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WO2025097289A1 - Composition pour le soin des matières kératiniques - Google Patents

Composition pour le soin des matières kératiniques Download PDF

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Publication number
WO2025097289A1
WO2025097289A1 PCT/CN2023/130075 CN2023130075W WO2025097289A1 WO 2025097289 A1 WO2025097289 A1 WO 2025097289A1 CN 2023130075 W CN2023130075 W CN 2023130075W WO 2025097289 A1 WO2025097289 A1 WO 2025097289A1
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WO
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Prior art keywords
acid
radical
composition
mixtures
alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/CN2023/130075
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English (en)
Inventor
Yu Liu
Qingsheng Tao
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LOreal SA
Original Assignee
LOreal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by LOreal SA filed Critical LOreal SA
Priority to PCT/CN2023/130075 priority Critical patent/WO2025097289A1/fr
Priority to FR2313895A priority patent/FR3154920A3/fr
Publication of WO2025097289A1 publication Critical patent/WO2025097289A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0295—Liquid crystals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/39—Derivatives containing from 2 to 10 oxyalkylene groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Definitions

  • the present invention relates to a cosmetic composition.
  • the present invention relates to a composition for caring for keratin materials.
  • the present invention also relates to a non-therapeutic method for caring for keratin materials.
  • Skin acts as a natural barrier between internal and external environments and therefore plays an important role in vital biological functions such as protection against mechanical and chemical injury, micro-organisms, and ultraviolet damage.
  • Ceramides are the main natural lipids in the stratum corneum, accounting for 50%of total intercellular lipids. When the concentration of ceramides is insufficient, the skin tends to become dry and sensitive. Topical application of ceramides can restore the skin barrier and retain moisture. However, ceramides have high crystallinity and easily to form molecular crystals. Ceramides can be dispersed into water using a surfactant or the like, but it is difficult to sufficiently reduce the particle size thereof (i.e., to obtain higher transparency) , and high dosage of surfactant is required.
  • SLNs solid lipid nanoparticles
  • SLN solid lipid nanoparticles
  • SLNs solid lipid nanoparticles
  • SLN are normally spherical with the diameter of smaller than 500 nm (more preferably ⁇ 100 nm) .
  • the structure of SLNs is a hydrophobic solid lipid core surrounded by a surfactant layer.
  • the intrinsic properties of SLNs are deeper skin penetration, low toxicity, and high bioavailability.
  • compositions containing solid lipid nanoparticles are emerging in the field of cosmetics and dermatology, especially for the encapsulation of hydrophobic cosmetic active ingredients into the lipid core.
  • Some cosmetic actives such as ceramides are insoluble in water. Dissolving them directly into an oil may bring about greasy feeling. Thanks to SLNs, they can be readily introduced into water-based formulae, thereby obtaining homogeneous suspensions.
  • the typical methods for preparing SLNs include high-speed and high-pressure homogenization, high-frequency sonication, membrane emulsification, which requires high mechanical energy input, high cost and difficult to achieved from the industrial level.
  • One object of the present application is to provide solid lipid nanoparticles comprising ceramides, which can be easily prepared.
  • Another object of the present application is to provide a formulation for preparing solid lipid nanoparticles comprising ceramides, which can be easily processed into solid lipid nanoparticles.
  • the present invention provides a composition, preferably for caring for keratin materials, comprising:
  • the composition is a homogeneous mixture. Solid lipid nanoparticles can be easily formed from the homogeneous mixture.
  • the composition is in the form of solid lipid nanoparticles.
  • the solid lipid nanoparticles can be easily formed.
  • the composition is in the form of suspension of solid lipid nanoparticles in an aqueous phase.
  • the suspension of the present invention can be used for caring for the skin.
  • the present invention provides a non-therapeutic method for caring for keratin materials, comprising applying the composition according to the first aspect of the present invention to the keratin materials.
  • keratin materials is intended to cover human skin, mucous membranes such as the lips, and the hair. Facial skin is most particularly considered according to the present invention.
  • composition according to the present invention comprises:
  • the composition of the present invention comprises at least one compound of ceramide type.
  • the term “compound of ceramide type” is understood to mean natural and/or synthetic ceramides and/or glycoceramides and/or pseudoceramides and/or neoceramides.
  • the compounds of ceramide type which can be used according to the present invention preferably correspond to the general formula (I) :
  • R denotes hydrogen or a mono-or polyhydroxylated, preferably monohydroxylated, C 1 -C 20 hydrocarbon radical, R’ and R” are each independently hydrocarbon radicals, the sum of the carbon atoms of which is between 9 and 30, R’ being a divalent radical;
  • R 8 denotes a C 1 -C 20 hydrocarbon radical and p is an integer varying from 1 to 12;
  • -R 2 is chosen from hydrogen, a radical of saccharide type, in particular a (glycosyl) n , (galactosyl) m or sulphogalactosyl radical, a sulphate or phosphate residue, a phosphorylethylamine radical and a phosphorylethylammonium radical, in which n is an integer varying from 1 to 4 and m is an integer varying from 1 to 8;
  • R 3 denotes hydrogen or a hydroxylated or nonhydroxylated and saturated or unsaturated C 1 -C 33 hydrocarbon radical, optionally the hydroxyl or hydroxyls being esterified by an inorganic acid or an acid R 7 COOH, R 7 having the same meanings as hereinabove, and optionally the hydroxyl or hydroxyls being etherified by a (glycosyl) n , (galactosyl) m , sulphogalactosyl, phosphorylethylamine or phosphorylethylammonium radical, n and m having the same meanings as hereinabove, optionally R 3 being substituted by one or more C 1 -C 14 alkyl radicals; preferably, R 3 denotes a C 15 -C 26 ⁇ -hydroxyalkyl radical, the hydroxyl group optionally being esterified by a C 16 -C 30 ⁇ -hydroxy acid;
  • R 4 denotes hydrogen, a methyl or ethyl radical, an optionally hydroxylated, saturated or unsaturated and linear or branched C 3 -C 50 hydrocarbon radical or a-CH 2 -CHOH-CH 2 -O-R 6 radical, in which R 6 denotes a C 10 -C 26 hydrocarbon radical, or an R 8 -O-CO- (CH 2 ) p radical, in which R 8 denotes a C 1 -C 20 hydrocarbon radical and p is an integer varying from 1 to 12;
  • -R 5 denotes hydrogen or an optionally mono-or polyhydroxylated, saturated or unsaturated and linear or branched C 1 -C 30 hydrocarbon radical, optionally the hydroxyl or hydroxyls being etherified by a (glycosyl) n , (galactosyl) m , sulphogalactosyl, phosphorylethylamine or phosphorylethylammonium radical, in which n is an integer varying from 1 to 4 and m is an integer varying from 1 to 8;
  • R 3 and R 5 denote hydrogen or when R 3 denotes hydrogen and R 5 denotes methyl, then R 4 does not denote hydrogen or a methyl or ethyl radical.
  • the compounds of ceramide type which are more particularly preferred according to the invention are the compounds of formula (I) for which R 1 denotes an optionally hydroxylated and saturated or unsaturated alkyl derived from C 14 -C 22 fatty acids; R 3 denotes an optionally hydroxylated and linear C 11 -C 17 radical and preferably C 13 -C 15 radical, preferably denotes an ⁇ -hydroxycetyl radical, and R 2 , R 4 and R 5 denote hydrogen.
  • R 1 denotes an optionally hydroxylated and saturated or unsaturated alkyl derived from C 14 -C 22 fatty acids
  • R 3 denotes an optionally hydroxylated and linear C 11 -C 17 radical and preferably C 13 -C 15 radical, preferably denotes an ⁇ -hydroxycetyl radical
  • R 2 , R 4 and R 5 denote hydrogen.
  • the compound of ceramide type is selected from 2-N-linoleoylamino-octadecane-1, 3-diol; 2-N-oleoylamino-octadecane-1, 3-diol; 2-N-palmitoylamino-octadecane-1, 3-diol; 2-N-stearoylamino-octadecane-1, 3-diol; 2-N-behenoylamino-octadecane-1, 3-diol; 2-N- [2-hydroxy-palmitoyl] -amino-octadecane-1, 3-diol; 2-N-stearoyl amino-octadecane-1, 3, 4-triol and in particular N-stearoyl phytosphingosine, 2-N-palmitoylamino-hexadecane-1, 3-diol, N-linoleoyldihydro
  • the ceramide may be selected from N-alpha-hydroxystearoyl-phytosphingosine (also called ceramide AP) , sold, for example, as DS-CERAMIDE AP by Solus Advanced Materials, N-stearoyl phytosphingosine (also called ceramide NP) , sold, for example, as DS-CERAMIDE Y3S by Solus Advanced Materials Co., Ltd., and mixtures thereof.
  • N-alpha-hydroxystearoyl-phytosphingosine also called ceramide AP
  • DS-CERAMIDE AP N-alpha-hydroxystearoyl-phytosphingosine
  • ceramide NP N-stearoyl phytosphingosine
  • the compound of ceramide type is present in the composition of the present invention in an amount ranging from 0.01 wt. %to 0.5 wt. %, preferably from 0.02 wt. %to 0.3 wt. %, more preferably from 0.05 wt. %to 0.25 wt. %, relative to the total weight of the composition.
  • the composition of the present invention comprises at least one solid lipid other than compounds of ceramide type.
  • solid lipid means that the lipid is solid at room temperature (25°C) and atmospheric pressure (1.013 X10 5 Pa) .
  • the melting point is above 25°C, preferably above 45°C.
  • Solid lipid other than compounds of ceramide type can be selected from solid fatty acids, solid fatty alcohols, waxes, mono-, di-or triglycerides, and mixtures thereof.
  • the solid fatty acids comprise 12-24 carbons with one carboxyl group, preferably the solid fatty acid is selected from lauric acid, myristic acid, palmitic acid, stearic acid, arachidic acid, behenic acid, lignoceric acid and mixtures thereof, more preferably the solid fatty acid is selected from myristic acid, palmitic acid, stearic acid, and mixtures thereof.
  • the solid fatty alcohols comprise 12-24 carbons with one hydroxyl group
  • the solid fatty alcohol is selected from cetyl alcohol, stearyl alcohol, cetearyl alcohol, myristyl alcohol, lauryl alcohol, tridecyl alcohol, pentadecyl alcohol, hexadecyl alcohol, arachidyl alcohol, behenyl alcohol, and mixtures thereof, more preferably the solid fatty alcohol is selected from cetyl alcohol, stearyl alcohol, cetearyl alcohol, and mixtures thereof.
  • the waxes are waxes of animal, vegetable, mineral origin, non-silicone synthetic waxes and mixtures thereof, preferably the wax is selected from hydrocarbon waxes, such as beeswax, lanolin wax, and Chinese insect waxes; rice bran wax, Carnauba wax, Candellila wax, Ouricury wax, Alfa wax, Berry wax, Shellac wax, Japanese wax and sumac wax; Montan wax, orange and lemon waxes, microcrystalline waxes, paraffins and ozokerite, and mixtures thereof.
  • hydrocarbon waxes such as beeswax, lanolin wax, and Chinese insect waxes
  • rice bran wax Carnauba wax, Candellila wax, Ouricury wax, Alfa wax, Berry wax, Shellac wax, Japanese wax and sumac wax
  • Montan wax orange and lemon waxes, microcrystalline waxes, paraffins and ozokerite, and mixtures thereof.
  • the mono-, di-or triglycerides is selected from esters of saturated or unsaturated, linear, or branched fatty acid including 10 to 22 carbon atoms, preferably, the mono-, di-or triglyceride is selected from mono-, di-or triglycerides of one or more of lauric acid, oleic acid, stearic acid, isostearic acid, capric acid, caprylic acid, and myristic acid.
  • the solid lipid other than compounds of ceramide type is selected from candelilla wax, beeswax, shea butter, glyceryl mono-/di-/tri-stearate, and mixtures thereof.
  • the solid lipid other than compounds of ceramide type is present in the composition of the present invention in an amount ranging from 1 wt. %to 20 wt. %, preferably from 2 wt. %to 15 wt. %, more preferably from 3 wt. %to 10 wt. %, relative to the total weight of the composition.
  • the weight ratio of the solid lipid other than compounds of ceramide type to the compound of ceramide type is from 20 to 5000, preferably from 20 to 3000, more preferably from 20 to 2000, even more preferably from 20 to 1000, most preferably from 30 to 500.
  • Double-chain non-ionic surfactants are Double-chain non-ionic surfactants
  • composition of the present invention comprises at least one double-chain non-ionic surfactant.
  • the double-chain non-ionic surfactant is different from solid lipids mentioned above.
  • the double-chain non-ionic surfactant is selected from diesters of one or more saturated or unsaturated, linear or branched fatty acids including 8 to 22, preferably 10 to 18 carbon atoms and polyglycerin with a polyglyceryl moiety derived from 2 to 10 glycerol units.
  • saturated or unsaturated, linear or branched fatty acids including 8 to 22 carbon atoms
  • the double-chain non-ionic surfactant is selected from PG2 dicaprate, PG2 dicaprylate, PG2 dilaurate, PG2 dimyristate, PG2 distearate, PG2 diisostearate, PG2 dioleate, PG3 dicaprate, PG3 dicaprylate, PG3 dilaurate, PG3 dimyristate, PG3 distearate, PG3 diisostearate, PG3 dioleate, PG4 dicaprate, PG4 dicaprylate, PG4 dilaurate, PG4 dimyristate, PG4 distearate, PG4 diisostearate, PG4 dioleate, PG5 dicaprate, PG5 dicaprylate, PG5 dilaurate, PG5 dimyristate, PG5 distearate, PG5 diisostearate, PG5 dioleate, PG6 dicap
  • the double-chain non-ionic surfactant is selected from polyglyceryl dioleate, polyglyceryl distearate, and mixtures thereof.
  • the double-chain non-ionic surfactant can be derived from renewable source.
  • the double-chain non-ionic surfactant is present in the composition of the present invention in an amount ranging from 0.1 wt. %to 10 wt. %, preferably from 0.5 wt. %to 8 wt. %, more preferably from 1 wt. %to 6 wt. %, relative to the total weight of the composition.
  • composition of the present invention comprises at least one single-chain non-ionic surfactant.
  • the single-chain non-ionic surfactant is different from solid lipids mentioned above.
  • the single-chain non-ionic surfactant is selected from monoesters of one or more saturated or unsaturated, linear or branched fatty acids including 8 to 22, preferably 10 to 18 carbon atoms and polyglycerin with a polyglyceryl moiety derived from 2 to 10 glycerol units.
  • the single-chain non-ionic surfactant is selected from PG2 caprate, PG2 caprylate, PG2 laurate, PG2 myristate, PG2 stearate, PG2 isostearate, PG2 oleate, PG3 caprate, PG3 caprylate, PG3 laurate, PG3 myristate, PG3 stearate, PG3 isostearate, PG3 oleate, PG4 caprate, PG4 caprylate, PG4 laurate, PG4 myristate, PG4 stearate, PG4 isostearate, PG4 oleate, PG5 caprate, PG5 caprylate, PG5 laurate, PG5 myristate, PG5 stearate, PG5 isostearate, PG5 oleate, PG6 caprate, PG6 caprylate, PG6 laurate, PG6 myristate, PG6 my
  • the single-chain non-ionic surfactant can be derived from renewable source.
  • the single-chain non-ionic surfactant is selected from polyglyceryl laurate, polyglyceryl myristate, polyglyceryl stearate, and mixtures thereof.
  • the single-chain non-ionic surfactant is present in the composition of the present invention in an amount ranging from 0.1 wt. %to 10 wt. %, preferably from 0.5 wt. %to 8 wt. %, more preferably from 1 wt. %to 6 wt. %, relative to the total weight of the composition.
  • the ratio of the total weight of the double-chain nonionic surfactant and the single-chain nonionic surfactant to the weight of the solid lipid is from 0.2 to 20, preferably from 0.3 to 15, more preferably from 0.4 to 10, most preferably from 0.5 to 5.
  • composition of the present invention may comprise a continuous aqueous phase.
  • Said aqueous phase comprises water.
  • said aqueous phase is present in an amount ranging from 20 wt. %to 99 wt. %, preferably from 30 wt. %to 99 wt. %, and more preferably from 50 wt. %to 99 wt. %of the total weight of the composition.
  • composition of the present invention may comprise an additional cosmetic active ingredient in addition to the compound of ceramide type.
  • cosmetic active ingredient examples include natural extracts; vitamins such as vitamin A (retinol) , vitamin E (tocopherol) , vitamin C (ascorbic acid) , vitamin B5 (panthenol) , vitamin B3 (niacinamide) , and derivatives of said vitamins (in particular esters) and mixtures thereof; urea; caffeine; salicylic acid and derivatives thereof; alpha-hydroxy acids such as lactic acid or glycolic acid and derivatives thereof; sunscreens; extracts from algae, fungi, plants, yeasts and bacteria; enzymes; agents acting on the microcirculation, and so on.
  • vitamins such as vitamin A (retinol) , vitamin E (tocopherol) , vitamin C (ascorbic acid) , vitamin B5 (panthenol) , vitamin B3 (niacinamide)
  • urea caffeine
  • salicylic acid and derivatives thereof alpha-hydroxy acids
  • sunscreens extracts from algae, fungi, plants, yeasts and bacteria
  • enzymes
  • composition of the present invention may also contain conventional cosmetic adjuvants or additives, for instance fragrances, chelating agents, preserving agents and bactericides, thickeners, pH regulators, fillers and mixtures thereof.
  • fragrances for instance fragrances, chelating agents, preserving agents and bactericides, thickeners, pH regulators, fillers and mixtures thereof.
  • preserving agents and bactericides for instance fragrances, chelating agents, preserving agents and bactericides, thickeners, pH regulators, fillers and mixtures thereof.
  • the present invention provides a composition for caring for keratin materials comprising, relative to the total weight of the composition:
  • the composition is a homogeneous mixture, from which solid lipid nanoparticles can be easily formed by spontaneous emulsification without involving vigorous mechanical energy input, for example high-speed and high-pressure homogenization, sonication, or membrane emulsification.
  • the composition is in the form of solid lipid nanoparticles.
  • the solid lipid nanoparticles can be easily formed and the macroscopic crystallization of compounds of ceramide type can be effectively suppressed.
  • the composition is in the form of suspension of solid lipid nanoparticles in an aqueous phase.
  • the suspension can be easily formed and the macroscopic crystallization of compounds of ceramide type can be effectively suppressed.
  • the composition of the present invention is in the form of a translucent or semi-translucent suspension of solid lipid nanoparticles in aqueous phase.
  • the composition When the particle size of nanoparticle is from 110 to 150 nm, then the composition is considered semi-translucent; and when the particle size of nanoparticle is less than 110 nm, then the composition is considered translucent. When the particle size of nanoparticle is greater than 500 nm., then the composition is considered creamy.
  • composition of the present invention can be in the form of lotion, cream, serum, etc.
  • composition of the present invention can be used as shampoos, hair coloring products, and hair conditions, skincare products, etc.
  • composition of the present invention can be used for caring for keratin materials.
  • the present invention provides a non-therapeutic method for caring for keratin materials, comprising applying the composition according to the first aspect of the present invention to the keratin materials.
  • compositions of invention examples (IE. ) 1-5 and comparative examples (CE. ) 1-3 in the form of suspension were prepared according to the amounts given in Table 2. The amount of each component is given in%by weight of the total weight of the composition containing it.
  • Polyglyceryl dioleate-10 (and) tocopherol comprises 99.95 wt. %of Polyglyceryl dioleate-10 and 0.05 wt. %tocopherol.
  • compositions of invention examples 1-5 are compositions according to the present invention.
  • Composition of comparative example 1 does not comprise at least one single-chain nonionic surfactant.
  • Composition of comparative example 2 does not comprise at least one double-chain nonionic surfactant.
  • Composition of comparative example 3 does not comprise at least one solid lipid other than compounds of ceramide type.
  • compositions listed above were prepared as follows, taking the composition of invention example 1 as an example:
  • step 3 adding the oil phase obtained in step 1) into water with stirring for about 10 minutes to obtain a suspension;
  • the sizes of particles in suspensions of invention examples (IE. ) 1-5 and comparative examples (CE. ) 1-3 were determined using a Brookhaven dynamic light scattering (DLS) equipment. Each sample was tested in triplicate. The particle sizes of fresh samples and samples stored for 2 months at 4°C, room temperature (20-25°C) and 45°C, respectively were measured to monitor the stability.
  • LDS Brookhaven dynamic light scattering
  • Table 4 shows effective diameter and polydispersity index (PDI) of each suspension of invention examples 1-5 and comparative examples 1-3 after 2 months storage.
  • Effective diameter average diameter.
  • unmeasurable means samples are too turbid/cloudy to be measured due to too many large particles.
  • the effective diameter When the effective diameter is less than 110 nm, the appearance of the suspension is translusent. When the effective diameter is between 110 nm and 500 nm, the appearance of the suspension is semi-translusent.
  • the sample was regarded as ‘stable’ , otherwise, the sample was regarded as "unstable” .
  • Table 5 shows the stability of each suspension of invention examples 1-5.
  • Table 6 shows the stability of each suspension of comparative examples 1-3.
  • suspension of invention examples 1-5 have translucent or semi-transluent appearance and is stable for at least 2 months, while suspensions of comparative examples 1-3 are not stable.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
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  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne une composition, de préférence pour le soin des matières kératiniques, comprenant : (i) au moins un composé de type céramide ; (ii) au moins un lipide solide autre que des composés de type céramide ; (iii) au moins un tensioactif non ionique à double chaîne ; et (iv) au moins un tensioactif non ionique à chaîne unique. L'invention concerne également un procédé non thérapeutique de soin des matières kératiniques, comprenant l'application de ladite composition sur la peau.
PCT/CN2023/130075 2023-11-07 2023-11-07 Composition pour le soin des matières kératiniques Pending WO2025097289A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
PCT/CN2023/130075 WO2025097289A1 (fr) 2023-11-07 2023-11-07 Composition pour le soin des matières kératiniques
FR2313895A FR3154920A3 (fr) 2023-11-07 2023-12-11 Composition de soin de matières kératineuses

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2023/130075 WO2025097289A1 (fr) 2023-11-07 2023-11-07 Composition pour le soin des matières kératiniques

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Publication Number Publication Date
WO2025097289A1 true WO2025097289A1 (fr) 2025-05-15

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WO2008043386A1 (fr) * 2006-10-13 2008-04-17 Evonik Goldschmidt Gmbh Composition de traitement cutané
WO2018097303A1 (fr) * 2016-11-28 2018-05-31 L'oreal Composition sous forme de nano-émulsion ou de micro-émulsion
WO2018177730A1 (fr) * 2017-03-27 2018-10-04 Evonik Degussa Gmbh Procédé et produit pour la production de formulations contenant des céramides
WO2020129920A1 (fr) * 2018-12-18 2020-06-25 株式会社ジェヌインＲ＆Ｄ Composition de dispersion de céramide
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