[go: up one dir, main page]

WO2025068692A1 - Inhalateur - Google Patents

Inhalateur Download PDF

Info

Publication number
WO2025068692A1
WO2025068692A1 PCT/GB2024/052469 GB2024052469W WO2025068692A1 WO 2025068692 A1 WO2025068692 A1 WO 2025068692A1 GB 2024052469 W GB2024052469 W GB 2024052469W WO 2025068692 A1 WO2025068692 A1 WO 2025068692A1
Authority
WO
WIPO (PCT)
Prior art keywords
retaining
canister
cam
cam surface
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/GB2024/052469
Other languages
English (en)
Inventor
Stephen John Marshall
Sanjay NARSHBHAI
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3D Engineering Design Ltd
Original Assignee
3D Engineering Design Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3D Engineering Design Ltd filed Critical 3D Engineering Design Ltd
Publication of WO2025068692A1 publication Critical patent/WO2025068692A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0001—Details of inhalators; Constructional features thereof
    • A61M15/0021—Mouthpieces therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0065—Inhalators with dosage or measuring devices
    • A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
    • A61M15/008—Electronic counters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00—Devices for influencing the respiratory system of patients by gas treatment, e.g. ventilators; Tracheal tubes
    • A61M16/0003—Accessories therefor, e.g. sensors, vibrators, negative pressure
    • A61M2016/0015—Accessories therefor, e.g. sensors, vibrators, negative pressure inhalation detectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/10—General characteristics of the apparatus with powered movement mechanisms
    • A61M2205/106—General characteristics of the apparatus with powered movement mechanisms reciprocating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2230/00—Measuring parameters of the user
    • A61M2230/40—Respiratory characteristics

Definitions

  • the present invention relates to inhalers.
  • the present invention relates to inhalers for multiple use.
  • Inhalers for delivering a dose of medicament to a user to alleviate symptoms of a condition are known, e.g., for asthma.
  • Such devices typically include a main body including a pathway and a container, e.g., a canister for a pressured Metered Dose Inhaler (pMDI) or dry powder packaging I blister packs, which contains medicament which is dispensed into the pathway for a user to inhale.
  • pMDI pressured Metered Dose Inhaler
  • dry powder packaging I blister packs which contains medicament which is dispensed into the pathway for a user to inhale.
  • the devices are designed to be used whilst there is medicament in the canister and then disposed of once the canister is depleted. Disposal of an inhaler which is otherwise functional is wasteful. Further, such disposal of inhalers prevents further development of advantageous features on inhalers which would be too expensive to adopt on a disposable device.
  • the present invention seeks to address one or more of the above problems.
  • an inhaler including: a main body; a chamber for receipt of a canister containing medicament; a delivery pathway into which medicament may be delivered to a user; a delivery pathway opening fluidly connected to the delivery pathway through which the user may inhale the medicament; a nozzle for dispensing the medicament into the delivery pathway, said nozzle including a nozzle opening through which the medicament is dispensed; a medicament dispensing pathway fluidly connectable to the canister received in the chamber; and a mechanism for moving the canister relative to the chamber; wherein the mechanism is configurable to move the canister from a first, retracted, state to a second, extended, state.
  • the mechanism may be further configurable to move the canister from the second, extended, state to the first, retracted, state.
  • the mechanism may cause the canister to move linearly from the first, retracted, state to the second, extended, state, or between the first and second states.
  • the mechanism may be further configurable to move the canister to a third, medicament dispensing, state.
  • the first state may be positioned between the second and third states.
  • the mechanism may cause the canister to move linearly from the first state to the third state.
  • the mechanism may cause the canister to move linearly between the first and third states.
  • the mechanism may include a drive member for causing the mechanism to move between the first and second states.
  • the drive member may be a motor.
  • the mechanism may include a transmission member for transmitting drive from the drive member to the canister.
  • the drive member may be rotatably connected to the transmission member.
  • the drive member may include a first gear and the transmission member may include a second gear meshed with the first gear.
  • the second gear may be larger than the first gear.
  • the transmission member may include a base and the second gear may extend around a periphery of the base.
  • an inhaler including: a main body; a chamber for receipt of a canister containing medicament; a delivery pathway into which medicament may be delivered to a user; a delivery pathway opening fluidly connected to the delivery pathway through which the user may inhale the medicament; a nozzle for dispensing the medicament into the delivery pathway, said nozzle including a nozzle opening through which the medicament is dispensed; a medicament dispensing pathway fluidly connectable to the canister received in the chamber; and a mechanism for moving the canister relative to the chamber; wherein the mechanism is configurable to move the canister from a first, retracted, state to a second, extended, state; and where the transmission member may include a protrusion.
  • the mechanism may include a cam member including a cam surface on which the protrusion rests.
  • Rotational movement of the transmission member may cause linear movement of the cam member to cause the mechanism to move between first and second positions.
  • the transmission member may further include a roller positioned on the protrusion permitted to rotate relative to the protrusion.
  • the roller may rest on the cam surface.
  • the cam surface may extend circumferentially around the cam member, at least partially.
  • the cam member may include a top and a bottom wherein the bottom may be positioned closer to the medicament dispensing pathway than the top.
  • the cam member may include a sidewall which may extend between the top and the bottom.
  • the cam surface may extend between the top and bottom of the cam member along the sidewall.
  • the cam surface may include a first cam surface portion which extends upwardly from the bottom of the cam member.
  • the first cam surface portion may extend generally helically upwardly from the bottom of the cam member.
  • the cam surface may include a second cam surface portion which is generally parallel to the top and / or bottom of the cam member.
  • the second cam surface portion may be connected to the first cam surface portion.
  • the cam surface may include a third cam surface portion which extends generally downwardly from the top of the cam member.
  • the third cam surface portion may extend generally helically downwardly from the top of the cam member.
  • the third cam surface portion may be connected to the second cam surface portion.
  • the cam surface may be formed as a groove I recess I slot in the sidewall.
  • the transmission member may include: a transmission member base; and a transmission member sidewall which may extend upwardly away from the base, said sidewall defining a recess in the transmission member.
  • the sidewall may extend upwardly generally orthogonally away from the base.
  • the protrusion may be positioned within the recess.
  • the cam member may be received within the transmission member.
  • the mechanism may include a retaining member for retaining the canister relative to the mechanism.
  • the retaining member may be attached to the cam member in use to retain the canister relative to the cam member.
  • the retaining member may be generally annular / ring shaped in plan view.
  • the retaining member may extend generally circumferentially around the canister, in use.
  • the retaining member may include a plurality of retaining portions for retaining the canister.
  • the retaining portions may be movable between a first condition in which the retaining portions permit the canister to move relative to the retaining member and a second condition in which the retaining portions retain the canister relative to the retaining member.
  • the retaining portions may be biased to adopt the first condition.
  • the retaining member may include a locking member for locking the retaining portions in the second condition.
  • the retaining member may be a collet and the locking member may be a locking ring which extends over the collet to urge the retaining portions into the second condition.
  • One or more or all the features of the second aspect of the invention may be incorporated into the first aspect of the invention.
  • an inhaler including: a main body; a chamber for receipt of a canister containing medicament; a delivery pathway into which medicament may be delivered to a user; a delivery pathway opening fluidly connected to the delivery pathway through which the user may inhale the medicament; a nozzle for dispensing the medicament into the delivery pathway, said nozzle including a nozzle opening through which the medicament is dispensed; a medicament dispensing pathway fluidly connectable to the canister received in the chamber; and a mechanism for moving the canister relative to the chamber; wherein the mechanism is configurable to move the canister from a first, retracted, state to a second, extended, state; and the transmission member may include: a transmission member base; and a transmission member sidewall which may extend upwardly away from the base, said sidewall defining a recess in the transmission member.
  • the sidewall may extend upwardly generally orthogonally away from the base.
  • the sidewall may include a cam surface.
  • the cam surface may be positioned within the recess.
  • the cam surface may extend generally helically around the sidewall.
  • the inhaler may further include a retaining member for retaining the canister relative to the mechanism.
  • the retaining member may include a protrusion which, in use, rests on the cam surface.
  • the retaining member may be generally annular / ring shaped in plan view.
  • the retaining member may extend generally circumferentially around the canister, in use.
  • the retaining member may include a plurality of retaining portions for retaining the canister.
  • the retaining portions may be movable between a first condition in which the retaining portions permit the canister to move relative to the retaining member and a second condition in which the retaining portions retain the canister relative to the retaining member.
  • the retaining portions may be biased to adopt the first condition.
  • the retaining member may include a locking member for locking the retaining portions in the second condition.
  • the retaining member may be a collet and the locking member may be a locking ring which extends over the collet to urge the retaining portions into the second condition.
  • the inhaler may include a biasing member for biasing the retaining member to move away from the locking member to cause the locking member to abut the retaining portions of the retaining member.
  • the biasing member may be a spring.
  • the inhaler may include a roller positioned on the protrusion and permitted to rotate relative to the protrusion.
  • the roller may rest on the cam surface.
  • the inhaler may include a guide member for guiding the protrusion along the cam surface.
  • the guide member may include a slot through which the protrusion extends in use.
  • the guide member may be received within the recess of the transmission member.
  • the slot may be generally linear and / or may extend generally vertically.
  • the guide member in use, may stay in position as the transmission member rotates to cause the mechanism to move between first and second positions.
  • the inhaler may include a plurality of protrusions.
  • Each of the plurality of protrusions may each include a respective roller.
  • Each respective roller may be permitted to rotate relative to the protrusion and I or may rest on the cam surface.
  • the inhaler may include a plurality of cam surfaces.
  • Each of the plurality of cam surfaces may be positioned within the recess.
  • Each of the plurality of cam surfaces may extend generally helically around the sidewall.
  • the inhaler may include a plurality of slots.
  • Each of the plurality of protrusions may extend through a respective slot of the plurality of slots.
  • Each of the plurality of slots may be generally linear and I or may extend generally vertically.
  • One or more or all the features of the third aspect of the invention may be incorporated into the first and / or second aspects of the invention.
  • FIGURE 1 is a perspective view of an inhaler in accordance with a first embodiment
  • FIGURE 2 is cutaway view of figure 1 along a generally vertical plane
  • FIGURE 3 is a further cutaway view of figure 1 along a generally vertical plane with the lid in a closed position;
  • FIGURE 4 is the view of figure 3 with the lid in an open position
  • FIGURE 5 is a perspective view of the mechanism of the inhaler of figure 1 ;
  • FIGURE 6 is an exploded view of part of figure 5;
  • FIGURE 7 is a perspective view of the transmission member of figure 6;
  • FIGURE 8 is a perspective view of the cam member of figure 6;
  • FIGURE 9 is a perspective view of the retaining member of figure 6;
  • FIGURE 10 is a perspective view of the locking member of figure 6;
  • FIGURE 11 is a perspective view of a mechanism according to a second embodiment
  • FIGURE 12 is an exploded view of figure 11 ;
  • FIGURE 13 is a perspective view of the transmission member of figure 12;
  • FIGURE 14 is a perspective view of the retaining member of figure 12;
  • FIGURE 15 is a perspective view of the locking member of figure 12.
  • FIGURE 16 is a perspective view of the guide member of figure 12.
  • the inhaler 10 includes a main body 12.
  • the main body 12 may include a front 120, a rear 122, first and second respective sides, 124, 126 and a top and a bottom 128, 130.
  • the rear 122 and the top 128 may be connected by a generally curved surface 132 which extends therebetween.
  • the rear 122 and the bottom 130 may be connected by a further generally curved surface 134 which extends therebetween. These may be advantageous in improving the ergonomics of the inhaler 10 and its ease of manufacture.
  • the inhaler may be a pressured metered dose inhaler (pMDI).
  • the inhaler may be a dry powder inhaler (DPI).
  • the inhaler includes a chamber 14 for receipt of a medicament (see figure 2).
  • the chamber may be defined at least partially by the main body 12.
  • the chamber 14 may be configured to receive a container 16 containing medicament.
  • the container may be a canister 16.
  • the canister 16 may contain pressurised medicament.
  • the container may be packaging such as a blister pack or other packaging for receipt of a dry powder.
  • the canister 16 may be replaceable, e.g., if the medicament has been used or if a different medicament or product is required.
  • the canister 16 may include a valve stem 160 (see figure 4).
  • the chamber 14 may be generally cylindrical. In embodiments the chamber 14 may be other shapes without departing from the scope of the present disclosure. For example, the chamber 14 may be cube, cuboidal or prismatic or another three dimensional shape without departing from the scope of the present disclosure.
  • the inhaler 10 may include electronics to assist a user in effectively administering a dose of medicament. The inhaler 10 may therefore be switched off and on as required.
  • a button 30 on the inhaler may be pressed for a predetermined period of time, e.g., 3 seconds, to switch on the inhaler and I or switch off the inhaler 10.
  • the inhaler 10 may include a battery 70 which may be rechargeable. The battery 70 may be positioned adjacent the bottom 130 of the main body 12.
  • the inhaler 10 may include a screen 60 to display information about the inhaler 10 to a user. For example, the screen 60 may show how many doses are remaining in a canister, the number of doses administered, time since last use, the percentage of battery charge remaining, etc.
  • the screen 60 may be positioned on the front 120 of the main body 12.
  • the screen 60 may be generally rectangular.
  • the button 30 may be positioned below the screen 60.
  • the button 30 may be positioned on the front 120 of the main body 12.
  • the inhaler 10 may include first and second respective modes. In a first mode, the inhaler 10 may be in a “dispensing” mode to dispense medicament to a user. In a second mode, the inhaler 10 may be in a “spirometry” mode to permit a user to measure the volume and I or speed (flow) of air that can be inhaled or exhaled by the user.
  • the inhaler 10 may include a spirometry sensor 1000 to permit spirometry readings to be taken in the “spirometry” mode.
  • the spirometry sensor 1000 may be a pressure or flow sensor.
  • the chamber 14 may be covered by a chamber cover / lid 18.
  • an opening of the chamber may be covered by a chamber cover / lid 18.
  • the opening of the chamber 14 may be generally circular in plan view.
  • the opening of the chamber may be other shapes without departing from the scope of the present disclosure.
  • the opening may be triangular, ovular, square or rectangular or another polygonal shape in plan view.
  • the chamber may not be covered by a chamber cover / lid 18.
  • the lid 18 may be movably connected to the main body 12 to permit the lid 18 to move between open and closed conditions (see figures 4 and 3 respectively).
  • the lid 18 may be biased to adopt the open condition.
  • the lid 18 may be pivotally connected to the main body 12.
  • the lid 18 may be slidably or rotatably connected to the main body 12 without departing from the scope of the present disclosure.
  • the lid may be provided with a latch 13 which latches to a portion of the main body 12 to hold the lid 18 in a closed condition.
  • the latch may be user operable so a user may replace a canister when desired.
  • the button 30 or a further button may operate the latch to cause the lid 18 to adopt the open condition.
  • a slidable button to operate the latch may be provided on the lid 18.
  • the inhaler 10 may include a controller 20 which may control the lid 18.
  • the controller 20 may control the latch to cause the lid 18 to adopt the open condition if a predetermined criterion is met, e.g., the canister is empty, a predetermined number of doses or volume of medicament has been administered from the canister, a predetermined time period has elapsed.
  • the lid 18 may be substantially circular in plan view. In embodiments, the lid 18 may be square or rectangular or any other polygonal shape without departing from the scope of the present disclosure.
  • the inhaler 10 may include a mouthpiece 40 which in use may be received in a user’s mouth.
  • the mouthpiece 40 may be positioned at a bottom of the main body 12, e.g., opposite the lid 18. In embodiments, the mouthpiece 40 may be positioned at a top or generally centrally of the main body 12 without departing from the scope of the present disclosure.
  • the mouthpiece 40 may extend generally away from the main body 12.
  • the mouthpiece 30 may extend generally away from the front 120 of the main body 12.
  • the mouthpiece 40 may extend generally linearly away from the main body 12, or the front 120 of the main body 12.
  • the mouthpiece 40 may extend away from the main body 12 at an angle generally inclined to the main body 12, e.g., the front 120 of the main body 12. In embodiments, the mouthpiece may extend generally orthogonally away from the main body 12, or the front 120 of the main body 12.
  • the mouthpiece may be generally oval, elliptical or stadium shaped in cross-section. This has been found to be advantageous for a user to effectively seal their mouth against the mouthpiece 40 and therefore effectively administer a dispensed dose of medicament to the user.
  • the mouthpiece may be triangular, square, rectangular, hexagonal, octagonal, circular or another polygonal shape in cross-section without departing from the scope of the present disclosure.
  • the inhaler 10 may include a pathway opening cover, or mouthpiece cover 400.
  • the mouthpiece cover 400 may extend over at least a portion, and preferably all, the mouthpiece 40 to cover the mouthpiece 40.
  • the mouthpiece cover 400 may be a complementary shape to the mouthpiece 40 to cover the mouthpiece 40.
  • the mouthpiece cover 400 may taper as it extends away from the main body 12 over the mouthpiece 40.
  • the mouthpiece cover 400 may be pivotably attached to the main body 12 at a pivot point 402.
  • the pivot point 402 may be positioned adjacent the bottom 130 of the main body 12.
  • the mouthpiece cover 400 may be movably attached in other or additional ways to the main body 12, e.g., slidably attached, rotatably attached.
  • the mouthpiece cover 400 may be removable from the main body 12.
  • the mouthpiece cover 400 may be movable between an open condition in which a user may use the mouthpiece 40 and a closed condition in which a user is prevented from using the mouthpiece 40.
  • the mouthpiece cover 400 may be used instead of the button 30 to switch on the inhaler 10.
  • the inhaler 10 includes a delivery pathway 50 into which medicament may be delivered for a user (shown in figure 2).
  • the pathway 50 may extend along the main body 12 adjacent the bottom 130 of the inhaler 10. In embodiments, this may not be the case.
  • the pathway 50 may be positioned below the chamber 14 and / or above the battery 70.
  • the pathway 50 may extend generally linearly within the main body 12. In embodiments this may not be the case.
  • the pathway 50 includes a delivery pathway opening 502 fluidly connected to the pathway 50 through which a user may inhale a medicament or exhale.
  • the pathway 50 may extend into the mouthpiece 40.
  • the mouthpiece 40 may define at least a portion of the pathway 50.
  • the pathway opening 502 may be defined by the mouthpiece 40.
  • the pathway 50 may have a second pathway opening 504 which may act as an exhaust during exhalation or an inlet during inhalation.
  • the second pathway opening 504 may be covered by a grill or vent 506.
  • the grill or vent 506 may be positioned in, or be defined by, the rear 122 of the main body 12.
  • the inhaler includes a nozzle 80 for dispensing the medicament into the pathway 50 (see figures 2 to 4).
  • the nozzle 80 includes a nozzle opening 802 through which the medicament is dispensed.
  • the inhaler 10 includes a medicament dispensing pathway 100 fluidly connectable to the canister 16 received in the chamber 14 (see figure 4).
  • the medicament dispensing pathway 100 may be fluidly connected to the chamber 14.
  • An opening 1002 of the medicament dispensing pathway 100 may be positioned in a base 140 of the chamber 14.
  • the base 140 of the chamber 14 may include a recessed portion 142 for receipt of a portion of the canister 16.
  • the opening 1002 of the medicament dispensing pathway 100 may be positioned in the recessed portion 142.
  • the recessed portion 142 may be generally circular in plan view.
  • a further recessed portion 144 may be positioned in the base 140.
  • the further recessed portion 144 may be positioned within the recessed portion 142.
  • the further recessed portion 144 may be generally circular in plan view.
  • the further recessed portion 144 may be generally concentric with the recessed portion 142.
  • the further recessed portion 144 may be more recessed, e.g., have a greater depth, into the base 140 than the recessed portion 142.
  • the opening 1002 of the medicament dispensing pathway 100 may be positioned in the further recessed portion 144.
  • the medicament dispensing pathway 100 may be positioned in the nozzle 80. In embodiments, the medicament dispensing pathway 100 may be at least partially positioned outside the nozzle 80.
  • the inhaler includes a mechanism 200 for moving the canister 16 relative to the chamber 14 (see figures 5 to 10).
  • the mechanism 200 may be at least partially positioned in the chamber 14 to eject the canister 16 once it is empty or no longer required. A new canister may then be inserted into the chamber 14.
  • the mechanism 200 is configurable to move the canister 16 from a first, retracted, state (see figure 3) to a second, extended, state (see figure 4).
  • the lid 18 In the second extended state, the lid 18 may be in an open condition for permitting a user to grasp the canister 16.
  • the canister 16 In the second extended state, the canister 16 may protrude from the top 128 of the inhaler 10.
  • the mechanism 200 may be further configurable to move the canister 16 from the second, extended, state to the first, retracted, state.
  • the lid 18 In the first, retracted state the lid 18 may be in a closed condition to prevent or inhibit access to the canister 16.
  • the canister 16 In the first, retracted, state the canister 16 may be positioned entirely within the chamber 14.
  • the mechanism 200 may cause the canister 16 to move linearly from the first, retracted, state to the second, extended, state, or between the first and second states.
  • the mechanism 200 may cause the canister 16 to move in a direction generally parallel to a sidewall of the chamber 14 and / or the front and rear 120, 122 and / or first and second sides 124, 126 of the inhaler 10.
  • the mechanism 200 may cause the canister 16 to move generally linearly along an axis V defined by the valve stem 160.
  • the mechanism 200 may cause the canister 16 to slide from the first, retracted state to the second, extended, state, or between the first and second states.
  • the mechanism may cause the canister to pivot and I or rotate from the first, retracted state to the second, extended, state, or between the first and second states.
  • the valve stem 160 In the first, retracted, state the valve stem 160 may be received in the medicament dispensing pathway 100. In embodiments, the valve stem 160 may be positioned at a distance from the medicament dispensing pathway 100 in the first, retracted, state.
  • a locking member 500 (described in more detail below) may be movable to a locking condition to cause the mechanism to move to a fourth state. The canister 16 may remain in the same position when moving from the first state to the fourth state.
  • the valve stem 160 In the second, extended, state the valve stem 160 may be positioned at a distance from the medicament dispensing pathway 100. In embodiments, the valve stem 160 may be received in the medicament dispensing pathway 100 in the second, extended, state.
  • the mechanism 200 may be further configurable to move the canister 16 to a third, medicament dispensing, state.
  • the canister 16 In the third state the canister 16 may be positioned closer to the base 140 of the chamber 14 than in the first or second states.
  • the first state may be positioned between the second and third states.
  • the third state may be positioned between the first and second states.
  • the second state may be positioned between the first and third states.
  • the fourth state may be positioned between the first and third states.
  • valve stem 160 may be caused to move from a first, closed, condition to a second, dispensing, condition.
  • the mechanism 200 may cause the canister 16 to move from the first to the third state, or the second to the third state, or between the first and third or second and third states, in a similar way as described in relation to movement from the first to the second state, or between the first and second states.
  • the mechanism 200 may cause the canister 16 to move linearly from the first state to the third state, or between the first and third states.
  • the mechanism 200 may include a drive member 210.
  • the drive member 210 may be a motor, e.g., an electric motor.
  • the motor may be a brushless motor.
  • the drive member may be provided by other means without departing from the scope of the present disclosure.
  • the drive member 210 may have a rotor portion which defines an axis M about which the rotor portion rotates.
  • the axis M may be generally parallel to the axis V.
  • the axis M may be generally parallel to a main axis of the chamber 14.
  • the axis M may be inclined at an angle and I or generally orthogonal to the axis V and I or the main axis of the chamber 14 without departing from the scope of the present disclosure.
  • the axis M may be generally orthogonal to the pathway 50.
  • the axis M may be inclined at an angle to the pathway 50.
  • the axis M may be generally orthogonal to the pathway 50.
  • the drive member 210 may cause the mechanism 200 to move from the first to the second state, or between the first and second states.
  • the drive member 210 may cause the mechanism 200 to move from the first to the third or second to the third state, or between the first and third or second and third states.
  • the mechanism 200 may include a transmission member 220 for transmitting drive from the drive member 210 to the canister 16 (see figures 5 to 7).
  • the drive member 210 may be rotatably connected to the transmission member 220.
  • the rotor portion may be operably connected to the transmission member 220.
  • the transmission member 220 may include a transmission member base 224.
  • the base 224 may be generally circular in plan view. In embodiments, this may not be the case.
  • the base 224 may be other shapes such as ovular, square, rectangular or another polygonal shape without departing from the scope of the present disclosure.
  • the transmission member 220 may include a transmission member sidewall 230.
  • the sidewall 230 may extend upwardly away from the base 224.
  • the sidewall 230 may extend generally vertically upwardly away from the base 224, and I or generally orthogonally away from the base 224.
  • the sidewall 230 may extend at an angle away from the base 224, e.g., it may flare outwardly from the base 224 and I or it may taper as it extends away from the base 224.
  • the sidewall 230 may define a recess 240 in the transmission member 220. In use, the canister 16 may be received within the recess 240.
  • the transmission member 220 may include a protrusion (not shown).
  • the protrusion may be positioned on the sidewall 230.
  • the protrusion may be fixed in position.
  • the protrusion may be positioned in the recess 240.
  • the transmission member 220 may include a roller (not shown).
  • the roller may be positioned on the protrusion.
  • the roller may be permitted to rotate relative to the protrusion.
  • a plurality of protrusions may be provided. For example, two, or three or more protrusions may be provided without departing from the scope of the present disclosure.
  • One or more or all the protrusions may be provided with a roller. The function of the protrusions I rollers is described in more detail below.
  • the transmission member 220 may include a locking member cam surface 250.
  • the locking member cam surface 250 may be formed in the sidewall 230.
  • the locking member cam surface 250 may be provided by a recess I groove 252 formed in the sidewall 230.
  • a portion of a locking member 500 (described in more detail below) may be received in the recess I groove 252 or may abut against the locking member cam surface 250.
  • the locking member 500 may follow the cam surface 250 and, once the mechanism is in the first state, lock the canister 16 in the mechanism 200 to move the mechanism 200 to the fourth state.
  • the cam surface 250 may extend circumferentially around the transmission member 220 and may extend towards and I or away from the base 224 to cause the locking member 500 move to a first position to lock the canister 16 in position or a second position to permit release the canister 16 from the mechanism 200.
  • the cam surface 250 may include a first cam surface portion 254 which may be generally linear and may be a substantially constant distance from the base 224.
  • the first cam surface portion 254 may correspond to the second state of the mechanism 200.
  • the portion of the recess which forms the first cam surface portion 254 may have a substantially constant height.
  • the cam surface 250 may include a second cam surface portion 256 which may extend upwardly away from the base 224, e.g., generally linearly and I or inclined at an angle to the first cam surface portion 254.
  • the second cam surface portion 256 may be connected to and I or integrally formed with the first cam surface portion 254.
  • the portion of the recess which forms the second cam surface portion 256 may have a substantially constant height.
  • the cam surface 250 may include a third cam surface portion 258 which may extend towards the base 224, e.g., generally linearly and I or inclined at an angle to the first and I or second cam surface portions 254, 256.
  • the third cam surface portion 258 may be connected to and I or integrally formed with the second cam surface portion 256.
  • the portion of the recess 252 which forms the third cam surface portion 258 may extend towards a top of the transmission member 220, i.e., the recess I groove 252 may increase in width, as it extends away from the second cam surface portion 256.
  • the drive member 210, or the rotor portion may include a single gear 212.
  • the drive member 210, or the rotor portion may include more or fewer gears without departing from the scope of the present disclosure.
  • the rotor portion may include a gear and an additional gear. The additional gear may be positioned between the gear and a remainder of the drive member 210.
  • the gear 212 may be connectable to, or may mesh with, a second additional gear 214.
  • the second additional gear 214 may be larger than the gear 212.
  • the second additional gear 214 may be smaller or the same size as the gear 212.
  • the second additional gear may be operably connected to a first gear 216 via a shaft 218.
  • the second additional gear may be positioned between the first gear 216 and the drive member 210 and I or the additional gear.
  • no shaft 218 may be provided.
  • the gear 212, additional gear, second additional gear 214, first gear 216 and shaft 218 may be arranged in a generally vertical orientation.
  • the gear 212, additional gear, second additional gear 214, first gear 216 and shaft 218 may be positioned adjacent the chamber 14 and / or the rear side 122 of the inhaler 10. In embodiments this may not be the case.
  • the gear 212, additional gear, second additional gear 214, first gear 216 and shaft 218 may be arranged generally horizontally, or at an angle within the inhaler 10 without departing from the scope of the present disclosure.
  • the transmission member 220 may include a second gear 222 meshed with the first gear 216.
  • the second gear 222 may be integrally formed with the transmission member 220.
  • the second gear 222 may be formed separately and connected to the transmission member 220.
  • the second gear 222 may be at least partially circular.
  • the second gear 222 may form part of a circumference of a circle in plan view.
  • the second gear 222 may be larger than the first gear 216.
  • a ratio between the second gear 222 and the first gear 216 may be at least: 20:10; 30:10; 40:10; 50:10 or 60:10.
  • the ratio between the second gear 222 and the first gear 216 may be at most: 30:10; 40:10; 50:10; 60:10; 70:10; 80:10; 90:10 or 100:10.
  • the second gear 222 may be smaller than or the same size as the first gear 216.
  • the second gear 222 may extend, at least partially, around a periphery of the base 224. In embodiments, the second gear 222 may extend, at least partially, around a periphery of a sidewall or top of the transmission member 220. In embodiments, an additional second gear 222 may be provided around the periphery of the base or around a periphery of the sidewall or top of the transmission member 220 without departing from the scope of the present disclosure.
  • the mechanism 200 may include a cam member 300.
  • the mechanism may include a retaining member 600.
  • the mechanism may include a locking member 500.
  • the mechanism may include a cam member 300.
  • the cam member 300 may be received within the transmission member 220, or the recess 240 of the transmission member 220. In embodiments, this may not be the case.
  • the cam member 300 may be positioned, in use, outside the recess 240. In embodiments, the cam member 300 may be positioned, in use, adjacent the sidewall 230 of the transmission member 220.
  • the cam member 300 may be generally annular, or ring-shaped. In embodiments, the cam member 300 may be partially annular or partially ring-shaped. The cam member 300, in plan view, may be generally circular. In embodiments, the cam member 300 may be other shapes without departing from the scope of the present disclosure. For example, the cam member 300 may be ovular, square, rectangular or another polygonal shape in plan view without departing from the scope of the present disclosure.
  • the cam member 300 may have a cam member sidewall 310.
  • the cam member sidewall 310 may extend generally vertically. In embodiments, the sidewall 310 may extend generally parallel to the sidewall 230 of the transmission member 220. In embodiments, the sidewall 310 may taper inwardly and I or outwardly as it extends away from the base 140 of the chamber 14.
  • the sidewall 310 may define a passage 320. In use, the canister 16 may extend through the passage 320.
  • the cam member 300 may include a top 350 and a bottom 352.
  • the bottom 352 may be positioned closer to the medicament dispensing pathway 100 than the top 350.
  • the sidewall 310 may extend between the top 350 and the bottom 352.
  • the top 350 of the cam member 300 may be provided with one or more recesses 340.
  • the cam member 300 may define one or more recesses which extend downwardly from the top 350 of the cam member 300 into the sidewall 310, optionally towards the bottom 352 of the cam member 300.
  • the recesses 340 may be generally rectangular. One or more corners of the rectangular recesses 340 may have bevelled corners. In embodiments, this may not be the case.
  • the recesses may be arcuate or curvilinear or a polygonal shape without departing from the scope of the present disclosure.
  • the recesses may be shaped around, or to complement, one or more cam surfaces of the cam member 300.
  • the recesses 340 may be for receipt of a portion of the retaining member 600.
  • the cam member 300 may include a retaining portion 342 which extends across the recess 340 to retain the retaining member 600 in position relative to the cam member 300.
  • the retaining portion 342 may be formed as a strap-like portion which extends across the recess 340.
  • the sidewall 310 of the cam member 300 may include an internal surface 360.
  • the internal surface 360 may include one or more recesses 362.
  • the recesses 362 may extend downwardly from the top 350 of the cam member 300.
  • the recesses 362 may be for receipt of a portion of the retaining member 600.
  • the cam member 300 may include a cam surface 330.
  • the protrusion of the transmission member 220 may rest, or be received in or by, the cam surface 330.
  • the roller of the protrusion may rest on, or in, the came surface 330.
  • the cam surface 330 may be a slot and I or groove and I or recess provided in the cam member 300.
  • the cam surface 330 may be provided in, or positioned on, the sidewall 310 of the cam member 300.
  • the cam surface 330 may extend circumferentially around the cam member 300, at least partially.
  • the cam surface 330 may include a first cam surface portion 332.
  • the first cam surface portion 332 may extend upwardly from the bottom 352 of the cam member 300. In other words, the first cam surface portion 332 may terminate in a recess in the bottom 352 of the cam member 300.
  • the first cam surface portion 332 may extend generally helically upwardly from the bottom 352 of the cam member 300. In embodiments, the first cam surface portion 332 may extend generally circumferentially around the sidewall 310 of the cam member 300.
  • the cam surface 330 may include a second cam surface portion 334.
  • the second cam surface portion 334 may be generally parallel to the top 350 and I or bottom 352 of the cam member 300.
  • the second cam surface portion 334 may extend generally circumferentially around the sidewall 310 of the cam member 300.
  • the second cam surface portion 334 may extend generally helically upwardly from the bottom 352 of the cam member 300 and I or towards the top 350 of the cam member 300.
  • the second cam surface portion 334 may be connected to the first cam surface portion 332.
  • the cam surface 330 may include a third cam surface portion 336.
  • the third cam surface portion 336 may extend generally downwardly from the top 350 of the cam member 300. An end of the third cam surface portion 336 may be spaced from the top 350 of the cam member 300.
  • the third cam surface portion 336 may extend generally helically downwardly from the top 350 of the cam member 300.
  • the third cam surface portion 336 may extend generally helically downwardly from the top 350 of the cam member 300 at an angle less than, or shallower than, the first cam surface portion 332 extends generally upwardly from the bottom 352 of the cam member 300.
  • the third cam surface portion 336 may extend generally helically downwardly from the top 350 of the cam member 300 at an angle greater than, or deeper than, or the same as the first cam surface portion 332 extends generally upwardly from the bottom 352 of the cam member 300.
  • the third cam surface portion 336 may be connected to the second cam surface portion 334.
  • first and I or second and I or third cam surface portions 332, 334, 336 may extend in other ways without departing from the scope of the present disclosure, e.g., non-linearly or curvilinearly.
  • first and third cam surface portions may extend linearly away from the bottom 352 of the cam member 300 in the present embodiment.
  • the cam surface portions may extend parabolically, hyperbolically, exponentially or as a square or cubic function away from the bottom 352 or the top 350 of the cam member 300.
  • a plurality of cam surfaces 330 may be provided. In embodiments, two, or three or more cam surfaces 330 may be provided. In embodiments, a single cam surface 330 may be provided.
  • Rotational movement of the transmission member 220 may cause linear movement of the cam member 300 to cause the mechanism 200 to move between first and second positions.
  • Rotational movement of the transmission member 220 may cause linear movement of the cam member 300 to cause the mechanism 200 to move between second and third positions.
  • the linear movement may be generally vertical and I or between the top and bottom 128, 130 of the inhaler 10.
  • the drive member 210 may drive the transmission member 220 to cause the transmission member 220 to rotate. This, in turn, may cause the one or more protrusions to rotate. Because the protrusions are positioned in I received by the cam surfaces 330, movement of the protrusions may cause movement of the protrusions along I relative to the cam surfaces 330. Therefore, movement of the protrusions causes movement of the cam member 300 so the protrusions stay positioned in I received by the cam surfaces 330.
  • Movement of the protrusions along I relative to the first cam surface portion 332 so as to cause the cam member 300 to move downwardly may cause the mechanism 200 to move from the second state to the first state. Movement of the protrusions along I relative to the first cam surface portion 332 so as to cause the cam member 300 to move upwardly may cause the mechanism 200 to move from the first state to the second state.
  • the mechanism 200 may include a retaining member 600.
  • the retaining member 600 may retain the canister 16 relative to the mechanism 200.
  • the retaining member 600 may have a retaining member body 602.
  • the retaining member body 602 may be generally annular, or ring-shaped in plan view. In embodiments, the retaining member body 602 may be partially annular or partially ring-shaped. The retaining member body 602, in plan view, may be generally circular. In embodiments, the retaining member body 602 may be other shapes without departing from the scope of the present disclosure. For example, the retaining member body 602 may be ovular, square, rectangular or another polygonal shape in plan view without departing from the scope of the present disclosure.
  • the retaining member 600 may extend generally circumferentially around the canister 16, in use. In embodiments, the retaining member 600 may extend circumferentially around only a portion of the canister 16, in use. In embodiments, the retaining member 600 may not extend circumferentially around the canister 16.
  • the retaining member 600 in the present embodiment may be a collet. In embodiments, this may not be the case.
  • the retaining member 600 may include a plurality of retaining portions, or teeth, 610 for retaining the canister 16.
  • the retaining member 600 may include at least 3, 5, 7, 9, 10 or 12 retaining portions 610.
  • the retaining member 600 may include at most 13, 15, 17, 19 or 20 retaining portions 610.
  • the retaining portions 610 may extend generally upwardly away from the retaining member body 602.
  • the retaining portions 610 may extend generally orthogonally upwardly away from the retaining member body 602. In embodiments, the retaining portions 610 may extend at an angle away from the retaining member body 602.
  • the retaining portions 610 may be movable to a first condition in which the retaining portions 610 permit the canister 16 to move relative to the retaining member 600.
  • the retaining portions 610 may be movable to a second condition in which the retaining portions 610 retain the canister 16 relative to the retaining member 600.
  • the retaining portions 610 may be movable between the first and second conditions.
  • the retaining portions 610 may be biased to adopt the first condition. In embodiments, the retaining portions 610 may be biased to adopt the second condition.
  • the retaining portions 610 may include a canister retaining formation 612 which may extend over an end of the canister 16, in use, to retain the canister 16 relative to the retaining member 600 in the second condition.
  • the canister retaining formation 612 may define a generally arcuate or curvilinear surface which may be complementary to an outside surface of an end of the canister 16.
  • the retaining portions 610 may include a locking formation 614 for permitting the retaining portions 610 to be locked in a condition.
  • the condition may be the first condition. In embodiments, the condition may be the second condition.
  • the locking member 500 may be configured to abut the locking formation 614.
  • the retaining member 600 may be attached to the cam member 300 in use to retain the canister 16 relative to the cam member 300.
  • the retaining member 600 may include one or more attachment portions 620.
  • the attachment portion 620 may be a sprung clip or tooth. In embodiments, this may not be the case.
  • the attachment portion 620 may be part of a fastener or the like in embodiments.
  • the retaining member 600 may include two or three or more attachment portions 620. In embodiments, only a single attachment portion 620 may be provided.
  • the attachment portion 620 may extend generally downwardly away from the retaining member body 602.
  • the attachment portion 620 may extend generally orthogonally downwardly away from the retaining member body 602. In embodiments, the attachment portion 620 may extend at an angle away from the retaining member body 602.
  • the attachment portion 620 may be on a generally opposite side of the retaining member body 602 to the retaining portions 610.
  • the attachment portion 620 may extend generally linearly away from the retaining member body 602. In other words, the attachment portion, in side view, may be generally rectangular. In embodiments, the attachment portion 620 may be other shapes. For example, the attachment portion 620 may be generally square, triangular, or parallelogram shaped or any other polygonal shape in side view without departing from the scope of the present disclosure.
  • the attachment portion 620 may include an abutment 622.
  • the abutment 622 may extend in a direction generally outwardly from a remainder of the attachment portion 620 and the retaining member body 602.
  • the abutment 622 may include a portion which reduces in thickness as it extends along the attachment portion 620 away from the retaining member body 602.
  • the attachment portion may include an attachment formation 624 for attaching the retaining member 600 to the cam member 300.
  • the attachment formation 624 may extend generally inwardly towards the canister 16, in use.
  • the attachment portion 620 may be received at least partially, in use, by the recess 340 in the cam member 300.
  • the attachment portion 620 may at least partially extend between the recess 340 and the retaining portion 342 to enable the retaining member 600 to be attached to the cam member 300.
  • the attachment formation 624 may abut against the retaining portion 342 in use and inhibit separation of the cam member 300 and retaining member 600.
  • the abutment 622 may be received in the recess 340 when the retaining member 600 is attached to the cam member 300.
  • the retaining member 600 may include a locking member 500 for locking the retaining portions 612 in the second condition.
  • the locking member 500 may be configured to adopt a locking condition and unlocking condition. In the locking condition the locking member 500 may urge the retaining portions 612 to adopt the second condition. In the unlocking condition the locking member 500 may permit the retaining portions 612 to adopt the first condition.
  • the mechanism 200 may be configured such that, as the mechanism 200 moves from the first, retracted, position to the second, extended, position the locking member 500 changes from the locking to the unlocking condition.
  • the locking member 500 may be held in position relative to the retaining member 600 and / or the cam member 300 so that the locking member 500 effectively slides over the retaining member 600 as the retaining member 600 moves upwardly, from the first to the second position, for example and vice versa. This may permit the retaining portions 612 to move between the first and second conditions respectively.
  • the locking member 500 in use, may be substantially coaxial with the retaining member 600 and I or the cam member 300 and I or the transmission member 220. In embodiments the locking member may be parallel or inclined at an angle to the retaining member 600 and I or the cam member 300 and I or the transmission member 220 without departing from the scope of the present disclosure.
  • the locking member 500 may be a locking ring which may extend over the retaining member/ collet 600 to urge the retaining portions 612 into the second condition.
  • the locking member 500 may include a locking member body 520 which may be generally annular. In embodiments, the locking member body 520 may be any of the shapes described in respect of the retaining member 600.
  • the locking member 500 may include a locking member guide formation 530 which may extend downwardly from the locking member body 520.
  • the guide formation 530 of the locking member 500 may follow the locking member cam surface 250 as the mechanism 200 moves from the first, retracted, position to the second, extended, position.
  • the guide formation 530 may follow the first portion of the cam surface 254 and be in the unlocking condition, e.g., whilst the mechanism is in the second position and as the mechanism moves towards the first position.
  • the guide formation 530 may follow the second portion of the cam surface 256 and cause the locking member 500 to move to the locking condition, e.g., whilst the mechanism is in the first position. This may be a fourth state of the mechanism 200. The guide formation 530 may then follow the third portion of the cam surface 258 as the mechanism moves towards the third position. This may be to maintain the locking member 500 in a locking condition whilst medicament is dispensed from the canister 16.
  • Such a retaining member 600 may be advantageous in enabling the second, extended state, to be further from the first, retracted, state than if the retaining member 600 were not present. This may be advantageous in enabling a user to more easily grasp a canister 16 to be removed.
  • the canister 16 may be received entirely within the chamber 14.
  • the mechanism 200 may be in the first state.
  • a user may then receive a prompt via the screen 60 that the canister 16 needs to be replaced.
  • the user may then press the button 30 to cause the canister to be ejected from the inhaler 10, e.g., when the canister 16 may be empty or if the nozzle 80 may be required to be cleaned.
  • the inhaler may automatically cause the canister 16 to be ejected from the inhaler 10.
  • the controller 20 may send instructions to the drive member 210 to cause the drive member 210 to operate.
  • the controller 20 may send instructions to the drive member 210 to cause the drive member 210 to rotate. Operation of the drive member 210 may then cause the first gear 216 to rotate.
  • the protrusions may then follow the cam surface 330.
  • the protrusions may travel along the first and I or second portions 332, 334 of the cam surface 330 in a direction generally from the second portion 334 towards the first portion 332 of the cam surface 330.
  • Movement of the protrusions along the first and I or second portions 332, 334 of the cam surface 330 in a direction generally from the second portion 334 towards the first portion 332 of the cam surface 330 may then cause the cam member 300 to move upwardly which in turn may cause the retaining member 600 to move upwardly. Due to the canister 16 being retained by the retaining member 600, this may cause the canister 16 to move upwardly. Prior to this occurring, or concurrently, the controller 20 may cause the latch of the lid 18 to release to expose the opening of the chamber 14. A portion of the retaining member 600, and the canister 16, may then protrude through the opening of the chamber 14. The locking member 500 may have prior to the above occurring, or concurrently, moved from a locking to an unlocking condition, relative to the retaining member 600, to permit the retaining portions 612 to adopt the first condition. The canister 16 may then be removed from the inhaler 10.
  • the canister 16 may be received within the chamber 14.
  • the mechanism 200 may be in the first state.
  • a user may then receive a prompt via the screen 60 that the inhaler is in a dispensing mode and may inhale medicament.
  • the controller 20 may then use a sensor to determine whether a user is inhaling through the mouthpiece 40.
  • the sensor may be the spirometry sensor 1000. If a drop in pressure is detected the controller 20 may send instructions to the drive member 210 to cause the drive member 210 to rotate. Operation of the drive member 210 may then cause the first gear 216 to rotate. Due to the intermeshing of the first and second gears 216, 222, rotation of the first gear 216 may cause rotation of the second gear 222.
  • Rotation of the second gear 222 may then cause rotation of the transmission member 220 which in turn may cause rotation of the protrusions.
  • the protrusions may then follow the cam surface 330.
  • the protrusions may travel along the second and / or third portions 334, 336 of the cam surface 330 in a direction generally from the second portion 334 towards the third portion 336 of the cam surface 330. Movement of the protrusions along the second and / or third portions 334, 336 of the cam surface 330 in a direction generally from the second portion 334 towards the third portion 336 of the cam surface 330 may then cause the cam member 300 to move downwardly which in turn may cause the retaining member 600 to move downwardly.
  • FIG. 1 there is shown a second mechanism 200’.
  • the drive member 210’ and its connection to the transmission member 220’ may be substantially the same and so these will not be described again.
  • the transmission member 220’ may include the cam surface 330’ (shown in dashed lines in figure 13).
  • the sidewall 230’ may include the cam surface 330’.
  • the cam surface 330’ may be positioned within the recess 240’.
  • the cam surface 330’ may be positioned outside the recess 240’ on the sidewall 230’.
  • the cam surface 330’ may be a slot and I or groove and I or recess provided in the sidewall 230’.
  • the cam surface 330’ may extend generally helically around the sidewall 230’.
  • the cam surface 330’ may extend between the top and the base 224’ of the transmission member 220’.
  • the cam surface 330’ may be similar to the cam surfaces described in relation to the first embodiment.
  • a plurality of cam surfaces 330’ may be provided. The or each cam surface 330’ may be as described above and I or as described in respect of the first embodiment. Each of the plurality of cam surfaces 330’ may be positioned within the recess 240’.
  • the transmission member 220’ may include one or more ball bearings or bearings 2300’.
  • the ball bearings may rest on the base 224’ of the transmission member 220’. In use, the ball bearings may abut the main body 12’ of the inhaler 10’ and roll between the main body 12’ and the base 224’.
  • the retaining member 600’ may include a protrusion 640’, rather than the transmission member
  • the protrusion may rest on the cam surface 330’.
  • the inhaler 10’ and I or the protrusion 640’ may include a roller 642’.
  • the roller 642’ may be positioned on the protrusion 640’ and may be permitted to rotate relative to the protrusion 640’.
  • the roller 642’ may rest on the cam surface 330’.
  • the protrusion 640’ may be similar to the protrusions described in relation to the first embodiment.
  • the retaining member 600’ may include a plurality of protrusions 640’. Each of the plurality of protrusions 640’ may each include a respective roller 642’. In embodiments, one or more or less than all the protrusions 640’ may include a roller 642’.
  • Each of the respective rollers 642’ may be permitted to rotate relative to the respective protrusion 640’.
  • the or each respective roller 642’ may rest on the or each respective cam surface 330’.
  • the retaining member 600’ may not include any attachment portions.
  • the retaining member 600’ may include attachment portions as described in respect of the first embodiment.
  • the retaining member 600’ may include a locking member 500’ for locking the retaining portions 610’ in the second condition.
  • the locking member 500’ may be substantially annular and I or circular.
  • the locking member 500’ may be a locking ring which extends over the retaining member 600’ to urge the retaining portions 610’ into the second condition.
  • the retaining portions 610’ may, in use, extend around a generally opposite end of the canister 16’ to the retaining portions 610.
  • the retaining portions 610’ may extend around a portion of the canister 16’ which may be narrower than a remainder of the canister 16’. This may be advantageous in permitting the second state to be further from the first state than would otherwise be possible. This in turn may be advantageous in permitting a user to more easily grip the canister in the second state.
  • the locking member 500’ may include a base 540’ and a locking member sidewall 550’ which may extend upwardly from the base 540’.
  • the locking member sidewall 550’ may extend generally orthogonally upwardly from the base 540’. In embodiments, the sidewall 550’ may extend at an angle upwardly from the base 540’.
  • the inhaler 10’ may include a biasing member 560’ for biasing the retaining member 600’ to move away from the locking member 500’ to cause the locking member 500’ to abut the retaining portions 610’ of the retaining member 600’. This may be the locking position.
  • the biasing member 560’ may be a spring.
  • the inhaler 10’, or the mechanism 200’ may include a guide member 700’ (shown in figures 12 and 16).
  • the guide member 700’ may be for guiding the protrusion 640’, or the roller 642’, along the cam surface 330’.
  • the guide member 700’ may be received within the recess 240’ of the transmission member 220’.
  • the guide member 700’ in use, may stay in position as the transmission member 220’ rotates to cause the mechanism to move between first and second states.
  • the guide member 700’ may move as the transmission member 220’ rotates to cause the mechanism to move between first and second states.
  • the guide member 700’ may include a guide member base 724’.
  • the base 724’ may be generally circular in plan view.
  • the base 724’ may be other shapes such as ovular, square, rectangular or another polygonal shape without departing from the scope of the present disclosure.
  • the base 724’ may include an opening through which the canister 16’ may extend in use.
  • the guide member 700’ may include a guide member sidewall 730’.
  • the sidewall 730’ may extend upwardly away from the base 724’.
  • the sidewall 730’ may extend generally vertically upwardly away from the base 724’, and I or generally orthogonally away from the base 724’.
  • the sidewall 730’ may extend at an angle away from the base 724’, e.g., it may flare outwardly from the base 724’ and I or it may taper as it extends away from the base 724’.
  • the sidewall 730’ may define a recess I passage 740’ in the guide member 700’. In use, the canister 16’ may extend into / through the recess I passage 740’.
  • the guide member 700’ may include a top 726’.
  • An opening 728’ may be defined in the top 726’ for permitting access to the recess 740’.
  • the top 726’ may include a ridge 729’ which extends outwardly away from the opening 728’.
  • the guide member 700’ may include a slot 750’.
  • the sidewall 730’ may include the slot 750’.
  • the slot 750’ may extend between the base 724’ and the top 726’ of the guide member 700’.
  • the slot 750’ may extend generally vertically between the base 724’ and the top 726’. In embodiments, the slot 750’ may extend at an angle between the base 724’ and the top 726’.
  • the slot 750’ may have first and second respective ends 7500’, 7502’.
  • the first and I or second ends 7500’, 7502’ may be spaced from the base 724’ and I or the top 726’ of the guide member 700’.
  • the first end 7500’ may be positioned closer to the base 724’ than the second end 7502’.
  • a plurality of slots 750’ may be provided. In embodiments, two, three, four or more slots 750’ may be provided without departing from the scope of the present disclosure.
  • the or each slot 750’ may be as described above.
  • the protrusion 640’ may extend through the slot 750’.
  • the roller 642’ may be positioned, in use, adjacent an external surface of the sidewall 730’.
  • the roller 642’ may have a size / diameter which may be larger than a width of the slot 750’.
  • the roller 642’ may have a size I diameter which may be the same size as or smaller than a width of the slot 750’.
  • the terms "comprises” and “comprising” and variations thereof mean that the specified features, steps or integers are included. The terms are not to be interpreted to exclude the presence of other features, steps or components.
  • the invention may also broadly consist in the parts, elements, steps, examples and/or features referred to or indicated in the specification individually or collectively in any and all combinations of two or more said parts, elements, steps, examples and/or features. In particular, one or more features in any of the embodiments described herein may be combined with one or more features from any other embodiment(s) described herein.

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Inhalateur, comprenant : un corps principal ; une chambre pour la réception d'une cartouche contenant un médicament ; une voie de distribution dans laquelle un médicament peut être administré à un utilisateur ; une ouverture de voie de distribution en communication fluidique avec la voie de distribution à travers laquelle l'utilisateur peut inhaler le médicament ; une buse pour distribuer le médicament dans la voie de distribution, ladite buse comprenant une ouverture de buse à travers laquelle le médicament est distribué ; une voie de distribution de médicament pouvant être relié de manière fluidique à la cartouche reçue dans la chambre ; et un mécanisme pour déplacer la cartouche par rapport à la chambre ; le mécanisme pouvant être configuré pour déplacer la cartouche d'un premier état rétracté à un second état étendu.
PCT/GB2024/052469 2023-09-25 2024-09-25 Inhalateur Pending WO2025068692A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB2314684.8A GB2633855A (en) 2023-09-25 2023-09-25 An inhaler
GB2314684.8 2023-09-25

Publications (1)

Publication Number Publication Date
WO2025068692A1 true WO2025068692A1 (fr) 2025-04-03

Family

ID=88599152

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2024/052469 Pending WO2025068692A1 (fr) 2023-09-25 2024-09-25 Inhalateur

Country Status (2)

Country Link
GB (1) GB2633855A (fr)
WO (1) WO2025068692A1 (fr)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005113384A1 (fr) * 2004-04-30 2005-12-01 Tebro S.A. Dispositif de distribution de produit fluide
WO2018200655A1 (fr) * 2017-04-25 2018-11-01 3M Innovative Properties Company Inhalateur médical comprenant un mécanisme de neutralisation de verrouillage
US20200086069A1 (en) * 2015-07-20 2020-03-19 Pearl Therapeutics, Inc. Aerosol delivery systems
US20230060321A1 (en) * 2021-08-27 2023-03-02 Shanghai Sonmol Internet Technology Co., Ltd. Automatic detection trigger device for quantitative compressed administration aerosol

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8141550B2 (en) * 2006-08-01 2012-03-27 Trudell Medical International Dispensing device

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005113384A1 (fr) * 2004-04-30 2005-12-01 Tebro S.A. Dispositif de distribution de produit fluide
US20200086069A1 (en) * 2015-07-20 2020-03-19 Pearl Therapeutics, Inc. Aerosol delivery systems
WO2018200655A1 (fr) * 2017-04-25 2018-11-01 3M Innovative Properties Company Inhalateur médical comprenant un mécanisme de neutralisation de verrouillage
US20230060321A1 (en) * 2021-08-27 2023-03-02 Shanghai Sonmol Internet Technology Co., Ltd. Automatic detection trigger device for quantitative compressed administration aerosol

Also Published As

Publication number Publication date
GB2633855A (en) 2025-03-26
GB202314684D0 (en) 2023-11-08

Similar Documents

Publication Publication Date Title
KR100269060B1 (ko) 일체된 미터링 장치를 가진 약제 분말 카트리지 및 분말 약흡입기
EP1386630B1 (fr) Inhalateur de poudre
EP1381416B1 (fr) Dispositif d'inhalation
EP3131611B1 (fr) Inhalateur à capsule à charnière
EP0520440B1 (fr) Dispositif d'inhalation pour médicaments en poudre
AU2002255808A1 (en) Inhalation device and method
WO2005113043A1 (fr) Dispositif pour inhaler un medicament
CN114259632B (zh) 一种推扭式储库型粉雾剂装置
EP2731572B1 (fr) Améliorations portant sur des dispositifs d'administration
WO2025068692A1 (fr) Inhalateur
EP2731573A1 (fr) Améliorations relatives aux dispositifs de distribution
RU2533727C1 (ru) Ингалятор
WO2025068693A1 (fr) Inhalateur
EP3320936A1 (fr) Nouvelle roue de guidage pour des dispositifs d'inhalation
WO2025068695A1 (fr) Inhalateur
HK40014153A (en) A new guide gear for inhaler devices
HK1231422B (en) A hinged capsule inhaler
HK1061658B (en) Inhalation device

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 24786524

Country of ref document: EP

Kind code of ref document: A1