WO2025053492A1 - Wearable device for monitoring glaucoma suspect and glaucoma suspect monitoring method - Google Patents
Wearable device for monitoring glaucoma suspect and glaucoma suspect monitoring method Download PDFInfo
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- WO2025053492A1 WO2025053492A1 PCT/KR2024/012365 KR2024012365W WO2025053492A1 WO 2025053492 A1 WO2025053492 A1 WO 2025053492A1 KR 2024012365 W KR2024012365 W KR 2024012365W WO 2025053492 A1 WO2025053492 A1 WO 2025053492A1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
- A61B5/7271—Specific aspects of physiological measurement analysis
- A61B5/7275—Determining trends in physiological measurement data; Predicting development of a medical condition based on physiological measurements, e.g. determining a risk factor
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/02007—Evaluating blood vessel condition, e.g. elasticity, compliance
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/021—Measuring pressure in heart or blood vessels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/021—Measuring pressure in heart or blood vessels
- A61B5/02108—Measuring pressure in heart or blood vessels from analysis of pulse wave characteristics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/024—Measuring pulse rate or heart rate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
- A61B5/024—Measuring pulse rate or heart rate
- A61B5/02416—Measuring pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6813—Specially adapted to be attached to a specific body part
- A61B5/6825—Hand
- A61B5/6826—Finger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
- A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
- A61B5/6843—Monitoring or controlling sensor contact pressure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient; User input means
- A61B5/7455—Details of notification to user or communication with user or patient; User input means characterised by tactile indication, e.g. vibration or electrical stimulation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/74—Details of notification to user or communication with user or patient; User input means
- A61B5/746—Alarms related to a physiological condition, e.g. details of setting alarm thresholds or avoiding false alarms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2560/00—Constructional details of operational features of apparatus; Accessories for medical measuring apparatus
- A61B2560/02—Operational features
- A61B2560/0204—Operational features of power management
- A61B2560/0214—Operational features of power management of power generation or supply
Definitions
- the present invention relates to a wearable device for monitoring glaucoma symptoms and a method for monitoring glaucoma symptoms, and more specifically, to a technology for measuring a user's blood pressure using a wearable device worn on the user's finger and using the blood pressure to determine whether the user has glaucoma symptoms.
- wearable devices are devices that can be worn freely on the body, such as clothes, watches, or glasses. These wearable devices include smart glasses, smart watches, and ring-type wearable devices.
- ring-type wearable devices have the advantage of being convenient to wear due to their small size and light weight, and when a user wears a ring-type wearable device, the inner side of the device and the user's skin come into close contact, making it easy to obtain information about the user's pulse, etc.
- Korean Patent No. 10-2392038 (ring-shaped bio-signal detection device) comprises: a first electrode (10) provided in a ring shape and made of a conductor, which is fitted onto a user's finger and makes contact with the finger; a second electrode (20) assembled on the outside of the first electrode (10), which is made of a conductor, and makes contact with the user's body; an insulating unit (30) which maintains insulation between the first electrode (10) and the second electrode (20); a top cover (50) arranged on one side of the second electrode (20); a printed circuit board (60) arranged inside the second electrode (20); a bio-sensor arranged on the insulating unit (30) and on one side of the insulating unit (30), and which collects a bio-signal of the user when the second electrode (20) makes contact and releases contact twice consecutively with the user's body excluding the user's finger; And a ring-shaped bio-signal detection device is disclosed, which includes a battery (70) disposed inside the second electrode (20) and providing power
- the purpose of the present invention to solve the above problems is to measure a user's blood pressure using a wearable device worn on the user's finger and to use the blood pressure to determine whether the user has glaucoma.
- the present invention comprises: a housing having a ring shape and an internal space; a sensor unit coupled to the housing and in contact with the user's skin to measure the user's pulse wave; a communication unit receiving a signal from the sensor unit, processing it, and generating a transmission signal which is a transmitted signal; and an analysis unit receiving and analyzing the transmission signal; wherein the analysis unit analyzes the user's pulse wave information to determine whether the user has glaucoma.
- the analysis unit can derive blood vessel stiffness (Stiffness Index, SI) using the pulse information.
- SI Blood vessel stiffness Index
- the analysis unit can derive the user's blood pressure value by using the user's vascular stiffness value using a predetermined formula.
- the analysis unit can determine that the user has glaucoma if the average mean arterial pressure (MAP) fluctuation value of the user during the measurement period is greater than a predetermined value.
- MAP mean arterial pressure
- the sensor unit may include a photoplethysmography (PPG) sensor.
- PPG photoplethysmography
- a vibration unit may be further included to transmit an abnormal health signal to the user by receiving an operation signal from the analysis unit and transmitting vibration to the user's skin.
- the housing may further include an elastic member formed in an internal space to allow the sensor unit and the user's skin to come into close contact with each other, and the vibration unit and the user's skin to come into close contact with each other.
- a battery formed in an internal space of the housing and supplying electricity to the sensor unit, the communication unit, and the analysis unit may be further included.
- the analysis unit may be formed in the internal space of the housing or the exterior of the housing.
- the present invention comprises a first step in which the sensor unit detects the user's pulse wave; a second step in which the pulse wave information is transmitted from the sensor unit to the analysis unit, and the analysis unit derives a vascular stiffness index (SI) using the pulse wave information; a third step in which, in the analysis unit, the user's blood pressure value is derived using the user's vascular stiffness value, and the user's average mean arterial pressure (MAP) value is derived hourly within a measurement period; and a fourth step in which, in the analysis unit, if the user's average arterial pressure fluctuation value is greater than a predetermined value, the user is determined to have glaucoma.
- SI vascular stiffness index
- the effect of the present invention according to the above configuration is that when the wearable device of the present invention is used, the wearable device of the present invention is always worn on the user's finger, and pulse measurement, etc. is performed in real time, and continuous analysis of disease occurrence is performed, so that the accuracy and speed of disease diagnosis are improved.
- FIG. 1 is a schematic diagram of a wearable device and a charger according to one embodiment of the present invention.
- Figure 2 is a schematic diagram of the configuration of a wearable device according to one embodiment of the present invention.
- Figure 3 is a flowchart of a blood pressure measurement process of an analysis unit according to one embodiment of the present invention.
- Figure 4 is a measurement graph using a photoplethysmography sensor according to one embodiment of the present invention.
- Figures 5 to 7 are graphs for mean intraocular pressure, mean arterial pressure, and mean ocular perfusion pressure, respectively.
- the most preferred embodiment according to the present invention comprises: a housing having a ring shape and an internal space; a sensor unit coupled to the housing and in contact with the user's skin to measure the user's pulse wave; a communication unit receiving a signal from the sensor unit, processing it, and generating a transmission signal which is a transmitted signal; and an analysis unit receiving and analyzing the transmission signal; wherein the analysis unit analyzes the user's pulse wave information to determine whether the user has glaucoma.
- FIG. 1 is a schematic diagram of a wearable device and a charger according to an embodiment of the present invention
- FIG. 2 is a schematic diagram of the configuration of a wearable device according to an embodiment of the present invention.
- (a) of FIG. 1 is a schematic diagram of a wearable device of the present invention
- (b) of FIG. 1 is a schematic diagram of a charger of the present invention.
- the wearable device of the present invention includes a housing (160) having a ring shape and an internal space; a sensor unit (110) coupled to the housing (160) and in contact with the user's skin to measure the user's pulse wave; a communication unit (130) that receives and processes a signal from the sensor unit (110) to generate a transmission signal, which is a transmitted signal; and an analysis unit (120) that receives and analyzes the transmission signal.
- the analysis unit (120) can analyze the user's pulse wave information to determine the user's glaucoma symptoms.
- the housing (160) has a ring shape and can be worn on the user's finger, and accordingly, the inner surface of the housing (160) can be in contact with the user's finger skin.
- the outer surface of the housing (160) exposed to the outside can be formed of a metal material such as titanium or stainless steel (SUS), and the inner surface of the housing (160) can be formed of a non-metal such as plastic.
- the material forming each part of the housing (160) is not limited thereto, and it goes without saying that various materials can be used.
- the wearable device of the present invention may further include a vibration unit (140) that receives an operating signal from an analysis unit (120) and transmits vibration to the user's skin to transmit a health abnormality signal to the user.
- a vibration unit 140
- the analysis unit (120) determines that the user has glaucoma through the following process
- the analysis unit (120) transmits an operating signal to the vibration unit (140), and the vibration unit (140) generates vibration in response to the operating signal, so that the vibration is transmitted from the vibration unit (140) to the user's skin, and thereby the user can recognize that he or she has glaucoma.
- the elastic member may include a first elastic body (151) that has elasticity and is formed in the internal space of the housing (160) and is combined with the sensor member (110) to press the sensor member (110) toward the center of the housing (160), and a second elastic body (152) that has elasticity and is formed in the internal space of the housing (160) and is combined with the vibrating member (140) to press the vibrating member (140) toward the center of the housing (160).
- the skin of the user's finger presses the protruding portion of the sensor portion (110) and the protruding portion of the vibrating portion (140), respectively, and at the same time, the pressing force of the first elastic body (151) and the pressing force of the second elastic body (152), which correspond to the pressing force of the finger, are transmitted to the sensor portion (110) and the vibrating portion (140), respectively, so that the sensor portion (110) and the vibrating portion (140) can be in close contact with the skin of the user's finger.
- the wearable device of the present invention may further include a battery (170) formed in the internal space of the housing (160) and supplying electricity to the sensor unit (110), the communication unit (130), and the analysis unit (120). In addition, electricity may be supplied from the battery (170) to the vibrating unit (140).
- a battery (170) may be formed as a rechargeable type and may operate by supplying electricity to each of the above-described components.
- the analysis unit (120) may be formed in the internal space of the housing (160) or on the outside of the housing (160). In FIG. 2, the analysis unit (120) is shown to be formed in the internal space of the housing (160), but the analysis unit (120) may also be formed on the outside of the housing (160). Specifically, the analysis unit (120) may be installed in an external electronic device such as a computer, a smartphone, a tablet PC, or a smartwatch to perform the same function.
- an external electronic device such as a computer, a smartphone, a tablet PC, or a smartwatch to perform the same function.
- Fig. 3 is a flow chart of a blood pressure measurement process of an analysis unit (120) according to an embodiment of the present invention
- Fig. 4 is a measurement graph by a photoplethysmography sensor according to an embodiment of the present invention.
- the horizontal axis is the number of detections and the vertical axis is a detection intensity value (dimensionless number compared to the maximum detection intensity value) by a photoplethysmography (PPG) sensor.
- PPG photoplethysmography
- the analysis unit (120) may perform a peak measurement step (S111) of measuring the time difference between the primary peak and the secondary peak that appear when measuring the pulse; a height selection step (S112) of selecting the user's height; an SI calculation step (S120) of calculating an SI value; and a blood pressure measurement step (S130) of deriving the user's blood pressure value using the SI value.
- the analysis unit (120) can derive the vascular stiffness (Stiffness Index, SI) using the pulse wave information.
- SI vascular stiffness Index
- the vascular stiffness (SI) can be calculated by the following [Mathematical Formula 1].
- SI is the vascular stiffness index (SI) value
- h is the user's height
- ⁇ T is the time difference between the primary peak and the secondary peak that appear when measuring the user's pulse wave.
- Information about the height of a user wearing the wearable device of the present invention may be stored in advance in the analysis unit (120), and the sensor unit (110) is equipped with a photoplethysmography (PPG: Photo-PlethysmoGraphy) sensor, so that, as shown in FIG. 4, the sensor unit (110) can continuously detect each of the primary peak and secondary peak of the pulse wave over time.
- PPG Photo-PlethysmoGraphy
- the pulse graph is a graph of a wave formed by multiple unit waves as one-cycle waves having one-cycle wavelength ( ⁇ ), and each unit wave may have a first peak (a in Fig. 4) and a second peak (b in Fig. 4).
- the analysis unit (120) can derive the user's blood pressure value by using the user's blood vessel stiffness value by [Mathematical Formula 2] below.
- BP blood pressure
- SI vascular stiffness
- a and b are each constants predetermined for each user.
- the SI value can be measured in advance using the wearable device of the present invention and the user's blood pressure can be measured using an external device, and the data on this can be input into the analysis unit (120).
- the analysis unit (120) can use this data to derive the a and b values of [Mathematical Formula 2], and store them as constants of [Mathematical Formula 2].
- blood pressure can be measured in the analysis unit (120), and such blood pressure is derived by the SI value, and thus, the user's blood pressure fluctuations over time can also be derived according to the fluctuations in the SI value over time.
- Such blood pressure fluctuations can be measured as the mean arterial pressure (MAP) fluctuations below.
- Figures 5 to 7 are graphs for mean intraocular pressure, mean arterial pressure, and mean ocular perfusion pressure, respectively.
- FIG. 5 is a graph of the hourly mean intraocular pressure (IOP) measured during a given measurement time during a day for two patients (Patient 1, Patient 2)
- FIG. 6 is a graph of the hourly mean arterial pressure (MAP) measured during a given measurement time during a day for the two patients (Patient 1, Patient 2)
- FIG. 7 is a graph of the hourly mean ocular perfusion pressure (MOPP) measured during a given measurement time during a day for the two patients (Patient 1, Patient 2).
- IOP hourly mean intraocular pressure
- MAP hourly mean arterial pressure
- MOPP hourly mean ocular perfusion pressure
- the horizontal axis represents time
- the vertical axis represents mean intraocular pressure (IOP), mean arterial pressure (MAP), and mean ocular perfusion pressure (MOPP), respectively.
- the trend of the average intraocular pressure fluctuation (IOP fluctuation) value per patient is related to the trend of the average arterial pressure fluctuation (MAP fluctuation) value and the trend of the average ocular perfusion pressure fluctuation (MOPP fluctuation) value per patient.
- the user's blood pressure fluctuation affects the average intraocular pressure fluctuation (IOP fluctuation), and patients with severe average intraocular pressure fluctuation (IOP fluctuation) have a high incidence of glaucoma, i.e., can be diagnosed as having symptoms of glaucoma.
- IOP fluctuation average intraocular pressure fluctuation
- IOP fluctuation patients with severe average intraocular pressure fluctuation
- the analysis unit (120) can determine that the user has glaucoma if the average mean arterial pressure (MAP) fluctuation value of the user during the measurement period is greater than a predetermined value.
- MAP mean arterial pressure
- the analysis unit (120) stores a reference fluctuation value, which is a fluctuation value of the mean arterial pressure that serves as a reference for a user wearing the wearable device of the present invention, and the analysis unit (120), which receives a signal from the sensor unit (110) as described above and derives the user's blood pressure fluctuation, can continuously measure the fluctuation value of the mean arterial pressure by hour, and if the analysis unit (120) analyzes that the user's fluctuation value of the mean arterial pressure exceeds the reference fluctuation value during the measurement of the fluctuation value of the mean arterial pressure by hour within a preset measurement period, the analysis unit (120) can determine that the user has glaucoma.
- a reference fluctuation value which is a fluctuation value of the mean arterial pressure that serves as a reference for a user wearing the wearable device of the present invention
- an operating signal is transmitted from the analysis unit (120) to the vibration unit (140), the vibration unit (140) operates, and the vibration of the vibration unit (140) is transmitted to the user's finger, so that the user can confirm that he or she has glaucoma.
- a glaucoma monitoring system can be formed, including a wearable device of the present invention as described above, and a charger that is selectively combined with the wearable device of the present invention to perform charging.
- the charger may include a body (210) that wirelessly charges a battery (170) when adjacent to the wearable device of the present invention; and a holder (220) that is formed by protruding from the upper surface of the body (210) and into which the wearable device of the present invention is fitted.
- a terminal (211) connected to a power cable and receiving electricity from a power source may be formed on the body (210), and an indicator (221) may be formed on the upper surface of the holder (220) to indicate with light whether the battery (170) is being charged, whether the battery (170) is fully charged, etc. (each distinguished by color).
- the glaucoma monitoring system may further include a central processing unit formed outside the wearable device of the present invention to receive information from a plurality of wearable devices and perform collection and analysis of the information.
- the central processing unit can use information from multiple wearable devices to classify users into each patient group, and perform analysis on trends in mean arterial pressure fluctuation (MAP fluctuation), mean intraocular pressure fluctuation (IOP fluctuation), and mean ocular perfusion pressure fluctuation in each patient group, and use patient diagnosis data according to IOP input into the central processing unit to derive the above-mentioned reference fluctuation value that serves as a diagnostic criterion in each patient group.
- MAP fluctuation mean arterial pressure fluctuation
- IOP fluctuation mean intraocular pressure fluctuation
- mean ocular perfusion pressure fluctuation mean ocular perfusion pressure fluctuation
- patient information such as male and female gender, patient age, patient height and weight, etc.
- the central processing unit can also receive information on the wearing user from the analysis unit (120), and if the user belongs to a certain patient group, selects a standard change value suitable for the patient group and transmits it to the analysis unit (120), and the analysis unit (120) can perform the above analysis judgment using the standard change value.
- the mean arterial pressure fluctuation (MAP fluctuation) is derived by measuring the user's pulse, and whether the user has glaucoma is determined based on this MAP fluctuation information, so that the measurement is quick and at the same time, the onset of glaucoma can be easily determined and analyzed.
- the wearable device of the present invention when using the wearable device of the present invention, the wearable device of the present invention is always worn on the user's finger, and pulse measurement, etc. is performed in real time, and continuous analysis of disease occurrence is performed, so that the accuracy and speed of disease diagnosis, etc. can be improved.
- the sensor unit (110) can detect the user's pulse wave.
- the pulse wave information is transmitted from the sensor unit (110) to the analysis unit (120), and the analysis unit (120) can derive the blood vessel stiffness (Stiffness Index, SI) using the pulse wave information.
- the analysis unit (120) can derive the user's blood pressure value using the user's vascular stiffness value, and derive the user's average mean arterial pressure (MAP) value by hour within the measurement period. Then, in the fourth step, the analysis unit (120) can determine that the user has glaucoma if the user's average arterial pressure fluctuation value is greater than a predetermined value.
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Abstract
Description
본 발명은 녹내장의증 모니터링을 위한 웨어러블 장치 및 녹내장의증 모니터링 방법에 관한 것으로, 더욱 상세하게는, 사용자의 손가락에 착용하는 웨어러블 장치를 이용하여 사용자의 혈압을 측정하고 이를 이용하여 사용자의 녹내장의증 발생 여부를 판단하도록 하는 기술에 관한 것이다.The present invention relates to a wearable device for monitoring glaucoma symptoms and a method for monitoring glaucoma symptoms, and more specifically, to a technology for measuring a user's blood pressure using a wearable device worn on the user's finger and using the blood pressure to determine whether the user has glaucoma symptoms.
일반적으로 웨어러블 기기(wearable device)는 옷, 시계 또는 안경처럼 자유롭게 몸에 착용하고 다닐 수 있는 장치로서, 이러한 웨어러블 기기에는 스마트 글래스, 스마트 워치, 및 반지형 웨어러블 기기 등이 있다.In general, wearable devices are devices that can be worn freely on the body, such as clothes, watches, or glasses. These wearable devices include smart glasses, smart watches, and ring-type wearable devices.
이 중에서 반지형 웨어러블 기기는 소형의 크기와 가벼운 중량으로 착용의 편리함이 있으며, 사용자가 반지형 웨어러블 기기를 착용하는 경우, 해당 기기의 내측면과 사용자의 피부가 밀착되게 되어 사용자의 맥박 등에 대한 정보를 획득하기에 용이하다는 장점이 있다.Among these, ring-type wearable devices have the advantage of being convenient to wear due to their small size and light weight, and when a user wears a ring-type wearable device, the inner side of the device and the user's skin come into close contact, making it easy to obtain information about the user's pulse, etc.
최근에는 생세신호를 측정하는 생체인식센서(Biometric Sensor) 등의 소형화로 이와 같은 반지형 웨이러블 기기의 구현이 용이하게 되었으며, 동시에, 사용자의 생체 신호를 인식하여 사용자의 건강 상태를 진단하는 기술에 대한 수요 증가로 해당 기술에 대한 연구 개발이 증가하고 있다.Recently, the miniaturization of biometric sensors that measure vital signs has made it easier to implement ring-type wearable devices like this one. At the same time, demand for technologies that recognize users' vital signs and diagnose their health conditions has increased, leading to an increase in research and development on such technologies.
대한민국 등록특허 제10-2392038호(반지 형태의 생체신호 감지 장치)에서는, 링(ring) 형상으로 제공되고 도체로 구성되며 사용자 손가락에 끼워져 손가락과 접촉되는 제1 전극(10); 상기 제1 전극(10)의 바깥쪽에 조립되고 도체로 구성되며 사용자의 신체에 접촉되는 제2 전극(20); 상기 제1 전극(10)과 상기 제2 전극(20) 간에 절연을 유지하는 절연 유닛(30); 상기 제2 전극(20)의 한쪽에 배치된 탑 커버(50); 상기 제2 전극(20)의 내부에 배치되는 인쇄회로기판(60); 상기 절연 유닛(30)에 배치되고, 상기 절연 유닛(30)의 한쪽에 배치되는 생체 센서가 포함되며, 상기 제2 전극(20)이 상기 사용자 손가락을 제외한 사용자의 신체에 2회 연속으로 접촉과 접촉 해제하면 상기 사용자의 생체신호를 수집하는 제어부(40); 및 상기 제2 전극(20)의 내부에 배치되고 상기 제1 전극(10), 상기 제2전극(20), 상기 인쇄회로기판(60) 및 상기 제어부(40)에 전원을 제공하는 배터리(70)를 포함하는 반지 형태의 생체신호 감지 장치가 개시되어 있다.Korean Patent No. 10-2392038 (ring-shaped bio-signal detection device) comprises: a first electrode (10) provided in a ring shape and made of a conductor, which is fitted onto a user's finger and makes contact with the finger; a second electrode (20) assembled on the outside of the first electrode (10), which is made of a conductor, and makes contact with the user's body; an insulating unit (30) which maintains insulation between the first electrode (10) and the second electrode (20); a top cover (50) arranged on one side of the second electrode (20); a printed circuit board (60) arranged inside the second electrode (20); a bio-sensor arranged on the insulating unit (30) and on one side of the insulating unit (30), and which collects a bio-signal of the user when the second electrode (20) makes contact and releases contact twice consecutively with the user's body excluding the user's finger; And a ring-shaped bio-signal detection device is disclosed, which includes a battery (70) disposed inside the second electrode (20) and providing power to the first electrode (10), the second electrode (20), the printed circuit board (60), and the control unit (40).
<선행기술문헌><Prior art literature>
대한민국 등록특허 제10-2392038호Republic of Korea Patent No. 10-2392038
상기와 같은 문제점을 해결하기 위한 본 발명의 목적은, 사용자의 손가락에 착용하는 웨어러블 장치를 이용하여 사용자의 혈압을 측정하고 이를 이용하여 사용자의 녹내장의증 발생 여부를 판단하도록 하는 것이다.The purpose of the present invention to solve the above problems is to measure a user's blood pressure using a wearable device worn on the user's finger and to use the blood pressure to determine whether the user has glaucoma.
본 발명이 이루고자 하는 기술적 과제는 이상에서 언급한 기술적 과제로 제한되지 않으며, 언급되지 않은 또 다른 기술적 과제들은 아래의 기재로부터 본 발명이 속하는 기술 분야에서 통상의 지식을 가진 자에게 명확하게 이해될 수 있을 것이다.The technical problems to be achieved by the present invention are not limited to the technical problems mentioned above, and other technical problems not mentioned can be clearly understood by a person having ordinary skill in the technical field to which the present invention belongs from the description below.
상기와 같은 목적을 달성하기 위한 본 발명의 구성은, 링 형상을 구비하고 내부 공간을 구비하는 하우징; 상기 하우징에 결합되고, 사용자의 피부와 접촉하여 상기 사용자의 맥파를 측정하는 센서부; 상기 센서부의 신호를 전달받아 처리하여 송신되는 신호인 송신신호를 생성하는 통신부; 및 상기 송신신호를 전달받아 분석하는 분석부;를 포함하고, 상기 분석부에서는, 상기 사용자의 맥파 정보를 분석하여 상기 사용자의 녹내장의증을 판단하는 것을 특징으로 한다.In order to achieve the above-described purpose, the present invention comprises: a housing having a ring shape and an internal space; a sensor unit coupled to the housing and in contact with the user's skin to measure the user's pulse wave; a communication unit receiving a signal from the sensor unit, processing it, and generating a transmission signal which is a transmitted signal; and an analysis unit receiving and analyzing the transmission signal; wherein the analysis unit analyzes the user's pulse wave information to determine whether the user has glaucoma.
본 발명의 실시 예에 있어서, 상기 분석부는, 상기 맥파 정보를 이용하여 혈관강성도((Stiffness Index, SI)를 도출할 수 있다.In an embodiment of the present invention, the analysis unit can derive blood vessel stiffness (Stiffness Index, SI) using the pulse information.
본 발명의 실시 예에 있어서, 상기 분석부는, 소정의 식에 의해 상기 사용자의 혈관강성도 값을 이용하여 상기 사용자의 혈압 값을 도출할 수 있다.In an embodiment of the present invention, the analysis unit can derive the user's blood pressure value by using the user's vascular stiffness value using a predetermined formula.
본 발명의 실시 예에 있어서, 상기 분석부에서는, 측정 기간 내 상기 사용자의 평균동맥압(Average mean arterial pressure, MAP) 변동 값이 소정의 값 이상인 경우 상기 사용자가 녹내장의증이라고 판단할 수 있다.In an embodiment of the present invention, the analysis unit can determine that the user has glaucoma if the average mean arterial pressure (MAP) fluctuation value of the user during the measurement period is greater than a predetermined value.
본 발명의 실시 예에 있어서, 상기 센서부는, 광혈류측정(PPG: Photo-PlethysmoGraphy) 센서를 구비할 수 있다.In an embodiment of the present invention, the sensor unit may include a photoplethysmography (PPG) sensor.
본 발명의 실시 예에 있어서, 상기 분석부로부터 작동신호를 전달받아 상기 사용자의 피부에 진동을 전달함으로써 상기 사용자에게 건강 이상 신호를 전달하는 진동부를 더 포함할 수 있다.In an embodiment of the present invention, a vibration unit may be further included to transmit an abnormal health signal to the user by receiving an operation signal from the analysis unit and transmitting vibration to the user's skin.
본 발명의 실시 예에 있어서, 상기 하우징의 내부 공간에 형성되고, 상기 센서부와 상기 사용자의 피부가 밀착되도록 하며 상기 진동부와 상기 사용자의 피부가 밀착되도록 하는 탄성부를 더 포함할 수 있다.In an embodiment of the present invention, the housing may further include an elastic member formed in an internal space to allow the sensor unit and the user's skin to come into close contact with each other, and the vibration unit and the user's skin to come into close contact with each other.
본 발명의 실시 예에 있어서, 상기 하우징의 내부 공간에 형성되고, 상기 센서부와 상기 통신부 및 상기 분석부로 전기를 공급하는 배터리를 더 포함할 수 있다.In an embodiment of the present invention, a battery formed in an internal space of the housing and supplying electricity to the sensor unit, the communication unit, and the analysis unit may be further included.
본 발명의 실시 예에 있어서, 상기 분석부는, 상기 하우징의 내부 공간 또는 상기 하우징의 외부에 형성될 수 있다.In an embodiment of the present invention, the analysis unit may be formed in the internal space of the housing or the exterior of the housing.
상기와 같은 목적을 달성하기 위한 본 발명의 구성은, 상기 센서부에서 상기 사용자의 맥파를 감지하는 제1단계; 상기 센서부로부터 상기 분석부로 상기 맥파 정보가 전달되고, 상기 분석부에서 상기 맥파 정보를 이용하여 혈관강성도((Stiffness Index, SI)를 도출하는 제2단계; 상기 분석부에서, 상기 사용자의 혈관강성도 값을 이용하여 상기 사용자의 혈압 값을 도출하고, 측정 기간 내 시간별 상기 사용자의 평균동맥압(Average mean arterial pressure, MAP) 값을 도출하는 제3단계; 및 상기 분석부에서, 상기 사용자의 평균동맥압 변동 값이 소정의 값 이상인 경우 상기 사용자가 녹내장의증이라고 판단하는 제4단계;를 포함한다.In order to achieve the above purpose, the present invention comprises a first step in which the sensor unit detects the user's pulse wave; a second step in which the pulse wave information is transmitted from the sensor unit to the analysis unit, and the analysis unit derives a vascular stiffness index (SI) using the pulse wave information; a third step in which, in the analysis unit, the user's blood pressure value is derived using the user's vascular stiffness value, and the user's average mean arterial pressure (MAP) value is derived hourly within a measurement period; and a fourth step in which, in the analysis unit, if the user's average arterial pressure fluctuation value is greater than a predetermined value, the user is determined to have glaucoma.
상기와 같은 구성에 따른 본 발명의 효과는, 본 발명의 웨어러블 장치를 이용하는 경우, 항상 사용자의 손가락에 본 발명의 웨어러블 장치를 착용하여 실시간으로 맥파 측정 등이 수행되며, 질병 발생에 대한 지속적인 분석이 수행되므로, 질병 진단의 정확도와 진단 속도 등이 향상된다는 것이다.The effect of the present invention according to the above configuration is that when the wearable device of the present invention is used, the wearable device of the present invention is always worn on the user's finger, and pulse measurement, etc. is performed in real time, and continuous analysis of disease occurrence is performed, so that the accuracy and speed of disease diagnosis are improved.
본 발명의 효과는 상기한 효과로 한정되는 것은 아니며, 본 발명의 상세한 설명 또는 특허청구범위에 기재된 발명의 구성으로부터 추론 가능한 모든 효과를 포함하는 것으로 이해되어야 한다.The effects of the present invention are not limited to the effects described above, and should be understood to include all effects that can be inferred from the detailed description of the present invention or the composition of the invention described in the claims.
도 1은 본 발명의 일 실시 예에 따른 웨어러블 장치와 충전기에 대한 모식도이다.FIG. 1 is a schematic diagram of a wearable device and a charger according to one embodiment of the present invention.
도 2는 본 발명의 일 실시 예에 따른 웨어러블 장치의 구성에 대한 모식도이다.Figure 2 is a schematic diagram of the configuration of a wearable device according to one embodiment of the present invention.
도 3은 본 발명의 일 실시 예에 따른 분석부의 혈압 측정 과정에 대한 순서도이다.Figure 3 is a flowchart of a blood pressure measurement process of an analysis unit according to one embodiment of the present invention.
도 4는 본 발명의 일 실시 예에 따른 광혈류측정 센서에 의한 측정 그래프이다.Figure 4 is a measurement graph using a photoplethysmography sensor according to one embodiment of the present invention.
도 5 내지 도 7은 평균 안압과 평균동맥압 및 평균 안구관류압 각각에 대한 그래프이다.Figures 5 to 7 are graphs for mean intraocular pressure, mean arterial pressure, and mean ocular perfusion pressure, respectively.
본 발명에 따른 가장 바람직한 일 실시예는, 링 형상을 구비하고 내부 공간을 구비하는 하우징; 상기 하우징에 결합되고, 사용자의 피부와 접촉하여 상기 사용자의 맥파를 측정하는 센서부; 상기 센서부의 신호를 전달받아 처리하여 송신되는 신호인 송신신호를 생성하는 통신부; 및 상기 송신신호를 전달받아 분석하는 분석부;를 포함하고, 상기 분석부에서는, 상기 사용자의 맥파 정보를 분석하여 상기 사용자의 녹내장의증을 판단하는 것을 특징으로 한다.The most preferred embodiment according to the present invention comprises: a housing having a ring shape and an internal space; a sensor unit coupled to the housing and in contact with the user's skin to measure the user's pulse wave; a communication unit receiving a signal from the sensor unit, processing it, and generating a transmission signal which is a transmitted signal; and an analysis unit receiving and analyzing the transmission signal; wherein the analysis unit analyzes the user's pulse wave information to determine whether the user has glaucoma.
이하에서는 첨부한 도면을 참조하여 본 발명을 설명하기로 한다. 그러나 본 발명은 여러 가지 상이한 형태로 구현될 수 있으며, 따라서 여기에서 설명하는 실시 예로 한정되는 것은 아니다. 그리고 도면에서 본 발명을 명확하게 설명하기 위해서 설명과 관계없는 부분은 생략하였으며, 명세서 전체를 통하여 유사한 부분에 대해서는 유사한 도면 부호를 붙였다.Hereinafter, the present invention will be described with reference to the attached drawings. However, the present invention can be implemented in various different forms, and therefore, it is not limited to the embodiments described herein. In addition, in order to clearly describe the present invention in the drawings, parts that are not related to the description are omitted, and similar parts are assigned similar drawing reference numerals throughout the specification.
명세서 전체에서, 어떤 부분이 다른 부분과 "연결(접속, 접촉, 결합)"되어 있다고 할 때, 이는 "직접적으로 연결"되어 있는 경우뿐 아니라, 그 중간에 다른 부재를 사이에 두고 "간접적으로 연결"되어 있는 경우도 포함한다. 또한 어떤 부분이 어떤 구성요소를 "포함"한다고 할 때, 이는 특별히 반대되는 기재가 없는 한 다른 구성요소를 제외하는 것이 아니라 다른 구성요소를 더 구비할 수 있다는 것을 의미한다.Throughout the specification, when a part is said to be "connected (connected, contacted, joined)" to another part, this includes not only the case where it is "directly connected" but also the case where it is "indirectly connected" with another member in between. Also, when a part is said to "include" a certain component, this does not mean that other components are excluded, unless otherwise specifically stated, but that other components can be included.
본 명세서에서 사용한 용어는 단지 특정한 실시 예를 설명하기 위해 사용된 것으로, 본 발명을 한정하려는 의도가 아니다. 단수의 표현은 문맥상 명백하게 다르게 뜻하지 않는 한, 복수의 표현을 포함한다. 본 명세서에서, "포함하다" 또는 "가지다" 등의 용어는 명세서상에 기재된 특징, 숫자, 단계, 동작, 구성요소, 부품 또는 이들을 조합한 것이 존재함을 지정하려는 것이지, 하나 또는 그 이상의 다른 특징들이나 숫자, 단계, 동작, 구성요소, 부품 또는 이들을 조합한 것들의 존재 또는 부가 가능성을 미리 배제하지 않는 것으로 이해되어야 한다.The terminology used herein is only used to describe particular embodiments and is not intended to limit the present invention. The singular expression includes the plural expression unless the context clearly indicates otherwise. As used herein, the terms "comprises" or "has" and the like are intended to specify the presence of a feature, number, step, operation, component, part or combination thereof described in the specification, but should be understood to not exclude in advance the possibility of the presence or addition of one or more other features, numbers, steps, operations, components, parts or combinations thereof.
이하, 첨부된 도면을 참고하여 본 발명에 대하여 상세히 설명하기로 한다.Hereinafter, the present invention will be described in detail with reference to the attached drawings.
도 1은 본 발명의 일 실시 예에 따른 웨어러블 장치와 충전기에 대한 모식도이고, 도 2는 본 발명의 일 실시 예에 따른 웨어러블 장치의 구성에 대한 모식도이다. 여기서, 도 1의 (a)는 본 발명의 웨어러블 장치에 대한 모식도이고, 도 1의 (b)는 본 발명의 충전기에 대한 모식도이다.FIG. 1 is a schematic diagram of a wearable device and a charger according to an embodiment of the present invention, and FIG. 2 is a schematic diagram of the configuration of a wearable device according to an embodiment of the present invention. Here, (a) of FIG. 1 is a schematic diagram of a wearable device of the present invention, and (b) of FIG. 1 is a schematic diagram of a charger of the present invention.
도 1과 도 2에서 보는 바와 같이, 본 발명의 웨어러블 장치는, 링 형상을 구비하고 내부 공간을 구비하는 하우징(160); 하우징(160)에 결합되고, 사용자의 피부와 접촉하여 사용자의 맥파를 측정하는 센서부(110); 센서부(110)의 신호를 전달받아 처리하여 송신되는 신호인 송신신호를 생성하는 통신부(130); 및 송신신호를 전달받아 분석하는 분석부(120);를 포함한다. 그리고, 분석부(120)에서는, 사용자의 맥파 정보를 분석하여 사용자의 녹내장의증을 판단할 수 있다.As shown in FIGS. 1 and 2, the wearable device of the present invention includes a housing (160) having a ring shape and an internal space; a sensor unit (110) coupled to the housing (160) and in contact with the user's skin to measure the user's pulse wave; a communication unit (130) that receives and processes a signal from the sensor unit (110) to generate a transmission signal, which is a transmitted signal; and an analysis unit (120) that receives and analyzes the transmission signal. In addition, the analysis unit (120) can analyze the user's pulse wave information to determine the user's glaucoma symptoms.
하우징(160)은 링의 형상을 구비하여 사용자의 손가락에 착용 가능하며, 이에 따라 하우징(160)의 내측면은 사용자의 손가락 피부와 접촉 가능할 수 있다. 외부로 노출되는 하우징(160)의 외부면은 티타늄, 스테인리스스틸(SUS)과 같은 금속 소재로 형성될 수 있으며, 하우징(160)의 내측면은 플라스틱과 같은 비금속으로 형성될 수 있다. 다만, 하우징(160)의 각 부위를 형성하는 소재가 이에 한정되는 것은 아니고, 다양한 소재가 이용될 수 있음은 물론이다.The housing (160) has a ring shape and can be worn on the user's finger, and accordingly, the inner surface of the housing (160) can be in contact with the user's finger skin. The outer surface of the housing (160) exposed to the outside can be formed of a metal material such as titanium or stainless steel (SUS), and the inner surface of the housing (160) can be formed of a non-metal such as plastic. However, the material forming each part of the housing (160) is not limited thereto, and it goes without saying that various materials can be used.
본 발명의 웨어러블 장치는, 분석부(120)로부터 작동신호를 전달받아 사용자의 피부에 진동을 전달함으로써 사용자에게 건강 이상 신호를 전달하는 진동부(140)를 더 포함할 수 있다.The wearable device of the present invention may further include a vibration unit (140) that receives an operating signal from an analysis unit (120) and transmits vibration to the user's skin to transmit a health abnormality signal to the user.
구체적으로, 분석부(120)에서 하기와 같은 과정에 의해 사용자가 녹내장의증을 갖게되는 것으로 판단되는 경우, 분석부(120)는 진동부(140)로 작동신호를 전달하게 되고, 진동부(140)에서는 이와 같은 작동신호에 반응하여 진동을 생성함으로써 진동부(140)에서 사용자의 피부로 진동이 전달되며, 이에 의해 사용자는 자신에게 녹내장의증 발생함을 인지할 수 있다.Specifically, when the analysis unit (120) determines that the user has glaucoma through the following process, the analysis unit (120) transmits an operating signal to the vibration unit (140), and the vibration unit (140) generates vibration in response to the operating signal, so that the vibration is transmitted from the vibration unit (140) to the user's skin, and thereby the user can recognize that he or she has glaucoma.
본 발명의 웨어러블 장치는, 하우징(160)의 내부 공간에 형성되고, 센서부(110)와 사용자의 피부가 밀착되도록 하며 진동부(140)와 사용자의 피부가 밀착되도록 하는 탄성부를 더 포함할 수 있다.The wearable device of the present invention may further include an elastic member formed in the internal space of the housing (160) to allow the sensor unit (110) to come into close contact with the user's skin and to allow the vibrating unit (140) to come into close contact with the user's skin.
탄성부는, 탄성을 구비하고 하우징(160)의 내부 공간에 형성되며 센서부(110)와 결합하여 센서부(110)를 하우징(160)의 중심 방향으로 가압하는 제1탄성체(151) 및, 탄성을 구비하고 하우징(160)의 내부 공간에 형성되며 진동부(140)와 결합하여 진동부(140)를 하우징(160)의 중심 방향으로 가압하는 제2탄성체(152)를 구비할 수 있다.The elastic member may include a first elastic body (151) that has elasticity and is formed in the internal space of the housing (160) and is combined with the sensor member (110) to press the sensor member (110) toward the center of the housing (160), and a second elastic body (152) that has elasticity and is formed in the internal space of the housing (160) and is combined with the vibrating member (140) to press the vibrating member (140) toward the center of the housing (160).
도 2에서 보는 바와 같이, 센서부(110)의 일 부위는 하우징(160)의 내측면 상에 돌출되어 있고, 진동부(140)의 일 부위도 하우징(160)의 내측면 상에 돌출되어 있을 수 있다. As shown in Fig. 2, a portion of the sensor portion (110) may protrude on the inner surface of the housing (160), and a portion of the vibrating portion (140) may also protrude on the inner surface of the housing (160).
그리고, 사용자의 손가락이 하우징(160)에 끼워지는 경우, 사용자의 손가락 피부가 센서부(110)의 돌출 부위와 진동부(140)의 돌출 부위 각각을 가압하게 되고, 동시에 손가락의 가압력에 대응하는 제1탄성체(151)의 가압력과 제2탄성체(152)의 가압력 각각이 센서부(110)와 진동부(140)와 전달되어, 센서부(110)와 진동부(140) 각각이 사용자 손가락의 피부에 밀착될 수 있다.And, when the user's finger is inserted into the housing (160), the skin of the user's finger presses the protruding portion of the sensor portion (110) and the protruding portion of the vibrating portion (140), respectively, and at the same time, the pressing force of the first elastic body (151) and the pressing force of the second elastic body (152), which correspond to the pressing force of the finger, are transmitted to the sensor portion (110) and the vibrating portion (140), respectively, so that the sensor portion (110) and the vibrating portion (140) can be in close contact with the skin of the user's finger.
이에 따라, 사용자의 손가락에 대한 진동부(140)의 진동 전달 효율이 증대되고, 센서부(110)가 사용자의 손가락 피부 하 혈관의 맥파를 측정 시 맥파 측정 정밀도 및 감도 등이 향상될 수 있다.Accordingly, the vibration transmission efficiency of the vibration unit (140) to the user's finger is increased, and the pulse measurement accuracy and sensitivity, etc., when the sensor unit (110) measures the pulse of the blood vessels under the skin of the user's finger can be improved.
본 발명의 웨어러블 장치는, 하우징(160)의 내부 공간에 형성되고, 센서부(110)와 통신부(130) 및 분석부(120)로 전기를 공급하는 배터리(170)를 더 포함할 수 있다. 그리고, 배터리(170)로부터 진동부(140)로 전기가 공급될 수 있다. 이와 같은 배터리(170)는 충전식으로 형성될 수 있으며, 상기된 각각의 구성으로 전기를 공급하여 작동시킬 수 있다.The wearable device of the present invention may further include a battery (170) formed in the internal space of the housing (160) and supplying electricity to the sensor unit (110), the communication unit (130), and the analysis unit (120). In addition, electricity may be supplied from the battery (170) to the vibrating unit (140). Such a battery (170) may be formed as a rechargeable type and may operate by supplying electricity to each of the above-described components.
분석부(120)는, 하우징(160)의 내부 공간 또는 하우징(160)의 외부에 형성될 수 있다. 도 2에서는 분석부(120)가 하우징(160)의 내부 공간에 형성되는 사항을 나타내고 있는데, 분석부(120)는 하우징(160)의 외부에 형성될 수도 있다. 구체적으로, 분석부(120)가 컴퓨터, 스마트폰, 태블릿PC, 스마트워치 등의 외부 전자기기에 설치되어 동일한 기능을 수행할 수도 있다.The analysis unit (120) may be formed in the internal space of the housing (160) or on the outside of the housing (160). In FIG. 2, the analysis unit (120) is shown to be formed in the internal space of the housing (160), but the analysis unit (120) may also be formed on the outside of the housing (160). Specifically, the analysis unit (120) may be installed in an external electronic device such as a computer, a smartphone, a tablet PC, or a smartwatch to perform the same function.
도 3은 본 발명의 일 실시 예에 따른 분석부(120)의 혈압 측정 과정에 대한 순서도이고, 도 4는 본 발명의 일 실시 예에 따른 광혈류측정 센서에 의한 측정 그래프이다. 도 4에서, 가로축은 감지 횟수이고 세로축은 광혈류측정(PPG: Photo-PlethysmoGraphy) 센서에 의한 감지 강도 값(감지 강도 최대값 대비 무차원수)이다.Fig. 3 is a flow chart of a blood pressure measurement process of an analysis unit (120) according to an embodiment of the present invention, and Fig. 4 is a measurement graph by a photoplethysmography sensor according to an embodiment of the present invention. In Fig. 4, the horizontal axis is the number of detections and the vertical axis is a detection intensity value (dimensionless number compared to the maximum detection intensity value) by a photoplethysmography (PPG) sensor.
도 3에서 보는 바와 같이, 사용자의 혈압 측정을 위하여, 분석부(120)에서는, 맥파 측정 시 나타나는 1차 피크(primary peak)와 2차 피크(secondary peak) 사이의 시간차를 측정하는 피크측정단계(S111); 사용자의 신장을 선택하는 신장선택단계(S112); SI값을 계산하는 SI계산단계(S120); 및 SI값을 이용하여 사용자의 혈압 값을 도출하는 혈압측정단계(S130)가 수행될 수 있다.As shown in FIG. 3, in order to measure the user's blood pressure, the analysis unit (120) may perform a peak measurement step (S111) of measuring the time difference between the primary peak and the secondary peak that appear when measuring the pulse; a height selection step (S112) of selecting the user's height; an SI calculation step (S120) of calculating an SI value; and a blood pressure measurement step (S130) of deriving the user's blood pressure value using the SI value.
피크측정단계(S111)와 신장선택단계(S112)의 수행을 위해, 분석부(120)는, 맥파 정보를 이용하여 혈관강성도((Stiffness Index, SI)를 도출할 수 있다. 여기서, 혈관강성도(SI)는 하기된 [수학식 1]에 의해 계산될 수 있다.In order to perform the peak measurement step (S111) and the height selection step (S112), the analysis unit (120) can derive the vascular stiffness (Stiffness Index, SI) using the pulse wave information. Here, the vascular stiffness (SI) can be calculated by the following [Mathematical Formula 1].
[수학식 1][Mathematical Formula 1]
SI=h/ΔTSI=h/ΔT
여기서, SI는 혈관강성도((Stiffness Index, SI) 값이고, h는 사용자의 신장(Height)이며, ΔT는 사용자의 맥파 측정 시 나타나는 1차 피크(primary peak)와 2차 피크(secondary peak) 사이의 시간차이다.Here, SI is the vascular stiffness index (SI) value, h is the user's height, and ΔT is the time difference between the primary peak and the secondary peak that appear when measuring the user's pulse wave.
본 발명의 웨어러블 장치를 착용하는 사용자의 신장에 대한 정보는 사전에 분석부(120)에 저장되어 있을 수 있으며, 센서부(110)는, 광혈류측정(PPG: Photo-PlethysmoGraphy) 센서를 구비하여, 도 4에서 보는 바와 같이 센서부(110)에서는 시간에 따른 맥파의 1차 피크(primary peak)와 2차 피크(secondary peak) 각각을 지속적으로 감지할 수 있다.Information about the height of a user wearing the wearable device of the present invention may be stored in advance in the analysis unit (120), and the sensor unit (110) is equipped with a photoplethysmography (PPG: Photo-PlethysmoGraphy) sensor, so that, as shown in FIG. 4, the sensor unit (110) can continuously detect each of the primary peak and secondary peak of the pulse wave over time.
이 때, 맥파 그래프는, 한 주기의 파장(λ)을 구비하는 한 주기의 파동으로써의 단위 파동이 복수로 형성되는 파동에 대한 그래프이며, 각각의 단위 파동에는 1차 피크(도 4의 a)와 2차 피크(도 4의 b)가 있을 수 있다.At this time, the pulse graph is a graph of a wave formed by multiple unit waves as one-cycle waves having one-cycle wavelength (λ), and each unit wave may have a first peak (a in Fig. 4) and a second peak (b in Fig. 4).
그리고, 센서부(110)의 광혈류측정 센서는 지속적으로 맥파를 감지함으로써 사용자 맥파의 1차 피크와 2차 피크를 지속적으로 감지할 수 있으며, 분석부(120)에서는 이를 이용하여 상기와 같이 혈관강성도(SI)를 계산하여 시간에 따른 혈관강성도(SI) 값을 계산할 수 있다.In addition, the photoplethysmography sensor of the sensor unit (110) can continuously detect the first and second peaks of the user's pulse by continuously detecting the pulse wave, and the analysis unit (120) can use this to calculate the vascular stiffness (SI) as described above, thereby calculating the vascular stiffness (SI) value over time.
그리고, 분석부(120)는, 하기의 [수학식 2]에 의해 사용자의 혈관강성도 값을 이용하여 사용자의 혈압 값을 도출할 수 있다.And, the analysis unit (120) can derive the user's blood pressure value by using the user's blood vessel stiffness value by [Mathematical Formula 2] below.
[수학식 2][Mathematical formula 2]
BP=a*ln(SI)+bBP=a*ln(SI)+b
여기서, BP는 혈압(Blood Pressure), SI는 혈관강성도, a와 b 각각은 사용자별 미리 정해지는 상수이다. 본 발명의 웨어러블 장치의 사용자가 정해지면 사전에 본 발명의 웨어러블 장치로 SI값을 측정하고 외부의 기기로 사용자의 혈압을 측정하여 이에 대한 데이터를 분석부(120)에 입력할 수 있으며, 분석부(120)에서는 이와 같은 데이터를 이용하여 [수학식 2]의 a와 b 값 각각을 도출하고 이를 [수학식 2]의 상수로써 저장할 수 있다.Here, BP is blood pressure, SI is vascular stiffness, and a and b are each constants predetermined for each user. When a user of the wearable device of the present invention is determined, the SI value can be measured in advance using the wearable device of the present invention and the user's blood pressure can be measured using an external device, and the data on this can be input into the analysis unit (120). The analysis unit (120) can use this data to derive the a and b values of [Mathematical Formula 2], and store them as constants of [Mathematical Formula 2].
상기와 같이 분석부(120)에서 혈압이 측정될 수 있으며, 이와 같은 혈압은 SI값에 의해 도출되는 것으로써 시간에 따른 SI값의 변동에 따라 시간에 따른 사용자의 혈압 변동에 대해서도 도출될 수 있다. 이와 같은 혈압 변동이 하기의 평균동맥압(mean arterial pressure, MAP) 변동으로 측정될 수 있다. As described above, blood pressure can be measured in the analysis unit (120), and such blood pressure is derived by the SI value, and thus, the user's blood pressure fluctuations over time can also be derived according to the fluctuations in the SI value over time. Such blood pressure fluctuations can be measured as the mean arterial pressure (MAP) fluctuations below.
즉, 시간(hour) 단위로 복수의 맥박에 대한 평균동맥압을 측정하여 이에 대한 변동을 측정하고 이용할 수 있으며, 이에 대해서는 하기에 더 상세히 설명한다.That is, by measuring the mean arterial pressure for multiple pulses in units of hours, the fluctuations thereof can be measured and utilized, and this is explained in more detail below.
도 5 내지 도 7은 평균 안압과 평균동맥압 및 평균 안구관류압 각각에 대한 그래프이다.Figures 5 to 7 are graphs for mean intraocular pressure, mean arterial pressure, and mean ocular perfusion pressure, respectively.
여기서, 도 5는, 2명의 환자(Patient 1, Patient 2)에 대해 하루 중 소정의 측정 시간 동안 측정된 시간별 평균 안압(mean intraocular pressure, IOP)에 대한 그래프이고, 도 6은, 상기된 2명의 환자(Patient 1, Patient 2)에 대해 하루 중 소정의 측정 시간 동안 측정된 시간별 평균동맥압(mean arterial pressure, MAP)에 대한 그래프이며, 도 7은, 상기된 2명의 환자(Patient 1, Patient 2)에 대해 하루 중 소정의 측정 시간 동안 측정된 시간별 평균 안구관류압(mean ocular perfusion pressure, MOPP)에 대한 그래프이다.Here, FIG. 5 is a graph of the hourly mean intraocular pressure (IOP) measured during a given measurement time during a day for two patients (
도 5 내지 도 7 각각의 그래프에서, 가로축은 시간(Time)을 나타내고, 세로축은 각각 평균 안압(mean intraocular pressure, IOP), 평균동맥압(mean arterial pressure, MAP) 및 평균 안구관류압(mean ocular perfusion pressure, MOPP)을 나타낸다.In each of the graphs in FIGS. 5 to 7, the horizontal axis represents time, and the vertical axis represents mean intraocular pressure (IOP), mean arterial pressure (MAP), and mean ocular perfusion pressure (MOPP), respectively.
도 5에서 보는 바와 같이, 제1환자(Patient 1)의 그래프와 제2환자(Patient 2)의 그래프를 비교하면, 제1환자(Patient 1)의 평균 안압 변동(IOP fluctuation) 값이 더 큰 것을 확인할 수 있고, 제1환자(Patient 1)가 녹내장의증 보유로 판단될 수 있다. (IOP fluctuation 값이 5 초과인 경우를 녹내장의증 보유로 진단하는 경우)As shown in Figure 5, when comparing the graph of
도 6에서 보는 바와 같이, 제1환자(Patient 1)의 그래프와 제2환자(Patient 2)의 그래프를 비교하면, 해당 측정 시간 동안 평균동맥압 변동(MAP fluctuation)이 형성되고, 평균 안압 변동(IOP fluctuation)의 변동 폭 발생과 유사하게, 제1환자(Patient 1)의 평균동맥압 변동(MAP fluctuation)이 더 큰 것을 확인할 수 있다.(제1환자: 23.3, 제2환자: 11.3)As shown in Figure 6, when comparing the graphs of
이에 대해서는, 전산 혈압과 안압 사이의 연관성에 대한 실험적 측정에서, 수축기 혈압 10mmHg 상승 시 안압이 0.24mmHg 상승하고, 이완기 혈압 10mmHg 상승 시 안압이 0.4mmHg 상승하는 것으로 연관성(상관관계:0.94)을 확인할 수 있다.In this regard, in an experimental measurement of the relationship between computed blood pressure and intraocular pressure, it was confirmed that when systolic blood pressure increases by 10 mmHg, intraocular pressure increases by 0.24 mmHg, and when diastolic blood pressure increases by 10 mmHg, intraocular pressure increases by 0.4 mmHg, confirming the relationship (correlation: 0.94).
또한, 도 7에서 보는 바와 같이, 제1환자(Patient 1)의 그래프와 제2환자(Patient 2)의 그래프를 비교하면, 평균동맥압 변동(MAP fluctuation)의 그래프와 유사하게 평균 안구관류압 변동(MOPP fluctuation) 그래프가 형성되며, 평균 안압 변동(IOP fluctuation)의 변동 폭 발생과 유사하게, 제1환자(Patient 1)의 평균 안구관류압 변동(MOPP fluctuation)이 더 큰 것을 확인할 수 있다.(제1환자: 27.3, 제2환자: 7.3)In addition, as shown in Fig. 7, when comparing the graph of
상기와 같이, 환자별 평균 안압 변동(IOP fluctuation) 값의 경향이 환자별 평균동맥압 변동(MAP fluctuation) 값의 경향과 평균 안구관류압 변동(MOPP fluctuation) 값의 경향에 연관됨을 확인할 수 있다.As described above, it can be confirmed that the trend of the average intraocular pressure fluctuation (IOP fluctuation) value per patient is related to the trend of the average arterial pressure fluctuation (MAP fluctuation) value and the trend of the average ocular perfusion pressure fluctuation (MOPP fluctuation) value per patient.
즉, 사용자의 혈압 변동이 평균 안압 변동(IOP fluctuation)에 영향을 주고, 평균 안압 변동(IOP fluctuation)이 심한 환자가 녹내장 발병률이 높은 것, 즉, 녹내장의증을 보유한 것으로 진단에 활용할 수 있는 것이다.That is, the user's blood pressure fluctuation affects the average intraocular pressure fluctuation (IOP fluctuation), and patients with severe average intraocular pressure fluctuation (IOP fluctuation) have a high incidence of glaucoma, i.e., can be diagnosed as having symptoms of glaucoma.
상기와 같은 원리에 의해, 분석부(120)에서는, 측정 기간 내 사용자의 평균동맥압(Average mean arterial pressure, MAP) 변동 값이 소정의 값 이상인 경우 사용자가 녹내장의증이라고 판단할 수 있다.By the above principle, the analysis unit (120) can determine that the user has glaucoma if the average mean arterial pressure (MAP) fluctuation value of the user during the measurement period is greater than a predetermined value.
구체적으로, 분석부(120)에는 본 발명의 웨어러블 장치를 착용하는 사용자에 대해 기준이 되는 평균동맥압의 변동 값인 기준변동값이 저장되어 있으며, 상기와 같이 센서부(110)의 신호를 전달받아 사용자의 혈압 변동을 도출하는 분석부(120)는, 시간별 평균동맥압 변동 값을 지속적으로 측정할 수 있으며, 미리 설정된 측정 기간 내 시간별 평균동맥압 변동 값 측정 중 분석부(120)에서 사용자의 평균동맥압 변동 값이 기준변동값을 초과하는 것으로 분석되는 경우, 분석부(120)는 사용자에 녹내장의증이 발생한 것으로 판단할 수 있다.Specifically, the analysis unit (120) stores a reference fluctuation value, which is a fluctuation value of the mean arterial pressure that serves as a reference for a user wearing the wearable device of the present invention, and the analysis unit (120), which receives a signal from the sensor unit (110) as described above and derives the user's blood pressure fluctuation, can continuously measure the fluctuation value of the mean arterial pressure by hour, and if the analysis unit (120) analyzes that the user's fluctuation value of the mean arterial pressure exceeds the reference fluctuation value during the measurement of the fluctuation value of the mean arterial pressure by hour within a preset measurement period, the analysis unit (120) can determine that the user has glaucoma.
그리고, 분석부(120)에서 진동부(140)로 작동신호가 전달되어 진동부(140)가 작동하고, 진동부(140)의 진동이 사용자의 손가락으로 전달되어, 사용자는 본인에게 녹내장의증이 발생함을 확인할 수 있다.And, an operating signal is transmitted from the analysis unit (120) to the vibration unit (140), the vibration unit (140) operates, and the vibration of the vibration unit (140) is transmitted to the user's finger, so that the user can confirm that he or she has glaucoma.
상기와 같은 본 발명의 웨어러블 장치 및, 본 발명의 웨어러블 장치와 선택적으로 결합하여 충전을 수행하는 충전기를 포함하는 녹내장의증 모니터링 시스템이 형성될 수 있다.A glaucoma monitoring system can be formed, including a wearable device of the present invention as described above, and a charger that is selectively combined with the wearable device of the present invention to perform charging.
도 1의 (b)에서 보는 바와 같이, 충전기는, 본 발명의 웨어러블 장치와 인접 시 무선으로 배터리(170)에 대한 충전을 수행하는 몸체(210); 및 몸체(210)의 상부면으로부터 돌출되어 형성되고 본 발명의 웨어러블 장치가 끼워지는 거치체(220);를 포함할 수 있다.As shown in (b) of Fig. 1, the charger may include a body (210) that wirelessly charges a battery (170) when adjacent to the wearable device of the present invention; and a holder (220) that is formed by protruding from the upper surface of the body (210) and into which the wearable device of the present invention is fitted.
그리고, 몸체(210)에는 전원케이블과 연결되어 전원으로부터 전기를 전달받는 단자(211)가 형성되고, 거치체(220)의 상부면에는 배터리(170)의 충전 중 여부, 배터리(170)의 충전 완료 여부 등(각각 색으로 구분)을 광으로 표시하는 표시체(221)가 형성될 수 있다.In addition, a terminal (211) connected to a power cable and receiving electricity from a power source may be formed on the body (210), and an indicator (221) may be formed on the upper surface of the holder (220) to indicate with light whether the battery (170) is being charged, whether the battery (170) is fully charged, etc. (each distinguished by color).
그리고, 녹내장의증 모니터링 시스템은, 본 발명의 웨어러블 장치의 외부에 형성되어 복수의 웨어러블 장치로부터 정보를 전달받고, 해당 정보의 수집 분석을 수행하는 중앙처리부를 더 포함할 수 있다.In addition, the glaucoma monitoring system may further include a central processing unit formed outside the wearable device of the present invention to receive information from a plurality of wearable devices and perform collection and analysis of the information.
중앙처리부에서는 복수의 웨어러블 장치의 정보를 이용하여 각각의 환자군으로 사용자들을 구분할 수 있고, 각각의 환자군에서의 평균동맥압 변동(MAP fluctuation)과 평균 안압 변동(IOP fluctuation) 및 평균 안구관류압 변동 평균 안구관류압 변동 각각의 경향에 대한 분석을 수행하고, 중앙처리부에 입력된 안압에 따른 환자 진단 데이터 등을 이용하여, 각각의 환자군에서 진단 기준이 되는 상기의 기준변동값을 도출할 수 있다.The central processing unit can use information from multiple wearable devices to classify users into each patient group, and perform analysis on trends in mean arterial pressure fluctuation (MAP fluctuation), mean intraocular pressure fluctuation (IOP fluctuation), and mean ocular perfusion pressure fluctuation in each patient group, and use patient diagnosis data according to IOP input into the central processing unit to derive the above-mentioned reference fluctuation value that serves as a diagnostic criterion in each patient group.
여기서, 환자군 구분을 위해서, 남녀 성별, 환자 나이, 환자 신장과 몸무게 와 같은 환자 정보 등을 이용할 수 있다. 중앙처리부는 분석부(120)로부터 착용 사용자의 정보도 전달받을 수 있으며, 소정의 환자군에 사용자가 속하는 경우, 해당 환자군에 적합한 기준변동값을 선택하여 분석부(120)로 전달하고, 분석부(120)는 해당 기준변동값을 이용하여 상기와 같은 분석 판단을 수행할 수 있다.Here, in order to classify patient groups, patient information such as male and female gender, patient age, patient height and weight, etc. can be used. The central processing unit can also receive information on the wearing user from the analysis unit (120), and if the user belongs to a certain patient group, selects a standard change value suitable for the patient group and transmits it to the analysis unit (120), and the analysis unit (120) can perform the above analysis judgment using the standard change value.
상기와 같은 본 발명의 웨어러블 장치를 이용하는 경우, 사용자의 맥파 측정으로 평균동맥압 변동(MAP fluctuation)을 도출하고, 이와 같은 평균동맥압 변동 정보로 사용자의 녹내장의증 발병 여부를 판단하므로, 측정이 신속함과 동시에 녹내장의증 발병 여부를 용이하게 판단 분석할 수 있다.When using the wearable device of the present invention as described above, the mean arterial pressure fluctuation (MAP fluctuation) is derived by measuring the user's pulse, and whether the user has glaucoma is determined based on this MAP fluctuation information, so that the measurement is quick and at the same time, the onset of glaucoma can be easily determined and analyzed.
또한, 본 발명의 웨어러블 장치를 이용하는 경우, 항상 사용자의 손가락에 본 발명의 웨어러블 장치를 착용하여 실시간으로 맥파 측정 등이 수행되며, 질병 발생에 대한 지속적인 분석이 수행되므로, 질병 진단의 정확도와 진단 속도 등이 향상될 수 있다.In addition, when using the wearable device of the present invention, the wearable device of the present invention is always worn on the user's finger, and pulse measurement, etc. is performed in real time, and continuous analysis of disease occurrence is performed, so that the accuracy and speed of disease diagnosis, etc. can be improved.
이하, 본 발명의 웨어러블 장치를 이용한 녹내장의증 모니터링 방법에 대해 설명하기로 한다.Hereinafter, a method for monitoring glaucoma symptoms using the wearable device of the present invention will be described.
먼저, 제1단계에서, 센서부(110)에서 사용자의 맥파를 감지할 수 있다. 그리고, 제2단계에서, 센서부(110)로부터 분석부(120)로 맥파 정보가 전달되고, 분석부(120)에서 맥파 정보를 이용하여 혈관강성도((Stiffness Index, SI)를 도출할 수 있다.First, in the first step, the sensor unit (110) can detect the user's pulse wave. Then, in the second step, the pulse wave information is transmitted from the sensor unit (110) to the analysis unit (120), and the analysis unit (120) can derive the blood vessel stiffness (Stiffness Index, SI) using the pulse wave information.
다음으로, 제3단계에서는, 분석부(120)에서, 사용자의 혈관강성도 값을 이용하여 사용자의 혈압 값을 도출하고, 측정 기간 내 시간별 사용자의 평균동맥압(Average mean arterial pressure, MAP) 값을 도출할 수 있다. 그 후, 제4단계에서는, 분석부(120)에서, 사용자의 평균동맥압 변동 값이 소정의 값 이상인 경우 사용자가 녹내장의증이라고 판단할 수 있다.Next, in the third step, the analysis unit (120) can derive the user's blood pressure value using the user's vascular stiffness value, and derive the user's average mean arterial pressure (MAP) value by hour within the measurement period. Then, in the fourth step, the analysis unit (120) can determine that the user has glaucoma if the user's average arterial pressure fluctuation value is greater than a predetermined value.
본 발명의 녹내장의증 모니터링 방법에 대한 나머지 상세한 사항은 상기된 본 발명의 웨어러블 장치에 대한 기재 사항과 동일하다.The remaining details of the glaucoma monitoring method of the present invention are the same as those described for the wearable device of the present invention described above.
전술한 본 발명의 설명은 예시를 위한 것이며, 본 발명이 속하는 기술분야의 통상의 지식을 가진 자는 본 발명의 기술적 사상이나 필수적인 특징을 변경하지 않고서 다른 구체적인 형태로 쉽게 변형이 가능하다는 것을 이해할 수 있을 것이다. 그러므로 이상에서 기술한 실시 예들은 모든 면에서 예시적인 것이며 한정적이 아닌 것으로 이해해야만 한다. 예를 들어, 단일형으로 설명되어 있는 각 구성 요소는 분산되어 실시될 수도 있으며, 마찬가지로 분산된 것으로 설명되어 있는 구성 요소들도 결합된 형태로 실시될 수 있다. The above description of the present invention is for illustrative purposes, and those skilled in the art will understand that the present invention can be easily modified into other specific forms without changing the technical idea or essential features of the present invention. Therefore, it should be understood that the embodiments described above are exemplary in all respects and not restrictive. For example, each component described as a single component may be implemented in a distributed manner, and likewise, components described as distributed may be implemented in a combined form.
본 발명의 범위는 후술하는 특허청구범위에 의하여 나타내어지며, 특허청구범위의 의미 및 범위 그리고 그 균등 개념으로부터 도출되는 모든 변경 또는 변형된 형태가 본 발명의 범위에 포함되는 것으로 해석되어야 한다.The scope of the present invention is indicated by the claims described below, and all changes or modifications derived from the meaning and scope of the claims and their equivalent concepts should be interpreted as being included in the scope of the present invention.
<부호의 설명><Explanation of symbols>
110: 센서부110: Sensor section
120: 분석부120: Analysis Department
130: 통신부130: Communications Department
140: 진동부140: Vibration section
151: 제1탄성체151: First elastic body
152: 제2탄성체152: Second elastic body
160: 하우징160: Housing
170: 배터리170: Battery
210: 몸체210: Body
211: 단자211: Terminal
220: 거치체220: The stand
221: 표시체 221: Display
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Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2017514657A (en) * | 2014-05-01 | 2017-06-08 | ニューミトラ インク.Neumitra Inc. | Wearable electronics |
| KR20180066769A (en) * | 2016-12-09 | 2018-06-19 | 엘지전자 주식회사 | Mobile device |
| JP2021168913A (en) * | 2020-04-09 | 2021-10-28 | インスティトゥト・ヘミー・ビオオルガニチネイ・ペアエヌInstytut Chemii Bioorganicznej PAN | Method for creating predictive model for predicting glaucoma risk in subject, method for determining glaucoma risk in subject using such predictive model, device for predicting glaucoma risk in subject, computer program and computer readable medium |
| US20230181112A1 (en) * | 2021-12-13 | 2023-06-15 | Hhid, Llc | Wearable ring-type sensor devices for monitoring health and wellness conditions |
| CN115281621A (en) * | 2022-09-29 | 2022-11-04 | 首都医科大学附属北京同仁医院 | Wearable detection method and device for glaucoma disease risk |
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| Publication number | Publication date |
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| KR20250035921A (en) | 2025-03-13 |
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