line element 240 are movable together by means of the first handling device 128, in particular beyond the first access device 106 into a coupled and accessible further process unit 156, here a treatment process unit 156, for fluid intake and fluid discharge.

The tool process unit 100 further comprises a fluid treatment device 242, by means of which a fluid can be changed from a first state to a second state.

The fluid treatment device 242 is arranged upstream of the pumping device 236. In particular, the fluid treatment device 242 is arranged between the Pump device 236 and a fluid discharge opening 244 of the fluid line element 240

As can be seen in Fig. 20, the pumping device 236 is arranged between the first tool element 132 and the fluid treatment device 242.

The fluid treatment device 242 is designed here as a fluid dividing device 246, by means of which a fluid can be divided into two fluid parts.

The fluid dividing device 246 comprises a branching element 248 for dividing the fluid into the fluid parts.

The branching element 248 is fluidically connected on the inlet side to the pumping device 236 and on the outlet side to the fluid line element 240 and to a fluid intermediate storage device 250.

The fluid buffer 250 is arranged in an exchangeable manner in the interior 102 of the tool process unit 100 and is used for sampling or for receiving fluid which is to be analyzed as part of a sampling process.

In a sense, a first fluid part can be conducted into the fluid intermediate storage 250 via the branching element 248 and a second fluid part can be conducted into the fluid line element 240.

When the fluid buffer 250 is full and the pumping device 236 continues to pump fluid, the fluid can be completely directed into the fluid line element 240. In a sense, the filled fluid buffer 250 is then overflowed.

If a particularly aseptic transition between these process units 100, 156 is now enabled via the first access device 106 and the counter-access device of the coupled tool process unit 100 and treatment process unit 156, the first tool element 132 and the fluid discharge opening 244 of the fluid line element 240 can be moved out of the interior 102 of the tool process unit 100 and into the interior 164 of the treatment process unit 156 by means of the first handling device 128. There, fluidic reactant and/or intermediate product 124 is withdrawn via the first tool element 132 by means of the pumping device 236 and divided by means of the branching element 248 in order to take a sample of the reactant and/or intermediate product 124 in the fluid intermediate storage 250.

When the desired sample quantity has been taken or the fluid buffer 250 is full, the pumping device 236 stops and the fluid buffer 250 is ready for further use, e.g., analysis.

After completion of such sampling, the first tool element 132 and the fluid line element 240 are moved back into the interior space 102 by means of the first handling device 128.

The respective interior spaces 102, 164 of the involved process units 100, 156 are again closed by means of the access devices 106 or door element 110 and counter access device.

Fig. 21 shows a schematic representation of a tool process unit 100 according to another exemplary embodiment of the present invention.

The embodiment of the tool process unit 100 shown in Fig. 21 is substantially configured and/or designed like the embodiments of the tool process unit 100 shown in Figs. 1 to 3 and/or any of the embodiments of the tool process unit 100 shown in Figs. 4 to 12, so that only the differences are described below.

For descriptive purposes, a simplified, functionally oriented representation was used in Fig. 21, and the part exhibiting differences was particularly shown in Fig. 21. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 21, the fluid conveying device 142 is designed as a pumping device 236, by means of which a fluid can be conveyed.

In the present case, the pumping device 236 is designed, for example, as a peristaltic pump. If the respective access devices 106, 108 or

Counter access devices of the coupled tool process unit 100 and further process units 156, 158 enable a particularly aseptic transition between these process units 100, 156, 158 and the respective tool elements 132, 134 are positioned for fluid intake or discharge by means of the handling devices 128, 130, fluid 126 or starting material and/or intermediate product 124 can be pumped back and forth between the treatment process unit 156 and the supply process unit 158 by means of the pump device 236.

This arrangement can, for example, also be used to divide fluid, in that various further process units, here for example a plurality of supply process units 158, can be or are connected to the tool process unit 100 in the manner described herein and a corresponding fluid conveying process takes place one after the other by means of the pumping device 236.

Fig. 22 shows a schematic representation of a tool process unit 100 according to another exemplary embodiment of the present invention.

The embodiment of the tool process unit 100 shown in Fig. 22 is substantially configured and/or designed like the embodiments of the tool process unit 100 shown in Figs. 1 to 3 or Fig. 21 and/or any of the embodiments of the tool process unit 100 shown in Figs. 4 to 12, so that only the differences are described below.

For descriptive purposes, a simplified, functionally oriented representation was used in Fig. 22, and the part exhibiting differences was particularly shown in Fig. 22. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 22, the tool process unit 100 comprises a third handling device, a third tool unit with a third tool element and a third access device, which are provided in the tool process unit 100 in the manner already explained in detail herein, as explained, for example, in connection with Figs. 1 to 3.

In a sense, the tool process unit 100 can thus be connected to three further process units 156, 158 simultaneously and, in particular, can be mechanically coupled. Fig. 22 shows a state in which the tool process unit 100 is coupled to a treatment process unit 156 and two supply process units 158 and the first, second and third tool elements 132, 134 are positioned for fluid intake and fluid discharge, respectively.

As can be seen in Fig. 22, the tool process unit 100 comprises a fluid treatment device 242, by means of which a fluid can be changed from a first state to a second state, for example from an undivided state to a divided state or vice versa.

The fluid treatment device 242 is arranged downstream of the fluid conveying device 142 designed as a pumping device 236.

The fluid treatment device 242 is designed as a fluid dividing device 246, by means of which a fluid can be divided into two fluid parts.

The fluid dividing device 246 comprises a branching element 248 for dividing the fluid into a plurality of fluid parts.

In the present case, the branching element 248 is designed as a T- or Y-shaped line member for a fluid line.

The branching element 248 is fluidically connected to the first tool element 132 via the pump device 236 and is further fluidically connected to the second tool element 134 and the third tool element.

By means of the pumping device 236, fluid can be pumped from the treatment process unit 156 via the branching element 248 into the two supply process units 158.

It is understood that, in an analogous manner, respective fluid from the supply process units 158 can also be brought together via the branching element 248 and pumped into the treatment process unit 156, depending on the control of the pumping device 236. Fig. 23 shows a schematic representation of a tool process unit 100 according to another exemplary embodiment of the present invention.

The embodiment of the tool process unit 100 shown in Fig. 23 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 22, so that only the differences are described below.

For descriptive purposes, a simplified, functionally oriented representation was used in Fig. 23, and the part exhibiting differences was particularly shown in Fig. 23. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 23, the fluid treatment device 242 and in particular the fluid distribution device 246 comprises several, here two, valves 254 for selectively fluidic switching of fluid parts.

This can be understood, for example, to mean that the valves 254 can form a valve device 252.

A respective valve 254 is arranged in a respective fluid line which is located downstream of the position of the fluid distribution.

By means of the valves 254, the respective fluid parts can be controlled, in particular whether a fluid part should or will be supplied to the supply process unit 158 assigned to the respective fluid line, which is arranged on the second or the third access device 108.

Fig. 24 shows a schematic representation of a tool process unit 100 according to another exemplary embodiment of the present invention.

The embodiment of the tool process unit 100 shown in Fig. 24 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 22 and/or Fig. 23, so that only the differences are described below. For descriptive purposes, a simplified, functionally oriented representation was used in Fig. 24, and the part exhibiting differences was particularly shown in Fig. 24. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 24, the fluid treatment device 242 and in particular the fluid distribution device 246 comprises several, here two, sensor units 256 for detecting a fluid flow and/or fluid quantity relative to the respective fluid parts.

In a sense, a respective sensor unit 256 comprises a flow sensor and/or is designed as such.

A respective sensor unit 256 is arranged in and/or on a respective fluid line, which is located downstream with respect to the position of the fluid distribution and in particular of the respective valves 254.

The valves 254 and the sensor units 256 allow the fluid parts to be conveyed and/or divided to be precisely adjusted.

To a certain extent, this allows a respective fluid part to be advantageously monitored and/or fluidically controlled.

Fig. 25 shows a schematic representation of a tool process unit 100 according to another exemplary embodiment of the present invention.

The embodiment of the tool process unit 100 shown in Fig. 25 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 24, so that only the differences are described below.

For descriptive purposes, a simplified, functionally oriented representation was used in Fig. 25, and the part exhibiting differences was particularly shown in Fig. 25. The remaining parts have been omitted from the figure for clarity. The valves 254 shown in Fig. 25 are proportional valves, by means of which both discrete switching positions and a continuous transition of the valve opening can be realized.

This allows each fluid component to be fluidically controlled even more efficiently.

Furthermore, the sensor units 256 are designed as ultrasonic flow measuring sensors, which can advantageously be clamped to the respective fluid lines.

Fig. 26 shows a schematic representation of a tool process unit 100 according to another exemplary embodiment of the present invention.

The embodiment of the tool process unit 100 shown in Fig. 26 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 24 and/or Fig. 25, so that only the differences are described below.

For descriptive purposes, a simplified, functionally oriented representation was used in Fig. 26, and the part exhibiting differences was particularly shown in Fig. 26. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 26, the fluid treatment device 242 and in particular the fluid distribution device 246 comprises several, here four, valves 254 for selectively fluidic switching of fluid parts.

This can be understood, for example, to mean that the valves 254 can form a valve device 252.

Two respective valves 254 are arranged in a respective fluid line, which are located downstream of the position of the fluid distribution.

By means of the valves 254, the respective fluid parts can be controlled, in particular whether a fluid part should or will be supplied to the supply process unit 158 assigned to the respective fluid line, which is arranged on the second or the third access device 108. Furthermore, the fluid treatment device 242 and in particular the fluid distribution device 246 comprises a plurality of, here two, fluid intermediate storage devices 250 and, for each fluid intermediate storage device 250, a sensor unit 256 for detecting a state, e.g. a fill level, of the respectively assigned fluid intermediate storage device 250.

In a sense, the tool process unit 100 comprises a plurality of storage devices arranged in the interior 102, here the fluid buffers 250, for storing and/or temporarily storing fluid, by means of which a fluid can be provided for dispensing via one of the tool units and/or in which a fluid can be received via one of the tool units.

A respective sensor unit 256 can be configured, for example, as a pressure sensor. It is understood that any suitable sensor type can be used.

A respective fluid buffer 250 is arranged in a respective fluid line, which is located downstream of the position of the fluid distribution.

In particular, a respective fluid buffer 250 is fluidically arranged between two valves 254.

By means of the valves 254, a fluid supply and/or a fluid discharge can therefore be controlled with respect to the respective fluid intermediate storage 250, in particular in conjunction with the pumping device 236.

The valves 254, the sensor units 256 and the fluid buffers 250 allow the fluid parts to be conveyed and/or divided to be precisely adjusted.

By means of the fluid buffer 250, further treatment processes can also be carried out on the temporarily stored fluid, for example adding a further substance and/or fluid and/or material.

To a certain extent, the described embodiment advantageously allows a respective fluid part to be monitored and/or fluidically controlled and/or treated. Fig. 27 shows a schematic representation of a tool process unit 100 according to another exemplary embodiment of the present invention.

The embodiment of the tool process unit 100 shown in Fig. 27 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 26, so that only the differences are described below.

For descriptive purposes, a simplified, functionally oriented representation was used in Fig. 27, and the part exhibiting differences was particularly shown in Fig. 27. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 27, the fluid treatment device 242 and in particular the fluid distribution device 246 comprises several, here two, valves 254 for selectively fluidic switching of fluid parts.

The valves 254 are fluidically connected upstream of the fluid buffers 250.

Additional valves 254, which are fluidically connected downstream of the fluid buffers 250, can optionally be provided.

For each fluid buffer 250, a sensor unit 256 is provided for detecting a state, e.g., a fill level, of the respectively assigned fluid buffer 250.

A respective sensor unit 256 can, for example, be designed as a load cell, somewhat like a scale, on which a respective associated fluid buffer 250 is arranged. It is understood that any suitable sensor type can be used.

This described embodiment also allows a respective fluid part to be advantageously monitored and/or fluidically controlled and/or treated.

Fig. 28 shows a schematic representation of a tool process unit 100 according to another exemplary embodiment of the present invention. The embodiment of the tool process unit 100 shown in Fig. 28 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 23, so that only the differences are described below.

For descriptive purposes, a simplified, functionally oriented representation was used in Fig. 28, and the part exhibiting differences was particularly shown in Fig. 28. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 28, a sensor unit 256 for detecting a state, e.g. a fill level, of the container 162 is provided for each (second) container 162 in the supply process units 158.

A respective sensor unit 256 can, for example, be designed as a load cell, somewhat like a scale, on which a respective associated fluid buffer 250 is arranged. It is understood that any suitable sensor type can be used.

The sensor units 256 provided in the supply process units 158 function here as the sensor units 256 of Fig. 26 and/or Fig. 27.

It is understood that the tool process unit 100 is connected to the supply process units 158 in terms of signaling.

In the present embodiment, status values detected by the sensor units 256, e.g., fill levels of the containers 162, can be transmitted to the tool process unit 100 from the supply process units 158.

In particular, based on the transmitted values, the pumping device 236 of the tool process unit 100 can be controlled and/or operated.

This described embodiment also allows a respective fluid part to be advantageously monitored and/or fluidically controlled. 29 to 35 each show a schematic front view of a part of a tool process unit 100 according to a respective further exemplary embodiment of the present invention.

The embodiments of the tool process unit 100 shown in Figs. 29 to 35 are essentially configured and/or designed like the embodiments of the tool process unit 100 shown in Figs. 1 to 28, so that only the differences are described below.

For descriptive purposes, the part exhibiting differences, in this case the fluid treatment device 242, was shown in Figs. 29 to 35. The remaining parts have been omitted from the figures for clarity.

A respective tool process unit 100 comprises a storage device 250 arranged in the interior 102 for storing and/or temporarily storing fluid and a fluid treatment device 242 arranged in the interior 102.

For example, the storage device 250 can be formed by the fluid intermediate storage 250 already described.

By means of the storage device 250, a fluid can be provided for dispensing via at least one tool unit, e.g., the first and/or the second and/or the third tool unit 120, 122 (see arrow B) and/or a fluid can be received in the storage device 250 via at least one tool unit, e.g., the first and/or the second and/or the third tool unit 120, 122 (see arrow A).

The storage device 250 is arranged in the interior space 102 on and/or in and/or near the fluid treatment device 242.

In a sense, the storage device 250 is in operative connection with the

Fluid treatment device 242 is arranged.

As can be seen in Figs. 29 to 35, the fluid treatment device 242 is designed as a fluid mixing device 258, by means of which a fluid can be mixed and/or mixed with another component, in particular another fluid. Such a mixing or blending process takes place in the storage device 250.

To a certain extent, the storage device 250 can also be assigned to the fluid treatment device 242 and in particular to the fluid mixing device 258. To a certain extent, the fluid mixing device 258 can comprise a fluid reservoir 250, for example, the already described fluid intermediate reservoir 250, in which the fluid can be thoroughly mixed and/or mixed with another component.

Referring to Fig. 29, the fluid mixing device 258 is designed as and/or comprises a vibration and/or shaking device 260.

By means of the vibration and/or shaking device 260, the fluid can be mixed and/or mixed with another component.

The storage device or the fluid reservoir 250 can be arranged in and/or on the fluid mixing device 258 and in particular the vibration and/or shaking device 260 and is arranged here.

By means of said device 260, the storage device or the fluid storage 250 can be caused to move for mixing and/or agitation (see arrow).

For this purpose, a substrate 262 on which the storage device or the fluid reservoir 250 is arranged can be moved in different directions, e.g. two-dimensionally or three-dimensionally, by means of the said device 260, so that a content of the storage device or the fluid reservoir 250 can be mixed and/or mixed thoroughly.

In a sense, the fluid mixing device 258 has a vibrating plate-like element 264 on which the storage device or the fluid storage 250 can be arranged and/or is arranged.

Referring to Fig. 30, the fluid mixing device 258 is designed as and/or comprises a stirring device 266.

By means of the stirring device 266, the fluid can be mixed and/or mixed with another component. The stirring device 266 comprises a stirring drive 268, by means of which a stirring element 270 held or held thereon can be driven, in particular in rotation, and/or which can be coupled to a stirring element integrated in and/or on the storage device or the fluid reservoir 250 (not shown in the figure) for driving the same, in particular in rotation.

The stirring element 270 can be arranged for mixing and/or agitating in the storage device or the fluid storage 250 and is arranged here.

Referring to Fig. 31, the fluid mixing device 258 is designed as and/or comprises a resuspension device 272.

By means of the resuspension device 272, the fluid can be mixed and/or mixed with another component.

The resuspension device 272 comprises a syringe element 274, by means of which fluid can be withdrawn from the storage device or fluid reservoir 250 and released back into the storage device or fluid reservoir to achieve mixing and/or blending. It is understood that this can additionally or alternatively be done in another fluid reservoir.

For this purpose, the said device 272 comprises an actuating unit 276, for example an actuating actuator, by means of which the syringe element 274 can be pulled up and compressed again.

It is understood that the syringe device 144 described above can serve as a fluid mixing device 258 and in particular as a resuspension device 272. To a certain extent, the resuspension device 272 can be formed by the syringe device 144 described above.

Referring to Fig. 32 and Fig. 33, the fluid mixing device 258 is each designed as a magnetic stirring device 278 and/or comprises such.

By means of the magnetic stirring device 278, the fluid can be mixed and/or mixed with another component. The respective magnetic stirring device 278 comprises a stirring magnet element 280, in particular a magnetic stirring bar or stirring fish, and a magnetic drive unit 282 for magnetically driving the stirring magnet element 280.

The stirring magnet element 280 can be arranged in the storage device or the fluid storage 250 and in particular in the fluid to be mixed or mixed.

Referring to Fig. 32, the storage device or fluid reservoir 250 can be arranged on the magnetic drive unit 282.

The magnetic drive unit 282 is designed to rotate one or more drive magnets 284 below the storage device or the fluid reservoir 250 and/or to specifically control them for rotation.

As a result, the stirring magnet element 280 can be caused to rotate within the storage device or fluid reservoir 250 in order to mix and/or agitate a fluid reservoir content.

Referring to Fig. 33, the storage device or fluid reservoir 250 can be arranged on the magnetic drive unit 282.

The magnetic drive unit 282 is designed to move one or more drive magnets 284 around the storage device or the fluid reservoir 250, for example tangentially, and/or to specifically control them for such a movement.

As a result, the stirring magnet element 280 can be caused to rotate within the storage device or fluid reservoir 250 in order to mix and/or agitate a fluid reservoir content.

Referring to Fig. 34, the fluid mixing device 258 is designed as and/or comprises a pumping device 288 having a labyrinth fluid guide 286.

By means of the pumping device 288 having the labyrinth fluid guide 286, the fluid can be mixed and/or mixed with another component. To some extent, the pumping device 288 may have a labyrinth fluid guide 286 and/or may be associated with such a guide.

By means of the pumping device 288, fluid can be pumped out of the storage device or the fluid reservoir 250 via a fluid line 290 and in particular subsequently back in.

The labyrinth fluid guide 286 is provided in the fluid line 290 and in particular is integrated in the fluid line 290.

The labyrinth fluid guide 286 is designed as a meander-like fluid guide.

By allowing the components to be mixed and/or blended to pass through the labyrinth fluid guide 286, mixing and/or blending is made possible.

Referring to Fig. 35, the fluid mixing device 258 is designed as a pulse device 292 for exerting a mechanical pulse (see arrow) on the storage device or the fluid storage 250 and/or comprises such.

By means of the pulse device 292, the fluid can be mixed and/or mixed with another component.

By means of the impulse device 292, a mechanical impulse can be exerted on the storage device or the fluid reservoir 250, which can be arranged laterally with respect to the impulse device 292 and is arranged here.

To a certain extent, mixing and/or blending of the contents of the storage device or fluid reservoir 250 can be achieved by tapping sideways.

Advantageously, adherent cells, for example, can also be detached from a lateral surface of the storage device or the fluid reservoir 250 in this way.

Fig. 36 is a schematic front view of a tool process unit 100 according to another exemplary embodiment of the present invention. The embodiment of the tool process unit 100 shown in Fig. 36 is substantially configured and/or designed like the embodiments of the tool process unit 100 shown in Figs. 1 to 3 and/or any of the embodiments of the tool process unit 100 shown in Figs. 4 to 12, so that only the differences are described below.

For descriptive purposes, a simplified, functionally oriented representation was used in Fig. 36, and the part exhibiting differences was particularly shown in Fig. 36. The remaining parts have been omitted from the figure for clarity.

As can be seen in Fig. 36, the tool process unit 100 comprises a third access device 294 and a fourth access device 296, which are provided in the tool process unit 100 in the manner already detailed herein, as explained, for example, in connection with Figs. 1 to 3.

Furthermore, a third and a fourth handling device and a third and a fourth tool unit with a respective (here third or fourth) tool element are provided (not shown in the figure), which are also provided in the tool process unit 100 in the manner already explained in detail herein, as explained, for example, in connection with Figs. 1 to 3.

In a sense, the tool process unit 100 can thus be connected to four further process units 156, 158 simultaneously and, in particular, can be mechanically coupled.

Fig. 36 shows a state in which the tool process unit 100 is coupled to a treatment process unit 156 and three supply process units 158 and the first, second, third and fourth tool elements 132, 134 are positioned for fluid intake and fluid discharge, respectively.

As can be seen in Fig. 36, the tool process unit 100 comprises a fluid treatment device 242, by means of which a fluid can be changed from a first state into further states, for example, can be separated into different phases or fluid phase parts.

The fluid treatment device 242 is arranged downstream of the fluid conveying device 142 designed as a pumping device 236. The fluid treatment device 242 is designed as a fluid separation device 298, by means of which a fluid can be separated into at least two, in the present case three, components, in particular phase-dependent.

The fluid separation device 298 has a centrifuge device 300, which in this case is designed as a continuous flow centrifuge.

The centrifuge device 300 serves for the continuous or quasi-continuous separation of the fluid, here the fluidic reactant and/or intermediate product from the treatment process unit 156.

This may enable a continuous or quasi-continuous release of the individual separated components from the interior 102 via the respective access devices 108, 294, 296.

The centrifuge device 300 comprises a first sensor 302 for monitoring fluid received in the centrifuge chamber 304 before, during and/or after centrifugation (see arrow).

The first sensor 302 is arranged on and/or in the centrifuge chamber 304.

The first sensor 302 is, for example, an optical sensor, for example a color sensor.

The first sensor 302 is used to detect the phase of the fluid held in the centrifuge chamber 304 before, during and/or after centrifugation.

The centrifuge device 300 further includes a second sensor 306 for monitoring fluid discharged from the centrifuge chamber 304.

The second sensor 306 is arranged downstream of the centrifuge device 300.

In particular, the second sensor 306 is arranged between the centrifuge device 300 and the second, third and fourth access devices 108, 294, 296. The second sensor 306 is, for example, an optical sensor, for example a color sensor.

The second sensor 306 serves to detect the phase of the fluid discharged from the centrifuge chamber 304, in particular after centrifugation.

An allocation valve 308 is arranged between the second sensor 306 and the second, third and fourth access devices 108, 294, 296.

By means of the allocation valves 308, the fluid discharged from the centrifuge chamber 304 can be fluidically allocated to one or more of the access devices 108, 294, 296.

Advantageously, such an assignment can be made as a function of the phase state of the fluid detected by the second sensor 306.

To a certain extent, different and/or identical fluid phases can be supplied to the supply process units 158 depending on the switching of the allocation valves 308.

It is understood that such a process may also be possible with a smaller number of access devices by successively coupling supply process units 158 to at least one access device and successively delivering different and/or identical fluid phases there.

It is further understood that the first and/or second sensors 302, 306 can also be configured differently to detect the phases. Capacitive sensors and/or ultrasonic sensors, for example, would be conceivable.

In the state shown in Fig. 36, the pumping device 236 pumps fluid to be separated from the treatment process unit 156 in the direction of the centrifuge device 300 and in particular its centrifuge chamber 304.

The centrifuge device 300 is in operation and rotates (see arrow). In a sense, centrifugation is performed. Due to the forces occurring in the centrifuge chamber 304, the fluid introduced therein is continuously separated into its various phases (cf., for example, densely dotted area, coarsely dotted area, and white area).

This separation of the phases is monitored and detected by the first sensor 302.

Meanwhile, the densest phase (see densely dotted area) can be guided out of the centrifuge chamber 304 towards the second access device 108, the third access device 294 and the fourth access device 296.

The phase discharged from the centrifuge chamber 304 is monitored and detected by the second sensor 306.

Depending on the values detected by the second sensor 306, the phase supplied from the centrifuge chamber 304 is distributed among the supply process units 158. This is done by appropriately switching the allocation valves 308, by means of which the respectively assigned access devices 108, 294, 296 are opened and/or closed for fluid delivery.

Fig. 37 is a schematic front view of a tool process unit 100 according to another exemplary embodiment of the present invention.

The embodiment of the tool process unit 100 shown in Fig. 37 is substantially configured and/or designed like the embodiment of the tool process unit 100 shown in Fig. 36, so that only the differences are described below.

For descriptive purposes, a simplified, functionally oriented representation was used in Fig. 37, and the part exhibiting differences was particularly shown in Fig. 37. The remaining parts have been omitted from the figure for clarity.

The fluid separation device 298 has a centrifuge device 300, which is designed as a laboratory centrifuge. The centrifuge device 300 serves for the discrete separation of the fluid, here the fluidic reactant and/or intermediate product from the treatment process unit 156.

In the state illustrated in Fig. 37, the pumping device 236 pumps fluid to be separated from the treatment process unit 156 into two centrifuge containers 310 encompassed by the fluid separation device 298 (see position X). The fluid can be divided into the centrifuge containers 310, for example, via a branching element 248, as already described analogously in connection with Figs. 22 to 28.

A respective sensor unit 312, which is assigned to a respective centrifuge container 310 and is comprised by the fluid separation device 298, can be designed, for example, as a load cell, in a manner similar to a scale, on which a respectively assigned centrifuge container 310 is arranged.

By means of the sensor units 312, the amount of fluid in the containers 310 can be monitored and recorded.

Additionally or alternatively, the amount of fluid in the containers 310 can be monitored and detected by means of one or more fill level sensors 314, which can also be included in the fluid separation device 298.

After a filling process of the containers 310 by means of the pumping device 236, the containers 310 are transferred from their filling location into the centrifuge device 300 by means of a rail-guided gripper actuator 316 arranged in the interior 102 and positioned there for centrifugation (cf. position Y).

To some extent, the tool processing unit 100 can comprise a further handling device, which is designed as a rail-guided gripper actuator 316. For example, this further handling device can be part of the first tool unit 120 and/or can be assigned to it.

The centrifuge device 300 is then activated and rotates. In a sense, centrifugation is performed.

The forces occurring in the centrifuge device 300 separate the fluid in the containers 310 into its various phases. After centrifugation, the containers 310 are transferred from and to the centrifuge device 300 by means of the gripper actuator 316 to a removal location 318 and positioned there for fluid dispensing.

At the removal location 118, one or more sensors 320 are arranged to detect the phases in the containers 310. Such sensors 320 can be, for example, suitable optical sensors, e.g., color sensors, and/or suitable capacitive sensors and/or suitable ultrasonic sensors.

By means of further tool units 322 of the tool process unit 100, which are each equipped with translationally movable tool elements 324 (see arrow) and which comprise further pumping devices 326, the various phases arranged in the containers 310 can be removed in a targeted manner (see arrows emanating from tool elements 324 and position Z).

Depending on the control of the further pumping devices 326, the extracted phases can be precisely mixed via a combining member 328 arranged between the pumping devices 326 and the second to fourth access devices 108, 294, 296 and can be directed towards the second access device 108, the third access device 294 and the fourth access device 296.

Depending on the control of the additional pumping devices 326, the phase discharged from the containers 310 is distributed among the supply process units 158. This is done by appropriately switching the allocation valves 308, by means of which the respectively assigned access devices 108, 294, 296 are opened and/or closed for fluid discharge.

Fig. 38 shows a schematic front view of a portion of a tool process unit 100 according to another exemplary embodiment of the present invention.

As can be seen in Fig. 38, the fluid treatment device 242 can be designed as a fluid separation device 298 and/or can comprise one which is designed as a magnetic device 330 for phase separation. The magnetic device 330 for phase separation may be provided additionally or alternatively in any of the embodiments described in connection with Figs. 1 to 37.

In the reactant and/or intermediate product 124 to be separated, various components thereof can be specifically labeled with magnetic particles 332, e.g., magnetic particle-antibody complexes.

Subsequently, the reactant and/or intermediate product 124 thus treated is conveyed through the magnetic device 330, in which the marked and unmarked components of the reactant and/or intermediate product 124 are then magnetically separated from one another and subsequently directed into different containers.

In a sense, the magnetic device 330 may be designed as a magnetic cell separation device or magnetic activated cell sorting device, which is known to those skilled in the art.

Referring to Figs. 1 to 38, the tool process unit 100 is connectable and in particular mechanically coupled to one or more further process units 156, 158 for producing a product, in particular a biological-pharmaceutical product.

In particular, the tool process unit 100 can be connected simultaneously and, in particular, mechanically coupled to a number of further process units 156, 158 corresponding to the number of its own access devices 106, 108, 294, 296.

Such further process units 156, 158 can be designed as a treatment process unit 156, in particular for receiving and/or transporting and/or treating a reactant and/or intermediate product 124 that can be used to produce the product and/or the finished product.

Such a design of a further process unit 156, 158 as

Treatment process unit 156 corresponds to a first configuration state.

Furthermore, such further process units 156, 158 can be designed as a supply process unit 158, in particular for storing and/or temporarily storing and/or for providing an object that can be used to manufacture the product, in particular a fluid 126. Such a design of a further process unit 156, 158 as

Supply process unit 158 corresponds to a second configuration state.

As already described, the tool process unit 100 comprises one or more coupling devices by means of which this process unit 100 can be connected, in particular mechanically coupled, to one or more further process units 156, 158 and/or to a storage device and/or a transport device of a production plant.

Referring to Figs. 1 to 38, the present invention further provides a combination of multiple processing units 100, 156, 158.

Accordingly, the combination comprises the tool process unit 100 and the one or more further process units 156, 158.

It should be understood that all structural and/or functional features associated with the tool process unit 100 according to the invention and its embodiments described above and/or below can also be included in the said combination of multiple process units 100, 156, 158, either alone or in combination, and the associated properties, configurations and/or advantages can also be included and achieved accordingly.

The further process units 156, 158 are the treatment process unit 156 and/or the supply process unit(s) 158.

It is understood that the said combination may comprise several additional process units than those shown in Figs. 1 to 38.

In this case, one or more further process units can each be designed as a treatment process unit 156 and one or more further process units can each be designed as a supply process unit 158.

It is understood that all other process units can also be designed as treatment process units 156 or supply process units 158. Referring to Figs. 1 to 38 and the explanations regarding said combination, the present invention also provides a process unit for producing a product, in particular a biological-pharmaceutical product, which, with reference to Figs. 1 to 38, is the treatment process unit 156 and/or the supply process unit 158.

As already described, this process unit 156, 158 comprises: an interior space 164, 166 formed by a wall 168, 170, in particular for receiving and/or transporting and/or treating an object; and at least one access device or counter-access device for enabling access to the interior space 164, 166.

The said process unit 156, 158 can be coupled to a tool process unit 100 for producing a product, in particular a biological-pharmaceutical product.

The tool process unit 100 is able to access the interior 164, 166 via the at least one access device or counter-access device in the coupled state.

The process unit 156, 158 is configured in one or the first or in one or the second configuration state and can be transferred into the respective other configuration state.

In a sense, the process unit 156, 158 is designed as a treatment process unit 156 in the first configuration state.

In a sense, the process unit 156, 158 is designed as a supply process unit 158 in the second configuration state.

For example, if reactant and/or intermediate product 124 is supplied from a treatment process unit 156 via the tool process unit 100 to a supply process unit 158, for example, is added to a fluid 126 arranged there, a configuration change of the supply process unit 158 can take place from the second configuration state to the first configuration state. The supply process unit 158 and now treatment process unit 156 then serves to receive and/or transport and/or treat a reactant and/or intermediate product 124 that can be used to manufacture the product and/or the finished product.

For example, if a reactant and/or intermediate product 124 is treated in a treatment process unit 156 such that it functions as an object 124, 126, in particular fluid 126, that can be used to produce the product, for example after adding another fluid with cell growth agents, a configuration change of the treatment process unit 156 can take place from the first configuration state to the second configuration state.

Furthermore, it should be understood that, although Figs. 1 to 38 have been described in connection with tool units 120, 122, additionally or alternatively, sensor units for analyzing an object 124, 126 usable for manufacturing the product may be provided.

A respective sensor unit can comprise at least one handling device 128, 130 and a sensor element held on the at least one handling device 128, 130, which can be moved by means of the at least one handling device 128, 130 within the interior 102 and, when access is enabled, out of the interior 102 via the at least one access device 106, 108, 294, 296.

It is understood that the handling device 128, 130 of the sensor unit can be designed like the handling device 128, 130 of the tool unit 120, 122 described herein.

For example, it can be provided that a sensor unit is designed to determine one or more values of one or more parameters of a reactant and/or intermediate product 124, 126 that can be used to produce the product and/or of the finished product.

For example, it can be provided that a sensor unit for determining a treatment progress during the treatment of a starting material and/or intermediate product 124 that can be used to produce the product and/or the finished product and/or is designed to determine the treatment progress of said objects between two treatment processes.

Based on Fig. 16, an embodiment with a sensor unit 120 will be described below as an example.

Starting from Fig. 16, the tool process unit 100 comprises a sensor unit 120 for analyzing an object 124, 126 that can be used to manufacture the product.

The sensor unit 120 comprises the handling device 128 and a sensor element 132 held on the handling device 128, which can be moved by means of the handling device 128 within the interior space 102 and, when access is enabled via the access device 106, out of the interior space 102.

By means of the syringe device 144, fluid from the treatment process unit 156 can be absorbed into the sensor element 132.

Within the sensor element 132, sensors are configured to determine one or more values of one or more parameters of the absorbed fluid. An analysis can now be performed.

After analysis, the absorbed fluid can be released again and/or stored in the syringe element 146 of Fig. 16 for further use.

It is further understood that additionally or alternatively it can be provided that the at least one sensor unit and the at least one tool unit 120, 122 have a common handling device by means of which a sensor element of the at least one sensor unit and/or a tool element 132, 134 of the at least one tool unit 120, 122 can be moved within the interior 102 and out of the interior when access is enabled via the at least one access device 106, 108, 294, 296.

It is understood that the common handling device can be designed like the handling device 128, 130 of the tool unit 120, 122 described herein. It is further understood that the tool process unit 100 comprises a control device and/or is assigned such a control device.

As already described, this can be arranged, for example, in the technology box 140.

By means of this control device, the operation of the tool process unit 100 can be controlled.

For example, all components, for example fluidic components, mechanical components, electronic components, etc., of the tool process unit 100 can be controlled by means of this control device.

It is further understood that the further process units 156, 158 each comprise a control device and/or are respectively assigned such a control device.

By means of this control device, the operation of the further process units 156, 158 can be controlled.

For example, all components, for example fluidic components, mechanical components, electronic components, etc., of the further process units 156, 158 can be controlled by means of this control device.

It is further understood that the tool process unit 100 and the further process units 156, 158 each comprise energy storage devices, in particular for power supply.

List of reference symbols

Tool process unit

Interior

Wall first access device second access device first door element second door element first access opening second access opening

Bottom first tool unit second tool unit first object second object first handling device second handling device first tool element second tool element

Clamping device

Rear side additional interior; technology box

Fluid conveying device

Syringe device

syringe element

valve

Actuating actuators

swivel arm

Holder additional process unit; treatment process unit additional process unit; supply process unit first container second container

Interior of treatment process unit

Interior of supply process unit Wall of treatment process unit

Wall of supply process unit Insulation element first partial wall second partial wall further insulation element

T emperator

Cooling container

Temperature control unit

Heat sink first thermal interior second thermal interior thermal partition

Air circulation unit first passage line second passage line

Fluid supply unit

Fluid discharge unit

Cooling unit

Coupling device

Fluid line unit

Top

Inlet opening

Outlet opening first partial interior second partial interior

Partition wall

Pressure difference device

Planar runner

Articulated arm

Movement arrow

Removal element

Actuating actuators

Compensation device

Pumping device

Holding contour Fluid line element

Fluid treatment facility

Fluid discharge opening of fluid line element

Fluid distribution device

branch element

Fluid buffer; storage device; fluid storage

Valve device

Valve of fluid treatment device

Sensor unit of fluid treatment device

Fluid mixing device

Vibration and/or shaking device

Underground

Vibrating plate-like element

Stirring device

Stirring drive

stirring element

Resuspension device

syringe element

Actuating unit

Magnetic stirring device

Stirring magnet element

Magnetic drive unit

drive magnet

Labyrinth fluid guide

Pumping device

Fluid line

Impulse device third access device fourth access device

Fluid separation device

Centrifuge device first sensor

Centrifuge chamber second sensor

Allocation valve

Centrifuge container 312 Sensor unit

314 Level sensor

316 Gripper actuators

318 withdrawal point

320 sensors

322 additional tool units

324 additional tool element

326 additional pumping equipment

328 merging link

330 Magnetic device for phase separation

332 magnetic particles

A schematic fluid intake

B schematic fluid delivery

G Direction of gravity

X Position

Y Position

Position

Claims

Patent claims 1. A tool process unit (100) for producing a product, in particular a biological-pharmaceutical product, comprising: an interior space (102) formed by a wall (104); at least one access device (106, 108) for enabling access to the interior space (102); and at least one tool unit (120, 122), in particular for treating an object (124, 126) that can be used to manufacture the product, wherein the at least one tool unit (120, 122) is arranged in the interior space (102), and/or at least one sensor unit (120), in particular for analyzing an object (124, 126) that can be used to manufacture the product, wherein the at least one sensor unit (120) is arranged in the interior space (102), wherein the at least one tool unit (120, 122) and/or the at least one sensor unit (120) is movable within the interior space (102) and, when access is enabled via the at least one access device (106, 108), is movable at least partially out of the interior space (102). 2. Tool processing unit (100) according to claim 1, characterized in that the tool processing unit (100) comprises a plurality of access devices (106, 108) for respectively enabling access to the interior (102), wherein the at least one tool unit (120, 122) and/or the at least one sensor unit (120) can be moved at least partially out of the interior (102) via each of the access devices (106, 108) when access is respectively enabled. 3. Tool processing unit (100) according to one of the preceding claims, characterized in that the tool processing unit (100) comprises a number, in particular a total number, of tool units (120, 122) and/or sensor units (120) corresponding to the number of access devices (106, 108) or a smaller or larger number, wherein preferably a respective tool unit (120, 122) and/or a respective sensor unit (120) is each assigned to one or more access devices (106, 108) in order to be movable at least partially out of the interior (102) in particular via this access device (106, 108) or access devices (106, 108). 4. Tool processing unit (100) according to one of the preceding claims, characterized in that by means of a respective access device (106, 108) a respective access is made possible, which is oriented along a height direction, in particular the direction of gravity (G), or a direction running transversely thereto of the tool processing unit (100), wherein in particular two or more access devices (106, 108) are provided, which are arranged on a same side, preferably top side (210) or bottom side (118), of the tool processing unit (100) and/or on opposite sides, preferably top side (210) and bottom side (118), of the tool processing unit (100). 5. Tool process unit (100) according to one of the preceding claims, characterized in that the at least one tool unit (120, 122) has at least one Handling device (128, 130) and a at least one Handling device (128, 130) held tool element (132, 134) which can be moved by means of the at least one handling device (128, 130) within the interior space (102) and, when access is enabled, out of the interior space (102) via the at least one access device (106, 108). 6. Tool process unit (100) according to one of the preceding claims, characterized in that the at least one tool unit (120, 122) comprises a fluid conveying device (142) by means of which a fluid (126) can be conveyed and/or caused to be conveyed, in particular via a tool element (132, 134) of the at least one tool unit (120, 122). 7. Tool process unit (100) according to claim 6, characterized in that at least one of the following applies: the fluid conveying device (142) is designed as a pumping device (236) and/or comprises such a device, by means of which a fluid can be conveyed, in particular via a tool element (132, 134) of the at least one tool unit (120, 122); and/or the fluid conveying device (142) is designed as a syringe device (144) and/or comprises one by means of which a fluid (126) can be conveyed, in particular via a tool element (132, 134) of the at least one tool unit (120, 122); and/or the fluid conveying device (142) is designed as a valve device (252) and/or comprises one by means of which a fluid can be conveyed, in particular via a tool element (132, 134) of the at least one tool unit (120, 122). 8. Tool process unit (100) according to claim 6 or 7, characterized in that the fluid conveying device (142) has: a first tool element (132) for fluid intake, into which a fluid for conveying can flow, and a second tool element (134) for fluid discharge, from which a fluid can flow out again and which is directly or indirectly fluidically connected to the first tool element (132), wherein at least one of the following applies: an inflow opening (212) of the first tool element (132) is arranged or can be arranged higher with respect to the direction of gravity (G) than an outflow opening (214) of the second tool element (134); and/or the interior space (102) is spatially separated and divided from one another by means of a partition wall (220) into a first partial interior space (216) and a second partial interior space (218), wherein an air pressure prevailing in the first partial interior space (216) and the second partial interior space (218) differs from one another and the first tool element (132) is arranged in the first partial interior space (216) and the second tool element (134) is arranged in the second partial interior space (218) for the pressure difference-induced conveyance of a fluid from the first tool element (132) to the second tool element (134); and/or a pump device (236) is fluidically arranged between the first tool element (132) and the second tool element (134); and/or a syringe device (144) is fluidically arranged between the first tool element (132) and the second tool element (134); and/or a valve device (252) is fluidly arranged between the first tool element (132) and the second tool element (134). 9. Tool process unit (100) according to one of the preceding claims, characterized in that the at least one tool unit (120, 122) comprises a fluid treatment device (242) by means of which a fluid can be changed from a first state to a second state, wherein at least one of the following applies: the fluid treatment device (242) is designed as a fluid dividing device (246) and/or comprises such a device by means of which a fluid can be divided into at least two fluid parts, in particular sequentially and/or continuously, wherein optionally the fluid dividing device (246) comprises one or more valves (254) and/or one or more sensor units (256) for detecting a fluid flow and/or fluid quantity and/or one or more fluid buffers (250); and/or the fluid treatment device (242) is designed as a fluid mixing device (258) and/or fluid mixing device and/or comprises one by means of which a fluid can be mixed and/or mixed with a further component, in particular a further fluid; and/or the fluid treatment device (242) is designed as a fluid separation device (298) and/or comprises one by means of which a fluid can be separated into at least two components, in particular phase-dependently, wherein optionally the fluid separation device (298) has at least one of the following: a centrifuge device (300), a magnetic device (330), a filter device, a membrane device, a countercurrent device and/or a column device. 10. Tool processing unit (100) according to one of the preceding claims, characterized in that the at least one sensor unit (120) comprises at least one handling device (128) and a sensor element (132) held on the at least one handling device (128), which can be moved by means of the at least one handling device (128) within the interior space (102) and, when access is enabled, out of the interior space (102) via the at least one access device (106); and/or the at least one sensor unit (120) and the at least one tool unit (120, 122) have a common handling device (128), by means of which a sensor element (132) of the at least one sensor unit (120) and/or a tool element (132, 134) of the at least one tool unit (120, 122) within the interior space (102) and, when access is enabled, can be moved out of the interior space (102) via the at least one access device (106, 108). 11. Tool processing unit (100) according to one of the preceding claims, characterized in that the tool processing unit (250) comprises a storage device (250, 310) arranged in the interior (102) for storing and/or temporarily storing fluid, by means of which a fluid can be provided for dispensing via the at least one tool unit (120, 122) and/or in which a fluid can be received via the at least one tool unit (120, 122), wherein in particular the storage device (250, 310) comprises a disposable container, in particular a bag-like disposable container, and/or such a container can be fluidically and/or mechanically coupled to the storage device (250, 310). 12. Tool process unit (100) according to one of the preceding claims, characterized in that the tool process unit (100) can be connected and in particular mechanically coupled to one or more further process units (156, 158) for producing a product, in particular a biological pharmaceutical product, wherein in particular the tool process unit (100) can be connected and in particular mechanically coupled to a number of further process units (156, 158) corresponding to the number of its own access devices (106, 108) at the same time, wherein preferably a respective further process unit (156, 158) is designed as a treatment process unit (156), in particular for receiving and/or transporting and/or treating a reactant and/or intermediate product (124) and/or the finished product that can be used for producing the product, and/or as a supply process unit (158), in particular for storing and/or temporarily storing and/or providing a of the product usable object (124, 126), in particular a fluid (126). 13. Combination of several process units (100, 156, 158), comprising: at least one tool process unit (100) for producing a product, in particular a biological-pharmaceutical product, according to one of the preceding claims, and one or more further process units (156, 158) for producing a product, in particular a biological-pharmaceutical product, wherein the at least one tool process unit (100) and the one or more further process units (156, 158) can be connected to one another and in particular can be mechanically coupled, wherein preferably the at least one tool unit (120, 122) and/or the at least one sensor unit (120) of the at least one tool process unit (100) can be moved at least partially out of the interior space (102) of the at least one tool process unit (100) and into the respective further process unit (156, 158) in the coupled state and when access is enabled. 14. Process unit (156, 158) for producing a product, in particular a biological-pharmaceutical product, comprising: an interior space formed by a wall (168, 170), in particular for receiving and/or transporting and/or treating an object (124, 126); and at least one access device for enabling access to the interior (164, 166), wherein the process unit (156, 158) can be coupled to a tool process unit (100) for producing a product, in particular a biological-pharmaceutical product, which tool process unit (100) can be given access to the interior (164, 166) via the at least one access device in the coupled state, wherein the process unit (156, 158) is designed in a first or in a second configuration state and can be transferred into the respective other configuration state. 15. Process unit (156, 158) according to claim 14, characterized in that the process unit (156, 158) in the first configuration state is designed as a treatment process unit (156) for receiving and/or transporting and/or treating a reactant and/or intermediate product (124) that can be used to produce the product and/or the finished product, and wherein the process unit (156, 158) in the second configuration state is designed as Supply process unit (158) for storing and/or buffering and/or is designed to provide an object (124, 126), in particular a fluid (126), that can be used to manufacture the product.