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WO2025059223A1 - Semelle intérieure de chaussure thérapeutique auto-assemblée avec distribution de principe actif - Google Patents

Semelle intérieure de chaussure thérapeutique auto-assemblée avec distribution de principe actif Download PDF

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Publication number
WO2025059223A1
WO2025059223A1 PCT/US2024/046265 US2024046265W WO2025059223A1 WO 2025059223 A1 WO2025059223 A1 WO 2025059223A1 US 2024046265 W US2024046265 W US 2024046265W WO 2025059223 A1 WO2025059223 A1 WO 2025059223A1
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WO
WIPO (PCT)
Prior art keywords
insole
active ingredient
polymer material
foot
vitamin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/US2024/046265
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English (en)
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WO2025059223A9 (fr
Inventor
Daniel Lawrence KLOOS
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
American Custom Technologies LLC
Original Assignee
American Custom Technologies LLC
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Filing date
Publication date
Application filed by American Custom Technologies LLC filed Critical American Custom Technologies LLC
Publication of WO2025059223A1 publication Critical patent/WO2025059223A1/fr
Publication of WO2025059223A9 publication Critical patent/WO2025059223A9/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A43—FOOTWEAR
    • A43B—CHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
    • A43B17/00—Insoles for insertion, e.g. footbeds or inlays, for attachment to the shoe after the upper has been joined
    • A43B17/003—Insoles for insertion, e.g. footbeds or inlays, for attachment to the shoe after the upper has been joined characterised by the material
    • A—HUMAN NECESSITIES
    • A43—FOOTWEAR
    • A43B—CHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
    • A43B1/00—Footwear characterised by the material
    • A—HUMAN NECESSITIES
    • A43—FOOTWEAR
    • A43B—CHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
    • A43B7/00—Footwear with health or hygienic arrangements
    • A43B7/14—Footwear with health or hygienic arrangements with foot-supporting parts
    • A43B7/1405—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form
    • A—HUMAN NECESSITIES
    • A43—FOOTWEAR
    • A43B—CHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
    • A43B7/00—Footwear with health or hygienic arrangements
    • A43B7/14—Footwear with health or hygienic arrangements with foot-supporting parts
    • A43B7/1405—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form
    • A43B7/1455—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form with special properties
    • A—HUMAN NECESSITIES
    • A43—FOOTWEAR
    • A43B—CHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
    • A43B7/00—Footwear with health or hygienic arrangements
    • A43B7/14—Footwear with health or hygienic arrangements with foot-supporting parts
    • A43B7/1405—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form
    • A43B7/1455—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form with special properties
    • A43B7/1463—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form with special properties with removable pads to allow custom fit
    • A—HUMAN NECESSITIES
    • A43—FOOTWEAR
    • A43B—CHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
    • A43B7/00—Footwear with health or hygienic arrangements
    • A43B7/14—Footwear with health or hygienic arrangements with foot-supporting parts
    • A43B7/1405—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form
    • A43B7/1455—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form with special properties
    • A43B7/1464—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form with special properties with adjustable pads to allow custom fit
    • A—HUMAN NECESSITIES
    • A43—FOOTWEAR
    • A43B—CHARACTERISTIC FEATURES OF FOOTWEAR; PARTS OF FOOTWEAR
    • A43B7/00—Footwear with health or hygienic arrangements
    • A43B7/14—Footwear with health or hygienic arrangements with foot-supporting parts
    • A43B7/1405—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form
    • A43B7/1455—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form with special properties
    • A43B7/147—Footwear with health or hygienic arrangements with foot-supporting parts with pads or holes on one or more locations, or having an anatomical or curved form with special properties for sick or disabled persons, e.g. persons having osteoarthritis or diabetes

Definitions

  • the present disclosure relates to shoe insoles, and more particularly to a therapeutic shoe insole with active ingredient deliver ⁇ ' capabilities.
  • Shoe insoles have long been used as a means to address foot-related issues and enhance comfort.
  • Traditional insoles typically provide cushioning and support, aiming to redistribute pressure and improve foot alignment.
  • these conventional insoles often fall short in addressing specific medical needs or providing targeted therapeutic benefits.
  • an orthotic insertable in footwear generally in the shape of a shoe.
  • the orthotic includes a midfoot portion having an apex and forming an arch height, and a heel portion aft of the midfoot portion, the heel portion being generally hook-shaped.
  • the present disclosure provides a therapeutic shoe insole designed with a unique self-assembling structure.
  • This innovative design allows for the incorporation and delivery' of active ingredients, offering potential therapeutic benefits to the wearer.
  • the insole's structure is formed from co-injected planar polymer materials, which can be customized to suit the specific needs of the user. This customization may take into account factors such as the user's foot size, weight, age, activity level, and specific foot-related conditions.
  • the insole is designed to provide mechanical support and comfort.
  • the insole's structure, thickness, and rigidity can be customized to provide optimal support and pressure distribution, potentially improving foot alignment and reducing discomfort.
  • the therapeutic shoe insole disclosed herein offers a comprehensive solution for enhancing foot health and comfort.
  • the insole may provide an effective means of managing a wide range of foot-related issues.
  • the insole 100 comprises a midfoot portion 110 with an apex forming an arch height.
  • the midfoot portion 110 is designed to support the arch of the foot, helping to distribute pressure more evenly and align the foot in a more natural position.
  • the arch height can be customized to suit the specific needs of the user, taking into account factors such as the user's foot size, weight, age, activity level, and specific foot-related conditions.
  • the insole 100 may be made of memory foam material.
  • Memory foam is a type of polyurethane foam that is known for its viscoelastic properties, allow ing it to conform to the shape of the foot and provide customized support and cushioning. This material may offer a soft, comfortable feel, enhancing the overall comfort of the insole 100.
  • the memory foam material may also provide excellent shock absorption, reducing the impact on the feet and joints during walking, running, or other activities.
  • the insole 100 may be made of gel material.
  • Gel is a soft, flexible material that can adapt to the foot's movements, providing superior cushioning and pressure relief. Some gel materials may also offer a cooling sensation, reducing heat and sweat build-up within the shoe. This can be particularly beneficial for individuals who engage in high-impact activities or who experience excessive foot sweating.
  • the insole 100 may also include active ingredients micro-injected into the pores of the polymer material.
  • active ingredients may include various medicinal or therapeutic compounds, such as analgesics, antiinflammatories, or antimicrobials, among others.
  • the micro-injection of these active ingredients allows for a controlled and sustained release of the compounds, potentially providing targeted treatment for various foot-related conditions.
  • the specific active ingredients incorporated into the insole 100 may be selected based on the specific needs of the user, taking into account factors such as the user's foot condition, age, weight, activity level, and other relevant factors.
  • the insole 100 may further include a metatarsal pad 150 generally placed near a forward end of the insole.
  • the metatarsal pad 150 is designed to provide extra padding underneath the ball of the foot, helping to alleviate pressure and distribute weight more evenly across the foot. This can be particularly beneficial for individuals with conditions such as metatarsalgia or Morton's neuroma, which can cause pain and discomfort in the ball of the foot.
  • the metatarsal pad 150 may be made from a variety of materials, including but not limited to, foam, gel, or air-cushioned materials, depending on the desired level of cushioning and support.
  • the insole 100 may include a heel posting 160 generally connected underneath the center portion 110 at the heel end.
  • the heel posting 160 is designed to provide additional support and stability to the heel area, helping to control foot motion and alignment during walking or running.
  • the heel posting 160 may be made from a variety of materials, such as hard plastic, rubber, or other durable materials, depending on the desired level of support and rigidity.
  • the insole 100 may include electronic accessories for Pulsed Electro-Magnetic Frequency (PEMF) delivery.
  • PEMF is a type of therapy that uses electromagnetic fields to improve health and well-being.
  • PEMF may be used to enhance the therapeutic benefits of the insole, potentially helping to reduce pain, inflammation, and other foot-related conditions.
  • the electronic accessories for PEMF delivery' may be integrated into the insole 100 in a manner that does not interfere with the comfort or functionality of the insole.
  • methyl salicylate in the insole 100 may' offer potential analgesic and anti-inflammatory properties. When applied topically, methyl salicylate may help alleviate minor aches and pains associated with various foot conditions. The compound may work by increasing blood flow to the affected area and providing a mild cooling sensation, which may help reduce discomfort and promote healing.
  • the methyl salicylate may be combined with other active ingredients to enhance its therapeutic effects.
  • it may be used in conjunction with menthol or camphor to create a synergistic cooling and pain-relieving effect.
  • the specific formulation and concentration of methyl salicylate used in the insole 100 may be tailored to suit the individual needs of the user and the intended therapeutic outcomes.
  • the controlled release of methyl salicylate from the pores of the polymer material may allow for sustained delivery of the active ingredient over an extended period. This sustained release may provide ongoing therapeutic benefits throughout the day, potentially offering relief during prolonged periods of standing, walking, or other activities that may cause foot discomfort.
  • the methyl salicylate may be encapsulated within microspheres before being micro-injected into the polymer material. This encapsulation process may help protect the active ingredient from degradation and allow for even more precise control over its release rate. The size and composition of these microspheres may be adjusted to achieve the desired release profile, ensuring optimal therapeutic efficacy.
  • methyl salicylate may be particularly beneficial for users experiencing muscle soreness, joint pain, or mild arthritis in the feet.
  • the compound's potential ability to penetrate the skin and reach underlying tissues may make it an effective option for addressing these types of conditions.
  • the concentration of methyl salicylate used in the insole 100 may be adjustable based on user preferences and specific foot care needs. For instance, a higher concentration may be used for individuals seeking more intense pain relief, while a lower concentration may be suitable for those looking for milder, long-term comfort.
  • the concentration of capsaicin used in the insole 100 may be adjustable based on user preferences and specific foot care needs. For instance, a higher concentration may be used for individuals seeking more intense pain relief, while a lower concentration may be suitable for those looking for milder, long-term comfort.
  • the insole 100 may be designed with specific zones that contain higher concentrations of capsaicin. These zones may correspond to common pressure points or areas prone to pain, such as the heel, arch, or metatarsal area. This targeted approach may allow for more effective pain relief in problem areas while minimizing potential irritation in less sensitive regions of the foot.
  • the insole 100 may also feature a protective layer or coating to prevent direct contact between the capsaicin-infused material and the user's skin. This may help reduce the risk of skin irritation while still allowing for the gradual release and absorption of the active ingredient.
  • the insole 100 may incorporate camphor as one of the active ingredients micro-injected into the pores of the polymer material.
  • camphor is a naturally occurring compound derived from the wood of the camphor tree that may provide various therapeutic benefits when used in the context of foot care.
  • camphor in the insole 100 may offer potential analgesic, antiinflammatory, and antimicrobial properties. When applied topically, camphor may help alleviate minor aches and pains associated with various foot conditions. The compound may work by creating a cooling sensation and increasing local blood flow, which may help reduce discomfort and promote healing.
  • the camphor may be combined with other active ingredients to enhance its therapeutic effects.
  • it may be used in conjunction with menthol or methyl salicylate to create a synergistic cooling and pain-relieving effect.
  • the specific formulation and concentration of camphor used in the insole 100 may be tailored to suit the individual needs of the user and the intended therapeutic outcomes.
  • the controlled release of camphor from the pores of the polymer material may allow for sustained delivery of the active ingredient over an extended period.
  • This sustained release may provide ongoing therapeutic benefits throughout the day, potentially offering relief during prolonged periods of standing, walking, or other activities that may cause foot discomfort.
  • the camphor may be encapsulated within microspheres before being micro-injected into the polymer material. This encapsulation process may help protect the active ingredient from degradation and allow for even more precise control over its release rate. The size and composition of these microspheres may be adjusted to achieve the desired release profile, ensuring optimal therapeutic efficacy.
  • camphor into the insole 100 may be particularly beneficial for users experiencing muscle sorenessjoint pain, or fungal infections of the feet.
  • the compound's potential ability to penetrate the skin and reach underlying tissues may make it an effective option for addressing these types of conditions.
  • the concentration of camphor used in the insole 100 may be adjustable based on user preferences and specific foot care needs. For instance, a higher concentration may be used for individuals seeking more intense pain relief or antimicrobial effects, while a lower concentration may be suitable for those looking for milder, long-term comfort.
  • camphor in the insole 100 may also contribute to the overall sensory experience of wearing the insole.
  • the compound's characteristic cooling sensation and aromatic scent may provide a refreshing feeling that some users may find appealing.
  • the formulation may be adjusted to minimize or eliminate this sensation and scent for users who prefer a more neutral experience.
  • the insole 100 may be designed with replaceable camphor- infused components. This may allow users to replace or replenish the active ingredient as needed, extending the therapeutic lifespan of the insole. These replaceable components may come in various strengths or formulations, allowing users to customize their treatment over time.
  • the insole 100 may also feature a protective layer or coating to prevent direct contact betw een the camphor-infused material and the user's skin. This may help reduce the risk of skin irritation while still allowing for the gradual release and absorption of the active ingredient.
  • the insole 100 may incorporate menthol as one of the active ingredients micro-injected into the pores of the polymer material.
  • Menthol is a naturally occurring organic compound derived from peppermint or other mint oils that may provide various therapeutic benefits w hen used in the context of foot care.
  • the menthol may be combined with other active ingredients to enhance its therapeutic effects.
  • it may be used in conjunction with camphor or methyl salicylate to create a synergistic cooling and pain-relieving effect.
  • the specific formulation and concentration of menthol used in the insole 100 may be tailored to suit the individual needs of the user and the intended therapeutic outcomes.
  • the controlled release of menthol from the pores of the polymer material may allow for sustained delivery' of the active ingredient over an extended period. This sustained release may provide ongoing therapeutic benefits throughout the day, potentially offering relief during prolonged periods of standing, walking, or other activities that may cause foot discomfort.
  • the menthol may be encapsulated within microspheres before being micro-injected into the polymer material. This encapsulation process may help protect the active ingredient from degradation and allow for even more precise control over its release rate. The size and composition of these microspheres may be adjusted to achieve the desired release profile, ensuring optimal therapeutic efficacy.
  • menthol may be particularly beneficial for users experiencing foot fatigue, muscle soreness, or general discomfort.
  • the compound's potential ability to provide a cooling sensation and mild pain relief may make it an effective option for addressing these types of conditions.
  • the concentration of menthol used in the insole 100 may be adjustable based on user preferences and specific foot care needs. For instance, a higher concentration may be used for individuals seeking more intense cooling relief, while a lower concentration may be suitable for those looking for milder, long-term comfort.
  • the use of menthol in the insole 100 may also contribute to the overall sensory experience of wearing the insole.
  • the compound's characteristic cooling sensation and minty aroma may provide a refreshing feeling that some users may find appealing.
  • the formulation may be adjusted to minimize or eliminate this sensation and scent for users who prefer a more neutral experience.
  • the insole 100 may incorporate a gradual release mechanism for the menthol. This may involve using different polymer materials or pore sizes in various regions of the insole, allowing for a controlled release of the active ingredient over time. For example, the heel and ball of the foot areas may have a higher concentration or faster release rate of menthol, targeting areas that often experience more pressure and discomfort.
  • the insole 100 may also feature a multi-layer design that incorporates menthol in specific layers. For instance, a layer closer to the foot may contain a lower concentration of menthol for initial, mild cooling relief, while deeper layers may contain higher concentrations for sustained, long-term therapeutic effects.
  • the insole 100 may be designed with replaceable menthol - infused components. This may allow users to replace or replenish the active ingredient as needed, extending the therapeutic lifespan of the insole. These replaceable components may come in various strengths or formulations, allowing users to customize their treatment over time.
  • the insole 100 may also incorporate technology to enhance the effectiveness of menthol delivery.
  • it may include pressure-activated release mechanisms that increase the release of menthol in response to the user's body weight or movement. This could provide targeted relief during periods of increased activity or when standing for long periods.
  • the insole 100 may be designed with specific zones that contain higher concentrations of menthol. These zones may correspond to common pressure points or areas prone to excessive sweating, such as the ball of the foot or the arch area. This targeted approach may allow for more effective cooling and deodorizing effects in problem areas while minimizing potential irritation in less sensitive regions of the foot.
  • the insole 100 may also feature a protective layer or coating to prevent direct contact between the menthol-infused material and the user's skin. This may help reduce the risk of skin irritation while still allowing for the gradual release and absorption of the active ingredient.
  • the insole 100 may incorporate a combination of menthol and warming agents. This dual-action approach may provide immediate cooling relief followed by a warming sensation, potentially enhancing blood circulation and promoting overall foot comfort. The balance between these components may be adjusted to suit different user preferences and therapeutic needs.
  • the use of menthol in the insole 100 may also be combined with other therapeutic features, such as massaging textures or aromatherapy elements. This multi-modal approach to foot care may offer a more comprehensive solution for users dealing with various foot-related issues.
  • the insole 100 may incorporate a time-release mechanism for the menthol. This may involve encapsulating the menthol in different types of microspheres that dissolve at varying rates, allowing for a more controlled and prolonged release of the active ingredient throughout the day.
  • the insole 100 may also feature a moisture-wicking layer infused with menthol. This combination may help keep the feet dry while simultaneously providing a cooling sensation, potentially enhancing comfort and reducing the risk of fungal infections.
  • the menthol-infused insole 100 may be designed with different concentrations for various types of footwear or activities. For example, a higher concentration may be used for athletic shoes to provide more intense cooling during physical activity, while a lower concentration may be used for everyday shoes to provide mild, all-day comfort.
  • the insole 100 may also incorporate a temperature-responsive polymer that releases more menthol as the foot temperature increases.
  • This smart-release mechanism may provide adaptive cooling that responds to the user's activity level and environmental conditions.
  • the insole 100 may also incorporate technology to enhance the effectiveness of eucalyptus oil delivery.
  • it may include moisture-activated release mechanisms that increase the release of eucalyptus oil in response to foot perspiration. This could provide targeted protection during periods of increased sweating or in humid conditions.
  • the insole 100 may also incorporate a temperature-responsive polymer that releases more urea as the foot temperature increases.
  • This smart-release mechanism may provide adaptive moisturization that responds to the user's activity level and environmental conditions.
  • vitamin A in the insole 100 may offer potential skin-renewing, antioxidant, and moisturizing properties. When applied topically, vitamin A may help promote cell turnover and collagen production in the skin of the feet, which may be particularly beneficial for individuals with rough, dry, or aging skin. The compound may also work to protect the skin from environmental damage and improve overall skin texture and appearance.
  • the controlled release of vitamin A from the pores of the polymer material may allow for sustained delivery of the active ingredient over an extended period. This sustained release may provide ongoing therapeutic benefits throughout the day, potentially offering continuous skin-renewing and protective effects.
  • the insole 100 may also feature a protective layer or coating to prevent direct contact between the vitamin A-infused material and the user's skin. This may help reduce the risk of skin irritation while still allowing for the gradual release and absorption of the active ingredient.
  • the insole 100 may incorporate a time-release mechanism for the vitamin A. This may involve encapsulating the vitamin A in different types of microspheres that dissolve at varying rates, allowing for a more controlled and prolonged release of the active ingredient throughout the day.
  • the insole 100 may also feature a textured surface infused with vitamin A. This design may provide a mild exfoliating effect while simultaneously delivering the skinrenewing benefits of vitamin A, potentially enhancing skin texture and overall foot comfort.
  • the vitamin E may be combined with other active ingredients to enhance its therapeutic effects.
  • it may be used in conjunction with vitamin C or other antioxidants to create a synergistic protective effect.
  • the specific formulation and concentration of vitamin E used in the insole 100 may be tailored to suit the individual needs of the user and the intended therapeutic outcomes.
  • the vitamin E may be encapsulated within microspheres before being micro-injected into the polymer material. This encapsulation process may help protect the active ingredient from degradation and allow for even more precise control over its release rate. The size and composition of these microspheres may be adjusted to achieve the desired release profile, ensuring optimal therapeutic efficacy.
  • vitamin E may be particularly beneficial for users experiencing dry, cracked skin, or those seeking additional protection against environmental damage to their feet.
  • the compound's potential ability to improve skin barrier function and provide antioxidant protection may make it an effective option for addressing these types of conditions.
  • the concentration of vitamin E used in the insole 100 may be adjustable based on user preferences and specific foot care needs. For instance, a higher concentration may be used for individuals seeking more intense antioxidant protection, while a lower concentration may be suitable for those looking for milder, long-term skin maintenance.
  • the insole 100 may be designed with specific zones that contain higher concentrations of vitamin E. These zones may correspond to areas prone to dryness or increased friction, such as the heel or ball of the foot. This targeted approach may allow for more effective antioxidant and moisturizing effects in problem areas while minimizing potential overexposure in less sensitive regions of the foot.
  • the insole 100 may also feature a protective layer or coating to prevent direct contact between the vitamin E-infused material and the user's skin. This may help reduce the risk of skin irritation while still allowing for the gradual release and absorption of the active ingredient.
  • the insole 100 may incorporate a time-release mechanism for the vitamin E. This may involve encapsulating the vitamin E in different ty pes of microspheres that dissolve at varying rates, allowing for a more controlled and prolonged release of the active ingredient throughout the day.
  • the vitamin E-infused insole 100 may be designed with different concentrations for various types of footwear or activities. For example, a higher concentration may be used for athletic shoes to provide more intense antioxidant protection during physical activity, while a lower concentration may be used for everyday- shoes to provide mild, all-day skin maintenance.
  • the insole 100 may also incorporate an oxy gen-barrier polymer that helps stabilize the vitamin E.
  • This protective mechanism may 7 help preserve the efficacy of the vitamin E, which is known to be sensitive to oxidation, ensuring consistent therapeutic benefits over time.
  • the insole 100 may also feature a textured surface infused with vitamin E. This design may provide a mild massaging effect while simultaneously delivering the antioxidant benefits of vitamin E, potentially enhancing blood circulation and overall foot comfort.
  • the vitamin E-infused insole 100 may be designed with a color-changing indicator that shows when the vitamin E is depleted. This feature may help users know 7 when it's time to replace or replenish the active ingredient, ensuring consistent therapeutic benefits.
  • vitamin E in the insole 100 may also be combined with UV- protective technology. By incorporating UV-absorbing compounds, this approach may enhance the protective effects of vitamin E and provide broader defense against sun damage to the feet, potentially offering additional foot skin health benefits for users w ho frequently wear open shoes or engage in outdoor activities.
  • the insole 100 may incorporate combinations of methyl salicylate, capsaicin, camphor, menthol, eucalyptus oil, urea, vitamin A, and vitamin E as active ingredients micro-injected into the pores of the polymer material. These combinations may offer synergistic effects, potentially enhancing the overall therapeutic benefits of the insole.
  • the insole 100 may 7 feature different zones with specific combinations of active ingredients tailored to address various foot care needs.
  • a heel zone may incorporate a blend of methyl salicylate and menthol for pain relief and cooling effects
  • a midfoot zone may combine urea and vitamin E for moisturizing and antioxidant protection.
  • the insole 100 may utilize a layered approach to combine active ingredients.
  • a surface layer may contain a mixture of camphor and eucalyptus oil for immediate antimicrobial and cooling effects, while deeper layers may incorporate slower-releasing combinations of vitamin A and vitamin E for long-term skin health benefits.
  • the insole 100 may also feature customizable combinations of active ingredients based on user preferences and specific foot care needs. This may allow users to select combinations that target their particular concerns, such as pain relief, moisture control, or skin renewal.
  • the insole 100 may incorporate time-release mechanisms for different combinations of active ingredients. This may involve encapsulating various combinations in microspheres with different dissolution rates, potentially providing a sequence of therapeutic effects throughout the day.
  • the insole 100 may also utilize temperature-responsive polymers to control the release of different active ingredient combinations.
  • a combination of capsaicin and menthol may be released in response to increased foot temperature during physical activity, potentially providing enhanced pain relief and cooling effects when needed most.
  • the insole 100 may feature a gradient distribution of active ingredient combinations across its surface. This may allow for a gradual transition between different therapeutic effects, potentially providing a more comprehensive and nuanced approach to foot care.
  • the insole 100 may also incorporate technology to enhance the penetration and efficacy of active ingredient combinations. For instance, it may utilize iontophoresis to improve the delivery of ionic compounds like methyl salicylate, potentially enhancing their therapeutic effects when combined with other active ingredients.
  • the insole 100 may feature replaceable modules containing different combinations of active ingredients. This may allow users to customize their foot care regimen over time, adapting to changing needs or seasonal variations in foot health concerns.
  • the insole 100 may also utilize pH-responsive polymers to control the release of different active ingredient combinations. This may allow for targeted delivery of specific combinations based on the pH environment of the foot, potentially optimizing the efficacy of each active ingredient.
  • the insole 100 may incorporate cyclodextrin complexes to improve the stability and controlled release of volatile active ingredients like menthol and eucalyptus oil when combined with other compounds. This may help maintain the therapeutic effects of these combinations over extended periods.
  • the insole 100 may also feature a multi-phase release system for active ingredient combinations.
  • an initial phase may release a combination of cooling agents like menthol and camphor, followed by a secondary phase releasing moisturizing agents like urea and vitamin E, potentially providing comprehensive foot care throughout the day.
  • the insole 100 may utilize nanotechnology to enhance the delivery' and efficacy of active ingredient combinations.
  • Nanocarriers may be used to encapsulate and transport combinations of hydrophilic and hydrophobic compounds, potentially improving their bioavailability and therapeutic effects.
  • the insole 100 may also incorporate biomimetic materials that respond to mechanical stress to release specific combinations of active ingredients. For instance, areas of high pressure may trigger the release of pain-relieving combinations like methyl salicylate and capsaicin, potentially providing targeted relief during physical activity.
  • the insole 100 may feature a combination of active ingredients designed to create a protective microenvironment for the foot. This may involve blending antimicrobial agents like eucalyptus oil with moisturizing compounds like urea, potentially creating a barrier against infection while maintaining skin health.
  • the insole 100 may also utilize photocatalytic materials to enhance the effects of certain active ingredient combinations. For example, exposure to light may activate a combination of vitamin A and vitamin E, potentially providing enhanced antioxidant protection during outdoor activities.
  • the insole 100 may incorporate combinations of active ingredients designed to work synergistically with the body's natural circadian rhythms. For instance, a combination of stimulating ingredients like capsaicin may be released during the day, while soothing combinations including menthol may be emphasized at night.
  • the insole 100 may also feature combinations of active ingredients that respond to changes in the ionic environment of the foot. This may allow for adaptive release of therapeutic compounds based on factors like sweat composition, potentially providing personalized foot care throughout the day.
  • the insole 100 may utilize combinations of active ingredients encapsulated in liposomes or other lipid-based carriers. This may allow for improved penetration of both hydrophilic and hydrophobic compounds through the skin barrier, potentially enhancing the overall therapeutic efficacy of the combinations.
  • the insole 100 may also incorporate smart hydrogel systems that respond to multiple stimuli to release different combinations of active ingredients. These systems may react to changes in temperature, pH, and mechanical stress, potentially providing a highly adaptive and responsive approach to foot care.
  • the insole 100 may incorporate aluminum chloride hexahydrate-based antiperspirants as one of the active ingredients micro-injected into the pores of the polymer material.
  • Aluminum chloride hexahydrate is a compound known for its effectiveness in reducing excessive sweating, which may provide significant benefits in the context of foot care.
  • aluminum chloride hexahydrate-based antiperspirants in the insole 100 may offer potential sweat-reducing and odor-controlling properties.
  • aluminum chloride hexahydrate may help reduce perspiration by temporarily blocking sweat glands. This may be particularly beneficial for individuals who experience hyperhidrosis or excessive sweating of the feet.
  • the aluminum chloride hexahy drate may be combined with other active ingredients to enhance its therapeutic effects.
  • it may be used in conjunction with antimicrobial agents like eucalyptus oil to create a synergistic effect in controlling foot odor.
  • antimicrobial agents like eucalyptus oil to create a synergistic effect in controlling foot odor.
  • the specific formulation and concentration of aluminum chloride hexahydrate used in the insole 100 may be tailored to suit the individual needs of the user and the intended therapeutic outcomes.
  • the insole 100 may be designed with specific zones that contain higher concentrations of aluminum zirconium tetrachlorohydrex gly. These zones may correspond to areas prone to excessive sweating, such as the ball of the foot or the arch. This targeted approach may allow for more effective sweat control in problem areas while minimizing potential irritation in less sensitive regions of the foot.
  • the insole 100 may incorporate a time-release mechanism for the aluminum zirconium tetrachlorohydrex gly. This may involve encapsulating the antiperspirant in different types of microspheres that dissolve at varying rates, allowing for a more controlled and prolonged release of the active ingredient throughout the day.
  • the insole 100 may also feature a moisture-wi eking layer infused with aluminum zirconium tetrachlorohydrex gly. This combination may help keep the feet dry by both reducing sweat production and absorbing excess moisture, potentially enhancing comfort and reducing the risk of skin maceration and fungal infections.
  • the aluminum zirconium tetrachlorohydrex gly- infused insole 100 may be designed with different concentrations for various types of footwear or activities. For example, a higher concentration may be used for athletic shoes to provide more intense sweat control during physical activity 7 , while a lower concentration may be used for everyday shoes to provide mild, all-day perspiration management.
  • the insole 100 may also incorporate pH-balancing technology to work in conjunction with the aluminum zirconium tetrachlorohydrex gly. This may help maintain an optimal pH level on the surface of the foot, potentially enhancing the effectiveness of the antiperspirant while minimizing the risk of skin irritation.
  • the aluminum zirconium tetrachlorohydrex gly in the insole 100 may be combined with natural plant extracts known for their astringent properties, such as witch hazel or sage. This combination may provide enhanced sweat-reducing effects while offering additional skin-soothing benefits.
  • the insole 100 may also feature a textured surface infused with aluminum zirconium tetrachlorohydrex gly. This design may provide a mild exfoliating effect while simultaneously delivering the antiperspirant benefits, potentially enhancing its effectiveness by removing dead skin cells that can block sweat glands.
  • the aluminum zirconium tetrachlorohydrex gly-infused insole 100 may be designed with a color-changing indicator that shows when the antiperspirant is depleted. This feature may help users know when it's time to replace or replenish the active ingredient, ensuring consistent sweat control benefits.
  • Foot insoles and orthotics play a vital role in managing a wide range of foot conditions and improving overall foot health.
  • the data and real-world applications highlight the effectiveness of different types of insoles and orthotics in reducing pain, improving function, and enhancing quality of life for individuals with various foot-related issues. Whether used for general comfort, sports performance, or specific medical conditions, foot insoles and orthotics offer a valuable solution for maintaining foot health and preventing injuries.
  • the insole 100 may be modified in thickness to fit inside prescription orthotics, providing a customizable solution that accommodates medical needs without compromising the effectiveness of the prescribed orthotic device. This modification allows for a seamless integration of the therapeutic benefits of the insole with the structural support provided by the orthotic.
  • the insole 100 features variable durometer ratings, which can be adjusted to enhance comfort and provide therapeutic benefits tailored to the user's specific needs. This variability in firmness allows the insole to cater to different levels of cushioning and support required by users, ranging from softer insoles for enhanced comfort to firmer insoles for improved foot alignment and pain relief.
  • the insole 100 also introduces an innovative approach to therapeutic regimes through the use of various rotating ingredients. Similar to a "ketchup pack,” multiple packets of ingredients can be applied at various stages of therapy. These packets contain different active ingredients and strengths, which users can apply as required. This system not only enhances the therapeutic effectiveness of the insole but also promotes reusability and customization according to individual therapy needs.
  • various models of the insole 100 are designed to absorb excess sweat and reduce damaging mechanical energy while delivering therapeutic ingredients.
  • the choice of material for these insoles is crucial in providing the necessary support, comfort, and functionality for different foot conditions and user preferences.
  • Each material offers unique properties such as shock absorption, durability, cushioning, and breathability.
  • materials like memory foam provide excellent cushioning and pressure relief, while thermoplastic polymers offer superior durability and support.
  • Memory' foam insoles are crafted from viscoelastic polyurethane foam that molds to the contours of the foot, providing personalized support and cushioning. This material is known for its ability to distribute weight evenly, relieving pressure points effectively. It excels in shock absorption, minimizing the impact on joints and providing a soft, cushioned feel that enhances overall foot comfort. Memory' foam insoles are particularly beneficial for individuals who spend long periods standing or walking, as well as those with conditions like arthritis or sensitive feet. A study published in the Journal of the American Podiatric Medical Association in 2020 highlighted that memory' foam insoles significantly reduced plantar pressure and enhanced comfort for patients experiencing foot pain.
  • Gel insoles typically consist of a silicone or polyurethane gel encased within a fabric or plastic cover, offering a blend of flexibility and cushioning. These insoles provide superior cushioning, adapting to the foot’s movements, and some variants also deliver a cooling sensation, which helps in reducing heat and sweat build-up. Gel insoles are know n for their durability, maintaining their shape and functionality over time. They are particularly suited for athletes and individuals engaged in high-impact activities, and are beneficial for conditions such as plantar fasciitis or heel spurs. Research from the Journal of Orthopaedic & Sports Physical Therapy in 2018 demonstrated that gel insoles significantly improved gait and reduced pain for athletes suffering from plantar fasciitis.
  • EVA is a lightweight, flexible material widely used in athletic shoes and insoles. renowned for its excellent shock absorption properties. It does not significantly add weight to the shoe, making it ideal for athletic pursuits. EVA can be molded to provide tailored support and cushioning, making it popular in sports insoles and orthotic devices. It is particularly suitable for individuals with flat feet or high arches. A 2019 study in Foot & Ankle International found that EVA insoles effectively alleviated pain and enhanced function in patients with flat feet.
  • Cork insoles are crafted from natural cork material, offering firm yet flexible support that gradually molds to the foot’s shape. Cork is a sustainable and biodegradable material, making these insoles an eco-friendly option. It naturally wicks moisture and provides a stable platform, enhancing arch support. Cork insoles are ideal for individuals with plantar fasciitis or heel pain and those seeking environmentally friendly options. A 2017 study in the Journal of Foot and Ankle Research showed that cork insoles improved foot alignment and reduced pain in patients with plantar fasciitis.
  • Poron is a microcellular urethane known for its high energy absorption and impact resistance. It offers a balance of cushioning and support, returning energy with each step, and maintains its cushioning properties over time. Poron insoles are breathable, allowing air circulation which helps in reducing sweat and odor. They are ideal for individuals with high-impact lifestyles or sports activities and provide protective cushioning for people with diabetes or neuropathy. A 2020 study in the Journal of Rehabilitation Research and Development found that Poron insoles effectively reduced plantar pressure and improved gait in patients with diabetic neuropathy.
  • Polyurethane foam is a versatile material used in various insole types, offering a balance of cushioning and support. It absorbs impact effectively, reducing stress on the feet and joints, and retains its shape and functionality 7 over time. Polyurethane foam insoles are suitable for general use, sports, and orthotic applications, and are ideal for individuals w ith plantar fasciitis or heel spurs. Research in Clinical Biomechanics in 2018 show ed that polyurethane foam insoles significantly improved comfort and reduced pain in patients with heel spurs.
  • Neoprene is a synthetic rubber material known for its flexibility and cushioning properties. It is water-resistant, helping to keep feet dry, and provides insulation, keeping feet warm in cold conditions. Neoprene offers a soft, comfortable feel, reducing pressure points. It is ideal for individuals with arthritis or circulation issues and is suitable for use in cold climates or outdoor activities. A 2019 study in the Archives of Physical Medicine and Rehabilitation found that neoprene insoles effectively reduced pain and improved balance in elderly patients with arthritis.
  • leather insoles provide a natural, breathable surface that conforms to the foot’s shape over time. They allow air to circulate, reducing moisture and odor, and are durable, maintaining their shape and support. Leather insoles offer a soft, cushioned feel, enhancing overall foot comfort. They are suitable for individuals with sensitive skin or allergies to synthetic materials and are ideal for those seeking a natural, eco-friendly option. Research in the Journal of the American Podiatric Medical Association in 2018 demonstrated that leather insoles improved comfort and reduced pain in patients with diabetic neuropathy.
  • Carbon fiber insoles are lightweight, strong, and durable, providing excellent support and stability. They offer firm support and stability, reducing foot movement and strain, and do not add significant weight to the shoe, making them ideal for athletic activities. Carbon fiber maintains its shape and support over time, even under high stress. These insoles are ideal for athletes and individuals involved in high-impact activities and are suitable for people with flat feet or high arches. A 2020 study in Sports Medicine found that carbon fiber insoles effectively reduced pain and improved performance in athletes with flat feet.
  • insoles are designed to provide additional padding and absorb shock, reducing pressure on the foot and providing comfort during activities.
  • Common materials used in cushioning insoles include foam, gel, and air-cushioned materials. They are ideal for individuals with general foot fatigue, heel pain, or those seeking additional comfort during prolonged standing or walking.
  • Arch support insoles are designed to support the arch of the foot, helping to distribute pressure more evenly and align the foot in a more natural position. They are typically made from rigid or semi-rigid plastic, foam, or gel. These insoles are beneficial for individuals with flat feet (pes planus), high arches (pes cavus), or conditions like plantar fasciitis.
  • Orthotic inserts are custom or prefabricated devices designed to correct abnormal foot mechanics and provide support where needed. They are made from materials such as hard plastic, graphite, or a combination of materials customized to the individual’s needs. Orthotic inserts are used for a wide range of conditions including plantar fasciitis, heel spurs, Achilles tendonitis, and diabetic foot ulcers.
  • Heel cups and pads are inserts placed under the heel to provide cushioning and support, reducing impact and pressure on the heel area. These are commonly made from gel, foam, or rubber. Heel cups and pads are helpful for conditions like heel spurs, Achilles tendonitis, and general heel pain.
  • Metatarsal pads are small pads placed under the ball of the foot to redistribute pressure away from the metatarsal heads. They are typically made from foam, gel, or rubber. Metatarsal pads are used for conditions like metatarsalgia, Morton’s neuroma, and general forefoot pain.
  • Diabetic insoles are designed to provide extra cushioning and reduce pressure points, helping to protect the sensitive feet of individuals with diabetes. These insoles are made from soft, supportive materials like memory foam or silicone. They are aimed at preventing foot ulcers and other complications in diabetic patients.
  • Embarrassment and shame are not uncommon, particularly when the foot pain leads to visible symptoms such as swelling, redness, or changes in gait. These physical manifestations can make individuals self-conscious, leading to a sense of shame associated with their perceived weakness or inability to keep up with peers.
  • the fear of becoming dependent on others can be a significant source of anxiety for those with chronic foot pain.
  • the potential need for assistance or adaptive devices may lead to concerns about losing independence and being perceived as weak or vulnerable.
  • Chronic foot pain can also take a toll on an individual's self-esteem. Changes in physical ability and appearance, such as limping or using mobility aids, can negatively impact body image. The inability' to engage in previously enjoyed activities may lead to a diminished sense of self-worth.
  • Pain-free feet can lead to increased confidence and empow erment, as individuals find themselves able to take on new challenges and activities. This physical capability often translates to improved body image and self-esteem, contributing to a more positive self-perception.
  • Mechanism of Action Acts as a counter-irritant, causing mild inflammation and providing a sensation of warmth which distracts from deeper pain.
  • Effectiveness Commonly used in topical pain relief creams and ointments. Effective for temporary relief of minor aches and pains of muscles and joints associated with arthritis, backache, strains, and sprains.
  • VAS visual analog scale
  • Methyl salicylate was effective for short-term relief of both acute and chronic musculoskeletal pain, with a moderate effect size (standardized mean difference of 0.6).
  • Mechanism of Action Depletes substance P. a neurotransmitter involved in sending pain messages to the brain.
  • Effectiveness Effective for conditions such as arthritis, muscle pain, and neuropathic pain. Provides long-term pain relief with regular use.
  • Mechanism of Action Acts as a counter-irritant, producing a cooling sensation followed by warmth.
  • Effectiveness Used for temporary' relief of pain and inflammation in muscles and joints. Also used to relieve itching and irritation.
  • Effectiveness Widely used in topical analgesics for temporary relief of minor aches and pains. Also used to soothe itching.
  • Mechanism of Action Contains anti-inflammatory compounds and provides a cooling sensation.
  • Effectiveness Used for pain relief in conditions such as arthritis, muscle pain, and sinus congestion.
  • Mechanism of Action Acts as a keratolytic agent, softening and moisturizing the skin.
  • Effectiveness Primarily used to treat dry, rough skin conditions. Can enhance the penetration of other topical medications.
  • Vitamin A (Retinol)
  • Effectiveness Used in skin care for its anti-aging and skin renewal properties. May help in healing minor wounds.
  • Mechanism of Action Acts as an antioxidant, protecting cells from damage.
  • Effectiveness Used to moisturize and heal the skin. May help in reducing inflammation and promoting wound healing.
  • Vitamin E significantly improved scar texture and appearance (mean improvement of 20%) compared to the placebo group.
  • Vitamin E was effective in protecting the skin from oxidative stress and enhancing overall skin health, with consistent positive outcomes across studies.

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Rheumatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Wood Science & Technology (AREA)
  • Footwear And Its Accessory, Manufacturing Method And Apparatuses (AREA)

Abstract

La présente divulgation concerne une semelle intérieure de chaussure thérapeutique comprenant une section de corps comportant une section à mi-pied présentant un sommet formant une hauteur de voûte et une section de talon. La semelle intérieure comporte un matériau polymère formant au moins une partie de la section de corps, le matériau polymère comprenant des pores contenant au moins un principe actif à libération contrôlée. Le principe actif peut être un composé analgésique, anti-inflammatoire ou antimicrobien. La semelle intérieure peut en outre comprendre un trou au niveau du talon dans la section de talon, éventuellement rempli d'un matériau d'amortissement, et un coussinet de rembourrage métatarsien à proximité d'une extrémité avant de la semelle intérieure. L'invention concerne également un procédé de fabrication de la semelle intérieure et un système de personnalisation de la semelle intérieure sur la base de critères spécifiques à l'utilisateur.
PCT/US2024/046265 2023-09-11 2024-09-11 Semelle intérieure de chaussure thérapeutique auto-assemblée avec distribution de principe actif Pending WO2025059223A1 (fr)

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Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030009138A1 (en) * 2001-06-04 2003-01-09 Freeman Cindy N. Aromatherapy footwear
US20080220065A1 (en) * 2007-03-07 2008-09-11 David Robert Gelvin Compositions for treating foot odor and methods of use thereof
US20100226947A1 (en) * 2008-07-18 2010-09-09 Biomod Inc. Articles of manufacture releasing an active ingredient
US20110078920A1 (en) * 2008-07-09 2011-04-07 Evonik Degussa Gmbh Sweat-absorbing shoe sole inserts having improved sweat absorption
US20150335742A1 (en) * 2014-05-05 2015-11-26 Shannon Vissman Bioceramic compositions and biomodulatory uses thereof
WO2016012039A1 (fr) * 2014-07-22 2016-01-28 Versailles B.V. Enveloppe de pied pour appliquer une formulation à un pied
US20200329815A1 (en) * 2019-04-19 2020-10-22 Michael John Schmid Footwear and apparatus and method for making same
WO2021173898A1 (fr) * 2020-02-26 2021-09-02 Kiki Price Llc Semelle intérieure de chaussure pour fournir un confort et réduire la douleur dans des chaussures à talon haut et des chaussures, construites à partir d'une forme de forme anatomique
US20220047037A1 (en) * 2020-08-14 2022-02-17 Charlene Kelley Andrew Odor-Eliminating Insole
US20220071353A1 (en) * 2018-06-14 2022-03-10 Scholl's Wellness Company Llc Insole

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030009138A1 (en) * 2001-06-04 2003-01-09 Freeman Cindy N. Aromatherapy footwear
US20080220065A1 (en) * 2007-03-07 2008-09-11 David Robert Gelvin Compositions for treating foot odor and methods of use thereof
US20110078920A1 (en) * 2008-07-09 2011-04-07 Evonik Degussa Gmbh Sweat-absorbing shoe sole inserts having improved sweat absorption
US20100226947A1 (en) * 2008-07-18 2010-09-09 Biomod Inc. Articles of manufacture releasing an active ingredient
US20150335742A1 (en) * 2014-05-05 2015-11-26 Shannon Vissman Bioceramic compositions and biomodulatory uses thereof
WO2016012039A1 (fr) * 2014-07-22 2016-01-28 Versailles B.V. Enveloppe de pied pour appliquer une formulation à un pied
US20220071353A1 (en) * 2018-06-14 2022-03-10 Scholl's Wellness Company Llc Insole
US20200329815A1 (en) * 2019-04-19 2020-10-22 Michael John Schmid Footwear and apparatus and method for making same
WO2021173898A1 (fr) * 2020-02-26 2021-09-02 Kiki Price Llc Semelle intérieure de chaussure pour fournir un confort et réduire la douleur dans des chaussures à talon haut et des chaussures, construites à partir d'une forme de forme anatomique
US20220047037A1 (en) * 2020-08-14 2022-02-17 Charlene Kelley Andrew Odor-Eliminating Insole

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