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WO2025084811A1 - Dispositif de pulvérisation de fluide caloporteur - Google Patents

Dispositif de pulvérisation de fluide caloporteur Download PDF

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Publication number
WO2025084811A1
WO2025084811A1 PCT/KR2024/015767 KR2024015767W WO2025084811A1 WO 2025084811 A1 WO2025084811 A1 WO 2025084811A1 KR 2024015767 W KR2024015767 W KR 2024015767W WO 2025084811 A1 WO2025084811 A1 WO 2025084811A1
Authority
WO
WIPO (PCT)
Prior art keywords
coolant
heater
injection device
cartridge
temperature
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/KR2024/015767
Other languages
English (en)
Korean (ko)
Inventor
박부성
노경관
이철호
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Recensmedical Inc
Original Assignee
Recensmedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020240123608A external-priority patent/KR20250057629A/ko
Application filed by Recensmedical Inc filed Critical Recensmedical Inc
Publication of WO2025084811A1 publication Critical patent/WO2025084811A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M19/00—Local anaesthesia; Hypothermia

Definitions

  • the present disclosure relates to a coolant injection device, and more specifically, to a coolant injection device including a temperature regulator for heating a coolant and the temperature regulator, and injecting a coolant heated from the temperature regulator.
  • the technology that cools the temperature of the target area to a specific temperature by spraying a coolant on the target area not only produces a skin beauty effect in itself, but can also be utilized in various ways, such as by relieving pain in procedures such as lasers, botox, and fillers, and research and development on this is actively being conducted.
  • the coolant sprayed on the target area is stored in a coolant container, and the coolant released from the coolant container when sprayed can rapidly drop in temperature as it is sprayed at atmospheric pressure. If the coolant at a rapidly low temperature reaches the skin, there is a risk that the target area, such as the skin, will be supercooled and skin necrosis may occur. Therefore, it is necessary to heat the coolant appropriately so that the temperature of the sprayed coolant does not drop excessively.
  • the heat transfer efficiency supplied to the coolant must be high. In order to increase the heat transfer efficiency, a lot of heat energy must be transferred to the coolant for a certain period of time. Accordingly, a heating device that enables a lot of heat energy to be transferred to the coolant for a certain period of time is required.
  • the present disclosure seeks to provide a temperature regulator having high heat transfer efficiency performance for a coolant.
  • the present disclosure seeks to provide a coolant injection device including a temperature controller capable of efficiently heating the coolant.
  • a coolant injection device for injecting a coolant comprises: a cartridge for providing the coolant; a nozzle fluidly connected to the cartridge and injecting the coolant provided from the cartridge to the target area; a heater interposed between the cartridge and the nozzle for heating the coolant transferred from the cartridge to the nozzle; and a valve interposed between the cartridge and the nozzle for allowing the coolant discharged from the cartridge to be transferred to the nozzle; wherein the heater can be disposed between the valve and the cartridge such that the coolant reaches the valve after being heated.
  • a coolant injection device for injecting a coolant provided from a coolant storage comprises: a nozzle for injecting the coolant provided from the coolant storage into the target area; a heater fluidly connected to the nozzle for heating the coolant transferred to the nozzle; and a valve fluidly connected to the nozzle for allowing the coolant to be transferred to the nozzle; wherein the heater may be positioned farther from the nozzle than the valve so that the coolant, after being heated, passes through the valve and is transferred to the nozzle.
  • a coolant injection device for injecting a coolant comprises: a cartridge for providing the coolant; a nozzle fluidly connected to the cartridge and for injecting the coolant provided from the cartridge to the target area; and a heater interposed between the cartridge and the nozzle for heating the coolant provided from the cartridge; wherein the heater comprises: a body, wherein the body includes a first surface, a second surface opposite the first surface, a third surface perpendicular to the first surface and the second surface, and a fourth surface opposite the third surface, the third surface being closer to the cartridge than the fourth surface, and the fourth surface being closer to the nozzle than the third surface; a first thermoelectric element attached to the first surface of the body; and a second thermoelectric element attached to a second surface of the body; wherein the body includes a plurality of flow paths forming a portion of a route along which the coolant is transported from the cartridge to the nozzle, each of the plurality of flow paths having a cylindrical shape extending from the third surface to the
  • a coolant injection device for injecting a coolant comprises: a cartridge for providing the coolant; a nozzle fluidly connected to the cartridge and injecting the coolant provided from the cartridge to the target area; and a heater interposed between the cartridge and the nozzle for heating the coolant provided from the cartridge; wherein the heater comprises: a body providing a space in which the coolant is heated, wherein the body forms at least a portion of a route through which the coolant flows and includes a flow path extending from one end of the body to the other end of the body; a first thermoelectric element and a second thermoelectric element arranged on a first portion of an outer surface of the body and configured to provide heat to the coolant through the body; wherein the heater comprises: a first sealing member arranged within one end of the body to prevent a coolant flowing into the body from the cartridge from leaking out of the route; A second sealing member arranged inside the other end of the body to prevent a coolant flowing out of the nozzle from the body from flowing out
  • the third portion is different from the first portion and the third portion, and is closer to the other end of the body than the first portion; further comprising: the first sealing member protrudes toward the cartridge more than the first insulating member, the second sealing member protrudes toward the nozzle more than the second insulating member, and when pressure is applied toward the central axis of the body, the length variability of the first sealing member and the second sealing member can be greater than the length variability of the first insulating member and the second insulating member.
  • a coolant injection device for injecting a coolant comprises: a cartridge for providing the coolant; a nozzle fluidly connected to the cartridge and injecting the coolant provided from the cartridge to the target area; a heater interposed between the cartridge and the nozzle for heating the coolant provided from the cartridge; a valve fluidly connected between the heater and the cartridge to allow the coolant provided from the cartridge to be transferred to a flow path of the heater; a valve connecting portion surrounding at least a portion of the heater and fluidly connecting the valve and the heater; and a nozzle connecting portion surrounding at least a portion of the heater and fluidly connecting the nozzle and the heater; wherein the heater comprises: a body providing a space in which the coolant is heated, wherein the body forms at least a portion of a route through which the coolant flows and includes a flow path extending from one end of the body to the other end of the body; A first thermoelectric element and a second thermoelectric element are disposed on a first portion of an outer surface of the body and
  • a temperature controller having high heat transfer efficiency for a coolant and being relatively easy to process can be produced.
  • a temperature controller when machining each component of a coolant injection device, even if a machining tolerance occurs, a temperature controller can be stably assembled into the coolant injection device while maintaining insulation between parts.
  • the sealing effect of both ends of the temperature controller can be increased, thereby reducing the coolant passing through the temperature controller from leaking to an unintended location.
  • power consumption of a coolant injection device can be reduced.
  • FIGS. 1 and 2 are drawings showing a coolant injection system according to an embodiment of the present disclosure.
  • FIG. 3 is a drawing showing the configurations of a coolant injection device according to an embodiment of the present disclosure.
  • FIGS. 4 and 5 are drawings showing the structure of a temperature controller.
  • FIGS. 6 to 8 are drawings showing a temperature controller according to Embodiment 1 of the present disclosure.
  • Figure 9 is experimental data for proving the heating efficiency of a temperature controller according to Example 1 of the present disclosure.
  • FIG. 10 is a drawing showing the configuration of a coolant injection device applicable to Example 2 of the present disclosure.
  • Figure 11 is a drawing to explain a problem when a temperature controller is assembled to a coolant injection device.
  • Figures 12 to 17 are drawings for explaining a temperature controller according to Example 2.
  • Figure 18 is a drawing for explaining the fluid connection relationship between components included in a conventional coolant injection device.
  • FIG. 19 is a drawing for explaining the fluid connection relationship between components included in a coolant injection device according to Example 3.
  • Figure 20 is experimental data measuring the power consumption of a coolant injection device according to Example 3.
  • a particular process sequence may be performed in a different order than the one described.
  • two processes described in succession may be performed substantially simultaneously, or in a reverse order from the one described.
  • a film, region, component, etc. when it is said that a film, region, component, etc. are connected, it includes not only cases where the films, regions, and components are directly connected, but also cases where other films, regions, and components are interposed between the films, regions, and components and are indirectly connected.
  • a film, region, component, etc. are electrically connected, it includes not only cases where the film, region, component, etc. are directly electrically connected, but also cases where another film, region, component, etc. is interposed and indirectly electrically connected.
  • a membrane, region, component, etc. are fluidly connected can be interpreted to mean that the membrane, region, component, etc. each form at least a portion of a flow path through which the fluid flows.
  • a component A when a component A is fluidly connected to a component B, it means that a fluid can flow from a component A to a component B or vice versa.
  • a component A and a component B are combined so that a flow path formed by a component A and a flow path formed by a component B are directly connected, it can be considered that a component A and a component B are fluidly connected.
  • a component A and a component B are connected through a component C, such as a conduit, such that a fluid can reach a component B from a component A through a flow path formed by a component C, or when a fluid can reach a component A from a component B through a flow path formed by a component C, it can be considered that a component A and a component B are fluidly connected.
  • a component C fluidly connects a component A and a component B.
  • a component A and a component B can be considered fluidly connected even when a component A and a component B are fluidly connected through a plurality of components.
  • a coolant injection system may include a cartridge for providing the coolant; a nozzle fluidly connected to the cartridge and for injecting the coolant provided from the cartridge into the target area; a heater interposed between the cartridge and the nozzle for heating the coolant transferred from the cartridge to the nozzle; and a valve interposed between the cartridge and the nozzle for allowing the coolant discharged from the cartridge to be transferred to the nozzle.
  • the heater may be placed between the valve and the cartridge so that the coolant reaches the valve after being heated.
  • the heater may be arranged so that the coolant is heated before it reaches the valve, so that heating efficiency is increased compared to heating the coolant after it reaches the valve.
  • the coolant injection system further includes a battery electrically connected to the heater to provide power to the heater, wherein the increased heating efficiency can reduce the power consumption provided to the heater from the battery.
  • the coolant injection system further includes a cartridge connecting part connecting the cartridge and the coolant injection system so that the coolant provided from the cartridge is delivered to the coolant injection system; and the heater can be interposed between the valve and the cartridge connecting part.
  • the coolant injection system further includes a controller provided to control power applied to the heater; a temperature sensor provided to sense a temperature of the target area; and a battery electrically connected to the heater to provide power to the heater; wherein the controller receives a temperature value of the target area from the temperature sensor, determines power to be applied to the heater based on the received temperature value, and controls power applied to the heater such that the determined power is applied to the heater through the battery.
  • the coolant injection system further includes a controller for controlling power applied to the heater; and a battery electrically connected to the heater to provide power to the heater; wherein the controller can control power applied to the heater such that a predetermined power is provided to the heater through the battery.
  • a coolant injection device for injecting a coolant provided from a coolant storage may include a nozzle for injecting the coolant provided from the coolant storage into the target area; a heater fluidly connected to the nozzle for heating the coolant transferred to the nozzle; and a valve fluidly connected to the nozzle for allowing the coolant to be transferred to the nozzle.
  • the heater may be positioned farther from the nozzle than the valve so that the coolant, after being heated, passes through the valve and is transported to the nozzle.
  • the heater may be positioned before the coolant passes through the valve so that heating efficiency is increased compared to when the coolant is heated after passing through the valve.
  • the coolant injection device further includes a power supply part electrically connected to the heater to provide power to the heater; and the increased heating efficiency can reduce the amount of power provided to the heater from the power supply part.
  • the coolant injection device further includes a coolant storage connecting part connecting the coolant storage and the coolant injection device so that the coolant provided from the coolant storage is delivered to the coolant injection device, and the heater can be fluidly connected between the valve and the coolant storage connecting part.
  • the coolant injection device further includes a controller for controlling power applied to the heater; a temperature sensor for sensing the temperature of the target area; and a power supply part electrically connected to the heater for providing power to the heater; and the controller can receive a temperature value of the target area from the temperature sensor, determine power to be applied to the heater based on the received temperature value, and control power applied to the heater such that the determined power is applied to the heater through the power supply part.
  • the coolant injection device further includes a controller for controlling power applied to the heater; and a power supply part electrically connected to the heater to provide power to the heater; and the controller can control power applied to the heater so that a predetermined power is provided to the heater through the power supply part.
  • a coolant injection system may include a cartridge that provides the coolant; a nozzle that is fluidly connected to the cartridge and sprays the coolant provided from the cartridge to the target area; and a heater that is interposed between the cartridge and the nozzle and heats the coolant provided from the cartridge.
  • the heater may include a body, wherein the body includes a first surface, a second surface opposite the first surface, a third surface perpendicular to the first surface and the second surface, and a fourth surface opposite the third surface, wherein the third surface is closer to the cartridge than the fourth surface, and the fourth surface is closer to the nozzle than the third surface; a first thermoelectric element attached to the first surface of the body; and a second thermoelectric element attached to the second surface of the body.
  • the body includes a plurality of flow paths forming a portion of a route through which the coolant is transferred from the cartridge to the nozzle, each of the plurality of flow paths having a cylindrical shape extending from the third surface to the fourth surface and having a diameter less than a predetermined diameter, and each of the plurality of flow paths can be arranged to be spaced apart from each other.
  • the diameter of each of the plurality of euros can be determined according to the length from the third side to the fourth side and the target heat transfer area.
  • the plurality of euros may be arranged in a row along a first axis, wherein the first axis may be perpendicular to a direction in which the plurality of euros extend and parallel to the first surface and the second surface.
  • the vertical distance between each of the plurality of euros and the first side or the second side may be less than or equal to a predetermined distance, and the predetermined distance may be less than or equal to half the distance between the first side and the second side minus half the diameter.
  • the plurality of paths may be spaced apart in a first axis direction, and the first axis may be perpendicular to a direction in which the plurality of paths extend and parallel to the first surface and the second surface.
  • each of the plurality of paths may have a diameter of 3.1 mm or less, and the sum of the heat transfer areas of the plurality of paths may be 20 mm ⁇ 2 or more.
  • each of the plurality of paths may have a diameter of 0.7 mm or less, and the sum of the heat transfer areas of the plurality of paths may be 130 mm ⁇ 2 or more.
  • half of the plurality of paths may be arranged in a row along a first axis, and the other half may be arranged in a row along a second axis that is parallel to the first axis but spaced apart from the first axis, wherein the first axis and the second axis may be perpendicular to a direction in which the plurality of paths extend and may be parallel to the first surface and the second surface.
  • a first vertical distance between the plurality of euros of the half and the first side and a second vertical distance between the plurality of euros of the other half and the second side are equal, and the first vertical distance and the second vertical distance may be less than or equal to a predetermined distance.
  • each of the plurality of euros may have a diameter of 0.5 mm or less.
  • the plurality of paths may be arranged in a row along a first axis, wherein the first axis is perpendicular to a direction in which the plurality of paths extend, parallel to the first surface and the second surface, and may pass through a center between the first surface and the second surface.
  • the number of said plurality of euros may be 17 or less.
  • each of the plurality of euros can extend with a constant diameter from the third surface to the fourth surface.
  • a coolant injection system for injecting a coolant may include a cartridge for providing the coolant; a nozzle fluidly connected to the cartridge and for injecting the coolant provided from the cartridge to the target area; and a heater interposed between the cartridge and the nozzle and for heating the coolant provided from the cartridge.
  • the heater is a body that provides a space where the coolant is heated.
  • the body forms at least a portion of a route through which the coolant flows and includes a flow path extending from one end of the body to the other end of the body; and may include a first thermoelectric element and a second thermoelectric element arranged on a first portion of an outer surface of the body and configured to provide heat to the coolant through the body.
  • the heater comprises: a first sealing member disposed within one end of the body to prevent a coolant flowing into the body from the cartridge from leaking out of the root; a second sealing member disposed within the other end of the body to prevent a coolant flowing out of the body from the nozzle from leaking out of the root; a first insulating member disposed to physically contact an outer surface of the first sealing member and surround a second portion of the outer surface of the body to prevent heat provided through the first and second thermoelectric elements from being transferred through the outer surface of the body; wherein the second portion is different from the first portion and is closer to one end of the body than the first portion; And a second insulating member that is arranged to surround at least a third portion of the outer surface of the body so as to physically contact the outer surface of the second sealing member and prevent heat provided through the first and second thermoelectric elements from being transferred through the outer surface of the body; wherein the third portion is different from the first portion and the second portion, and is closer to the other end of the body than the first portion;
  • the first sealing member protrudes toward the cartridge more than the first insulating member
  • the second sealing member protrudes toward the nozzle more than the second insulating member
  • the length variability of the first sealing member and the second sealing member may be greater than the length variability of the first insulating member and the second insulating member.
  • it may further include a valve fluidly connected between the heater and the cartridge, allowing a coolant provided from the cartridge to be transferred to a flow path of the heater; a valve connection surrounding at least a portion of the heater and fluidly connecting the valve and the heater; and a nozzle connection surrounding at least a portion of the heater and fluidly connecting the nozzle and the heater.
  • the length of the first sealing member and the second sealing member in the direction of the central axis can be reduced while the valve connection part and the nozzle connection part are pressurized to be coupled.
  • first sealing member and the second sealing member may be deformed in shape to spread in the flow direction.
  • valve connection portion may be pressurized until a surface of the valve connection portion that is in physical contact with the first sealing member physically contacts the first insulating member
  • nozzle connection portion may be pressurized until a surface of the nozzle connection portion that is in physical contact with the second sealing member physically contacts the second insulating member, so that the valve connection portion and the nozzle connection portion may be joined.
  • first insulating member may be in physical contact with an outer surface of the first sealing member so that the first sealing member is not damaged by a pushing force generated while the coolant flows through the route
  • second insulating member may be in physical contact with an outer surface of the first sealing member so that the second sealing member is not damaged by a pushing force generated while the coolant flows through the route
  • first sealing member and the second sealing member may be rubber, and the first insulating member and the second insulating member may be Teflon.
  • first sealing member and the second sealing member may be an O-ring or an angle ring.
  • a coolant injection system for injecting a coolant comprises: a cartridge for providing the coolant; a nozzle fluidly connected to the cartridge and for injecting the coolant provided from the cartridge into the target area; a heater interposed between the cartridge and the nozzle for heating the coolant provided from the cartridge; a valve fluidly connected between the heater and the cartridge to allow the coolant provided from the cartridge to be transferred to a flow path of the heater; a valve connection part surrounding at least a portion of the heater and fluidly connecting the valve and the heater; and a nozzle connection part surrounding at least a portion of the heater and fluidly connecting the nozzle and the heater; wherein the heater comprises: a body providing a space in which the coolant is heated, wherein the body forms at least a portion of a route through which the coolant flows and includes a flow path extending from one end of the body to the other end of the body; It may include a first thermoelectric element and a second thermoelectric element, which are arranged on a first portion of
  • the heater further includes a first sealing member arranged within one end of the body to prevent a coolant flowing into the body from the cartridge from leaking out of the route; and a second sealing member arranged within the other end of the body to prevent a coolant flowing out of the body from the nozzle from leaking out of the route; and in response to the valve connection and the nozzle connection being pressurized and coupled, there is an air gap between one end of the body and the valve connection and between the other end of the body and the nozzle connection.
  • the air gap may be for insulation between one end of the body and the valve connection and between the other end of the body and the nozzle connection.
  • the first sealing member protrudes further toward the cartridge than one end of the body and physically contacts one surface of the valve
  • the second sealing member protrudes further toward the nozzle than the other end of the body and physically contacts one surface of the nozzle connection
  • the width and width of the internal space created by combining the valve connection and the nozzle connection may be longer than the width and width of one end of the body and the other end of the body.
  • the length of the first sealing member and the second sealing member in the direction of the central axis of the body can be reduced.
  • first sealing member and the second sealing member may be deformed in shape to spread in the flow direction.
  • first sealing member and the second sealing member may be made of rubber and may be an O-ring or an angle ring.
  • ‘Target’ may mean a body part of a person or animal on which a cosmetic or medical effect is desired to be produced by spraying a coolant.
  • a ‘target area’ may include a target area, which may include a region of a body surface (e.g., skin) of a human or animal, where the sprayed coolant reaches and cools, at a point in time when the coolant is sprayed to produce a cosmetic or medical effect on the body part.
  • a target area may include a region of a body surface (e.g., skin) of a human or animal, where the sprayed coolant reaches and cools, at a point in time when the coolant is sprayed to produce a cosmetic or medical effect on the body part.
  • the target is a specific part of the skin of a human or animal, such as a dot, an injection site, a whitening effect expression site, etc., on which a cosmetic effect or medical effect is desired, and the target area includes the specific part that is the target, and when a coolant is sprayed on the specific part, it is described as a part of the skin where the coolant reaches and cools among the entire skin, but the technical idea of the present disclosure is not limited thereto.
  • the ‘surface temperature’ of the target area may mean a temperature measured for the surface of the target area using a temperature sensor.
  • the surface temperature of the target area may mean a temperature measured for a temperature sensing area that at least partially overlaps the target area.
  • coolant may refer to a substance capable of applying cooling energy to a target area.
  • carbon dioxide CO2
  • liquid nitrogen LN
  • oxygen O2
  • nitrous oxide N2O
  • nitrogen monoxide NO
  • hydrofluorocarbon HFC series substances
  • methane CH4
  • PFC SF6, krypton, helium-3
  • ethyl chloride dimethyl ether
  • chlorofluoromethane chloromethane
  • propane, butane coolant
  • coolant cooling gas, air, or a combination thereof
  • composition is a concept that encompasses not only pharmaceutical compositions used for medical treatment purposes but also cosmetic compositions used for cosmetic purposes, and may mean a substance containing an effective ingredient that induces or generates a medical effect and/or cosmetic effect.
  • the composition in the present disclosure is characterized by being delivered to a skin layer (e.g., transdermally), the composition may mean a substance that produces a cosmetic effect or a medical effect when delivered to the skin layer.
  • the composition may contain Vitamin C, Niacinamide, Soluble Licorice Extract, Arbutin, Hyaluronic Acid, Potassium Hyaluronate, Hydrolyzed Hyaluronic Acid, Hydrolyzed Sodium Hyaluronate, Hydroxypropyltrimonium Hyaluronate, Sodium Acetylated Hyaluronate, Sodium Hyaluronate Crosspolymer, Sodium Hyaluronate, Retinol, Retinyl palmitate, It can be adenosine, peptide, coenzyme Q10, adult stem cell, antioxidant, lidocaine, botulinum toxin, exosome, or a combination of these.
  • the composition may further include base components such as purified water, glycerin, butylene glycol, propanediol, and silicone oil; formulation forming components such as emulsifiers, surfactants, and viscosity modifiers; and preservative components such as parabens, phenoxyethanol, benzoic acid, triclosan, benzyl alcohol, methylisothiazolinone, and 1,2-hexanediol.
  • base components such as purified water, glycerin, butylene glycol, propanediol, and silicone oil
  • formulation forming components such as emulsifiers, surfactants, and viscosity modifiers
  • preservative components such as parabens, phenoxyethanol, benzoic acid, triclosan, benzyl alcohol, methylisothiazolinone, and 1,2-hexanediol.
  • FIG. 1 and FIG. 2 are drawings showing a coolant injection system (100) according to the present disclosure.
  • the coolant injection system (100) may include a coolant injection device (1000) and a coolant storage (Coolant Storage; 2000).
  • the coolant injection device (1000) may be designed to receive a coolant and inject the coolant. Specifically, as shown in FIGS. 1 and 2, a coolant storage (2000) in which the coolant is stored is coupled to the coolant injection device (1000), and the coolant stored in the coolant storage (2000) may be injected to the outside through the coolant injection device (1000).
  • the configurations of the coolant injection device (1000) will be specifically described in FIG. 3.
  • the coolant injection device (1000) can control the flow rate and temperature of the supplied coolant. Specifically, the coolant injection device (1000) can control the injection amount, injection time, temperature, and/or pressure of the coolant.
  • the pressure within the coolant storage (2000) may vary depending on the temperature of the coolant storage (2000). For example, if the coolant storage (2000) is stored at a relatively high temperature, the temperature of the coolant storage (2000) may increase, and accordingly, the pressure within the coolant storage (2000) may also increase.
  • the pressure inside the coolant storage (2000) affects the pressure before the coolant is injected from the coolant injection device (1000), and accordingly, affects the temperature change due to expansion when the coolant is injected from the coolant injection device (1000).
  • the higher the pressure inside the coolant storage (2000) the higher the pressure of the coolant inside the coolant injection device (1000), and as the pressure difference between the pressure of the coolant and the external pressure (e.g., atmospheric pressure) of the coolant injection device (1000) increases, the injection speed of the coolant increases.
  • the coolant expands and at least a portion of the coolant vaporizes. At this time, energy required for the vaporization of the coolant is used, and according to the law of conservation of energy, the temperature of the coolant injected from the coolant injection device (1000) can be lowered.
  • the coolant storage (2000) may be a cartridge.
  • the cartridge is a container designed to safely and efficiently store and transport a coolant, and is a highly portable container.
  • a coolant injection device 1000
  • the cartridge can store the coolant under a certain pressure, and the pressure can be determined between about 35 bar and 1000 bar at 0 to 40° C., for example, between about 35 bar and 100 bar.
  • FIG. 3 illustrates the components and their connection relationships included in a coolant injection device (1000) applicable to embodiments of the present disclosure.
  • the coolant injection device (1000) applicable to embodiments of the present disclosure does not include only the components described in FIG. 3, and additional components other than the components described in FIG. 3 may be included as needed.
  • the coolant injection device (1000) does not necessarily have to include the components described in FIG. 3, and a coolant injection device (1000) with some components omitted may be implemented as needed.
  • a coolant injection device (1000) applicable to embodiments of the present disclosure may include a flow controller (1100), a temperature controller (1200), an injection unit (1300), a controller (1400), a power supply (1500), a temperature sensor (1600), and an I/O interface (1700).
  • the I/O interface (1700) may include an input unit (1710) and an output unit (1720).
  • the flow controller (1100), the temperature controller (1200) and the injection unit (1300) are fluidly connected to the coolant storage (2000) to form at least a part of a transfer route. That is, the flow controller (1100), the temperature controller (1200) and the injection unit (1300) are also fluidly connected to each other.
  • the transfer route means a way along which the coolant is transferred until the coolant is discharged from the coolant storage (2000) and injected out of the injection unit (1300).
  • the flow controller (1100), the temperature controller (1200), and the injector (1300) may be fluidly connected to each other via a conduit.
  • the flow controller (1100), the temperature controller (1200), and the injector (1300) may form a transport route through which the coolant is transported together with at least one conduit.
  • the flow controller (1100) is a device that controls the flow of coolant and can allow the coolant to be transported to the injection unit (1300) through the transport route.
  • the flow controller (1100) can be a valve. When the valve is open, the coolant can be transported from the valve toward the injection unit (1300), and when the valve is closed, the coolant that does not pass through the valve cannot be transported toward the injection unit (1300).
  • the amount of cooling energy per unit time provided to the target area can be controlled using a flow controller (1100). For example, if the opening and closing cycle of the valve is controlled, the amount of coolant sprayed per unit time to the target area can be controlled.
  • valve may be a solenoid valve, but is not limited thereto. That is, any valve capable of controlling the flow rate of the coolant may be used as the flow controller (1100) according to the present disclosure.
  • the flow controller (1100) may be referred to as a valve.
  • the injection unit (1300) may include a structure for injecting a coolant. Specifically, the injection unit (1300) may extend from one end to the other to form a path, which is a part of a transport route, and may include a portion where the width of the path is relatively narrow.
  • the coolant passing through the injection unit (1300) may have its pressure increased as it passes through the narrow portion, and may rapidly cool its temperature as it expands due to the pressure drop while being injected at atmospheric pressure, and may also be injected at a high speed. At this time, the coolant may have a very low temperature, and as mentioned above, the temperature controller (1200) controls the temperature to prevent overcooling due to this.
  • the injection unit (1300) may be referred to as a nozzle.
  • the technical idea of the present disclosure is not limited thereto, and the injection unit (1300) may be understood as a configuration including a path for injecting coolant to the outside of the coolant injection device (1000).
  • the injector (1300) can be attached to and detached from the coolant injector (1000).
  • the injector (1300) can be attached to or detached from the coolant injector (1000) through an injector coupling portion (not shown).
  • the coolant injector (1300) can be physically connected to and integrally configured with the coolant injector (1000).
  • the temperature sensor (1600) can obtain temperature information by measuring the temperature of the target area where the coolant is sprayed. In addition, the temperature sensor (1600) can provide the obtained temperature information to the control unit (1400). Meanwhile, the temperature sensor (1600) included in the coolant spraying device (1000) can be one or more. For example, one temperature sensor can measure the temperature of the target area and provide the obtained temperature information to the controller (1400), or two or more temperature sensors can each measure the temperature of the target area and provide the obtained temperature information to the controller (1400).
  • the I/O interface may include an input section (1710) and an output section (1720).
  • the input unit (1710) may be called an input interface because it provides an interface, such as a switch, to receive user input.
  • the input unit (1710) can receive a user's input.
  • the input unit (1710) includes at least one push button switch and can provide a push input signal to the control unit (1400) according to the user's pressing of the push button switch.
  • the input unit (1710) includes at least one rotary switch and can provide a rotary input signal according to the user's manipulation of the rotary switch to the control unit (1400).
  • the rotary input signal can be used to set a target temperature and/or a target time, etc.
  • the target temperature can mean a temperature at which a target or a target area to which a coolant is to be sprayed is to be cooled.
  • the target time can mean a time during which the coolant spraying should be maintained or a time during which the surface temperature of the target area reaches the target temperature.
  • the output unit (1720) may be referred to as an output interface since it provides an interface for outputting various information for using the coolant injection device (1000) to the user.
  • the output unit (1720) includes a display, and various information for setting a target temperature, a target time, etc. may be output through the display, and during operation of the coolant injection device (1000), information such as the real-time temperature of a target area measured by the sensor unit (1600) or the total time for which the coolant has been injected may be output.
  • the controller (1400) can be electrically connected to the flow controller (1100), the temperature controller (1200), the temperature sensor (1600), the I/O interface (1700), and the power supply (1500).
  • the controller (1400) can control a configuration electrically connected to the controller (1400). For example, the controller (1400) can set a target temperature or a target time, etc. based on a rotation input signal received from the input unit (1710). When a push input signal is received, the controller (1400) can control the opening and closing of the flow controller (1100) based on the set target temperature or target time.
  • the controller (1400) may control the temperature controller (1200) to control the temperature of the coolant.
  • the controller (1400) may supply power to the temperature controller (1200) so that heat energy for heating the coolant may be generated in the temperature controller (1200).
  • the controller (1400) may control the power supplied to the temperature controller (1200) by transmitting the voltage provided by the power supply (1500) to the temperature controller (1200) in a PWM (Pulse Width Modulation) manner. Specifically, when the power supplied to the temperature controller (1200) increases, the heat energy generated in the temperature controller (1200) may increase.
  • PWM Pulse Width Modulation
  • the controller (1400) can control the temperature controller (1200) based on temperature information received from the temperature sensor (1600) and the set target temperature.
  • the controller (1400) can set a target temperature and/or a target time.
  • the controller (1400) can provide various information for inducing the user to set a target temperature and/or a target time through the output unit (1720), receive a setting input signal according to the user's operation through the input unit (1710), and set the target temperature and/or the target time based on the received setting input signal.
  • the controller (1400) can output a message to the user through the output unit (1720) indicating that operation preparation is complete, receive a switch on input signal according to the user's operation through the input unit (1710), and spray a coolant based on the received switch on input signal.
  • the controller (1400) can obtain temperature information by measuring the temperature of the target area where the coolant is sprayed through the temperature sensor (1600), compare the obtained temperature information with the set target temperature, and control power so that the determined power is applied to the temperature controller (1200). At this time, the controller (1400) can control power applied to the temperature controller (1200) to increase the thermal energy applied to the coolant through the temperature controller (1200) if the obtained temperature information is lower than the target temperature, and can control power applied to the temperature controller (1200) to decrease the thermal energy applied to the coolant through the temperature controller (1200) if the obtained temperature information is higher than the target temperature.
  • the operation of the controller (1400) is not limited to the above-described embodiment.
  • the controller (1400) may apply a predetermined power to the temperature controller (1200) so that a certain amount of thermal energy is continuously provided to the coolant without monitoring the temperature of the target area. Accordingly, the temperature of the coolant can be controlled within a certain range. In this case, the step of setting or receiving the target temperature may be omitted.
  • the power supply (1500) is a device that supplies power to the controller (1400).
  • the power supply (1500) can also supply power to the flow controller (1100), the temperature controller (1200), the temperature sensor (1600), and the I/O interface (1700) through the controller (1400).
  • the power supply (1500) can be indirectly electrically connected to the flow controller (1100), the temperature controller (1200), the temperature sensor (1600), and the I/O interface (1700) through the controller (1400).
  • the power supply (1500) may be a battery that applies a constant voltage. If the coolant injection system (100) is implemented to increase the continuity of use of the coolant injection device (1000) as in FIG. 2, the power supply (1500) may be a configuration that includes a transformer that converts an externally supplied voltage and transmits it to the coolant injection device (1000) and/or a rectifier that converts an AC voltage into a DC voltage.
  • the present invention is not limited thereto, and even if the coolant injection system (100) is implemented to increase the continuity of use of the coolant injection device (1000) as in FIG. 2, the power supply (1500) may be implemented as a battery in order to further increase the convenience of use.
  • the coolant injection device (1000) may further include a composition providing unit.
  • the composition providing unit may be configured to be detachably attached to the coolant injection device (1000) or may be configured as an integral part with the coolant injection device (10000).
  • the composition providing unit is a device that stores and sprays a composition, and the composition sprayed by the composition providing unit meets a coolant sprayed from the spraying unit (1300), and the composition can be transferred to a target area (e.g., a skin layer) by kinetic energy obtained by colliding with the coolant sprayed from the spraying unit (1300).
  • the composition can also be frozen by cooling energy transferred from the coolant as it collides with the coolant.
  • the coolant when the composition is delivered to the target area by collision with a coolant, the coolant may be a cooling medium that cools the target area and a delivery medium for delivering the composition to the target area.
  • the coolant injection device (1000) may further include a memory.
  • the memory may store various data, programs, or applications necessary for the operation of the coolant injection device (1000).
  • the program or application stored in the memory may include one or more commands.
  • the various data may include information obtained from the temperature sensor (1600), the temperature of the temperature controller (1200), and voltage, current, or power values applied to the temperature controller (1200).
  • the program stored in the memory may include commands corresponding to a plurality of control methods for controlling the temperature controller (1200) described below.
  • the memory may temporarily or semi-permanently store various data. Examples of the memory may include a hard disk drive (HDD), a solid state drive (SSD), a flash memory, a read-only memory (ROM), a random access memory (RAM), etc.
  • HDD hard disk drive
  • SSD solid state drive
  • flash memory a read-only memory
  • RAM random access memory
  • the coolant injection device (1000) may include a communication unit for communicating with an external device.
  • the communication unit may perform wired or wireless communication, and may be, for example, a wired/wireless LAN (Local Area Network) module, a WAN (Wide area network) module, an Ethernet module, a Bluetooth module, a Zigbee module, a USB (Universal Serial Bus) module, an IEEE 1394 module, a Wi-Fi module, a mobile communication module, a satellite communication module, or a combination thereof, but is not limited thereto.
  • FIGs 4 and 5 illustrate a temperature controller (1200) used in a coolant injection device (1000).
  • the temperature controller (1200) may form a part of a transport route through which the coolant is transported as described above. That is, the temperature controller (1200) is configured to generate thermal energy to control the temperature of the coolant by being placed on a transport route through which the coolant is transported within the coolant injection device (1000).
  • the temperature controller (1200) includes a body (1210), a thermoelectric element (1220), an insulating member (1230), and a heat transfer medium (1240).
  • the body (1210) includes a fluid pathway (1250) that is a space in which a coolant is transported therein.
  • the fluid pathway formed inside the body (1210) may form a part of a transport route for the coolant to be discharged from a coolant storage and sprayed into the spray unit (1300) when the body (1210) is mounted in a coolant injection device (1000).
  • the body (1210) may have one end and the other end based on the direction of the central axis of the body (1210).
  • the body (1210) may have an outer surface, which is the entire surface surrounding the body (1210) with the central axis as the center.
  • the outer surface of the body (1210) means the entire surface surrounding the body (1210) centered on the central axis, and it should be understood that the outer surface of the body (1210) is formed by one surface or by a plurality of surfaces.
  • the body (1210) may also be referred to as a block.
  • the block is not limited to having a specific shape, such as a square or hexahedral shape, and may have a shape including a cylinder or at least one curved surface.
  • the block should be interpreted as a component made of a solid material having an outer surface that can be combined with other components.
  • thermoelectric element (1220) is disposed on the outer side of the body (1210).
  • the meaning of the thermoelectric element (1220) being disposed on the outer side of the body (1210) may mean that the thermoelectric element (1220) is directly attached to the outer surface of the body (1210) or that the thermoelectric element (1220) is disposed so that heat generated in the thermoelectric element (1220) can be transferred to the body (1210) through a highly thermally conductive medium interposed between the thermoelectric element (1220) and the outer surface of the body (1210).
  • the thermoelectric element (1220) is an element for transferring heat energy to the coolant flowing through the passage (1250) through the outer surface of the body (1210) to heat the coolant. For example, when the controller (1400) applies power to the thermoelectric element (1220), the thermoelectric element (1220) generates heat. The heat generated in the thermoelectric element (1220) is transferred to the body (1210) to heat the coolant flowing through the passage (1250).
  • thermoelectric elements (1220) may be arranged on a first portion, which is a part of the outer surface of the body (1210).
  • first thermoelectric element and the second thermoelectric element may be arranged to face each other on the first portion, which is a part of the outer surface of the body (1210).
  • thermoelectric elements (1220) it is not necessary to use two thermoelectric elements (1220). If sufficient heat can be transferred to the coolant flowing in the flow path (1250), only one thermoelectric element (1220) may be placed on the outer surface of the body (1210). In addition, three or more thermoelectric elements (1220) may be placed on the outer surface of the body (1210) in order to quickly transfer a large amount of heat to the coolant flowing in the flow path (1250).
  • thermoelectric element (1220) may be a Peltier element or a Joule heating element, but is not limited thereto, and any element that can receive power and generate heat for heating a coolant may be used as the thermoelectric element (1220).
  • the insulating member (1230) can prevent heat transferred to the body (1210) through the thermoelectric element (1220) from being transferred to other components of the coolant injection device (1000) through at least a portion of the outer surface of the body (1210).
  • the insulation member (1230) can prevent heat from being transferred to a configuration for combining a temperature controller (1200) and a flow controller (1100) and/or a configuration for combining a temperature controller (1200) and an injection unit (1300).
  • the insulation member (1230) prevents heat from being transferred means that heat loss caused by heat transferred to the body (1210) being transferred to other components can be reduced, but does not mean that heat transferred to the body (1210) is completely blocked from being transferred to other components.
  • the insulation member (1230) By enabling the insulation member (1230) to reduce heat loss, the heat transfer efficiency of the coolant can be increased, and damage to the coolant injection device (1000) that may occur due to excessive heat transfer to other components can be prevented.
  • the insulating member (1230) is arranged at one end and the other end of the body (1210) and is arranged to surround at least a portion of the outer surface of the body (1210).
  • the first insulating member may be arranged to surround one end of the body (1210) and a second portion, which is a portion of the outer surface of the body (1210).
  • the second portion may be different from the first portion where the thermoelectric element (1220) is arranged and may not overlap.
  • the second portion may be closer to one end of the body (1210) than the first portion.
  • the end of the second portion may meet one end of the body (1210) to form a corner of the body (1210).
  • the second insulating member may be arranged to surround the other end of the body (1210) and a third portion that is part of the outer surface of the body (1210).
  • the third portion may be different from and may not overlap the first portion where the thermoelectric element (1220) is arranged and the second portion where the first insulating member is arranged.
  • the third portion may be closer to the other end of the body (1210) than the first portion.
  • an end of the third portion may meet the other end of the body (1210) to form a corner of the body (1210).
  • one end and the other end of the body (1210) are both ends of the body (1210) that intersect the central axis of the body (1210) and/or the flow path (1250) within the body (1210).
  • one end of the body (1210) may be the end where the coolant flows into the passage (1250) within the body (1210), and the other end of the body (1210) may be the end where the coolant flows out into the passage (1250) within the body (1210).
  • the temperature controller (1200) may have a first thermoelectric element and a second thermoelectric element arranged on the outer surface of the body (1210), and the first thermoelectric element and the second thermoelectric element may be arranged parallel to the central axis of the body (1210) so that sufficient heat can be applied to a coolant flowing in a flow path (1250) formed along the central axis of the body (1210).
  • the first thermoelectric element and the second thermoelectric element may be arranged to face each other with respect to the central axis of the body (1210) so that heat can be applied as evenly as possible to a coolant flowing in the flow path (1250).
  • the first insulating member can cover one end of the body (1210) and the outer surface of the body (1210) that meets one end to prevent the coolant flowing in from one end of the body (1210) from leaking out of the flow path (1250). Meanwhile, as mentioned above, the first insulating member that covers one end of the body (1210) and the outer surface of the body (1210) that meets one end can prevent heat from being transferred out of the outer surface of the body (1210) that meets one end of the body (1210).
  • the second insulating member can cover the other end of the body (1210) and the outer surface of the body (1210) that meets the other end to prevent the coolant flowing out in the other end direction of the body (1210) from flowing out outside the path (1250). Meanwhile, as mentioned above, the second insulating member that covers the other end of the body (1210) and the outer surface of the body (1210) that meets the other end can prevent heat from being transferred to the other end of the body (1210) and the outer surface of the body (1210) that meets the other end.
  • the insulation member (1230) may cover one end and a part of the other end of the body (1210) to prevent the coolant flowing from one end of the body (1210) to the other end from leaking out of the transport route.
  • the insulation member (1230) has a hole with a constant width or diameter centered on the central axis so as not to cover an area corresponding to the flow path (1250), and this hole allows the flow path (1250) to become at least a part of the transport route.
  • the first insulating member may cover at least a portion of one end of the body (1210) except for an area corresponding to the flow path (1250), and the second insulating member may cover at least a portion of the other end of the body (1210) except for an area corresponding to the flow path (1250).
  • the first insulating member may seal to prevent a coolant flowing into the body (1210) from leaking out outside the transport route
  • the second insulating member may seal to prevent a coolant flowing into the body (1210) from leaking out outside the transport route.
  • the insulating member (1230) should be understood as an element that performs both insulation and sealing. Meanwhile, the insulating member (1230) is manufactured from a material having low thermal conductivity to enhance insulation performance.
  • the insulating member (1230) may be made of a polymer-based organic material.
  • the insulating member (1230) may be made of Buna-N, fluorosilicone, Viton, EPDM (Ethylene Propylene Diene Monomer), or Teflon.
  • the first insulating member and the second insulating member may be configured to surround the first portion where the thermoelectric element (1220) is arranged. At this time, the first insulating member and the second insulating member may be configured not to be in close contact with the thermoelectric element (1220) so that the heat generated from the thermoelectric element (1220) is insulated from the outside.
  • a heat transfer medium (1240) is included inside the flow path (1250) to increase the efficiency of heat transfer to the coolant.
  • the heat transfer medium (1240) increases the thermal contact area between the heat generated from the thermoelectric element (1220) and the coolant, thereby allowing heat to be applied to the coolant passing through the flow path (1250) as quickly as possible.
  • the heat contact area is widened, so the heat transfer efficiency can be increased.
  • the size of the coolant injection device (1000) itself must eventually be increased. Since the convenience of use is reduced when the coolant injection device (1000) is increased beyond a certain size, the size of the coolant injection device (1000) cannot be increased indefinitely in order to increase the heat contact area.
  • a heat transfer medium (1240) may be included in the flow path (1250) of the temperature controller (1200).
  • the heat transfer medium (1240) enables the thermal contact area of the coolant to increase. This allows heat to be transferred to the coolant quickly, allowing the temperature of the coolant to be controlled rapidly, thereby enabling precise temperature control of the coolant injection device (1000).
  • the heat transfer medium (1240) is generated through a sintering process.
  • the heat transfer medium (1240) generated through the sintering process has a porous structure.
  • the heat generated from the thermoelectric element (1220) is transferred to the heat transfer medium (1240) through the body (1210).
  • the coolant is heated by contacting the heat transferred to the heat transfer medium (1240) while passing through the porous structure.
  • the heat transfer medium (1240) having a porous structure generated through the sintering process is referred to as a porous sintered structure heat transfer medium.
  • Example 1 Temperature controller without porous sintered structure heat transfer medium
  • the porous sintered structure heat transfer medium is created through a sintering process.
  • precise work is required.
  • the sintering process must be performed to have a uniform porous structure, which is a task that requires considerable difficulty.
  • FIG. 6 shows the configuration of a body (1210) of a temperature controller (1200) having a heat transfer efficiency equivalent to that of a heat transfer medium having a porous sintered structure without including a porous sintered structure heat transfer medium.
  • the body (1210) of the temperature controller (1200) has a first surface (1210a) and a second surface (1210b) facing the first surface (1210a) with respect to the central axis.
  • the first surface (1210a) and the second surface (1210b) are included in the outer surface of the body (1210) defined above.
  • the body (1210) has one end and the other end intersecting the central axis of the body (1210). At this time, one end of the body (1210) is formed where the coolant flows into the body (1210), and when mounted in the coolant injection device (1000), it is closer to the coolant storage (2000) than the other end of the body (1210).
  • One end of the body (1210) may be referred to as a third surface (1210c).
  • the other end of the body (1210) is formed where the coolant flows out from the body (1210), and when mounted in the coolant injection device (1000), is closer to the injection portion (1300) than one end of the body (1210).
  • the other end of the body (1210) may be referred to as a fourth surface (1210d).
  • each path (1250) may be formed inside the body (1210) according to the present embodiment.
  • Each path (1250) extends from the third surface (1210c) to the fourth surface (1210d). In other words, each path (1250) may penetrate the body (1210) in the direction of the central axis.
  • each of the euros (1250) may have a cylindrical shape.
  • each of the euros (1250) does not necessarily have to have a cylindrical shape, and therefore, the shape of the euros (1250) is not limited to a cylindrical shape.
  • each of the channels (1250) has a shape other than a cylindrical shape (for example, a through shape having one or more angles, such as a rectangular parallelepiped)
  • the coolant may collide with the angled corners of the channels as it moves through the channels. If the coolant collides with the angled corners, the heat transfer efficiency may be reduced due to pressure loss or pressure change due to pressure expansion/reduction, and therefore, a cylindrical shape may be the most advantageous in terms of heat transfer efficiency.
  • the diameter of the transport route from the coolant storage connection connecting the coolant storage (2000) and the coolant injection device (1000) to the temperature controller (1200) may be wider than the diameter of each of the flow paths (1250).
  • each of the channels (1250) may extend with a constant diameter from the third surface (1210c) to the fourth surface (1210d). If each of the channels (1250) extends with a gradually decreasing diameter from the third surface (1210c) to the fourth surface (1210d) or extends with a gradually increasing diameter, the cross-sectional area of the channels (1250) through which the coolant passes may continuously change, causing a pressure loss, which may cause the coolant to expand unintentionally. In this case, the speed and temperature of the coolant may be affected, which may reduce the heat transfer efficiency of the coolant. Therefore, it may be desirable for each of the channels (1250) to always be formed with a constant diameter.
  • each of the euros (1250) must be physically separated from each other within the body (1210). At this time, the distance between the euros (1250) may be constant, but may not be constant.
  • the heat transfer efficiency is calculated as (heat transfer coefficient x total cross-sectional area of the flow paths). At this time, the heat transfer coefficient increases as the diameter of the flow path (1250) decreases. On the other hand, as the number of flow paths increases, the total cross-sectional area of the flow paths increases, so the heat transfer efficiency increases. Therefore, assuming that the length of the flow path (i.e., the length from the third side (1210c) to the fourth side (1210d) of the body (1210)) is the same, the heat transfer efficiency increases as the diameter of the flow path (1250) decreases and the number of flow paths (1250) included inside the body (1210) increases.
  • a coolant injection device (1000) using a temperature controller having a porous sintered structure heat transfer medium takes 2.5 seconds to reach the temperature of a target area to the target temperature of 5 degrees, and at this time, the PWM duty ratio of the voltage applied to the thermoelectric element (1220) is 25%.
  • the sum of the heat transfer areas of the passages (1250) must be at least 130 mm ⁇ 2.
  • the length of the body (1210) is 13.6 mm, in order for the sum of the heat transfer areas to be at least 130 mm ⁇ 2, the number of channels included inside the body (1210) varies depending on the diameter of the channels (1250).
  • the number of euros (1250) is 3
  • the diameter of the euro (1250) is 0.5 mm
  • the number of euros (1250) is 6
  • the diameter of the euro (1250) is 0.3 mm
  • the number of euros is 17.
  • the diameter of the euro (1250) is 3.1 mm
  • the number of euros (1250) can be 1. That is, the diameter of the euro (1250) can be 3.1 mm or less.
  • the temperature controller (1200) according to the present embodiment can have a heat transfer efficiency equivalent to that of a porous sintered structure heat transfer medium, as described below.
  • a temperature controller (1200) having a diameter of 0.5 mm and 6 channels can have a higher heat transfer efficiency than a porous sintered structure heat transfer medium.
  • a temperature controller (1200) having a diameter of 0.3 mm and 17 channels can have a higher heat transfer efficiency than a temperature controller (1200) having a diameter of 0.5 mm and 6 channels.
  • the temperature controller (1200) according to Example 1 does not have a heat transfer efficiency equivalent to that of the temperature controller having the porous sintered structure heat transfer medium described above, if the sum of the heat transfer areas of the passages (1250) is 20 mm ⁇ 2 or more, it can have a heat transfer efficiency that can substantially increase the temperature of the coolant. Accordingly, when designing the temperature controller (1200) according to Example 1, it can be designed so that the sum of the heat transfer areas of the passages (1250) is 20 mm ⁇ 2 or more, and even in this case, the diameter of the passages (1250) can be 3.1 mm or less as described above.
  • FIGS. 7 and 8 examples in which a plurality of flow paths (1250) are spaced apart and arranged inside a body (1210) will be examined through FIGS. 7 and 8. However, it should not be interpreted as being limited to the plurality of flow paths (1250) being arranged inside a body (1210) as described in FIGS. 7 and 8, and if it is an arrangement method to which the principles of the examples described below are applied, it should be understood as an arrangement method of flow paths that can be inferred according to the present disclosure.
  • Fig. 7(a) shows an example of arranging three filaments (1250) inside a body (1210)
  • Fig. 7(b) shows an example of arranging six filaments (1250) inside a body (1210).
  • a first thermoelectric element (1220a) is arranged on the first surface (1210a)
  • a second thermoelectric element (1220b) is arranged on the second surface (1210b).
  • the meaning of arranging a thermoelectric element (1220) has already been explained in [Configuration of Temperature Controller (1200)], so a detailed description thereof will be omitted.
  • thermoelectric element (1220) and the flow path (1250) become closer, the heat transfer distance between the thermoelectric element (1220) and the flow path (1250) becomes shorter, thereby increasing the heat transfer efficiency.
  • a plurality of paths (1250) may be arranged in a row along a first axis, but may be spaced apart from each other.
  • the first axis may be an axis orthogonal to the central axis of the body (1210), and a distance from the first axis to the first thermoelectric element (1220a) and a distance from the first axis to the second thermoelectric element may be the same axis.
  • the first axis may be perpendicular to the direction in which the plurality of paths (1250) extend, and may be parallel to the first surface (1210a) and the second surface (1210b).
  • first vertical distance from the first thermoelectric element (1220a) to the outer surface of the flow path may be equal to the second vertical distance from the second thermoelectric element (1220b) to the outer surface of the flow path.
  • first vertical distance and the second vertical distance may be equal to or less than a predetermined distance.
  • first vertical distance and the second vertical distance may be equal to or less than a value obtained by subtracting half of the diameter of the flow path (1250) from half of the distance between the first surface and the second surface.
  • FIG. 7(b) shows that multiple paths (1250) are arranged in a row along the first axis and the second axis, but spaced apart from each other.
  • the first axis and the second axis may be spaced apart from each other.
  • half of the multiple paths (1250) may be arranged in a row along the first axis, and the remaining half may be arranged in a row along the second axis.
  • this is not limited thereto, and the number of paths (1250) arranged along each of the first axis and the second axis may be different.
  • the first vertical distance from the first thermoelectric element (1220a) to the outer surface of the flow path may be equal to the second vertical distance from the second thermoelectric element (1220b) to the outer surface of the flow path.
  • the first vertical distance and the second vertical distance may be less than or equal to a predetermined distance. For example, the longer the separation distance between the first axis and the second axis, the shorter the first vertical distance and the second vertical distance, so that the separation distance between the first axis and the second axis may exceed the predetermined distance.
  • the method in which the plurality of paths (1250) are arranged along one or more axes is not limited to the interpretation of FIG. 7(a) and (b).
  • the plurality of paths (1250) may be arranged along three or more rows so that the first vertical distance and the second vertical distance can be as short as possible according to the above-mentioned principle; however, when there are three or more axes, the distance between the axes may be determined by taking into account the heat transfer efficiency of paths arranged along axes other than the axis closest to the first thermoelectric element (1220a) and the axis closest to the second thermoelectric element (1200b).
  • FIGS. 8(a) and (b) show that a plurality of flow paths (1250) are not arranged in a row along one or more axes, but are arranged irregularly.
  • the smaller the diameter of each flow path (1250) and the larger the number of flow paths (1250) the higher the heat transfer efficiency. Accordingly, even if a plurality of flow paths (1250) are arranged irregularly as in FIGS. 8(a) and (b), the heat transfer efficiency can be sufficiently increased by making the diameter of each flow path (1250) smaller and increasing the number of flow paths (1250).
  • a coolant injection device (hereinafter referred to as the “comparative subject”) equipped with a heater having a heat transfer medium and a porous sintered structure applied to and sold by the conventional License Medical Company’s TargetCool was prepared.
  • the length of the body of the heater is 13.6 mm.
  • the coolant injection device was connected to the cartridge. Meanwhile, the coolant was supplied from the cartridge, passed through the valve, heater, and nozzle in sequence, and sprayed from the nozzle. In other words, the cartridge, valve, heater, and nozzle were fluidly connected in a row to form a path along which the coolant moved.
  • Example 1 of the present disclosure a coolant injection device (hereinafter, “experimental subject”) equipped with the heater according to Example 1 of the present disclosure was prepared. As shown in Fig. 7(a), three cylindrical channels were arranged in a single row on the body of the heater, and the vertical distance between the first surface of the body and the channel and the vertical distance between the second surface of the body and the channel were the same. The diameter of each channel was 0.7 mm, and the length of the body was 13.6 mm.
  • the coolant injection device was connected to the cartridge. Meanwhile, the coolant was supplied from the cartridge, passed through the valve, heater, and nozzle in sequence, and was sprayed from the nozzle. In other words, the cartridge, valve, heater, and nozzle were fluidly connected in a row to form a path for the coolant to move.
  • the coolant used was liquefied CO2 for both the control and experimental subjects.
  • the target temperature was set to 5 degrees, and spraying the coolant on the skin for more than 8 seconds was repeated 5 times in total. In other words, the action of spraying the coolant on the skin for more than 8 seconds was performed 5 times.
  • the time taken to reach the target temperature of 5 degrees was measured to evaluate the cooling efficiency, and the PWM duty ratio of the voltage applied to the heater was measured to compare the power efficiency of the heater.
  • Figure 9(a) shows data showing the results of measuring skin temperature when a coolant spray device, which is the subject of the experiment, is used
  • Figure 9(b) shows data showing the results of measuring skin temperature when a coolant spray device, which is the subject of the comparison, is used.
  • Fig. 9(c) shows the PWM duty ratio as a TEC input value when the coolant injection device, which is the subject of the experiment, is used
  • Fig. 9(d) shows the PWM duty ratio as a TEC input when the coolant injection device, which is the subject of comparison, is used.
  • the value written in the TEC input/10)% means the TEC input, which means the PWM duty ratio.
  • the TEC input which means the PWM duty ratio.
  • the value written in the TEC input is 135, it means that the TEC input and the PWM duty ratio are 13.5%.
  • the maximum values of the TEC input and the PWM duty ratio decrease from 50% to 30%, it can be seen that the amount of power provided to the heater during the same time decreases, and therefore, it should be interpreted that the smaller the maximum value of the TEC input, the less power is used to reach the target temperature.
  • both the experimental coolant injection device and the comparative coolant injection device reach the target temperature in about 2.5 seconds and maintain the target temperature thereafter.
  • the temperature control performance of the comparative coolant spray device and the experimental coolant spray device is the same as that of the experimental coolant spray device, the time it takes for the target temperature to be reached and the skin temperature is maintained at the target temperature thereafter.
  • the fact that the maximum TEC input value is the same means that the comparative coolant spray device and the experimental coolant spray device used the same power to exhibit the same temperature control performance. Using the same power means that the same amount of heat energy was transferred to the coolant through the thermoelectric element.
  • the heater according to the embodiment of the present disclosure that does not use a porous sintered structure heat transfer medium achieves the same level of heat transfer efficiency as the heater using a porous sintered structure heat transfer medium, as shown in that the same temperature control performance is achieved using the same amount of heat energy.
  • Fig. 10 shows a configuration of a coolant injection device (1000) applicable to Embodiment 2.
  • the coolant injection device (1000) may include a flow controller (1100), a temperature controller (1200), an injection unit (1300), a controller (1400), a power supply (1500), a temperature sensor (1600), and an I/O interface (1700).
  • the I/O interface (1700) may include an input unit (1710) and an output unit (1720).
  • the coolant injection device (1000) applicable to Example 2 may further include an injection unit coupling unit (1810), a flow rate regulator coupling unit (1820), and a coolant reservoir coupling unit (1830).
  • the injector coupling part (1810) is an element for coupling or separating the injector (1300) to the coolant injection device (1000).
  • the flow regulator coupling part (1820) is an element for coupling or separating the flow regulator (1100) with a specific configuration inside the coolant injection device (1000).
  • One end of the flow regulator coupling part (1820) is attached to a specific configuration of the coolant injection device (1000), and the other end of the flow regulator (1820) can be coupled with the flow regulator (1100).
  • the coolant reservoir coupling (1830) is an element for coupling or separating the coolant reservoir (2000) from the coolant injection device (100).
  • the coolant reservoir coupling (1830) may be coupled with a cartridge to couple the cartridge to the coolant injection device (1000).
  • the coolant reservoir coupling (1830) may be coupled with a hose connected to a tank to couple the tank to the coolant injection device (1000).
  • Each of the injector (1300) and the injector coupling (1810), the flow controller (1100) and the flow controller coupling (1820), and the coolant reservoir coupling (1830) and the coolant reservoir (2000) may be coupled in a rotational coupling, a press fit, a positive lock joint, or an interlocking joint manner.
  • the present invention is not limited to the above-described coupling manner, and the injector (1300) and the injector coupling (1810), the flow controller (1100) and the flow controller coupling (1820), and the coolant reservoir coupling (1830) and the coolant reservoir (2000) may be coupled in various manners.
  • a coolant reservoir coupling unit (1830), a flow controller (1100), a flow controller coupling unit (1820), a temperature controller (1200), an injection unit coupling unit (1810), and an injection unit (1300) may be fluidly connected in a series to form a transport route through which a coolant is transported. That is, each of the coolant reservoir coupling unit (1830), the flow controller (1100), the flow controller coupling unit (1820), the temperature controller (1200), the injection unit coupling unit (1810), and the injection unit (1300) may have a flow path forming a part of the transport route, and the flow paths may be fluidly connected in a series with conduits to form a transport route.
  • Fig. 10 the fluid connection is illustrated in the following order: coolant storage joint (1830), flow controller (1100), flow controller joint (1820), temperature controller (1200), injection joint (1810), and injection unit (1300), but the present invention is not limited thereto. As described below, the connection order of the components of the coolant injection device (1000) may be changed as needed.
  • the temperature controller (1200) may be placed between the injection unit coupling portion (1810) and the flow controller coupling portion (1820).
  • the temperature controller (1200) may be placed (i.e., assembled) within an internal space formed by combining the injection unit coupling portion (1810) and the flow controller coupling portion (1820).
  • Example 2 a method for efficiently assembling a temperature controller (1200) in an internal space formed by combining an injection unit coupling part (1810) and a flow controller coupling part (1820) will be examined.
  • FIG. 11 shows a process in which the temperature controller (1200) described in FIGS. 4 and 5 is assembled into the coolant injection device (1000).
  • the injection unit coupling part (1810) and the flow controller coupling part (1820) are pressed in a direction facing each other, and the pressurized injection unit coupling part (1810) and the flow controller coupling part (1820) pressurize the temperature controller (1200).
  • the pressurized temperature controller (1200) is fixed within the internal space formed by the combination of the injection unit coupling part (1810) and the flow controller coupling part (1820). In other words, the temperature controller (1200) is fixed within the internal space by the pressing force of the injection unit coupling part (1810) and the flow controller coupling part (1820) (or the flow controller (1100)).
  • the injector coupling part (1810), the flow controller coupling part (1820), and the temperature controller (1200 may not be properly assembled.
  • the length of the temperature controller (1200) is longer than the length of the internal space formed by combining the injector coupling part (1810) and the flow controller coupling part (1820), so that the injector coupling part (1810) and the flow controller coupling part (1820) may be incompletely combined or may not be combined at all.
  • the temperature controller (1200) may not be fixed to the internal space formed, and may be assembled unstably. If the injector coupling portion (1810), the flow controller coupling portion (1820), and the temperature controller (1200) are not properly assembled, the transport route through which the coolant is transported may not be properly formed, and the coolant may leak to an unintended location. Alternatively, the coolant that is not properly heated may reach the target area, thereby degrading the cooling performance and temperature control performance of the coolant injection device (1000).
  • the insulating member (1230) of the temperature controller (1200) is pressurized.
  • the insulating member (1230) is made of a hard material such as Teflon and has very little dimensional variability.
  • the temperature controller (1200) may be damaged due to the compressive stress of the insulating member (1230) made of a material with little dimensional variability.
  • a temperature controller (1200) proposed to solve the above-described problem may include a body (1210), a thermoelectric element (1220), an insulating member (1230), and a sealing member (1260).
  • the definitions of the outer surface, one end and the other end of the body (1210), the arrangement, function, and operation of the thermoelectric element (1220) are the same as those described in [Configuration of Temperature Controller (1200)], and therefore, the description is omitted.
  • the definitions and meanings of terms that are not separately defined or described in the description of the present embodiment should be interpreted as the definitions and meanings of terms described in [Configuration of Temperature Controller (1200)].
  • a path included inside the body (1210) and extending from one end of the body (1210) to the other end forms a part of the transfer route.
  • the path may include a porous sintered structure heat transfer medium (1240) as described in [Configuration of Temperature Controller (1200)].
  • the body (1210) may include a plurality of paths (1250) described in Example 1.
  • a first sealing member (1260a) is arranged in one end of the body (1210), and a second sealing member (1260b) is arranged in the other end of the body (1210).
  • the first sealing member (1260a) may include a first hole surrounding the passage (1250) or an area corresponding to the passage (1250) to prevent coolant flowing into the passage (1250) of the body (1210) from leaking out of the transport route.
  • the first sealing member (1260a) may have a shape of an O-ring or a square ring.
  • the second sealing member (1260b) may include a second hole surrounding the passage (1250) or an area corresponding to the passage (1250) to prevent the coolant flowing out of the passage (1250) of the body (1210) from flowing out outside the transport route.
  • the second sealing member (1260b) may have the shape of an O-ring or a corner ring.
  • the first part, the second part, and the third part are interpreted identically to the first part, the second part, and the third part of the [configuration of the temperature controller (1200)].
  • the first insulating member (1230a) is in physical contact with the outer surface of the first sealing member (1260a). In addition, the first insulating member (1230a) is arranged to surround the second portion. The function and role of the first insulating member are omitted as described in [Configuration of Temperature Controller (1200)].
  • the second insulating member (1230b) is in physical contact with the outer surface of the second sealing member (1260a). In addition, the second insulating member (1230b) is arranged to surround the third portion. The function and role of the second insulating member (1230b) are omitted as described in [Configuration of Temperature Controller (1200)].
  • the sealing performance of the first sealing member (1260a) and the second sealing member (1260b) can be stably maintained, and damage to the first sealing member (1260a) and the second sealing member (1260b) can be prevented.
  • hydraulic pressure may be generated in a direction that is not parallel to the central axis due to the flow rate and volume of the coolant. If the first insulating member (1230a) and the second insulating member (1230b) do not physically contact the outer surfaces of the first sealing member (1260a) and the second sealing member (1260b), respectively, the hydraulic pressure generated in a direction that is not parallel to the central axis may cause the first and second sealing members (1260a, 1260b) to move toward the outer surfaces, thereby reducing the sealing performance.
  • first and second sealing members (1260a, 1260b) are continuously exposed to hydraulic pressure in a direction that is not parallel to the central axis, fatigue may build up in the first and second sealing members (1260a, 1260b), which may eventually damage the first and second sealing members (1260a, 1260b).
  • the first insulating member (1230a) and the second insulating member (1230b) can physically contact the outer surface of the first sealing member (1260a) and the second sealing member (1260b), respectively. The insulating member physically contacting the outer surface of the sealing member prevents the sealing member from moving outward.
  • the insulating member (1230) can perform both insulation and sealing.
  • the first sealing member (1260a) and the second sealing member (1260b) can also perform both sealing and insulation.
  • the insulating member and the sealing member are referred to by different names for the convenience of explanation to distinguish the two components, and should not be interpreted as components that only perform insulation or sealing.
  • the first sealing member (1260a) protrudes toward the outside of the body (1210) in the direction of the central axis more than the first insulating member (1230a), and the second sealing member (1260b) protrudes toward the outside of the body (1210) in the direction of the central axis more than the second insulating member (1230b). That is, in the coolant injection device (1000), the first sealing member (1260a) protrudes toward the coolant storage (2000) more than the first insulating member (1230a), and the second sealing member (1260b) protrudes toward the injection unit (1300) more than the second insulating member (1230b).
  • first sealing member (1260a) and the second sealing member (1260b) may be manufactured from a material having a large dimensional variability (e.g., flexible).
  • first sealing member (1260a) and the second sealing member (1260b) may be manufactured from rubber.
  • first and second insulating members (1230a, 1230b) may be manufactured from a material having a small dimensional variability (e.g., hard).
  • the first and second insulating members (1230a, 1230b) may be manufactured from Teflon.
  • Fig. 13 shows a process of assembling a first proposed temperature controller (1200) into a coolant injection device (1000).
  • a flow controller coupling part (1820) and an injection part coupling part (1810) are pressurized in a direction facing each other, and the pressurized injection part coupling part (1810) and the flow controller coupling part (1820) pressurize the temperature controller (1200).
  • the first sealing member (1260a) comes into contact with one surface of the flow regulator coupling portion (1820) or the flow regulator (1100), and the second sealing member (1260b) comes into contact with one surface of the injection portion coupling portion (1810), so that the first sealing member (1260a) and the second sealing member (1260b) are pressurized. Then, the lengths of the first and second sealing members (1260a, 1260b) that are pressurized are reduced in the direction of the central axis. At this time, the first and second sealing members (1260a, 1260b) spread near the area where the flow path is formed.
  • first and second sealing members (1260a, 1260b) have large dimensional variability, and the outer surfaces of the first and second sealing members (1260a, 1260b) are blocked by the first and second insulating members (1230a, 1230b), respectively, so that the shapes of the first and second sealing members (1260a, 1260b) are deformed so as to spread to the area where the flow path is formed by the force that presses the first and second sealing members (1260a, 1260b).
  • deformation of the first and second sealing members (1260a, 1260b) can further strengthen the sealing of the flow path.
  • the first sealing member (1260a) and the second sealing member (1260b) can be pressurized until the flow controller coupling part (1820) and the spray unit coupling part (1810) are coupled as shown in Fig. 13(c).
  • the temperature controller (1200) can be fixed within the internal space formed by the coupling of the spray unit coupling part (1810) and the flow controller coupling part (1820) by the force of the flow controller coupling part (1820) or the flow controller (1100) pressing the first sealing member (1260a) and the force of the spray unit coupling part (1810) pressing the second sealing member (1260b).
  • a gap may be formed between the first insulating member (1230a) and the flow controller coupling (1820) or the flow controller (1100), and a gap may also be formed between the second insulating member (1230b) and the spray unit coupling (1810).
  • the temperature controller (1200) is fixed and stably assembled by the force with which the flow controller coupling (1820) or the flow controller (1100) presses the first sealing member (1260a) and the force with which the spray unit coupling (1810) presses the second sealing member (1260b).
  • the flow controller coupling part (1820) and the injection unit coupling part (1810) can be completely coupled.
  • the first and second sealing members (1260a, 1260b) use a material with a large dimensional variability, the compressive stress is small. Accordingly, damage to the temperature controller (1200) that may occur while pressurizing the flow controller coupling part (182) and the injection unit coupling part (1810) can be prevented.
  • a temperature controller (1200) proposed to solve the above-described problem may include a body (1210), a thermoelectric element (1220), and a sealing member (1260).
  • the definitions of one end and the other end of the body (1210), the arrangement, function, and operation of the thermoelectric element (1220), and the arrangement, material, and shape of the sealing member (1260) are the same as those described in “[3] First proposed temperature controller (1200),” and therefore, the description is omitted.
  • the definitions and meanings of terms that are not separately defined or described in the description of the present embodiment should be interpreted as the definitions and meanings of terms described in “[3] First proposed temperature controller (1200).”
  • the second proposed temperature controller (1200) is identical to the first proposed temperature controller (1200) except that the first insulating member (1230a) and the second insulating member (1230b) are absent. Meanwhile, since the first insulating member (1230a) and the second insulating member (1230b) are absent, it should be understood that the first sealing member (1260a) protrudes outward from the body (1210) in the direction of the central axis more than one end of the body (1210), and the second sealing member (1260b) protrudes outward from the body (1210) in the direction of the central axis more than the other end of the body (1210).
  • the first sealing member (1260a) protrudes toward the coolant storage (2000) more than one end of the body (1210)
  • the second sealing member (1260b) protrudes toward the injection unit (1300) more than the other end of the body (1210).
  • the transfer to other components of the coolant injection device (1000) through the outer surface of the body (1210) e.g., the second portion and the third portion
  • the air gap created when the second proposed temperature controller (1200) is assembled acts as an insulating member.
  • the temperature controller (1200) is coupled by pressurizing the sprayer coupling part (1810) and the flow controller coupling part (1820) while facing each other.
  • the temperature controller (1200) is assembled and fixed in the internal space created when the sprayer coupling part (1810) and the flow controller coupling part (1820) are coupled.
  • the length in the direction of the central axis of the internal space created when the injection unit coupling part (1810) and the flow controller coupling part (1820) are pressurized is longer by (d1+d3) than the length from one end to the other end of the body (1210), and the length in the direction perpendicular to the central axis of the internal space is longer by (d2+d4) than the length in the direction perpendicular to the central axis of one end (and the other end) of the body (1210).
  • the temperature controller (1200) when the temperature controller (1200) is fixed to the internal space created when the injection unit coupling portion (1810) and the flow controller coupling portion (1820) are pressurized, an air gap can be formed between the internal space and the temperature controller (1200). Since air has low thermal conductivity, it can replace the role of the insulating member described above. That is, by using air as an insulating member, it is possible to prevent heat transferred to the body (1210) through the thermoelectric element (1220) from being transferred to other components of the coolant injection device (1000) through the outer surface of the body (1210) (e.g., the second portion and the third portion).
  • the flow controller coupling part (1820) and the injection part coupling part (1810) can be completely coupled even if there is a manufacturing tolerance, and damage that may be applied to the temperature controller (1200) due to the small compressive stress of the first and second sealing members (1260a, 1260b) can be prevented, as described above.
  • the third proposed temperature controller (1200) may be configured similarly to the temperature controller (1200) described in FIG. 4 and FIG. 5 and [Configuration of Temperature Controller (1200)].
  • the third proposed temperature controller (1200) may include a body (1210), a thermoelectric element (1220), and an insulating member (1230).
  • the difference from the temperature controller (1200) described in [Configuration of Temperature Controller (1200)] is that the first insulating member (1230a) and the second insulating member (1230b) are composed of a material with large numerical variability and flexibility, such as rubber, rather than a hard material with small numerical variability, such as Teflon. Meanwhile, the coolant injection device (1000) using the third proposed temperature controller (1200) can also be assembled in the same manner as described in “[4] Assembly of the coolant injection device (1000) using the first proposed temperature controller (1200).”
  • first insulation member (1230a) and the second insulation member (1230b) can be modified similarly to the first and second sealing members (1260a, 1260b) described in “Assembly of a coolant injection device (1000) using a first proposed temperature controller (1200)” [4].
  • the first insulating member (1230a) comes into contact with one side of the flow regulator coupling portion (1820) or the flow regulator (1100)
  • the second insulating member (1230b) comes into contact with one side of the injection portion coupling portion (1810)
  • the first insulating member (1230a) and the second insulating member (1230b) are pressurized.
  • the lengths of the first and second insulating members (1230a, 1230b) that are pressurized are reduced in the direction of the central axis.
  • the first and second insulating members (1230a, 1230b) spread near the area where the flow path is formed.
  • Such deformation of the first and second insulating members (1230a, 1230b) can further strengthen the sealing of the flow path, as described above.
  • the flow controller coupling part (1820) and the injection unit coupling part (1810) can be completely coupled.
  • damage to the temperature controller (1200) can be prevented due to the small compressive stress of the first and second insulating members (1230a, 1230b).
  • the first insulating member (1230a) and the second insulating member (1230b) are pressurized until the flow controller coupling member (1820) and the spray unit coupling member (1810) are coupled, and the temperature controller (1200) can be fixed to the internal space formed by the coupling of the spray unit coupling member (1810) and the flow controller coupling member (1820) by the force of the flow controller coupling member (1820) or the flow controller (1100) pressing the first insulating member (1230a) and the force of the spray unit coupling member (1810) pressing the second insulating member (1230b).
  • Example 3 Configuration of a coolant injection device (1000) to reduce power consumption
  • the overall configuration of the coolant injection device (1000) was described through Fig. 3.
  • the power supply unit (1500) is a rechargeable battery
  • the number of times the coolant injection device (1000) can be injected with a single charge is closely related to the convenience of use of the coolant injection device (1000).
  • the cycle that requires battery charging can be increased.
  • the gap in use during which the coolant injection device (1000) cannot be used while charging the battery can be reduced.
  • the number of charging times decreases, and through this, the lifespan of the battery can be expected to be extended.
  • a method of increasing the battery capacity may be considered in order to increase the number of injections of the coolant injection device (1000) that can be used with one charge of the battery.
  • the size of the battery increases and the weight of the battery increases. This means that the size and weight of the coolant injection device (1000) increase.
  • the increase in the size and weight of the coolant injection device (1000) reduces the usability of the coolant injection device (1000) and reduces portability. Therefore, a method is needed to reduce the power consumption of the coolant injection device (1000) without increasing the battery capacity.
  • control method or control algorithm for heating the coolant by the coolant injection device (1000) may be modified.
  • modifying the control algorithm to reduce the power consumption may require considerable effort from the developer.
  • the heating efficiency of the temperature controller (1200) when the coolant is heated through the temperature controller (1200) and then meets the flow controller (1100) is higher than the heating efficiency when the coolant is heated by the temperature controller (1200) after passing through the flow controller (1100).
  • FIG. 18 shows an example of a configuration of a coolant injection device (1000), and FIG. 19 shows a configuration of a coolant injection device (1000) according to Example 3.
  • the coolant injection device (1000) may include a flow controller (1100), a temperature controller (1200), an injection unit (1300), a controller (1400), a power supply (1500), a temperature sensor (1600), and an I/O interface (1700), as described in FIG. 3.
  • the I/O interface (1700) may include an input unit (1710) and an output unit (1720).
  • the coolant injection device (1000) may further include a coolant reservoir coupling portion (1830). Since the coolant reservoir coupling portion (1830) is the same as the coolant reservoir coupling portion (1830) described in FIG. 10, its description is omitted. Meanwhile, it should be understood that the coolant reservoir coupling portion (1830) is coupled with the coolant reservoir (2000).
  • the temperature controller (1200) and the flow controller (1100) are interposed between the coolant storage coupling portion (1830) and/or the coolant storage (2000) and the injection portion (1300).
  • the order in which the temperature controller (1200) and the flow controller (1100) are interposed between the coolant storage coupling portion (1830) and/or the coolant storage (2000) and the injection portion (1300) is different in FIGS. 18 and 19, and this will be examined.
  • the flow controller (1100), the temperature controller (1200), and the injection unit (1300) are fluidically connected in that order.
  • the coolant provided from the coolant storage (2000) passes through the flow controller (1100), is heated in the temperature controller (1200), and is injected through the injection unit (1300). That is, the temperature controller (1200) is placed between the flow controller (1100) and the injection unit (1300).
  • the temperature controller (1200), the flow controller (1100), and the injection unit (1300) are fluidically connected in that order.
  • the coolant provided from the coolant storage (2000) is heated in the temperature controller (1200) before passing through the flow controller (1100), and the heated coolant passes through the flow controller (1100) and is injected through the injection unit (1300).
  • the flow controller (1100) is disposed between the temperature controller (1200) and the injection unit (1300).
  • the temperature controller (1200) is disposed between the flow controller (1100) and the coolant storage unit (2000) and/or the coolant storage coupling unit (1830) described in FIG. 10.
  • the coolant injection device (1000) of FIG. 19 is configured such that the temperature controller (1200) is closer to the coolant storage coupling (1830) and/or the coolant storage (2000) than the coolant injection device (1000) of FIG. 18.
  • the arrangement of the temperature controller (1200) and the flow controller (1100) such as the coolant injection device (1000) of FIG. 19 can increase the heating efficiency for the coolant compared to the arrangement of the temperature controller (1200) and the flow controller (1100) such as the coolant injection device (1000) of FIG. 18.
  • the increased heating efficiency can reduce the power consumption provided to the temperature controller (1200).
  • a handpiece-type coolant injection device (hereinafter, “comparison subject”) was prepared in which a heater and a valve were placed between the cartridge and the nozzle, but the heater was placed between the valve and the nozzle.
  • the coolant was configured to be discharged from the cartridge, passed through the valve, and then heated by the heater.
  • the heater was used as a heater including a porous sintered primary heat transfer medium applied to and sold by the conventional License Medical Company's TargetCool.
  • a hand piece type coolant injection device (hereinafter, “experimental subject”) was prepared in which a heater and a valve were arranged between a cartridge and a nozzle, and the heater was arranged between the valve and the cartridge.
  • the coolant was configured to be discharged from the cartridge, heated by the heater, and then passed through the valve. Meanwhile, the heater was used as a heater including a porous sintered primary heat transfer medium applied to and sold by the conventional License Medical Company's TargetCool.
  • Liquid CO2 was used as a coolant for both the control and experimental subjects.
  • the target temperature was set to 5 degrees, and the coolant was sprayed on the skin.
  • the location of the skin on which the coolant was sprayed was moved, and the coolant was sprayed again until the target temperature of 5 degrees was reached.
  • Fig. 20(a) is data showing the results of measuring the skin temperature and TEC input value (i.e., PWM duty ratio) when the coolant spraying device, which is the subject of the experiment, is used
  • Fig. 20(b) is data showing the results of measuring the skin temperature and TEC input value (i.e., PWM duty ratio) when the coolant spraying device, which is the subject of the comparison, is used.
  • the TEC input maximum value of Fig. 20(a) is 13.2% on average
  • the TEC input maximum value of Fig. 20(b) is 18.35% on average. That is, it can be seen that the power consumption of the coolant injection device, which is the subject of the experiment, is reduced by 5.15% compared to the power consumption of the coolant injection device, which is the subject of the comparison.
  • the coolant when the coolant is discharged from the cartridge, some of the coolant is vaporized due to the pressure change, so that the liquid ratio decreases and the gas ratio increases. At this time, as it moves from the cartridge to the nozzle, the liquid ratio contained in the coolant continuously decreases and the gas ratio continuously increases. Since the thermal conductivity of the liquid is higher than that of the gas, as the liquid ratio decreases, the power required to heat the coolant increases.
  • the gas ratio of the coolant contained in the coolant can significantly increase when the coolant is heated by the heater.
  • the distance between the heater and the cartridge increases, so the gas ratio in the coolant increases further.
  • the gas ratio of the coolant is relatively high, and in the case of the experimental subject, the liquid ratio contained in the coolant is high compared to the comparison subject. Therefore, the heating performance of the experimental subject increases compared to the comparison subject. In addition, due to the increased heating performance, the power consumption of the experimental subject decreases compared to the comparison subject.
  • the temperature controller (1200) Based on the difference between the temperature of the target area and the target temperature, the temperature controller (1200) heats the coolant, and after the coolant is heated, it is sprayed into the target area through the spray unit (1300). At this time, the time until the heated coolant is sprayed from the temperature controller (1200) through the spray unit (1300) is called the delay time.
  • this delay time causes a difference between the time when the temperature controller (1200) heats the coolant based on the temperature of the measured target area and the time when the heated coolant reaches the target area, so that the coolant, whose temperature is controlled based on the temperature of the measured target area, does not immediately cool the target area. Accordingly, there was a problem in that the cooling of the coolant, which is heated based on the temperature of the target area measured by the temperature sensor (1600), was not immediately reflected in the cooling of the target area.
  • the delay time occurring in the coolant injection device (1000) can be statistically calculated, and the PID (Proportional-Integral-Differential) control constant can be adjusted by considering the calculated statistical value.
  • the temperature controller (1200) heats the coolant
  • the changing temperature of the target area is measured, and the difference value between the measured temperature and the target temperature is input into the PID feedback function to determine the power to be applied to the temperature controller (1200) next time.
  • the power to be applied to the temperature controller (1200) is determined.
  • the delay time can be compensated by changing at least one of Cp, Ci, and Cd.
  • the PID feedback constants Cp, Ci, and Cd
  • the obtained statistical values can be the average value, mode value, maximum value, or standard deviation value of the delay times obtained through repeated cooling experiments.
  • the controller (1400) may control the temperature controller (1200) to heat the coolant based on a temperature that is a certain value higher than the set target temperature using the generated statistical values, thereby preventing the temperature inversion phenomenon.
  • the delay time increases as the amount of coolant remaining between the temperature controller (1200) and the injection unit (1300) that was not injected at the previous injection point increases. That is, if the flow path from the temperature controller (1200) to the injection unit (1300) is small so that the amount of coolant remaining can be reduced, the delay time can be reduced. Therefore, the length and/or volume of the flow path from the temperature controller (1200) to the injection unit (1300) can be designed to be less than a predetermined value, thereby reducing the delay time.
  • the diameter that can minimize the delay time can be found, and the design can be made with the corresponding diameter.
  • a handpiece-type coolant injection device (hereinafter, “comparative subject”) was prepared in which a heater and a valve were placed between the cartridge and the nozzle, but the heater was placed between the valve and the nozzle.
  • Example 4 a hand piece type coolant injection device (hereinafter referred to as “experimental subject”) was prepared in which a heater and a valve were placed between the cartridge and the nozzle, and the heater was placed between the valve and the cartridge.
  • the coolant was configured to be discharged from the cartridge, heated by the heater, and then passed through the valve. Meanwhile, the heater was used as a heater including a porous sintered primary heat transfer medium applied to and sold by the conventional License Medical Company's TargetCool.
  • Liquid CO2 was used as a coolant for both the control and experimental subjects.
  • the target temperature was set to 5 degrees, and the coolant was sprayed on the skin.
  • the time required for the skin temperature to reach the target temperature of 5 degrees was measured, and a total of 5 sprays were performed.
  • Figure 21(a) shows the time it takes for the coolant injection device, which is the subject of the experiment, to reach the target temperature
  • Figure 21(b) shows the time it takes for the coolant injection device, which is the subject of the comparison, to reach the target temperature
  • the delay time of the coolant injection device can be interpreted as 3.5 seconds.
  • the skin temperature reached the target temperature of 3 degrees before 3.5 seconds, the skin temperature did not maintain 5 degrees at that time, and the measured temperature dropped for a while, so it cannot be considered that the target temperature was reached.
  • the skin temperature reaches the target temperature of 5 degrees in 1.5 seconds and then maintains the target temperature of 5 degrees. As shown in Fig. 21(b), the skin temperature reaches the target temperature of 5 degrees in 1.5 seconds and then continues to maintain the target temperature of 5 degrees, so it can be seen that the target temperature is reached in 1.5 seconds.
  • a temperature controller (1200) included in a coolant injection device (1000) may have at least one configuration of Embodiment 1 and Embodiment 2.
  • a temperature controller (1200) that does not have a porous sintered structure heat transfer medium like Embodiment 1 may be included in the coolant injection device (1000) while the insulation member and sealing member of the temperature controller (1200) are arranged at one end and one end of the body (1210) like any one of the configurations disclosed in Embodiment 2 (hereinafter, “first temperature controller”).
  • the insulating member and sealing member of the temperature controller (1200) may be arranged at one end and one end of the body (1210) as in any one of the configurations disclosed in Example 2, and a temperature controller (1200) having a porous sintered structure heat transfer medium as shown in [Configuration of Temperature Controller (1200)] may be included in the coolant injection device (1000) (hereinafter, “second temperature controller”).
  • first temperature controller or the second temperature controller may be disposed within the coolant injection device (1000) according to embodiment 3.
  • first temperature controller or the second temperature controller may be disposed between the flow controller (1100) and the injection portion (1300), as described in FIG. 18.
  • first temperature controller or the second temperature controller may be disposed between the flow controller (1100) and the coolant reservoir (2000) (or the coolant reservoir coupling portion (1830)), as described in FIG. 19.
  • the temperature controller (1200) having a porous sintered structure heat transfer medium may be placed between the flow controller (1100) and the injection unit (1300) as described in FIG. 18, or between the flow controller (1100) and the coolant storage (2000) (or the coolant storage coupling unit (1830)) as described in FIG. 19.
  • a temperature controller having at least one of the configurations of Embodiment 1 and Embodiment 2 as described above or a coolant injection device (1000) in which a temperature controller described in [Configuration of Temperature Controller (1200)] is arranged may be applied with at least one of the methods described in “[2] Method for Solving Delay Time” to reduce the delay time according to Embodiment 4.

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Abstract

L'invention divulgue un dispositif de pulvérisation de fluide caloporteur pour pulvériser un fluide caloporteur. En particulier, le dispositif de pulvérisation de fluide caloporteur peut comprendre : une cartouche qui fournit le fluide caloporteur ; une buse qui est en communication fluidique avec la cartouche et qui pulvérise le fluide caloporteur, fourni à partir de la cartouche, sur la zone cible ; un dispositif de chauffage qui est intercalé entre la cartouche et la buse et qui chauffe le fluide caloporteur transporté de la cartouche à la buse ; et une soupape qui est intercalée entre la cartouche et la buse et qui permet de transporter le fluide caloporteur, amené à sortir de la cartouche, vers la buse, le dispositif de chauffage pouvant être disposé entre la soupape et la cartouche de telle sorte que le fluide caloporteur arrive à la soupape après avoir été chauffé.
PCT/KR2024/015767 2023-10-19 2024-10-17 Dispositif de pulvérisation de fluide caloporteur Pending WO2025084811A1 (fr)

Applications Claiming Priority (6)

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KR20230139956 2023-10-19
KR10-2023-0139956 2023-10-19
KR10-2023-0194642 2023-12-28
KR20230194642 2023-12-28
KR1020240123608A KR20250057629A (ko) 2023-10-19 2024-09-11 냉각제 분사 장치
KR10-2024-0123608 2024-09-11

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011212451A (ja) * 2001-05-23 2011-10-27 Palomar Medical Technologies Inc 光美容装置のための冷却システム
KR20180109827A (ko) * 2016-11-15 2018-10-08 울산과학기술원 국부 냉각 장치, 국부 냉각 장치의 제어 방법 및 국부 냉각 장치의 냉각 온도 조절기
KR20190106664A (ko) * 2018-03-08 2019-09-18 주식회사 요즈마비엠텍 히터 온도 조절 기능을 갖는 극저온 치료기
KR20200124635A (ko) * 2020-10-20 2020-11-03 주식회사 리센스메디컬 의료용 냉각장치
KR20220008730A (ko) * 2020-07-14 2022-01-21 주식회사 리센스메디컬 의료용 냉각 시스템 및 이를 이용하는 의료용 냉각 장치

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011212451A (ja) * 2001-05-23 2011-10-27 Palomar Medical Technologies Inc 光美容装置のための冷却システム
KR20180109827A (ko) * 2016-11-15 2018-10-08 울산과학기술원 국부 냉각 장치, 국부 냉각 장치의 제어 방법 및 국부 냉각 장치의 냉각 온도 조절기
KR20190106664A (ko) * 2018-03-08 2019-09-18 주식회사 요즈마비엠텍 히터 온도 조절 기능을 갖는 극저온 치료기
KR20220008730A (ko) * 2020-07-14 2022-01-21 주식회사 리센스메디컬 의료용 냉각 시스템 및 이를 이용하는 의료용 냉각 장치
KR20200124635A (ko) * 2020-10-20 2020-11-03 주식회사 리센스메디컬 의료용 냉각장치

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