WO2025094941A9 - Harmful organism control composition for agricultural and horticultural use (excluding harmful organism control composition for paddy-field rice), and control method using same - Google Patents

Abstract

The present disclosure addresses the problem of providing: a novel harmful organism control composition for agricultural and horticultural use, which has a synergistic control effect in cultivation of plants excluding paddy-field rice; and a control method using the harmful organism control composition. The present disclosure relates to a harmful organism control composition for agricultural and horticultural use (excluding a harmful organism control composition for paddy-field rice), which comprises: (A) saccharin and/or a salt thereof; and at least one plant treatment composition selected from the group consisting of (B) an insecticidal active compound and (C) a bactericidal active compound.

Description

Agricultural and horticultural pest control composition (excluding pest control composition for paddy rice) and control method using the same

This disclosure relates to agricultural and horticultural pest control compositions (excluding pest control compositions for paddy rice) and pest control methods using the same.

Traditionally, various pesticides have been used to increase crop yields and improve crop quality. For example, harmful organisms to be controlled in field crops include plant pathogens such as soft rot, black spot bacterial disease, and downy mildew; plant pathogens such as viruses and viroids; pests of the orders Coleoptera, Hemiptera, Diptera, Thysanoptera, and Lepidoptera; mollusks such as slugs; and nematodes such as Meloidogyne incognita. Numerous compositions and methods of using the same aimed at controlling these harmful organisms have been proposed (for example, Non-Patent Document 1 and Patent Document 1).

Non-Patent Document 1 describes that saccharin has an effect of suppressing disease caused by Zymoseptoria tritici in wheat. Thus, it is already known that saccharin is effective against various plant diseases.
Patent Document 1 discloses a fungicide composition containing pyriophenone and at least one fungicide selected from the group consisting of bixafen, fluxapyroxad, penflufen, isopyrazam, fluopyram, amethoctrazine, fenpyrazamine, and sedaxane.

JP 2013-35823 A

Samara Mejri, Plant disease, Vol. 105, No. 4, April 2021

Repeated use of a single germicide leads to the development of resistance to that and related germicides, and therefore research is being conducted to produce safer and more effective germicides and germicide compositions.
An objective of the present disclosure is to provide a novel agricultural and horticultural pest control composition having a synergistic control effect in the cultivation of plants other than rice, and a control method using the same.

As a result of extensive research into solving the above problems, the inventors have discovered that harmful organisms in plants other than rice can be effectively eliminated by treating plants with a composition in which saccharin, a salt thereof, or a mixture thereof is mixed with an insecticide or a fungicide. The present disclosure has been completed based on this knowledge.

[Correction under Rule 91 25.04.2025]
That is, the present disclosure is as follows.
Item 1.
(A) saccharin and/or a salt thereof;
An agricultural and horticultural pest control composition (excluding pest control compositions for paddy rice) containing at least one plant treatment composition selected from the group consisting of (B) an insecticidally active compound and (C) a fungicidal compound.
Item 2.
The agricultural and horticultural pest control composition comprises (A) saccharin and/or a salt thereof,
Item 2. The agricultural and horticultural pest control composition according to Item 1 (excluding pest control compositions for paddy rice), comprising the (C) fungicidal compound.
Item 3.
Item 3. The agricultural and horticultural pest control composition according to Item 1 or 2, wherein the (C) fungicidal compound is an antibiotic for agricultural chemicals (excluding pest control compositions for paddy rice).
Item 4.
Item 4. The agricultural and horticultural pest control composition according to Item 3, wherein the agricultural antibiotic comprises at least one antibiotic selected from the group consisting of chitin synthase inhibitors, enopyranuronic acid antibiotics, hexopyranosyl antibiotics, glucopyranosyl antibiotics, tetracycline antibiotics, and amphoteric macrolide antifungal antibiotics (excluding pest control compositions for paddy rice).
Item 5.
The agricultural antibiotic is at least one compound or a salt thereof selected from the group consisting of polyoxin, kasugamycin, validamycin, streptomycin and oxytetracycline;
Item 5. The agricultural and horticultural pest control composition according to Item 3 or 4 (excluding pest control compositions for paddy rice).
Item 6.
Item 6. The agricultural and horticultural pest control composition according to any one of Items 3 to 5, wherein the agricultural antibiotic is polyoxin or a salt thereof (excluding pest control compositions for paddy rice).
Section 7.
The insecticidal compound (B) is
(b1) acetylcholinesterase (AChE) inhibitors,
(b2) GABA-gated chloride ion channel blockers,
(b3) a sodium channel modulator,
(b4) nicotinic acetylcholine receptor (nAChR) competitive modulators;
(b5) nicotinic acetylcholine receptor (nAChR) allosteric modulators - site I;
(b6) glutamate-gated chloride channel (GluCl) allosteric modulators;
(b7) juvenile hormone mimetics,
(b8) other non-specific (multi-site) inhibitors;
(b9) chordotonal organ TRPV channel modulators;
(b10) a mite growth inhibitor acting on CHS1;
(b11) an insect midgut membrane disrupting agent derived from a microorganism,
(b12) mitochondrial ATP synthase inhibitors,
(b13) oxidative phosphorylation uncouplers that disrupt the proton gradient;
(b14) nicotinic acetylcholine receptor (nAChR) channel blockers,
(b15) a chitin biosynthesis inhibitor acting on CHS1;
(b16) chitin biosynthesis inhibitor (type 1),
(b17) molting inhibitors (Diptera),
(b18) ecdysone receptor agonists,
(b19) octopamine receptor agonists,
(b20) mitochondrial electron transport complex III inhibitor-Qo site,
(b21) mitochondrial electron transport complex I inhibitors (METIs),
(b22) voltage-dependent sodium channel blockers,
(b23) acetyl CoA carboxylase inhibitors,
(b24) mitochondrial electron transport chain complex IV inhibitors,
(b25) mitochondrial electron transport complex II inhibitors,
(b26) ryanodine receptor modulators,
(b27) chordotonal organ nicotinamidase inhibitors,
(b28) GABA-gated chloride ion channel allosteric modulators,
(b29) baculovirus,
(b30) nicotinic acetylcholine receptor (nAChR) allosteric modulators - site II;
(b31) calcium-activated potassium channel (KCa2) modulators,
(b32) mitochondrial electron transport complex III inhibitor-Qi site,
(b33) targeted suppressors via RNA interference;
(b34) a chordotonal organ modulator (unspecified target site); and (b35) at least one compound selected from the group consisting of an agent A with an unknown or uncertain mechanism of action, a bacterial agent (excluding BT agents) with an unknown or uncertain mechanism of action, a plant-derived component including a synthetic product, extract, or unrefined oil with an unknown or uncertain mechanism of action, a fungal agent with an unknown or uncertain mechanism of action, and a physical perturbation with an unknown or uncertain mechanism of action,
The bactericidal active compound (C) is
(c1) RNA polymerase I inhibitors,
(c2) DNA/RNA biosynthesis inhibitors,
(c3) DNA topoisomerase type II (gyrase) inhibitors,
(c4) dihydroorotate dehydrogenase inhibitors in de novo pyrimidine biosynthesis,
(c5) tubulin polymerization inhibitors,
(c6) cell division (unknown site of action) inhibitor,
(c7) a spectrin-like protein delocalizer;
(c8) inhibitors of actin/myosin/fimbrin function,
(c9) complex I (NADH oxidoreductase) inhibitors,
(c10) complex II (succinate dehydrogenase) inhibitors,
(c11) complex III (ubiquinol oxidase Qo site) inhibitors,
(c12) complex III (ubiquinone reductase Qi site) inhibitors,
(c13) an uncoupler of oxidative phosphorylation,
(c14) complex III (ubiquinone reductase Qo site stigmatellin binding subsite) inhibitors,
(c15) a methionine biosynthesis inhibitor,
(c16) protein biosynthesis (ribosome translation initiation step) inhibitors,
(c17) protein biosynthesis (ribosome polypeptide elongation step) inhibitors,
(c18) MAP histidine kinase (os-2, HOG1) inhibitor in osmotic signal transduction;
(c19) MAP histidine kinase (os-1, Daf1) inhibitor in osmotic signal transduction;
(c20) methyltransferase inhibitors of phospholipid biosynthesis,
(c21) an inhibitor of cellular lipid peroxidation,
(c22) a cell membrane-permeable fatty acid inhibitor,
(c23) lipid homeostasis and transport/storage inhibitors,
(c24) a C14 demethylase inhibitor in sterol biosynthesis,
(c25) a 3-ketoreductase inhibitor in the C4 demethylation of sterol biosynthesis,
(c26) squalene epoxidase inhibitors of sterol biosynthesis,
(c27) chitin biosynthetic enzyme inhibitors,
(c28) cellulose biosynthetic enzyme inhibitors,
(c29) melanin biosynthesis reductase inhibitors,
(c30) a dehydratase inhibitor in melanin biosynthesis,
(c31) polyketamide synthase inhibitors in melanin biosynthesis,
(c32) resistance inducers for host plants (excluding saccharin or its salts),
(c33) compounds with unknown mechanism of action,
(c34) at least one compound selected from the group consisting of multi-site contact active compounds, and (c35) unclassified compounds;
Item 7. The agricultural and horticultural pest control composition according to any one of Items 1 to 6 (excluding pest control compositions for paddy rice).
Section 8.
The insecticidal compound (B) is
(b1) acetylcholinesterase (AChE) inhibitors,
(b2) GABAergic chloride ion (chloride ion) channel blockers,
(b3) a sodium channel modulator,
(b4) nicotinic acetylcholine receptor (nAChR) competitive modulators;
(b5) nicotinic acetylcholine receptor (nAChR) allosteric modulators - site I;
(b9) chordotonal organ TRPV channel modulators;
(b14) nicotinic acetylcholine receptor (nAChR) channel blockers,
(b16) chitin biosynthesis inhibitor (type 1),
(b18) ecdysone receptor agonists,
(b26) a ryanodine receptor modulator, and (b33) at least one compound selected from the group consisting of oxazosulfil, benzpyrimoxane, and isocyclohexameram;
The bactericidal active compound (C) is
(c1) RNA polymerase I inhibitors,
(c2) DNA/RNA biosynthesis inhibitors,
(c3) DNA topoisomerase type II (gyrase) inhibitors,
(c4) dihydroorotate dehydrogenase inhibitors in de novo pyrimidine biosynthesis,
(c5) tubulin polymerization inhibitors,
(c6) cell division (unknown site of action) inhibitor,
(c10) complex II (succinate dehydrogenase) inhibitors,
(c11) complex III (ubiquinol oxidase Qo site) inhibitors,
(c12) complex III (ubiquinone reductase Qi site) inhibitors,
(c16) protein biosynthesis (ribosome translation initiation step) inhibitors,
(c17) protein biosynthesis (ribosome polypeptide elongation step) inhibitors,
(c20) methyltransferase inhibitors of phospholipid biosynthesis,
(c24) a C14 demethylase inhibitor in sterol biosynthesis,
(c27) chitin biosynthetic enzyme inhibitors,
(c29) melanin biosynthesis reductase inhibitors,
(c31) polyketamide synthase inhibitors in melanin biosynthesis,
(c32) resistance inducers for host plants (excluding saccharin or its salts),
(c33) compounds with unknown mechanism of action,
(c34) multisite contact active compounds, and (c35) at least one compound selected from the group consisting of quinofumelin;
Item 8. The agricultural and horticultural pest control composition according to any one of Items 1 to 7 (excluding pest control compositions for paddy rice).
Item 9.
(A) saccharin and/or a salt thereof;
A method for controlling pests (excluding methods for controlling pests in paddy rice), the method comprising the step of applying a composition containing at least one plant treatment composition selected from the group consisting of (B) an insecticidally active compound and (C) a fungicidal compound to pests, a habitat of pests, plants, or a cultivation carrier of plants.
Item 10.
(A) saccharin and/or a salt thereof;
Use of a composition containing (B) an insecticidal compound and (C) at least one plant treatment composition selected from the group consisting of a fungicidal compound, for agricultural and horticultural pest control (excluding use for pest control in paddy rice).

According to the present disclosure, it is possible to provide a novel agricultural and horticultural pest control composition (excluding pest control compositions for paddy rice) that exhibits a remarkable synergistic plant disease control effect that cannot be predicted from the plant disease control effect obtained by using only saccharin or its salts, or mixtures thereof, or by using only a plant treatment composition.

Agricultural and horticultural pest control compositions (excluding pest control compositions for paddy rice)
The agricultural and horticultural pest control composition of the present disclosure (excluding pest control compositions for paddy rice) (hereinafter sometimes referred to as the "composition of the present disclosure") is,
(A) saccharin and/or a salt thereof;
and (B) at least one plant treatment composition selected from the group consisting of an insecticidal compound and (C) a fungicidal compound.
The agricultural and horticultural pest control composition of the present disclosure (excluding pest control compositions for paddy rice) comprises (A) saccharin and/or a salt thereof,
By using the plant treatment composition as a mixture in combination with at least one plant treatment composition selected from the group consisting of (B) an insecticidal compound and (C) a fungicidal compound, excellent pest control effects are achieved in the cultivation of plants other than rice.

(A) Saccharin and/or its salts Saccharin (1,1-dioxo-1,2-benzothiazol-3-one) is a compound represented by the following formula (1). Saccharin is generally used as an artificial sweetener, but is known to have resistance induction activity and can exert a disease suppression effect by inducing resistance against diseases in a host plant (activating the disease control system).

The salt of saccharin may be any type of salt, provided that it is agriculturally acceptable. Examples of such salts include inorganic acids (e.g., hydrochloride, sulfate, nitrate, etc.), organic acids (e.g., acetate, methanesulfonate, etc.), alkali metal salts (e.g., sodium salt, potassium salt, etc.), alkaline earth metal salts (e.g., calcium salt, etc.), and quaternary ammonium salts (e.g., tetramethylammonium salt, tetraethylammonium salt, etc.), with alkali metal salts being preferred and sodium salts being more preferred.

The application amount and concentration of the disclosed composition can be changed depending on weather conditions, application time, application location, application method, etc., but the application amount of saccharin and/or its salts is usually 0.05 to 300 g/a, preferably 0.1 to 100 g/a, and more preferably 0.15 to 50 g/a. However, this does not apply when applied to crops before planting in cell trays, seedling pots, etc.

Plant Treatment Composition The disclosed composition comprises at least one plant treatment composition selected from the group consisting of (B) an insecticidally active compound and (C) a fungicidalally active compound.

(B) Insecticidally active compound The insecticidal compound contained in the agricultural and horticultural pest control composition of the present disclosure (excluding the pest control composition for rice) can be any compound known to have a control effect against agricultural pests, without any particular limitation. The insecticidal compound here includes not only insecticides, but also miticides and nematocides. The insecticidal compound can be formulated alone or in a suitable mixture of two or more kinds.

(B) There are no particular limitations on the insecticidal compounds, and examples of such compounds include those belonging to groups 1 to 36 and groups UN to UNM in the insecticide resistance action committee (IRAC) action classification.

(b1) Group 1: Acetylcholinesterase (AChE) inhibitors . Examples of acetylcholinesterase (AChE) inhibitors include alanycarb, aldicarb, bendiocarb, benfuracarb, butocarboxim, butoxycarboxim, carbaryl (NAC), carbofuran, carbosulfan, and ethiphen. Ethiofencarb, fenobucarb (BPMC), formetanate, furathiocarb, isoprocarb (MIPC), methiocarb, methomyl, metolcarb (MTMC), oxamyl, pirimicarb, propoxur (PHC), thiodicarb, thiofanox ox), triazamate, trimethacarb, XMC, xylylcarb (MPMC) and other carbamate compounds (1A); acephate, azamethiphos, azinphos-ethyl, azinphos-methyl, cadusafos, chlorethoxyfos, chlorfenvinphos (CVP), chlormethamine, ... Chlormephos, chlorpyrifos, chlorpyrifos-methyl, coumaphos, cyanophos (CYAP), demeton-S-methyl, diazinon, dichlorvos (DDVP), dicrotophos, dimethoate, dimethylvinphos, ethylthiometon (disulfoton ) (disulfoton), EPN, ethion, ethoprophos, famphur, fenamiphos, fenitrothion (MEP), fenthion (MPP), fosthiazate, heptenophos, imicyaphos, isofenphos, isopropyl-O-(methoxyaminothiophosphoryl) salicylate (isopropyl-O-( methoxyaminothiophosphoryl salicylate), isoxathion, malathion, mecarbam, methamidophos, methidathion (DMTP), mevinphos, monocrotophos, naled (BRP), omethoate, oxydemeton-methyl, parathion (p arathion), methyl parathion (parathion-methyl), phenthoate (PAP), phorate, phosalone, phosmet (PMP), phosphamidon, phoxim, pirimiphos-methyl, profenofos, propetamphos, prothiofos, pyraclofos ofos), pyridaphenthion, quinalphos, sulfotep, tebupirimfos, temephos, terbufos, tetrachlorvinphos (CVMP), thiometon, triazophos, trichlorfon (DEP), vamidothion and other organophosphorus compounds (1B).

(b2) Group 2: GABA-activated chloride ion (chloride ion) channel blockers Examples of the GABA-activated chloride ion (chloride ion) channel blockers include cyclic diene organic chlorine compounds (2A) such as chlordane and benzoepin (endosulfan); phenylpyrazole (fiprole) compounds (2B) such as ethiprole and fipronil.

(b3) Group 3: Sodium Channel Modulators Examples of sodium channel modulators include acrinathrin, allethrin (allethrin, d-cis-trans-, d-trans-isomers), bifenthrin, bioallethrin (bioallethrin, S-cyclopentenyl isomers), bioresmethrin, cycloprothrin, and cyfluthrin. , β-isomer), cyhalothrin (cyhalothrin, λ-, γ-isomers), cypermethrin (cypermethrin, α-, β-, θ-, ζ-isomers), cyphenothrin [(1R)-trans isomer], deltamethrin, empenthrin [(EZ)-(1R)-trans isomer], esfenvalerate, etofenprox , fenpropathrin, fenvalerate, flucythrinate, flumethrin, fluvalinate (τ-fluvalinate), halfenprox, imiprothrin, kadethrin, permethrin, phenothrin [(1R)-trans isomer], prallethrin pyrethroid (pyrethrin) compounds (3A) such as lethrin, pyrethrins, resmethrin, silafluofen, tefluthrin, phthalthrin (tetramethrin), tetramethrin [(1R)-trans isomer], tralomethrin, and transfluthrin; DDT and methoxychlor (3B).

(b4) Group 4: Nicotinic acetylcholine receptor (nAChR) competitive modulators Examples of nicotinic acetylcholine receptor (nAChR) competitive modulators include, for example, neonicotinoids such as acetamiprid, clothianidin, dinotefuran, imidacloprid, nitenpyram, thiacloprid, and thiamethoxam. nicotine compounds (4B) such as nicotine sulfate (nicotine); sulfoximine compounds (4C) such as sulfoxaflor; butenolide compounds (4D) such as flupyradifurone; mesoion compounds (4E) such as dichloromezotiaz, phenmezoditiaz, triflumezopyrim; and pyridylidene compounds (4F) such as flupirimine.

(b5) Group 5: Nicotinic acetylcholine receptor (nAChR) allosteric modulators - Site I
Nicotinic acetylcholine receptor (nAChR) allosteric modulators - site I include, for example, spinosyn compounds such as spinetoram and spinosad.

(b6) Group 6: Glutamate-gated chloride channel (GluCl) allosteric modulators Examples of glutamate-gated chloride channel (GluCl) allosteric modulators include avermectin compounds such as abamectin, and milbemycin compounds such as emamectin benzoate, lepimectin, and milbemectin.

(b7) Group 7: Juvenile hormone mimetics Juvenile hormone mimetics include, for example, juvenile hormone analogues such as hydroprene, kinoprene, methoprene, etc. (7A); fenoxycarb (7B); pyriproxyfen (7C); etc.

(b8) Group 8: Other non-specific (multi-site) inhibitors Examples of other non-specific (multi-site) inhibitors include alkyl halide compounds (8A) such as 1,3-dichloropropene, methyl bromide, and other alkyl halides; chloropicrin (8B); fluoride compounds (8C) such as cryolite (sodium aluminum fluoride) and sulfuryl fluoride; borax, boric acid, disodium octaborate, sodium borate, and sodium metaborate; tartar emetic (8E); methyl isothiocyanate generators (8F) such as dazomet, metam, and methyl isothiocyanate.

(b9) Group 9: Chordotonal Organ TRPV Channel Modulators Examples of chordotonal organ TRPV channel modulators include pyridine azomethine derivatives (9B) such as pymetrozine and pyrifluquinazon; pyropene compounds (9D) such as afidopyropen, and the like.

(b10) Group 10: mite growth inhibitors acting on CHS1 . Examples of mite growth inhibitors acting on CHS1 include clofentezine, diflovidazin, hexythiazox, etc. (10A); etoxazole (10B), etc.

(b11) Group 11: Microorganism-derived insect midgut inner membrane disrupting agents Examples of microorganism-derived insect midgut inner membrane disrupting agents include Bacillus thuringiensis subsp. israelensis, Bacillus thuringiensis subsp. Aizawai, Bacillus thuringiensis subsp. Kurstaki, and Bacillus thuringiensis subsp. tenebrionis (proteins contained in Bt crops: Cry1Ab, Cry1Ac, Cry1Fa, Cry1A.105, Cry2Ab, Vip3A, mCry3A, Cry2Ab, Cry3Bb, Cry34Ab1/Cry35Ab1). thuringiensis and the insecticidal protein it produces (11A); Bacillus sphaericus (11B); and the like.

(b12) Group 12: Mitochondrial ATP synthase inhibitors Examples of mitochondrial ATP synthase inhibitors include diafenthiuron (12A); organotin acaricides such as azocyclotin, tricyclohexyltin hydroxide (cyhexatin), and fenbutatin oxide (12B); propargite (BPPS) (12C); and tetradifon (12D).

(b13) Group 13: Oxidative phosphorylation uncouplers that disrupt the proton gradient Examples of oxidative phosphorylation uncouplers that disrupt the proton gradient include pyrrole compounds such as chlorfenapyr; dinitrophenol compounds such as DNOC; sulfluramid; and the like.

(b14) Group 14: Nicotinic acetylcholine receptor (nAChR) channel blockers Examples of nicotinic acetylcholine receptor (nAChR) channel blockers include nereistoxin analogues such as bensultap, cartap hydrochloride, thiocyclam, and thiosultapsodium.

(b15) Group 15: Chitin Biosynthesis Inhibitors Acting on CHS1 Examples of chitin biosynthesis inhibitors acting on CHS1 include benzoylurea compounds such as bistrifluron, chlorfluazuron, diflubenzuron, flucycloxuron, flufenoxuron, hexaflumuron, lufenuron, novaluron, noviflumuron, teflubenzuron, and triflumuron.

(b16) Group 16: chitin biosynthesis inhibitors (type 1)
Chitin biosynthesis inhibitors (type 1) include, for example, buprofezin.

(b17) Group 17: molting inhibitors (Diptera )
Molting inhibitors (Diptera) include, for example, cyromazine.

(b18) Group 18: Ecdysone Receptor Agonists Examples of the ecdysone receptor agonists include diacyl-hydrazine compounds such as chromafenozide, halofenozide, methoxyfenozide, and tebufenozide.

(b19) Group 19: Octopamine Receptor Agonists Examples of octopamine receptor agonists include amitraz.

(b20) Group 20: mitochondrial electron transport complex III inhibitors-Qo site Examples of mitochondrial electron transport complex III inhibitors-Qo site include hydramethylnon (20A), acequinocyl (20B), fluacrypyrim (20C), bifenazate (20D), and the like.

(b21) Group 21: mitochondrial electron transport complex I inhibitors (METI)
Examples of mitochondrial electron transport complex I inhibitors (METI) include METI agents such as fenazaquin, fenpyroximate, pyridaben, pyrimidifen, tebufenpyrad, and tolfenpyrad (21A); and derris (rotenone) (21B).

(b22) Group 22: Voltage-dependent sodium channel blockers Examples of the voltage-dependent sodium channel blockers include oxadiazine compounds (22A) such as indoxacarb; semicarbazone compounds (22B) such as metaflumizone; and the like.

(b23) Group 23: Acetyl-CoA Carboxylase Inhibitors Examples of acetyl-CoA carboxylase inhibitors include tetronic acid or tetramic acid derivatives such as spirodiclofen, spiromesifen, spiropidione, and spirotetramat.

(b24) Group 24: mitochondrial electron transport complex IV inhibitors Examples of mitochondrial electron transport complex IV inhibitors include phosphine compounds (24A) such as aluminum phosphide, calcium phosphide, hydrogen phosphide, zinc phosphide, etc.; cyanides (24B) such as hydrocyanic acid (calcium cyanide, sodium cyanide), potassium cyanide, etc.

(b25) Group 25: mitochondrial electron transport complex II inhibitors Examples of mitochondrial electron transport complex II inhibitors include β-ketonitrile derivatives (25A) such as cyenopyrafen and cyflumetofen; carboxanilide compounds (25B) such as pyflubumide.

(b26) Group 28: Ryanodine Receptor Modulators Examples of ryanodine receptor modulators include diamide compounds such as chlorantraniliprole, cyantraniliprole, cycloniliprole, flubendiamide, and tetraniliprole.

(b27) Group 29: Chordotonal organ modulators Examples of chordotonal organ modulators include flonicamid and the like.

(b28) Group 30: GABA-gated chloride ion channel allosteric modulators Examples of the GABA-gated chloride ion channel allosteric modulators include metadiamide compounds such as broflanilide, and isoxazoline compounds such as fluxametamide and isocycloseram.

(b29) Group 31: Baculoviruses Examples of baculoviruses include granulosis viruses (GVs) such as codling moth Cydia pomonella GV and codling moth Thaumatotibia leucotreta GV, polyhedrosis viruses (NPVs) such as bean caterpillar Anticarsia gemmatalis MNPV and cotton bollworm Helicoverpa armigera NPV, and the like.

(b30) Group 32: Nicotinic acetylcholine receptor (nAChR) allosteric modulators - Site II
Nicotinic acetylcholine receptor (nAChR) allosteric modulators - site II include, for example, GS-omega/kappa HXTX-Hv1a peptide and the like.

(b31) Group 33: Calcium-activated potassium channel (KCa2) modulators Examples of calcium-activated potassium channel (KCa2) modulators include acinonapyr.

(b32) Group 34: mitochondrial electron transport complex III inhibitor-Qi site Examples of mitochondrial electron transport complex III inhibitor-Qi site include flometoquin.

(b33) Group 35: Targeted Inhibitors Mediated by RNA Interference Examples of targeted inhibitors mediating RNA interference include Ledprona.

(b34) Group 36: Chordotonal organ modulators (target site unspecified)
Chordotonal organ modulators (target site undefined) include, for example, pyridazine or pyrazole carboxamides, such as dimpropyridaz.

(b35) Group UN: Agents A with unknown or unclear mechanism of action
Examples of agent A with an unknown or unclear mechanism of action include azadirachtin, benzoximate, benzpyrimoxan, bromopropylate, quinomethionat, dicofol, lime sulfur mixture, manzeb, oxazosulfyl, pyridalyl, sulfur, and the like.
(b36) Group UNB: Bacterial agents with unknown or unclear mechanism of action (excluding BT agents)
Examples of bacterial agents (excluding BT agents) whose mechanism of action is unknown or unclear include Burkholderia spp., Wolbachia pipientis (Zap), and the like.
(b37) Group UNE: Plant-derived components including synthetic substances, extracts, and unrefined oils with an unknown or unclear mechanism of action. Examples of plant-derived components including synthetic substances, extracts, and unrefined oils with an unknown or unclear mechanism of action include, for example, Chenopodium ambrosioides near ambrosioides, extracts of American burdock, and fatty acid monoesters of glycerin or propanediol in neem oil.
(b38) Group UNF: fungicides with unknown or unclear mechanism of action . Examples of fungicides with unknown or unclear mechanism of action include Akanthomyces muscarius Ve6, Beauveria bassiana strains, Metarhizium brunneum strain F52, Paecilomyces fumosoroseus Apopka strain 97, etc.
(b39) Group UNM: non-specific physical perturbations with unknown or unclear mechanism of action. Examples of non-specific physical perturbations with unknown or unclear mechanism of action include diatomaceous earth, mineral oil, etc.

Other examples include known agricultural and horticultural insecticides. These insecticidal compounds are known compounds and are commercially available, so they are easily available.

In the present disclosure, (B) an insecticidal active compound is typically mixed in an amount of 0.01 to 20,000 parts by mass, preferably 0.1 to 10,000 parts by mass, and more preferably 0.5 to 1,000 parts by mass, per 100 parts by mass of (A) saccharin and/or its salt.

(C) Fungicidal Compounds The fungicidal compounds contained in the agricultural and horticultural pest control compositions of the present disclosure (excluding the pest control compositions for paddy rice) can be any known compounds having a control effect against agricultural pests, without any particular restrictions. The fungicidal compounds referred to here include not only fungicides, but also bactericides and virucides. The fungicidal compounds can be used alone or in a suitable mixture of two or more kinds.

(C) The fungicidal active compounds are not particularly limited, and examples thereof include compounds that belong to the following groups in the action classification by FRAC (Fungicide Resistance Action Committee): A (nucleic acid synthesis metabolism), B (cytoskeleton and motor proteins), C (respiration), D (amino acid and protein biosynthesis), E (signal transduction), F (lipid biosynthesis or transport/cell membrane structure or function), G (cell membrane sterol biosynthesis), H (cell wall biosynthesis), I (cell wall melanin biosynthesis), P (host plant resistance induction), M (multiple action site contact active compounds), BM (biopesticides with multiple action mechanisms: plant extracts), U (action mechanism unknown), and unclassified. Among these, the following groups A, B, C, D, F, G, I, P, M, and U are preferred.

Group A Group A (nucleic acid synthesis metabolism) includes, for example, RNA polymerase I inhibitors, adenosine deaminase, DNA/RNA biosynthesis inhibitors, DNA topoisomerase type II (gyrase) inhibitors, and dihydroorotate dehydrogenase inhibitors in de novo pyrimidine biosynthesis.

(c1) Group A1: RNA polymerase I inhibitors (FRAC group code 4)
Examples of RNA polymerase I inhibitors include acylalanines such as benalaxyl, benalaxyl-M, furalaxyl, metalaxyl, and metalaxyl-M; oxazolidinones such as oxadixyl; and butyrolactones such as ofurace.

(c2) Group A2: Adenosine deaminase inhibitors (FRAC group code 8)
Adenosine deaminase inhibitors include, for example, hydroxy(2-amino-)pyrimidines such as bupirimate, dimethirimol, and ethirimol.

(c3) Group A3: DNA/RNA biosynthesis inhibitors (FRAC group code 32)
Examples of DNA/RNA biosynthesis inhibitors include isoxazoles such as hydroxyisoxazole (hymexazole), and isothiazolones such as octhilinone.

(c4) Group A4: DNA topoisomerase type II (gyrase) inhibitors (FRAC group code 31)
Examples of DNA topoisomerase type II (gyrase) inhibitors include carboxylic acids such as oxolinic acid.
(c5) Group A5: Dihydroorotate dehydrogenase inhibitors in de novo pyrimidine biosynthesis (FRAC group code 52)
Examples of dihydroorotate dehydrogenase inhibitors in de novo pyrimidine biosynthesis include phenylpropanols such as ipflufenoquine, and dihydroisoquinolines such as quinofumelin.

Group B Group B (cytoskeleton and motor proteins) includes, for example, tubulin polymerization inhibitors, cell division (unknown site of action) inhibitors, delocalizing agents for spectrin-like proteins, inhibitors of actin/myosin/fimbrin functions, tubulin dynamics modulators, etc.

(c6) Groups B1, B2, B3: tubulin polymerization inhibitors (FRAC group codes 1, 10, 22)
Examples of β-tubulin polymerization inhibitors include benzimidazoles such as benomyl, carbendazim, fuberidazole, and thiabendazole; thiophanates such as thiophanate and thiophanate-methyl; N-phenylcarbamates such as diethofencarb; toluamides such as zoxamide; and ethylaminothiazolecarboxamides such as ethaboxam.

(c7) Group B4: Cell division (unknown site of action) inhibitors (FRAC group code 20)
Examples of inhibitors of cell division (unknown site of action) include phenylureas such as pencycuron.

(c8) Group B5: spectrin-like protein delocalizers (FRAC group code 43)
Examples of delocalizing agents for spectrin-like proteins include pyridinylmethylbenzamides such as fluopicolide and fluopimomide.

(c9) Group B6: inhibitors of actin/myosin/fimbrin function (FRAC group code 47)
Examples of inhibitors of actin/myosin/fimbrin functions include aminocyanoacrylates such as phenamacril; benzophenones such as metrafenone; benzoylpyridines such as pyriophenone; and the like.

(c10) Group B7: Tubulin dynamics modulators (FRAC group code 53)
Examples of tubulin dynamics modulators include pyridazines such as pyridachlometyl.

C Group Examples of C Group (respiration) include complex I (NADH oxidoreductase) inhibitors, complex II (succinate dehydrogenase) inhibitors, complex III (cytochrome bc1 (ubiquinol oxidase) Qo site (cytb gene)) inhibitors, complex III (ubiquinone reductase Qi site) inhibitors, uncouplers of oxidative phosphorylation, inhibitors of oxidative phosphorylation and ATP synthase, ATP transport inhibitors, and complex III (ubiquinone reductase Q1, Qo site, stigmatellin binding mode) inhibitors.

(c11) Group C1: Complex I (NADH oxidoreductase) inhibitors (FRAC group code 39)
Examples of complex I (NADH oxidoreductase) inhibitors include pyrimidineamines such as diflumetorim; pyrazolecarboxamides such as tolfenpyrad; quinazolines such as fenazaquin; and the like.

(c12) Group C2: Complex II (succinate dehydrogenase) inhibitors (FRAC group code 7)
Examples of complex II (succinate dehydrogenase) inhibitors include phenylbenzamides such as benodanil, flutolanil, and mepronil; phenyloxoethylthiophenamides such as isofetamide; pyridinylethylbenzamides such as fluopyram; phenylcyclobutylpyridine amides such as cyclobutrifluram; furancarboxamides such as fenfuram; oxathiincarboxamides such as carboxin and oxycarboxin; thiazolecarboxamides such as thifluzamide; benzovindiflupyr, Examples of such pyrazole-4-carboxamides include bixafen, fluindapyr, fluxapyroxad, furametpyr, impirfluxam, isopyrazam, penflufen, penthiopyrad, and sedaxane; N-cyclopropyl-N-benzylpyrazolecarboxamides such as isoflucipram; N-methoxy(phenylethyl)pyrazolecarboxamides such as pydiflumetofen; pyridinecarboxamides such as boscalid; and pyrazinecarboxamides such as pyraziflumide.

(c13) Group C3: Complex III (cytochrome bc1 (ubiquinol oxidase) Qo site (cytb gene)) inhibitors Complex III (cytochrome bc1 (ubiquinol oxidase) Qo site (cytb gene)) inhibitors (QoI fungicides (Qo inhibitors)) (FRAC group code 11) include, for example, methoxyacrylates such as azoxystrobin, coumoxystrobin, enoxastrobin, flufenoxystrobin, picoxystrobin, and pyraoxystrobin; methoxyacetamides such as mandestrobin; pyraclostrobin, pyrametostrobin, and triclopyricarb. methoxycarbamates such as kresoxim-methyl and trifloxystrobin; oxyiminoacetamides such as dimoxystrobin, phenaminestrobin, metominostrobin, and orysastrobin; oxazolidinediones such as famoxadone; dihydrodioxazines such as fluoxastrobin; imidazolinones such as fenamidone; and benzylcarbamates such as pyribencarb.
Furthermore, examples of QoI fungicides (Qo inhibitors; subgroup A) (FRAC group code 11A) include tetrazolinones such as methyltetrapyrrole.

(c14) Group C4: Complex III (ubiquinone reductase Qi site) inhibitors (FRAC group code 21)
Examples of complex III (ubiquinone reductase Qi site) inhibitors include cyanoimidazoles such as cyazofamid, etc.; sulfamoyltriazoles such as amisulbrom, etc.; picolinamides such as fenpicoxamid and florylpicoxamid, etc.

(c15) Group C5: Uncouplers of oxidative phosphorylation (FRAC group code 29)
Examples of uncouplers of oxidative phosphorylation include dinitrophenyl crotonic acids such as BINAPACRIL, meptyl dinocap, and DPC (dinocap); 2,6-dinitroanilines such as fluazinam; and pyrimidinone hydrazones such as ferimzone.

(c16) Group C6: Inhibitors of oxidative phosphorylation and ATP synthase (FRAC group code 30)
Examples of inhibitors of oxidative phosphorylation and ATP synthase include triphenyltin compounds such as organotins (triphenyltin acetate, triphenyltin chloride, triphenyltin hydroxide).

(c17) Group C7: ATP transport inhibitors (FRAC group code 38)
Examples of ATP transport inhibitors include thiophenecarboxamides such as silthiofam.

(c18) Group C8: Complex III (ubiquinone reductase Q1, Qo site, stigmatellin binding mode) inhibitors (FRAC group code 45)
Examples of complex III (ubiquinone reductase Q1, Qo sites, stigmatellin binding mode) inhibitors include triazolopyrimidylamines such as ametoctradin.

[Correction under Rule 91 25.04.2025]
Group D Examples of Group D (amino acid and protein biosynthesis inhibitors) include methionine biosynthesis (cgs gene) inhibitors, protein biosynthesis (ribosome translation termination stage) inhibitors, protein biosynthesis (ribosome translation initiation stage) inhibitors, protein biosynthesis (ribosome polypeptide elongation stage) inhibitors, and leucyl-tRNA synthesis (LeuRNA) inhibitors.

(c19-1) Group D1: Methionine biosynthesis (cgs gene) inhibitors (FRAC group code 9)
Examples of methionine biosynthesis (cgs gene) inhibitors include anilinopyrimidines such as cyprodinil, mepanipyrim, and pyrimethanil.

[Correction under Rule 91 25.04.2025]
(c19-2) Group D2: Protein biosynthesis (ribosome translation termination step) inhibitors (FRAC group code 23)
Examples of inhibitors of protein biosynthesis (ribosome translation termination step) include enopyranuronic acid antibiotics such as Blasticidin S.

[Correction under Rule 91 25.04.2025]
(c19-3) Group D3: Protein biosynthesis (ribosome translation initiation stage) inhibitors (FRAC group code 24), Group D4: Protein biosynthesis (ribosome translation initiation stage) inhibitors (FRAC group code 25)
Examples of protein biosynthesis (ribosome translation initiation step) inhibitors include hexopyranosyl antibiotics such as kasugamycin; glucopyranosyl antibiotics such as streptomycin; and the like.

[Correction under Rule 91 25.04.2025]
(c19-4) Group D5: Protein biosynthesis (ribosome polypeptide elongation step) inhibitors (FRAC group code 41)
Examples of inhibitors of protein biosynthesis (ribosomal polypeptide elongation step) include tetracycline antibiotics such as oxytetracycline.

(c19-5) Group D6: Leucyl-tRNA synthesis (LeuRNA) inhibitors (FRAC group code 54)
Leucyl-tRNA synthesis (LeuRNA) inhibitors include, for example, benzoxanboroles such as tavaborole.

Group E Examples of Group E (signal transduction) include signal transduction (mechanism of action unknown) inhibitors, MAP/histidine kinase (os-2, HOG1) inhibitors in osmotic signal transduction, and MAP/histidine kinase (os-1, Daf1) inhibitors in osmotic signal transduction.

(c20) Group E1: Signal transduction (unknown mechanism of action) inhibitors (FRAC group code 13)
Examples of signal transduction (mechanism of action unknown) inhibitors include allyloxyquinolines such as quinoxyfen; quinazolinones such as proquinazid; and the like.

(c21) Group E2: MAP/histidine kinase (os-2, HOG1) inhibitors in osmotic signaling (FRAC group code 12)
Examples of MAP/histidine kinase (os-2, HOG1) inhibitors in osmotic signaling include phenylpyrroles such as fenpiclonil and fludioxonil.

(c22) Group E3: MAP/histidine kinase (os-1, Daf1) inhibitors in osmotic signaling (FRAC group code 2)
Examples of MAP/histidine kinase (os-1, Daf1) inhibitors in osmotic signaling include dicarboximides such as chlozolinate, dimethachlone, iprodione, procymidone, and vinclozolin.

Group F Group F (inhibitors of lipid biosynthesis or transport/cell membrane structure or function) include, for example, methyltransferase inhibitors of phospholipid biosynthesis, inhibitors of cellular lipid peroxidation, fatty acid inhibitors of cell membrane permeability, ergosterol binding agents, inhibitors of lipid homeostasis and transfer/storage, interactions with cell membrane lipid fractions, inhibitors of multiple actions on cell membranes, etc.

(c23) Group F2: phospholipid biosynthesis methyltransferase inhibitors (FRAC group code 6)
Examples of methyltransferase inhibitors for phospholipid biosynthesis include phosphorothiolates such as EDDP (edifenphos), IBP (iprobenfos), and pyrazophos; dithiolanes such as isoprothiolane; and the like.

(c24) Group F3: Inhibitors of cellular lipid peroxidation (FRAC group code 14)
Examples of inhibitors of cellular lipid peroxidation include aromatic hydrocarbons such as biphenyl, chloroneb, CNA (dicloran), PCNB (quintozene), tecnazen, and tolclofos-methyl; and 1,2,4-thiadiazoles such as eclomezole (etridiazole).

(c25) Group F4: cell membrane permeable fatty acid inhibitors (FRAC group code 28)
Examples of cell membrane permeable fatty acid inhibitors include carbamates such as prothiocarb, iodocarb, propamocarb, and propamocarb.

(c26) Group F8: ergosterol binders (FRAC group code 48)
Examples of ergosterol binders include amphoteric macrolide antifungal antibiotics such as natamycin (pimaricin) produced by actinomycetes Streptomyces natalensis or S. chattanoogensis.

(c27) Group F9: inhibitors of lipid homeostasis and transfer/storage (FRAC group code 49)
Inhibitors of lipid homeostasis and transfer/storage include, for example, piperidinyl thiazole isoxazolines such as oxathiapiprolin and fluoxapiprolin.

(c28) Group F10: Interaction with cell membrane lipid fraction, multiple action inhibitors on cell membranes (FRAC group code 51)
Examples of inhibitors of interaction with cell membrane lipid fractions and multiple effects on cell membranes include polypeptides such as ASFBIOF01-02.

G Group : Examples of G group (cell membrane sterol biosynthesis inhibitors) include inhibitors of C14 demethylase (erg11/cyp51) in sterol biosynthesis, inhibitors of ^Δ14 reductase and ^Δ8 → ^Δ7 isomerase (erg24, erg2) in sterol biosynthesis, inhibitors of 3-keto reductase (erg27) in C4 demethylation in sterol biosynthesis, and inhibitors of squalene epoxidase (erg1) in the sterol biosynthesis system.

(c29) Group G1: Inhibitors of C14 demethylase (erg11/cyp51) in sterol biosynthesis (FRAC group code 3)
Inhibitors of C14 demethylase in sterol biosynthesis include, for example, piperazines such as triforine; pyridines such as pyrifenox and pyrisoxazole; pyrimidines such as fenarimol and nuarimol; imazalil, oxypoconazole, pefurazoate, prochloraz, and triflumizole; imidazoles such as azaconazole, bitertanol, bromuconazole, cyproconazole, difenoconazole, diniconazole, epoxiconazole, etaconazole, and fenbuconazole. triazoles such as nbuconazole, fluquinconazole, flusilazole, flutriafol, hexaconazole, imibenconazole, ipconazole, mefentrifluconazole, metconazole, microbutanil, penconazole, propiconazole, simeconazole, tebuconazole, tetraconazole, triadimefon, triadimenol, triticonazole, and the like; triazolinethiones such as prothioconazole, and the like.

(c30) Group G2: Inhibitors of Δ14 reductase and Δ8 →Δ7 isomerase (erg24, erg2) ⁱⁿ sterol ^biosynthesis ( ^FRAC group code 5)
Examples of inhibitors of ^Δ14 reductase and ^Δ8 → ^Δ7 isomerase (erg24, erg2) in sterol biosynthesis include morpholines such as aldimorph, dodemorph, fenpropimorph, tridemorph, etc.; piperidines such as fenpropidin, piperalin, etc.; spiroketalamines such as spiroxamine, etc.

(c31) Group G3: 3-ketoreductase (erg27) inhibitors in the demethylation of C4 position of sterol biosynthesis (FRAC group code 17)
Examples of 3-ketoreductase (erg27) inhibitors in the demethylation of the C4 position of sterol biosynthesis include hydroxyanilides such as fenhexamid; aminopyrazolinones such as fenpyrazamine; and the like.

(c32) Group G4: Inhibitors of squalene epoxidase (erg1) in sterol biosynthesis (FRAC group code 18)
Examples of inhibitors of squalene epoxidase (erg1) in sterol biosynthesis include thiocarbamates such as pyributicarb; and allylamines such as naftifine and terbinafine.

Group H Examples of group H (cell wall biosynthesis inhibitors) include chitin synthase inhibitors and cellulose synthase inhibitors.

(c33) Group H4: chitin synthase inhibitors (FRAC group code 19)
Chitin synthase inhibitors include, for example, peptidyl pyrimidine nucleosides such as polyoxine, which is an agricultural antibiotic. Polyoxine is an antifungal antibiotic produced by the actinomycete Streptomyces cacaoi. There are 14 types of polyoxin, with the main components being A, B, and D.

(c34) Group H5: cellulose synthase inhibitors (FRAC group code 40)
Examples of cellulose synthase inhibitors include cinnamic acid amides such as dimethomorph, flumorph, and pyrimorph; valinamide carbamates such as benthiavalicarb, iprovalicarb, and valifenalate; and mandelic acid amides such as mandipropamide.

Group I Examples of Group I (cell wall melanin synthesis inhibitors) include reductase inhibitors in melanin biosynthesis, dehydratase inhibitors in melanin biosynthesis, and polyketide synthase inhibitors in melanin biosynthesis.

(c35) Group I1: melanin biosynthesis reductase inhibitors (FRAC group code 16.1)
Examples of melanin biosynthesis reductase inhibitors include isobenzofuranones such as fthalide; pyrroloquinolinones such as pyroquilon; and triazolobenzothiazoles such as tricyclazole.

(c36) Group I2: Dehydratase inhibitors of melanin biosynthesis (FRAC group code 16.2)
Examples of dehydratase inhibitors in melanin biosynthesis include cyclopropanecarboxamides such as carpropamid; carboxamides such as diclocymet; propionamides such as fenoxanil; and the like.

(c37) Group I3: polyketide synthase inhibitors of melanin biosynthesis (FRAC group code 16.3)
Examples of polyketide synthase inhibitors in melanin biosynthesis include trifluoroethyl carbamates such as tolprocarb.

P Group
(c38) Resistance inducers for host plants (excluding saccharin or its salts).
Examples of the P group (resistance inducers in host plants) include resistance inducers that stimulate the salicylic acid pathway, resistance inducers in host plants, plant extracts that induce resistance in host plants, microorganisms and microbial preparations that induce resistance in host plants, etc. Note that the host plant resistance inducers do not include saccharin or its salts.

Group P1: Resistance inducers that stimulate the salicylic acid pathway (FRAC group code P1)
Examples of resistance inducers that stimulate the salicylic acid pathway (salicylic acid signaling) include benzothiadiazoles (BTHs) such as acibenzolar-S-methyl.

Group P2: Host plant resistance inducers (FRAC group code P2)
Examples of host plant resistance inducers (salicylic acid signaling) include benzoisothiazoles such as probenazole.
Group P3: Host plant resistance inducers (FRAC group code P3)
Examples of host plant resistance inducers (salicylic acid signaling) include thiadiazole carboxamides such as thiadinil and isothianil.

Group P4: Host plant resistance inducers (FRAC group code P4)
Examples of host plant resistance inducers (polysaccharide elicitors, natural products) include polysaccharides such as laminarin.
Group P5: Plant extracts that induce resistance in host plants (FRAC Group Code P5)
Examples of plant extracts (anthraquinone elicitors, plant extracts) that induce resistance in a host plant include mixtures of Knotweed extracts, ethanol extracts (anthraquinones, resveratrol), and the like.
Group P6: Microorganisms and microbial preparations inducing resistance in host plants (FRAC Group Code P6)
Examples of microorganisms and microbial preparations (microbial elicitors, microorganisms) that induce resistance in a host plant include bacteria of the genus Bacillus, such as Bacillus mycoides isolate J, and fungi of the genus Saccharomyces, such as the cell wall of Saccharomyces cerevisiae LAS117 strain.

Group P7: Host plant resistance inducers (FRAC group code P7)
Examples of host plant resistance inducers (phosphonates) include ethyl phosphonates such as fosetyl, phosphorous acid and salts.
Group P8: Host plant resistance inducers (FRAC group code P8)
Examples of host plant resistance inducers (salicylic acid signaling) include isothiazolyl methyl ethers such as dichlobentiazox.

(c39) Compounds with unknown mode of action (U) (FRAC group codes 27, 34, 35, 36, 37, U6, U12, U13, U14, U16, U17, U18)
Compounds with an unknown mode of action (group: unknown mode of action) include cyanoacetamide oximes such as cymoxanil; phthalamic acids such as teclofthalam; benzotriazines such as triazoxide; benzenesulfonamides such as flusulfamide; pyridazinones such as diclomezine; phenylacetamides such as cyflufenamide; guanidines such as guanidine (dodine); cyanomethylene thiazolidines such as fluthianil; pyrimidinone hydrazones such as ferimzone; 4-quinolylacetic acid such as tebufloquin; tetrazolyl oximes such as picarbutrazox; and glucopyranosyl antibiotics such as validamycin.

M Group
(c40) Multi-site contact active compound (M)
Examples of the multi-site contact-active compound (M) include inorganic compounds (electrophiles), dithiocarbamate compounds and analogues (electrophiles), phthalimides (electrophiles), chloronitriles (phthalonitriles) (site of action unknown), bisguanidines (cell membrane disruptors, surfactants), triazines, quinones (anthraquinones) (electrophiles), quinoxalines (electrophiles), maleimides (electrophiles), sulfamides, thiocarbamates, etc. Preferred examples of the multi-site contact-active compound (M) include inorganic compounds (electrophiles), chloronitriles (phthalonitriles) (site of action unknown) and bisguanidines (cell membrane disruptors, surfactants).

Inorganic compounds (electrophiles) (FRAC group codes M1, M2)
Examples of inorganic compounds (electrophiles) include copper compounds and sulfur-based compounds.
Examples of copper compounds include copper, DBEDC, basic copper chloride, basic copper sulfate, copper hydroxide, copper nonylphenol sulfonate, and the like.
Examples of sulfur-based compounds include sulfur and lime sulfur.

Dithiocarbamates and Analogues (Electrophiles) (FRAC Group Code M3)
Examples of dithiocarbamates and analogs (electrophiles) include dithiocarbamates and analogs such as amobam, ferbam, mancozeb, maneb, metiram, propineb, thiuram, zinc thiazole, zineb, and ziram.

Phthalimides (electrophiles) (FRAC group code M4)
Examples of phthalimide compounds (electrophiles) include phthalimides such as captan, captafol, and folpet.

Chloronitriles (phthalonitriles) (site of action unknown) (FRAC group code M5)
Examples of chloronitrile (phthalonitrile) compounds include chloronitriles (phthalonitriles) such as chlorothalonil (TPN).

Sulfamides (FRAC group code M6)
Examples of the sulfamides include sulfamine-based (dichlofluanid), tolylfluanid, and the like.

Bisguanidines (cell membrane disruptors, surfactants) (FRAC group code M7)
Examples of bisguanidines include guazatine, iminoctadine acetate, iminoctadine albesilate (iminoctadine), and the like.
Triazines (FRAC group code M8)
Examples of triazines include anilazine and the like.

Quinones (anthraquinones) (electrophiles) (FRAC group code M9)
Examples of quinones (anthraquinones) (electrophiles) include quinones (anthraquinones) such as dithianon.

Quinoxalines (electrophiles) (FRAC group code M10)
Examples of quinoxalines (electrophiles) include quinoxalines such as quinoxaline-based (quinomethionate) compounds.

Maleimide (electrophile) (FRAC group code M11)
Examples of maleimides (electrophiles) include maleimides such as fluoroimide.
Thiocarbamate (FRAC group code M12)
Examples of thiocarbamates include thiocarbamates such as methasulfocarb.

BM Group
(c41) Biological control agents with multiple modes of action: plant extracts (BM) (FRAC group code BM1)
Biological controls with multiple modes of action: plant extracts include polypeptides (lectins) such as extracts from cotyledons of lupin seedlings; phanols, sesquiterpenes, triterpenoids, coumarins, etc., such as extracts from Swinglea glutunosa; extracts of Melaleuca alternifolia (tea tree oil), vegetable oils (mixtures), terpene hydrocarbons such as eugenol, geraniol, thymol, terpene alcohols and terpene phenols.

[Correction under Rule 91 25.04.2025]
(C) The fungicidal compound is preferably
(c1) RNA polymerase I inhibitors,
(c2) DNA/RNA biosynthesis inhibitors,
(c3) DNA topoisomerase type II (gyrase) inhibitors,
(c4) dihydroorotate dehydrogenase inhibitors in de novo pyrimidine biosynthesis,
(c5) tubulin polymerization inhibitors,
(c6) cell division (unknown site of action) inhibitor,
(c10) complex II (succinate dehydrogenase) inhibitors,
(c11) complex III (ubiquinol oxidase Qo site) inhibitors,
(c12) complex III (ubiquinone reductase Qi site) inhibitors,
(c16) protein biosynthesis (ribosome translation initiation step) inhibitors,
(c17) protein biosynthesis (ribosome polypeptide elongation step) inhibitors,
(c20) phospholipid biosynthesis, methyltransferase inhibitors,
(c24) a C14 demethylase inhibitor in sterol biosynthesis,
(c27) chitin biosynthetic enzyme inhibitors,
(c29) melanin biosynthesis reductase inhibitors,
(c31) polyketamide synthase inhibitors in melanin biosynthesis,
(c32) resistance inducers for host plants (excluding saccharin or its salts),
(c33) compounds with unknown mechanism of action,
(c34) at least one compound selected from the group consisting of multisite contact active compounds, and (c35) quinofumelin.

Among these, preferred fungicidal compounds are polyoxin compounds, kasugamycin, validamycin, streptomycin and oxytetracycline.
The polyoxin compound is an antibiotic, and the polyoxin compound is not particularly limited, and the chemical structures of main polyoxin compounds are described, for example, in "THE MERCK INDEX TWELFTH EDITION", page 1306. Specifically, preferred polyoxin compounds include polyoxin, polyoxin salts, polyoxin complexes, and the like.
Examples of polyoxins include polyoxin A, polyoxin B, polyoxin D, polyoxin E, polyoxin F, polyoxin G, polyoxin H, polyoxin J, polyoxin K, polyoxin L, polyoxin M, polyoxin N, and polyoxin O.
The type of polyoxin salt is not particularly limited, and examples thereof include metal salts such as zinc salts, iron salts, and titanium salts.
An example of the polyoxin complex is a complex component mainly composed of polyoxin B.
The polyoxin compound may be used alone or in combination of two or more kinds. A compound containing two or more kinds of polyoxins may be called a polyoxin complex.
Currently, there are two known active ingredients registered as pesticides in Japan: polyoxin complex (a complex component whose main component is polyoxin B) and polyoxin D zinc salt (a zinc salt whose main component is polyoxin D).
Preferred polyoxin compounds are polyoxin complex and polyoxin D zinc salt.

In the present disclosure, (C) the bactericidal active compound is typically mixed in an amount of 0.1 to 20,000 parts by mass, preferably 1 to 10,000 parts by mass, and more preferably 5 to 5,000 parts by mass per 100 parts by mass of (A) saccharin and/or its salt.

The composition of the present disclosure may contain suitable auxiliary ingredients in addition to (A) saccharin and/or a salt thereof, (B) the insecticidal active compound, and (C) the fungicidal active compound.
By including, as the auxiliary component, an auxiliary agent such as a water-insoluble inorganic substance, for example, talc, rosewood, or silica, it is possible to prevent caking during production of the composition of the present disclosure.

The disclosed composition can also be mixed or used in combination with at least one optional component selected from the group consisting of other fungicides, insecticides, herbicides, plant growth regulators, microbial materials, mollusc control agents, and bird pest control agents, to the extent that the effect of the disclosed composition is not impaired. The microbial materials are microorganisms that have a control effect against harmful organisms (e.g., insecticidal activity, fungicidal activity, herbicidal activity, etc.) and/or a plant growth regulating effect such as rhizobia and mycorrhizal fungi.

The composition of the present disclosure may contain metaldehyde, which is a molluscicide, in addition to (A) saccharin and/or its salt, (B) insecticidal compound, and (C) fungicidal compound. Alternatively, the composition of the present disclosure and metaldehyde can be applied simultaneously or at different times during the cultivation period. In this case, harmful mollusks such as apple snails and lymnaea can be controlled.
Other mollusc control agents include bis(tributyltin)oxide, allicin, bromoacetamide, cloethocarb, copper sulfate, fentin, ferric phosphate, methiocarb, niclosamide, pentachlorophenol, sodium pentachlorophenoxide, sodium pentachlorophenoxide, tazimcarb, thiacloprid, thiodicarb, tralopyril, trifenmorph, trimethacarb, cartap, and bensultap.

The composition of the present disclosure may contain anthraquinone, which is a bird repellent, in addition to (A) saccharin and/or its salt, (B) insecticidal active compound, and (C) fungicidal active compound. Alternatively, the composition of the present disclosure and anthraquinone may be applied simultaneously or at different times during the cultivation period. In this case, damage caused by birds in the cultivation of plants other than rice can be suppressed.
Other bird pest control agents include chloralose, basic copperoxychloride, diazinon, guazatine, methiocarb, thiram, trimethacarb, ziram, zinc oxide, and the like.

The composition of the present disclosure may contain a herbicide and/or a safener in addition to (A) saccharin and/or its salt, (B) an insecticidal compound, and (C) a fungicidal compound. Alternatively, the composition of the present disclosure and the herbicide and/or the safener may be applied simultaneously or at different times during the cultivation period. In this case, weeds in the cultivation of plants other than rice can be controlled.
Examples of the safeners include AD-67, BAS-145138, benoxacor, cloquintocet-mexyl, cyometrinil, 2,4-D, DKA-24, dichlormid, dymron, fenclorim, fenchlorazole-ethyl, flurazole, fluxofenim, furilazole, isoxadifen-ethyl, mefenpyr-diethyl, MG-191, naphthalic anhydride, oxabetrinil, PPG-1292, and R-29148.

Method for producing agricultural and horticultural pest control composition The composition disclosed herein need only contain (A) saccharin and/or a salt thereof, (B) an insecticidally active compound, and (C) a fungicidal compound without adding any other ingredients. Generally, however, it is preferable to mix a solid carrier, a liquid carrier, or a gaseous carrier (propellant), add a surfactant or other formulation adjuvants as necessary, and formulate the composition into an oil solution, emulsion, wettable powder, flowable agent, granules, powder, aerosol, fog, or the like according to a conventional formulation method for use.

These preparations contain the active ingredients (A) saccharin and/or its salt, (B) insecticidal compound, and/or (C) fungicidal compound in a total weight ratio of usually 0.01 to 95% by mass, preferably 0.05 to 80% by mass, and more preferably 0.1 to 70% by mass.

Solid carriers used in formulation include, for example, fine powders or granules of clays (kaolin clay, diatomaceous earth, synthetic hydrous silicon oxide, bentonite, fubasami clay, acid clay, etc.), talcs, ceramics, other inorganic minerals (celite, quartz, sulfur, activated carbon, calcium carbonate, hydrated silica, etc.), and chemical fertilizers (ammonium sulfate, ammonium phosphate, ammonium nitrate, urea, ammonium chloride, etc.).

Liquid carriers include, for example, water, alcohols (methanol, ethanol, etc.), ketones (acetone, methyl ethyl ketone, etc.), aromatic hydrocarbons (benzene, toluene, xylene, ethylbenzene, methylnaphthalene, etc.), aliphatic hydrocarbons (hexane, cyclohexane, kerosene, diesel, etc.), esters (ethyl acetate, butyl acetate, etc.), nitriles (acetonitrile, isobutyronitrile, etc.), ethers (diisopropyl ether, dioxane, etc.), acid amides (N,N-dimethylformamide, N,N-dimethylacetamide, etc.), halogenated hydrocarbons (dichloromethane, trichloroethane, carbon tetrachloride, etc.), dimethyl sulfoxide, vegetable oils such as soybean oil and cottonseed oil, etc.

Examples of gaseous carriers include butane gas, LPG (liquefied petroleum gas), dimethyl ether, carbon dioxide gas, etc.

Surfactants include, for example, alkyl sulfates, alkyl sulfonates, alkylaryl sulfonates, alkylaryl ethers and their polyoxyethylated derivatives, polyethylene glycol ethers, polyhydric alcohol esters, sugar alcohol derivatives, etc.

Examples of formulation adjuvants include adhesives, dispersants, stabilizers, etc.

Examples of adhesives or dispersants include casein, gelatin, polysaccharides (starch powder, gum arabic, cellulose derivatives, alginic acid, etc.), lignin derivatives, bentonite, sugars, and synthetic water-soluble polymers (polyvinyl alcohol, polyvinylpyrrolidone, polyacrylic acids, etc.). Examples of stabilizers include PAP (isopropyl acid phosphate), BHT (2,6-di-tert-butyl-4-methylphenol), BHA (a mixture of 2-tert-butyl-4-methoxyphenol and 3-tert-butyl-4-methoxyphenol), vegetable oils, mineral oils, fatty acids or their esters, etc.

The disclosed composition may be used as is or diluted with water or the like. It may also be used in combination with other insecticides, fungicides, herbicides, plant growth regulators, synergists, soil conditioners, animal feed, etc., or may be used without mixing.

When the composition of the present disclosure contains two components, namely, the component (A) and the component (B), or the component (A) and the component (C), the total amount thereof can generally be 0.01 to 95 mass%, preferably 0.05 to 80 mass%, and more preferably 0.1 to 50 mass%.
When the three components, component (A), component (B), and component (C), are blended, the total amount of components (A), (B), and (C) can generally be 0.01 to 95 mass%, preferably 0.05 to 80 mass%, and more preferably 0.1 to 70 mass%.

The application amount of the composition of the present disclosure is usually from 0.05 g to 600 g, preferably from 0.1 to 200 g, and more preferably from 0.5 to 100 g per 1 a (100 m ² ).
When the synergistic insecticide composition of the present disclosure in the form of an emulsifiable concentrate, wettable powder, flowable agent, liquid agent or the like is used by diluting with water, the application concentration is usually 0.1 to 300,000 ppm, preferably 1 to 30,000 ppm, more preferably 10 to 8,000 ppm.
In this case, the application concentration of the (A) component is usually 0.05 to 150,000 ppm, preferably 0.5 to 10,000 ppm, more preferably 5 to 4,000 ppm. The application concentration of the (B) component is usually 0.05 to 150,000 ppm, preferably 0.5 to 10,000 ppm, more preferably 5 to 4,000 ppm. The application concentration of the (C) component is usually 0.05 to 150,000 ppm, preferably 0.5 to 10,000 ppm, more preferably 5 to 4,000 ppm.
For example, in the case of normal spraying, the application concentration of the composition of the present disclosure is usually 0.1 to 10,000 ppm, preferably 1 to 5,000 ppm, and more preferably 10 to 1,000 ppm.
In the case of drenching, the application concentration of the composition of the present disclosure is usually 1 to 300,000 ppm, preferably 10 to 30,000 ppm, and more preferably 100 to 8,000 ppm.
Granules, dusts and the like are applied as they are without being diluted with water.

These application amounts and concentrations vary depending on the type of formulation, application time, application location, application method, type of pest, level of damage, and other conditions, and can be increased or decreased without being limited to the above ranges.

Pests that can be controlled by the disclosed composition include, for example, pests such as insects, mites, nematodes, and mollusks; and plant pathogens such as mold, bacteria, and viruses.

Specific examples of insects, mites, nematodes, mollusks, etc. that can be controlled by the disclosed composition include the following:

Insects Hemiptera: Laodelphax striatellus, Nilaparvata lugens, Sogatella furcifera, Peregrinus maidis, Javesella pellucida, Perkinsiella saccharicida, Tagosodes orizicolus and other Delphacidae; Nephotettix cincticeps, Nephotettix virescens, Nephotettix nigropictus, Recilia dorsalis, Empoasca onukii, Empoasca fabae), Dalbulus maidis, Cofana spectra, and other Cicadellidae; Mahanarva posticata, Mahanarva fimbriolata, and other Cercopidae; Aphis fabae, Aphis glycines, Aphis gossypii, Aphis pomi, Aphis spiraecola, Myzus persicae, Brachycaudus helichrysi, Brevicoryne brassicae, Dysaphis plantaginea, Lipaphis fimbriolata, and other pea aphids; Aphididae such as Macrosiphum euphorbiae, Aulacorthum solani, Nasonovia ribisnigri, Rhopalosiphum padi, Rhopalosiphum maidis, Toxoptera citricida, Hyalopterus pruni, Melanaphis sacchari, Tetraneura nigriabdominalis, Ceratovacuna lanigera, Eriosoma lanigerum; Phylloxeridae, such as phylloxera (Phylloxera devastatrix), pecan leaf phylloxera (Phylloxera notabilis), and southern pecan leaf phylloxera (Phylloxera russellae); Adelgidae, such as Adelges tsugae, Adelges piceae, and Aphrastasia pectinatae; Scotinophara lurida, Malayan rice black bug (Scotinophara coarctata), Nezara antennata, Eysarcoris aeneus, Eysarcoris lewisi, and Eysarcoris Pentatomidae, such as Eysarcoris ventralis, Eysarcoris annamita, Halyomorpha halys, Nezara viridula, Euschistus heros, Piezodorus guildinii, Oebalus pugnax, and Dichelops melacanthus; Cydnidae, such as Scaptocoris castanea; Alydidae, such as Riptortus pedestris, Leptocorisa chinensis, and Leptocorisa acuta; Cletus punctiger, Leptoglossus australis, and other Coreidae; Caverelius saccharivorus, Togo hemipterus, Blissus leucopterus, and other Lygaeidae; Trigonotylus caelestialium, Stenotus rubrovittatus, Stenodema calcarata, Lygus lineolaris, and other Miridae; Trialeurodes vaporariorum, Bemisia tabaci, and other whiteflies; tabaci), Dialeurodes citri, Aleurocanthus spiniferus, Aleurocanthus camelliae, Pealius euryae, and other whiteflies; Abgrallaspis cyanophylli, Aonidiella aurantii, Diaspidiotus perniciosus, Pseudaulacaspis pentagona, Unaspis yanonensis, Unaspis citri, and other scale insects; Ceroplastes rubens; Coccidae such as Icerya purchasi and Icerya seychellarum; Phenacoccus solani, Phenacoccus solenopsis, Planococcus kraunhiae, Pseudococcus comstocki, Planococcus citri, Pseudococcus calceolariae, Pseudococcus longispinus, Brevennia rehi and other mealybugs (Pseudococcidae); Diaphorina citri, Trioza erytreae, Cacopsylla pyrisuga, Cacopsylla chinensis, Bactericera cockerelli, and Cacopsylla pyricola and other Psyllidae; Corythucha ciliata, Corythucha marmorata, Stephanitis nashi, and Stephanitis pyrioides and other Tingidae; Cimex lectularius and other bedbugs; Giant bedbugs; Cicada family (Cicadidae), including Cicada (Quesada gigas).

Lepidoptera: Chilo suppressalis, Darkheaded stem borer, Chilo polychrysus, White stem borer, Scirpophaga innotata, Scirpophaga incertulas, Rupela albina, Cnaphalocrocis medinalis, Marasmia patnalis, Marasmia exigua, Notarcha derogata, Ostrinia furnacalis, European corn borer, Ostrinia nubilalis, Haplopod moth, Crambidae, such as the Japanese rice leaf moth (Hellula undalis), the black rice leaf moth (Herpetogramma luctuosale), the lawn moth (Pediasia teterrellus), the rice case worm (Nymphula depunctalis), and the sugarcane borer (Diatraea saccharalis); Pyralidae, such as the corn meal moth (Elasmopalpus lignosellus) and the Indian meal moth (Plodia interpunctella); Spodoptera litura, Spodoptera exigua, Mythimna separata, Armyworm moth (Mamestra brassicae), Rice armyworm moth (Sesamia inferens), Armyworm moth (Spodoptera mauritia), Two-banded cutworm moth (Naranga aenescens), Spodoptera frugiperda, African armyworm moth (Spodoptera exempta), Cutworm moth (Agrotis ipsilon), Silver looper moth (Autographa nigrisigna), Rice yellow looper moth (Plusia festucae), Soybean looper (Chrysodeixis includens), Trichoplusia spp., False tobacco budworm (Heliothis virescens) ), Heliothis spp. such as Helicoverpa armigera and Helicoverpa zea, Noctuidae such as Velvetbean caterpillar (Anticarsia gemmatalis), Cotton leafworm (Alabama argillacea), and Hop vine borer (Hydraecia immanis); Pieridae such as Pieris rapae; Pear fruit moth (Grapholita molesta), Plum fruit moth (Grapholita dimorpha), and Bean cicada moth (Grapholita geranium). The Tortricidae family, including the grass moth (Leguminivora glycinivorella), the bean pea moth (Matsumuraeses azukivora), the apple tortrix moth (Adoxophyes orana fasciata), the tea tortrix moth (Adoxophyes honmai), the tea tortrix moth (Homona magnima), the green tea tortrix moth (Archips fuscocupreanus), the codling moth (Cydia pomonella), the bean shoot borer (Tetramoera schistaceana), the bean shoot borer (Epinotia aporema), and the citrus fruit borer (Ecdytolopha aurantiana), are also active. icidae); Gracilariidae such as the tea leaf moth (Caloptilia theivora) and the golden leaf moth (Phyllonorycter ringoniella); Carposinidae such as the peach fruit moth (Carposina sasakii); Lyonetiidae such as the coffee leaf miner (Leucoptera coffee), the peach leafminer (Lyonetia clerkella), and the golden leafminer (Lyonetia prunifoliella); Lymantria spp. such as the gypsy moth (Lymantria dispar), and the brown tussock moth (Euproctis pseudoconspers a) and other Euproctis spp.; Plutellidae such as Plutella xylostella; Gelechiidae such as Anarsia lineatella, Helcystogramma triannulella, Pectinophora gossypiella, Phthorimaea operculella, and Tuta absoluta; Arctiidae such as Hyphantria cunea; Castanopsis moths such as the Giant Sugarcane borer Telchin licus family (Castniidae); Cossidae such as Cossus insularis; Geometridae such as Ascotis selenaria; Limacodidae such as Parasa lepida; Stathmopodidae such as Stathmopoda masinissa; Sphingidae such as Acherontia lachesis; Sesiidae such as Nokona feralis; Hesperiidae such as Parnara guttata.

Thysanoptera: Thripidae, such as Frankliniella occidentalis, Thrips palmi, Scirtothrips dorsalis, Thrips tabaci, Frankliniella intonsa, Stenchaetothrips biformis, Echinothrips americanus; Phlaeothripidae, such as Haplothrips aculeatus.

Diptera: Anthomyiidae such as Delia platura, Delia antiqua, Pegomya cunicularia; Ulidiidae such as Tetanops myopaeformis; Agromyzidae such as Agromyza oryzae, Liriomyza sativae, Liriomyza trifolii, Chromatomyia horticola; Chloropidae such as Chlorops oryzae; Bactrocera cucurbitae, Oriental fruit fly; The Tephritidae family includes Bactrocera dorsalis, Bactrocera latifrons, Bactrocera oleae, Bactrocera tryoni, Ceratitis capitata, Rhagoletis pomonella, and Rhacochlaena japonica; the Ephydridae family includes Hydrellia griseola, Hydrellia philippina, and Hydrellia sasakii; the Drosophila suzukii family includes Drosophila suzukii, ... philidae); Phoridae, such as the giant fruit fly (Megaselia spiracularis); Psychodidae, such as the large butterfly fly (Clogmia albipunctata); Sciaridae, such as the little black fungus fly (Bradysia difformis); Cecidomyiidae, such as the Hessian fly (Mayetioladestructor) and the rice gall fly (Orseolia oryzae); Diopsidae, such as Diopsis macrophthalma; Crane flies, such as Tipula aino, the common cranefly (Tipula oleracea), and the European cranefly (Tipula paludosa). ipulidae), Culex pipiens pallens, Aedes aegypti, Aedes albopicutus, Anopheles hyracanus sinesis, Culex quinquefasciatus, Culex pipiens molestus Forskal, and other mosquitoes; Simulidae, such as Prosimulium yezoensis and Simulium ornatum; Tabanidae, such as Tabanus trigonus; Musca domestica, Muscina stabulans, and other house flies; Muscidae, etc.

Coleoptera: Western corn rootworm (Diabrotica virgifera virgifera), Southern corn rootworm (Diabrotica undecimpunctata howardi), Northern corn rootworm (Diabrotica barberi), Mexican corn rootworm (Diabroticavirgifera zeae), Banded cucumber beetle (Diabrotica balteata), Cucurbit beetle (Diabrotica speciosa), Bean leaf beetle (Cerotoma trifurcata), Red-necked leaf beetle (Oulema melanopus), Cucumber leaf beetle (Aulacophora femoralis), Striped flea beetle (Phyllotreta striolata), Cabbage flea beetle (Phyllotreta cruciferae), Western black flea beetle (Phyllotreta pusilla), Cabbage stem fleabeetle (Psylliodes chrysocephala), hop flea beetle (Psylliodes punctulata), Colorado beetle (Leptinotarsa decemlineata), rice leaf beetle (Oulema oryzae), grape colaspis (Colaspis brunnea), corn flare beetle (Chaetocnema pulicaria), sweet potato stag beetle (Chaetocnema confinis), potato flare beetle (Epitrix cucumeris), rice spur beetle (Dicladispa armigera), southern corn leaf beetle (Myochrous denticollis), four-legged tortoise beetle (Laccoptera quadrimaculata), tobacco flea beetle (Epitrix hirtipennis), etc. from the Chrysomelidae family; seedcorn beetle (Stenolophus lecontei), slender seedcorn beetle (Clivina impressifrons and other beetles; Scarabaeidae such as Anomala cuprea, Anomala rufocuprea, Anomala albopilosa, Popillia japonica, Heptophylla picea, Rhizotrogus majalis, Tomarus gibbosus, Holotrichia spp., Phyllophaga spp. such as Phyllophaga crinita, and Diloboderus spp. such as Diloboderus abderus; formicarius), potato weevil (Euscepes postfasciatus), alfalfa weevil (Hypera postica), maize weevil (Sitophilus zeamais), rice weevil (Echinocnemus squameus), rice water weevil (Lissorhoptrus oryzophilus), white-spotted weevil (Rhabdoscelus lineatocollis), boll weevil (Anthonomus grandis), grass striped weevil (Sphenophorus venatus), Southern Corn Billbug (Sphenophorus callosus), soybean stalk weevil (Sternechus subsignatus), sugarcane weevil (Sphenophorus levis), rust gourd weevil (Scepticus griseus), brown gourd weevil (Scepticus uniformis), Brazilian bean weevil (Zabrotes subfasciatus), Aracanthus spp. such as Tomicus piniperda, Coffee Berry Borer (Hypothenemushampei), Aracanthus mourei, and other Aracanthus spp., and cotton root borer (Eutinobothrus brasiliensis) from the Curculionidae family; Tenebrionidae such as Tribolium castaneum and Tribolium confusum from the Tenebrionidae family; Coccinellidae such as Epilachna vigintioctopunctata; Bostrychidae such as Lyctus brunneus; Ptinidae; Anoplophora Cerambycidae, such as Migdolus malasiaca and Migdolus fryanus;
Elateridae family such as Melanotus okinawensis, Agriotes fuscicollis, Melanotus legatus, Anchastus spp., Conoderus spp., Ctenicera spp., Limonius spp., Aeolus spp., etc.; Staphylinidae family such as Paederus fuscipes.

Orthoptera: Migratory grasshopper (Locusta migratoria), Moroccan grasshopper (Dociostaurus maroccanus), Australian grasshopper (Chortoicetes terminifera), Red grasshopper (Nomadacris septemfasciata), Brown Locust (Locustana pardalina), Tree Locust (Anacridium melanorhodon), Italian Locust (Calliptamus italicus), Differential grasshopper (Melanoplus differentialis), Two striped grasshopper (Melanoplus bivittatus), Migratory grasshopper (Melanoplus sanguinipes), Red-Legged grasshopper (Melanoplus fetus) murrubrum), Clearwinged grassshopper (Camnula pellucida), Desert grasshopper (Schistocerca gregaria), Yellow-winged locust (Gastrimargus musicus), Spur-throated locust (Austracris guttulosa), Oriental grasshopper (Oxya yezoensis), Long-winged locust (Oxya japonica), Thailand The grasshopper family (Acrididae) includes the Japanese grasshopper (Patanga succincta); the mole cricket family (Gryllotalpidae) includes the mole cricket (Gryllotalpa orientalis); the field cricket family (Gryllidae) includes the European house cricket (Acheta domestica) and the field cricket (Teleogryllus emma); and the katydid family (Tettigoniidae) includes the mormon cricket (Anabrus simplex).

Hymenoptera: Tenthredinidae, such as Athalia rosae and Athalia japonica; Formicidae, such as Solenopsis spp. and Brown leaf-cutting ant Atta capiguara.

　Order Blattodea: Family Blattellidae such as the German cockroach (Blattella germanica); Family Blattidae such as the American cockroach (Periplaneta fuliginosa), American cockroach (Periplaneta americana), Brown cockroach (Periplaneta brunnea), and Asian cockroach (Blatta orientalis); Family Reticulitermes speratus, Formosan termite (Coptotermes formosanus), American dry wood termite (Incisitermes minor), Formosan termite (Cryptotermes domesticus), Formosan termite (Odontotermes formosanus), Chinese termite (Neotermes koshunensis), Satsuma termite (Odontotermes formosanus), Japanese termite (Neotermes koshunensis), and Japanese termite (Odontotermes formosanus). Termites from the Termitidae family, including Glyptotermes satsumensis, Glyptotermes nakajimai, Glyptotermes fuscus, Hodotermopsis sjostedti, Coptotermes guangzhouensis, Reticulitermes amamianus, Reticulitermes miyatakei, Reticulitermes kanmonensis, Nasutitermes takasagoensis, Pericapritermes nitobei, Sinocapritermes mushae, and Cornitermes cumulans.

Acari: Tetranychidae , such as Tetranychus urticae, Tetranychus kanzawai, Tetranychus evansi, Panonychus citri, Panonychus ulmi, and Oligonychus spp.; Aculops pelekassi, Phyllocoptruta citri, Aculops lycopersici, Calacarus carinatus, Acaphylla theavagrans, Eriophyes chibaensis, Aculus schlechtendali, and Aceria diospyri, Aceria tosichella, Shevtchenkella sp. and other Eriophyidae; Tarsonemidae such as Polyphagotarsonemuslatus; Tenuipalpidae such as Brevipalpus phoenicis; Tuckerellidae; Haemaphysalis longicornis, Haemaphysalis flava, Dermacentor taiwanensis, Dermacentor variabilis, Ixodes ovatus, Ixodes persulcatus, Ixodes scapularis, Amblyomma americanum, Boophilus microplus, Rhipicephalus sanguineus, and other ticks; Acaridae, Tyrophagus putrescentiae, Tyrophagus similis, and other ticks; Pyroglyphidae, Dermatophagoides farinae, Dermatophagoides pteronyssinus, and other ticks; Cheyletidae, Cheyletus eruditus, Cheyletus malaccensis, Cheyletus moorei, Cheyletiella yasguri, and other ticks; Otodectes cynotis, Sarcoptes scabiei, and other Sarcoptidae; Demodex canis, and other Demodex mites; Listrophoridae; Haplochthoniidae; Macronyssidae, Ornithonyssus bacoti, Ornithonyssus sylviarum, and other Macronyssidae; Dermanyssidae, Dermanyssus gallinae, and other Dermanyssus gallinae; Trombiculidae, Leptotrombidium akamushi, and other Trombiculidae.

Nematodes Nematoda : Aphelenchoididae such as Aphelenchoides besseyi; Pratylenchidae such as Pratylenchus coffeae, Pratylenchus brachyurus, Pratylenchus neglectus, Radopholus similis; Meloidogyne javanica, Meloidogyne incognita, Meloidogyne hapla, Heterodera glycines, Globodera rostochiensis, Globodera similis, Meloidogyne spp. Heteroderidae such as Rotylenchulus reniformis; Hoplolaimidae such as Rotylenchulus reniformis; Anguinidae such as Nothotylenchus acris and Ditylenchus dipsaci; Tylenchulidae such as Tylenchulus semipenetrans; Longidoridae such as Xiphinema index; Trichodoridae;
Parasitaphelenchidae, such as the pinewood nematode (Bursaphelenchus xylophilus).

Class Gastropoda ( Mollusca ): Family Limacidae such as Limax marginatus and Limax flavus; Family Philomycidae such as Meghimatium bilineatum; Family Ampullariidae such as Pomacea canaliculata; Family Lymnaeidae such as Austropeplea ollula; etc.

Specific examples of plant diseases caused by plant pathogens that can be controlled by the composition of the present disclosure include the following. The names in parentheses indicate the scientific names of the plant pathogens that cause each disease.
Plant diseases (plant pathogens)
Wheat diseases: powdery mildew (Erysiphe graminis), red mold (Fusarium graminearum, F. avenacerum, F. culmorum, Microdochium nivale), rust (Puccinia striiformis, P. graminis, P. recondita), pink snow mold (Micronectriella nivale), snow mold sclerotinia (Typhula sp.), bare smut (Ustilago tritici), cattail smut (Tilletia caries), eyespot (Pseudocercosporella herpotrichoides), leaf blight (Mycosphaerella graminicola), leaf spot (Stagonospora nodorum), yellow spot (Pyrenophora tritici-repentis), etc.
Barley diseases: powdery mildew (Erysiphe graminis), red mold (Fusarium graminearum, F. avenacerum, F. culmorum, Microdochium nivale), rust (Puccinia striiformis, P. graminis, P. hordei), naked smut (Ustilago nuda), scald (Ustilago nuda), net blotch (Pyrenophora teres), leaf spot (Cochliobolus sativus), leaf spot (Pyrenophora graminea), seedling damping-off caused by Rhizoctonia genus fungi (Rhizoctonia solani), etc.
Corn diseases: ear smut (Ustilago maydis), brown spot (Cochliobolus heterostrophus), hail blight (Gloeocercospora sorghi), southern rust (Puccinia polysora), gray leaf spot (Cercospora zeae-maydis), seedling damping-off caused by Rhizoctonia genus fungi (Rhizoctonia solani), etc.

Citrus diseases: black spot (Diaporthe citri), scab (Elsinoe fawcetti),
Fruit rot diseases (Penicillium digitatum, P. italicum), Phytophthora diseases (Phytophthora parasitica, Phytophthora citrophthora), etc.
Apple diseases: Monilinia mali, Valsa ceratosperma, powdery mildew (Podosphaera leucotricha), leaf spot (Podosphaera leucotricha), black spot (Venturia inaequalis), anthracnose (Colletotrichum acutatum), late blight (Phytophtora cactorum), etc.
Pear diseases: black spot (Venturia nashicola, V. pirina), black spot (Alternaria alternata Japanese pear pathotype), red spot (Gymnosporangium haraeanum), late blight (Phytophtora cactorum), etc.
Peach diseases: Brown spot (Monilinia fructicola), black spot (Cladosporium carpophilum), Phomopsis rot (Phomopsis sp.), etc.
Grape diseases: black rot (Elsinoe ampelina), late rot (Glomerella cingulata), powdery mildew (Uncinula necator), rust (Phakopsora ampelopsidis), black rot (Guignardia bidwellii), downy mildew (Plasmopara viticola), etc.
Persimmon diseases: Anthracnose (Gloeosporium kaki), leaf spot (Cercospora kaki, Mycosphaerella nawae), etc.
Diseases of cucurbits: anthracnose (Colletotrichum lagenarium), powdery mildew (Sphaerotheca fuliginea), vine wilt (Mycosphaerella melonis), vine splitting (Fusarium oxysporum), downy mildew (Pseudoperonospora cubensis), late blight (Phytophthora sp.), seedling damping-off (Pythium sp.), and the like.
Tomato diseases: ring spot (Alternaria solani), leaf mold (Cladosporium fulvum), late blight (Phytophthora infestans).
Eggplant diseases: Brown spot (Phomopsis vexans), powdery mildew (Erysiphe cichoracearum), etc.
Diseases of cruciferous vegetables: black spot (Alternaria japonica), white spot (Cercosporella brassicae), clubroot (Plasmodiophora brassicae), downy mildew (Peronospora parasitica), black spot bacterial disease (Pseudomonas syringae pv. maculicola and Pseudomonas cannabina pv. alisalensis), soft rot (Pectobacterium carotovora subsp. carotovora), etc.
Diseases of leeks: rust (Puccinia allii), downy mildew (Peronospora destructor), soft rot (Pectobacterium carotovora subsp. carotovora), etc.

Soybean diseases: purple spot (Cercospora kikuchii), black rot (Elsinoe glycines), black spot (Diaporthe phaseolorum var. sojae), brown spot (Septoria glycines), leaf spot (Cercospora sojina), rust (Phakopsora pachyrhizi), stem rot (Phytophthora sojae), seedling damping-off caused by Rhizoctonia solani, brown ring spot (Corynespora cassiicola), sclerotinia sclerotiorum, etc.
Diseases of beans: Anthracnose (Colletotrichum lindemuthianum), etc.
Peanut diseases: black spot (Cercospora personata), brown spot (Cercospora arachidicola), southern blight (Sclerotium rolfsii), etc.
Pea diseases: Powdery mildew (Erysiphe pisi), etc.
Potato diseases: Alternaria solani, Phytophthora infestans, Phytophthora erythroseptica, powdery scab (Spongospora subterranean f.sp. subterranea), etc.
Strawberry diseases: Powdery mildew (Sphaerotheca humuli), anthracnose (Glomerella cingulata), etc.
Tea diseases: net blight (Exobasidium reticulatum), white spot (Elsinoe leucospila), ring spot (Pestalotiopsis sp.), anthracnose (Colletotrichum theae-sinensis), etc.
Tobacco diseases: red spot (Alternaria longipes), powdery mildew (Erysiphe cichoracearum), anthracnose (Colletotrichum tabacum), downy mildew (Peronospora tabacina), late blight (Phytophthora nicotianae), etc.
Diseases of rapeseed: Sclerotinia sclerotiorum, damping-off caused by Rhizoctonia solani, etc.
Cotton diseases: Seedling damping-off (Rhizoctonia solani), white mold (Mycosphaerella areola), black root rot (Thielaviopsis basicola), etc.
Coffee diseases: Rust (Hemileia vastatrix), etc.
Sugarcane diseases: Rust (Puccinia melanocephela, Puccinia kuehnii), smut (Ustilago scitaminea), etc.
Sunflower diseases: Rust (Puccinia helianthi), etc.
Diseases of sugar beet: Cercospora beticola, leaf rot (Thanaphorus cucumeris), root rot (Thanaphorus cucumeris), black root rot (Aphanomyces cochlioides), etc.
Rose diseases: black spot (Diplocarpon rosae), powdery mildew (Sphaerotheca pannosa), downy mildew (Peronospora sparsa), etc.
Diseases of chrysanthemums and Asteraceae vegetables: downy mildew (Bremia lactucae), brown spot disease (Septoria chrysanthemi-indici), white rust (Puccinia horiana), etc.
Diseases of various plants: diseases caused by Pythium fungi (Pythium aphanidermatum, P. debarianum, P. graminicola, P. irregulare, P. ultimum), gray mold (Botrytis cinerea), sclerotinia sclerotiorum, etc.
Radish diseases: black spot (Alternaria brassicicola), etc.
Diseases of turfgrass: dollar spot disease (Sclerotinia homoeocarpa), brown patch disease, large patch disease (Rhizoctonia solani), etc.
Banana diseases: Sigatoka disease (Mycosphaerella fijiensis, Mycosphaerella musicola), etc.
Sunflower diseases: Downy mildew (Plasmopara halstedii), etc.
Seed diseases or diseases in the early growth stage of various plants caused by fungi of the genera Aspergillus, Penicillium, Fusarium, Gibberella, Tricoderma, Thielaviopsis, Rhizopus, Mucor, Corticium, Phoma, Rhizoctonia, and Diplodia.

In addition, the disclosed composition can also protect crops from viral diseases transmitted by harmful insects belonging to the Hemiptera order, such as Tomato yellow leaf curl virus, Cucumber mosaic virus and Turnip mosaic virus, Beet western yellows virus, and Cauliflower mosaic virus.

Method of Application Methods of application of the composition of the present disclosure include, for example, in the case of granules, planting hole treatment at the time of planting, treatment at the base of the plant, etc., and in the case of liquid formulations, immersion treatment, irrigation treatment before planting, irrigation treatment at the base of the plant, soil irrigation treatment, foliar spraying, aerial spraying, etc.
The composition of the present disclosure thus prepared can be applied simultaneously or in separate portions to useful plants or to the area where useful plants are to be grown or are growing, thereby controlling the growth of plants that are undesirable for the useful plants. The useful plants include field crops, horticultural crops, turf, fruit trees, non-agricultural land, etc.

The application amount and concentration of the disclosed composition can vary over a wide range depending on weather conditions, application time, application location, application method, etc., but the application amount of components (A) to (C) contained in the disclosed composition is usually about 0.05 to 600 g/a in total, preferably 0.1 to 200 g/a, and more preferably 0.5 to 100 g/a.

The present disclosure will be explained in more detail below using examples, but the technical scope of the present disclosure is not limited to these examples.

The following are formulation examples. Note that "parts" means "parts by mass." However, the formulations are not limited to those shown and can be widely varied.

Formulation Example 1 (emulsion)
10 parts of each of the compositions of the present disclosure are dissolved in 45 parts of Solvesso 150 and 35 parts of N-methylpyrrolidone, and 10 parts of an emulsifier (product name: Solpol 3005X, manufactured by Toho Chemical Industry Co., Ltd.) are added thereto and mixed with stirring to obtain 10% emulsions of each.

Formulation Example 2 (wettable powder)
20 parts of each of the compositions of the present disclosure are added to a mixture of 2 parts of sodium lauryl sulfate, 4 parts of sodium lignin sulfonate, 20 parts of synthetic hydrous silicon oxide fine powder, and 54 parts of clay, and the mixture is stirred and mixed in a juice mixer to obtain a 20% hydration agent.

Formulation Example 3 (Granules)
2 parts of sodium dodecylbenzenesulfonate, 10 parts of bentonite, and 83 parts of clay are added to 5 parts of each of the compositions of the present disclosure and thoroughly mixed. The appropriate amount of water is added, further stirred, granulated in a granulator, and dried by ventilation to obtain 5% granules.

Formulation Example 4 (Powder)
One part of each of the compositions of the present disclosure is dissolved in an appropriate amount of acetone, to which 5 parts of synthetic hydrous silicon oxide fine powder, 0.3 parts of isopropyl acid phosphate (PAP) and 93.7 parts of clay are added, and the mixture is stirred and mixed in a juice mixer. The acetone is evaporated off to obtain a 1% powder.

Formulation Example 5 (flowable formulation)
20 parts of each of the compositions of the present disclosure, 3 parts of polyoxyethylene tristyrylphenyl ether phosphate ester triethanolamine, and 20 parts of water containing 0.2 parts of Rhodorsil 426R are mixed, wet-ground using a Dyno Mill, and then mixed with 60 parts of water containing 8 parts of propylene glycol and 0.32 parts of xanthan gum to obtain a 20% suspension in water.

Formulation Example 6 (liquid)
10 parts of each of the compositions of the present disclosure, 5 parts of polyoxyethylene sorbitan monostearate, 5 parts of propylene glycol and 70 parts of water are mixed with stirring to obtain a 10% solution of each.

The effectiveness of certain combinations of particularly preferred compositions has been confirmed through biological testing.

Biological Test Example 1: Preventive Effect A chemical solution (Kumiten (registered trademark) was added at a 5,000-fold concentration) containing the compounds (A) and (C) shown in Table 1 was sprayed onto Chinese cabbage seedlings grown in 6.5 cm polypots, and the plants were air-dried. Approximately 24 hours after spraying, a suspension of Bacillus subtilis var. nigricans (containing 500 ppm Tween-20 aq.) was sprayed and inoculated, and the plants were kept in a moist room set at 25°C. After 6 days, the number of lesions was counted, and the control value was calculated from the following formula. This test was carried out in one series of 5 plants per plot.
Control value = (1 - (average number of lesions in treated area/average number of lesions in untreated area)) x 100
The results are shown in Table 1.

To indicate the degree of synergistic effect, the "control value expectation value" was calculated from the following formula based on the Colby method. When the control value is greater than each "control value expectation value", it is judged that a synergistic effect exists.
Expected value = X + Y - XY/100
X: Control value in the area where A is used alone Y: Control value in the area where C is used alone

Results As a result, the plant pest control composition containing compound (A) and compound (C) showed a synergistic effect against Chinese cabbage black spot bacterial disease when applied to the target.

Biological Test Example 2: Curative Effect Chinese cabbage seedlings grown in 6.5 cm polypots were inoculated by spraying with a suspension of Bacillus subtilis var. niger (containing 500 ppm Tween-20 aq.) and were then kept in a moist chamber set at 25° C. for one day. Approximately 24 hours after inoculation, a drug solution (containing Kumiten (registered trademark) at a 5,000-fold concentration) containing compounds (A) and (C) shown in Table 2 was sprayed on the plants, and the plants were returned to the moist chamber. After 6 days, the number of lesions was counted, and the control value was calculated from the following formula. This test was carried out in one series of 5 plants per plot.
Control value = (1 - (average number of lesions in treated area/average number of lesions in untreated area)) x 100
The results are shown in Table 2.

Results As a result, the plant pest control composition containing compound (A) and compound (C) showed a synergistic effect against Chinese cabbage black spot bacterial disease when applied to the target.

Biological Test Example 3: Preventive Effect A liquid drug (containing Kumiten (registered trademark) at a 3,300-fold concentration) containing the compounds (A) and (C) shown in Table 3 was sprayed onto cabbage seedlings grown in 6.5 cm polypots. Approximately 24 hours after spraying, a flora disk was prepared from a plate medium on which vegetable sclerotium had been previously cultured, and placed on the leaves for inoculation, followed by management in a moist chamber set at 20°C. After 3 days, the lesion diameter was measured, and the control value was calculated from the following formula. This test was carried out in one series of 5 plants per area.
Control value = (1 - (lesion spot size in treated area/lesion spot size in untreated area)) x 100
The results are shown in Table 3.

Results As a result, the plant pest control composition containing compound (A) and compound (C) showed a synergistic effect against cabbage stem rot when applied to the target.
This application claims priority from Japanese Patent Application No. 2023-185781, filed on October 30, 2023. Japanese Patent Application No. 2023-185781 is incorporated herein by reference.

Claims (8)

(A) saccharin and/or a salt thereof;
An agricultural and horticultural pest control composition (excluding pest control compositions for paddy rice) containing at least one plant treatment composition selected from the group consisting of (B) an insecticidally active compound and (C) a fungicidal compound. The agricultural and horticultural pest control composition comprises (A) saccharin and/or a salt thereof,
The agricultural and horticultural pest control composition according to claim 1 (excluding a pest control composition for paddy rice), which contains the fungicidal compound (C). The agricultural and horticultural pest control composition according to claim 2 (excluding pest control compositions for paddy rice), in which the (C) fungicidal compound is an antibiotic for agricultural chemicals. The agricultural and horticultural pest control composition according to claim 3 (excluding pest control compositions for paddy rice), wherein the agricultural antibiotic comprises at least one antibiotic selected from the group consisting of chitin synthase inhibitors, enopyranuronic acid antibiotics, hexopyranosyl antibiotics, glucopyranosyl antibiotics, tetracycline antibiotics, and amphoteric macrolide antifungal antibiotics. The agricultural antibiotic is at least one compound or a salt thereof selected from the group consisting of polyoxin, kasugamycin, validamycin, streptomycin and oxytetracycline;
The agricultural and horticultural pest control composition according to claim 4 (excluding a pest control composition for paddy rice). The agricultural and horticultural pest control composition according to claim 5 (excluding pest control compositions for paddy rice), in which the agricultural antibiotic is polyoxin or a salt thereof. [Correction under Rule 91 25.04.2025]
The insecticidal compound (B) is
(b1) acetylcholinesterase (AChE) inhibitors,
(b2) GABA-gated chloride ion channel blockers,
(b3) a sodium channel modulator,
(b4) nicotinic acetylcholine receptor (nAChR) competitive modulators;
(b5) nicotinic acetylcholine receptor (nAChR) allosteric modulators - site I;
(b6) glutamate-gated chloride channel (GluCl) allosteric modulators;
(b7) juvenile hormone mimetics,
(b8) other non-specific (multi-site) inhibitors;
(b9) chordotonal organ TRPV channel modulators;
(b10) a mite growth inhibitor acting on CHS1;
(b11) an insect midgut membrane disrupting agent derived from a microorganism,
(b12) mitochondrial ATP synthase inhibitors,
(b13) oxidative phosphorylation uncouplers that disrupt the proton gradient;
(b14) nicotinic acetylcholine receptor (nAChR) channel blockers,
(b15) a chitin biosynthesis inhibitor acting on CHS1;
(b16) chitin biosynthesis inhibitor (type 1),
(b17) molting inhibitors (Diptera),
(b18) ecdysone receptor agonists,
(b19) octopamine receptor agonists,
(b20) mitochondrial electron transport complex III inhibitor-Qo site,
(b21) mitochondrial electron transport complex I inhibitors (METIs),
(b22) voltage-dependent sodium channel blockers,
(b23) acetyl CoA carboxylase inhibitors,
(b24) mitochondrial electron transport chain complex IV inhibitors,
(b25) mitochondrial electron transport complex II inhibitors,
(b26) ryanodine receptor modulators,
(b27) chordotonal organ nicotinamidase inhibitors,
(b28) GABA-gated chloride ion channel allosteric modulators,
(b29) baculovirus,
(b30) nicotinic acetylcholine receptor (nAChR) allosteric modulators - site II;
(b31) calcium-activated potassium channel (KCa2) modulators,
(b32) mitochondrial electron transport complex III inhibitor-Qi site,
(b33) targeted suppressors via RNA interference;
(b34) a chordotonal organ modulator (unspecified target site); and (b35) at least one compound selected from the group consisting of an agent A with an unknown or uncertain mechanism of action, a bacterial agent (excluding BT agents) with an unknown or uncertain mechanism of action, a plant-derived component including a synthetic product, extract, or unrefined oil with an unknown or uncertain mechanism of action, a fungal agent with an unknown or uncertain mechanism of action, and a physical perturbation with an unknown or uncertain mechanism of action,
The bactericidal active compound (C) is
(c1) RNA polymerase I inhibitors,
(c2) DNA/RNA biosynthesis inhibitors,
(c3) DNA topoisomerase type II (gyrase) inhibitors,
(c4) dihydroorotate dehydrogenase inhibitors in de novo pyrimidine biosynthesis,
(c5) tubulin polymerization inhibitors,
(c6) cell division (unknown site of action) inhibitor,
(c7) a spectrin-like protein delocalizer;
(c8) inhibitors of actin/myosin/fimbrin function,
(c9) complex I (NADH oxidoreductase) inhibitors,
(c10) complex II (succinate dehydrogenase) inhibitors,
(c11) complex III (ubiquinol oxidase Qo site) inhibitors,
(c12) complex III (ubiquinone reductase Qi site) inhibitors,
(c13) an uncoupler of oxidative phosphorylation,
(c14) complex III (ubiquinone reductase Qo site stigmatellin binding subsite) inhibitors,
(c15) a methionine biosynthesis inhibitor,
(c16) protein biosynthesis (ribosome translation initiation step) inhibitors,
(c17) protein biosynthesis (ribosome polypeptide elongation step) inhibitors,
(c18) MAP histidine kinase (os-2, HOG1) inhibitor in osmotic signal transduction;
(c19) MAP histidine kinase (os-1, Daf1) inhibitor in osmotic signal transduction;
(c20) methyltransferase inhibitors of phospholipid biosynthesis,
(c21) an inhibitor of cellular lipid peroxidation,
(c22) a cell membrane-permeable fatty acid inhibitor,
(c23) lipid homeostasis and transport/storage inhibitors,
(c24) a C14 demethylase inhibitor in sterol biosynthesis,
(c25) a 3-ketoreductase inhibitor in the C4 demethylation of sterol biosynthesis,
(c26) squalene epoxidase inhibitors of sterol biosynthesis,
(c27) chitin biosynthetic enzyme inhibitors,
(c28) cellulose biosynthetic enzyme inhibitors,
(c29) melanin biosynthesis reductase inhibitors,
(c30) a dehydratase inhibitor in melanin biosynthesis,
(c31) polyketamide synthase inhibitors in melanin biosynthesis,
(c32) resistance inducers for host plants (excluding saccharin or its salts),
(c33) compounds with unknown mechanism of action,
(c34) at least one compound selected from the group consisting of multi-site contact active compounds, and (c35) unclassified compounds;
2. The agricultural and horticultural pest control composition according to claim 1 (excluding a pest control composition for paddy rice). [Correction under Rule 91 25.04.2025]
The insecticidal compound (B) is
(b1) acetylcholinesterase (AChE) inhibitors,
(b2) GABAergic chloride ion (chloride ion) channel blockers,
(b3) a sodium channel modulator,
(b4) nicotinic acetylcholine receptor (nAChR) competitive modulators;
(b5) nicotinic acetylcholine receptor (nAChR) allosteric modulators - site I;
(b9) chordotonal organ TRPV channel modulators;
(b14) nicotinic acetylcholine receptor (nAChR) channel blockers,
(b16) chitin biosynthesis inhibitor (type 1),
(b18) ecdysone receptor agonists,
(b26) a ryanodine receptor modulator, and (b33) at least one compound selected from the group consisting of oxazosulfil, benzpyrimoxane, and isocyclohexameram;
The bactericidal active compound (C) is
(c1) RNA polymerase I inhibitors,
(c2) DNA/RNA biosynthesis inhibitors,
(c3) DNA topoisomerase type II (gyrase) inhibitors,
(c4) dihydroorotate dehydrogenase inhibitors in de novo pyrimidine biosynthesis,
(c5) tubulin polymerization inhibitors,
(c6) cell division (unknown site of action) inhibitor,
(c10) complex II (succinate dehydrogenase) inhibitors,
(c11) complex III (ubiquinol oxidase Qo site) inhibitors,
(c12) complex III (ubiquinone reductase Qi site) inhibitors,
(c16) protein biosynthesis (ribosome translation initiation step) inhibitors,
(c17) protein biosynthesis (ribosome polypeptide elongation step) inhibitors,
(c20) methyltransferase inhibitors of phospholipid biosynthesis,
(c24) a C14 demethylase inhibitor in sterol biosynthesis,
(c27) chitin biosynthetic enzyme inhibitors,
(c29) melanin biosynthesis reductase inhibitors,
(c31) polyketamide synthase inhibitors in melanin biosynthesis,
(c32) resistance inducers for host plants (excluding saccharin or its salts),
(c33) compounds with unknown mechanism of action,
(c34) multisite contact active compounds, and (c35) at least one compound selected from the group consisting of quinofumelin;
2. The agricultural and horticultural pest control composition according to claim 1 (excluding a pest control composition for paddy rice).