WO2025092941A1 - Sample analysis system - Google Patents

Abstract

A sample analysis system (10), comprising a sample storage apparatus (100), a sample measurement apparatus (200), a sample container transfer apparatus (300), a first photographic apparatus (400) and a control apparatus (500). The control apparatus (500) is configured to obtain a first target image on the basis of an image captured by means of the first photographic apparatus (400) executing a first photographing action, and to output at least one of the following pieces of information: the first target image, a determination result for indicating whether there are clots in an intermediate layer liquid (32), and a determination result for indicating the degree of coagulation in a blood sample (30), wherein the first target image at least includes an image showing an interface liquid surface (321) or an interface liquid layer in a two-dimensional form and/or a three-dimensional form for use as a basis for determining whether there are clots in the intermediate layer liquid (32) and/or as a basis for determining the degree of coagulation in the blood sample (30). The probability of missed detection of early coagulation in the blood sample (30) is reduced, and the accuracy of determining whether clots have formed in the blood sample (30) before aspiration is improved.

Description

Sample analysis system Technical Field

The present invention relates to the field of in vitro diagnostic equipment, and in particular to a sample analysis system.

Background Art

In the coagulation measurement of blood samples, if the blood sample produces clots and premature coagulation occurs before the measurement, it will affect the accuracy of the blood sample measurement results. The main reasons for the blood sample to produce clots before the measurement include poor blood sample collection, poor mixing of blood samples and anticoagulants, improper use of anticoagulants, etc. The impact of clots on the blood sample measurement results mainly includes two aspects: on the one hand, when the sample needle draws blood samples from the sample container, it is easy to touch the clots, resulting in inaccurate sample aspiration; on the other hand, the presence of clots in the blood sample before the measurement indicates that the blood sample has started the coagulation process before the measurement, resulting in the consumption of coagulation factors. At this time, even if the sample needle does not touch the clots and the sample is accurately drawn, it will cause abnormal sample measurement results. Although this abnormality reflects the coagulation state of the blood sample, it cannot accurately reflect the patient's coagulation parameters.

In the related art, the following two schemes are mainly used to determine whether a blood sample has clots before measurement: Scheme 1 is to find abnormal blood samples through abnormal coagulation measurement results, and manually confirm whether there are clots in the blood sample. Scheme 2 is to determine whether there are clots in the blood sample through the pressure curve when the sample needle is aspirating the sample, that is, a pressure sensor is installed in the sample aspiration liquid path of the sample needle. When the sample needle is aspirating the sample, if the sample needle touches a clot, it will cause a slight needle blockage, which can be detected from the pressure detection data of the pressure sensor.

The above two methods both have shortcomings in specific applications, which are specifically reflected as follows:

(1) In the above scheme 1, after the blood sample is measured, there is no output that can be used directly as a basis for judging whether there is a clot in the blood sample. When the coagulation test result is abnormal, it is necessary to manually go back to find the blood sample to confirm whether there is a clot in the blood sample. The operation is cumbersome, consumes a lot of manpower and time, and prolongs the time to issue the sample test report. In addition, since only when the coagulation test result is abnormal, the abnormal sample will be manually searched for confirmation, so when the blood sample has premature coagulation, the use of this scheme will still cause the problem of missed detection.

(2) In the above scheme 2, after the blood sample is measured, there is no output that can be used as a basis for accurately judging whether there is a clot in the blood sample before the sample is aspirated. Since the clot is usually only a small piece when the blood sample is prematurely coagulated, when the sample needle is inserted into the blood sample to aspirate the sample, it sometimes touches a small clot, and sometimes does not touch a clot. In addition, due to the accuracy limitation of the pressure sensor, even if the sample needle touches a small clot, it may not be able to accurately detect the presence of a clot in the blood sample. Therefore, this method has a high probability of missing the premature coagulation of the blood sample.

Summary of the invention

The first object of the present invention is to provide a sample analysis system, which aims to solve the technical problem in the related art that there is no basis for accurately judging whether a blood sample has produced a clot before aspiration.

To achieve the above object, the present invention provides a solution: a sample analysis system, comprising:

A sample storage device, the sample storage device is at least used for placing a sample container loaded with a blood sample to achieve the loading of the blood sample;

A sample measuring device, the sample measuring device is used to draw at least part of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, a middle layer liquid, and a lower layer liquid, and distribute it to a reaction container for reaction and measurement, wherein the middle layer liquid at least contains platelets and/or leukocytes;

a sample container transporting device, the sample container transporting device being used to transport the sample container placed in the sample storage device and loaded with the blood sample to the sample measuring device;

a first camera device, the first camera device being used to perform a first photographing action on the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into the upper layer liquid, the middle layer liquid, and the lower layer liquid before the sample measuring device absorbs the upper layer liquid from the sample container, wherein there is a boundary liquid surface or boundary liquid layer between the middle layer liquid and the upper layer liquid;

A control device, the control device being configured to: obtain a first target image according to the image captured by the first camera device when performing the first shooting action; output at least one of the following information according to the first target image: the first target image is used to characterize the determination result of whether the intermediate layer liquid has a clot, and is used to characterize the determination result of the degree of coagulation of the blood sample;

Among them, the first target image at least includes an image showing the interface liquid surface or the interface liquid layer in a two-dimensional form and/or a three-dimensional form, and the first target image is used as a basis for judging whether the intermediate layer liquid has a clot and/or as a basis for determining the degree of coagulation of the blood sample.

As an embodiment, the outputting at least one of the following information according to the first target image: the first target image is used to characterize the determination result of whether the intermediate layer liquid has a clot, and is used to characterize the determination result of the degree of coagulation of the blood sample, including: outputting the first target image;

Alternatively, the outputting of at least one of the following information based on the first target image: the first target image, a determination result for characterizing whether the intermediate layer liquid has a clot, and a determination result for characterizing the degree of coagulation of the blood sample, including: outputting the first target image, and outputting at least one of a determination result for characterizing whether the intermediate layer liquid has a clot and a determination result for characterizing the degree of coagulation of the blood sample.

As an embodiment, the sample analysis system further includes a reflector, and the reflector is used to: when the first camera device performs the first shooting action, reflect at least an image showing the interface liquid surface or interface liquid layer in a two-dimensional form and/or a three-dimensional form to the first camera device;

The first camera device performing the first photographing action on the sample container includes: the first camera device photographing an image of the sample container in the reflector toward the reflector.

As an embodiment, the reflector is tilted relative to the horizontal direction, and the camera optical axis of the first camera device when performing the first shooting action is perpendicular to the horizontal direction; and/or,

The reflector is used to reflect the image of the sample container from obliquely above or below the intermediate layer liquid when the first camera device performs the first shooting action; the first camera device is used to capture the image of the sample container in the reflector when performing the first shooting action.

As an embodiment, the first camera device performing the first shooting action on the sample container includes: the first camera device shooting an image of the sample container directly toward the sample container from directly above, obliquely above, or obliquely below the intermediate layer of liquid.

As an embodiment, the first camera device performs the first shooting action on the sample container, including: the first camera device is used to shoot an image of the sample container from obliquely above the intermediate layer of liquid directly toward the sample container with the camera optical axis forming a preset angle with the horizontal direction, and the preset angle is greater than or equal to 10° and less than or equal to 70°.

As an implementation manner, the preset angle is greater than or equal to 20° and less than or equal to 50°.

As an embodiment, the sample analysis system further includes a second camera device, which is used to perform a second shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and stratified before the first camera device performs the first shooting action on the sample container;

The control device is further configured to: before obtaining the first target image, control one of the sample container and the second camera device to rotate horizontally relative to the other around an axis perpendicular to the horizontal direction; during the process of the sample container and the second camera device rotating horizontally relative to the other around an axis perpendicular to the horizontal direction, control the second camera device to perform the second shooting action on the sample container, and obtain the target shooting orientation according to the image captured by the second camera device when performing the second shooting action;

The control device obtains the first target image, including: controlling one of the sample container and the first camera device to rotate horizontally relative to the other about an axis perpendicular to the horizontal direction and stop at the target shooting orientation, and controlling the first camera device to perform the first shooting action on the sample container to obtain the first target image;

The second camera device and the first camera device are the same camera device, or the second camera device and the first camera device are two independent camera devices.

As an embodiment, the control device obtains the target shooting orientation including: controlling one of the sample container and the second camera device to rotate relative to the other about an axis perpendicular to the horizontal direction by a first preset stroke, the first preset stroke being greater than or equal to 360°, and during the process in which one of the sample container and the second camera device rotates horizontally relative to the other about an axis perpendicular to the horizontal direction by the first preset stroke, controlling the second camera device to capture a first number of images of the sample container to perform the second shooting action, and determining the shooting orientation corresponding to an image in the first number of images of the sample container that displays the smallest area of an obstruction on the sample container or does not display the obstruction on the sample container as the target shooting orientation; or,

The control device obtains the target shooting orientation by: controlling one of the sample container and the second camera device to rotate relative to the other about an axis perpendicular to the horizontal direction; during the rotation of one of the sample container and the second camera device relative to the other about the axis perpendicular to the horizontal direction, controlling the second camera device to shoot images of the sample container at first preset time intervals to perform the second shooting action; when the mask on the sample container is shown in an image shot by the second camera device, When the area of the obstruction is less than or equal to a preset threshold or the obstruction on the sample container is not displayed, the shooting direction corresponding to the image showing that the area of the obstruction on the sample container is less than or equal to the preset threshold or the obstruction on the sample container is not displayed is determined as the target shooting direction.

As an embodiment, the control device obtains the first target image including: controlling one of the sample container and the first camera device to rotate relative to the other around an axis perpendicular to the horizontal direction, and during the process of one of the sample container and the first camera device rotating relative to the other around the axis perpendicular to the horizontal direction, controlling the first camera device to capture an image of the sample container to perform the first shooting action, and using an image captured by the first camera device during the process of one of the sample container and the first camera device rotating horizontally relative to the other around the axis perpendicular to the horizontal direction as the first target image.

As an embodiment, the control device obtains the first target image including: controlling one of the sample container and the first camera device to rotate relative to the other about an axis perpendicular to the horizontal direction for a second preset stroke, and during the process of rotating one of the sample container and the first camera device relative to the other about the axis perpendicular to the horizontal direction for the second preset stroke, controlling the first camera device to capture a second number of images of the sample container to perform the first capturing action, and using an image of the second number of images of the sample container that displays the smallest area of an obstruction on the sample container or does not display the obstruction on the sample container as the first target image; or,

The control device obtains the first target image including: controlling one of the sample container and the first camera device to rotate relative to the other around an axis perpendicular to the horizontal direction; during the process of one of the sample container and the first camera device rotating relative to the other around an axis perpendicular to the horizontal direction, controlling the first camera device to capture images of the sample container at second preset time intervals to perform the first shooting action; when an image captured by the first camera device shows that the area of the obstruction on the sample container is less than or equal to a preset threshold or the obstruction on the sample container is not displayed, an image in which the area of the obstruction on the sample container is less than or equal to the preset threshold or the obstruction on the sample container is not displayed is displayed as the first target image.

As an embodiment, the sample analysis system further includes a third camera device, which is used to perform a third shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and layered in a horizontal direction before the first camera device performs the first shooting action on the sample container;

The control device is further configured to: before acquiring the first target image, first control the third camera device to perform the third shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and layered, obtain the height position of the interface liquid surface or the interface liquid layer according to the image captured by the third camera device when performing the third shooting action, and obtain the target height position according to the height position of the interface liquid surface or the interface liquid layer;

The control device obtains the first target image, including: controlling one of the sample container and the first camera to move relative to the other and stop at the target height position, controlling the first camera to perform the first shooting action on the sample container, and obtaining the first target image according to an image captured by the first camera when performing the first shooting action;

The third camera device and the first camera device are the same camera device, or the third camera device and the first camera device are two independent camera devices.

As an embodiment, the control device is also configured to: control the third camera device to perform the third shooting action with a first field of view and a first object side resolution; control the first camera device to perform the first shooting action with a second field of view and a second object side resolution, wherein the first field of view is larger than the second field of view, and the first object side resolution is smaller than the second object side resolution.

As an implementation manner, the first camera device and the third camera device are the same camera device, and the first camera device includes an adjustment component, and the adjustment component is at least used to adjust the shooting angle of the first camera device;

The control device is also configured to: first control the first camera device to perform the third shooting action on the sample container in a horizontal direction, then control the adjustment component to adjust the shooting angle of the first camera device, and then control the first camera device after adjusting the shooting angle to perform the first shooting action on the sample container from obliquely above the intermediate layer of liquid.

As an embodiment, the control device is further configured to: obtain a determination result for characterizing whether the intermediate layer of liquid has a clot according to at least one of the following features: whether there is a feature for characterizing a depression in the image of the interface liquid surface or the interface liquid layer, whether there is a feature for characterizing a protrusion in the image of the interface liquid surface or the interface liquid layer; and/or,

The control device is also configured to obtain a determination result characterizing the degree of coagulation of the blood sample based on at least one of the following features: the number of features characterizing depressions in the image of the interface liquid surface or the interface liquid layer, the number of features characterizing protrusions in the image of the interface liquid surface or the interface liquid layer, and the size of features characterizing depressions in the image of the interface liquid surface or the interface liquid layer.

As an embodiment, the sample container transmission device includes a first conveying track, a first sample container scheduling mechanism and a sample container transfer device, the first conveying track is used to convey a sample holder having a single first container position, and the first container position is used to place a single sample container;

The first sample scheduling mechanism is used to schedule the sample container placed in the sample storage device and loaded with the blood sample to the sample seat located on the first conveying track;

The sample container transfer device comprises a sample seat scheduling mechanism, a second sample container scheduling mechanism and a sample rack scheduling mechanism, wherein the sample seat scheduling mechanism is at least used to transport the sample seat transported by the first transport track to the sample container transfer device to a rack position, and the second sample container scheduling mechanism is used to schedule the sample container on the sample seat at the rack position to a sample rack provided by the sample rack scheduling mechanism, wherein the sample rack has at least two second container positions, each of which is used to place a single sample container; and the sample rack scheduling mechanism is used to schedule the sample rack loaded with the sample container and the blood sample in the sample container to the sample measurement device;

The first camera device is used to perform the first shooting action on the sample container transferred from the sample container transfer device to the first shooting position, and the first shooting position is located between the first conveying track and the sample measuring device along the path of the sample container transferred by the sample container transfer device; or, the first camera device is used to perform the first shooting action on the sample container transported from the first conveying track to the first shooting position, and the first shooting position is located between the first sample scheduling mechanism and the sample container transfer device along the path of the sample container transported by the first conveying track; or, the first camera device is used to perform the first shooting action on the sample container transported from the sample measuring device to the first shooting position, and the first shooting position is located before the sample suction position of the sample measuring device along the path of the sample measuring device transporting the sample container.

As an embodiment, the sample container transmission device includes a second conveying track and a third sample container scheduling mechanism, the third sample container scheduling mechanism is used to schedule the sample container placed in the sample storage device and loaded with the blood sample to the second conveying track, and the second conveying track is used to transport the sample container to the sample measurement device;

The first camera device is used to perform the first shooting action on the sample container transported by the second conveying track to the first shooting position, and the first shooting position is located between the third sample container scheduling mechanism and the sample measuring device along the conveying path of the second conveying track; or, the first camera device is used to perform the first shooting action on the sample container dispatched by the third sample container scheduling mechanism to the first shooting position, and the first shooting position is located between the sample storage device and the second conveying track along the scheduling path of the third sample container scheduling mechanism; or, the first camera device is used to perform the first shooting action on the sample container transported by the sample measuring device to the first shooting position, and the first shooting position is located before the sample suction position of the sample measuring device along the path of the sample measuring device for transporting the sample container.

As an embodiment, the sample analysis system further comprises a centrifugal device, which is used to centrifuge the sample container loaded with the blood sample so that the blood sample is centrifugally layered into the upper layer liquid, the middle layer liquid, and the lower layer liquid;

The sample storage device is used for placing a sample container loaded with a blood sample and not subjected to a centrifugal operation to achieve the loading of the uncentrifuged blood sample, and for placing a sample container loaded with a blood sample and subjected to a centrifugal operation to achieve the loading of the centrifuged blood sample;

The sample container transmission device comprises a third conveying track and a fourth sample container scheduling mechanism, wherein the fourth sample container scheduling mechanism is used to schedule the sample container placed in the sample storage device and loaded with the blood sample to the third conveying track, and the third conveying track is used to convey the sample container loaded with the uncentrifuged blood sample to the centrifuge device for centrifugation and to convey the sample container loaded with the centrifuged blood sample to the sample measuring device;

The first camera device is used to perform the first shooting action on the sample container transported by the third transport track to the first shooting position, and the first shooting position is located between the centrifuge device and the sample measuring device along the transport path of the third transport track; or, the first camera device is used to perform the first shooting action on the sample container transported by the sample measuring device to the first shooting position, and the first shooting position is located before the sample suction position of the sample measuring device along the path for transporting the sample container by the sample measuring device.

As an embodiment, the sample container transmission device includes a sample suction and delivery channel and a fifth sample container scheduling mechanism, the sample storage device is used for placing a sample container loaded with a blood sample and subjected to a centrifugal operation to achieve the loading of the centrifuged blood sample, the fifth sample scheduling mechanism is used to schedule the sample container loaded with the blood sample placed in the sample storage device to the sample suction and delivery channel, and the sample measurement device is used to absorb at least part of the upper layer liquid from the sample container in the sample suction and delivery channel and distribute it to a reaction container for reaction and measurement;

The first camera device is used to perform the first shooting action on the sample container that is dispatched to the first shooting position by the fifth sample container scheduling mechanism, and the first shooting position is located between the sample storage device and the sample suction and delivery channel along the scheduling path of the fifth sample scheduling mechanism; or, the first camera device is used to perform the first shooting action on the sample container that is transported to the first shooting position by the sample suction and delivery channel, and the first shooting position is located before the sample suction position of the sample measuring device along the path of transporting the sample container by the sample suction and delivery channel.

As an embodiment, the control device is also configured to: based on the first target image, display at least one of the first target image, the determination result for characterizing whether there is a clot in the intermediate layer liquid, and the determination result for characterizing the degree of coagulation of the blood sample in a sample test report and/or transmit it to a laboratory information management system that is communicatively connected to the sample analysis system.

As an embodiment, the control device is further configured to: determine the degree of coagulation of the blood sample according to the first target image, and use at least two different identification methods to display at least two blood samples with different coagulation degrees on the target image. The sample test report is/are transmitted to the laboratory information management system.

As an embodiment, the sample measuring device includes a first display, and the first display is used to display at least the measuring item information of the blood sample in the sample measuring device. The control device is further configured to: display at least one of the following information on the display interface of the first display: the first target image, which is used to represent the determination result of whether the intermediate layer liquid has a clot, and the determination result of the degree of coagulation of the blood sample; and/or,

The sample analysis system also includes a second display, which is independently arranged from the sample measuring device, and the second display is at least used to display the storage information of the blood sample in the sample storage device and the information of the blood sample transmitted by the sample container transmission device. The control device is also configured to: display at least one of the following information on the display interface of the second display: the first target image, which is used to characterize the judgment result of whether the intermediate layer liquid has a clot, and which is used to characterize the judgment result of the degree of coagulation of the blood sample.

As an embodiment, the sample analysis system further includes a fourth camera device, which is used to perform a fourth shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into the upper layer liquid, the middle layer liquid, and the lower layer liquid before the sample measuring device absorbs the upper layer liquid from the sample container;

The sample measuring device includes a sample dispensing mechanism, a reagent dispensing mechanism and an optical measuring mechanism;

The sample dispensing mechanism comprises a sample needle and a needle blocking detection component, wherein the sample needle is used to absorb at least part of the upper layer of liquid from the sample container after the first camera device performs the first shooting action and the fourth camera device performs the fourth shooting action and distributes it to the reaction container, and the needle blocking detection component is used to detect a parameter used to characterize whether a needle blocking phenomenon occurs during the sample aspiration process of the sample needle;

The reagent dispensing mechanism is used to draw at least part of the reagent from the reagent container and dispense it into the reaction container;

The optical measurement mechanism is used to perform optical measurement on a reaction solution made of at least the blood sample and the reagent in the reaction container;

The control device is further configured to: obtain a second target image including the upper liquid image based on the image captured by the fourth camera device when performing the fourth capturing action; determine whether the sample needle is blocked based on feedback information from the needle blocking detection component; determine whether the blood sample has a clot and/or determine the degree of coagulation of the blood sample based on at least two of the first target image, the second target image, and a determination result of whether the sample needle is blocked;

The fourth camera device and the first camera device are the same camera device, or the fourth camera device and the first camera device are two independent camera devices.

As an embodiment, the sample measuring device comprises a sample dispensing mechanism and a measuring mechanism, wherein the sample dispensing mechanism is used to absorb at least a portion of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, an intermediate layer liquid, and a lower layer liquid, and distribute the upper layer liquid to a reaction container, wherein the intermediate layer liquid contains platelets and/or leukocytes; and the measuring mechanism is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid and a reagent;

The control device is also configured to:

When a first sample container loaded with the blood sample and having abnormal clots in the blood sample is placed in the sample storage device, the sample container transfer device is controlled to transfer the first sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the first sample container located at the first shooting position, and the sample container transfer device is controlled to transfer the first sample container after the first shooting action is completed and the upper layer of liquid loaded therein is not measured by the measuring mechanism to the first storage space;

When a second sample container loaded with the blood sample and having no abnormal clot phenomenon in the blood sample is placed in the sample storage device, the sample container transmission device is controlled to transmit the second sample container loaded with the blood sample and after the blood sample is centrifuged and stratified into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the second sample container located at the first shooting position, the sample container transmission device is controlled to transmit the second sample container after completing the first shooting action to the sample measurement device, the sample distribution mechanism is controlled to absorb at least part of the upper layer of liquid from the second sample container and distribute it to the first reaction container, and the measurement mechanism is controlled to measure the first test liquid made of at least the upper layer of liquid distributed to the first reaction container and the reagent;

Wherein, the first storage space is located in the sample storage device, or is located beside the sample container transmission device, or is located below the sample container transmission device, or is located above the sample container transmission device.

As an embodiment, the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid has not been transported by the sample container transporting device to the sample measuring device to the first storage space;

Alternatively, the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device The first sample container after the first shooting action is completed is transferred to the sample measuring device, and the sample container transfer device is controlled to transfer the first sample container output from the sample measuring device and without the upper layer of liquid being sucked out by the sample dispensing mechanism to the first storage space;

Alternatively, the sample measuring device further includes a reagent dispensing mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least part of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and before the reagent dispensing mechanism distributes the reagent to the second reaction container to the first storage space;

Alternatively, the sample measuring device further includes an incubation mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and without the incubation mechanism incubating the liquid in the second reaction container at least containing the upper layer liquid distributed from the first sample container to the second reaction container to the first storage space;

Alternatively, the sample measuring device further includes a reagent dispensing mechanism and an incubation mechanism, and the control of the sample container transmission device to transfer the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transmission device to transfer the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, controlling the incubation mechanism to incubate the liquid in the second reaction container that at least contains the upper layer liquid distributed from the first sample container to the second reaction container, controlling the reagent dispensing mechanism to distribute the reagent to the second reaction container, and controlling the sample container transmission device to transfer the first sample container that is output from the sample measuring device and the second liquid to be tested that at least contains the upper layer liquid distributed to the second reaction container and the reagent has not been measured by the measuring mechanism to the first storage space.

As an embodiment, when a first sample container loaded with the blood sample and in which an abnormal clotting phenomenon exists is placed in the sample storage device, after controlling the first camera device to perform the first shooting action on the first sample container located at the first shooting position, the control device is further configured to: output prompt information for characterizing that an abnormal clotting phenomenon exists in the blood sample in the first sample container.

A second object of the present invention is to provide a sample analysis system, the sample analysis system comprising:

A sample storage device, the sample storage device is at least used for placing a sample container loaded with a blood sample to achieve the loading of the blood sample;

A sample measuring device, the sample measuring device is used to draw at least part of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, a middle layer liquid, and a lower layer liquid, and distribute it to a reaction container for reaction and measurement, wherein the middle layer liquid at least contains platelets and/or leukocytes;

a sample container transporting device, the sample container transporting device being used to transport the sample container placed in the sample storage device and loaded with the blood sample to the sample measuring device;

a first camera device, the first camera device being used to perform a first photographing action on the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into the upper layer liquid, the middle layer liquid, and the lower layer liquid, from obliquely above or obliquely below the middle layer liquid, before the sample measuring device absorbs the upper layer liquid from the sample container;

A control device, the control device being configured to: obtain a first target image according to the image captured by the first camera device when performing the first shooting action; output at least one of the following information according to the first target image: the first target image is used to characterize the determination result of whether the intermediate layer liquid has a clot, and is used to characterize the determination result of the degree of coagulation of the blood sample;

The first target image at least includes an image of the intermediate layer of liquid, and the first target image is used as a basis for determining whether the intermediate layer of liquid has clots and/or as a basis for determining the degree of coagulation of the blood sample.

As an embodiment, the first camera device performs the first shooting action on the sample container, including: the first camera device is used to shoot an image of the sample container from obliquely above the intermediate layer of liquid directly toward the sample container with the camera optical axis forming a preset angle with the horizontal direction, and the preset angle is greater than or equal to 10° and less than or equal to 70°.

As an embodiment, the sample analysis system further includes a second camera device, which is used to perform a second shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and stratified before the first camera device performs the first shooting action on the sample container;

The control device is further configured to: before obtaining the first target image, control one of the sample container and the second camera device to rotate horizontally relative to the other around an axis perpendicular to the horizontal direction; during the process of the sample container and the second camera device rotating horizontally relative to the other around an axis perpendicular to the horizontal direction, control the second camera device to perform the second shooting action on the sample container, and obtain the target shooting orientation according to the image captured by the second camera device when performing the second shooting action;

The control device obtains the first target image in a manner including: controlling one of the sample container and the first camera device to rotate horizontally relative to the other about an axis perpendicular to the horizontal direction and stop at the target shooting orientation, and controlling the first camera device to perform the first shooting action on the sample container to obtain the first target image;

The second camera device and the first camera device are the same camera device, or the second camera device and the first camera device are two independent camera devices.

As an embodiment, the sample analysis system further includes a third camera device, which is used to perform a third shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and layered in a horizontal direction before the first camera device performs the first shooting action on the sample container;

The control device is further configured to: before acquiring the first target image, first control the third camera device to perform the third shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and layered, obtain the height position of the intermediate layer liquid according to the image captured by the third camera device when performing the third shooting action, and obtain the target height position according to the height position of the intermediate layer liquid;

The control device obtains the first target image, including: controlling one of the sample container and the first camera to move relative to the other and stop at the target height position, controlling the first camera to perform the first shooting action on the sample container, and obtaining the first target image according to an image captured by the first camera when performing the first shooting action;

The third camera device and the first camera device are the same camera device, or the third camera device and the first camera device are two independent camera devices.

As an embodiment, the sample analysis system further includes a fourth camera device, which is used to perform a fourth shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into the upper layer liquid, the middle layer liquid, and the lower layer liquid before the sample measuring device absorbs the upper layer liquid from the sample container;

The sample measuring device includes a sample dispensing mechanism, a reagent dispensing mechanism and an optical measuring mechanism;

The sample dispensing mechanism comprises a sample needle and a needle blocking detection component, wherein the sample needle is used to absorb at least part of the upper layer of liquid from the sample container after the first camera device performs the first shooting action and the fourth camera device performs the fourth shooting action and distributes it to the reaction container, and the needle blocking detection component is used to detect a parameter used to characterize whether a needle blocking phenomenon occurs during the sample aspiration process of the sample needle;

The reagent dispensing mechanism is used to draw at least part of the reagent from the reagent container and dispense it into the reaction container;

The optical measurement mechanism is used to perform optical measurement on a reaction solution made of at least the blood sample and the reagent in the reaction container;

The control device is further configured to: obtain a second target image including the upper liquid image based on the image captured by the fourth camera device when performing the fourth capturing action; determine whether the sample needle is blocked based on feedback information from the needle blocking detection component; determine whether the blood sample has a clot and/or determine the degree of coagulation of the blood sample based on at least two of the first target image, the second target image, and a determination result of whether the sample needle is blocked;

The fourth camera device and the first camera device are the same camera device, or the fourth camera device and the first camera device are two independent camera devices.

As an embodiment, the sample measuring device comprises a sample dispensing mechanism and a measuring mechanism, wherein the sample dispensing mechanism is used to absorb at least a portion of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, an intermediate layer liquid, and a lower layer liquid, and distribute the upper layer liquid to a reaction container, wherein the intermediate layer liquid contains platelets and/or leukocytes; and the measuring mechanism is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid and a reagent;

The control device is also configured to:

When a first sample container loaded with the blood sample and having abnormal clots in the blood sample is placed in the sample storage device, the sample container transfer device is controlled to transfer the first sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the first sample container located at the first shooting position, and the sample container transfer device is controlled to transfer the first sample container after the first shooting action is completed and the upper layer of liquid loaded therein is not measured by the measuring mechanism to the first storage space;

When a second sample container loaded with the blood sample and having no abnormal clot phenomenon in the blood sample is placed in the sample storage device, the sample container transfer device is controlled to transfer the second sample container loaded with the blood sample and having the blood sample centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, and the first camera device is controlled to focus on the second sample container at the first shooting position. The second sample container at a shooting position performs the first shooting action, controls the sample container transport device to transport the second sample container after the first shooting action to the sample measuring device, controls the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the second sample container and distribute it to the first reaction container, and controls the measuring mechanism to measure the first liquid to be tested which is made of at least the upper layer liquid distributed to the first reaction container and a reagent;

Wherein, the first storage space is located in the sample storage device, or is located beside the sample container transmission device, or is located below the sample container transmission device, or is located above the sample container transmission device.

As an embodiment, the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid has not been transported by the sample container transporting device to the sample measuring device to the first storage space;

Alternatively, the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and the upper layer liquid has not been sucked out of it by the sample dispensing mechanism to the first storage space;

Alternatively, the sample measuring device further includes a reagent dispensing mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least part of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and before the reagent dispensing mechanism distributes the reagent to the second reaction container to the first storage space;

Alternatively, the sample measuring device further includes an incubation mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and without the incubation mechanism incubating the liquid in the second reaction container at least containing the upper layer liquid distributed from the first sample container to the second reaction container to the first storage space;

Alternatively, the sample measuring device further includes a reagent dispensing mechanism and an incubation mechanism, and the control of the sample container transmission device to transfer the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transmission device to transfer the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, controlling the incubation mechanism to incubate the liquid in the second reaction container that at least contains the upper layer liquid distributed from the first sample container to the second reaction container, controlling the reagent dispensing mechanism to distribute the reagent to the second reaction container, and controlling the sample container transmission device to transfer the first sample container that is output from the sample measuring device and the second liquid to be tested that at least contains the upper layer liquid distributed to the second reaction container and the reagent has not been measured by the measuring mechanism to the first storage space.

As an embodiment, when a first sample container loaded with the blood sample and in which an abnormal clotting phenomenon exists is placed in the sample storage device, after controlling the first camera device to perform the first shooting action on the first sample container located at the first shooting position, the control device is further configured to: output prompt information for characterizing that an abnormal clotting phenomenon exists in the blood sample in the first sample container.

A third object of the present invention is to provide a sample analysis system, the sample analysis system comprising:

A sample storage device, the sample storage device is at least used for placing a sample container loaded with a blood sample to achieve the loading of the blood sample;

A sample measuring device, the sample measuring device is used to draw at least part of the upper layer liquid from the sample container containing the blood sample after centrifugation into an upper layer liquid, a middle layer liquid, and a lower layer liquid, and distribute it to a reaction container for reaction and measurement, wherein the middle layer liquid at least contains platelets and/or leukocytes;

a sample container transporting device, the sample container transporting device being used to transport the sample container placed in the sample storage device and loaded with the blood sample to the sample measuring device;

The first camera device is used for capturing the upper layer of liquid, the middle layer of liquid, the lower layer of liquid, the sample container loaded with the blood sample and the blood sample is centrifuged and separated into the upper layer of liquid, the middle layer of liquid, and the lower layer of liquid before the sample measuring device draws the upper layer of liquid from the sample container. The sample container behind the liquid performs a first shooting action;

a reflector, the reflector being used to: when the first camera device performs the first shooting action, reflect the image at least including the intermediate layer of liquid to the first camera device; the first camera device performing the first shooting action on the sample container comprises: the first camera device shoots the image of the sample container in the reflector toward the reflector;

A control device, the control device being configured to: obtain a first target image according to the image captured by the first camera device when performing the first shooting action; output at least one of the following information according to the first target image: the first target image is used to characterize the determination result of whether the intermediate layer liquid has a clot, and is used to characterize the determination result of the degree of coagulation of the blood sample;

The first target image at least includes an image of the intermediate layer of liquid, and the first target image is used as a basis for determining whether the intermediate layer of liquid has clots and/or as a basis for determining the degree of coagulation of the blood sample.

As an embodiment, the reflector is tilted relative to the horizontal direction, and the optical axis of the first camera device when performing the first shooting action is perpendicular to the horizontal direction; and/or,

The reflector is used to reflect the image of the sample container from obliquely above or below the intermediate layer liquid when the first camera device performs the first shooting action; the first camera device is used to capture the image of the sample container in the reflector when performing the first shooting action.

As an embodiment, the sample analysis system further includes a second camera device, which is used to perform a second shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and stratified before the first camera device performs the first shooting action on the sample container;

The control device is further configured to: before obtaining the first target image, control one of the sample container and the second camera device to rotate horizontally relative to the other around an axis perpendicular to the horizontal direction; during the process of the sample container and the second camera device rotating horizontally relative to the other around an axis perpendicular to the horizontal direction, control the second camera device to perform the second shooting action on the sample container, and obtain the target shooting orientation according to the image captured by the second camera device when performing the second shooting action;

The control device obtains the first target image, including: controlling one of the sample container and the first camera device to rotate horizontally relative to the other about an axis perpendicular to the horizontal direction and stop at the target shooting orientation, and controlling the first camera device to perform the first shooting action on the sample container to obtain the first target image;

The second camera device and the first camera device are the same camera device, or the second camera device and the first camera device are two independent camera devices.

As an embodiment, the sample analysis system further includes a third camera device, which is used to perform a third shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and layered in a horizontal direction before the first camera device performs the first shooting action on the sample container;

The control device is further configured to: before acquiring the first target image, first control the third camera device to perform the third shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and layered, obtain the height position of the intermediate layer liquid according to the image captured by the third camera device when performing the third shooting action, and obtain the target height position according to the height position of the intermediate layer liquid;

The control device obtains the first target image, including: controlling one of the sample container and the first camera to move relative to the other and stop at the target height position, controlling the first camera to perform the first shooting action on the sample container, and obtaining the first target image according to an image captured by the first camera when performing the first shooting action;

The third camera device and the first camera device are the same camera device, or the third camera device and the first camera device are two independent camera devices.

As an embodiment, the sample analysis system further includes a fourth camera device, which is used to perform a fourth shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into the upper layer liquid, the middle layer liquid, and the lower layer liquid before the sample measuring device absorbs the upper layer liquid from the sample container;

The sample measuring device includes a sample dispensing mechanism, a reagent dispensing mechanism and an optical measuring mechanism;

The sample dispensing mechanism comprises a sample needle and a needle blocking detection component, wherein the sample needle is used to absorb at least part of the upper layer of liquid from the sample container after the first camera device performs the first shooting action and the fourth camera device performs the fourth shooting action and distributes it to the reaction container, and the needle blocking detection component is used to detect a parameter used to characterize whether a needle blocking phenomenon occurs during the sample aspiration process of the sample needle;

The reagent dispensing mechanism is used to draw at least part of the reagent from the reagent container and dispense it into the reaction container;

The optical measurement mechanism is used to perform optical measurement on a reaction solution made of at least the blood sample and the reagent in the reaction container;

The control device is further configured to: obtain a second target image including the upper liquid image according to the image captured by the fourth camera device performing the fourth shooting action; and determine whether the sample needle is blocked according to the feedback information of the needle blocking detection component. According to at least two of the first target image, the second target image and the result of determining whether the sample needle is blocked, determining whether the blood sample has a clot and/or determining the degree of coagulation of the blood sample;

The fourth camera device and the first camera device are the same camera device, or the fourth camera device and the first camera device are two independent camera devices.

As an embodiment, the sample measuring device comprises a sample dispensing mechanism and a measuring mechanism, wherein the sample dispensing mechanism is used to absorb at least a portion of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, an intermediate layer liquid, and a lower layer liquid, and distribute the upper layer liquid to a reaction container, wherein the intermediate layer liquid contains platelets and/or leukocytes; and the measuring mechanism is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid and a reagent;

The control device is also configured to:

When a first sample container loaded with the blood sample and having abnormal clots in the blood sample is placed in the sample storage device, the sample container transfer device is controlled to transfer the first sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the first sample container located at the first shooting position, and the sample container transfer device is controlled to transfer the first sample container after the first shooting action is completed and the upper layer of liquid loaded therein is not measured by the measuring mechanism to the first storage space;

When a second sample container loaded with the blood sample and having no abnormal clot phenomenon in the blood sample is placed in the sample storage device, the sample container transmission device is controlled to transmit the second sample container loaded with the blood sample and after the blood sample is centrifuged and stratified into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the second sample container located at the first shooting position, the sample container transmission device is controlled to transmit the second sample container after completing the first shooting action to the sample measurement device, the sample distribution mechanism is controlled to absorb at least part of the upper layer of liquid from the second sample container and distribute it to the first reaction container, and the measurement mechanism is controlled to measure the first test liquid made of at least the upper layer of liquid distributed to the first reaction container and the reagent;

Wherein, the first storage space is located in the sample storage device, or is located beside the sample container transmission device, or is located below the sample container transmission device, or is located above the sample container transmission device.

As an embodiment, the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid has not been transported by the sample container transporting device to the sample measuring device to the first storage space;

Alternatively, the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and the upper layer liquid has not been sucked out of it by the sample dispensing mechanism to the first storage space;

Alternatively, the sample measuring device further includes a reagent dispensing mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least part of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and before the reagent dispensing mechanism distributes the reagent to the second reaction container to the first storage space;

Alternatively, the sample measuring device further includes an incubation mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and without the incubation mechanism incubating the liquid in the second reaction container at least containing the upper layer liquid distributed from the first sample container to the second reaction container to the first storage space;

Alternatively, the sample measuring device further includes a reagent dispensing mechanism and an incubation mechanism, and the controlling the sample container transmission device to transmit the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transmission device to transmit the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, controlling the incubation mechanism to incubate the liquid in the second reaction container at least containing the upper layer liquid distributed from the first sample container to the second reaction container, controlling the reagent dispensing mechanism to distribute the reagent to the second reaction container, and controlling the sample container transmission device to output from the sample measuring device and the upper layer liquid loaded therein has not been measured by the measuring mechanism The first sample container containing at least the upper layer liquid distributed into the second reaction container and the second test liquid of the reagent for measurement is transferred to the first storage space.

As an embodiment, when a first sample container loaded with the blood sample and in which an abnormal clotting phenomenon exists is placed in the sample storage device, after controlling the first camera device to perform the first shooting action on the first sample container located at the first shooting position, the control device is further configured to: output prompt information for characterizing that an abnormal clotting phenomenon exists in the blood sample in the first sample container.

The sample analysis system provided by the present invention performs a first shooting action on the sample container loaded with the blood sample and after the blood sample is centrifugally stratified into an upper layer liquid, an intermediate layer liquid, and a lower layer liquid by a first camera device before the sample measuring device draws the blood sample from the sample container, thereby obtaining a first target image, and making the first target image at least include an image showing the interface liquid surface or interface liquid layer formed between the intermediate layer liquid and the upper layer liquid in a two-dimensional form and/or a three-dimensional form, and using the image showing the interface liquid surface or interface liquid layer formed between the intermediate layer liquid and the upper layer liquid in a two-dimensional form and/or a three-dimensional form as a basis for judging whether the intermediate layer liquid has a clot and/or as a basis for determining the degree of coagulation of the blood sample. In this way, the phenomenon that if the blood sample produces a clot, the clot will cause the intermediate layer liquid to be uneven can be used to accurately judge whether the blood sample produces a clot before the sample is drawn and/or the degree of coagulation of the blood sample, thereby improving the accuracy of judging whether the blood sample produces a clot before the sample is drawn, thereby facilitating eliminating the influence of premature coagulation on the accuracy of the blood sample measurement result. The present invention uses a non-contact imaging method to determine whether a blood sample has produced a clot before sample aspiration and/or the degree of coagulation of the blood sample. Compared with the solution in the related art that uses a method of changing the pressure of a needle blocking the sample to determine whether a blood sample has produced a clot before sample aspiration, the present invention has the following beneficial effects: the imaging method of the present invention is not affected by the size of the clot and the sensitivity of the sensor, which helps to reduce the probability of missed detection of premature coagulation of the blood sample and improves the accuracy of determining whether a blood sample has produced a clot before sample aspiration.

BRIEF DESCRIPTION OF THE DRAWINGS

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on the structures shown in these drawings without paying creative work.

FIG1 is a schematic diagram of the structure of a sample analysis system provided in Embodiment 1 of the present invention;

2 is a schematic diagram showing the principle of the first camera device according to the first embodiment of the present invention indirectly capturing an image of a sample container through a first reflecting mirror to perform a first capturing action;

3 is a schematic diagram showing the principle of the third camera device provided in the first embodiment of the present invention indirectly capturing the image of the sample container through the second reflecting mirror to perform a third capturing action;

4 is a schematic diagram showing the principle of the third camera device directly capturing an image of a sample container to perform a third capturing action provided by the first embodiment of the present invention;

FIG5 is a schematic diagram of the structure of a sample measurement device provided in Embodiment 1 of the present invention;

FIG6 is a schematic diagram of the composition of a sample analysis system provided in Embodiment 1 of the present invention;

7 is a schematic diagram showing the principle of the first camera device directly capturing an image of a sample container to perform a first capturing action provided by the second embodiment of the present invention;

FIG8 is a schematic diagram of the structure of a sample analysis system provided in Embodiment 6 of the present invention;

FIG9 is a schematic diagram of the structure of a sample analysis system provided in Embodiment 7 of the present invention;

FIG. 10 is a schematic diagram of the structure of a sample analysis system provided in Embodiment 8 of the present invention.

Explanation of the accompanying drawings: 10, sample analysis system; 100, sample storage device; 200, sample measurement device; 210, sample suction and delivery channel; 220, sample distribution mechanism; 230, measurement mechanism; 240, incubation mechanism; 250, reagent distribution mechanism; 251, mixed reagent dispensing assembly; 252, trigger reagent dispensing assembly; 260, reagent tray; 270, reaction container supply mechanism; 280, reaction container transport mechanism; 300, sample container transmission device; 310, first conveying track; 320, first sample container scheduling mechanism; 330, sample container transfer device; 340, second conveying track ; 350, third sample container scheduling mechanism; 360, third conveying track; 370, fourth sample container scheduling mechanism; 380, fifth sample container scheduling mechanism; 400, first camera device; 500, control device; 600, first reflector; 700, third camera device; 800, first fill light component; 900, centrifugal device; 101, first display; 102, third fill light component; 103, second reflector; 20, sample container; 30, blood sample; 31, upper layer liquid; 32, middle layer liquid; 321, interface liquid surface; 33, lower layer liquid; A, preset angle; MN, axis.

DETAILED DESCRIPTION

The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

The technical solutions between the various embodiments can be combined with each other, but they must be based on the fact that ordinary technicians in the field can implement them. When the combination of technical solutions is contradictory or cannot be implemented, it should be deemed that such combination of technical solutions does not exist and is not within the scope of protection required by the present invention.

The sample analysis system provided in the embodiment of the present application is applicable to an analysis system in which a camera device is used to photograph a sample container and the object to be tested includes at least a blood sample collected from a human or an animal. The blood sample determination by the sample analysis system includes but is not limited to coagulation detection items.

Prior to this application, the erroneous coagulation test results of some blood samples were caused by the quality of the blood samples before the coagulation test. Before the sample analysis system performs a coagulation test on the blood sample, the blood sample may have at least one of the following quality problems: the HIL of the blood sample (HIL includes the hemolysis index H, the icterus index I, and the lipemia index L) exceeds the anti-interference ability of the test item; the total liquid volume of the blood sample is less than the liquid volume threshold; the HCT (hematocrit) of the blood sample is greater than the first hematocrit threshold; the HCT of the blood sample is less than the second hematocrit threshold; there is an abnormal clot in the blood sample. If there are serious quality problems with the blood sample before the coagulation test, the coagulation test results obtained may only reflect the problems of the blood sample, but cannot reflect the true coagulation function of the patient to whom the blood sample belongs.

Embodiment 1:

As shown in FIGS. 1 to 6 , the sample analysis system 10 provided in the first embodiment of the present invention includes a sample storage device 100, a sample measuring device 200 and a sample container transmission device 300. The sample storage device 100 is at least used for placing a sample container 20 loaded with a blood sample 30 to achieve the loading of the blood sample 30; the sample measuring device 200 is used to absorb at least part of the upper layer liquid 31 from the sample container 20 loaded with the blood sample 30 and distribute it to the reaction container for reaction and measurement; the sample container transmission device 300 is used to transfer the sample container 20 loaded with the blood sample 30 placed in the sample storage device 100 to the sample measuring device 200. The sample storage device 100 can be used to realize the sample loading function, and the sample container 20 loaded with the blood sample 30 can be placed in the sample storage device 100 by an operator or an operating robot. The sample container transmission device 300 is used to realize the sample transmission function. The sample measuring device 200 is used to perform the measurement items of the blood sample 30.

As an embodiment, the sample measuring device 200 is used to measure the centrifuged blood sample 30, that is, the sample measuring device 200 is used to draw at least a portion of the centrifuged blood sample 30 from the sample container 20 loaded with the blood sample 30 and the blood sample 30 after centrifugation and distribute it to the reaction container for reaction and measurement.

As an embodiment, the sample measuring device 200 is used to measure the upper layer liquid 31 in the centrifuged blood sample 30, that is, the sample measuring device 200 is used to absorb at least part of the upper layer liquid 31 from the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and separated into the upper layer liquid 31, the middle layer liquid 32, and the lower layer liquid 33, and distribute it to the reaction container for reaction and measurement. The middle layer liquid 32 contains at least platelets and/or white blood cells. The middle layer liquid 32 is also called the buffy coat layer, the upper layer liquid 31 is plasma or serum, and the lower layer liquid 33 is red blood cells. The blood sample 30 collected from the patient and stored in the sample container 20 is a whole blood sample. In this embodiment, the sample measuring device 200 is used to perform measurement items on the upper layer liquid 31 obtained after the blood sample 30 is centrifuged. Of course, in specific applications, as an alternative implementation, other measuring devices may be provided in the sample analysis system 10 for performing measurement items on the middle layer liquid and/or the lower layer liquid 33; or, as another alternative implementation, other measuring devices may be provided in the sample analysis system 10 for performing measurement items on the uncentrifuged blood sample 30 (i.e., the whole blood sample).

As an embodiment, the sample analysis system 10 further includes a first camera device 400 and a control device 500. The first camera device 400 is used to perform a first shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and separated into the upper layer liquid 31, the middle layer liquid 32, and the lower layer liquid 33 before the sample measuring device 200 absorbs the upper layer liquid 31 from the sample container 20. The control device 500 is configured to obtain a first target image based on an image captured by the first camera device 400 when performing the first shooting action. The first camera device 400 is mainly used to capture the sample container 20 after centrifugation and before the sample is aspirated, and feed the captured image back to the control device 500.

As an embodiment, the first target image is used as a basis for judging whether the intermediate layer liquid 32 has a clot and/or as a basis for determining the degree of coagulation of the blood sample 30. The degree of coagulation of the blood sample 30 includes whether the blood sample 30 has not coagulated prematurely and the degree of premature coagulation, for example, it can specifically include the following three degrees: no premature coagulation, slight premature coagulation, and severe premature coagulation. The degree of coagulation of the blood sample 30 can be determined by whether there is a clot, and the size and number of the clots. The premature coagulation phenomenon of the blood sample 30 specifically refers to: the phenomenon that the blood sample 30 produces a clot before the sample is sucked. This embodiment uses a non-contact image method to judge whether the blood sample 30 has produced a clot before the sample is sucked and/or the degree of coagulation of the blood sample 30, which has the following beneficial effects: it is not affected by the size of the clot and the sensitivity of the sensor, which is conducive to reducing the probability of missed detection of premature coagulation of the blood sample 30, and improving the accuracy of judging whether the blood sample 30 has produced a clot before the sample is sucked.

As an embodiment, the first target image at least includes an image of the middle liquid layer. It has been found through research that after centrifugation, the middle liquid layer of a normal blood sample 30 (a blood sample 30 without premature coagulation) is very flat; while the blood sample 30 with premature coagulation is characterized by an uneven middle liquid layer (sometimes characterized by an uneven middle liquid layer, and sometimes characterized by a layer of loose floating objects coagulated by fibrin covering the middle liquid layer, which is mainly caused by the size, cause, and time of the clot). The main reason for the uneven middle liquid layer of a blood sample 30 with premature coagulation is that, for example, when the blood sample 30 and the anticoagulant are not mixed well, the blood sample 30 has coagulated before centrifugation. The main mechanism of coagulation is that the fibrinogen in the plasma forms fibrin under the action of a series of coagulation factors, and the fibrin will wrap the blood cells to form a clot. After centrifugation, if the density of the clot is between that of red blood cells and plasma, the clot is near the middle liquid layer, which will cause the middle liquid layer to be uneven. In addition, some of the formed clots contain more platelets, while others contain more platelets. There are many red blood cells wrapped, so the density of clots at different positions is different, which is also one of the reasons why the clots make the middle liquid layer uneven. In this embodiment, an image containing the middle liquid layer is used as a basis for judging whether there are clots in the middle layer liquid 32 and/or as a basis for determining the degree of coagulation of the blood sample 30, which is conducive to improving the accuracy of judging the premature coagulation phenomenon.

As an embodiment, there is a boundary liquid surface 321 or a boundary liquid layer between the intermediate layer liquid 32 and the upper layer liquid 31. The boundary liquid surface 321 can be specifically the upper surface of the intermediate layer liquid 32, that is, the horizontal liquid surface of the intermediate layer liquid 32. The first target image at least includes an image showing the boundary liquid surface 321 or the boundary liquid layer in a two-dimensional form and/or a three-dimensional form, and the first target image is used as a basis for judging whether there is a clot in the intermediate layer liquid 32 and/or as a basis for determining the degree of coagulation of the blood sample 30. The first target image can show an image of the buffy coat layer. For the convenience of description and understanding, the first target image can also be referred to as a buffy coat layer image. A one-dimensional form refers to a form that extends in only one direction, and a one-dimensional form has only length elements, such as a line, a point, etc. A two-dimensional form refers to a form that extends in only two directions, and a two-dimensional form has only two elements, length and width, such as a plane, etc. A three-dimensional form refers to a form that has three directions, and a three-dimensional form has three elements, length, width, and height. In the related art prior to the present application, there is also a solution of using a camera device to photograph the sample container 20 from the side of the sample container 20. In the solution of the related art, although the captured image also includes an image of the interface liquid surface 321, the interface liquid surface 321 is displayed in the form of a line, which is used to determine the height position of the interface liquid surface 321; due to the solution of the related art, it is impossible to see the two-dimensional and/or three-dimensional form of the interface liquid surface 321 or the interface liquid layer, so it cannot be used as a basis for clot detection of the intermediate layer liquid 32, and cannot be used as a basis for determining whether the intermediate layer liquid 32 has a clot and/or as a basis for determining the degree of coagulation of the blood sample 30. In the present application, by displaying the interface liquid surface 321 or the interface liquid layer in a two-dimensional form and/or a three-dimensional form through an image, it is helpful to see whether the interface liquid surface 321 or the interface liquid layer has an unevenness problem, so that the image containing the interface liquid surface 321 or the interface liquid layer displayed in a two-dimensional form and/or a three-dimensional form can be used as a basis for clot detection of the intermediate layer liquid 32, and can be used as a basis for judging whether the intermediate layer liquid 32 has a clot and/or as a basis for determining the degree of coagulation of the blood sample 30.

As an embodiment, the first target image at least includes an image showing the interface liquid surface 321 in a two-dimensional form, that is, the first target image at least includes an image showing the top horizontal liquid surface of the intermediate layer liquid 32 in a two-dimensional form. In this embodiment, the image of the interface liquid surface 321 is displayed in a plane, so that it is helpful to clearly see whether the interface liquid surface 321 has an uneven problem through the first target image.

As an embodiment, the first target image at least includes an image showing the entire interface liquid surface 321 in a two-dimensional form, that is, the first target image at least includes an image showing the entire top horizontal liquid surface of the intermediate layer liquid 32 in a two-dimensional form. In this embodiment, the image of the entire interface liquid surface 321 is displayed in a plane, so that it is convenient to fully and clearly see whether the interface liquid surface 321 has unevenness through the first target image, which is convenient to avoid the problem of missed detection.

As an embodiment, the control device 500 is further configured to: output at least one of the following information according to the first target image: the first target image, a determination result for characterizing whether the intermediate layer liquid 32 has a clot, and a determination result for characterizing the degree of coagulation of the blood sample 30. If the control device 500 outputs the first target image, the subsequent operator or medical staff can judge (by manually viewing the image or transmitting the first target image to other instruments for detection and judgment) whether the blood sample 30 has premature coagulation and/or the degree of premature coagulation according to the image of the interface liquid surface 321 or the interface liquid layer displayed in the first target image, without having to find the blood sample 30 for confirmation. If the control device 500 outputs a determination result for characterizing whether the intermediate layer liquid 32 has a clot and/or a determination result for characterizing the degree of coagulation of the blood sample 30, the operator or medical staff does not need to judge whether the blood sample 30 has premature coagulation and/or the degree of premature coagulation by themselves.

As an embodiment, the sample analysis system 10 further includes a reflector, which is used to: when the first camera device 400 performs the first shooting action, reflect at least an image showing the interface liquid surface 321 or the interface liquid layer in a two-dimensional form and/or a three-dimensional form to the first camera device 400. The first camera device 400 performs the first shooting action on the sample container 20, including: the first camera device 400 shoots the image of the sample container 20 in the reflector toward the reflector. Since the first camera device 400 has a requirement for the focus position when performing the first shooting action, in this embodiment, the reflector is used to reflect the image showing the interface liquid surface 321 or the interface liquid layer in a two-dimensional form and/or a three-dimensional form to the first camera device 400, which is conducive to changing the propagation path of the light, so that the shooting focus position of the first camera device 400 is changed to the distance between the first camera device 400 and the reflector, thereby facilitating the reduction of the distance between the first camera device 400 and the sample container 20, and further facilitating the reduction of the volume of the sample analysis system 10.

As an embodiment, the reflector is tilted relative to the horizontal direction. When the first camera device 400 performs the first shooting action, the camera optical axis is perpendicular to the horizontal direction, that is, the camera optical axis of the first camera device 400 when performing the first shooting action is set in the vertical direction. The first camera device 400 can be arranged above or below the reflector in the vertical direction. Since the sample container 20 is arranged in the vertical direction when performing the first shooting action, that is, the height direction of the sample container 20 is parallel to the vertical direction, the camera optical axis of the first camera device 400 is parallel to the height direction of the sample container 20, which is conducive to reducing the horizontal distance between the first camera device 400 and the sample container 20, thereby helping to reduce the horizontal footprint of the sample analysis system 10. Of course, in specific applications, the arrangement of the reflector and the first camera device 400 is not limited to this. For example, the position and orientation of the reflector and the first camera device 400 can also be adjusted, that is, the camera optical axis of the first camera device 400 is not necessarily along the vertical direction, and can also have a certain inclination angle, as long as the first camera device 400 can capture an image containing the interface liquid surface 321 or the interface liquid layer displayed in two-dimensional form and/or three-dimensional form through the reflector.

As an embodiment, the reflector is used to reflect the oblique upper surface of the intermediate layer of liquid 32 when the first camera device 400 performs the first shooting action. The first camera device 400 is used to capture the image of the sample container 20 in the reflector when performing the first shooting action. In this embodiment, the reflector reflects upward from the side of the sample container 20 an image including the interface liquid surface 321 or the interface liquid layer in a two-dimensional form and/or a three-dimensional form, and the first camera device 400 captures the image including the interface liquid surface 321 or the interface liquid layer in a two-dimensional form and/or a three-dimensional form in the reflector from above the reflector. Of course, in specific applications, the relative positions of the reflector and the first camera device 400 are not limited thereto. For example, as an alternative embodiment, the reflector is used to reflect the image of the sample container 20 from obliquely below the intermediate layer of liquid 32 when the first camera device 400 performs a first shooting action; the first camera device 400 is used to capture the image of the sample container 20 in the reflector when performing the first shooting action. In this alternative embodiment, the reflector reflects downward from the side of the sample container 20, including an image of the interface liquid surface 321 or the interface liquid layer displayed in a two-dimensional form and/or a three-dimensional form, and the first camera device 400 captures the image of the interface liquid surface 321 or the interface liquid layer displayed in a two-dimensional form and/or a three-dimensional form in the reflector from below the reflector.

As an embodiment, the sample analysis system 10 further includes a second camera device, which is used to perform a second shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered before the first camera device 400 performs the first shooting action on the sample container 20; the control device 500 is also configured to: obtain a target shooting orientation according to the image captured by the second camera device performing the second shooting action; based on the target shooting orientation, control the first camera device 400 to perform the first shooting action on the sample container 20 to obtain a first target image. The target shooting orientation here can be a specific orientation or a range value of an orientation. The outer side of the sample container 20 is provided with obstructions such as label paper. In order to ensure that the first camera device 400 can capture an image containing an interface liquid surface 321 or an interface liquid layer displayed in a two-dimensional form and/or a three-dimensional form, it is necessary to find an orientation with few or no obstructions for shooting, and the orientation with few or no obstructions is the target shooting orientation. In this embodiment, the second shooting action is first used to find the target shooting position with few or no obstructions, which helps to ensure that the first shooting action is based on the target shooting position and can accurately capture an image containing the interface liquid surface 321 or the interface liquid layer displayed in two-dimensional and/or three-dimensional form.

As an embodiment, the control device 500 is further configured to: before obtaining the first target image, control one of the sample container 20 and the second camera device to rotate horizontally relative to the other around an axis MN perpendicular to the horizontal direction, and during the process of the sample container 20 and the second camera device rotating horizontally relative to the other around an axis MN perpendicular to the horizontal direction, control the second camera device to perform a second shooting action on the sample container 20, and obtain the target shooting orientation according to the image captured by the second camera device performing the second shooting action. The control device 500 obtains the first target image including: controlling one of the sample container 20 and the first camera device 400 to rotate horizontally relative to the other around an axis MN perpendicular to the horizontal direction and stop at the target shooting orientation, and controlling the first camera device 400 to perform the first shooting action on the sample container 20 to obtain the first target image. The sample container 20 and the second camera device rotate horizontally around the axis MN perpendicular to the horizontal direction, that is, the sample container 20 and the second camera device rotate horizontally around the vertically arranged axis MN. In this embodiment, the sample container 20 and the second camera device are arranged to be relatively rotatable horizontally, so that during the rotation process, it is helpful to find a position with few or no obstructions as the target shooting position.

As an embodiment, the control device 500 obtains the target shooting orientation including: controlling one of the sample container 20 and the second camera device to rotate relative to the other about an axis MN perpendicular to the horizontal direction by a first preset stroke, the first preset stroke being greater than or equal to 360°, and in the process of the sample container 20 and the second camera device being horizontally rotated relative to the other about an axis MN perpendicular to the horizontal direction by the first preset stroke, controlling the second camera device to capture a first number of images of the sample container 20 to perform a second shooting action, and determining the shooting orientation corresponding to an image in the first number of images of the sample container 20 that shows the smallest area of occlusions on the sample container 20 or does not show occlusions on the sample container 20 as the target shooting orientation. In this embodiment, in the process of the sample container 20 and the second camera device being horizontally rotated relative to each other by the first preset stroke, multiple images are captured, and an image in which the area of occlusions is the smallest or there is no occlusion is found among the multiple images, and the shooting orientation corresponding to the image is determined as the target shooting orientation. Since the first preset stroke is greater than or equal to 360°, that is, one of the sample container 20 and the second camera device rotates horizontally around the vertical axis MN at least once, it is beneficial to capture images of each orientation of the sample container 20 during the relative horizontal rotation of the sample container 20 and the second camera device by the first preset stroke.

As an implementation mode, the first preset stroke is equal to 360°, and the target shooting direction can be determined by rotating one of the sample container 20 and the second camera device relative to the other. In this implementation mode, the first preset stroke is set to 360°, which is conducive to reducing unnecessary rotation movements, thereby facilitating improving the sample analysis efficiency of the sample analysis system 10.

As an implementation mode, the second camera device and the first camera device 400 are the same camera device, that is, the first camera device 400 is reused to perform the second shooting action and the first shooting action, which is conducive to reducing the number of camera devices and reducing the cost of the sample analysis system 10. Of course, in a specific application, as an alternative implementation mode, the second camera device and the first camera device 400 can also be set as two independent camera devices, that is, the second camera device and the first camera device 400 can be two different camera devices.

As an embodiment, the sample analysis system 10 also includes a first rotation drive mechanism, which is used to drive the sample container 20 to rotate horizontally around an axis MN perpendicular to the horizontal direction. The control device 500 is also configured to: when executing the second shooting action, control the first rotation drive mechanism to drive the sample container 20 to rotate horizontally around the axis MN perpendicular to the horizontal direction for a first preset stroke; when executing the first shooting action, control the first rotation drive mechanism to drive the sample container 20 to rotate horizontally around the axis MN perpendicular to the horizontal direction and stop at the target shooting position. In this embodiment, the target shooting position is found by driving the sample container 20 to rotate, while the first camera device 400 and the second camera are stationary, which has the characteristic of being easy to implement. Of course, in specific applications, as an alternative implementation scheme, the sample container 20 may also be used. The first camera device 400 and the second camera device are kept stationary and driven to rotate to find the target shooting direction. In this alternative implementation, the first rotation drive mechanism is not set, and the second rotation drive mechanism is set to drive the first camera device 400 and the second camera device to rotate horizontally around the axis MN perpendicular to the horizontal direction.

As an embodiment, the first rotation drive mechanism includes a first clamping component for clamping the sample container 20 and a rotation power component for driving the first clamping component to rotate, wherein the first clamping component is used to clamp the sample container 20, and the rotation power component is used to drive the first clamping component to rotate horizontally around an axis MN perpendicular to the horizontal direction. In this embodiment, the sample container 20 is driven to rotate by clamping the sample container 20, and its structure is simple and easy to implement; of course, in specific applications, other methods can also be used to drive the sample container 20 to rotate, for example, driving the bottom of the sample container 20 to rotate by a rotating seat.

As an embodiment, the sample analysis system 10 further includes a third camera device 700, which is used to perform a third shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered in a horizontal direction before the first camera device 400 performs the first shooting action on the sample container 20. The control device 500 is also configured to: obtain the height position of the interface liquid surface 321 or the interface liquid layer according to the image captured by the third camera device 700 when performing the third shooting action; and control the first camera device 400 to perform the first shooting action on the sample container 20 based on the height position of the interface liquid surface 321 or the interface liquid layer to obtain the first target image. Since the first camera device 400 has a requirement for the focus position when performing the first shooting action, before performing the first shooting action, the height position of the interface liquid surface 321 or the interface liquid layer is first found, and then the first shooting action is performed based on the height position, which is conducive to ensuring the clarity of the image of the interface liquid surface 321 or the interface liquid layer.

As an embodiment, the control device 500 is further configured to: before acquiring the first target image, first control the third camera device 700 to perform a third shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered, obtain the height position of the interface liquid surface 321 or the interface liquid layer according to the image captured by the third camera device 700 when performing the third shooting action, and obtain the target height position according to the height position of the interface liquid surface 321 or the interface liquid layer. The control device 500 obtains the first target image including: controlling one of the sample container 20 and the first camera device 400 to move relative to the other and stop at the target height position, controlling the first camera device 400 to perform the first shooting action on the sample container 20, and obtaining the first target image according to the image captured by the first camera device 400 when performing the first shooting action. The target height position can be a specific height position or a height range value. In this embodiment, the height position of the interface liquid surface 321 or the interface liquid layer is first found through the third shooting action, and the target height position for executing the first shooting action is obtained based on the height position of the interface liquid surface 321 or the interface liquid layer, which is beneficial to ensure that the first shooting action is based on the target height position and clearly captures the image of the interface liquid surface 321 or the interface liquid layer in two-dimensional form and/or three-dimensional form.

As an implementation mode, the third camera device 700 and the first camera device 400 are two independent camera devices, that is, the third camera device 700 and the first camera device 400 can be two different camera devices, so that the first camera device 400 and the third camera device 700 can work in parallel to simultaneously photograph two sample containers 20. In the above solution, the second camera device and the first camera device 400 are the same camera device. Of course, in a specific application, as an alternative implementation mode, the second camera device and the first camera device 400 can also be set as two independent camera devices, and the second camera device and the third camera device 700 can be set as the same camera device.

As an implementation mode, the control device 500 is further configured to: control the third camera device 700 to perform a third shooting action with a first field of view and a first object resolution; control the first camera device 400 to perform a first shooting action with a second field of view and a second object resolution, wherein the first field of view is larger than the second field of view, and the first object resolution is smaller than the second object resolution. The field of view is the maximum field of view that can be captured by the camera device. The object resolution refers to the minimum distance between two object points (or image points) that can be distinguished. In this implementation mode, the third shooting action is shot with a large field of view and a small object resolution, and the first shooting action is shot with a small field of view and a large object resolution. In this way, the third camera device 700 can capture an image used to characterize the height position of the interface liquid surface 321 or the interface liquid layer, and the first camera device 400 can clearly capture an image showing the interface liquid surface 321 or the interface liquid layer in a two-dimensional form and/or a three-dimensional form.

As an implementation manner, the third camera device 700 performs a third photographing operation on the sample container 20 along a horizontal direction, and the first camera device 400 performs a first photographing operation from an oblique direction above the intermediate layer liquid 32 .

As an implementation manner, the sample analysis system 10 further includes a first fill light component 800, which is used to emit light toward the sample container 20 in the first shooting action to illuminate the sample container 20. The first fill light component 800 can be disposed on the front or side of the sample container 20, or on the top or other positions of the sample container 20.

As an implementation, the second imaging device is a second camera, and the sample analysis system 10 further includes a second fill light component, which is used to emit light toward the sample container 20 in the second shooting action to illuminate the sample container 20. In this implementation, the first fill light component 800 and the second fill light component are the same component.

As an embodiment, the sample measuring device 200 includes a sample distribution mechanism 220 and a measuring mechanism 230. The sample distribution mechanism 220 is used to absorb at least a portion of the upper layer liquid 31 from the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and stratified into the upper layer liquid 31, the middle layer liquid 32, and the lower layer liquid 33, and distribute it to the reaction container; the measuring mechanism 230 is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid 31 and the reagent.

As an embodiment, the control device 500 is configured to: when the first sample container 20 loaded with the blood sample 30 and having a clot abnormality in the blood sample 30 is placed in the sample management device, control the sample container transfer device 300 to transfer the first sample container 20 loaded with the blood sample 30 and having a clot abnormality in the blood sample 30 The first sample container 20 after the blood sample 30 is centrifuged and separated into the upper layer liquid 31, the middle layer liquid 32, and the lower layer liquid 33 is transferred to the first shooting position, the first camera device 400 is controlled to perform the first shooting action on the first sample container 20 located at the first shooting position, and the sample container transfer device 300 is controlled to transfer the first sample container 20 after the first shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the first storage space. The blood sample 30 with abnormal clotting phenomenon includes at least one of the following situations: there is clotting in the blood sample 30 and the clotting meets the first preset condition, and the degree of coagulation of the blood sample 30 meets the second preset condition. The first storage space is used to recover the sample container 20 with abnormal clotting phenomenon. In the present embodiment, when a blood sample 30 with abnormal clotting phenomenon enters the sample analysis system 10, the control device 500 controls the sample container transmission device 300 to transmit the blood sample 30 that has been photographed by the first camera device 400 but has not been measured by the measuring mechanism 230 to the first storage space, that is, the blood sample 30 with abnormal clotting phenomenon will not be sent to the measuring mechanism 230, thereby effectively preventing the measuring mechanism 230 from measuring the blood sample 30 with abnormal clotting phenomenon, that is, the blood sample 30 with abnormal clotting phenomenon is intercepted, at least the time for the measuring mechanism 230 to measure the blood sample 30 with abnormal clotting phenomenon is saved, and thus it is beneficial to improve the sample measurement efficiency of the sample analysis system 10.

As an embodiment, the control device 500 is further configured to: when the second sample container 20 loaded with the blood sample 30 and having no abnormal clot phenomenon in the blood sample 30 is placed in the sample storage device 100, control the sample container transfer device 300 to transfer the second sample container 20 loaded with the blood sample 30 and having the blood sample 30 separated into the upper layer liquid 31, the middle layer liquid 32, and the lower layer liquid 33 after centrifugation to the first shooting position, control the first camera device 400 to perform a first shooting action on the second sample container 20 located at the first shooting position, control the sample container transfer device 300 to transfer the second sample container 20 after completing the first shooting action to the sample measurement device 200, control the sample distribution mechanism 220 to absorb at least part of the upper layer liquid 31 from the second sample container 20 and distribute it to the first reaction container, and control the measurement mechanism 230 to measure the first test liquid prepared by at least the upper layer liquid 31 distributed to the first reaction container and the reagent. The first sample container 20 and the second sample container 20 are two different sample containers 20, not the same sample container 20. The blood sample 30 without abnormal clotting phenomenon includes at least one of the following situations: there is no clot in the blood sample 30, there is clot in the blood sample 30 but the clot does not meet the first preset condition, and the degree of coagulation of the blood sample 30 does not meet the second preset condition. In this embodiment, when the blood sample 30 without abnormal clotting phenomenon enters the sample analysis system 10, the control device 500 controls the sample container transmission device 300 to transmit the second sample container 20 after completing the first shooting action to the sample measurement device 200, so that the sample distribution mechanism 220 and the measurement mechanism 230 normally aspirate and measure the blood sample 30 in the second sample container 20.

As an embodiment, the first storage space is located in the sample storage device 100. In this embodiment, the first storage space for recovering the sample container 20 with abnormal clotting phenomenon is set in the sample storage device 100, and the blood sample 30 with abnormal clotting phenomenon can be returned to the sample storage device 100 through the sample transmission device, so that the structure of the sample analysis system 10 can be used to realize the recovery function of the sample container 20 with abnormal clotting phenomenon, without the need to set up other components to recover the sample container 20 with abnormal clotting phenomenon, which can help simplify the structure of the sample analysis system 10 while satisfying the recovery function of the sample container 20 with abnormal clotting phenomenon. Of course, in specific applications, the setting method of the first storage space is not limited to this. For example, as an alternative embodiment, the first storage space is located beside the sample container transmission device 300, that is, the first storage space is located on the side or horizontal side of the sample transmission device, and the blood sample 30 with abnormal clotting phenomenon can be transferred to the first storage space by track transmission or manipulator. Alternatively, as another alternative embodiment, the first storage space is located below the sample container transport device 300, and the sample container transport device 300 is provided with a recovery port connected to the first storage space, and the blood sample 30 with abnormal clotting phenomenon can be transferred to the recovery port by rail transport or robot. Alternatively, as another alternative embodiment, the first storage space is located above the sample container transport device 300, and the blood sample 30 with abnormal clotting phenomenon can be transferred to the first storage space by robot.

As an implementation mode of setting up the first storage space, the sample storage device 100 is provided with a loading area, a recovery area and a first abnormal area. The loading area is used for placing the sample container 20 to realize the loading of the sample container 20. The recovery area is used for placing the sample container 20 that has been measured by the sample measuring device 200 and the measurement result of the blood sample 30 loaded therein is determined to be normal to realize the recovery of the sample container 20. The first abnormal area is used at least to store the sample container 20 with abnormal code scanning, the sample container 20 with abnormal measurement result of the blood sample 30 loaded therein that has been measured by the sample measuring device 200 and the measurement result of the blood sample 30 loaded therein is determined to be abnormal, and the sample container 20 with abnormal clot phenomenon in the blood sample 30 loaded therein determined by taking an image by the first camera device 400. The first storage space is located in the first abnormal area. In this embodiment, the first abnormal area in the sample storage device 100 for storing sample containers 20 with abnormal code scanning and sample containers 20 with abnormal blood sample 30 measured by the sample measuring device 200 is reused as the first storage space to store sample containers 20 with abnormal clots in the blood sample 30 measured by the first camera 400. In this way, it is not necessary to set up other structures to form the first storage space, and the structure is simple. Specifically, the sample measuring device 200 also includes an identification component, which is used to identify the identification code on the sample container 20 before the sample distribution mechanism 220 draws the upper layer of liquid 31 from the sample container 20, that is, to scan the sample container 20. The identification code on the sample container 20 can be a barcode, a two-dimensional code, a wireless radio frequency code, etc., and the identification component can be a scanner or a visual camera. As a further embodiment, the second storage space described below for storing blood samples 30 with any abnormal phenomenon of abnormal liquid volume, abnormal hematocrit, and abnormal HIL can also be located in the first abnormal area.

Alternatively, as another embodiment of the first storage space setting method, the sample storage device 100 is provided with a loading area, a recovery area, a first abnormal area and a second abnormal area. The loading area is used for placing the sample container 20 to load the sample container 20, and the recovery area is used for placing the sample container 20 after being loaded. The sample container 20 that has been tested by the sample measuring device 200 and the test result of the blood sample 30 loaded therein is determined to be normal is used to realize the recovery of the sample container 20. The first abnormal area is used to store the sample container 20 with abnormal code scanning and the sample container 20 with abnormal test result of the blood sample 30 loaded therein after the sample measuring device 200 has been tested. The second abnormal area is used to place the sample container 20 with abnormal clot phenomenon in the blood sample 30 loaded therein after the first camera device 400 takes an image. The first storage space is located in the second abnormal area. In this embodiment, the second abnormal area is separately set in the sample storage device 100 as the first storage space to store the sample container 20 with abnormal clot phenomenon in the blood sample 30 loaded therein after the first camera device 400 takes an image, instead of directly using the first abnormal area in the sample storage device 100 for storing the sample container 20 with abnormal code scanning and the sample container 20 with abnormal test result of the blood sample 30 loaded therein after the sample measuring device 200 has been tested. This is conducive to the zoning management of different abnormal sample containers 20. As a further embodiment, the second storage space is located in the first abnormal area or the second abnormal area or an area different from the first abnormal area and different from the second abnormal area.

Alternatively, as another embodiment of the first storage space setting method, the sample storage device 100 is provided with a loading area, a recovery area, a first abnormal area, a second abnormal area and a third abnormal area. The loading area is used for placing the sample container 20 to realize the loading of the sample container 20. The recovery area is used to place the sample container 20 that has been measured by the sample measuring device 200 and the measurement result of the blood sample 30 loaded therein is determined to be normal to realize the recovery of the sample container 20. The first abnormal area is used to store the sample container 20 with abnormal code scanning. The second abnormal area is used to place the sample container 20 with abnormal clot phenomenon in the blood sample 30 loaded therein determined by the first camera device 400. The third abnormal area is used to place the sample container 20 that has been measured by the sample measuring device 200 and the measurement result of the blood sample 30 loaded therein is determined to be abnormal. The first storage space is located in the second abnormal area. In this embodiment, a second abnormal area is separately set in the sample storage device 100 as the first storage space to store sample containers 20 whose blood samples 30 are judged to have abnormal clot phenomenon by the first camera device 400, and sample containers 20 with abnormal code scanning and sample containers 20 with abnormal blood samples 30 are also placed in different areas, which is conducive to further refined zoning management of different abnormal sample containers 20. As a further embodiment, the second storage space is located in the first abnormal area, the second abnormal area, the third abnormal area, or an area different from the first abnormal area, the second abnormal area, and the third abnormal area.

Alternatively, as another embodiment of the first storage space setting method, the sample storage device 100 is provided with a loading area, a recovery area and a first abnormal area. The loading area is used for placing the sample container 20 to realize the loading of the sample container 20. The recovery area is used to place the sample container 20 that has been measured by the sample measuring device 200 and the measurement result of the blood sample 30 loaded therein is determined to be normal to realize the recovery of the sample container 20. The first abnormal area is at least used to store the sample container 20 with abnormal code scanning and the sample container 20 that has been measured by the sample measuring device 200 and the measurement result of the blood sample 30 loaded therein is determined to be abnormal. The sample analysis system 10 also includes a recovery container, which is located outside the sample storage device 100, and the recovery container is located beside, below or above the sample container transmission device 300. The recovery container is used to place the sample container 20 that has been determined by the first camera device 400 to have abnormal clot phenomenon in the blood sample 30 loaded therein, and the first storage space is located in the recovery container. In this embodiment, a recovery container is additionally provided outside the sample storage device 100 to form a first storage space, so that the recovery and processing of the blood sample 30 with abnormal clotting phenomenon will not affect the sample storage device 100. As a further embodiment, the second storage space is located in the first abnormal area or the recovery container or an area different from the first abnormal area and different from the recovery container.

As an embodiment, the above-mentioned controlling the sample container transporting device 300 to transport the first sample container 20 after the first shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the first storage space includes: according to the image obtained by the first camera device 400 performing the first shooting action on the first sample container 20 located at the first shooting position, controlling the sample container transporting device 300 to transport the first sample container 20 after the first shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the first storage space. In this embodiment, the control device 500 controls the sample container transporting device 300 to transport the blood sample 30 with abnormal clot phenomenon to the first storage space according to the image of the sample container 20 captured by the first camera device 400, that is, the image of the sample container 20 captured by the first camera device 400 is used as the basis for the control device 500 to determine whether to control the sample container transporting device 300 to transfer the blood sample 30 to the first storage space.

As an embodiment, the above-mentioned control of the sample container transmission device 300 to transmit the first sample container 20 located at the first shooting position after the first shooting action is completed and the upper layer liquid 31 thereof has not been measured by the measuring mechanism 230 to the first storage space according to the image obtained by the first camera device 400 performing the first shooting action on the first sample container 20 located at the first shooting position includes: obtaining a first target image according to information fed back by the first camera device 400 performing the first shooting action on the first sample container 20 located at the first shooting position; when it is determined according to the first target image that the blood sample 30 loaded in the first sample container 20 has an abnormal clot phenomenon, the sample container transmission device 300 is controlled to transmit the first sample container 20 located at the first shooting position after the first shooting action is completed and the upper layer liquid 31 thereof has not been measured by the measuring mechanism 230 to the first storage space. In this embodiment, the control device 500 can analyze the first target image obtained by the first camera device 400 shooting the sample container 20 to determine whether the blood sample 30 loaded in the sample container 20 has an abnormal clot phenomenon. When it is determined that the blood sample 30 loaded in the first sample container 20 has an abnormal clot phenomenon according to the first target image, the sample container transmission device 300 is controlled to transmit the blood sample 30 with the abnormal clot phenomenon to the first storage space. That is, the node at which the control device 500 controls the sample container transmission device 300 to transmit the blood sample 30 with the abnormal clot phenomenon to the first storage space is located after it is determined that the blood sample 30 loaded in the first sample container 20 has an abnormal clot phenomenon according to the first target image.

As an implementation manner, the first camera device 400 is controlled to perform a first shooting action on the second sample container 20 located at the first shooting position. After the operation, and before controlling the measuring mechanism 230 to measure the first liquid to be tested made of at least the upper layer liquid 31 and the reagent distributed in the first reaction container, the control device 500 is further configured to: obtain a first target image according to the information fed back by the first camera device 400 performing the first shooting operation on the second sample container 20 located at the first shooting position; and determine that the blood sample 30 loaded in the second sample container 20 has no abnormal clot according to the first target image. In this embodiment, the control device 500 determines that the blood sample 30 loaded in the second sample container 20 has no abnormal clot according to the first target image, and then controls the measuring mechanism 230 to measure the first liquid to be tested made of at least the upper layer liquid 31 and the reagent distributed in the first reaction container. That is, the node at which the control device 500 controls the measuring mechanism 230 to measure the first liquid to be tested made of at least the upper layer liquid 31 and the reagent distributed in the first reaction container is located after determining that the blood sample 30 loaded in the second sample container 20 has no abnormal clot according to the first target image.

As an implementation mode, the above-mentioned determination of the presence of abnormal clots in the blood sample 30 loaded in the first sample container 20 according to the first target image is mainly based on algorithmic judgment of the buffy coat layer image. The specific algorithmic judgment method can be based on checking and judging whether the buffy coat layer is flat, or can be analyzed and judged by AI algorithms such as CNN convolutional neural network and other methods.

As an embodiment, judging that the blood sample 30 loaded in the first sample container 20 has abnormal clotting phenomenon according to the first target image includes: extracting the target index used to characterize the flatness of the intermediate layer liquid 32 in the first target image; comparing the target index with the preset index; if the target index is greater than or equal to the preset index, judging that the blood sample 30 loaded in the first sample container 20 has abnormal clotting phenomenon. It has been found through research that after centrifugation, the intermediate liquid layer of a normal blood sample 30 (blood sample 30 without abnormal clotting phenomenon) is very flat; while the blood sample 30 with abnormal clotting phenomenon is manifested as an uneven intermediate liquid layer (sometimes manifested as uneven intermediate liquid layer, sometimes manifested as a layer of loose floating objects coagulated by fibrin on the intermediate liquid layer, which is mainly caused by different sizes, causes and time of formation of clots). The main reason for the unevenness of the middle liquid layer of the blood sample 30 with abnormal coagulation is that, for example, when the blood sample 30 and the anticoagulant are not mixed well, the blood sample 30 has already coagulated before centrifugation. The main mechanism of coagulation is that the fibrinogen in the plasma forms fibrin under the action of a series of coagulation factors, and the fibrin will wrap the blood cells to form a clot. After centrifugation, if the density of the clot is between that of red blood cells and plasma, the clot is near the middle liquid layer, which will cause the unevenness of the middle liquid layer. In addition, some parts of the formed clots wrap more platelets, while some parts wrap more red blood cells, so the density of the clots at different positions is different, which is also one of the reasons why the clots cause the unevenness of the middle liquid layer. In this embodiment, the target index of the white film layer image (i.e., the first target image) obtained by capturing is used to characterize the flatness of the white film layer (for example, the number and/or size of the concave-convex structures used to characterize the flatness of the white film layer), and the target index is compared with a preset index. When the target index is higher than the preset index, it is determined that the blood sample 30 has abnormal clotting phenomenon, otherwise it is determined that the blood sample 30 has no abnormal clotting phenomenon.

Of course, in specific applications, it is not limited to analyzing the buffy coat image by target indicators to determine whether the blood sample 30 has abnormal clotting phenomenon. For example, as an alternative embodiment, the above-mentioned determination of the presence of abnormal clotting phenomenon in the blood sample 30 loaded in the first sample container 20 based on the first target image includes: extracting target features in the first target image; comparing the target features with preset features; if the similarity between the target features and the preset features is greater than or equal to a first preset threshold, then determining that the blood sample 30 loaded in the first sample container 20 has abnormal clotting phenomenon. In this alternative embodiment, based on target feature detection (for example, features for characterizing clots), by extracting the target features in the captured buffy coat image (i.e., the first target image), and comparing the target features with the preset features, when the similarity or matching degree between the target features and the preset features reaches the first preset threshold, then determining that the blood sample 30 has abnormal clotting phenomenon, otherwise determining that the blood sample 30 has no abnormal clotting phenomenon.

Alternatively, as another alternative embodiment, the above-mentioned determination of the presence of abnormal clotting phenomenon in the blood sample 30 loaded in the first sample container 20 according to the first target image includes: comparing the first target image with a preset image; if the similarity between the first target image and the preset image is greater than or equal to a second preset threshold, determining that the blood sample 30 loaded in the first sample container 20 has abnormal clotting phenomenon. In this alternative embodiment, by pre-storing one or more preset images with abnormal clotting phenomenon in the sample analysis system 10, the entire buffy coat layer image (i.e., the first target image) obtained by shooting is directly compared with the preset image pre-stored in the sample analysis system 10, and when the similarity or matching degree between the obtained buffy coat layer image and the preset image reaches the second preset threshold, it is determined that the blood sample 30 has abnormal clotting phenomenon.

As an embodiment, the first camera device 400 is used to perform a first shooting action on the sample container 20 from the oblique upper or oblique lower side of the intermediate layer liquid 32 loaded in the sample container 20 before the sample measuring device 200 draws the upper layer liquid 31 from the sample container 20. The first camera device 400 shoots the liquid surface image of the buffy coat layer from the oblique upper or oblique lower side of the intermediate layer liquid 32 loaded in the sample container 20, which helps to ensure that the two-dimensional liquid surface image and/or three-dimensional liquid surface image of the buffy coat layer, i.e., the two-dimensional and/or three-dimensional image of the interface liquid surface 321 or the interface liquid layer, is captured. The control device 500 can identify abnormalities in the buffy coat layer image, and if the buffy coat layer image of the blood sample 30 is abnormal, it is considered that the blood sample 30 has a clot abnormality.

As an embodiment, the sample measuring device 200 further includes a reagent dispensing mechanism 250 , and the reagent dispensing mechanism 250 is used to dispense the reagent into the reaction container.

As an embodiment, the sample measuring device 200 further includes an incubation mechanism 240 , and the incubation mechanism 240 is used to incubate the liquid in the reaction container including at least the upper layer liquid 31 .

As an embodiment, the control device 500 controls the sample container transmission device 300 to transmit the first sample container 20 loaded with the blood sample 30 and having the abnormal clot phenomenon of the blood sample 30 to the node of the first storage space, where the control device 500 controls the sample container transmission device 300 according to the first target image. After determining that the blood sample 30 loaded in the first sample container 20 has a clotting abnormality. Since the control device 500 needs time to analyze the first target image to determine that the blood sample 30 loaded in the first sample container 20 has a clotting abnormality after the first camera device 400 completes the first shooting action on the first sample container 20, when the control device 500 completes the analysis of the first target image and determines that the blood sample 30 loaded in the first sample container 20 has a clotting abnormality, the first sample container 20 may be in one of the following nodes: 1) It has not been transferred to the sample measuring device 200 by the sample container transfer device 300; 2) It has been transferred to the sample measuring device 200 by the sample container transfer device 300, but the sample measuring device 200 has not yet sucked the sample from the first sample container 20; 3) It has been transferred to the sample measuring device 200 by the sample container transfer device 300, and the sample measuring device 200 has been The sample has been drawn from the first sample container 20 and distributed to the reaction container, but the sample measuring device 200 has not yet distributed the reagent to the reaction container containing the blood sample 30; 4) It has been transferred to the sample measuring device 200 by the sample container transfer device 300, and the sample measuring device 200 has drawn from the first sample container 20 and distributed to the reaction container, but the sample measuring device 200 has not yet incubated the reaction container containing the blood sample 30; 5) It has been transferred to the sample measuring device 200 by the sample container transfer device 300, and the sample measuring device 200 has drawn from the first sample container 20 and distributed to the reaction container, and has distributed the reagent to the reaction container containing the blood sample 30 and incubated the reaction container, but the measuring mechanism 230 has not yet measured the test liquid in the reaction container made of at least the blood sample 30 and the reagent. Since at these nodes, the measuring mechanism 230 has not yet measured the blood sample 30 with the abnormal clotting phenomenon, the control device 500 completes the analysis of the first target image at these nodes and determines that the blood sample 30 loaded in the first sample container 20 has the abnormal clotting phenomenon, and controls the sample container transfer device 300 to transfer the blood sample 30 with the abnormal clotting phenomenon to the first storage space, which can effectively prevent the measuring mechanism 230 from measuring the blood sample 30 with the abnormal clotting phenomenon, thereby at least saving the time for the measuring mechanism 230 to measure the blood sample 30 with the abnormal clotting phenomenon, and further helping to improve the sample measurement efficiency of the sample analysis system 10.

As an embodiment, the above-mentioned controlling the sample container transporting device 300 to transport the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 thereof is measured by the measuring mechanism 230 to the first storage space includes: controlling the sample container transporting device 300 to transport the first sample container 20 after completing the first shooting action and before the sample container transporting device 300 is transported to the sample measuring device 200 by the sample container transporting device 300 to the first storage space. In this embodiment, the node at which the control device 500 completes the analysis of the first target image and determines whether the blood sample 30 loaded in the first sample container 20 has a coagulation abnormality may be, for example, before the first sample container 20 is transported to the sample measuring device 200 by the sample container transporting device 300, when the first sample container 20 is still in the first shooting position, or when the first sample container 20 is located on the way of being transported toward the sample measuring device 200 by the sample container transporting device 300, or when the first sample container 20 is placed in a cache position after completing the first shooting action to wait for the conclusion of the control device 500 determining whether the blood sample 30 loaded in the first sample container 20 has a coagulation abnormality. Since the blood sample 30 with abnormal clotting phenomenon has a node that is rolled back before the blood sample 30 is transmitted to the sample measuring device 200, that is, after the blood sample 30 with abnormal clotting phenomenon is photographed by the first camera device 400, it will not be transmitted to the sample measuring device 200, but will be transmitted to the first storage space for recovery. In this way, the sample measuring device 200 will not perform the sample suction action, reagent addition action, incubation action and measurement action on the blood sample 30 with abnormal clotting phenomenon, which is beneficial to reduce the waste of consumables such as reaction containers and reagents, and avoid the blood sample 30 from occupying the resources of the sample measuring device 200, thereby improving the measurement efficiency of batch blood samples 30.

Alternatively, as another embodiment, the above-mentioned controlling the sample container transporting device 300 to transport the first sample container 20 after the first shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the first storage space includes: controlling the sample container transporting device 300 to transport the first sample container 20 after the first shooting action is completed to the sample measuring device 200, and controlling the sample container transporting device 300 to transport the first sample container 20 output from the sample measuring device 200 and the upper layer liquid 31 has not been sucked out of it by the sample dispensing mechanism 220 to the first storage space. In this embodiment, the node at which the control device 500 completes the analysis of the first target image and determines that the blood sample 30 loaded in the first sample container 20 has a clot abnormality phenomenon, before the sample measuring device 200 sucks the sample from the first sample container 20, for example, can be the first sample container 20 in the loading area or buffer area of the sample measuring device 200 or the sample suction and delivery channel 210 or the sample suction position. Since the blood sample 30 with abnormal clotting phenomenon has a node that is retracted, it is located before the sample measuring device 200 aspirates the sample from the first sample container 20, that is, the blood sample 30 with abnormal clotting phenomenon will be transmitted to the sample measuring device 200 after the first camera device 400 completes the shooting, but will not be aspirated and measured by the sample measuring device, but will be transmitted to the first storage space for recovery before aspirating the sample. In this way, the sample measuring device 200 will not perform aspirating, reagent adding, incubating and measuring actions on the blood sample 30 with abnormal clotting phenomenon, which is beneficial to reducing the waste of consumables such as reaction containers and reagents, and avoiding the occupation of resources of the sample measuring device 200 by the blood sample 30, thereby improving the measurement efficiency of batch blood samples 30.

Alternatively, as another embodiment, the above-mentioned control of the sample container transport device 300 to transport the first sample container 20 after the first shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the first storage space includes: controlling the sample container transport device 300 to transport the first sample container 20 after the first shooting action is completed to the sample measuring device 200, controlling the sample dispensing mechanism 220 to absorb at least part of the upper layer liquid 31 from the first sample container 20 and distribute it to the second reaction container, and controlling the sample container transport device 300 to transport the first sample container 20 output from the sample measuring device 200 and before the reagent dispensing mechanism 250 distributes the reagent to the second reaction container to the first storage space. In this embodiment, the control device 500 completes the analysis of the first target image and determines the node where the blood sample 30 loaded in the first sample container 20 has a clot abnormality, before the reagent dispensing mechanism 250 distributes the reagent to the second reaction container, for example, The second reaction container may be after the sample loading is completed at the loading position or the second reaction container after the sample loading is in the process of being transferred to the incubation mechanism 240 or the second reaction container after the sample loading is on the incubation mechanism 240 or the second reaction container after the sample loading is in the process of being transferred to the reagent loading position or the second reaction container after the sample loading is located at the reagent loading position. For the blood sample 30 with abnormal clotting phenomenon, the node to be returned is located before the sample measuring device 200 distributes the reagent to the second reaction container, that is, after the blood sample 30 with abnormal clotting phenomenon is photographed by the first camera device 400, it will be transferred to the sample measuring device 200 for sample suction, but the action of adding reagent and measuring will not be performed after the sample suction, but it will be transferred to the first storage space for recycling before adding reagent, so that the sample measuring device 200 will not perform the action of adding reagent and measuring on the blood sample 30 with abnormal clotting phenomenon, which is beneficial to reduce the waste of reagent and avoid the occupation of resources of the sample measuring device 200 by the blood sample 30, thereby improving the measurement efficiency of batch blood samples 30.

Alternatively, as yet another embodiment, controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action and without the upper layer liquid 31 loaded therein being measured by the measuring mechanism 230 to the first storage space includes: controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action to the sample measuring device 200, controlling the sample dispensing mechanism 220 to absorb at least a portion of the upper layer liquid 31 from the first sample container 20 and distribute it to the second reaction container, and controlling the sample container transmission device 300 to transmit the first sample container 20 output from the sample measuring device 200 and without the incubation mechanism 240 to incubate the liquid in the second reaction container at least containing the upper layer liquid 31 distributed from the first sample container 20 to the second reaction container to the first storage space. In this embodiment, the control device 500 completes the analysis of the first target image and determines the node where the blood sample 30 loaded in the first sample container 20 has an abnormal clotting phenomenon, before the incubation mechanism 240 incubates the liquid in the second reaction container containing at least the upper liquid 31, for example, the second reaction container may be after the sample is loaded at the loading position or the second reaction container after the sample is loaded is on the way to the incubation mechanism 240 or the second reaction container after the sample is loaded is on the incubation mechanism 240. Since the blood sample 30 with abnormal clotting phenomenon has a node that is retracted, it is located before the sample measuring device 200 incubates the liquid in the second reaction container, that is, after the blood sample 30 with abnormal clotting phenomenon is photographed by the first camera device 400, it will be transmitted to the sample measuring device 200 for sample aspiration, but no incubation and measurement will be performed after sample aspiration. Instead, it will be transmitted to the first storage space for recovery before incubation. In this way, the sample measuring device 200 will not perform incubation and measurement actions on the blood sample 30 with abnormal clotting phenomenon, which is beneficial to avoid the blood sample 30 occupying the resources of the sample measuring device 200, thereby helping to improve the measurement efficiency of batch blood samples 30.

Alternatively, as another embodiment, controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space includes: controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action to the sample measuring device 200, controlling the sample dispensing mechanism 220 to absorb at least a portion of the upper layer liquid 31 from the first sample container 20 and distribute it to the second reaction container, controlling the incubation mechanism 240 to incubate the liquid in the second reaction container at least containing the upper layer liquid 31 distributed from the first sample container 20 to the second reaction container, controlling the reagent dispensing mechanism 250 to distribute the reagent to the second reaction container, and controlling the sample container transmission device 300 to transmit the first sample container 20 output from the sample measuring device 200 and before the second liquid to be tested containing at least the upper layer liquid 31 distributed to the second reaction container and the reagent to the second reaction container to the first storage space. In this embodiment, the control device 500 completes the analysis of the first target image and determines the node where the blood sample 30 loaded in the first sample container 20 has the abnormal clotting phenomenon, before the measuring mechanism 230 measures the second test liquid in the second reaction container at least including the upper layer liquid 31 and the reagent, for example, after the second reaction container has completed the reagent addition at the reagent adding position or during the process of the second reaction container after the reagent addition being transferred to the measuring mechanism 230 or the second reaction container is on the incubation mechanism 240. Since the blood sample 30 with the abnormal clotting phenomenon is returned to the node before the sample measuring device 200 measures the liquid in the second reaction container, the sample measuring device 200 will not perform the measuring action on the blood sample 30 with the abnormal clotting phenomenon, which is conducive to avoiding the occupation of the resources of the sample measuring device 200 by the blood sample 30, thereby facilitating the improvement of the measuring efficiency of the batch blood samples 30.

As an embodiment, when a first sample container 20 loaded with a blood sample 30 and in which a clotting abnormality exists is placed in the sample storage device 100, after controlling the first camera device 400 to perform a first shooting action on the first sample container 20 located at the first shooting position, the control device 500 is further configured to: output prompt information for characterizing that the blood sample 30 in the first sample container 20 has a clotting abnormality, so as to help remind the operator to intervene in the processing of the blood sample 30 with the clotting abnormality, for example: manually review whether the blood sample 30 actually has a clotting abnormality, and when it is determined that a clotting abnormality exists, the blood sample 30 can be collected from the patient again or the blood sample 30 can be processed to eliminate the clot, etc.

As an embodiment, the output of the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon is performed after the control device 500 completes the analysis of the first target image and determines that the blood sample 30 loaded in the first sample container 20 has an abnormal clot phenomenon. That is, when the first sample container 20 loaded with the blood sample 30 and the blood sample 30 having an abnormal clot phenomenon is placed in the sample storage device 100, after the control device 500 completes the analysis of the first target image and determines that the blood sample 30 loaded in the first sample container 20 has an abnormal clot phenomenon, the control device 500 is further configured to output the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon.

As an embodiment, the output is used to indicate that the blood sample 30 in the first sample container 20 has a clot abnormality. When the sample container transmission device 300 is controlled to complete the first shooting action and the upper layer of liquid loaded by the measuring mechanism 230 is The control device 500 is further configured to output prompt information indicating that the blood sample 30 in the first sample container 20 has abnormal clotting phenomenon. In this embodiment, the prompt information indicating that the blood sample 30 in the first sample container 20 has abnormal clotting phenomenon is outputted after the sample container transfer device 300 transfers the first sample container 20 loaded with the blood sample 30 having abnormal clotting phenomenon to the first storage space. In this way, the operator can quickly process the first sample container 20 loaded with the blood sample 30 having abnormal clotting phenomenon according to the prompt information.

Of course, in a specific application, outputting the prompt information for indicating that the blood sample 30 in the first sample container 20 has a coagulation abnormality is not limited to being executed after the blood sample 30 with the coagulation abnormality is transferred to the first storage space. For example, as an alternative embodiment, in the process of controlling the sample container transfer device 300 to transfer the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space, the control device 500 is further configured to: output the prompt information for indicating that the blood sample 30 in the first sample container 20 has a coagulation abnormality; or, as another alternative embodiment, after controlling the first camera device 400 to perform the first shooting action on the first sample container 20 located at the first shooting position, and before controlling the sample container transfer device 300 to transfer the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space, the control device 500 is further configured to: output the prompt information for indicating that the blood sample 30 in the first sample container 20 has a coagulation abnormality. Specifically, the control device 500 is also configured to: output prompt information for characterizing the presence of abnormal clotting phenomenon in the blood sample 30 in the first sample container 20 at one of the following nodes: after controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space; during the process of controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space; after controlling the first camera device 400 to perform the first shooting action on the first sample container 20 located at the first shooting position, and before controlling the sample container transmission device 300 to transmit the first sample container 20 after completing the first shooting action and before the upper layer liquid 31 loaded therein is measured by the measuring mechanism 230 to the first storage space. That is, after controlling the first camera device 400 to perform the first shooting action on the first sample container 20 located at the first shooting position, after the sample container transmission device 300 transmits the first sample container 20 to the first storage space, or before the sample container transmission device 300 transmits the first sample container 20 to the first storage space, or during the process of the sample container transmission device 300 transmitting the first sample container 20 to the first storage space, a prompt message for indicating that there is an abnormal clot phenomenon in the blood sample 30 in the first sample container 20 can be output.

As an embodiment, the sample analysis system 10 further includes a first display 101, the first display 101 and the sample measuring device 200 are independently arranged, the first display 101 is used to display at least the storage information of the blood sample 30 in the sample storage device 100 and the information of the blood sample 30 transmitted by the sample container transmission device 300, and outputting the prompt information for indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon includes: controlling the first display 101 to display the prompt information for indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon. In this embodiment, the sample analysis system 10 is a sample analysis pipeline or a sample analysis cascade system, and the sample analysis system 10 includes at least two sample measuring devices 200, and the at least two sample measuring devices 200 are respectively connected to the sample container transmission device 300. The first display 101 is a display at the operation end of the sample analysis pipeline or the sample analysis cascade system. The prompt information indicating that the blood sample 30 in the first sample container 20 has abnormal clotting phenomenon is set to be displayed on the first display 101, so that the operator can more conveniently and quickly obtain the prompt information and process the blood sample 30 with abnormal clotting phenomenon.

In a specific application, the output of the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon can also be displayed on other displays. For example, as an embodiment, the sample measuring device 200 further includes a second display, which is used to display at least the measurement item information of the blood sample 30 in the sample measuring device 200. The output of the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon includes: controlling the second display to display the prompt information indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon. The second display is a display provided by the sample measuring device 200, that is, a display of a stand-alone sample analyzer.

Alternatively, as another embodiment, the above-mentioned output of the prompt information for characterizing the presence of abnormal clotting phenomenon in the blood sample 30 in the first sample container 20 includes: transmitting the prompt information for characterizing the presence of abnormal clotting phenomenon in the blood sample 30 in the first sample container 20 to a laboratory information management system (i.e., LIS system) that is communicatively connected to the sample analysis system 10.

Alternatively, as another embodiment, the sample analysis system 10 further includes an alarm device, the alarm device includes a sound alarm component and/or a light alarm component, and outputting the prompt information for indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon includes: controlling the alarm device to issue a sound alarm signal and/or a light alarm signal for indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon. That is, the prompt information for indicating that the blood sample 30 in the first sample container 20 has an abnormal clot phenomenon can be issued through a sound alarm or a light alarm signal.

As an implementation manner, the first display 101 is located beside the sample storage device 100 or beside the sample container transmission device 300 .

As an embodiment, the control device 500 is further configured to: control the first display 101 to display the first target image and the second target image. The image is displayed, thereby facilitating the operator to review the quality information of the blood sample 30, thereby improving the intuitiveness and efficiency of the review.

As an implementation manner, the control device 500 is further configured to: control the first display 101 to display the first target image and the second target image on the same interface.

As an embodiment, the control device 500 is further configured to: control the first display 101 to display the first target image, the second target image, the hematocrit test result, the clot test result, the fluid volume test result, the hemolysis test result, the jaundice test result and the lipemia test result on the same interface. In this way, it is helpful to reduce the time for the operator to find the relevant information of the quality test of the blood sample 30, and further help to improve the intuitive and rapid judgment or review of the quality of the blood sample 30, and finally help to improve the efficiency of the quality review of the blood sample 30.

As an embodiment, the control of the sample container transport device 300 to transport the first sample container 20 after the first shooting action is completed and the upper layer liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the first storage space includes: controlling the sample container transport device 300 to transport the first sample container 20 to the first storage space along a first route. The control of the sample container transport device 300 to transport the second sample container 20 after the first shooting action is completed to the sample measuring device 200 includes: controlling the sample container transport device 300 to transport the second sample container 20 to the sample measuring device 200 along a second route; wherein the first route and the second route are at least partially different. In the present embodiment, after the control device 500 completes the analysis of the first target image and draws a conclusion on whether the blood sample 30 loaded in the sample container 20 has the abnormal clotting phenomenon, the blood sample 30 with the abnormal clotting phenomenon and the blood sample 30 without the abnormal clotting phenomenon are respectively transmitted along different routes, wherein the blood sample 30 with the abnormal clotting phenomenon is transmitted along one route toward the first storage space, and the blood sample 30 without the abnormal clotting phenomenon is transmitted along another route toward the sample measuring device 200, thereby facilitating the recovery and processing of the blood sample 30 with the abnormal clotting phenomenon and the sampling and measurement of the blood sample 30 without the abnormal clotting phenomenon.

As an embodiment, the third camera device 700 is used to perform a third shooting action on the sample container 20 before the sample dispensing mechanism 220 absorbs at least part of the upper layer of liquid 31 from the sample container 20. The control device 500 is also configured to: obtain a third target image according to the information fed back by the third camera device 700 when performing the third shooting action; obtain at least one of the following information according to the third target image: the total liquid volume of the blood sample 30 in the sample container 20, the hematocrit of the blood sample 30 in the sample container 20, the hemolysis index of the blood sample 30 in the sample container 20, the icteric index of the blood sample 30 in the sample container 20, and the lipemia index of the blood sample 30 in the sample container 20. The hematocrit is also called the packed cell volume, that is, HCT. The hemolysis index, the icteric index, and the lipemia index can be collectively referred to as HIL. In this embodiment, at least one of the hematocrit test result, the liquid volume test result, the hemolysis test result, the icteric test result, and the lipemia test result is obtained through the third target image, and the detection method is simple. As an embodiment, the control device 500 is also configured to obtain at least two of the following information based on the third target image: the total liquid volume of the blood sample 30 in the sample container 20, the hematocrit of the blood sample 30 in the sample container 20, the hemolytic index of the blood sample 30 in the sample container 20, the icterus index of the blood sample 30 in the sample container 20, and the lipemia index of the blood sample 30 in the sample container 20.

As an embodiment, the control device 500 is also configured to obtain all of the following information based on the third target image: the total liquid volume of the blood sample 30 in the sample container 20, the hematocrit of the blood sample 30 in the sample container 20, the hemolytic index of the blood sample 30 in the sample container 20, the icterus index of the blood sample 30 in the sample container 20, and the lipemia index of the blood sample 30 in the sample container 20.

As an embodiment, the third target image at least includes an image showing the entire height of one side of the sample container 20 in a two-dimensional and/or three-dimensional form, or at least includes an image showing the entire blood sample 30 in the sample container 20 in a two-dimensional and/or three-dimensional form, or at least includes an image showing the liquid surface of the upper liquid 31, the liquid surface of the middle layer liquid 32, and the liquid surface of the lower layer liquid 33 in the sample container 20, or at least includes an image showing the entire upper liquid 31, the entire middle layer liquid 32, and the entire lower layer liquid 33 in the sample container 20 in a two-dimensional and/or three-dimensional form, or at least includes an image showing at least one side of the bottom, middle part, and top of the sample container 20 in a two-dimensional and/or three-dimensional form. The third target image is a full-view image of the sample container 20 (it may be a full-view image of the sample container 20 with a cap, or it may be a full-view image of the sample container 20 without a cap, or it may be a full-view image of the sample container 20 with a stopper, or it may be a full-view image of the sample container 20 without a stopper), which may at least display the entire height information of the sample container 20; or the third target image is a full-view image of the blood sample 30 in the sample container 20, which may at least display the height information of the three liquid levels of the blood sample 30 in the sample container 20 or the entire height information. For the convenience of description and understanding, the third target image may also be referred to as a full-view image of the blood sample 30.

As an implementation manner, the third camera device 700 and the first camera device 400 are two independent camera devices, that is, the third camera device 700 and the first camera device 400 are two different camera devices, rather than the same camera device. In this implementation manner, by setting two camera devices, one of which is used to capture the full image of the blood sample 30, and the other is used to capture the white film layer image of the blood sample 30, the full image of one blood sample 30 and the white film layer image of another blood sample 30 can be captured in parallel, thereby facilitating the improvement of the detection efficiency of batch blood samples 30. Of course, in a specific application, as an alternative implementation manner, the third camera device 700 and the first camera device 400 can also be set as the same camera device.

As an implementation manner, the first camera device 400 and the third camera device 700 are respectively located at two different positions. Of course, in a specific application, as an alternative implementation manner, the first camera device 400 and the third camera device 700 can also be located at the same position.

As an embodiment, the third camera device 700 is located in front of the first camera device 400 along the transmission direction of the sample container 20. The sample container 20 is first transmitted to the shooting position of the third camera device 700 for shooting, and then transmitted to the shooting position of the first camera device 400 for shooting.

As an embodiment, the third camera device 700 is used to capture the sample container 20 after the first camera device 400 performs the first capturing action. Before the third camera 700 is used, the third shooting action is performed in the horizontal direction on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered, that is, the third camera device 700 is used to shoot the image of the sample container 20 in the horizontal direction from the side of the sample container 20. The height direction of the sample container 20 is parallel to the vertical direction, and the camera optical axis of the third camera device 700 is perpendicular to the height direction of the sample container 20. In this way, it is convenient for the control device 500 to accurately obtain the total liquid level of the blood sample 30 and the height of the lower layer liquid 33 according to the image captured by the third camera device 700.

As an embodiment, the third camera device 700 performs the third shooting action on the sample container 20, including: the third camera device 700 directly shoots the image of the sample container 20 from the side of the sample container 20 or indirectly shoots the image of the sample container 20 through the second reflector 103. That is, the third camera device 700 is used to directly or indirectly shoot the image of the sample container 20 and/or the blood sample 30 in the sample container 20.

As an embodiment, the camera device further includes a second reflector 103, and the second reflector 103 is used to: when the third camera device 700 performs the third shooting action, reflect at least an image showing the whole picture of the sample container 20 in a two-dimensional form and/or a three-dimensional form to the third camera device 700. The third camera device 700 performs the third shooting action on the sample container 20, including: the third camera device 700 indirectly shoots the image of the sample container 20 through the second reflector 103. Of course, in a specific application, the sample analysis system 10 may also not be provided with the second reflector 103. For example, as an alternative embodiment, the third camera device 700 performs the third shooting action on the sample container 20, including: the third camera device 700 directly shoots the image of the sample container 20 from the side of the sample container 20.

As an implementation manner, the third camera device 700 is a third camera, and the sample analysis system 10 further includes a third fill light component 102. The third fill light component 102 is used to emit light toward the sample container 20 in the third shooting action to illuminate the sample container 20. Specifically, the third camera captures the full view of the blood sample 30 from the side of the sample container 20. The third fill light component 102 is mainly used to fill light for the full view of the blood sample 30 in the field of view of the third camera, so as to at least illuminate all the blood samples 30 in the sample container 20.

As an embodiment, the control device 500 is further configured to: when a third sample container 20 loaded with a blood sample 30 and having a total liquid volume less than a first threshold value, or a hematocrit of the blood sample 30 greater than a second threshold value, or a hematocrit of the blood sample 30 less than a third threshold value, or a hemolytic index of the blood sample 30 greater than a fourth threshold value, or a icteric index of the blood sample 30 greater than a fifth threshold value, or a lipemia index of the blood sample 30 greater than a sixth threshold value is placed in the sample storage device 100, control the sample container transfer device 300 to transfer the third sample container 20 loaded with the blood sample 30 and having been centrifugally stratified into an upper layer of liquid 31, a middle layer of liquid 32, and a lower layer of liquid 33 to the second shooting position; control the third camera device 700 to perform a third shooting action on the third sample container 20 located at the second shooting position; and control the sample container transfer device 300 to transfer the third sample container 20 after the third shooting action is completed and the upper layer of liquid 31 loaded therein has not been measured by the measuring mechanism 230 to the second storage space. The total liquid volume of the blood sample 30 is less than the first threshold value, indicating that the blood sample 30 has an abnormal liquid volume phenomenon. The hematocrit of the blood sample 30 is greater than the second threshold value or less than the third threshold value, indicating that the blood sample 30 has an abnormal hematocrit phenomenon. The hemolysis index of the blood sample 30 is greater than the fourth threshold value, or the icteric index of the blood sample 30 is greater than the fifth threshold value, or the lipemia index of the blood sample 30 is greater than the sixth threshold value, indicating that the blood sample 30 has an abnormal HIL phenomenon. The second storage space is used to recover sample containers 20 with abnormal liquid volume, abnormal hematocrit, and abnormal HIL. Since the total liquid volume of the blood sample 30 is too small, the hematocrit of the blood sample 30 is too large, the hematocrit of the blood sample 30 is too small, the hemolysis index of the blood sample 30 exceeds the standard, the icterus index of the blood sample 30 exceeds the standard, and the lipemia index of the blood sample 30 exceeds the standard, all of these may cause errors in the coagulation test result of the blood sample 30. Therefore, the present embodiment judges whether the total liquid volume of the blood sample 30 is abnormal, whether the hematocrit of the blood sample 30 is abnormal, whether the hemolysis index of the blood sample 30 is abnormal, whether the icterus index of the blood sample 30 is abnormal, and whether the lipemia index of the blood sample 30 is abnormal by taking a full-view image of the blood sample 30. When a blood sample 30 with abnormal liquid volume, abnormal hematocrit, or abnormal HIL enters the sample analysis system 10, the control device 500 controls the sample container transmission The transport device 300 transfers the blood sample 30 after the third camera device 700 completes the third shooting action and has not been measured by the measuring mechanism 230 to the second storage space, that is, the blood sample 30 with abnormal liquid volume, abnormal hematocrit or abnormal HIL phenomenon will not be sent to the measuring mechanism 230, thereby effectively preventing the measuring mechanism 230 from measuring the blood sample 30 with abnormal liquid volume, abnormal hematocrit or abnormal HIL phenomenon, that is, the blood sample 30 with abnormal liquid volume, abnormal hematocrit or abnormal HIL phenomenon is intercepted, at least saving the time for the measuring mechanism 230 to measure the blood sample 30 with abnormal liquid volume, abnormal hematocrit or abnormal HIL phenomenon, thereby helping to improve the sample measurement efficiency of the sample analysis system 10.

As an embodiment, the control device 500 controls the sample container transfer device 300 to transfer the third sample container 20 loaded with the blood sample 30 and having abnormal liquid volume, abnormal hematocrit or abnormal HIL phenomenon in the blood sample 30 to a node of the second storage space, which is located after the control device 500 determines that the blood sample 30 loaded in the third sample container 20 has abnormal liquid volume, abnormal hematocrit or abnormal HIL phenomenon according to the third target image.

As an implementation method, the second storage space and the first storage space are the same storage space, that is, the second storage space and the first storage space are located in the same area. The blood sample 30 with abnormal liquid volume, the blood sample 30 with abnormal hematocrit, the blood sample 30 with abnormal HIL, and the blood sample 30 with abnormal clot are recycled and processed in the same storage space. Of course, in a specific application, as an alternative implementation method, the second storage space and the first storage space can also be two different storage spaces.

As an embodiment, the above-mentioned obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the third target image includes: obtaining the total liquid level of the blood sample 30 in the sample container 20 according to the third target image, and obtaining the total liquid level of the sample container 20 according to the total liquid level. The total liquid volume of the blood sample 30 in the device 20. The total liquid volume of the blood sample 30 is the liquid volume detection result of the blood sample 30. In this embodiment, the liquid volume detection method of the blood sample 30 is: firstly obtain the total liquid level of the blood sample 30 through the full picture image of the blood sample 30, and then obtain the total liquid volume of the blood sample 30 according to the total liquid level of the blood sample 30. The operation method is simple.

As an embodiment, the above-mentioned obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the third target image includes: obtaining the total liquid level of the blood sample 30 in the sample container 20 and the height of the lower layer liquid 33 according to the third target image, and obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level and the height of the lower layer liquid 33. In this embodiment, the hematocrit detection method of the blood sample 30 is: firstly obtaining the total liquid level of the blood sample 30 and the height of the lower layer liquid 33 through the full image of the blood sample 30, and then obtaining the hematocrit of the blood sample 30 according to the total liquid level and the height of the lower layer liquid 33.

As an implementation method of obtaining the total liquid volume and the hematocrit according to the total liquid level and the height of the lower layer liquid 33, the above-mentioned obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the total liquid level includes: obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the total liquid level and a conversion function pre-stored in the sample analysis system 10, wherein the conversion function is a conversion relationship between the liquid level in the sample container 20 and the volume of the blood sample 30. The above-mentioned obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level and the height of the lower layer liquid 33 includes: obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level, the height of the lower layer liquid 33 and the conversion function. Specifically, the liquid volume and hematocrit are detected as follows: first, the total liquid level of the blood sample 30 and the height of the lower layer liquid 33 are obtained based on the full image of the blood sample 30, then the total volume (i.e., total liquid volume) of the blood sample 30 is converted based on the total liquid level and the conversion function of the pre-stored sample analysis system 10, then the volume of the lower layer liquid 33 is converted based on the height of the lower layer liquid 33 and the conversion function, and then the hematocrit of the blood sample 30 is obtained based on the total volume of the blood sample 30 and the volume of the lower layer liquid 33, thereby completing the detection of the liquid volume and hematocrit of the blood sample 30. The method of obtaining the total liquid volume and hematocrit of the blood sample 30 in this embodiment is suitable for the case where the sample analysis system 10 uses only one type of sample container 20.

In specific applications, there are many types of sample containers 20. The shape and size parameters of different types of sample containers 20 will be different. The difference in shape and size of the sample container 20 will affect the accuracy of the conversion result from height to volume, thereby affecting the accuracy of the liquid volume detection result and the hematocrit detection result of the blood sample 30. Among them, the influence of the shape and size of the sample container 20 on the calculation accuracy of the liquid volume in the sample container 20 is mainly reflected in the following points: 1) The inner diameter of the sample container 20 is different, that is, the inner diameters of different sample containers 20 are different, and it is difficult to achieve a unified inner diameter. 2) There is a draft angle when the sample container 20 is manufactured, resulting in inconsistency between the inner diameter of the tube mouth and the tube bottom of the sample container 20; 3) The shape of the bottom of the sample container 20 is a non-standard hemisphere, and it is difficult to model and calculate the volume of the bottom of the sample container 20. It can be seen that due to the irregular shape of the sample container 20, before performing liquid volume detection and hematocrit detection, it is necessary to obtain in advance the conversion relationship between the liquid level height in the sample container 20 of this type and the volume of the blood sample 30 to ensure the accuracy of the conversion result from height to volume.

In the above scheme, in the process of converting the volume according to the height, the conversion function used is pre-stored in the sample analysis system 10, that is, the conversion function is pre-stored in the sample analysis system 10 before the first blood sample 30 is measured after the sample analysis system 10 is installed, and the user end (the actual occasion for the measurement of the blood sample 30, such as the testing room of the hospital) does not need to execute any process to obtain the conversion function. Of course, in a specific application, as an alternative implementation, the conversion function can also be obtained according to the conversion function calibration process, that is, in this alternative implementation, according to the total liquid level, the total liquid volume of the blood sample 30 in the sample container 20 is obtained, including: according to the total liquid level and the conversion function obtained according to the conversion function calibration process, the total liquid volume of the blood sample 30 in the sample container 20 is obtained. The above-mentioned hematocrit of the blood sample 30 in the sample container 20 is obtained according to the total liquid level and the height of the lower layer liquid 33, including: according to the total liquid level, the height of the lower layer liquid 33 and the conversion function obtained according to the conversion function calibration process, the hematocrit of the blood sample 30 in the sample container 20 is obtained. In this alternative embodiment, after the sample analysis system 10 is installed, a conversion function is pre-stored in the sample analysis system 10 . During use at the user end, an updated conversion function is obtained by further executing a conversion function calibration process at the user end.

As another embodiment of obtaining the total liquid volume and the hematocrit according to the total liquid level and the height of the lower liquid 33, the above-mentioned obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the total liquid level includes: obtaining a conversion function pre-stored in the sample analysis system 10 and corresponding to the type of the sample container 20 according to the type of the sample container 20, and obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the total liquid level and the conversion function, wherein the conversion function is a conversion relationship between the liquid level in the sample container 20 and the volume of the blood sample 30. Obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level and the height of the lower liquid 33 includes: obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level, the height of the lower liquid 33 and the conversion function. The method of obtaining the liquid volume detection result and the hematocrit detection result in this embodiment is applicable to the case where the sample analysis system 10 uses at least two types of sample containers 20. In the related art prior to the present application, it is difficult to measure the inner diameters of all sample containers 20, which makes it difficult to accurately calculate the liquid volume and hematocrit of the blood sample 30 in each different type of sample container 20 according to the liquid level. In this embodiment, the conversion functions corresponding to the different types of sample containers 20 are pre-stored in the sample analysis system 10 in advance. In this way, in a specific application, only the type information of the sample container 20 and the liquid level of the blood sample 30 in the sample container 20 need to be obtained, and the total liquid volume and hematocrit of the blood sample 30 can be converted according to the conversion function. Among them, the type of the sample container 20 can be obtained by a barcode reader or visual shooting, or by loading different types of sample containers 20 separately in different loading areas.

In the above embodiment, in the process of converting the height to obtain the volume, the conversion function used is pre-stored in the sample analysis system 10. Of course, in a specific application, as an alternative implementation, the conversion function can also be obtained according to the conversion function calibration process, that is, in the alternative In the embodiment, the information used to characterize the liquid volume detection result of the blood sample 30 in the sample container 20 is obtained according to the total liquid level, including: obtaining a conversion function obtained according to the conversion function calibration process and corresponding to the type of the sample container 20 according to the type of the sample container 20, and obtaining the information used to characterize the liquid volume detection result of the blood sample 30 in the sample container 20 according to the total liquid level and the conversion function. The hematocrit of the blood sample 30 in the sample container 20 is obtained according to the total liquid level and the height of the lower layer liquid 33, including: obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level, the height of the lower layer liquid 33 and the conversion function obtained according to the conversion function calibration process and corresponding to the type of the sample container 20. In the alternative embodiment, after the sample analysis system 10 is installed, the conversion function will be pre-stored in the sample analysis system 10, and during the use of the user end, the updated conversion function will be further obtained by executing the conversion function calibration process at the user end.

As another embodiment of obtaining the total liquid volume and the hematocrit according to the total liquid level and the height of the lower layer liquid 33, the above-mentioned obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the total liquid level includes: obtaining the size parameters of the sample container 20 according to the instruction input by the operator through the human-computer interaction device; obtaining the total liquid volume of the blood sample 30 in the sample container 20 according to the total liquid level and the size parameters; the above-mentioned obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level and the height of the lower layer liquid 33 includes: obtaining the hematocrit of the blood sample 30 in the sample container 20 according to the total liquid level, the height of the lower layer liquid 33 and the size parameters. In this embodiment, the size parameters of the sample container 20 are obtained by manual input, and the control device 500 can obtain the liquid volume detection result and the hematocrit detection result of the blood sample 30 according to the liquid level obtained by shooting and the manually input size parameters of the sample container 20. It is not necessary to pre-store a conversion function between the liquid level in the sample container 20 and the volume of the blood sample 30 and to set a conversion function calibration process in the sample analysis system 10 .

As an embodiment, the sample container transmission device 300 includes a first conveying track 310, a first sample container scheduling mechanism 320 and a sample container transfer device 330. The first conveying track 310 is used to convey a sample seat having a single first container position, and the first container position is used to place a single sample container 20. The first sample scheduling mechanism is used to schedule the sample container 20 placed in the sample storage device 100 and loaded with a blood sample 30 to the sample seat located on the first conveying track 310. The sample container transfer device 330 is arranged between the first conveying track 310 and the sample measurement device 200, and is used to grab the sample containers 20 on the sample seat conveyed by the first conveying track 310 one by one to the sample rack inside the sample container transfer device 330, and then send the sample containers 20 to the sample measurement device 200 through the sample rack for measurement. The first conveying track 310 is the main conveying track of the sample analysis system 10, and the sample measurement device 200 is a sample processing device in the sample analysis system 10 for performing analysis functions on samples. The sample container transfer device 330 is also called an RBU module, which is mainly used to grab the sample containers 20 on the sample holder transported by the first transport track 310 one by one to the sample rack inside the sample container transfer device 330, and then send the sample containers 20 to the sample measurement device 200 through the sample rack for measurement. In this embodiment, the sample container transfer device 330 is set to achieve the effect of transferring the sample container 20 from the sample holder to the sample rack for transmission, so that the sample transmission function between the first transport track 310 component with the sample holder transmission function and the sample measurement device 200 with the sample rack transmission function can be realized without changing the structure of the first transport track 310 and the sample measurement device 200.

As an embodiment, the sample container transfer device 330 includes a sample seat scheduling mechanism, a second sample container scheduling mechanism and a sample rack scheduling mechanism. The sample seat scheduling mechanism is at least used to transfer the sample seat transferred to the sample container transfer device 330 by the first conveying track 310 to the rack position. The second sample container scheduling mechanism is used to schedule the sample container 20 on the sample seat at the rack position to the sample rack provided by the sample rack scheduling mechanism. The sample rack has at least two second container positions, each of which is used to place a single sample container 20. The sample rack scheduling mechanism is used to schedule the sample rack loaded with the sample container 20 and the blood sample 30 in the sample container 20 to the sample measurement device 200. The sample seat is a transmission carrier of a single sample container 20, and the sample rack is a transmission carrier of multiple sample containers 20. The sample seat scheduling mechanism is used to realize the connection between the sample container transfer device 330 and the first conveying track 310 on the one hand, and to realize the transmission of the sample seat in the sample container transfer device 330 on the other hand. The sample rack scheduling mechanism is used to realize the connection between the sample container transfer device 330 and the sample measurement device 200, and to realize the transfer of the sample rack in the sample container transfer device 330. The second sample container scheduling mechanism is used to realize the interaction between the sample seat scheduling mechanism and the sample rack scheduling mechanism, and to realize the transfer of the sample container 20 between the sample seat and the sample rack.

As an implementation, the first camera device 400 is used to perform a first shooting action on the sample container 20 transferred to the first shooting position by the sample container transfer device 330. In this implementation, the first camera device 400 is disposed in the sample container transfer device 330 to perform a first shooting action on the sample container 20 in the sample container transfer device 330. Of course, in specific applications, the setting position of the first camera device 400 is not limited thereto. For example, as an alternative embodiment, the first camera device 400 is disposed on the first conveying track 310, and the first camera device 400 is used to perform a first shooting action on the sample container 20 conveyed by the first conveying track 310 to the first shooting position; or, as another alternative embodiment, the first camera device 400 is disposed on the sample measuring device 200, and the first camera device 400 is used to perform a first shooting action on the sample container 20 conveyed by the sample measuring device 200 to the first shooting position; or, as yet another alternative embodiment, the first camera device 400 is disposed on the first sample container scheduling mechanism 320 or the sample storage device 100 or the first conveying track 310, and the first camera device 400 is used to perform a first shooting action on the sample container 20 dispatched by the first sample container scheduling mechanism 320 to the first shooting position.

As an embodiment, when the first camera device 400 is disposed in the sample container transfer device 330 , the first shooting position is located between the first conveying track 310 and the sample measuring device 200 along the path of the sample container transfer device 330 transferring the sample container 20 .

As an implementation, when the first camera device 400 is disposed on the first conveying track 310 , the first shooting position is located between the first sample scheduling mechanism and the sample container transfer device 330 along the path of the sample container 20 conveyed by the first conveying track 310 .

As an embodiment, when the first camera device 400 is provided in the sample measuring device 200, the first shooting position is located before the sample aspirating position of the sample measuring device 200 along the path of the sample measuring device 200 for conveying the sample container 20. A first sample aspirating conveying channel 210 for conveying the sample rack is provided in the sample measuring device 200, and the first shooting position, the sample aspirating position and the first sample aspirating conveying channel 210 are arranged at intervals.

As an embodiment, the sample seat scheduling mechanism includes a sample seat input channel, a sample seat transfer component, and a sample seat output channel. The sample seat input channel is used to transfer the sample seat delivered to the sample seat scheduling mechanism from the first conveying track 310 to the sample seat transfer component. The sample seat transfer component is at least used to transfer the sample seat from the sample seat input channel to the shelf position or the sample seat output channel. The sample seat output channel is used to transfer the sample seat delivered to the sample seat output channel via the sample seat transfer component to the first conveying track 310. The sample seat input channel is used to receive the sample seat delivered to the sample container transfer device 330 from the first conveying track 310. The sample seat transfer component is used to transfer the sample seat entering the sample container transfer device 330. The sample seat output channel is used to transfer the sample seat output from the sample container transfer device 330 to the first conveying track 310.

As an embodiment, the sample seat transfer assembly includes a turntable and a first power component, the turntable has a positioning portion for positioning the sample seat, and the first power component is used to drive the turntable to rotate so that the positioning portion rotates to at least a first import position, a shelf position and a first export position, respectively, wherein the first import position is a position for the sample seat transported by the sample seat input channel to enter the turntable, and the first export position is a position for guiding the sample seat transferred by the turntable to the sample seat output channel.

As an embodiment, the positioning portion is an open groove recessed from the outer edge of the turntable, the open groove is used to engage with the sample holder, and the open groove has an opening located at the outer edge of the turntable. The sample holder has a protrusion for inserting into the open groove and engaging with the open groove. The opening is the entrance for the sample holder to enter the turntable and the exit for the sample holder to detach from the turntable. In this embodiment, the open groove is used as the positioning portion, which is conducive to simplifying the structure of the turntable.

As an embodiment, the second sample container dispatching mechanism includes a second clamping part, a linear guide rail, a second power component and a third power component, wherein the second clamping part is used to clamp the sample container 20, the second power component is used to drive the second clamping part and the third power component to move linearly along the linear guide rail, and the third power component is used to drive the second clamping part to move up and down. The linear guide rail is used to guide the second clamping part to move horizontally and linearly, the second power component is used to provide a driving force for the second clamping part to move horizontally and linearly along the linear guide rail, and the third power component is used to provide a driving force for the second clamping part to move up and down in the vertical direction.

As an embodiment, the first rotation drive mechanism and the second sample container scheduling mechanism are the same mechanism, the first clamping portion and the second clamping portion are the same clamping portion, and the second sample container scheduling mechanism also includes the above-mentioned rotational power component for driving the first clamping portion to rotate. In this embodiment, the first camera device 400 is arranged in the sample container transfer device 330, and the second sample container scheduling mechanism is used as the first rotation drive mechanism, that is, the sample container transfer device 330 is reused to realize the function of the first rotation drive mechanism, so that there is no need to set up the first rotation drive mechanism separately, which is beneficial to simplify the structure of the sample analysis system 10 and reduce the cost of the sample analysis system 10. Of course, in a specific application, as an alternative embodiment, the first rotation drive mechanism and the second sample container scheduling mechanism can also be set as two independent mechanisms.

As an embodiment, the sample seat transfer component also includes a sample seat cache channel, the sample seat cache channel has an empty seat cache area, the empty seat cache area has a sample seat cache entrance and a sample seat cache exit, the empty seat cache area is used to cache empty sample seats, the sample seat cache entrance is used for empty sample seats from the turntable to enter the empty seat cache area, and the sample seat cache exit is used for empty sample seats from the empty seat cache area to the turntable. The turntable is used to regulate the conveying path of the sample seat on the sample seat cache channel, and the first power component is also used to drive the positioning part of the turntable to rotate to the second import position and the second export position respectively, the second import position is used for the empty sample seat conveyed from the sample seat cache exit to enter the turntable, and the second export position is used for the empty sample seat transferred by the turntable to the sample seat cache entrance. The empty seat cache area is used to cache a certain amount of empty sample seats to meet the loading requirements of transferring the sample container 20 from the sample rack to the sample seat after the sample suction is completed.

As an embodiment, the sample analysis system 10 further includes a centrifugal device 900, which is used to centrifuge the sample container 20 loaded with the blood sample 30 so that the blood sample 30 is centrifugally layered into an upper layer of liquid 31, an intermediate layer of liquid 32, and a lower layer of liquid 33. The sample storage device 100 is used to place the sample container 20 loaded with the blood sample 30 and not subjected to the centrifugal operation to achieve the loading of the uncentrifuged blood sample 30, and to place the sample container 20 loaded with the blood sample 30 and subjected to the centrifugal operation to achieve the loading of the centrifuged blood sample 30. The first sample container scheduling mechanism 320 is used to schedule the sample container 20 loaded with the blood sample 30 placed in the sample storage device 100 to the first conveying track 310, and the first conveying track 310 is used to convey the sample container 20 loaded with the uncentrifuged blood sample 30 to the centrifugal device 900 for centrifugation, and to convey the sample container 20 loaded with the centrifuged blood sample 30 to the sample container transfer device 330. In this embodiment, the sample analysis system 10 has a sample centrifugation function, which can meet the sample loading and measurement requirements of both uncentrifuged samples and centrifuged samples.

As an embodiment, the third camera device 700 is used to perform a third shooting action on the sample container 20 transported by the first conveying track 310 to the second shooting position, and the second shooting position is located on the first conveying track 310. The second shooting position is set on the path of the first conveying track 310 to transport the sample container 20 and is located between the first sample scheduling mechanism and the sample container transfer device 330. Of course, in a specific application, as an alternative embodiment, the third camera device 700 can also be set on the sample storage device 100 or the first sample container scheduling mechanism 320 or the sample container The transfer device 330 or the sample measurement device 200 .

As an implementation manner, the second photographing position is located between the centrifugal device 900 and the sample measuring device 200 .

As an implementation manner, the second shooting position is located between the centrifugal device 900 and the sample container transfer device 330 .

As an implementation manner, the second camera device is disposed in the sample container transport device 300 and is located beside the centrifugal device 900 .

As an embodiment, the sample analysis system 10 includes at least two sample measurement devices 200, and the at least two sample measurement devices 200 can be connected to the same sample container transfer device 330, or respectively connected to two independent sample container transfer devices 330. In this embodiment, the sample analysis system 10 can be a cascade system or a pipeline.

As an embodiment, the sample measuring device 200 includes a sample dispensing mechanism 220, a reagent dispensing mechanism 250, an incubation mechanism 240, and an optical measuring mechanism 230. The sample dispensing mechanism 220 is used to draw a blood sample 30 from the sample container 20, and to distribute at least a portion of the drawn blood sample 30 to a reaction container. The reagent dispensing mechanism 250 is used to draw a reagent from a reagent container, and to distribute at least a portion of the drawn reagent to a reaction container. The incubation mechanism 240 is used to incubate the blood sample 30 or a mixture of the sample and the reagent in the reaction container. The optical measuring mechanism 230 is used to measure a reaction solution made of the blood sample 30 and the reagent in the reaction container.

As an embodiment, the sample dispensing mechanism 220 includes a sample needle, a first suction and discharge driving component, and a first motion driving component; the sample needle is used to absorb and discharge the sample. The first suction and discharge driving component is used to provide driving force for the sample needle to absorb and discharge the sample. The first motion driving component is used to drive the sample needle to move in two-dimensional or three-dimensional space, so that the sample needle moves to different positions, such as the standby position, the sample suction position, the sample addition position, the cleaning position, etc.

As an embodiment, the first suction and discharge driving component is a syringe. Of course, in specific applications, the configuration of the first suction and discharge driving component is not limited thereto, and may also be a pump or a positive and negative pressure driving structure, for example.

As an embodiment, the sample measuring device 200 further includes a reaction container supply mechanism 270 and a reaction container transfer mechanism, wherein the reaction container supply mechanism 270 is used to provide a reaction container; and the reaction container transfer mechanism is used to transfer a reaction container. In the specific measuring process, the sample dispensing mechanism 220 distributes the blood sample 30 to the reaction container supplied by the reaction container supply mechanism 270, the reaction container transfer mechanism transfers the reaction container provided by the reaction container supply mechanism 270 and after the sample is added to the incubation mechanism 240, the reagent dispensing mechanism 250 distributes the reagent to the reaction container, the optical measuring mechanism 230 measures the reaction made by the blood sample 30 and the reagent in the reaction container, and the reaction container transfer mechanism discards and recycles the reaction container after the measurement is completed. In this embodiment, the reaction container is a disposable container, that is, the reaction container is discarded and recycled after carrying the blood sample 30 to complete the measurement of the corresponding measurement item, without the need to be cleaned and reused in the sample measuring device 200, thereby simplifying the structure and working procedures of the sample measuring device 200. Of course, in specific applications, the sample measuring device 200 can also use a recyclable reaction container.

As an embodiment, the sample measuring device 200 is a coagulation analyzer. The sample measuring device 200 also includes a reagent tray 260. The reagent dispensing mechanism 250 includes a mixed reagent dispensing component 251 and a trigger reagent dispensing component 252, wherein the mixed reagent dispensing component 251 is used to draw mixed reagent from the mixed reagent container on the reagent tray 260 and distribute it to the reaction container, and the trigger reagent dispensing component 252 is used to draw trigger reagent from the trigger reagent container on the reagent tray 260 and distribute it to the reaction container. Each coagulation test item includes at least a sample loading period, an incubation period, a trigger reagent period and a measurement period that are performed in sequence. Among them, during the sample loading period, the sample dispensing mechanism 220 draws blood sample 30 from the sample container 20 and distributes it to the reaction container to complete the sample loading operation. During the incubation period of the multi-reagent coagulation test item, the mixed reagent dispensing component 251 draws mixed reagent from the reagent container and distributes it to the reaction container, and the incubation mechanism 240 incubates the reaction container loaded with at least the blood sample 30 and the mixed reagent to complete the incubation operation of the multi-reagent coagulation test item. During the incubation period of the single-reagent coagulation assay, the incubation mechanism 240 incubates the reaction container loaded with at least the blood sample 30 to complete the incubation operation of the single-reagent coagulation assay. During the trigger reagent period, the trigger reagent dispensing component 252 draws the trigger reagent from the reagent container and distributes it to the reaction container, and mixes the reaction container to complete the trigger reagent addition operation. During the measurement period, the optical measurement mechanism 230 measures the reaction liquid in the reaction container to complete the measurement operation. Of course, in specific applications, the sample measurement device 200 is not limited to a coagulation analyzer. For example, as an alternative embodiment, the sample measurement device 200 can also be a biochemical analyzer, an immunoassay analyzer, etc.

As an embodiment, the processing process of the blood sample 30 used in the determination of coagulation items includes: using sodium citrate as an anticoagulant, mixing the anticoagulant and the blood sample 30 thoroughly, and then centrifuging on a centrifuge 900; due to the different densities of red blood cells, white blood cells, platelets and plasma, the blood sample 30 after centrifugation is divided into three layers, the bottom layer is mainly red blood cells; the top layer is plasma, which is light yellow; between the red blood cells and plasma is a white film layer, the main components of which are white blood cells and platelets; the determination of coagulation items mainly involves the absorption and analysis of the plasma above, and the plasma used for the determination of coagulation items is also called platelet-poor plasma.

As an embodiment, the control device 500 is further configured to: display the first target image, the determination result for characterizing whether the intermediate layer liquid 32 has a clot, and the determination result for characterizing the degree of coagulation of the blood sample 30 in the sample test report and/or transmit it to a laboratory information management system that is communicatively connected to the sample analysis system 10 according to the first target image. The laboratory information management system is also called the laboratory information system, i.e., the LIS (full name: Laboratory Information System) system. In this embodiment, displaying the first target image, the determination result for characterizing whether the intermediate layer liquid 32 has a clot, and the determination result for characterizing the degree of coagulation of the blood sample 30 in the sample test report and/or the laboratory information management system can facilitate medical personnel to conveniently and intuitively obtain information related to whether the blood sample 30 has premature coagulation.

As an embodiment, the sample analysis system 10 further includes a first display 101, which is independently provided with the sample measuring device 200, and is used to display at least the storage information of the blood sample 30 in the sample storage device 100 and the information of the blood sample 30 transmitted by the sample container transmission device 300. The control device 500 is further configured to display at least one of the following information on the display interface of the first display 101: a first target image, a result of determining whether the intermediate layer liquid 32 has a clot, and a result of determining the degree of coagulation of the blood sample 30. The first display 101 is a display at the operating end of the cascade system or the pipeline.

As an embodiment, the sample measuring device 200 includes a second display, which is used to display at least the measuring item information of the blood sample 30 in the sample measuring device 200. The control device 500 is further configured to display at least one of the following information on the display interface of the second display: a first target image, a result of determining whether the intermediate layer liquid 32 has a clot, and a result of determining the degree of coagulation of the blood sample 30. The second display is a display provided by the sample measuring device 200, that is, a display of the analyzer.

As an embodiment, the control device 500 is configured to: output the first target image according to the first target image. In this embodiment, the control device 500 does not directly output the determination result for characterizing whether the intermediate layer liquid 32 has a clot and/or the determination result for characterizing the degree of coagulation of the blood sample 30, but outputs the first target image for the operator and the medical staff to manually determine whether the intermediate layer liquid 32 has a clot and the degree of coagulation of the blood sample 30. Since the first target image at least includes an image showing the interface liquid surface 321 or the interface liquid layer in a two-dimensional form and/or a three-dimensional form, the medical staff can quickly determine whether the intermediate layer liquid 32 has a clot, the degree of coagulation of the blood sample 30, and whether there is an abnormal coagulation phenomenon in the blood sample 30 according to the image showing the interface liquid surface 321 or the interface liquid layer in a two-dimensional form and/or a three-dimensional form, without having to find the blood sample 30 for confirmation.

As an implementation manner, the control device 500 is configured to: display the first target image in the sample test report and/or transmit it to a laboratory information management system that is communicatively connected to the sample analysis system 10 .

As an implementation manner, the control device 500 is configured to: display the first target image on the display interface of the first display 101 .

As an implementation manner, the control device 500 is configured to: display the first target image on the display interface of the second display.

An implementation scheme of this embodiment mainly adopts an optical photography method to take a picture of the white film layer of the centrifuged blood sample 30 to determine whether the blood sample 30 has a premature coagulation problem, and upload the relevant image to display it to medical staff, or make a special mark on the result of the blood sample 30.

In a further preferred embodiment, the sample analysis system 10 mainly adopts an optical photography method to take photos of the whole image and the white film layer of the centrifuged blood sample 30, and uses the whole image information of the blood sample 30 to calculate the liquid volume detection result, HCT detection result and HIL detection result of the blood sample 30, and uses the method of taking photos of the white film layer to obtain the clot detection result of the blood sample 30. In this way, the clot of the blood sample 30 is pre-checked, and the blood sample 30 suspected of having abnormal clot phenomenon is intercepted and transported to a designated area (i.e., the first storage space) so that it does not enter the sample measurement device 200 (e.g., a coagulation analyzer) for measurement. In addition, in a further scheme, the total liquid volume, HIL, and HCT can also be pre-checked, and the blood sample 30 with abnormal total liquid volume, abnormal HIL, and abnormal HCT can be intercepted and transported to a designated area (i.e., the second storage space) so that it does not enter the sample measurement device 200 for measurement.

Embodiment 2:

1 to 7 , the sample analysis system 10 provided in this embodiment differs from that in the first embodiment mainly in that the first camera device 400 captures and obtains an image at least including the interface liquid surface 321 or the interface liquid layer displayed in a two-dimensional form and/or a three-dimensional form, which is specifically embodied in that: in the first embodiment, the first camera device 400 obtains an image at least including the interface liquid surface 321 or the interface liquid layer displayed in a two-dimensional form and/or a three-dimensional form by indirectly capturing the image in the reflector; whereas in the present embodiment, the first camera device 400 obtains an image at least including the interface liquid surface 321 or the interface liquid layer displayed in a two-dimensional form and/or a three-dimensional form by directly capturing the sample container 20.

Specifically, in this embodiment, the first camera device 400 performs the first shooting action on the sample container 20, including: the first camera device 400 directly shoots the image of the sample container 20 from the oblique upper side of the intermediate layer liquid 32 toward the sample container 20, so that the first camera device 400 can directly shoot the entire horizontal liquid surface of the intermediate layer liquid 32, that is, the entire interface liquid surface 321, so as to achieve the purpose of shooting and obtaining the first target image. In order to ensure the shooting focal length, the horizontal distance between the first camera device 400 and the sample container 20 when performing the first shooting action in this embodiment is greater than the horizontal distance between the first camera device 400 and the sample container 20 when performing the first shooting action in the first embodiment. Of course, in specific applications, the first camera device 400 directly shoots the entire horizontal liquid surface of the intermediate layer liquid 32 from other directions. For example, as an alternative embodiment, when the first camera device 400 performs the first shooting action, the first camera device 400 directly shoots the image of the sample container 20 from directly above or obliquely below the intermediate layer liquid 32 toward the sample container 20.

As an embodiment, the first camera device 400 performs a first shooting action on the sample container 20, including: the first camera device 400 is used to shoot an image of the sample container 20 from the upper oblique part of the intermediate layer of liquid 32 directly toward the sample container 20, with the camera optical axis and the horizontal direction forming a preset angle A, and the preset angle A is greater than or equal to 10° and less than or equal to 70°. In this embodiment, the preset angle A formed by the camera optical axis of the first camera device 400 and the horizontal direction is limited to be greater than or equal to 10° and less than or equal to 70°, so that the first camera device 400 can directly shoot the entire horizontal liquid surface of the intermediate layer of liquid 32.

As an implementation scheme, the preset angle A is greater than or equal to 20° and less than or equal to 50°.

Except for the above differences, other parts of the sample analysis system 10 provided in this embodiment can refer to the first embodiment and will not be described in detail here.

Embodiment three:

The sample analysis system 10 provided in the present embodiment differs from the first embodiment mainly in the different methods for determining the target shooting orientation, which is specifically embodied in the following aspects: in the first embodiment, during the relative horizontal rotation of the sample container 20 and the second camera device through a first preset stroke, multiple images are captured, and an image with the smallest obstruction area or no obstruction is found among the multiple images, and the shooting orientation corresponding to the image is determined as the target shooting orientation; whereas in the present embodiment, the first preset stroke is not set, and during the relative horizontal rotation of the sample container 20 and the second camera device, if a captured image shows that the obstruction area on the sample container 20 is less than or equal to a preset threshold or no obstruction on the sample container 20 is displayed, the shooting orientation corresponding to the image is determined as the target shooting orientation.

Specifically, in this embodiment, when the control device 500 obtains the target shooting orientation, it includes: controlling one of the sample container 20 and the second camera device to rotate relative to the other around the axis MN perpendicular to the horizontal direction; in the process of rotating one of the sample container 20 and the second camera device relative to the other around the axis MN perpendicular to the horizontal direction, controlling the second camera device to capture an image of the sample container 20 at a first preset time interval to perform a second shooting action; when an image captured by the second camera device shows that the area of the obstruction on the sample container 20 is less than or equal to a preset threshold or the obstruction on the sample container 20 is not displayed, the shooting orientation corresponding to the image showing that the area of the obstruction on the sample container 20 is less than or equal to the preset threshold or the obstruction on the sample container 20 is not displayed is determined as the target shooting orientation. In this embodiment, when executing the second shooting action, the relative rotation stroke of the sample container 20 and the second camera device is not preset. In the process of one of the sample container 20 and the second camera device rotating relative to the other around the axis MN perpendicular to the horizontal direction, images are captured at equal intervals until the captured image shows that the area of the obstruction on the sample container 20 is less than or equal to the preset threshold or the obstruction on the sample container 20 is not displayed, which means that it is determined that the target shooting direction has been found.

As an embodiment, the control device 500 is further configured to: when the area of the obstruction on the sample container 20 shown in an image captured by the second camera device is less than or equal to a preset threshold or the obstruction on the sample container 20 is not shown, control one of the sample container 20 and the second camera device to stop rotating relative to the other about the axis MN perpendicular to the horizontal direction. In this embodiment, when the target shooting orientation is found, control one of the sample container 20 and the second camera device to stop rotating relative to the other about the axis MN perpendicular to the horizontal direction.

Except for the above differences, other parts of the sample analysis system 10 provided in this embodiment can refer to the first and second embodiments and will not be described in detail here.

Embodiment 4:

The sample analysis system 10 provided in this embodiment is different from that in the first embodiment mainly in that the method of obtaining the first target image is different, which is specifically embodied in that: in the first embodiment, dynamic shooting is first performed (i.e., shooting is performed during the relative rotation of the sample container 20 and the second camera device) to find the target shooting orientation, and then static shooting is performed based on the target shooting orientation to obtain the first target image; while in the present embodiment, there is no need to find the target shooting orientation first, and dynamic shooting is performed directly and one of the images is used as the first target image.

Specifically, in this embodiment, the control device 500 obtains the first target image including: controlling one of the sample container 20 and the first camera device 400 to rotate relative to the other about an axis MN perpendicular to the horizontal direction, controlling the first camera device 400 to capture an image of the sample container 20 to perform a first capture action during the process of one of the sample container 20 and the first camera device 400 rotating relative to the other about the axis MN perpendicular to the horizontal direction, and using an image captured by the first camera device 400 during the process of one of the sample container 20 and the first camera device 400 rotating relative to the other about the axis MN perpendicular to the horizontal direction as the first target image. In this embodiment, the first target image is obtained by capturing multiple images by the first camera device 400 during the process of one of the sample container 20 and the first camera device 400 rotating relative to the other about the axis MN perpendicular to the horizontal direction, and using one of the multiple images as the first target image, that is, the first target image is obtained by dynamic capture without the need to find the target capture orientation separately.

As an embodiment, the control device 500 obtains the first target image including: controlling one of the sample container 20 and the first camera device 400 to rotate relative to the other about an axis MN perpendicular to the horizontal direction for a second preset stroke, and in the process of one of the sample container 20 and the first camera device 400 rotating relative to the other about an axis MN perpendicular to the horizontal direction for the second preset stroke, controlling the first camera device 400 to capture a second number of images of the sample container 20 to perform a first capturing action, and taking an image of the second number of images of the sample container 20 showing the smallest area of occlusions on the sample container 20 or showing no occlusions on the sample container 20 as the first target image. In this embodiment, in the process of the sample container 20 and the second camera device rotating relative to each other horizontally for the second preset stroke, multiple images are captured, and an image of the smallest area of occlusions or no occlusions is found among the multiple images, and the image is taken as the first target image.

As an embodiment, the second preset stroke is equal to 360°. During the process of the sample container 20 and one of the second camera devices rotating one circle around the vertically arranged axis MN, multiple images are taken, and an image with the smallest obstruction area or no obstruction is found among the multiple images, and this image is used as the first target image.

In the above solution, during the process of rotating one of the sample container 20 and the first camera device 400 about the vertically arranged axis MN for the second preset stroke, multiple images are captured, and an image with the smallest area of the obstruction or no obstruction is found among the multiple images, and the image is recorded as The image is taken as the first target image. Of course, in specific applications, in this embodiment, the first preset stroke is not set. During the relative horizontal rotation of the sample container 20 and the second camera device, if a captured image shows that the area of the obstruction on the sample container 20 is less than or equal to the preset threshold or the obstruction on the sample container 20 is not displayed, the shooting orientation corresponding to the image is determined as the target shooting orientation. Of course, in specific applications, the method of dynamically taking multiple images and taking one of the images as the first target image is not limited to the above scheme. For example, as an alternative implementation scheme, the second preset stroke may not be set. During the relative horizontal rotation of the sample container 20 and the first camera device 400, images are taken at equal intervals until the captured image shows that the area of the obstruction on the sample container 20 is less than or equal to the preset threshold or the obstruction on the sample container 20 is not displayed, and the image is taken as the first target image. Specifically, in this alternative embodiment, the control device 500 obtains the first target image including: controlling one of the sample container 20 and the first camera device 400 to rotate relative to the other around an axis MN perpendicular to the horizontal direction; during the process of rotating one of the sample container 20 and the first camera device 400 relative to the other around the axis MN perpendicular to the horizontal direction, controlling the first camera device 400 to capture an image of the sample container 20 at a second preset time interval to perform a first shooting action; when an image captured by the first camera device 400 shows that the area of the obstruction on the sample container 20 is less than or equal to the preset threshold or the area of the obstruction on the sample container 20 is not displayed, an image in which the area of the obstruction on the sample container 20 is less than or equal to the preset threshold or the area of the obstruction on the sample container 20 is displayed as the first target image.

In addition to the above differences, other parts of the sample analysis system 10 provided in this embodiment can refer to the first to third embodiments and will not be described in detail here.

Embodiment five:

The sample analysis system 10 provided in this embodiment is different from that in the first embodiment mainly in whether the first camera device 400 for photographing an image showing the interface liquid surface 321 or the interface liquid layer in a two-dimensional form and/or a three-dimensional form and the third camera device 700 for photographing the height position of the interface liquid surface 321 or the interface liquid layer are the same camera device, which is specifically reflected in: in the first embodiment, the first camera device 400 and the third camera device 700 are two different camera devices; while in this embodiment, the first camera device 400 and the third camera device 700 are the same camera device.

Specifically, in this embodiment, the third camera device 700 and the first camera device 400 are the same camera device, that is, the first camera device 400 is reused to perform the third shooting action and the first shooting action.

As an embodiment, the first camera device 400 includes an adjustment component, which is at least used to adjust the shooting angle of the first camera device 400. The control device 500 is further configured to: first control the first camera device 400 to perform the third shooting action on the sample container 20 in the horizontal direction, then control the adjustment component to adjust the shooting angle of the first camera device 400, and then control the first camera device 400 after adjusting the shooting angle to perform the first shooting action on the sample container 20 from the oblique upper side of the intermediate layer liquid 32. In this embodiment, by setting the adjustment component, the same camera device can meet the requirements of different shooting angles of the third shooting action and the first shooting action.

As an embodiment, after controlling the first camera device 400 to perform the third shooting action on the sample container 20 in the horizontal direction, and before controlling the first camera device 400 after adjusting the shooting angle to perform the first shooting action on the sample container 20 from obliquely above the intermediate layer liquid 32, in addition to controlling the adjustment component to adjust the shooting angle of the first camera device 400, it is also necessary to control and adjust the height position of the sample container 20 and/or the first camera device 400.

Except for the above differences, other parts of the sample analysis system 10 provided in this embodiment can refer to the first to fourth embodiments and will not be described in detail here.

Embodiment six:

1 to 6 and 8 , the sample analysis system 10 provided in this embodiment differs from that in the first embodiment mainly in that the sample container transmission device 300 is set differently, specifically, in the first embodiment, the sample container transmission device 300 can realize the conversion from transmitting the sample container 20 on the sample seat to transmitting the sample container 20 on the sample rack, and the sample container transmission device 300 can transmit two types of carriers of the sample containers 20; whereas in this embodiment, the sample container transmission device 300 is used to transmit a single carrier of the sample container 20.

Specifically, in this embodiment, the sample container transmission device 300 includes a second conveying track 340 and a third sample container scheduling mechanism 350. The third sample container scheduling mechanism 350 is used to schedule the sample container 20 placed in the sample storage device 100 and loaded with the blood sample 30 to the second conveying track 340. The second conveying track 340 is used to transport the sample container 20 to the sample measurement device 200. The second conveying track 340 transmits the sample container 20 through the sample seat or sample rack, that is, the second conveying track 340 is used to transport the sample seat or sample rack.

As an embodiment, the first camera device 400 is used to perform a first shooting action on the sample container 20 transported to the first shooting position by the second conveying track 340. In this embodiment, the first camera device 400 is arranged on the second conveying track 340 to perform a first shooting action on the sample container 20 transported by the second conveying track 340. Of course, in specific applications, the setting position of the first camera device 400 is not limited thereto. For example, as an alternative embodiment, the first camera device 400 is arranged on the third sample container scheduling mechanism 350 or the sample storage device 100 or the second conveying track 340, and the first camera device 400 is used to perform a first shooting action on the sample container 20 dispatched to the first shooting position by the third sample container scheduling mechanism 350; or, as another alternative embodiment, the first camera device 400 is arranged on the sample measuring device 200, and the first camera device 400 is used to perform a first shooting action on the sample container 20 transported to the first shooting position by the sample measuring device 200.

As an implementation manner, when the first camera device 400 is located on the second conveying track 340 , the fourth shooting position is located between the third sample container scheduling mechanism 350 and the sample measuring device 200 along the conveying path of the second conveying track 340 .

As an implementation manner, when the first camera device 400 is located at the third sample container scheduling mechanism 350 , the first shooting position is located between the sample storage device 100 and the second conveying track 340 along the scheduling path of the third sample container scheduling mechanism 350 .

As an implementation, when the first camera device 400 is located in the sample measuring device 200 , the first photographing position is located before the sample aspirating position of the sample measuring device 200 along the path of the sample measuring device 200 for conveying the sample container 20 .

In addition to the above differences, other parts of the sample analysis system 10 provided in this embodiment can refer to the first to fifth embodiments and will not be described in detail here.

Embodiment seven:

1 to 6 and 9 , the sample analysis system 10 provided in this embodiment differs from that in the first embodiment mainly in the arrangement of the sample container transmission device 300 and the preferred arrangement position of the first camera device 400, which is specifically embodied in that: in the first embodiment, the sample container transmission device 300 can realize the conversion from transmitting the sample container 20 on the sample seat to transmitting the sample container 20 on the sample rack, and the first camera device 400 is preferably arranged on the sample container transfer device 330; whereas in the present embodiment, the sample container transmission device 300 is used to transmit a single carrier of the sample container 20, and the first camera device 400 is preferably arranged on the conveying track and located behind the centrifuge 900.

Specifically, in this embodiment, the sample analysis system 10 further includes a centrifugal device 900, which is used to centrifuge the sample container 20 loaded with the blood sample 30 so that the blood sample 30 is centrifugally layered into an upper layer of liquid 31, a middle layer of liquid 32, and a lower layer of liquid 33. The sample storage device 100 is used to allow the sample container 20 loaded with the blood sample 30 and not subjected to the centrifugal operation to be placed therein so as to load the uncentrifuged blood sample 30, and to allow the sample container 20 loaded with the blood sample 30 and subjected to the centrifugal operation to be placed therein so as to load the centrifuged blood sample 30. The sample container transfer device 300 includes a third conveying track 360 and a fourth sample container scheduling mechanism 370. The fourth sample container scheduling mechanism 370 is used to schedule the sample container 20 placed in the sample storage device 100 and loaded with a blood sample 30 to the third conveying track 360. The third conveying track 360 is used to convey the sample container 20 loaded with uncentrifuged blood samples 30 to the centrifuge device 900 for centrifugation and to convey the sample container 20 loaded with centrifuged blood samples 30 to the sample measuring device 200.

As an embodiment, the first camera device 400 is used to perform a first photographing action on the sample container 20 transported to the first photographing position by the third transport track 360, and the first photographing position is located between the centrifugal device 900 and the sample measuring device 200 along the transport path of the third transport track 360. In this embodiment, the first camera device 400 is arranged on the third transport track 360 and is located between the centrifugal device 900 and the sample measuring device 200, so as to perform a first photographing action on the centrifuged sample container 20 transported by the second transport track 340. Of course, in specific applications, the setting position of the first camera device 400 is not limited to this. For example, as an alternative embodiment, the first camera device 400 is arranged on the sample measuring device 200, and the first camera device 400 is used to perform a first photographing action on the sample container 20 transported to the first photographing position by the sample measuring device 200, and the first photographing position is located before the sample suction position of the sample measuring device 200 along the path of the sample measuring device 200 transporting the sample container 20.

In addition to the above differences, other parts of the sample analysis system 10 provided in this embodiment can refer to the first to fifth embodiments and will not be described in detail here.

Embodiment eight:

1 to 6 and 10 , the sample analysis system 10 provided in this embodiment differs from that in the first embodiment mainly in the form of the sample analysis system 10 , which is specifically embodied in that: in the first embodiment, the sample analysis system 10 is a cascade system or assembly line including at least two sample measuring devices 200 ; whereas in this embodiment, the sample analysis system 10 is a single analyzer including a single sample measuring device 200 .

Specifically, in this embodiment, the sample container transmission device 300 includes a sample suction delivery channel 210 and a fifth sample container scheduling mechanism 380. The sample storage device 100 is used to place the sample container 20 loaded with the blood sample 30 and after the centrifugal operation to realize the loading of the blood sample 30 after the centrifugation. The fifth sample scheduling mechanism is used to schedule the sample container 20 placed in the sample storage device 100 and loaded with the blood sample 30 to the sample suction delivery channel 210. The sample measurement device 200 is used to absorb at least part of the upper liquid 31 from the sample container 20 in the sample suction delivery channel 210 and distribute it to the reaction container for reaction and measurement.

As an embodiment, the first camera device 400 is used to perform a first shooting action on the sample container 20 that is dispatched to the first shooting position by the fifth sample container scheduling mechanism 380, and the first shooting position is located between the sample storage device 100 and the sample suction and delivery channel 210 along the scheduling path of the fifth sample scheduling mechanism; or, the first camera device 400 is used to perform a first shooting action on the sample container 20 that is transported to the first shooting position by the sample suction and delivery channel 210, and the first shooting position is located before the sample suction position of the sample measuring device 200 along the path of transporting the sample container 20 by the sample suction and delivery channel 210.

In addition to the above differences, other parts of the sample analysis system 10 provided in this embodiment can refer to the first to fifth embodiments and will not be described in detail here.

Embodiment nine:

The sample analysis system 10 provided in this embodiment is different from the first embodiment mainly in that the information outputted according to the first target image is different, which is specifically reflected in: in the first embodiment, the first target image is outputted for the operator and the medical staff to manually judge whether the intermediate layer liquid 32 has coagulation. and the degree of coagulation of the blood sample 30; and in this embodiment, the control device 500 can directly output a determination result of whether the intermediate layer liquid 32 has a clot and/or a determination result of the degree of coagulation of the blood sample 30 according to the first target image.

Specifically, in this embodiment, the control device 500 is configured to: output at least a determination result for characterizing whether the intermediate layer liquid 32 has a clot and/or a determination result for characterizing the degree of coagulation of the blood sample 30 according to the first target image. In this embodiment, the control device 500 can directly output a determination result for characterizing whether the intermediate layer liquid 32 has a clot and/or a determination result for characterizing the degree of coagulation of the blood sample 30. Of course, in a specific application, the control device 500 can also output the first target image at the same time when outputting a determination result for characterizing whether the intermediate layer liquid 32 has a clot and/or a determination result for characterizing the degree of coagulation of the blood sample 30.

As an embodiment, the control device 500 is configured to: display the determination result for characterizing whether the intermediate layer liquid 32 has a clot and/or the determination result for characterizing the degree of coagulation of the blood sample 30 in a sample test report and/or transmit it to a laboratory information management system that is communicatively connected to the sample analysis system 10.

As an embodiment, the control device 500 is configured to display, on the display interface of the second display, a determination result indicating whether the intermediate layer liquid 32 has clots and/or a determination result indicating the degree of coagulation of the blood sample 30 .

As an embodiment, the control device 500 is configured to display, on the display interface of the first display 101 , a determination result indicating whether the intermediate layer liquid 32 has clots and/or a determination result indicating the degree of coagulation of the blood sample 30 .

As an embodiment, the control device 500 is further configured to: according to the first target image, for the blood sample 30 with clots in the middle liquid layer, use a mark to display it in the sample test report and/or transmit it to the laboratory information management system. The marking method may be to add "*" or other marks before the result of the sample test report, or to use different color marks, or to use text prompt marks to distinguish normal blood samples 30 from blood samples 30 with premature coagulation, so as to facilitate the operator to distinguish them.

As an embodiment, the control device 500 is further configured to: determine the coagulation degree of the blood sample 30 according to the first target image, and respectively use at least two different identification methods for at least two blood samples 30 with different coagulation degrees, and display them in the sample test report and/or transmit them to the laboratory information management system. In this embodiment, according to the different degrees of premature coagulation, a hierarchical display scheme is adopted, that is, different identification methods are used to distinguish blood samples 30 with different degrees of premature coagulation, so that medical personnel can more intuitively obtain information on the degree of premature coagulation.

As an embodiment, the control device 500 is further configured to: obtain a determination result for characterizing whether the intermediate layer liquid 32 has a clot according to at least one of the following features: whether there is a feature for characterizing a depression in the image of the interface liquid surface 321 or the interface liquid layer, whether there is a feature for characterizing a protrusion in the image of the interface liquid surface 321 or the interface liquid layer, and a feature for characterizing surface flatness in the image of the interface liquid surface 321 or the interface liquid layer. In this embodiment, it is determined whether the intermediate layer liquid 32 has a clot according to whether there is a feature for characterizing a depression and a feature for characterizing a protrusion in the image of the interface liquid surface 321 or the interface liquid layer. Of course, in a specific application, in an alternative embodiment, the control device 500 can also be configured to: obtain a determination result for characterizing whether the intermediate layer liquid 32 has a clot according to the feature for characterizing surface flatness in the image of the interface liquid surface 321 or the interface liquid layer.

As an embodiment, the control device 500 is further configured to: obtain a determination result for characterizing the degree of coagulation of the blood sample 30 according to at least one of the following features: the number of features characterizing depressions in the image of the interface liquid surface 321 or the interface liquid layer, the number of features characterizing protrusions in the image of the interface liquid surface 321 or the interface liquid layer, and the size of features characterizing depressions in the image of the interface liquid surface 321 or the interface liquid layer. The size of features characterizing depressions includes the size for characterizing the degree of depression, i.e., the depth, width, and length of the depression. The size of features characterizing protrusions includes the size for characterizing the degree of protrusion, i.e., the height, width, and length of the protrusion.

As an embodiment, the control device 500 is further configured to: train the artificial intelligence model according to the first target images of the plurality of blood samples 30, so that the model can better accurately output the determination result for characterizing whether the intermediate layer liquid 32 has a clot and/or the determination result for characterizing the degree of coagulation of the blood sample 30 according to the first target image, so that the model can make predictions or decisions on the unknown first target image. Of course, in a specific application, as an alternative embodiment, the control device 500 can also be configured to: output the determination result for characterizing whether the intermediate layer liquid 32 has a clot and/or the determination result for characterizing the degree of coagulation of the blood sample 30 according to the first target image and a preset image processing program.

In addition to the above differences, other parts of the sample analysis system 10 provided in this embodiment can refer to the first to eighth embodiments and will not be described in detail here.

Embodiment ten:

The sample analysis system 10 provided in this embodiment is different from that in the ninth embodiment mainly in that the method of judging whether the blood sample 30 has a clot and/or determining the degree of coagulation of the blood sample 30 is different, which is specifically reflected in that: in the ninth embodiment, whether the blood sample 30 has a clot and/or determining the degree of coagulation of the blood sample 30 is judged solely based on the first target image containing the intermediate layer liquid 32; while in this embodiment, whether the blood sample 30 has a clot and/or determining the degree of coagulation of the blood sample 30 is comprehensively judged in combination with the first target image containing the intermediate layer liquid 32, the second target image containing the upper layer liquid 31, and the needle blockage judgment result.

Specifically, in this embodiment, the sample analysis system 10 further includes a fourth camera device, which is used to capture the blood sample 30 loaded with the sample container 20 and the blood sample 30 is centrifuged and stratified into the upper liquid layer before the sample measuring device 200 draws the upper liquid 31 from the sample container 20. The sample container 20 after the first camera device 400 performs the first shooting action, the middle layer liquid 32, and the lower layer liquid 33 performs the fourth shooting action; the sample measuring device 200 includes a sample dispensing mechanism 220, a reagent dispensing mechanism 250, and an optical measuring mechanism 230; the sample dispensing mechanism 220 includes a sample needle and a needle blocking detection component, the sample needle is used to suck at least part of the upper layer liquid 31 from the sample container 20 after the first camera device 400 performs the first shooting action and the fourth camera device performs the fourth shooting action and distribute it to the reaction container, the needle blocking detection component is used to detect the parameters used to characterize whether the sample needle is blocked during the sample aspiration process; the reagent dispensing mechanism 250 is used to suck at least part of the upper layer liquid 31 from the sample container 20 after the fourth camera device performs the fourth shooting action and distribute it to the reaction container. At least part of the reagent is drawn from the reagent container and distributed into the reaction container; the optical measurement mechanism 230 is used to optically measure the reaction liquid made of at least the blood sample 30 and the reagent in the reaction container; the control device 500 is further configured to: obtain a second target image including an image of the upper layer liquid 31 according to the image captured by the fourth camera device performing the fourth shooting action; determine whether the sample needle is blocked according to the feedback information of the needle blocking detection component; determine whether the blood sample 30 has a clot and/or determine the degree of coagulation of the blood sample 30 according to at least two of the first target image, the second target image and the determination result of whether the sample needle is blocked. In this embodiment, the first target image including the intermediate layer liquid 32, the second target image including the upper layer liquid 31 and the determination result of whether the sample needle is blocked are combined to comprehensively determine whether the blood sample 30 has a clot and/or determine the degree of coagulation of the blood sample 30, which is conducive to improving the accuracy of the determination result.

As an implementation manner, the fourth camera device and the first camera device 400 are the same camera device, or the fourth camera device and the first camera device 400 are two independent camera devices.

In addition to the above differences, other parts of the sample analysis system 10 provided in this embodiment can refer to the first to ninth embodiments and will not be described in detail here.

Embodiment eleven:

The sample analysis system 10 provided in this embodiment is different from that in the first embodiment mainly in that the emphasis of protection is different, which is specifically reflected in that: in the first embodiment, the emphasis is on protection, and the first camera device 400 performs a first shooting action to obtain an image that at least displays the interface liquid surface 321 or the interface liquid layer in a two-dimensional form and/or a three-dimensional form; while in the present embodiment, the emphasis is on protection, and the first camera device 400 performs a first shooting action on the sample container 20 from obliquely above or obliquely below the intermediate layer liquid 32 to obtain an image that at least includes the intermediate layer liquid 32.

Specifically, the sample analysis system 10 provided in this embodiment includes a sample storage device 100, a sample measuring device 200, a sample container transmission device 300, a first camera device 400 and a control device 500. The sample storage device 100 is at least used for placing a sample container 20 loaded with a blood sample 30 to achieve the loading of the blood sample 30. The sample measuring device 200 is used to absorb at least part of the upper layer liquid 31 from the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and separated into an upper layer liquid 31, an intermediate layer liquid 32 and a lower layer liquid 33, and distribute it to a reaction container for reaction and measurement, and the intermediate layer liquid 32 at least contains platelets and/or leukocytes. The sample container transmission device 300 is used to transmit the sample container 20 loaded with the blood sample 30 placed in the sample storage device 100 to the sample measurement device 200. The first camera device 400 is used to perform a first shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and separated into the upper layer liquid 31, the middle layer liquid 32, and the lower layer liquid 33, from the oblique upper or oblique lower side of the middle layer liquid 32, before the sample measuring device 200 draws the upper layer liquid 31 from the sample container 20. The control device 500 is configured to: obtain a first target image based on the image captured by the first camera device 400 when performing the first shooting action; and output at least one of the following information based on the first target image: the first target image, which is used to characterize the determination result of whether the middle layer liquid 32 has a clot, and the determination result of the degree of coagulation of the blood sample 30. The first target image at least includes an image of the middle layer liquid 32, and the first target image is used as a basis for determining whether the middle layer liquid 32 has a clot and/or as a basis for determining the degree of coagulation of the blood sample 30.

As an embodiment, the first camera device 400 performs a first shooting action on the sample container 20, including: the first camera device 400 is used to shoot an image of the sample container 20 from the upper side of the intermediate layer of liquid 32 directly toward the sample container 20, with the camera optical axis forming a preset angle A with the horizontal direction, and the preset angle A is greater than or equal to 10° and less than or equal to 70°.

As an embodiment, the sample analysis system 10 further includes a second camera device, which is used to perform a second shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered before the first camera device 400 performs the first shooting action on the sample container 20. The control device 500 is further configured to: before obtaining the first target image, control one of the sample container 20 and the second camera device to rotate horizontally relative to the other around an axis MN perpendicular to the horizontal direction, and during the process of the sample container 20 and the second camera device rotating horizontally relative to the other around an axis MN perpendicular to the horizontal direction, control the second camera device to perform a second shooting action on the sample container 20, and obtain the target shooting orientation according to the image captured by the second camera device when performing the second shooting action. The control device 500 obtains the first target image in the following manner: controlling one of the sample container 20 and the first camera device 400 to rotate horizontally relative to the other around an axis MN perpendicular to the horizontal direction and stop at a target shooting position, and controlling the first camera device 400 to perform a first shooting action on the sample container 20 to obtain the first target image; wherein the second camera device and the first camera device 400 are the same camera device, or the second camera device and the first camera device 400 are two independent camera devices.

As an embodiment, the sample analysis system 10 further includes a third camera device 700, which is used to perform a third shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered, in a horizontal direction before the first camera device 400 performs the first shooting action on the sample container 20. The control device 500 is also configured to: before acquiring the first target image, first control the third camera device 700 to perform the third shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered. The control device 500 obtains the first target image by: controlling one of the sample container 20 and the first camera 400 to move relative to the other and stop at the target height position, controlling the first camera 400 to perform the first shooting action on the sample container 20, and obtaining the first target image according to the image captured by the first camera 400 when the first camera 400 performs the first shooting action. The third camera 700 and the first camera 400 are the same camera, or the third camera 700 and the first camera 400 are two independent camera devices.

As an embodiment, the sample analysis system 10 further includes a fourth camera device, which is used to perform a fourth shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifugally separated into the upper layer liquid 31, the middle layer liquid 32, and the lower layer liquid 33 before the sample measuring device 200 draws the upper layer liquid 31 from the sample container 20. The sample measuring device 200 includes a sample dispensing mechanism 220, a reagent dispensing mechanism 250, and an optical measuring mechanism 230. The sample dispensing mechanism 220 includes a sample needle and a needle blocking detection component, the sample needle is used to draw at least part of the upper layer liquid 31 from the sample container 20 after the first camera device 400 has performed the first shooting action and the fourth camera device has performed the fourth shooting action and distribute it to the reaction container, and the needle blocking detection component is used to detect a parameter used to characterize whether the sample needle is blocked during the sample aspiration process. The reagent dispensing mechanism 250 is used to draw at least part of the reagent from the reagent container and distribute it to the reaction container. The optical measurement mechanism 230 is used to perform optical measurement on the reaction liquid made of at least the blood sample 30 and the reagent in the reaction container. The control device 500 is also configured to: obtain a second target image including an image of the upper layer of liquid 31 according to the image captured by the fourth camera device performing the fourth shooting action; determine whether the sample needle is blocked according to the feedback information of the needle blocking detection component; determine whether the blood sample 30 is clotted and/or determine the degree of coagulation of the blood sample 30 according to at least two of the first target image, the second target image and the determination result of whether the sample needle is blocked.

As an implementation manner, the fourth camera device and the first camera device 400 are the same camera device, or the fourth camera device and the first camera device 400 are two independent camera devices.

The other parts of the sample analysis system 10 provided in this embodiment can refer to the first to tenth embodiments and will not be described in detail here.

Embodiment 12:

The sample analysis system 10 provided in this embodiment is different from that in the first embodiment mainly in that the emphasis of protection is different, which is specifically reflected in that: in the first embodiment, the emphasis is on protection, and the first camera device 400 performs a first shooting action to obtain an image that at least displays the interface liquid surface 321 or the interface liquid layer in a two-dimensional form and/or a three-dimensional form; while in the present embodiment, the emphasis is on protection, and the first camera device 400 performs a first shooting action on the sample container 20 from obliquely above or obliquely below the intermediate layer liquid 32 to obtain an image that at least includes the intermediate layer liquid 32.

Specifically, the sample analysis system 10 provided in this embodiment includes a sample storage device 100, a sample measurement device 200, a sample container transmission device 300, a first camera device 400, a reflector and a control device 500. The sample storage device 100 is at least used for placing a sample container 20 loaded with a blood sample 30 to achieve the loading of the blood sample 30. The sample measurement device 200 is used to absorb at least part of the upper layer liquid 31 from the sample container 20 loaded with the blood sample 30 after centrifugation and stratification into an upper layer liquid 31, an intermediate layer liquid 32 and a lower layer liquid 33, and distribute it to a reaction container for reaction and measurement, and the intermediate layer liquid 32 at least contains platelets and/or leukocytes. The sample container transmission device 300 is used to transmit the sample container 20 loaded with the blood sample 30 placed in the sample storage device 100 to the sample measurement device 200. The first camera device 400 is used to perform a first shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifugally separated into the upper layer liquid 31, the middle layer liquid 32, and the lower layer liquid 33 before the sample measuring device 200 draws the upper layer liquid 31 from the sample container 20. The reflector is used to: when the first camera device 400 performs the first shooting action, reflect the image at least including the middle layer liquid 32 to the first camera device 400; the first camera device 400 performs the first shooting action on the sample container 20 includes: the first camera device 400 shoots the image of the sample container 20 in the reflector toward the reflector. The control device 500 is configured to: obtain a first target image according to the image captured by the first camera device 400 when performing the first shooting action; and output at least one of the following information according to the first target image: the first target image is used to characterize the determination result of whether the middle layer liquid 32 has a clot, and the determination result of the degree of coagulation of the blood sample 30. The first target image at least includes an image of the intermediate layer liquid 32 , and the first target image is used as a basis for determining whether the intermediate layer liquid 32 has clots and/or as a basis for determining the degree of coagulation of the blood sample 30 .

As an implementation manner, the reflector is tilted relative to the horizontal direction, and the camera optical axis of the first camera device 400 is perpendicular to the horizontal direction when performing the first shooting action.

As an embodiment, the reflector is used to reflect the image of the sample container 20 from obliquely above or below the intermediate layer liquid 32 when the first camera device 400 performs the first shooting action; the first camera device 400 is used to capture the image of the sample container 20 in the reflector when performing the first shooting action.

As an embodiment, the sample analysis system 10 further includes a second camera device, which is used to perform a second shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered before the first camera device 400 performs the first shooting action on the sample container 20. The control device 500 is also configured to: before obtaining the first target image, control one of the sample container 20 and the second camera device to rotate horizontally relative to the other around an axis MN perpendicular to the horizontal direction, and during the process of the sample container 20 and the second camera device rotating horizontally relative to the other around the axis MN perpendicular to the horizontal direction, control the second camera device to shoot the sample container 20 and the second camera device horizontally. The control device 500 obtains the first target image by: controlling one of the sample container 20 and the first camera 400 to rotate horizontally relative to the other about an axis MN perpendicular to the horizontal direction and stop at the target shooting position, and controlling the first camera 400 to perform the first shooting action on the sample container 20 to obtain the first target image. The second camera and the first camera 400 are the same camera, or the second camera and the first camera 400 are two independent camera devices.

As an embodiment, the sample analysis system 10 further includes a third camera device 700, which is used to perform a third shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered in a horizontal direction before the first camera device 400 performs the first shooting action on the sample container 20. The control device 500 is further configured to: before acquiring the first target image, first control the third camera device 700 to perform a third shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifuged and layered, obtain the height position of the intermediate layer liquid 32 according to the image captured by the third camera device 700 performing the third shooting action, and obtain the target height position according to the height position of the intermediate layer liquid 32. The control device 500 obtains the first target image by: controlling one of the sample container 20 and the first camera device 400 to move relative to the other and stop at the target height position, controlling the first camera device 400 to perform the first shooting action on the sample container 20, and obtaining the first target image according to the image captured by the first camera device 400 performing the first shooting action. The third camera device 700 and the first camera device 400 are the same camera device, or the third camera device 700 and the first camera device 400 are two independent camera devices.

As an embodiment, the sample analysis system 10 further includes a fourth camera device, which is used to perform a fourth shooting action on the sample container 20 loaded with the blood sample 30 and after the blood sample 30 is centrifugally separated into the upper layer liquid 31, the middle layer liquid 32, and the lower layer liquid 33 before the sample measuring device 200 draws the upper layer liquid 31 from the sample container 20. The sample measuring device 200 includes a sample dispensing mechanism 220, a reagent dispensing mechanism 250, and an optical measuring mechanism 230. The sample dispensing mechanism 220 includes a sample needle and a needle blocking detection component, the sample needle is used to draw at least part of the upper layer liquid 31 from the sample container 20 after the first camera device 400 has performed the first shooting action and the fourth camera device has performed the fourth shooting action and distribute it to the reaction container, and the needle blocking detection component is used to detect a parameter used to characterize whether the sample needle is blocked during the sample aspiration process. The reagent dispensing mechanism 250 is used to draw at least part of the reagent from the reagent container and distribute it to the reaction container. The optical measurement mechanism 230 is used to perform optical measurement on the reaction liquid made of at least the blood sample 30 and the reagent in the reaction container. The control device 500 is also configured to: obtain a second target image including an image of the upper layer of liquid 31 according to the image captured by the fourth camera device performing the fourth shooting action; determine whether the sample needle is blocked according to the feedback information of the needle blocking detection component; determine whether the blood sample 30 is clotted and/or determine the degree of coagulation of the blood sample 30 according to at least two of the first target image, the second target image and the determination result of whether the sample needle is blocked.

As an implementation manner, the fourth camera device and the first camera device 400 are the same camera device, or the fourth camera device and the first camera device 400 are two independent camera devices.

The other parts of the sample analysis system 10 provided in this embodiment can refer to the first to tenth embodiments and will not be described in detail here.

The above description is only a preferred embodiment of the present invention, and does not limit the patent scope of the present invention. All equivalent structural changes made by using the contents of the present invention specification and drawings under the inventive concept of the present invention, or directly/indirectly applied in other related technical fields are included in the patent protection scope of the present invention.

Claims (32)

A sample analysis system, characterized in that it comprises: A sample storage device, the sample storage device is at least used for placing a sample container loaded with a blood sample to achieve the loading of the blood sample; A sample measuring device, the sample measuring device is used to draw at least part of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, a middle layer liquid, and a lower layer liquid, and distribute it to a reaction container for reaction and measurement, wherein the middle layer liquid at least contains platelets and/or leukocytes; a sample container transporting device, the sample container transporting device being used to transport the sample container placed in the sample storage device and loaded with the blood sample to the sample measuring device; a first camera device, the first camera device being used to perform a first photographing action on the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into the upper layer liquid, the middle layer liquid, and the lower layer liquid before the sample measuring device absorbs the upper layer liquid from the sample container, wherein there is a boundary liquid surface or boundary liquid layer between the middle layer liquid and the upper layer liquid; A control device, the control device being configured to: obtain a first target image according to the image captured by the first camera device when performing the first shooting action; output at least one of the following information according to the first target image: the first target image is used to characterize the determination result of whether the intermediate layer liquid has a clot, and is used to characterize the determination result of the degree of coagulation of the blood sample; Among them, the first target image at least includes an image showing the interface liquid surface or the interface liquid layer in a two-dimensional form and/or a three-dimensional form, and the first target image is used as a basis for judging whether the intermediate layer liquid has a clot and/or as a basis for determining the degree of coagulation of the blood sample. The sample analysis system according to claim 1, characterized in that: the outputting, based on the first target image, at least one of the following information: the first target image, a determination result for representing whether the intermediate layer liquid has a clot, a determination result for representing the degree of coagulation of the blood sample, comprises: outputting the first target image; Alternatively, the outputting of at least one of the following information based on the first target image: the first target image, a determination result for characterizing whether the intermediate layer liquid has a clot, and a determination result for characterizing the degree of coagulation of the blood sample, including: outputting the first target image, and outputting at least one of a determination result for characterizing whether the intermediate layer liquid has a clot and a determination result for characterizing the degree of coagulation of the blood sample. The sample analysis system according to claim 1, characterized in that: the sample analysis system further comprises a reflector, the reflector being used to: when the first camera device performs the first shooting action, reflect at least an image showing the interface liquid surface or interface liquid layer in a two-dimensional form and/or a three-dimensional form to the first camera device; The first camera device performs the first photographing action on the sample container, including: the first camera device photographs the image of the sample container in the reflector toward the reflector. The sample analysis system according to claim 3, characterized in that: the reflector is arranged to be inclined relative to the horizontal direction, and the camera optical axis of the first camera device when performing the first shooting action is perpendicular to the horizontal direction; and/or, The reflector is used to reflect the image of the sample container from obliquely above or below the intermediate layer liquid when the first camera device performs the first shooting action; the first camera device is used to capture the image of the sample container in the reflector when performing the first shooting action. The sample analysis system as described in claim 1 is characterized in that: the first camera device performs the first shooting action on the sample container, including: the first camera device shoots an image of the sample container directly toward the sample container from directly above, obliquely above, or obliquely below the intermediate layer of liquid. The sample analysis system as described in claim 5 is characterized in that: the first camera device performs the first shooting action on the sample container, including: the first camera device is used to shoot an image of the sample container from the upper side of the intermediate layer of liquid directly toward the sample container with the camera optical axis at a preset angle to the horizontal direction, and the preset angle is greater than or equal to 10° and less than or equal to 70°. The sample analysis system according to claim 1, characterized in that: the sample analysis system further comprises a second camera device, the second camera device being used to perform a second shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and stratified before the first camera device performs the first shooting action on the sample container; The control device is further configured to: before obtaining the first target image, control one of the sample container and the second camera device to rotate horizontally relative to the other around an axis perpendicular to the horizontal direction; during the process of the sample container and the second camera device rotating horizontally relative to the other around an axis perpendicular to the horizontal direction, control the second camera device to perform the second shooting action on the sample container, and obtain the target shooting direction according to the image captured by the second camera device performing the second shooting action. Bit; The control device obtains the first target image, including: controlling one of the sample container and the first camera device to rotate horizontally relative to the other about an axis perpendicular to the horizontal direction and stop at the target shooting orientation, and controlling the first camera device to perform the first shooting action on the sample container to obtain the first target image; The second camera device and the first camera device are the same camera device, or the second camera device and the first camera device are two independent camera devices. The sample analysis system as described in claim 7 is characterized in that: the control device obtains the target shooting orientation, including: controlling one of the sample container and the second camera device to rotate relative to the other about an axis perpendicular to the horizontal direction by a first preset stroke, the first preset stroke being greater than or equal to 360°, and in the process of horizontally rotating one of the sample container and the second camera device relative to the other about an axis perpendicular to the horizontal direction by the first preset stroke, controlling the second camera device to capture a first number of images of the sample container to perform the second shooting action, and determining the shooting orientation corresponding to an image of the first number of images of the sample container that displays the smallest area of an obstruction on the sample container or does not display the obstruction on the sample container as the target shooting orientation; or, The control device obtains the target shooting orientation, including: controlling one of the sample container and the second camera device to rotate relative to the other around an axis perpendicular to the horizontal direction, and during the process of one of the sample container and the second camera device rotating relative to the other around an axis perpendicular to the horizontal direction, controlling the second camera device to capture images of the sample container at first preset time intervals to perform the second shooting action; when an image captured by the second camera device shows that the area of the obstruction on the sample container is less than or equal to a preset threshold or the obstruction on the sample container is not displayed, the shooting orientation corresponding to the image showing that the area of the obstruction on the sample container is less than or equal to the preset threshold or the obstruction on the sample container is not displayed is determined as the target shooting orientation. The sample analysis system as described in claim 1 is characterized in that: the control device obtains the first target image, including: controlling one of the sample container and the first camera device to rotate relative to the other around an axis perpendicular to the horizontal direction, and during the process of one of the sample container and the first camera device rotating relative to the other around the axis perpendicular to the horizontal direction, controlling the first camera device to capture an image of the sample container to perform the first shooting action, and using an image captured by the first camera device during the process of one of the sample container and the first camera device rotating horizontally relative to the other around the axis perpendicular to the horizontal direction as the first target image. The sample analysis system as described in claim 9 is characterized in that: the control device obtains the first target image, including: controlling one of the sample container and the first camera device to rotate relative to the other about an axis perpendicular to the horizontal direction for a second preset stroke, and in the process of rotating one of the sample container and the first camera device relative to the other about the axis perpendicular to the horizontal direction for the second preset stroke, controlling the first camera device to capture a second number of images of the sample container to perform the first capturing action, and using an image of the second number of images of the sample container that has the smallest area of occlusion on the sample container or does not display the occlusion on the sample container as the first target image; or The control device obtains the first target image, including: controlling one of the sample container and the first camera device to rotate relative to the other around an axis perpendicular to the horizontal direction, and during the process of one of the sample container and the first camera device rotating relative to the other around an axis perpendicular to the horizontal direction, controlling the first camera device to capture images of the sample container at second preset time intervals to perform the first shooting action; when an image captured by the first camera device shows that the area of the occlusion on the sample container is less than or equal to a preset threshold or the occlusion on the sample container is not displayed, an image in which the area of the occlusion on the sample container is less than or equal to the preset threshold or the occlusion on the sample container is not displayed is displayed as the first target image. The sample analysis system according to any one of claims 1 to 10, characterized in that: the sample analysis system further comprises a third camera device, the third camera device being used to perform a third shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and stratified in a horizontal direction before the first camera device performs the first shooting action on the sample container; The control device is further configured to: before acquiring the first target image, first control the third camera device to perform the third shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and layered, obtain the height position of the interface liquid surface or the interface liquid layer according to the image captured by the third camera device when performing the third shooting action, and obtain the target height position according to the height position of the interface liquid surface or the interface liquid layer; The control device obtains the first target image, including: controlling one of the sample container and the first camera to move relative to the other and stop at the target height position, controlling the first camera to perform the first shooting action on the sample container, and obtaining the first target image according to an image captured by the first camera when performing the first shooting action; The third camera device and the first camera device are the same camera device, or the third camera device and the first camera device are two independent camera devices. The sample analysis system according to claim 11, characterized in that: the control device is further configured to: control the third camera device to perform the third shooting action with the first field of view and the first object resolution; control the first camera device to perform the third shooting action with the second field of view and the second object resolution; The first shooting action is performed at an object space resolution, wherein the first field of view is larger than the second field of view, and the first object space resolution is smaller than the second object space resolution; And/or, the first camera device and the third camera device are the same camera device, and the first camera device includes an adjusting component, and the adjusting component is at least used to adjust the shooting angle of the first camera device; the control device is also configured to: first control the first camera device to perform the third shooting action on the sample container in a horizontal direction, then control the adjusting component to adjust the shooting angle of the first camera device, and then control the first camera device after adjusting the shooting angle to perform the first shooting action on the sample container from obliquely above the intermediate layer of liquid. The sample analysis system according to any one of claims 1 to 10, characterized in that: the control device is further configured to: obtain a determination result for characterizing whether the intermediate layer of liquid has a clot based on at least one of the following features: whether there is a feature for characterizing a depression in the image of the interface liquid surface or the interface liquid layer, whether there is a feature for characterizing a protrusion in the image of the interface liquid surface or the interface liquid layer; and/or, The control device is also configured to obtain a determination result characterizing the degree of coagulation of the blood sample based on at least one of the following features: the number of features characterizing depressions in the image of the interface liquid surface or the interface liquid layer, the number of features characterizing protrusions in the image of the interface liquid surface or the interface liquid layer, and the size of features characterizing depressions in the image of the interface liquid surface or the interface liquid layer. The sample analysis system according to any one of claims 1 to 10, characterized in that: the sample container transmission device comprises a first conveying track, a first sample container scheduling mechanism and a sample container transfer device, the first conveying track is used to convey a sample holder having a single first container position, the first container position is used to place a single sample container; The first sample scheduling mechanism is used to schedule the sample container placed in the sample storage device and loaded with the blood sample to the sample seat located on the first conveying track; The sample container transfer device comprises a sample seat scheduling mechanism, a second sample container scheduling mechanism and a sample rack scheduling mechanism, wherein the sample seat scheduling mechanism is at least used to transport the sample seat transported by the first transport track to the sample container transfer device to a rack position, and the second sample container scheduling mechanism is used to schedule the sample container on the sample seat at the rack position to a sample rack provided by the sample rack scheduling mechanism, wherein the sample rack has at least two second container positions, each of which is used to place a single sample container; and the sample rack scheduling mechanism is used to schedule the sample rack loaded with the sample container and the blood sample in the sample container to the sample measurement device; The first camera device is used to perform the first shooting action on the sample container transferred by the sample container transfer device to the first shooting position, and the first shooting position is located between the first conveying track and the sample measuring device along the path along which the sample container is transferred by the sample container transfer device; Alternatively, the first camera device is used to perform the first shooting action on the sample container transported by the first conveying track to the first shooting position, and the first shooting position is located between the first sample scheduling mechanism and the sample container transfer device along the path along which the sample container is transported by the first conveying track; Alternatively, the first camera device is used to perform the first shooting action on the sample container transported by the sample measuring device to a first shooting position, and the first shooting position is located before the sample aspirating position of the sample measuring device along the path of the sample measuring device transporting the sample container. The sample analysis system according to any one of claims 1 to 10, characterized in that: the sample container transmission device comprises a second conveying track and a third sample container scheduling mechanism, the third sample container scheduling mechanism is used to schedule the sample container placed in the sample storage device and loaded with the blood sample to the second conveying track, and the second conveying track is used to transport the sample container to the sample measurement device; The first camera device is used to perform the first shooting action on the sample container transported by the second transport track to the first shooting position, and the first shooting position is located between the third sample container scheduling mechanism and the sample measurement device along the transport path of the second transport track; Alternatively, the first camera device is used to perform the first shooting action on the sample container dispatched to the first shooting position by the third sample container dispatching mechanism, and the first shooting position is located between the sample storage device and the second conveying track along the dispatching path of the third sample container dispatching mechanism; Alternatively, the first camera device is used to perform the first shooting action on the sample container transported by the sample measuring device to a first shooting position, and the first shooting position is located before the sample aspirating position of the sample measuring device along the path of the sample measuring device transporting the sample container. The sample analysis system according to any one of claims 1 to 10, characterized in that: the sample analysis system further comprises a centrifugal device, the centrifugal device being used to centrifuge the sample container loaded with the blood sample so that the blood sample is centrifugally separated into the upper layer of liquid, the middle layer of liquid, and the lower layer of liquid; The sample storage device is used for placing a sample container loaded with a blood sample and not subjected to a centrifugal operation to achieve the uncentrifuged blood sample The invention relates to a method for loading a sample of the blood sample, and a method for placing a sample container loaded with a blood sample and subjected to a centrifugal operation into the sample container to achieve loading of the centrifuged blood sample; The sample container transmission device comprises a third conveying track and a fourth sample container scheduling mechanism, wherein the fourth sample container scheduling mechanism is used to schedule the sample container placed in the sample storage device and loaded with the blood sample to the third conveying track, and the third conveying track is used to convey the sample container loaded with the uncentrifuged blood sample to the centrifuge device for centrifugation and to convey the sample container loaded with the centrifuged blood sample to the sample measuring device; The first camera device is used to perform the first shooting action on the sample container transported by the third transport track to the first shooting position, and the first shooting position is located between the centrifugal device and the sample measuring device along the transport path of the third transport track; Alternatively, the first camera device is used to perform the first shooting action on the sample container transported by the sample measuring device to a first shooting position, and the first shooting position is located before the sample aspirating position of the sample measuring device along the path of the sample measuring device transporting the sample container. The sample analysis system according to any one of claims 1 to 10, characterized in that: the sample container transmission device comprises a sample suction delivery channel and a fifth sample container scheduling mechanism, the sample storage device is used for placing a sample container loaded with a blood sample and subjected to a centrifugal operation to achieve the loading of the centrifuged blood sample, the fifth sample scheduling mechanism is used to schedule the sample container loaded with the blood sample placed in the sample storage device to the sample suction delivery channel, and the sample measurement device is used to absorb at least part of the upper layer of liquid from the sample container in the sample suction delivery channel and distribute it to a reaction container for reaction and measurement; The first camera device is used to perform the first shooting action on the sample container dispatched to the first shooting position by the fifth sample container dispatching mechanism, and the first shooting position is located between the sample storage device and the sample suction and delivery channel along the dispatching path of the fifth sample dispatching mechanism; Alternatively, the first camera device is used to perform the first shooting action on the sample container transported by the sample suction and delivery channel to a first shooting position, and the first shooting position is located before the sample suction position of the sample measurement device along the path of the sample suction and delivery channel for transporting the sample container. The sample analysis system according to any one of claims 1 to 10 is characterized in that: the control device is also configured to: based on the first target image, display at least one of the first target image, the determination result for characterizing whether the intermediate layer liquid has a clot, and the determination result for characterizing the degree of coagulation of the blood sample in a sample test report and/or transmit it to a laboratory information management system that is communicatively connected to the sample analysis system. The sample analysis system as described in claim 18 is characterized in that: the control device is also configured to: determine the degree of coagulation of the blood sample based on the first target image, and use at least two different identification methods for at least two blood samples with different degrees of coagulation, respectively, to display them in the sample test report and/or transmit them to the laboratory information management system. The sample analysis system according to any one of claims 1 to 10, characterized in that: the sample measurement device includes a first display, the first display is used to display at least the measurement item information of the blood sample in the sample measurement device, and the control device is further configured to: display at least one of the following information on the display interface of the first display: the first target image, used to represent the determination result of whether the intermediate layer liquid has a clot, used to represent the determination result of the degree of coagulation of the blood sample; and/or, The sample analysis system also includes a second display, which is independently arranged from the sample measuring device, and the second display is at least used to display the storage information of the blood sample in the sample storage device and the information of the blood sample transmitted by the sample container transmission device. The control device is also configured to: display at least one of the following information on the display interface of the second display: the first target image, which is used to characterize the judgment result of whether the intermediate layer liquid has a clot, and which is used to characterize the judgment result of the degree of coagulation of the blood sample. The sample analysis system according to any one of claims 1 to 10, characterized in that: the sample analysis system further comprises a fourth camera device, the fourth camera device being used to perform a fourth shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into the upper layer of liquid, the middle layer of liquid, and the lower layer of liquid before the sample measuring device draws the upper layer of liquid from the sample container; The sample assay device comprises a sample dispensing mechanism, a reagent dispensing mechanism and an assay mechanism; The sample dispensing mechanism comprises a sample needle and a needle blocking detection component, wherein the sample needle is used to absorb at least part of the upper layer of liquid from the sample container after the first camera device performs the first shooting action and the fourth camera device performs the fourth shooting action and distributes it to the reaction container, and the needle blocking detection component is used to detect a parameter used to characterize whether a needle blocking phenomenon occurs during the sample aspiration process of the sample needle; The reagent dispensing mechanism is used to draw at least part of the reagent from the reagent container and dispense it into the reaction container; The measuring mechanism is used to measure the reaction solution made of at least the blood sample and the reagent in the reaction container; The control device is further configured to: obtain a second target image including the upper liquid image based on the image captured by the fourth camera device during the fourth shooting action; determine whether the sample needle is blocked based on feedback information from the needle blocking detection component; and determine whether the sample needle is blocked based on at least two of the first target image, the second target image, and the determination result of whether the sample needle is blocked. or, determining whether the blood sample has clots and/or determining the extent of coagulation of the blood sample; The fourth camera device and the first camera device are the same camera device, or the fourth camera device and the first camera device are two independent camera devices. The sample analysis system according to any one of claims 1 to 10, characterized in that: the sample measuring device comprises a sample dispensing mechanism and a measuring mechanism, the sample dispensing mechanism is used to absorb at least part of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, an intermediate layer liquid, and a lower layer liquid, and distribute it to the reaction container, the intermediate layer liquid containing platelets and/or leukocytes; the measuring mechanism is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid and a reagent; The control device is also configured to: When a first sample container loaded with the blood sample and having abnormal clots in the blood sample is placed in the sample storage device, the sample container transfer device is controlled to transfer the first sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the first sample container located at the first shooting position, and the sample container transfer device is controlled to transfer the first sample container after the first shooting action is completed and the upper layer of liquid loaded therein is not measured by the measuring mechanism to the first storage space; When a second sample container loaded with the blood sample and having no abnormal clot phenomenon in the blood sample is placed in the sample storage device, the sample container transmission device is controlled to transmit the second sample container loaded with the blood sample and after the blood sample is centrifuged and stratified into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the second sample container located at the first shooting position, the sample container transmission device is controlled to transmit the second sample container after completing the first shooting action to the sample measurement device, the sample distribution mechanism is controlled to absorb at least part of the upper layer of liquid from the second sample container and distribute it to the first reaction container, and the measurement mechanism is controlled to measure the first test liquid made of at least the upper layer of liquid distributed to the first reaction container and the reagent; Wherein, the first storage space is located in the sample storage device, or is located beside the sample container transmission device, or is located below the sample container transmission device, or is located above the sample container transmission device. The sample analysis system as claimed in claim 22, characterized in that: the step of controlling the sample container transmission device to transmit the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transmission device to transmit the first sample container after the first shooting action is completed and the upper layer liquid has not been transmitted by the sample container transmission device to the sample measuring device to the first storage space; Alternatively, the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and the upper layer liquid has not been sucked out of it by the sample dispensing mechanism to the first storage space; Alternatively, the sample measuring device further includes a reagent dispensing mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least part of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and before the reagent dispensing mechanism distributes the reagent to the second reaction container to the first storage space; Alternatively, the sample measuring device further includes an incubation mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and without the incubation mechanism incubating the liquid in the second reaction container at least containing the upper layer liquid distributed from the first sample container to the second reaction container to the first storage space; Alternatively, the sample measuring device further includes a reagent dispensing mechanism and an incubation mechanism, and the controlling the sample container transmission device to transmit the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transmission device to transmit the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, controlling the incubation mechanism to incubate the liquid in the second reaction container at least containing the upper layer liquid distributed from the first sample container to the second reaction container, controlling the reagent dispensing mechanism to distribute the reagent to the second reaction container, and controlling the sample container transmission device to output from the sample measuring device and the upper layer liquid loaded therein has not been measured by the measuring mechanism The first sample container containing at least the upper layer liquid distributed into the second reaction container and the second test liquid of the reagent for measurement is transferred to the first storage space. The sample analysis system as described in claim 22 is characterized in that: when a first sample container loaded with the blood sample and in which an abnormal clotting phenomenon exists is placed in the sample storage device, after controlling the first camera device to perform the first shooting action on the first sample container located at the first shooting position, the control device is also configured to: output prompt information for indicating that the blood sample in the first sample container has an abnormal clotting phenomenon. A sample analysis system, characterized in that it comprises: A sample storage device, the sample storage device is at least used for placing a sample container loaded with a blood sample to achieve the loading of the blood sample; A sample measuring device, the sample measuring device is used to draw at least part of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, a middle layer liquid, and a lower layer liquid, and distribute it to a reaction container for reaction and measurement, wherein the middle layer liquid at least contains platelets and/or leukocytes; a sample container transporting device, the sample container transporting device being used to transport the sample container placed in the sample storage device and loaded with the blood sample to the sample measuring device; a first camera device, the first camera device being used to perform a first photographing action on the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into the upper layer liquid, the middle layer liquid, and the lower layer liquid, from obliquely above or obliquely below the middle layer liquid, before the sample measuring device absorbs the upper layer liquid from the sample container; A control device, the control device being configured to: obtain a first target image according to the image captured by the first camera device when performing the first shooting action; output at least one of the following information according to the first target image: the first target image is used to characterize the determination result of whether the intermediate layer liquid has a clot, and is used to characterize the determination result of the degree of coagulation of the blood sample; The first target image at least includes an image of the intermediate layer of liquid, and the first target image is used as a basis for determining whether the intermediate layer of liquid has clots and/or as a basis for determining the degree of coagulation of the blood sample. The sample analysis system according to claim 25, characterized in that: the first camera device performing the first shooting action on the sample container comprises: the first camera device is used to shoot an image of the sample container from the upper side of the intermediate layer of liquid directly toward the sample container in a posture where the camera optical axis forms a preset angle with the horizontal direction, and the preset angle is greater than or equal to 10° and less than or equal to 70°; And/or, the sample analysis system further comprises a second camera device, wherein the second camera device is used to perform a second shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and stratified, before the first camera device performs the first shooting action on the sample container; the control device is further configured to: before obtaining the first target image, control one of the sample container and the second camera device to rotate horizontally relative to the other around an axis perpendicular to the horizontal direction, and during the process of the horizontal rotation of one of the sample container and the second camera device relative to the other around an axis perpendicular to the horizontal direction, control the second camera device to The sample container performs the second shooting action, and obtains a target shooting orientation based on an image captured by the second camera device when performing the second shooting action; the control device obtains the first target image in the following manner: controlling one of the sample container and the first camera device to rotate horizontally relative to the other around an axis perpendicular to the horizontal direction and stop at the target shooting orientation, and controlling the first camera device to perform the first shooting action on the sample container to obtain the first target image; wherein the second camera device and the first camera device are the same camera device, or the second camera device and the first camera device are two independent camera devices. The sample analysis system according to claim 25 or 26, characterized in that: the sample measuring device comprises a sample dispensing mechanism and a measuring mechanism, the sample dispensing mechanism is used to absorb at least part of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, an intermediate layer liquid, and a lower layer liquid, and distribute it to the reaction container, the intermediate layer liquid containing platelets and/or leukocytes; the measuring mechanism is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid and a reagent; The control device is also configured to: When a first sample container loaded with the blood sample and having abnormal clots in the blood sample is placed in the sample storage device, the sample container transfer device is controlled to transfer the first sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the first sample container located at the first shooting position, and the sample container transfer device is controlled to transfer the first sample container after the first shooting action is completed and the upper layer of liquid loaded therein is not measured by the measuring mechanism to the first storage space; When a second sample container loaded with the blood sample and having no abnormal clot phenomenon in the blood sample is placed in the sample storage device, the sample container transfer device is controlled to transfer the second sample container loaded with the blood sample and having the blood sample centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, and the first camera device is controlled to focus on the second sample container at the first shooting position. The second sample container at a shooting position performs the first shooting action, controls the sample container transport device to transport the second sample container after the first shooting action to the sample measuring device, controls the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the second sample container and distribute it to the first reaction container, and controls the measuring mechanism to measure the first liquid to be tested which is made of at least the upper layer liquid distributed to the first reaction container and a reagent; Wherein, the first storage space is located in the sample storage device, or is located beside the sample container transmission device, or is located below the sample container transmission device, or is located above the sample container transmission device. The sample analysis system as claimed in claim 27, characterized in that: the step of controlling the sample container transmission device to transmit the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transmission device to transmit the first sample container after the first shooting action is completed and the upper layer liquid has not been transmitted by the sample container transmission device to the sample measuring device to the first storage space; Alternatively, the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and the upper layer liquid has not been sucked out of it by the sample dispensing mechanism to the first storage space; Alternatively, the sample measuring device further includes a reagent dispensing mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least part of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and before the reagent dispensing mechanism distributes the reagent to the second reaction container to the first storage space; Alternatively, the sample measuring device further includes an incubation mechanism, and the controlling the sample container transporting device to transport the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space comprises: controlling the sample container transporting device to transport the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, and controlling the sample container transporting device to transport the first sample container output from the sample measuring device and without the incubation mechanism incubating the liquid in the second reaction container at least containing the upper layer liquid distributed from the first sample container to the second reaction container to the first storage space; Alternatively, the sample measuring device further includes a reagent dispensing mechanism and an incubation mechanism, and the control of the sample container transmission device to transfer the first sample container after the first shooting action is completed and the upper layer liquid loaded therein has not been measured by the measuring mechanism to the first storage space includes: controlling the sample container transmission device to transfer the first sample container after the first shooting action is completed to the sample measuring device, controlling the sample dispensing mechanism to absorb at least a portion of the upper layer liquid from the first sample container and distribute it to a second reaction container, controlling the incubation mechanism to incubate the liquid in the second reaction container that at least contains the upper layer liquid distributed from the first sample container to the second reaction container, controlling the reagent dispensing mechanism to distribute the reagent to the second reaction container, and controlling the sample container transmission device to transfer the first sample container that is output from the sample measuring device and the second liquid to be tested that at least contains the upper layer liquid distributed to the second reaction container and the reagent has not been measured by the measuring mechanism to the first storage space. A sample analysis system, characterized in that it comprises: A sample storage device, the sample storage device is at least used for placing a sample container loaded with a blood sample to achieve the loading of the blood sample; A sample measuring device, the sample measuring device is used to draw at least part of the upper layer liquid from the sample container containing the blood sample after centrifugation into an upper layer liquid, a middle layer liquid, and a lower layer liquid, and distribute it to a reaction container for reaction and measurement, wherein the middle layer liquid at least contains platelets and/or leukocytes; a sample container transporting device, the sample container transporting device being used to transport the sample container placed in the sample storage device and loaded with the blood sample to the sample measuring device; a first camera device, the first camera device being used to perform a first photographing action on the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into the upper layer liquid, the middle layer liquid, and the lower layer liquid before the sample measuring device absorbs the upper layer liquid from the sample container; a reflector, the reflector being used to: when the first camera device performs the first shooting action, reflect the image at least including the intermediate layer of liquid to the first camera device; the first camera device performing the first shooting action on the sample container comprises: the first camera device shoots the image of the sample container in the reflector toward the reflector; A control device, the control device being configured to: obtain a first target image according to the image captured by the first camera device when performing the first shooting action; output at least one of the following information according to the first target image: the first target image is used to characterize the determination result of whether the intermediate layer liquid has a clot, and is used to characterize the determination result of the degree of coagulation of the blood sample; The first target image at least includes an image of the intermediate layer of liquid, and the first target image is used as a basis for determining whether the intermediate layer of liquid has clots and/or as a basis for determining the degree of coagulation of the blood sample. The sample analysis system according to claim 29, characterized in that: the reflector is arranged to be inclined relative to the horizontal direction, and the camera optical axis when the first camera device performs the first shooting action is perpendicular to the horizontal direction; and/or, The reflector is used to reflect the image of the sample container from obliquely above or below the intermediate layer liquid when the first camera device performs the first shooting action; the first camera device is used to capture the image of the sample container in the reflector when performing the first shooting action. The sample analysis system as described in claim 29 is characterized in that: the sample analysis system further includes a second camera device, and the second camera device is used to perform a second shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and stratified before the first camera device performs the first shooting action on the sample container; the control device is also configured to: before obtaining the first target image, control one of the sample container and the second camera device to rotate horizontally relative to the other around an axis perpendicular to the horizontal direction, and during the process of the sample container and the second camera device rotating horizontally relative to the other around an axis perpendicular to the horizontal direction, Controlling the second camera to perform the second shooting action on the sample container, and obtaining a target shooting position according to an image captured by the second camera when performing the second shooting action; the control device obtaining the first target image comprises: controlling one of the sample container and the first camera to rotate horizontally relative to the other about an axis perpendicular to the horizontal direction and stop at the target shooting position, and controlling the first camera to perform the first shooting action on the sample container to obtain the first target image; wherein the second camera and the first camera are the same camera, or the second camera and the first camera are two independent camera devices; And/or, the sample analysis system further includes a third camera device, the third camera device is used to perform a third shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and layered in a horizontal direction before the first camera device performs the first shooting action on the sample container; the control device is further configured to: before acquiring the first target image, first control the third camera device to perform the third shooting action on the sample container loaded with the blood sample and after the blood sample is centrifuged and layered, obtain the height position of the intermediate layer liquid according to the image captured by the third camera device performing the third shooting action, and obtain the target height position according to the height position of the intermediate layer liquid; the control device obtaining the first target image includes: controlling one of the sample container and the first camera device to move relative to the other and stop at the target height position, controlling the first camera device to perform the first shooting action on the sample container, and obtaining the first target image according to the image captured by the first camera device performing the first shooting action; wherein the third camera device and the first camera device are the same camera device, or the third camera device and the first camera device are two independent camera devices. The sample analysis system according to any one of claims 29 to 31, characterized in that: the sample measuring device comprises a sample dispensing mechanism and a measuring mechanism, the sample dispensing mechanism is used to absorb at least part of the upper layer liquid from the sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer liquid, an intermediate layer liquid, and a lower layer liquid, and distribute it to the reaction container, the intermediate layer liquid containing platelets and/or leukocytes; the measuring mechanism is used to measure the test liquid in the reaction container made of at least the absorbed upper layer liquid and a reagent; The control device is also configured to: When a first sample container loaded with the blood sample and having abnormal clots in the blood sample is placed in the sample storage device, the sample container transfer device is controlled to transfer the first sample container loaded with the blood sample and after the blood sample is centrifuged and separated into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the first sample container located at the first shooting position, and the sample container transfer device is controlled to transfer the first sample container after the first shooting action is completed and the upper layer of liquid loaded therein is not measured by the measuring mechanism to the first storage space; When a second sample container loaded with the blood sample and having no abnormal clot phenomenon in the blood sample is placed in the sample storage device, the sample container transmission device is controlled to transmit the second sample container loaded with the blood sample and after the blood sample is centrifuged and stratified into an upper layer of liquid, a middle layer of liquid, and a lower layer of liquid to the first shooting position, the first camera device is controlled to perform the first shooting action on the second sample container located at the first shooting position, the sample container transmission device is controlled to transmit the second sample container after completing the first shooting action to the sample measurement device, the sample distribution mechanism is controlled to absorb at least part of the upper layer of liquid from the second sample container and distribute it to the first reaction container, and the measurement mechanism is controlled to measure the first test liquid made of at least the upper layer of liquid distributed to the first reaction container and the reagent; Wherein, the first storage space is located in the sample storage device, or is located beside the sample container transmission device, or is located below the sample container transmission device, or is located above the sample container transmission device.