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WO2025048427A1 - Bandelette de diagnostic in vitro - Google Patents

Bandelette de diagnostic in vitro Download PDF

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Publication number
WO2025048427A1
WO2025048427A1 PCT/KR2024/012683 KR2024012683W WO2025048427A1 WO 2025048427 A1 WO2025048427 A1 WO 2025048427A1 KR 2024012683 W KR2024012683 W KR 2024012683W WO 2025048427 A1 WO2025048427 A1 WO 2025048427A1
Authority
WO
WIPO (PCT)
Prior art keywords
channel
sub
vitro diagnostic
deployment
development
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/KR2024/012683
Other languages
English (en)
Korean (ko)
Inventor
조영식
박오준
양정아
김익록
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SD Biosensor Inc
Original Assignee
SD Biosensor Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020240113293A external-priority patent/KR20250030935A/ko
Application filed by SD Biosensor Inc filed Critical SD Biosensor Inc
Publication of WO2025048427A1 publication Critical patent/WO2025048427A1/fr
Pending legal-status Critical Current
Anticipated expiration legal-status Critical

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers

Definitions

  • the present invention relates to an in vitro diagnostic strip, and more particularly, to an in vitro diagnostic strip having a channel structure capable of collecting a sample for in vitro diagnosis and facilitating the flow of the sample.
  • in vitro diagnostic technology is a technology that rapidly diagnoses diseases outside the body using substances derived from the human body, such as blood, feces, body fluids, and saliva, and is playing an important role in clinical decision-making and becoming an essential and specialized element in patient treatment.
  • An in vitro diagnostic device using this is a medical device used for testing using specimens such as tissue, blood, and urine collected from the human body for the purposes of diagnosing and prognosing diseases, assessing health status, assessing the effectiveness of disease treatment, and preventing diseases. It refers to a device including reagents used, and since the diagnosis is made outside the human body, it causes less burden on the body than medical devices that require insertion into the human body.
  • One embodiment of the present invention provides an in vitro diagnostic strip that prevents a sample flowing into a sub-development channel from slowing down and allows smooth flow of the sample through capillary phenomenon by forming a variable flow path portion in the sub-development channel whose cross-sectional area of the flow narrows.
  • one embodiment of the present invention provides an in vitro diagnostic strip that can block a sample from flowing back into a sub-development channel when the amount of sample is large or the flow rate is excessively fast by forming a blocking flow portion in the sub-development channel.
  • an in vitro diagnostic strip comprises: a strip body into which a specimen is introduced; a main development channel formed on the strip body and through which a specimen introduced into the strip body is developed; and a plurality of sub-development channels branching out and extending from one side of the main development channel and through which the specimen is developed, wherein a variable flow path section having at least a portion of a reduced flow cross-sectional area may be formed in the sub-development channel.
  • variable flow section can be formed such that the flow cross-sectional area narrows from upstream to downstream.
  • the above variable flow section can be formed so that the flow cross-sectional area is constant from upstream to downstream.
  • variable flow section can be positioned downstream from the sub-deployment channel.
  • An inspection hole through which light passes can be formed at the downstream end of the above sub-deployment channel.
  • the above variable euro portion can be positioned adjacent to the inspection hole.
  • the above sub-deployment channels may be extended in a plurality of vertical directions on both sides of the above main deployment channel.
  • the above sub-deployment channels extend in multiple numbers from both sides of the above main deployment channel, and the sub-deployment channels arranged on one side of the above main deployment channel and the sub-deployment channels arranged on the other side may be arranged in an alternating manner with each other.
  • a first vent hole communicating with outside air may be formed at an end of the above main deployment channel.
  • the width of the above main deployment channel can be formed to be larger than the width of the above sub deployment channel.
  • a vent channel is formed between the end of the main deployment channel and the first vent hole, and the vent channel can be formed to be smaller than the width of the sub deployment channel.
  • a second vent hole communicating with the outside air may be formed at each end of the above sub-deployment channel.
  • the above strip body may include a gripping portion in which a specimen injection hole into which the specimen is injected is formed; and a film-shaped channel portion coupled to one side of the gripping portion and in which the main expansion channel and the sub expansion channel are formed.
  • the above channel section may include a channel film in which the main deployment channel and the sub-deployment channel are formed; and a first cover film and a second cover film attached to the upper and lower surfaces of the channel film, respectively.
  • the above channel section may include a channel film in which the main deployment channel and the sub-deployment channel are formed; a first cover film attached to an upper surface of the channel film and in which the main deployment channel and the sub-deployment channel are formed; and a second cover film attached to a lower surface of the channel film, respectively.
  • an in vitro diagnostic strip comprises: a strip body into which a specimen is introduced; a main expansion channel formed on the strip body and through which a specimen introduced into the strip body is developed; a plurality of sub expansion channels branching out and extending from one side of the main expansion channel and through which the specimen is developed; and a test hole disposed at a downstream end of the sub expansion channel and through which light is transmitted, wherein a blocking channel portion for changing the flow direction of the specimen is formed in the sub expansion channel, thereby blocking the specimen from flowing in the opposite direction in the test hole.
  • the above blocking euro section can be placed at the downstream end of the sub-deployment channel.
  • the above blocking euro portion can be arranged perpendicular to the flow direction of the sub-deployment channel.
  • a connecting flow path section can be formed at each of the upstream and downstream ends of the above-mentioned blocking flow path section.
  • the above connecting portion may be formed to have a narrower width than the sub-deployment channel.
  • the points at which the above connecting portion is connected to the above blocking portion may be positioned differently in the width direction.
  • the above sub-development channel may be provided with a variable flow path section in which at least some of the flow cross-sectional area is reduced.
  • variable flow section can be formed such that the flow cross-sectional area narrows from upstream to downstream.
  • the above variable flow section can be formed so that the flow cross-sectional area is constant from upstream to downstream.
  • the above blocking flow path section may be arranged downstream of the sub-deployment channel, and the variable flow path section may be arranged upstream of the blocking flow path section.
  • the sample flowing into the sub-development channel is prevented from slowing down, and the flow of the sample can be smoothly achieved through capillary phenomenon.
  • the present invention by forming a blocking flow path in the sub-deployment channel, it is possible to prevent the sample from flowing back into the sub-deployment channel due to a large amount of sample or an excessively fast flow rate.
  • FIG. 1 is a perspective view illustrating an in vitro diagnostic strip according to one embodiment of the present invention.
  • FIG. 2 is an exploded perspective view illustrating a channel portion of an in vitro diagnostic strip according to one embodiment of the present invention.
  • FIG. 3 is an enlarged plan view illustrating one embodiment in which a variable flow path portion is formed in the channel portion of an in vitro diagnostic strip according to the present invention.
  • FIG. 4 is an enlarged plan view illustrating another embodiment in which a variable flow path portion is formed in the channel portion of an in vitro diagnostic strip according to the present invention.
  • FIG. 6 is an enlarged plan view illustrating one embodiment in which a blocking path portion is formed in the channel portion of an in vitro diagnostic strip according to the present invention.
  • FIG. 7 is an enlarged plan view illustrating another embodiment in which a blocking path portion is formed in the channel portion of an in vitro diagnostic strip according to the present invention.
  • FIG. 8 is an enlarged plan view illustrating another embodiment in which a blocking path portion is formed in the channel portion of an in vitro diagnostic strip according to the present invention.
  • FIG. 9 is an enlarged plan view showing one embodiment of the variable flow path shown in FIG. 3 combined with one embodiment of the blocking flow path shown in FIG. 6.
  • FIG. 10 is an enlarged plan view showing one embodiment of the variable flow path shown in FIG. 4 combined with one embodiment of the blocking flow path shown in FIG. 6.
  • FIG. 11 is an enlarged plan view showing one embodiment of the variable flow path shown in FIG. 5 combined with one embodiment of the blocking flow path shown in FIG. 6.
  • first, second, etc. may be used to describe various components, but the components should not be limited by the terms. The terms are used only to distinguish one component from another.
  • each component when described as being formed or arranged “above or below” each component, above or below includes not only the case where the two components are in direct contact with each other, but also the case where one or more other components are formed or arranged between the two components.
  • it when expressed as “above or below,” it can include the meaning of the downward direction as well as the upward direction based on one component.
  • FIG. 1 is a perspective view illustrating an in vitro diagnostic strip according to one embodiment of the present invention
  • FIG. 2 is an exploded perspective view illustrating a channel portion of an in vitro diagnostic strip according to one embodiment of the present invention.
  • an in vitro diagnostic strip includes a strip body (10), a main development channel (212, 232) formed on the strip body (10) and through which a sample introduced into the strip body (10) is developed, and a plurality of sub-development channels (216, 235) branched and extended from one side of the main development channel (212, 232) and through which the sample is developed, and a variable flow path portion (300) having at least a portion of a flow cross-sectional area reduced may be formed in the sub-development channel (216, 235).
  • the strip body (10) forms the overall appearance of the in vitro diagnostic strip and may be formed in a flat plate shape.
  • the strip body (10) may include a holding portion (100) in which a specimen injection hole (110) into which a specimen is injected is formed, and a film-shaped channel portion (200) coupled to one side of the holding portion (100) and in which the main development channel (212) and the sub development channel (216) are formed.
  • the strip body (10) includes a gripping portion (100) that a worker grips to insert into an in vitro diagnostic device, and a channel portion (200) that is coupled to one end of the gripping portion (100).
  • the gripping portion (100) may be made of a plastic material, and the channel portion (200) may be made in a film form.
  • a specimen input hole (110) is formed in the phage section (100), and the specimen input hole (110) is connected to the channel input hole (214), the first input hole (234), and the second input hole (244) formed in the channel section (200), respectively.
  • a specimen input into the specimen input hole (110) can be deployed along the main deployment channel (212) and the sub deployment channel (216) formed in the channel section (200).
  • the channel section (200) may include a channel film (210) in which the main deployment channel (212) and the sub-deployment channel (216) are formed, and cover films (230, 240) attached to the upper and lower surfaces of the channel film (210), respectively.
  • the cover films (230, 240) may include a first cover film (230) attached to the upper surface of the channel film (210) and a second cover film (240) attached to the lower surface of the channel film (210).
  • the first cover film (230) and the second cover film (240) may be attached to the upper and lower surfaces of the channel film (210) using a double-sided tape.
  • the channel section (200) is configured by attaching a cover film (230, 240) to the channel film (210), it is easy to form a main development channel (212) and a sub development channel (216), and a constant contact angle can be maintained.
  • the main deployment channel (212) and the sub-deployment channel (216) may be formed by being opened upwardly and downwardly on the channel film (210) that substantially constitutes the channel portion (200).
  • cover films (230, 240) are attached to the upper and lower surfaces of the channel film (210), respectively, to form the main deployment channel (212) and the sub-deployment channel (216).
  • the first cover film (230) may be formed with a main deployment channel (232) and a sub-deployment channel (235) corresponding to the main deployment channel (212) and the sub-deployment channel (216).
  • the main deployment channel (232) is a portion where a sample introduced into the strip body (10) is initially deployed, and may be formed to be long along the longitudinal direction of the channel portion (200).
  • a plurality of sub-deployment channels (235) are vertically extended on both sides of the main deployment channel (232) so that a sample can be deployed through them.
  • the main deployment channel (232) and the sub-deployment channel (235) are shown as being formed in the first cover film (230), but this is not limited thereto, and the main deployment channel (212) and the sub-deployment channel (216) may be formed only in the channel portion (200), and the first cover film (230) may be configured to cover this.
  • the main deployment channel (212) is a portion where the sample introduced into the strip body (10) is initially deployed, and may be formed long along the length of the channel portion (200).
  • a plurality of sub-deployment channels (216) extend vertically on both sides of the main deployment channel (212), and the sample may be deployed through these.
  • the sub-deployment channels (216) do not have to extend vertically on both sides of the main deployment channel (212), and may extend in an inclined direction.
  • a plurality of sub-deployment channels (216) may be formed at regular intervals along both sides of the main deployment channel (212), and the sub-deployment channels (216) arranged on one side and the other side may be arranged alternately. That is, the sub-deployment channels (216) arranged on the other side may be arranged alternately between each of the sub-deployment channels (216) arranged on one side.
  • the sub-deployment channels (216) are arranged alternately on both sides in this way, the specimen may be smoothly introduced into each sub-deployment channel (216).
  • An inspection hole (218) into which light of an in vitro diagnostic device is irradiated may be formed in the sub-deployment channel (216).
  • the inspection hole (218) is a portion through which light is transmitted from an optical module mounted on the in vitro diagnostic device, and a diagnosis can be made by determining the condition of a specimen through light transmission. Since the inspection hole (218) is formed in the sub-deployment channel (216), the operator can make various types of diagnoses from the specimen detected through each inspection hole (218).
  • a variety of targets can be detected as many as the number of inspection holes (218) using one in vitro diagnostic device, and each inspection hole (218) can be used to detect the same target or different targets.
  • the first cover film (230) and the second cover film (240) are formed with first cover inspection holes (236) and second cover inspection holes (246) respectively having openings corresponding to a plurality of inspection holes (218) so that light can be transmitted.
  • the worker can easily check whether the reagent has been spread throughout the channel section (200) by checking from the inspection hole (218) formed closest to the first vent hole (220).
  • a first vent hole (220) communicating with the outside air is formed at an end of the main deployment channel (212).
  • the first vent hole (220) is formed at an end of the main deployment channel (212) so that the sample can flow well through the main deployment channel (212) and the sub-deployment channel (216) by capillary action.
  • a second vent hole (222) communicating with the outside air is formed at an end of the sub-deployment channel (216).
  • the second vent hole (222) like the first vent hole (220), also allows the sample to flow well through the capillary action.
  • the first vent hole (220) and the second vent hole (222) may be formed to communicate with the first cover vent hole (237) and the second cover vent hole (238) formed in the first cover film (230), respectively.
  • the first cover vent hole (237) and the second cover vent hole (238) may be formed only in the first cover film (230), and the first cover vent hole (237) and the second cover vent hole (238) may be formed in a long slit shape so as to communicate with the first vent hole (220) and the second vent hole (222) arranged on the inside.
  • a vent channel (224) having a narrow path can be formed between the end of the main deployment channel (212) and the first vent hole (220).
  • the vent channel (224) is formed to be smaller than the width of the main deployment channel (212) so that the capillary phenomenon can occur easily.
  • the main deployment channel (212) is formed to be larger than the width of the sub-deployment channel (216) and the vent channel (224), and the sub-deployment channel (216) is formed to be larger than the width of the vent channel (224).
  • the widths of the channels may be formed to be large in the order of the main deployment channel (212), the sub-deployment channel (216), and the vent channel (224).
  • 16 sub-deployment channels (216) are formed in the main deployment channel (212), and accordingly, 16 inspection holes (218) can also be formed.
  • 16 inspection holes (218) and sub-deployment channels (216) connecting the inspection holes (218) and the main deployment channel (212) can be provided on one side of the main deployment channel (212).
  • eight inspection holes (218) and sub-deployment channels (216) can be provided on the other side of the main deployment channel (212).
  • an enzyme for conducting an examination may be accommodated or applied in the first cover inspection hole (236) and the second cover inspection hole (246).
  • the enzyme bilirubin oxidase may be accommodated or applied, but is not limited thereto.
  • the examination may be conducted by reacting with the injected specimen and the enzyme.
  • a hydrophilic coating layer may be formed in the portion of the cover film (230, 240) where the main development channel (212) and the sub development channel (216) are formed, so as to implement a capillary function.
  • the cover film (230, 240) may be made of a hydrophilic material or the portion may be hydrophilically treated (e.g., by applying a chemical reagent). If the cover film (230, 240) is not hydrophilically treated, the capillary phenomenon function deteriorates, slowing down the sample injection speed, so that normal sample development and measurement may not be possible.
  • the variable flow path (300) is a part formed to prevent the sample flowing from the main development channel (232) to the sub development channel (235) from slowing down and to effectively suck the sample up to the first cover inspection hole (236) through the capillary phenomenon. That is, the flow of the sample can be slowed down in the sub development channel (235) branched from the main development channel (232) because the flow direction is changed to a vertical direction in the main development channel (232). Accordingly, the sample can stagnate in the sub development channel (235), but when the variable flow path (300) is formed, the flow of the sample can be smoothly achieved through the capillary phenomenon.
  • variable flow path section (300) narrows the width of a portion of the sub-development channel (235) formed in a straight line, thereby reducing the flow cross-sectional area.
  • variable flow path section (300) may narrow both sides of the sub-development channel (235) to form an overall narrow width.
  • variable flow path (300) may be formed so that the flow cross-sectional area is constant from upstream to downstream as shown in the drawing.
  • upstream means the point where the main development channel (232) and the sub development channel (235) branch off, and downstream means the part adjacent to the first cover inspection hole (236).
  • variable flow path section (300) may be formed so that at least a portion of the sub-development channel (235) has a smaller flow cross-sectional area.
  • the variable flow path section (300) may be formed so that the flow cross-sectional area is the same from upstream to downstream.
  • the variable flow path section (300) presented in this embodiment may be formed so that the width of the variable flow path section (300) is narrower and longer.
  • an in vitro diagnostic strip includes a strip body (10), a main development channel (212, 232) formed on the strip body (10) and through which a sample introduced into the strip body (10) is developed, and a plurality of sub-development channels (216, 235) branching out and extending from one side of the main development channel (212, 232) and through which the sample is developed, and a blocking flow path (400) for changing the flow direction of the sample is formed in the sub-development channel (216, 235), thereby blocking the sample from flowing in the opposite direction in the test hole (218, 236).
  • a blocking flow path part (400) for changing the flow direction of a sample may be formed in the sub-development channel (235).
  • the blocking flow path part (400) is illustrated as being formed in the sub-development channel (235) formed in the first cover film (230), but a blocking flow path part (400) may be formed correspondingly in the sub-development channel (216) of the channel part (200).
  • the inspection holes (218, 236) may include an inspection hole (218) formed in the channel part (200) and a first cover inspection hole (236) formed in the first cover film (230).
  • a blocking flow path (400) is formed in the sub-expansion channel (235) to prevent this.
  • the blocking flow path (400) can be formed so that it can basically change to the flow direction of the sample in order to block the backflowing sample.
  • the blocking flow path (400) may be formed to divert at least a portion of the flow direction (linear direction) of the sub-development channel (235). In one embodiment, the blocking flow path (400) may be arranged perpendicularly at 90 degrees to the flow direction of the sub-development channel (235). When the blocking flow path (400) is formed to divert in this way to the flow direction of the sample, it is possible to restrict the sample from flowing backwards toward the sub-development channel (235) when flowing backwards.
  • a connecting passage part (410) may be formed at each of the upstream and downstream ends of the blocking passage part (400).
  • the connecting passage part (410) is a part formed to connect the blocking passage part (400) to the sub-deployment channel (235).
  • the connecting passage part (410) may be arranged at each of the front and rear ends of the blocking passage part (400).
  • the connecting flow path (410) can be formed to have the same flow direction as the flow direction of the sub-development channel (235).
  • a sample introduced through the sub-development channel (235) can pass through the connecting flow path (410) -> blocking flow path (400) -> connecting flow path (410), and even if the sample flows in reverse, the flow from the connecting flow path (410) to the blocking flow path (400) can be restricted.
  • the blocking flow path (400) may be positioned at the downstream end of the sub-development channel (235). That is, the blocking flow path (400) may be positioned adjacent to the first cover inspection hole (236) positioned at the downstream end of the sub-development channel (235) to effectively block the flow of a sample flowing backwards in the first cover inspection hole (236).
  • the connecting flow path part (410) may be formed to have a narrower width than the sub-deployment channel (235). In one embodiment, the connecting flow path part (410) may have different positions in the width direction at a point where it is connected to the blocking flow path part (400). Referring to FIG. 6, the connecting flow path part (410) positioned on the left is positioned in the center in the width direction, and the connecting flow path part (410) positioned on the right is positioned downward in the width direction. Referring to FIG. 7, the connecting flow path part (410) positioned on the left is positioned upward in the width direction, and the connecting flow path part (410) positioned on the right is positioned downward in the width direction. In addition, referring to FIG. 8, the connecting flow path part (410) positioned on the left is positioned downward in the width direction, and the connecting flow path part (410) positioned on the right is positioned upward in the width direction.
  • FIG. 9 is an enlarged plan view showing an embodiment of the blocking flow path part shown in FIG. 6 combined with an embodiment of the variable flow path part shown in FIG. 3
  • FIG. 10 is an enlarged plan view showing an embodiment of the blocking flow path part shown in FIG. 6 combined with an embodiment of the variable flow path part shown in FIG. 4
  • FIG. 11 is an enlarged plan view showing an embodiment of the blocking flow path part shown in FIG. 6 combined with an embodiment of the variable flow path part shown in FIG. 5.
  • the present embodiments combine the configuration of the variable flow path (300) illustrated in FIGS. 3 to 5 and the configuration of the blocking flow path (400) illustrated in FIGS. 6 to 8.
  • a variable flow path section (300) may be arranged in the sub-deployment channel (235), and a blocking flow path section (400) may be arranged downstream of the variable flow path section (300).
  • the blocking flow path section (400) may be arranged at the downstream end of the sub-deployment channel (235).
  • the variable flow path section (300) may be arranged immediately in front of the blocking flow path section (400), or may be arranged at a point upstream from the blocking flow path section (400).
  • FIGS. 9 to 11 only an embodiment is shown in which the configuration of the blocking flow path part (400) shown in FIG. 6 and the configuration of the variable flow path part (300) shown in FIGS. 3 to 5 are combined in the sub-deployment channel (235), but this is not limited thereto, and an embodiment in which the configuration of the blocking flow path part (400) shown in FIGS. 7 or 8 and the configuration of the variable flow path part (300) shown in FIGS. 3 to 5 are each combined is also possible.
  • Second cover vent hole 240 Second cover film
  • Second injection hole 246 Second cover inspection hole

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

Une bandelette de diagnostic in vitro selon un mode de réalisation de la présente invention comprend : un corps principal de bandelette auquel un échantillon est introduit ; un canal de déploiement principal formé dans le corps principal de bandelette, pour propager l'échantillon introduit dans le corps principal de bandelette ; et une pluralité de canaux de sous-déploiement se ramifiant et s'étendant à partir d'un côté du canal de déploiement principal, pour propager l'échantillon, les canaux de sous-déploiement pouvant comprendre une partie de canal d'écoulement variable, au moins une partie de la surface de section transversale d'écoulement étant effilée.
PCT/KR2024/012683 2023-08-25 2024-08-26 Bandelette de diagnostic in vitro Pending WO2025048427A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2023-0111869 2023-08-25
KR20230111869 2023-08-25
KR10-2024-0113293 2024-08-23
KR1020240113293A KR20250030935A (ko) 2023-08-25 2024-08-23 체외 진단 스트립

Publications (1)

Publication Number Publication Date
WO2025048427A1 true WO2025048427A1 (fr) 2025-03-06

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Application Number Title Priority Date Filing Date
PCT/KR2024/012683 Pending WO2025048427A1 (fr) 2023-08-25 2024-08-26 Bandelette de diagnostic in vitro

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WO (1) WO2025048427A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030138829A1 (en) * 2001-11-30 2003-07-24 Fluidigm Corp. Microfluidic device and methods of using same
JP2009178146A (ja) * 2008-02-01 2009-08-13 Seiko Epson Corp 生体試料反応用チップおよび生体試料反応方法
JP2009284769A (ja) * 2008-05-27 2009-12-10 Sony Corp マイクロ基板
KR20140010506A (ko) * 2012-07-12 2014-01-27 삼성전자주식회사 유체 분석 카트리지
JP2014199206A (ja) * 2013-03-29 2014-10-23 ソニー株式会社 マイクロチップ及びマイクロチップの製造方法
KR20230109850A (ko) * 2022-01-14 2023-07-21 동서대학교 산학협력단 신속, 다중 면역검사칩

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030138829A1 (en) * 2001-11-30 2003-07-24 Fluidigm Corp. Microfluidic device and methods of using same
JP2009178146A (ja) * 2008-02-01 2009-08-13 Seiko Epson Corp 生体試料反応用チップおよび生体試料反応方法
JP2009284769A (ja) * 2008-05-27 2009-12-10 Sony Corp マイクロ基板
KR20140010506A (ko) * 2012-07-12 2014-01-27 삼성전자주식회사 유체 분석 카트리지
JP2014199206A (ja) * 2013-03-29 2014-10-23 ソニー株式会社 マイクロチップ及びマイクロチップの製造方法
KR20230109850A (ko) * 2022-01-14 2023-07-21 동서대학교 산학협력단 신속, 다중 면역검사칩

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