WO2024237275A1 - Agricultural and horticultural insect pest control agent and insect pest control method using same - Google Patents

Abstract

Provided is an agricultural and horticultural insect pest control agent exhibiting excellent controlling effect on agricultural insect pests including sap-sucking pests, e.g., Hemiptera pests typified by whiteflies and aphids and Thrips pests, and Lepidoptera pests. Also provided is an insect pest control method for useful plants using the agricultural and horticultural insect pest control agent. The agricultural and horticultural insect pest control agent contains, as an active ingredient, a compound having plant disease resistance-inducing activity, such as probenazole, isotianil, dichlobentiazox, tiadinil or acibenzolar-S-methyl. The insect pest control method is for controlling insect pests of useful plants, particularly for controlling agricultural insect pests such as sap-sucking pests and Lepidoptera pests, using the agricultural and horticultural insect pest control agent.

Description

Agricultural and horticultural pest control agent and method for controlling pests using the same

The present invention relates to an agricultural and horticultural pest control agent and a pest control method that contain, as an active ingredient, a compound that has plant disease resistance induction activity.

Conventionally, plant disease resistance inducers (plant activators) activate the defense response function of plants and cause them to develop disease resistance when applied to plants. They are used as agricultural and horticultural disease control agents due to their characteristics such as being unlikely to cause drug resistance, being highly safe, and having a small environmental impact. For example, probenazole (trade name: Oryzemate (registered trademark), etc.), isotianil (trade name: Routine (registered trademark), etc.), diclobentiazox (trade name: Boone (registered trademark)), etc. are commercially available. These plant disease resistance inducers are known to be effective in controlling plant diseases such as rice blast and bacterial leaf blight, and Chinese cabbage soft rot (Patent Documents 1 to 3), but are not known to have a control effect against agricultural pests.

On the other hand, whitefly pests such as the tobacco whitefly and the greenhouse whitefly not only cause sooty mildew on agricultural crops, but also transmit the tomato yellow leaf curl virus and the cucurbit chlorotic yellowing virus, reducing the yield and quality of agricultural crops, making control of these pests essential in the production of horticultural crops such as tomatoes, eggplants, and peppers, as well as cucurbits such as cucumbers.

In addition, thrips pests such as western flower thrips, southern melon thrips, and onion thrips transmit viral diseases and cause serious damage to agricultural production, while the development of drug resistance has been confirmed, making them difficult-to-control pests and a global problem.

Other pests, such as aphid pests like the green peach aphid and the cotton aphid, and lepidopteran pests like the diamondback moth, cutworm moth, cotton bollworm, and rice leafroller, also cause great damage to the yield and quality of agricultural crops, making the control of agricultural pests essential for crop production. Furthermore, as mentioned above, sap-sucking pests like Hemiptera pests like whiteflies and aphids, and thrips pests, are known to transmit plant pathogenic viruses, and as of now there is no treatment for plant pathogenic viruses, it is essential to suppress damage to crops caused by these sap-sucking pests in order to prevent the spread of viral diseases.

　Methods of controlling agricultural pests such as those mentioned above include physical control using insect screens, and biological control using natural enemies such as parasitic wasps such as Aphelenchus vaporariorhiza, Aphelenchus nigricans, and Aphididae colemani, and predatory mites such as Phytoseiulus swirskii, but chemical control using synthetic chemical insecticides is the mainstream. However, with chemical control, it has been reported that many pest species have developed resistance to existing insecticides, and there are also cases where effective control is not possible for various reasons, such as the impact on beneficial natural enemies and organisms other than the target pest, and therefore there is still a need to develop pest control agents that are sufficiently effective at low doses.

Patent Publication No. 45-012157 WO1999/024413A2 WO2007/129454A1

The present invention was made with the aim of providing an agricultural and horticultural pest control agent that has excellent control effects against agricultural pests, such as Hemiptera pests, such as whiteflies and aphids, sap-sucking pests, such as Thripida pests, and Lepidoptera pests.

The inventors conducted extensive research to solve the above problems and discovered that compounds with plant disease resistance induction activity, such as isonianil, diclobentazox, and probenazole, exhibit excellent control activity against agricultural pests, leading to the completion of the present invention.

That is, the present invention provides the following.
[1] An agricultural and horticultural pest control agent comprising, as an active ingredient, a compound having plant disease resistance inducing activity.
[2] The agent according to [1], wherein the compound having plant disease resistance induction activity is one or more compounds selected from the group consisting of probenazole, isotianil, diclobentazox, tiadinil and acibenzolar-S-methyl.
[3] The agent described in [1] or [2] above, which targets sap-sucking pests.
[4] The agent according to [3], wherein the sap-sucking pest is a Hemiptera pest or a Thripida pest.
[5] The agent according to [4], wherein the Hemiptera pest is a whitefly pest or an aphid pest.
[6] The agent according to [1] or [2] above, which targets lepidopteran pests.
[7] A method for controlling pests, which comprises applying a compound having plant disease resistance inducing activity to a useful plant, a place where a useful plant is to be grown, or a place where a useful plant is growing.
[8] The pest control method according to [7], wherein the compound having plant disease resistance induction activity is one or more compounds selected from the group consisting of probenazole, isotianil, diclobentazox, tiadinil and acibenzolar-S-methyl.
[9] The pest control method according to the above [7] or [8], wherein the application amount of the compound having plant disease resistance inducing activity to a useful plant is 0.1 to 1000 mg per plant body.
[10] The pest control method according to any one of [7] to [9], wherein the target of control is a sap-sucking pest.
[11] The pest control method according to [10], wherein the sap-sucking pests are Hemiptera or Thripidae pests.
[12] The pest control method according to [11], wherein the Hemiptera pest is a whitefly pest or an aphid pest.
[13] The pest control method according to any one of [7] to [9], wherein the target of control is a Lepidoptera pest.

The agricultural and horticultural pest control agent of the present invention is highly effective in controlling agricultural pests such as Hemiptera pests such as whiteflies and aphids, sap-sucking pests such as Thripida pests, and Lepidoptera pests.

The present invention will be described in detail below. The agricultural and horticultural pest control agent of the present invention contains a compound having plant disease resistance induction activity as an active ingredient. Examples of compounds having plant disease resistance induction activity include, but are not limited to, acibenzolar-S-methyl, probenazole, tiadinil, isotianil, dichlobentiazox, and fosetyl. Any compound having plant disease resistance induction activity may be used, but is preferably selected from the group consisting of probenazole, isotianil, and dichlobentiazox, more preferably selected from the group consisting of isotianil and dichlobentiazox, and more preferably dichlobentiazox. The agricultural and horticultural pest control agent of the present invention may contain at least one compound having plant disease resistance induction activity, and may contain a combination of two or more compounds having plant disease resistance induction activity.

The agricultural and horticultural pest control agent of the present invention can contain, in addition to the active ingredient, additives that are commonly used in pesticide formulations, if necessary. Examples of additives include carriers such as solid or liquid carriers, surfactants, binders and tackifiers, thickeners, colorants, spreading agents, adhesives, antifreeze agents, anticaking agents, disintegrants, antidecomposition agents, antidrift agents, and antifoaming agents. If necessary, preservatives, plant pieces, and the like may also be used as additives. These additives may be used alone or in combination of two or more.

　Explain the added ingredients listed above.

Examples of solid carriers include natural minerals such as quartz, clay, silica sand, kaolinite, pyrophyllite, sericite, talc, bentonite, acid clay, attapulgite, zeolite, and diatomaceous earth; inorganic salts such as calcium carbonate, ammonium sulfate, sodium sulfate, and potassium chloride; organic solid carriers such as synthetic silicic acid, synthetic silicates, starch, cellulose, and plant powder; plastic carriers such as polyethylene, polypropylene, and polyvinylidene chloride; urea, inorganic hollow bodies, plastic hollow bodies, and fumed silica (white carbon). These may be used alone or in combination of two or more.

Liquid carriers include, for example, monohydric alcohols such as methanol, ethanol, propanol, isopropanol, and butanol; alcohols broadly classified as polyhydric alcohols such as ethylene glycol, diethylene glycol, propylene glycol, hexylene glycol, polyethylene glycol, polypropylene glycol, and glycerin; polyhydric alcohol derivatives such as propylene glycol ethers; ketones such as acetone, methyl ethyl ketone, methyl isobutyl ketone, diisobutyl ketone, and cyclohexanone; ethers such as ethyl ether, dioxane, ethylene glycol monoethyl ether, dipropyl ether, and tetrahydrofuran; and normal paraffin. Examples of the oils include aliphatic hydrocarbons such as naphthene, isoparaffin, kerosene, and mineral oil; aromatic hydrocarbons such as benzene, toluene, xylene, solvent naphtha, and alkylnaphthalene; halogenated hydrocarbons such as dichloroethane, chloroform, and carbon tetrachloride; esters such as ethyl acetate, diisopropyl phthalate, dibutyl phthalate, dioctyl phthalate, and dimethyl adipate; lactones such as γ-butyrolactone; amides such as dimethylformamide, diethylformamide, dimethylacetamide, and N-alkylpyrrolidinone; nitriles such as acetonitrile; sulfur compounds such as dimethyl sulfoxide; vegetable oils such as soybean oil, rapeseed oil, cottonseed oil, and castor oil; and water. These may be used alone or in combination of two or more.

Surfactants include, for example, sorbitan fatty acid esters, polyoxyethylene sorbitan fatty acid esters, sucrose fatty acid esters, polyoxyethylene fatty acid esters, polyoxyethylene resin acid esters, polyoxyethylene fatty acid diesters, polyoxyethylene alkyl ethers, polyoxyethylene alkyl aryl ethers such as polyoxyethylene alkyl phenyl ethers, polyoxyethylene dialkyl phenyl ethers, polyoxyethylene alkyl phenyl ether formalin condensates, polyoxyethylene polyoxypropylene block polymers, alkyl polyoxyethylene polypropylene block polymer ethers, polyoxyethylene alkyl amines, polyoxyethylene fatty acid amides, polyoxyethylene fatty acid bisphenyl ethers, polyalkylene benzyl phenyl ethers, polyoxyalkylene styryl phenyl ethers, acetylenic diols, polyoxyalkylene-added acetylenic diols, silicone surfactants such as polyoxyethylene ether-type silicones and ester-type silicones, fluorine-based surfactants, and non-ionic surfactants such as hydrogenated castor oil, polyoxyethylene castor oil, and polyoxyethylene hydrogenated castor oil. Examples of the surfactant include alkyl sulfates such as sodium salts of lauryl alcohol sulfate, polyoxyethylene alkyl ether sulfates, polyoxyethylene alkyl phenyl ether sulfates, polyoxyethylene styryl phenyl ether sulfates, alkyl benzene sulfonates, alkyl aryl sulfonates, lignin sulfonates, alkyl sulfosuccinates, naphthalene sulfonates, alkyl naphthalene sulfonates, salts of formalin condensates of naphthalene sulfonic acid, salts of formalin condensates of alkyl naphthalene sulfonic acid, fatty acid salts, polycarboxylates, N-methyl-fatty acid sarcosinates, resin salts, polyoxyethylene alkyl ether phosphates, and anionic surfactants such as polyoxyethylene alkyl phenyl ether phosphates; alkyl amine salts such as laurylamine hydrochloride, stearylamine hydrochloride, oleylamine hydrochloride, stearylamine acetate, stearylaminopropylamine acetate, alkyl trimethylammonium chloride, and alkyl dimethyl benzalkonium chloride; cationic surfactants such as dialkyl dimethyl ammonium polynaphthylmethanesulfonate; and amphoteric surfactants such as amino acid type or betaine type. These surfactants may be used alone or in combination of two or more.

Binders and tackifiers include, for example, cellulose and its derivatives, such as carboxymethylcellulose and its salts, dextrin, water-soluble starch, alpha-starch, modified starch, sucrose, polyvinylpyrrolidone, gum arabic, xanthan gum, guar gum, and other polysaccharides, cephalin, lecithin, and other phospholipids, polyvinyl alcohol, polyvinyl alkyl ether, polyvinyl acetate, sodium polyacrylate, polyethylene glycol with an average molecular weight of 6,000 to 5,000,000, polyaminocarboxylic acid chelate compounds, copolymers of maleic acid and styrene acid, acrylic acid copolymers, half esters of polyhydric alcohols with parimate dicarboxylic anhydride, water-soluble salts of polystyrene sulfonic acid, polyamide resins, alkylphenol-formaldehyde condensates, polymers such as synthetic resin emulsions, paraffin, terpene, wax, and natural phospholipids (e.g., cephalic acid, lecithin, etc.). These binders and tackifiers may be used alone or in combination of two or more.

Thickeners include, for example, xanthan gum, guar gum, diutan gum, carboxymethylcellulose, polyvinylpyrrolidone, carboxyvinyl polymers, acrylic polymers, starch derivatives, water-soluble polymers such as polysaccharides, high-purity bentonite, and inorganic fine powders such as fumed silica (white carbon). These thickeners may be used alone or in combination of two or more.

Examples of colorants include inorganic pigments such as iron oxide, titanium oxide, and Prussian blue, and organic dyes such as alizarin dyes, azo dyes, and metal phthalocyanine dyes. These colorants may be used alone or in combination of two or more.

Examples of spreading agents include silicone surfactants, cellulose powder, dextrin, modified starch, polyaminocarboxylic acid chelate compounds, cross-linked polyvinylpyrrolidone, copolymers of maleic acid and styrenes, (meth)acrylic acid copolymers, half esters of polymers of polyhydric alcohols and dicarboxylic acid anhydrides, water-soluble salts of polystyrene sulfonic acid, etc. These spreading agents may be used alone or in combination of two or more.

Examples of spreading agents include various surfactants such as sodium dialkyl sulfosuccinate, polyoxyethylene alkyl ethers, polyoxyethylene alkyl phenyl ethers, and polyoxyethylene fatty acid esters, as well as paraffin, terpene, polyamide resins, polyacrylates, polyoxyethylene, wax, polyvinyl alkyl ethers, alkylphenol-formaldehyde condensates, and synthetic resin emulsions. These spreading agents may be used alone or in combination of two or more.

Examples of antifreeze agents include polyhydric alcohols such as ethylene glycol, diethylene glycol, propylene glycol, and glycerin. These antifreeze agents may be used alone or in combination of two or more.

Examples of anti-caking agents include polysaccharides such as starch, alginic acid, mannose, and galactose, polyvinylpyrrolidone, white carbon, ester gum, and petroleum resins. These anti-caking agents may be used alone or in combination of two or more.

Disintegrants include, for example, sodium tripolyphosphate, sodium hexametaphosphate, metal stearates, cellulose powder, dextrin, copolymers of methacrylic acid esters, polyvinylpyrrolidone, polyaminocarboxylic acid chelate compounds, sulfonated styrene-isobutylene-maleic anhydride copolymers, starch-polyacrylonitrile graft copolymers, etc. These disintegrants may be used alone or in combination of two or more kinds.

Examples of decomposition inhibitors include desiccants such as zeolite, quicklime, and magnesium oxide, antioxidants such as phenols, amines, sulfurs, and phosphoric acids, and ultraviolet absorbers such as salicylic acid and benzophenones. These decomposition inhibitors may be used alone or in combination of two or more.

Drift prevention agents include, for example, methyl cellulose, polyvinyl alcohol, water-soluble polymers such as starch, polyisobutylene, polyethylene glycol, polypropylene glycol, glycerin, petroleum resins, polystyrene, polyvinyl acetate, epoxy resins, etc. These drift prevention agents may be used alone or in combination of two or more.

Examples of defoaming agents include dimethylpolysiloxane, modified silicone, polyether, fatty acid ester, fatty acid salt, etc. These defoaming agents may be used alone or in combination of two or more.

Examples of preservatives include sodium benzoate, sodium parahydroxybenzoate, potassium sorbate, 1,2-benzthiazolin-3-one, formalin, etc. These preservatives may be used alone or in combination of two or more.

Examples of plant pieces include sawdust, coconut shells, corn cobs, tobacco stalks, etc. These plant pieces may be used alone or in combination of two or more types.

Furthermore, if necessary, activity enhancers such as metabolic decomposition inhibitors, such as piperonyl butoxide, can also be used.

The agricultural and horticultural pest control agent of the present invention can also contain one or more pesticide active ingredients in addition to the active ingredient, a compound having plant disease resistance inducing activity.

Examples of pesticide active ingredients that can be mixed include herbicidal active ingredients, insecticidal active ingredients, acaricidal active ingredients, nematicidal active ingredients, synergistic active ingredients, fungicidal active ingredients, and plant growth regulating active ingredients, but the present invention is not limited to these pesticide active ingredients.

[Herbicidal active ingredient]
ioxynil [including lithium salt, sodium salt, salt with octanoic acid, etc.], aclonifen, acrolein, azafenidine, acifluorfen (including salt with sodium, etc.), azimsulfuron, asulam, acetochlor, atrazine ), Anisiflupurin, Anilofos, Amicarbazone, Amidosulfuron, Amitrol, Aminocyclopyrachlor, Aminopyralid, Amiprofos-methyl, Ametryn, Arausia Mosaic Virus, Alachlor, Alternaria destolens destruens, alloxydim, ancymidol, icafolin-methyl [including salts with sodium etc.], isouron, isoxachlortole, isoxaflutole, isoxaben, isodecyl alcohol ethoxylate, isoproturon, iptriazopyride riazopyrid, ipfencarbazone, imazaquin, imazapic (including salts with amines, etc.), imazapyr (including salts with isopropylamine, etc.), imazamethabenz, imazamethabenz-methyl, imazamox, imazethapyr, imazosulfuron, indaziflam iflam), indanofan, indolauxipyr-cyanomethyl, eglinazine-ethyl, esprocarb, ethametsulfuron-methyl, ethalfluralin, ethidimuron, ethoxysulfuron, ethoxyfen, ethoxyfen- Ethoxyphen-ethyl, etofumesate, etobenzanide, epirifenacil, endothal disodium salt, oxadiazon, oxadiargyl, oxaziclomefone, oxasulfuron, oxyfluorfen, oryzalin, ovuda Pepper Virus, orthosulfamuron, orbencarb, oleic acid, cafenstrole, caprylic acid, capric acid acid), carfentrazone-ethyl, carbutilate, carbetamide, quizalofop, quizalofop-ethyl, quizalofop-P-ethyl, quizalofop-P-tefuryl, Xanthomonas campestris, quinoclamin, quinclorac, quinmerac, citric acid acid), cumyluron, clacyfos, glyphosate (including salts such as sodium, potassium, amine, propylamine, isopropylamine, ammonium, isopropylammonium, guanidine, monoethanolamine, choline, BAPMA (N,N-bis-(3-aminopropyl)methylamine), dimethylamine, or trimesium), glufosinate (amine or sodium salts), um salts), glufosinate-P, glufosinate-P-sodium salt, clethodim, clodinafop, clodinafop-propargyl, clopyralid (including monoethanolamine salts), clomazone, clomethoxyphen hoxyfen, clomeprop, cloransulam-methyl, chloramben, chloridazon, chlorimuron, chlorimuron-ethyl, chlorsulfuron, chlorthal-dimethyl, chlorthiamid rthiamid), chlorphthalim, chlorflurenol-methyl, chlorpropham, chlorbromuron, chloroxuron, chlorotoluron, ketospiradox (including salts such as sodium, calcium or ammonia), colletotrichum Colletotrichum orbiculare, Colletotrichum gloeosporioides, Colletotrichum truncatum, Chondrostercum purpurea purpureum), saflufenacil, sarmentine, cyanazine, cyanamide, diuron, diethyl-ethyl, dioxopyritrione, dicamba (including amines, diethylamine, isopropylamine, diglycolamine, dimethylammonium, diolamine, isopropylammonium, olamine, potassium, trolamine, BAPMA (N,N-bis-(3-aminopropyl)methylamine), choline, salts such as sodium or lithium, or esters such as methyl esters), cycloate, cyclooxydim ), diclosulam, cyclosulfamuron, cyclopyranil, cyclopyrimorate, dichlobenil, diclofop, diclofop-P-methyl, diclofop-methyl, dichlorprop, dichlorprop-P (including salts of dimethylammonium, potassium, sodium, choline, etc., or esters of butotyl ester, 2-ethylhexyl ester, isoctyl ester, methyl ester, etc.), diquat, diquat dibromide dibromide, dithiopyr, siduron, dinitramine, cinidon-ethyl, cinosulfuron, dinoseb (including salts of acetate, ammonium, diolamine, sodium, trolamine, etc.), dinoterb, cyhalofop, cyhalofop-butyl, cypyrafluone, diphenamide ), difenzoquat, diflufenican, diflufenzopyr, simazine, dimesulfazet, dimethachlor, dimethametryn, dimethenamid, dimethenamid-P, simetryn, dimepiperate, dimefuron, pseudomonas Pseudomonas fluorescens, cinmethylin, swep, sulcotrione, sulfentrazone, sulfosate, sulfosulfuron, sulfometuron-methyl, sethoxydim, celerotinia minor, terbacil, daimuron, thaxtomin A, tobacco mild green mosaic tobamovirus Mosaic Tobamovirus, Tobacco Rattle Virus, dalapon, thiazopyr, thiafenacil, thiencarbazone (including sodium salt, methyl ester, etc.),
Thiocarbazil, thiobencarb, thidiazimine, thidiazuron, thifensulfuron, thifensulfuron-methyl, desmedipham, desmetryne, tetflupyrolimet, thenylchlor, tebutam, Tebuthiuron, tepraloxydim, tefuryltrione, terbuthylazine, terbutryn, terbumeton, tembotrione, topramezone, tralkoxydim, triaziflam, triasulfuron, triafamone one), tri-allate, trietazine, triclopyr, triclopyr-butotyl, triclopyr-triethylammonium, tritosulfuron, tripyrasulfone, trifludimoxazin, triflusulfuron-methyl thyl), trifluralin, trifloxysulfuron (including salts with sodium, etc.), tribenuron-methyl, tolpyralate, naptalam (including salts with sodium, etc.), naproanilide, napropamide, napropamide-M, nicosulfuron, lactic acid acid), neburon, norflurazon, Burkholderia rinogensis, vernolate, paraquat, paraquat dichloride dichloride), haloxifen, haloxifen-benzyl, haloxifen-methyl, haloxyfop, haloxyfop-P, haloxyfop-ethoxyl, haloxyfop-P-methyl, halosafen, halosulfuron-methyl losulfuron-methyl, bixlozone, picloram (including salts with dichloroammonium, trolamine, etc.), picolinafen, bicyclopyrone, bispyribac-sodium, pinoxaden, bipyrazone, bifenox, piperophos, pyrakine pyraquinate, pyraclonil, pyrasulfotole, pyrazoxyfen, pyrazosulfuron-ethyl, pyrazolinate, bilanafos, pyraflufen, pyraflufen-ethyl, pyridafol, pyrithiobac-sodium Salt (pyrithiobac-sodium), pyridate, pyriftalid, pyributicarb, pyriflubenzoxim, pyribenzoxim, pyrimisulfan, pyriminobac-methyl, pyroxasulfone, pyroxsulam, phytopsora Phytophthora palmivora, phenisopham, fenuron, fenoxasulfone, fenoxaprop (including methyl, ethyl, isopropyl esters), fenoxaprop-P (including methyl, ethyl, isopropyl esters), fenquinotrione, fenthiaprop-ethyl, fentrazamide, fenpyrazone, phenmedipham, Phoma chenopdicola, Phoma Phoma herbarum, Phoma macrostoma, butachlor, butafenacil, butamifos, butyrate, Puccinia canaliculata, Puccinia sraspeos thlaspeos), butenachlor, butralin, butroxydim, flazasulfuron, flamprop (including methyl, ethyl, isopropyl esters), flamprop-M (including methyl, ethyl, isopropyl esters), primisulfuron, primisulfuron-methyl primisulfuron-methyl, fluazifop-butyl, fluazifop-P, fluazifop-P-butyl, fluazolate, fluometuron, fluoroglycofen-ethyl, flucarbazone-sodium salt ne-sodium), fluchloraminopyr (including tetrahydrofurfuryl ester), fluchloralin, flusulfinam, flucetosulfuron, fluthiacet-methyl, flupyrsulfuron-methyl (containing sodium, calcium or anhydride) monia and other salts), flufenacet, flufenoximacil, flufenpyr-ethyl, flupropanate (including sodium salt), flupoxame, flumioxazin, flumiclorac-pentyl, flumetsulam am), fluridone, flurtamone, fluroxypyr (including esters such as butomethyl and meptyl, or salts of sodium, calcium, ammonia, etc.), flurochloridone, pretilachlor, procarbazone (including salts with sodium, etc.), broclozone, prodia Prodiamine, prosulfuron, prosulfocarb, propaquizafop, propachlor, propazine, propanil, propyzamide, propisochlor, propyrisulfuron, propham, ropham, profluazol, prohexadione-calcium salt, propoxycarbazone, propoxycarbazone-sodium salt, profoxydim, bromacil, brompyrazone, prometryn , prometon, bromoxynil (including esters of butyric acid, octanoic acid, heptanoic acid, etc.), bromofenoxim, bromobutide, florasulam, florpyroxifen, florpyroxifen-benzyl, hexazinone,
Petoxamid, benazolin (including salts such as dimethylammonium or potassium), benazolin-ethyl, penoxsulam, pepino mosaic virus, heptamaloxyloglucan, beflubutamid, beflubutamid-M, pebulate, pelargonic acid acid, bencarbazone, benquitrione, benzfendizone, bensulide, bensulfuron-methyl, benzobicyclon, benzofenap, bentazone, pentanochlor, pendimethalin, pentoxazone oxazone), benfluralin, benfuresate, fosamine, fomesafen, foramsulfuron, forchlorfenuron, mecoprop (sodium, potassium, isopropylamine, triethanolamine, dimethylamine, diolamine, trolamine, choline salts, or ethadiyl esters, 2-ethylhexyl esters, isocyanate salts, mecoprop-P-potassium, mesosulfuron (including esters such as methyl esters), mesotrione, metazachlor, metazosulfuron, methabenzthiazuron, metamitron, metamifop, metam (sodium methanearsonate disodium (DSMA), methiozolin, methyldymuron, metoxuron, metosulam, metsulfuron-methyl, metobromuron, metobenzuron, metolachlor, metribuzin, mepiquat chloride, chloride), mefenacet, monosulfuron (including methyl, ethyl, isopropyl esters), monolinuron, molinate, iodosulfuron, iodosulfuron-methyl-sodium salt, iofensulfuron, iofensulfuron-sodium salt -sodium), lactofen, lancotrione, linuron, rimisoxafen, rimsulfuron, lenacil, 2,2,2-trichloroacetic acid (TCA) (including salts such as sodium, calcium or ammonia), 2,3,6-trichlorobenzoic acid (2,3,6-TBA), 2,4,5-trichlorophenoxyacetic acid (2,4,5-T), 2,4-dichlorophenoxyacetic acid (2 ,4-D) (including amines, diethylamine, triethanolamine, isopropylamine, dimethylammonium, diolamine, dodecylammonium, heptylammonium, tetradecylammonium, triethylammonium, tris(2-hydroxypropyl)ammonium, trolamine, choline, salts such as sodium or lithium, or esters such as butotyl ester, 2-butoxypropyl ester, 2-ethylhexyl ester, methyl ester, ethyl ester, butyl ester, isobutyl ester, octyl ester, pentyl ester, propyl ester, isoctyl ester, isopropyl ester, meptyl ester, and tefuryl ester), 2-amino-3-chloro-1,4-naphthoquinone (ACN), 2-methyl-4-chlorophenoxyacetic acid (MCPA) (including salts such as sodium, dimethylammonium, and choline, or esters such as 2-ethylhexyl ester, isoctyl ester, and ethyl ester), 2-methyl-4-chlorophenoxybutyric acid (MCPB) (including sodium salt, ethyl ester, etc.) , 4-(2,4-dichlorophenoxy)butyric acid (2,4-DB) (including amines, diethylamine, triethanolamine, isopropylamine, dimethylammonium, choline, salts such as sodium or lithium, or esters such as isoctyl ester), 4,6-dinitro-O-cresol (DNOC) (including amines or salts such as sodium), (5S)-3-(3,5-difluorophenyl)-N-[rel-(3R,5R)-5-(trifluoromethylsulfonylcarbamoyl)tetrahydrofuran-3-yl]-5 -vinyl-4H-isoxazole-5-carboxamide ((5S)-3-(3,5-difluorophenyl)-N-[rel-(3R,5R)-5-(trifluoromethylsulfonylcarbamoyl)tetrahydrofuran-3-yl]-5-vinyl-4H-isoxazole-5-carboxamide) (chemical name, CAS registration number: 2266183-40-6) (WO 2018/228986, WO 2020/114934), N4-(2, N4-(2,6-difluorophenyl)-6-(1-fluoro-1-methylethyl)-1,3,5-triazine-2,4-diamine (chemical name, CAS registration number: 1606999-43-2) (WO 2014/064094, WO 2015/162164), (5S)-3-(3,5-difluorophenyl)-N-[(3R)-5-(methyl (5S)-3-(3,5-difluorophenyl)-N-[(3R)-5-(methylsulfonylcarbamoyl)-2,3-dihydrofuran-3-yl]-5-vinyl-4H-isoxazole-5-carboxamide (chemical name, CAS registration number: 2266190-06-9) (WO 2018/228986, WO 202 0/114934), (5R)-3-(3,5-difluorophenyl)-5-methyl-N-[rel-(3R,5R)-5-(methylsulfonylcarbamoyl)tetrahydrofuran-3-yl]-4H-isoxazole-5-carboxamide mid) (chemical name, CAS registration number: 2266164-36-5) (WO 2018/228986, WO 2020/114934), (5R)-3-(3,5-difluorophenyl)-N-[(3R)-5-(methoxycarbamoyl)-2,3-dihydrofuran-3-yl]-5-methyl-4H-isoxazole-5-carboxamide ((5R)-3-(3,5-difluorophenyl)-N-[(3R)-5-(methoxycarbamoyl)-2,3-dihydrofuran-3-yl]-5-methyl-4H-isoxazole-5-carboxamide n-3-yl]-5-methyl-4H-isoxazole-5-carboxamid) (chemical name, CAS registration number: 2266170-31-2) (WO 2018/228986, WO 2020/114934), 4-hydroxy-1-methyl-3-[4-(trifluoromethyl)-2-pyridyl]imidazolidin-2-one (chemical name, CAS registration number: 2266170-31-2) (WO 2018/228986, WO 2020/114934), Chemical name, CAS registration number: 1708087-22-2) (WO 2015/059262, WO 2018/015476), 6-(1-fluorocyclopentyl)-N4-(2,3,5,6-tetrafluorophenyl)-1,3,5-triazine-2,4-diamine (chemical name, CAS registration number: 1820807-75-7 ) (WO 2015/162164), 6-(1-fluoro-1-methylethyl)-N4-(2,3,5,6-tetrafluorophenyl)-1,3,5-triazine-2,4-diamine (6-(1-fluoro-1-methylethyl)-N4-(2,3,5,6-tetrafluorophenyl)-1,3,5-triazine-2,4-diamine) (chemical name, CAS registration number: 1606999-21-6) (WO 2014/064094, WO 2015/16216 No. 4), (5S)-3-(3-fluoro-5-methylphenyl)-N-[rel-(3R,5R)-5-(methoxycarbamoyl)tetrahydrofuran-3-yl]-5-vinyl-4H-isoxazole-5-carboxamide (chemical name: CA S Registration Number: 2266292-43-5) (WO 2018/228986, WO 2020/114934), 6-(1-methylcyclobutyl)-N4-(2,3,5,6-tetrafluorophenyl)-1,3,5-triazine-2,4-diamine (6-(1-methylcyclobutyl)-N4-(2,3,5,6-tetrafluorophenyl)-1,3,5-triazine-4,4-diamine) (chemical name, CAS Registration Number: 1607001-97-7) (WO WO 2014/064094, WO 2015/162164), AE-F-150944 (code number), IR-6396 (code number), MCPA-thioethyl, SYP-298 (code number), SYP-300 (code number), S-ethyl dipropyl thiocarbamate (EPTC), S-metolachlor, S-9750 (code number), sodium methylarsonate (MSMA), HW-02 (code number), S-523 (code number).

[Insecticidal active ingredient, acaricidal active ingredient, nematicidal active ingredient and synergistic active ingredient]
Acrinathrin, azadirachtin, azamethiphos, acinonapyr, azinphos-ethyl, azinphos-methyl, acequinocyl, acetamiprid, acetoprole, acephate, azocyclotine zocyclotin, abamectin, afidopyropene, afoxolaner, amidoflumet, amitraz, alanycarb, aldicarb, aldoxycarb, allethrin [including d-cis-trans- and d-trans-isomers], isazophos phos), isamidophos, isocarbophos, isoxathion, isocycloseram, isofenphos-methyl, isoprocarb, epsilon-metofluthrin, epsilon-momfluorothrin, ivermectin ivermectin, imicyafos, imidacloprid, imiprothrin, indazapyroxameth, indoxacarb, esfenvalerate, ethiofencarb, ethion, ethiprole, ethylene dibromide dibromide), etoxazole, etofenprox, ethoprophos, etrimfos, emamectin, emamectin benzoate, endosulfan, empenthrin, oxazosulfyl, oxamyl, oxydemeton-methyl, oxydeprofos, omethoate, nuclear polyhedrosis virus virus), cadusafos, kappa-tefluthrin, kappa-bifenthrin, cadethrin, karanjin, cartap, granulosis virus, carbaryl, carbosulfan, carbofuran, gamma-BHC, xylylcarb, quinalphos, kinoprene, chinomethionate, Enteroparalysis virus, virus, coumaphos, cryolite, clothianidin, clofentezine, chromafenozide, chlorantraniliprole, chlorethoxyphos, chlordane, chloropicrin, chlorpyrifos, chlorpyrifos-methyl, chlorfenapyr, chlorfenvinphos, chlorfluazuron uazuron, chlormephos, chloroprallethrin, Entomopoxvirus, Iridovirus, cyazypyr, cyanophos, diafenthiuron, diamidafos, cyantraniliprole, cyetpyrafen, dienochlor, cyenopyrafen, dioxabenzophos, diofenolan, Sigma virus virus), cyclaniliprole, cycloxaprid, dicrotophos, diclofenthion, cyclobutrifluram, cycloprothrin, dichlorvos, dichloromezothiaz otiaz), dicofol, dicyclanil, disulfoton, dinotefuran, dinobuton, cyhalodiamide, cyhalothrin [including gamma- and lambda-forms], cyphenothrin [(1R)-trans- cyfluthrin [including beta-form], diflubenzuron, cyflumetofen, diflovidazin, cyproflanilide, cyhexatin, cypermethrin [alpha-form, beta-form, theta-form, including zeta-isomer], dimpropyridaz, dimethyl-2,2,2-trichloro-1-hydroxyethylphosphonate (DEP), dimethylvinphos, dimethoate, dimefluthrin, jasmone, cis-jasmone, jasmonic acid acid), methyl jasmonate, silafluofen, cyromazine, Steinernema carpocapsae, Steinernema kushidai, Steinernema glacerai glaseri, spidoxamat, spinetoram, spinosad, spirodiclofen, spirotetramat, spiropidione, spirobudifen, spiromesifen, sulcofuron-sodium, sulfuramide, sulfoxaflor lor), sulfotep, diazinon, thiacloprid, thiamethoxam, thioxazafen, thiodicarb, thiocyclam, thiosultap, thionazine, thiofanox, thiometon, thiolantraniliprole, cyclam Pyrazoflor, tetrachlorantraniliprole, tetrachlorvinphos, tetradifon, tetraniliprole, tetramethylfluthrin, tetramethrin, tebupirimfos, tebufenozide, tebufenpyrad ebufenpyrad, tefluthrin, teflubenzuron, demeton-S-methyl, temephos, deltamethrin, terbufos, tralomethrin, transfluthrin, triazamate, triazophos, trichlorfon, trichoderma Asperellum, Trichoderma paecilomyces, Trichoderma harzianum, trifluenfuronate, triflumuron, triflumezopyrim, trimethacarb, tolfenpyrad, naled, nicotine, nicoflurane, nitenpyram, nemadectin, densovirus virus), novaluron, noviflumuron, paecilomyces lilacinus, Burkholderia cepacia, Burkholderia rinogensis, Verticillium lecanii, hydroprene, Pasteuria nishizawae, Pasteuria penetrans, Bacillus amyloliquefaciens amyloliquefaciens, Bacillus firmus,
Insect toxins produced by Bacillus sphaericus, Bacillus subtilis, Bacillus thuringiensis, Bacillus thuringiensis subsp. Aizawai, Bacillus thuringiensis subsp. Israelensis, Bacillus thuringiensis subsp. kurstaki thuringiensis subsp. Kurstaki, Bacillus thuringiensis subsp. Tenebrionis, Bacillus popilliae, Bacillus licheniformis licheniformis, vamidothion, parathion, parathion-methyl, halfenprox, halofenozide, bioallethrin, bioallethrin S-cyclopentenyl S-cyclopentenyl), bioresmethrin, bis-(2-chloro-1-methylethyl) ether (DCIP), bistrifluron, hydramethylnon, bifenazate, bifenthrin, pyflubumid, piperonyl butoxide butoxide, pymetrozine, pyraclofos, pyrafluprole, pyridaphenthion, pyridaben, pyridalyl, pyrifluquinazon, pyriprole, pyriproxyfen, pirimicarb, pyrimidifen, pyriminostrobin, pirimiphos-methyl, pyrethrin hrine), famful, fipronil, fenazaquin, fenamiphos, fenitrothion, fenoxycarb, fenothiocarb, fenothrin [including (1R)-trans-isomer], fenobucarb, fenthion, phenthoate, fenvalerate, fenpyroximate, fenbutanthin oxide oxide), fenpropathrin, phenmezodithiaz, fonofos, sulfuryl fluoride fluoride, butocarboxim, butoxycarboxim, buprofezin, furathiocarb, prallethrin, fluacrypyrim, fluazaindolizine, fluazuron, fluensulfone, fluopyram, sodium fluoroacetate fluoroacetate), fluxametamide, fluchlordiniliprole, flucycloxuron, flucythrinate, flusulfamide, fluthrin, fluvalinate [including tau-form], flupyradifurone, flupyrazofos, flupirimin, flupyroxystrobin, flufiprole, flufenerim, flufenoxystrobin trobin, flufenoxuron, fluhexafon, flubendiamide, flupentiofenox, flumethrin, fluralaner, flurimfen, prothiofos othiofos, protrifenbut, flonicamid, propaphos, propargite, prohydrojasmon, profenofos, broflanilide, broflusurinate ofluthrinate), profluthrin, propetamphos, propoxur, flometoquin, bromopropylate, hexathiazox, hexaflumuron, pekiromyces Paecilomyces tenuipes, Paecilomyces fumosoroseus, Paecilomyces lilacinus, heptafluthrin, heptenophos, permethrin, benclothiaz, benzpyrimoxan, bensultap, benzoximate, bendiocarb, benfuracarb, pochonia Chlamydospori, Beauveria tenella, Beauveria bassiana, Beauveria brongniartii, phoxim, phosalone, fosthiazate, fosthietan, phosphamidon, phosmet, polynactins, formetanate, phorate, machine oil oil), malathion, milbemectin, mecarbam, mesulfenphos, methomyl, metaldehyde, metaflumizone, methamidophos, metham, methiocarb, methidathion, methyl isothiocyanate, methyl bromide bromide), methoxychlor, methoxyfenozide, methothrin, metofluthrin, methoprene, metolcarb, mevinphos, meperfluthrin, Monacrosporium phymatophagum, monocrotophos, momfluorothrin, litlure-A, litlure-B, aluminum phosphide phosphine, zinc phosphide, hydrogen phosphide, lufenuron, rescale, resmethrin, ledprona, lepimectin, rotenone, cytoplasmic polyhedrosis virus, fenbutatin oxide, calcium nitrogen cyanide), organotin compounds, nicotine sulfate, (Z)-10-tetradecenyl acetate, (E,Z)-4,10-tetradecadienyl acetate, (Z)-11-tetradecenyl acetate, (Z)-11-hexadecenal, (Z)-11-hexadecenyl acetate acetate, (Z)-9,12-tetradecadienyl acetate, (Z)-9-tetradecen-1-ol, (Z,E)-9,11-tetradecadienyl acetate, (Z,E)-9,12-tetradecadienyl acetate, (Z)-8-dodecenyl acetate, 1,1,1-trichloro-2,2-bis(4-chlorophenyl)ethane (DD T), 1,3-dichloropropene, 2,4-dichloro-5-{2-[4-(trifluoromethyl)phenyl]ethoxy}phenyl-2,2,2-trifluoroethyl-sulfoxide (chemical name, CAS registration number: 1472052-11-1), 2,4-dimethyl-5-[6-(trifluoromethylthio)hexyloxy]phenyl-2,2,2-trifluoroethyl-sulfoxide (chemical name, CAS registration number: 1472050-34-2), 2-{2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenoxy}-5-(trifluoromethyl)pyridine (chemical name, CAS registration number: 1448758-62-0),
3-Chloro-2-{2-fluoro-4-methyl-5-[(2,2,2-trifluoroethyl)sulfinyl]phenoxy}-5-(trifluoromethyl)pyridine (chemical name, CAS registration number: 1448761-28-1), 4,6-dinitro-o-cresol (DNOC), 4-fluoro-2-methyl-5-(5,5-dimethylhexyloxy)phenyl 2,2,2-trifluoroethyl Sulfoxide (chemical name, CAS registration number: 1472047-71-4), Bt proteins (Cry1Ab, Cry1Ac, Cry1Fa, Cry2Ab, mCry3A, Cry3Ab, Cry3Bb, Cry34/35Ab1), methyleugenol, 4-(p-acetoxyphenyl)-2-butanone, 14-methyl-1-octadecene, CL900167 (code number), O,O-diethyl-O-[ 4-(Dimethylsulfamoyl)phenyl]-phosphorothioate (DSP), O-ethyl-O-4-(nitrophenyl)phenylphosphonothioate (EPN), NA-85 (code number), RU15525 (code number), 3,5-xylylmethylcarbamate (XMC), Z-13-icosen-10-one, ZXI8901 (code number), F4260 (code number), NI-30 (code number).

[Bactericidal active ingredient]
Agrobacterium radiobacter, azaconazole, azoxystrobin, anilazine, amisulbrom, aminopyrifen, ametoctradine, aldimorph, isopyrazam, isofetamide, isoflutamide, isoflutamide, isoprothiolane, ipconazole, ipflufenoquine, ipflufenoquin, ipfentrifluconazole, iprodione, iprovalicarb, iprobenfos, imazalil, iminoctadine-trialbesilate, iminoctadine-triacetate, imibenconazole, inpyrfluxam, imprimatin A A), imprimatin B, edifenphos, etaconazole, ethaboxam, ethirimol, ethoxyquin, etridiazole, enestroburin, enoxastrobin, epoxyconazole, organic oil oils), oxadixyl, oxazinylazole, oxathiapiproline, oxycarboxin, oxyquinoline copper, oxytetracycline, oxpoconazole fumarate, oxolinic acid, copper octanoate dioctanoate, octhilinone, ofurace, orysastrobin, orthophenylphenol, kasugamycin, captafol, carpropamid, carbendazim, carboxin, carbone, Candida oleophila, Candida cytoana saitoana), quinoxyfen, quinofumelin, chinomethionate, captan, quinconazole, quintozene, guazatine, cufuraneb, coumethoxystrobin, coumethoxystrobin, Gliocladium catenulatum, Cryptococcus albidus albidus, kresoxim-methyl, clozylacon, Clonostachys rosea, chlorzolinate, chloroinconazide, chlorothalonil, chloroneb, Chaetomium cupreum, Coniothyrium minitans minitans), cyazofamid, diethofencarb, diclocymet, dichlofluanid, diclomedine, dicloran, dichlorophen, dithianon, diniconazole, diniconazole-M, zineb, zino Dinocap, dipimethitrone, diphenylamine, difenoconazole, cyflufenamid, diflumetrim, cyproconazole, cyprodinil, simeconazole, dimethylimol, dimethyl disulfide disulfide), dimethomorph, cymoxanil, dimoxystrobin, Pseudozyma flocculosa, Pseudomonas aureofaciens, Pseudomonas chlororaphis, Pseudomonas syringae, Pseudomonas fluorescens, Pseudomonas rhodesiae HAI-0804 rhodesiae HAI-0804), ziram, silthiofam, Zucchini yellow mosaic virus attenuated strain, streptomycin, Streptomyces griseoviridis, Streptomyces rhizicus lydicus, spiroxamine, sedaxane, seboctylamine, zoxamide, solatenol, dazomet, Talaromyces flavus flavus, thiabendazole, thiuram, thiophanate, thiophanate-methyl, thifluzamide, tecnazene, tecloftalam, tetraconazole, debacarb, tebuconazole Tebuconazole, tebufloquin, terbinafine, dodine, dodemorph, triadimenol, triadimefon, triazoxide, trichlamide, triclopyricarb, trichoderma Trichoderma asperellum, Trichoderma atroviride, Trichoderma gamsii, Trichoderma stromaticum, Trichoderma paecilomyces, Trichoderma harzianum, Trichoderma viride, Trichoderma virens, Trichoderma polysporum polysporum, Trichoderma harzianum rifai, Trichoderma lignoran, tricyclazole, triticonazole, tridemorph, triflumizole, trifloxystrobin, triforine, tolylfluanid, tolclofos methyl -methyl), tolnifanide, tolprocarb, nabam, natamycin, naftifine, nitrapyrin, nitrothal-isopropyl, nuarimol, copper nonylphenolsulfonate nonyl phenol sulphonate), Paenibacillus polymyxa, Burkholderia cepacia, Bacillus amyloliquefaciens, Bacillus simplex, Bacillus subtilis (strain: QST 713), Bacillus pumilus,
Bacillus mycoides, Bacillus licheniformis, harpin protein, Variovorax paradoxus, validamycin, valifenalate, Pantoea agglomerans, picarbutrazox, bixafen, picoxystrobin, Pythium oligandrum oligandrum, pydiflumetofen, bitertanol, binapacryl, hinokitiol, non-pathogenic Erwinia carotovora, non-pathogenic Rhizobium vitis vitis), biphenyl, piperalin, hymexazol, pyraoxystrobin, pyraclostrobin, pyraziflumid, pyrazophos, pyrapropoyne, pyrametostrobin, pyriophenone, pyri Lisoxazole, pyridaclomethyl, pyrifenox, pyributicarb, pyribencarb, pyrimethanil, pyroquilon, vinclozolin, ferbam, famoxadone, phenazine oxide oxid, fenamidone, phenaminestrobin, fenarimol, fenoxanil, ferimzone, fenpiclonil, fenpicoxamid, fenpyrazamine, fenbuconazole, fenfuram, fenpropidin, fenpropimorph, fenhexamid, folpet, phthalide, Fusarium oxysporum oxysporum, bupirimate, fuberidazole, blasticidin-S, furametpyr, furalaxyl, furanocarboxylic acid acid), fluazinam, fluindapyr, fluoxastrobin, fluoxapiprolin, fluoxythioconazole, fluopicolide, fluopimomide, fluopyram, fluorimide, fluxapyroxad, fluquinconazole, fluconazole-cis (furconazole-cis), fludioxonil, flusilazole, flusulfamide, flutianil, flutolanil, flutriafol, flufenoxadiazam, flufenoxystrobin, flubeneteram, flumethylsulforim, flumetover, flumorph, Phlebiopsis gigantea gigantea), proquinazid, prochloraz, procymidone, prothiocarb, prothioconazole, bronopol, propamocarb-hydrochloride, propico propiconazole, propineb, probenazole, bromuconazole, flometoquin, florylpicoxamid, hexaconazole, benalaxyl, benalaxyl. M (benalaxyl-M), benodanil, benomyl, pefurazoate, penconazole, pencycuron, benzovindiflupyr, benthiazole, benthiavalicarb-isopropyl nthiavalicarb-isopropyl, penthiopyrad, penflufen, boscalid, fosetyl (containing salts of aluminum, calcium, sodium, etc.), polyoxin, polycarbamate, Bordeaux mixture, mancopper, mancozeb, mandipropamid, mandestrobin, maneb, myclobutanil, mineral oil oils), mildiomycin, methasulfocarb, metam, metalaxyl, metalaxyl-M, metharylpicoxamide, metiram, methyltetraprole, metconazole, Metominostrobin, metrafenone, mepanipyrim, mefentrifluconazole, meptyldinocap, mepronil, iodocarb, laminarin, phosphorous acid and salts acids and salts, basic copper chloride, silver, copper(II) acetate, cuprous oxide, cupric hydroxide, potassium bicarbonate, sodium bicarbonate, sulfur,
Oxyquinoline sulfate, copper sulfate, (3,4-dichloroisothiazol-5-yl)-methyl-4-(tert-butyl)benzoate (chemical name, CAS registration number: 1231214-23-5), BAF-045 (code number), BAG-010 (code number), UK-2A (code number), dodecylbenzenesulfonic acid bisethylenediamine copper complex salt [II] (DBEDC), triphenyltin acetate (TPTA), triphenyltin chloride tetrafluoroethylene (TPTC), triphenyltin hydroxide (TPTH), 6-chloro-N-[2-(2,4-dimethylphenyl)-2,2-difluoro-ethyl]-3-[3-(trifluoromethyl)phenoxy]pyridazine-4-carboxamide (6-chloro-N-[2-(2,4-dimethylphenyl)-2,2-difluoro-ethyl]-3-[3-(trifluoromethyl)phenoxy]pyridazine-4-carboxamide rboxamide) (chemical name, CAS registration number: 2435594-93-5) (International Publication No. 2020/109391), 3-(3-(3-cyclopropyl-2-fluorophenoxy)-6-methylpyridazin-4-yl)-5-(2,4-dimethylbenzyl)-5,6-dihydro-4H-1,2,4-oxadiazine (3-(3-(3-cyclopropyl-2-fluorophenoxy)-6-methylpyridazin-4-yl) -5-(2,4-dimethylbenzyl)-5,6-dihydro-4H-1,2,4-oxadiazine) (chemical name, CAS registration number: 2446124-49-6) (WO 2020/127780), racemic-3-[6-chloro-3-[3-(trifluoromethyl)phenoxy]pyridazin-4-yl]-5-[(2,4-dimethylphenyl)methyl]-5,6-dihydro-4H-1,2,4-oxadiazine (rac-3-[6 -chloro-3-[3-(trifluoromethyl)phenoxy]pyridazin-4-yl]-5-[(2,4-dimethylphenyl)methyl]-5,6-dihydro-4H-1,2,4-oxadiazine) (chemical name, CAS registration number: 2446124-68-9) (WO 2020/127780), 3-(3-(3-chloro-2-fluorophenoxy)-6-methylpyridazin-4-yl)- 5-(2-chloro-4-methylbenzyl)-5,6-dihydro-4H-1,2,4-oxadiazine (3-(3-chloro-2-fluorophenoxy)-6-methylpyridazine-4-yl)-5-(2-chloro-4-methylbenzyl)-5,6-dihydro-4H-1,2,4-oxadiazine) (chemical name, CAS registration number: 2446129-82-2) (International Publication No. WO 2020/127780) Report on the synthesis of 6-chloro-3-(3-cyclopropyl-2-fluorophenoxy)-N-(2-(2,4-dimethylphenyl)-2,2-difluoroethyl)-5-methylpyridazine-4-carboxamide de) (chemical name, CAS registration number: 2435604-64-9) (International Publication No. 2020/109391), 6-chloro-N-[2-(2,4-dimethylphenyl)-2,2-difluoroethyl]-5-methyl-3-[3-(trifluoromethyl)phenoxy]pyridazine-4-carboxamide (6-chloro-N-[2-(2,4-dimethylphenyl)-2,2-difluoroethyl]-5-methyl-3-[3-(trifluoromethyl)phenoxy]pyridazine-4-carboxamide 6-chloro-N-[2-(2,4-dimethylphenyl)ethyl]-3-[3-(trifluoromethyl)phenoxy]pyridazine-4-carboxamide (chemical name, CAS registration number: 2435603-06-6) (International Publication No. 2020/109391), 6-chloro-N-[2-(2,4-dimethylphenyl)ethyl]-3-[3 -(trifluoromethyl)phenoxy]pyridazine-4-carboxamide) (chemical name, CAS registration number: 2435600-09-0) (International Publication No. 2020/109391), 6-chloro-N-[2-(2,4-dimethylphenyl)ethyl]-5-methyl-3-[3-(trifluoromethyl)phenoxy]pyridazine-4-carboxamide (6-chloro-N-[2-(2,4-dimethylphenyl)ethyl] racemic-3-[6-chloro-5-methyl-3-[3-(trifluoromethyl)phenoxy]pyridazine-4-yl]-5-[(2,4-dimethylphenyl)methyl]-5,6-dihydro-4H-1 , 2,4-oxadiazine (rac-3-[6-chloro-5-methyl-3-[3-(trifluoromethyl)phenoxy]pyridazine-4-yl]-5-[(2,4-dimethylphenyl)methyl]-5,6-dihydro-4H-1,2,4-oxadiazine) (chemical name, CAS registration number: 2446123-98-2) (International Publication No. 2020/127780), N'-(2-chloro-4- N'-(2-chloro-4-(2-fluorophenoxy)-5-methylphenyl)-N-ethyl-N-methylformimidamide (chemical name, CAS registration number: 2055756-21-1) (International Publication No. 2016/202742) (abbreviated code: E1), 2-(difluoromethyl)-N-(1,1-dimethyl- 2-(difluoromethyl)-N-(1,1-dimethyl-3-propyl-2,3-dihydro-1H-inden-4-yl)nicotinamide (chemical name, CAS registration number: 1847460-05-2) (International Publication No. 2015/197530) (abbreviated code: E2), 2-(difluoromethyl)-N-[(3R)-2,3-dihydro- 2-(difluoromethyl)-N-[(3R)-2,3-dihydro-1,1-dimethyl-3-propyl-1H-inden-4-yl]nicotinamide (chemical name, CAS registration number: 1952306-00-1) (International Publication No. 2016/096849) (abbreviated code: E2'), 2-(6-(4-chlorophenoxy)-2- (Trifluoromethyl)pyridin-3-yl)-1-(1H-1,2,4-triazol-1-yl)propan-2-ol (2-(6-(4-chlorophenoxy)-2-(trifluoromethyl)pyridin-3-yl)-1-(1H-1,2,4-triazol-1-yl)propan-2-ol) (chemical name, CAS registration number: 2082660-27-1) (WO 2017/029179) (abbreviated code: E3).

[Plant growth regulating active ingredient]
1-naphthylacetamide, 1-methylcyclopropene, 1,3-diphenylurea, 2,3,5-triiodobenzoic acid -triiodobenzoic acid), 2-methyl-4-chlorophenoxybutyric acid (MCPB) [including sodium salt, ethyl ester, etc.], 2-(naphthalene-1-yl)acetamide , 2,6-diisopropylnaphthalene, 3-[(6-chloro-4-phenylquinazoline-2-yl) 3-[(6-chloro-4-phenylquinazolin-2-yl)amino]propane-1-ol, 4-oxo-4-(2-phenylethyl)aminobutyric acid ( Chemical name, CAS registration number: 1083-55-2), 4-chlorophenoxyacetic acid (4-CPA), 5-aminolevulinic acid hydrochloride (5-aminolevulinic acid hydrochloride), methyl 5-(trifluoromethyl)benzo[b]thiophene-2-carboxylate, AVG (aminoethoxyvinylglycine), n-decyl alcohol ( n-decanol), anisiflupurin, aviglycine, ancymidol, abscisic acid, isoprothiolane, inabenfide, indole acetic acid, indole Butyric acid (indole butyric acid, uniconazole, uniconazole-P, Ecolyst, ethychlozate, ethephon, epicholeone, calcium chloride, choline chloride chloride), oxine sulfate, opabactin, kinetin, calcium peroxide, carbone, calcium formate formate), quinabactin, cloxyfonac, cloxyfonac potassium salt, cloprop, chlormequat, chlormequat chloride, choline ), cytokinins, oxidized glutathione, cyanamide, sodium cyanate cyanate), cyclanilide, dichlorprop (including salts such as dimethylammonium, potassium, sodium, choline, etc., or esters such as butotyl ester, 2-ethylhexyl ester, isoctyl ester, methyl ester, etc.); Dichlorprop-P [including salts such as sodium, potassium, dimethylammonium, or 2-ethylhexyl ester], diquat, diquat dibromide, dikegulac, gibberellin Gibberellin acid, gibberellin A4, gibberellin A7 A7), dimethipin, sintofen, jasmone, cis-jasmone, jasmonic acid, methyl jasmonate, streptomycin, lime sulfur ( calcium polysulfide), daminozide, thidiazuron, decan-1-ol, triacontanol, triapenthenol, trinexapac-ethyl , tribufos, paclobutrazol, paraffin, bispyribac-sodium, hymexazol, butralin, fluthiacet-methyl, pyraflufen Ethyl (p yraflufen-ethyl), flumetralin, flurprimidol, flurenol, pronitridine, prohydrojasmon, prohexadione-calcium salt, heptamaloxyloglucan (heptamaloxyloglucan), 6-benzylaminopurine, pendimethalin, forchlorfenuron, formononetin, maleic acid hydrazide hydrazide), mepiquat chloride, mefluidide, lipochitooligosaccharides (e.g., lipochitooligosaccharides SP104), calcium sulfate.

Furthermore, the agricultural and horticultural pest control agent of the present invention can be optionally blended with one or more types of phytotoxicity-reducing components. Examples of phytotoxicity-reducing components that can be blended are described below, but the present invention is not limited to these phytotoxicity-reducing components.

[Drug-damage reducing ingredients]
Isoxadifen, isoxadifen-ethyl, oxabetrinil, octane-1,8-diamine, cloquintocet, cloquintocet-mexyl, dietholate, cyometril, dichlormid, dicyclonone, cyprosulfamide, daimuron, naphthalic anhydride (1,8-Naphthalic Anhydride, fenchlorazole, fenchlorazole-ethyl, fenclorim, furilazole, fluxofenim, flurazole, benoxacor, metcamifen, mephenate, mefenpyr, mefenpyr-ethyl, mefenpyr-diethyl, lower alkyl substituted benzoic acid, 2,2-dichloro-N-(1,3-diethyl) xolane-2-ylmethyl)-N-(2-propenyl)acetamide (PPG-1292), 2-dichloromethyl-2-methyl-1,3-dioxane (MG-191), 3-dichloroacetyl-2,2,5-trimethyl-1,3-oxazolidine (R-29148), 4-dichloroacetyl-1-oxa-4-azaspiro[4.5]decane (AD-67), 4-carboxy-3,4-dihydro-2H-1-benzopyran-4-acetic acid (CL-304415, code number), MON4660 (code number), N1,N2-diallyl-N2-dichloroacetylglycinamide (DKA-24, code number), 1-bromo-4-[(chloromethyl)sulfonyl]benzene (CSB), 2-propenyl 1-Oxa-4-azaspiro[4,5]decane-4-carbodithioate (MG-838, code number), 3-(dichloroacetyl)-2,2-dimethyl-1,3-oxazolidine (R-28725, code number), 1-(dichloroacetyl)azepane (TI-35, code number).

The agricultural and horticultural pest control agent of the present invention is generally used in a formulation that is convenient for use, in accordance with the information on the pesticide formulation.

For example, it can be formulated into any dosage form, such as a liquid, emulsifiable concentrate, hydrated powder, water-soluble powder, hydrated granule, dust, powder granule, microgranule, oil, flowable, emulsion suspension, granule, tablet, jumbo, microemulsion, suspoemulsion, micro-dust, microcapsule, aerosol, bait, cyclodextrin, paste, seed coating agent, fumigant, smoke agent, Mamebu (registered trademark), etc.

In the agricultural and horticultural pest control agent of the present invention, the content of the above-mentioned additive components other than the active ingredient varies depending on the type or content of the active ingredient, or the formulation type, but is usually about 0.001 to 99.9% by mass, and preferably about 1 to 99% by mass. Specifically, based on the total amount of the composition, the carrier is usually 5 to 95% by mass, and preferably 20 to 90% by mass, the surfactant is usually 0.1 to 30% by mass, and preferably 0.5 to 10% by mass, and the other additive components are usually in the range of 0.001 to 30% by mass, and preferably 0.01 to 10% by mass.

The content of the compound having plant disease resistance inducing activity, which is the active ingredient in the agricultural and horticultural pest control agent of the present invention, is usually about 0.1 to 80% by mass based on the total amount of the agricultural and horticultural pest control agent. For example, when used as a liquid agent, emulsion, hydrated agent, water-soluble agent, granular hydrated agent, emulsion suspension, flowable agent, microemulsion agent, suspoemulsion agent, etc., the content is preferably about 1 to 80% by mass, more preferably about 10 to 50% by mass. For example, when used as an oil agent, dust agent, dust granule agent, fine granule agent, etc., the content is preferably about 0.1 to 50% by mass, more preferably about 0.1 to 20% by mass. For example, when used as a granule agent, tablet, jumbo agent, Mame-tsubu (registered trademark), etc., the content is preferably about 0.5 to 50% by mass, more preferably about 0.5 to 20% by mass.

When used, the agricultural and horticultural pest control agent of the present invention may be applied directly or diluted or suspended to a concentration appropriate for the purpose of use. In the pest control method of the present invention, a compound having plant disease resistance induction activity may be applied to a useful plant, specifically to the above-ground parts, below-ground parts or seeds of a useful plant, or to a location where a useful plant is to be grown or where a useful plant is growing, for example, by foliage spray, seed application, soil application or water surface application. In addition, in the pest control method of the present invention, there is no limit to the amount of the compound applied to a useful plant, but it can usually be applied in the range of 0.1 to 5000 mg, preferably 0.1 to 1000 mg, per plant body.

The agricultural and horticultural pest control agent of the present invention can be applied by the application method generally used.

Examples of such applications include spraying (e.g., spraying, misting, atomizing, dusting, granules, water surface application, box application, etc.), soil application (e.g., soil irrigation, soil mixing, bed soil mixing, seedling box treatment, top dressing, seedbed treatment, plant base treatment, planting furrow treatment, crop row treatment, side row application, etc.), seed application (e.g., seed dressing, seed smearing, seed soaking, seed covering, calper treatment, etc.), and application to solutions such as hydroponics. The "seeds" used for seed application refer to plant bodies in the early stages of cultivation used for plant propagation, and include, for example, seeds, bulbs, tubers, tuberous roots, sprouts, bulbils, bulbs, or plant bodies for vegetative propagation. Other examples of applications include, but are not limited to, soaking, trunk irrigation, trunk application, poison bait, fertilizer mixing, smoking, bait, application to building materials, or mixing with irrigation water.

When the agricultural and horticultural pest control agent of the present invention is applied to seeds, it may be applied at any time before planting them. When applied to soil, it is effective to apply it before sowing, at the time of sowing, during the seedling raising period, or when the seedlings are planted, but it can also be applied during the growth period after planting. When applied by spraying, it may be applied during the seedling raising period or during the growth period in the actual field.

The amount of the active ingredient used in the present invention is usually 0.1 to 100,000 g per hectare, preferably 1 to 5,000 g, but is not limited to this amount.

In seed treatment, the amount of active ingredient used is usually in the range of 0.01% to 50% by mass relative to the mass of the seed, but is not limited to this range. In addition, the amount of active ingredient used per plant seed is 0.01 to 10 mg, preferably 0.1 to 5 mg, but is not limited to this range.

When treating seedlings or planting holes, the amount of active ingredient used per plant is 0.1 to 5000 mg, preferably 1 to 1000 mg, but is not limited to these amounts.

When used after diluting with water, the concentration of the active ingredient is usually 0.1 to 50,000 ppm, but is not limited to this.

In addition, the concentration of the active ingredient can be changed appropriately depending on the formulation form, application method, purpose, timing, location, and occurrence of pests, etc.

Useful plants that can be treated with the agricultural and horticultural pest control agent of the present invention are not particularly limited, but include, for example, cereals (rice, barley, wheat, rye, oats, corn, etc.), beans (soybeans, adzuki beans, broad beans, peas, kidney beans, peanuts, etc.), fruit trees and fruits (apples, citrus fruits, pears, grapes, peaches, plums, cherries, chestnuts, almonds, bananas, etc.), leafy vegetables and fruit vegetables (cabbage, tomatoes, spinach, broccoli, lettuce, onions, leeks, peppers, eggplants, strawberries, peppers, okra, etc.), root vegetables (carrots, potatoes, sweet potatoes, taro, radishes, turnips, lotus roots, burdock, garlic, etc.), crops for processing (cotton, hemp, beets, hops, sorghum, etc.), and the like. cane, sugar beet, olive, rubber, coffee, tobacco, tea, etc.), melons (pumpkin, cucumber, watermelon, Japanese melon, melon, etc.), pasture grasses (orchard grass, sorghum, timothy, clover, alfalfa, etc.), turf grasses (Korean grass, bentgrass, etc.), aromatic and spice plants (lavender, rosemary, thyme, parsley, pepper, ginger, etc.), ornamental plants (asparagus, green necklace, goldcrest, table palm, horsetail, etc.), flowers (chrysanthemum, rose, carnation, orchid, etc.), garden trees (ginkgo, cherry, aucuba, etc.), forest trees (abies, spruce, pines, Japanese cypress, cedar, cypress, etc.), etc.

The above "useful plants" include herbicide-resistant crops, pest-resistant crops incorporating insecticidal protein-producing genes, disease-resistant crops incorporating genes that produce disease-resistance inducers, crops with improved taste, crops with improved shelf life, and crops with improved yields, all of which have been created using new breeding techniques (New Plant Breeding Techniques, NBTs) that combine traditional breeding techniques with molecular biological methods, genetic engineering techniques, or existing crossbreeding techniques.

Examples of "useful plants" that have been given resistance through classical breeding methods include rapeseed, wheat, sunflower, rice, and corn that are resistant to imidazolinone ALS inhibitor herbicides such as imazethapyr, which are already sold under the name Clearfield (registered trademark). Similarly, there are soybeans that are resistant to sulfonylurea ALS inhibitor herbicides such as thifensulfuron-methyl, which are already sold under the name STS soybean. Similarly, an example of a useful plant that has been given resistance to acetyl-CoA carboxylase inhibitors such as trione oxime and aryloxyphenoxypropionic acid herbicides is SR corn. Useful plants that have been given resistance to acetyl-CoA carboxylase inhibitors are described in Proceedings of the National Academy of Sciences of the United States of America (Proc. Natl. Acad. Sci. USA) Vol. 87, pp. 7175-7179 (1990), etc. In addition, mutant acetyl-CoA carboxylases that are resistant to acetyl-CoA carboxylase inhibitors have been reported in Weed Science Vol. 53, pp. 728-746 (2005), etc., and plants that are resistant to acetyl-CoA carboxylase inhibitors can be produced by introducing such mutant acetyl-CoA carboxylase genes into plants using recombinant gene technology or by introducing a mutation related to resistance into crop acetyl-CoA carboxylase.

Furthermore, by introducing a nucleic acid that introduces a base substitution mutation, such as that typified by the chimeraplasty technique (Gura T. 1999. Repairing the Genome's Spelling Mistakes. Science 285: 316-318), into a plant cell to induce site-specific amino acid substitution mutations in the plant's acetyl-CoA carboxylase gene, ALS gene, etc., it is possible to create plants that are resistant to acetyl-CoA carboxylase inhibitors, ALS inhibitors, etc., and the agricultural and horticultural pest control agent of the present invention can be used on these plants as well.

Examples of useful plants that have been made resistant through genetic engineering include glyphosate-resistant corn, soybean, cotton, rapeseed, and sugar beet varieties, which are already sold under the trade names Roundup Ready (registered trademark) and Agrisure GT (registered trademark). Similarly, there are glufosinate-resistant corn, soybean, cotton, and rapeseed varieties that have been made resistant through genetic engineering, which are already sold under the trade name Liberty Link (registered trademark). Similarly, bromoxynil-resistant cotton made through genetic engineering is already sold under the trade name BXN.

Furthermore, toxins expressed in genetically modified plants include, for example, insecticidal proteins derived from Bacillus cereus or Bacillus popilliae; δ-endotoxins such as Cry1Ab, Cry1Ac, Cry1F, Cry1Fa2, Cry2Ab, Cry3A, Cry3Bb1 or Cry9C derived from Bacillus thuringiensis, insecticidal proteins such as VIP1, VIP2, VIP3 or VIP3A; insecticidal proteins derived from nematodes; toxins produced by animals such as scorpion toxins, spider toxins, wasp toxins or insect-specific neurotoxins; fungal toxins; plant lectins; aggregating toxins; These include thymine; protease inhibitors such as trypsin inhibitors, serine protease inhibitors, patatin, cystatin, and papain inhibitors; ribosome-inactivating proteins (RIPs) such as ricin, corn-RIP, abrin, saporin, and bryodin; steroid metabolic enzymes such as 3-hydroxysteroid oxidase, ecdysteroid-UDP-glucosyltransferase, and cholesterol oxidase; ecdysone inhibitors; HMG-CoA reductase; ion channel inhibitors such as sodium channel inhibitors and calcium channel inhibitors; juvenile hormone esterase; diuretic hormone receptor; stilbene synthase; bibenzyl synthase; chitinase; and glucanase.

Furthermore, toxins expressed in such genetically modified plants include hybrid toxins, partially deleted toxins, and modified toxins made from delta-endotoxin proteins such as Cry1Ab, Cry1Ac, Cry1F, Cry1Fa2, Cry2Ab, Cry3A, Cry3Bb1, or Cry9C, and insecticidal proteins such as VIP1, VIP2, VIP3, or VIP3A. Hybrid toxins are produced by using recombinant technology to create new combinations of different domains of these proteins. One known example of a partially deleted toxin is Cry1Ab, which has a partial deletion in its amino acid sequence. Modified toxins are those in which one or more amino acids of the natural toxin have been replaced.

Examples of these toxins and recombinant plants capable of synthesizing these toxins are described in patent documents such as EP-A-0374753, WO93/07278, WO95/34656, EP-A-0427529, EP-A-451878, and WO03/052073. The toxins contained in these recombinant plants confer resistance to pests of the order Coleoptera, Diptera, and Lepidoptera, among others. The agricultural and horticultural pest control agent of the present invention can also be used in combination with or systematized with these technologies.

In addition, genetically modified plants that contain one or more insecticidal pest resistance genes and express one or more toxins are already known, and some are commercially available. Examples of these genetically modified plants include YieldGard® (a corn variety expressing the Cry1Ab toxin), YieldGard Rootworm® (a corn variety expressing the Cry3Bb1 toxin), YieldGard Plus® (a corn variety expressing both the Cry1Ab and Cry3Bb1 toxins), Herculex I® (a corn variety expressing the Cry1Fa2 toxin and phosphinothricin N-acetyltransferase (PAT) to confer resistance to glufosinate), NuCOTN33B® (a cotton variety expressing the Cry1Ac toxin), Bollgard I (a corn variety expressing the Cry1Ab toxin), Bollgard I (a corn variety expressing the Cry1Ab toxin), Bollgard I (a corn variety expressing the Cry1Ab toxin), Bollgard I (a corn variety expressing the Cry1Ab toxin), Bollgard I (a corn variety expressing the Cry1Ab toxin), Bollgard I (a corn variety expressing the Cry1Ab toxin), Bollgard I (a corn variety expressing the Cry3Bb1 ... These include NatureGard I (registered trademark) (cotton variety expressing Cry1Ac toxin), Bollgard II (registered trademark) (cotton variety expressing Cry1Ac and Cry2Ab toxins), VIPCOT (registered trademark) (cotton variety expressing VIP toxin), NewLeaf (registered trademark) (potato variety expressing Cry3A toxin), NatureGard Agrisure GT Advantage (GA21 glyphosate tolerance trait), Agrisure CB Advantage (Bt11 corn borer (CB) trait), Protecta (registered trademark), etc.

The above useful plants also include those that have been given the ability to produce anti-pathogenic substances with selective action using genetic engineering techniques.

Examples of antipathogenic substances include PR proteins (PRPs, described in EP-A-0392225); ion channel inhibitors such as sodium channel inhibitors and calcium channel inhibitors (virus-produced toxins such as KP1, KP4, and KP6 are known); substances produced by microorganisms such as stilbene synthase, bibenzyl synthase, chitinase, glucanase, peptide antibiotics, antibiotics with heterocycles, and protein factors involved in plant disease resistance (called plant disease resistance genes, described in WO03/000906). Such antipathogenic substances and genetically modified plants that produce them are described in EP-A-0392225, WO95/33818, EP-A-0353191, etc.

The above useful plants also include crops that have been given useful traits, such as improved oil content or increased amino acid content, using genetic engineering technology. Examples include VISTIVE (registered trademark) (low-linolene soybeans with reduced linolene content) and high-lysine (high oil) corn (corn with increased lysine or oil content).

Furthermore, stacked varieties that combine multiple of the above-mentioned classical herbicide traits or useful traits such as herbicide resistance genes, insecticide pest resistance genes, antipathogenic substance production genes, oilseed component modification traits, and amino acid content enhancement traits are also included.

The agricultural and horticultural pest control agent of the present invention is suitable for controlling various agricultural pests that damage useful plants (e.g., rice, fruit trees, vegetables, other agricultural crops, and horticultural plants such as flowers), and can also be used to control pests such as grain storage pests, livestock pests, sanitary pests, and nematodes in stored grains (e.g., rice, wheat flour, etc.).

Specific pest names for which the agricultural and horticultural pest control agent of the present invention is effective are given below as non-limiting examples.

Hemiptera pests, such as Riptortus clavatus, Nezara viridula, Lygus sp., Blissus leucopterus, Stephanitis nashi and other stink bugs (Heteroptera; Heteroptera); Leafhoppers such as Japanese leafhoppers (Empoasca sp., Erythroneura sp., Circulifer sp.), etc.; planthoppers such as brown planthopper (Nilaparvata lugens), white-backed planthopper (Sogatella furcifera), sparse brown planthopper (Laodelphax striatellus), etc.; Psylla sp. psyllids such as Bemisia tabaci and Trialeurodes vaporariorum; whiteflies such as Viteus vitifolii, Myzus persicae, Aphis pomi, Aphis gossypii, Aphis fabae, Rhopalosiphum pseudobrassicas, Japonica; Aphids such as Aulacorthum solani and Schizaphis graminum; scale insects such as Pseudococcus comstocki, Ceroplastes rubens, Comstockaspis perniciosa, and Unaspis yanonensis; Assassin bugs such as Rhodnius sp.

Lepidoptera pests, for example, tortrix moths such as Homona magnanima, Adoxophyes orana, Sparganthis pilleriana, Grapholitha molesta, Leguminivoraglycinivorella, Laspeyresia pomonella, Eucosma sp., and Lobesia botrana; slender moths such as Eupoecillia ambiguella; Bambalina sp. bagworm moths such as; broad-leaved moths such as Nemapogon granellus and Tinea translucens; leafminers such as Lyonetia prunifoliella; leafminers such as Phyllonorycter ringoniella; small leafminers such as Phyllocnistis citrella; diamondback moths such as Plutella xylostella and Prays citri; grapevine moths such as Paranthrene regalis and Synanthedon sp. clearwing moths such as Pectinophora gossypiella, Phthorimaea operaculella, Stomopteryx sp. and other gingival moths; peach fruit moths such as Carposina niponensis; Monema flavescens and other gingival moths; Chilo suppressalis, Cnaphalocrocis medinalis, Ostrinia nubilalis, Ostrinia furnacalis, and the gray spotted moth moths such as Hellula undalis, Galleria mellonella, Elasmopalpus lignosellus, and Loxostege sticky; white butterflies such as Pieris rapae; geometria such as Ascotis selenaria; Malacosoma neustria and other moths; hawk moths such as Manduca sexta; tussock moths such as Eupractis pseudoconspersa and Lymantria dispar; tiger moths such as Hyphantria cunea; tobacco budworms (Heliothis virescens), ballworms (Helicoverpa zea), and white shrike moths (Heliothis spp.). Noctuid moths such as cutworm (Spodoptera exigua), tobacco budworm (Helicoverpa armigera), common cutworm (Spodoptera litura), cutworm moth (Mamestra brassicae), cutworm moth (Agrotis ipsiron), armyworm moth (Pseudaletia separata), and nettle looper moth (Trichoplusia ni).

Coleoptera pests, for example scarab beetles such as Anomala cuprea, Popilli japonica, Anomala rufocuprea, Eutheola rugiceps, etc.; wireworms (Agriotes sp.), Conodeus sp. click beetles, etc.; ladybugs, such as the 20-spotted ladybug (Epilachna vigintioctopunctata) and the common ladybug (Epilachna varivestis); mealworms, such as the red flour beetle (Tribolium castaneum); long-horned beetle (Anoplophora Long-horned beetles such as Monochamus alternatus and Acanthoscelides obtectus; bean weevils such as Calosobruchus chinensis; Colorado potato beetle Leptinotarsa de cemlineata), corn rootworm (Diabrotica sp.), rice leaf beetle (Oulema oryzae), rice leaf beetle (Chaetocnema concinna), Phaedon cochlearias, Oulema melanopus, Dicladispa armigera, and other leaf beetles; Weevils such as Apion godmani; weevils such as Lissorhoptrus oryzophilus and Anthonomus grandis; weevils such as Sitophilus zeamais; bark beetles; dermestid beetles; and rice beetles.

Diptera pests, such as Tipra ano, Tanytarsus oryzae, Orseolia oryzae, Ceratitis capitata, Hydrellia griseola, Drosophila suzukii, Oscinella frit, Chlorops oryzae, Ophiomyia phaseoli, Liriope gracilis, omyza trifolii), red larvae fly (Pegomya hyoscyami), seed fly (Hylemiaplatura), sorghum fly (Atherigona soccata), house fly (Musca domestica), horse fly (Gastrophilus sp.), stable fly (Stomoxys sp.), nettle mosquito (Aedes aegypti), Culex pipiens, Anopheles slnensis, Culex tritaeniorhynchus, etc.

Hymenoptera pests, such as wasps (Cephus sp.); hornet wasps (Harmolita sp.); sawflies (Athalia sp.); hornets (Vespa sp.); fire ants, etc.

Orthoptera pests, such as the German cockroach (Blatella germanica), the American cockroach (Periplaneta americana), the mole cricket (Gryllotalpa africa), the grasshopper (Locusta migratoria migratoriodes), Melanoplus sanguinipes, etc.

Termite pests, such as the Japanese termite (Reticulitermessperatus), Formosan termite (Coptotermes formosanus), etc.

Thysanoptera pests, for example, onion thrips (Thrips tabaci Lindeman), tea tree thrips (Scirtothrips dorsalis), southern green thrips (Thrips palmi), croton thrips (Heliothrips haemorrhoidalis), western flower thrips (Frankliniella occidentalis), rice thrips (Haplothrips aculeatus), etc.

Acari pests, such as Tetranychus urticae, Tetranychus kanzawai, Panonychus citri, Panonychusulmi, Eotetranychus carpini, and Eotetranychus sulmi. s banksi), citrus rust mite (Phyllocoptruta oleivora), tea dust mite (Polyphagotarsonemus latus), small spider mite (Brevipalpus sp.), Robin mite (Rhizoglyphus robini), and spider mites such as Tyrophagus putrescentiae.

Plant-parasitic nematodes, such as Meloidogyne incognita, Pratylenchus sp., Heterodera glycines, Aphelenchoides besseyi, Bursaphelenchus xylophilus, Radopholus similis, Ditylenchus dipsaci), Tylenchulus semipenetrans, Globodera spp., Meloidogyne spp., Aphelenchoides spp., Longidorus spp., Xiphiinema spp., Trichodorus spp., Bursaphelenchus spp., etc.

Other harmful animals, nuisance animals, sanitary pests, parasites, for example, gastropoda such as apple snails (Pomacea canaliculata), slugs (Incilaria sp.), African snails (Achatina fulica), etc.; isopods such as pillbugs (Armadillidium sp.), woodlouses, centipedes, etc.; booklice such as Liposcelis sp.; silverfish such as Ctenolepisma sp.; fleas such as Pulex sp., Ctenocephalides sp.; biting lice such as Trichodectes sp.; Cimex sp. bedbugs such as; animal parasitic mites such as cow tick (Boophilus microplus) and Haemaphysalis longicornis; house dust mites, etc.

The agricultural and horticultural pest control agent of the present invention is preferably used against sap-sucking pests such as Hemiptera and Thripidae, and Lepidoptera pests, among the above pests, and is particularly preferably used against whitefly pests such as Bemisia tabaci and Trichoderma greenhousea, aphid pests such as Myzus persicae and Aphis gossypii, and also against Thrips palmi, Thrips citri, Thrips tabaci, Diamondback moth, Helicoverpa armigera, Spodoptera litura, and Rice leafroller. The agricultural and horticultural pest control agent of the present invention is also highly effective against pests that have acquired drug resistance.

Below, examples of the present invention are given, but the types and blending ratios of the compounds and additives are not limited to these and can be changed over a wide range. In the following explanation, "parts" refers to parts by mass.

Formulation Example 1 Granules Diclobentazox 2 parts Sodium salt of lauryl alcohol sulfate 2 parts Sodium lignin sulfonate 5 parts Carboxymethylcellulose 2 parts Clay 89 parts The above ingredients were uniformly mixed and pulverized. To this mixture was added an amount of water equivalent to 20 parts, kneaded, processed into granules of 14 to 32 mesh using an extrusion granulator, and then dried to obtain granules.

Formulation Example 2 Flowable formulation Diclobentazox 10 parts Polyoxyethylene styrenated phenyl ether sulfate 4 parts Ethylene glycol 7 parts Silicone AF-118N (manufactured by Asahi Chemical Industry Co., Ltd.) 0.02 parts Water 78.98 parts The above ingredients were mixed for 30 minutes using a high-speed mixer, and then pulverized using a wet pulverizer to obtain a flowable formulation.

Formulation Example 3 Flowable agent Diclobentazox 40 parts Polyoxyethylene styrenated phenyl ether sulfate 4 parts Ethylene glycol 7 parts Silicone AF-118N (manufactured by Asahi Chemical Industry Co., Ltd.) 0.02 parts Water 48.98 parts The above ingredients were mixed for 30 minutes using a high-speed mixer, and then pulverized using a wet pulverizer to obtain a flowable agent.

Formulation Example 4 Granules Diclobentazox 1 part Isotianil 1 part Sodium salt of lauryl alcohol sulfate 2 parts Sodium lignin sulfonate 5 parts Carboxymethylcellulose 2 parts Clay 89 parts The above ingredients were uniformly mixed and pulverized. To this mixture was added an amount of water equivalent to 20 parts, kneaded, processed into granules of 14 to 32 mesh using an extrusion granulator, and then dried to obtain granules.

Formulation Example 5 Wettable powder Diclobentazox 10 parts Naphthalenesulfonic acid formalin condensate sodium salt 0.5 parts Polyoxyethylene alkylaryl ether 0.5 parts Diatomaceous earth 30 parts Clay 59 parts The above ingredients were uniformly mixed and pulverized to give wettable powder.

[Formulation Example 6] Water dispersible granule Diclobentazox 20 parts Sodium lignin sulfonate 5 parts Polyoxyethylene alkylaryl ether 1 part Sodium polycarboxylate 3 parts White carbon 5 parts Pregelatinized starch 1 part Calcium carbonate 45 parts Water 20 parts The above ingredients were mixed and kneaded to form granules. The resulting granules were dried in a fluidized bed dryer to obtain a water dispersible granule.

Next, the effects of the agricultural and horticultural pest control agent of the present invention will be explained using test examples.

[Test Example 1] Control effect against Bemisia tabaci A No. 5 unglazed pot was filled with horticultural soil, a predetermined amount of each agent was applied to the planting hole and mixed, and a tomato seedling (variety: Momotaro) in the sixth compound leaf development stage was planted (hereinafter also referred to as the treatment area). The granules containing diclobentazox were produced according to the above-mentioned Formulation Example 1, and the isotianil granules or probenazole granules were commercially available (Routine granules (manufactured by Bayer Crop Science Co., Ltd.), Oryzemate 1 kg granules (manufactured by Hokko Chemical Industry Co., Ltd.)). 15 days after planting, adult Bemisia tabaci were released. 25 days after planting, two leaflets were cut from each of the fourth, fifth, and sixth leaves, and the number of parasitic eggs and larvae was counted. Similarly, 30 days after planting, two leaflets were cut from the 5th, 6th, and 7th compound leaves, and 35 days after planting, two leaflets were cut from the 6th, 7th, and 8th leaves, and the number of parasitic eggs and larvae was counted. For tomato seedlings not treated with any drug (hereinafter also referred to as the untreated group), the number of Bemisia tabaci eggs and larvae was counted in the same manner as above, and the control value was calculated from [Number I]. The test results are shown in Tables 1 to 3.

[Number I]
Control value = [1 - (number of parasites (eggs + larvae) in treated area / number of parasites (eggs + larvae) in untreated area)] x 100

As a result, it became clear that the agricultural and horticultural pest control agent of the present invention has effective control activity against Bemisia tabaci.

[Test Example 2] Control effect against Bemisia tabaci A 5-size unglazed pot was filled with horticultural soil, a predetermined amount of each agent was applied to the planting hole, and mixed, and a cucumber seedling (variety: Sagami Hanshiro) in the second true leaf development stage was planted (hereinafter also referred to as the treated area). The granules containing diclobentazox were produced according to the above-mentioned Preparation Example 1, and a commercially available agent (Oryzemate 1 kg granules (manufactured by Hokko Chemical Industry Co., Ltd.)) was used as the probenazole granules. 14 days after planting, adult Bemisia tabaci were released. 24 days after planting, two leaves were hollowed out from the third, fourth, and fifth leaves with a cork borer (diameter 2 cm), and the number of parasitic eggs and larvae was counted. The number of Bemisia tabaci eggs and larvae was counted for the cucumber seedlings not treated with the agent (hereinafter also referred to as the untreated area) in the same manner as above, and the control value was calculated in the same manner as in Test Example 1. The test results are shown in Table 4.

As a result, it became clear that the agricultural and horticultural pest control agent of the present invention has effective control activity against Bemisia tabaci.

[Test Example 3] Control effect against Bemisia tabaci In this test example, a granule containing diclobentiazox produced according to Formulation Example 1 and a flowable containing diclobentiazox produced according to Formulation Example 3 were used. The above-mentioned agents were applied to tomato seedlings (variety: Momotaro) as a test crop 9 days before transplanting or on the day of transplanting according to the treatment method shown in Table 5. After treatment, the test crop was planted in a No. 7 unglazed pot and placed in a phytotron (light condition: natural light, temperature condition: constant 25°C) where adult Bemisia tabaci emerge. 12 days after planting, two leaflets were cut from each of the 5th, 6th, and 7th compound leaves, the number of parasitic Bemisia tabaci larvae was counted, and the control value was calculated according to Test Example 1. As a comparative example, the insecticide cyantraniliprole granules (trade name: Prirosso (registered trademark) granules Omega (manufactured by FMC Chemicals Co., Ltd.)) were used and the control value was calculated in the same manner. The test results are shown in Table 5.

These results demonstrate that the agricultural and horticultural pest control agent of the present invention, regardless of the formulation type or application method, exhibits a control effect against Bemisia tabaci, and has sufficient control effect compared to commercially available insecticides.

[Test Example 4] Control effect against Bemisia tabaci A 4-size unglazed pot was filled with horticultural soil, and a cucumber seedling (variety: Sagami Hanjiro) in the second true leaf development stage was planted (hereinafter also referred to as the treatment group). On the day of planting, 5 ml of a drug solution diluted to a predetermined concentration was irrigated at the base of the plant, and the pot was placed in a phytotron (light condition: natural light, temperature condition: always 25°C) where Bemisia tabaci adults are generated. The flowable agent containing diclobenziazox was produced according to the above-mentioned Formulation Example 3, and the flowable agent containing isotianil was a commercially available agent (Routine Flowable (manufactured by Bayer CropScience Co., Ltd.)). 12 days after planting, the first and second true leaves were cut off, and the number of parasitic eggs and larvae was counted under a microscope, and the control value was calculated in the same manner as in Test Example 1. The test results are shown in Table 6. As a comparative example, a fungicide, pyraziflumid wettable powder (commercially available product, trade name: Parade (registered trademark) 20 flowable (manufactured by Nihon Nohyaku Co., Ltd.)), was used to calculate the control value in the same manner. The test results are shown in Table 6.

These results demonstrate that the agricultural and horticultural pest control agent of the present invention is effective against Bemisia tabaci, but that fungicides that do not have the ability to induce plant disease resistance do not have a pest control effect.

[Test Example 5] Control effect against green peach aphid Sugar beet seeds (variety: Papirika) were smeared with a flowable formulation containing diclobentazox produced according to the above-mentioned Formulation Example 3, air-dried, and then sown in a pot filled with horticultural soil. Adult green peach aphids were released 20 days, 22 days, and 28 days after sowing, and the number of parasites was counted 35 days after sowing, and the control value was calculated according to Test Example 1. As a comparative example, the insecticide thiamethoxam flowable (trade name: Cruiser (registered trademark) 5FS (manufactured by Syngenta United States)) was used, and the control value was calculated in the same manner. The test results are shown in Table 7.

These results demonstrate that the agricultural and horticultural pest control agent of the present invention also exhibits a control effect against green peach aphids, and has sufficient control effect compared to commercially available insecticides.

[Test Example 6] Control effect against diamondback moth Cabbage (variety: Shikidori) in the fifth true leaf development stage was irrigated with a flowable agent containing diclobentazox produced according to the above-mentioned Formulation Example 3, and placed in a phytotron (light conditions: natural light, temperature conditions: always 25°C). 10 days after the drug treatment, diamondback moth adults were released, and 14 days after the release, the number of diamondback moth larvae parasitizing the test crop was counted, and the control value was calculated according to Test Example 1. As a comparative example, the insecticide Cyantraniliprole wettable powder (trade name: Verimark (registered trademark) SC (manufactured by FMC Chemicals Co., Ltd.)) was used, and the control value was calculated in the same manner. The test results are shown in Table 8.

These results demonstrate that the agricultural and horticultural pest control agent of the present invention also exhibits a control effect against diamondback moths, and has sufficient control effect compared to commercially available insecticides.

[Test Example 7] Control effect against rice leafroller The base of rice plants at the time of transplantation was treated with a granule containing diclobentazox produced according to the above-mentioned Formulation Example 1, and then transplanted into a pot. Adult rice leafrollers were released every 7 days from 35 days after transplantation, and 42 days after the start of release, the total number of rice leaves and the number of damaged leaves were counted, the damaged leaf rate was calculated, and the control value was calculated from [Number II]. The test results are shown in Table 9.
[Mathematics II] Control value = [1 - (percentage of damaged leaves in treated area) / (percentage of damaged leaves in untreated area)] x 100

From these results, it became clear that the agricultural and horticultural pest control agent of the present invention also exhibits a control effect against the rice leafroller.

Claims (13)

An agricultural and horticultural pest control agent characterized by containing, as an active ingredient, a compound having plant disease resistance induction activity. The agent according to claim 1, wherein the compound having plant disease resistance induction activity is one or more compounds selected from the group consisting of probenazole, isotianil, diclobentiazox, tiadinil and acibenzolar-S-methyl. The agent according to claim 1 or 2, which is intended for sap-sucking pests. The agent according to claim 3, wherein the sap-sucking pests are Hemiptera or Thripidae. The agent according to claim 4, wherein the Hemiptera pests are whiteflies or aphids. The agent according to claim 1 or 2, which is intended for use against lepidopteran pests. A method for controlling pests in which a compound having plant disease resistance inducing activity is applied to a useful plant, a place where a useful plant is intended to grow, or a place where a useful plant is growing. The method for controlling insects according to claim 7, wherein the compound having plant disease resistance induction activity is one or more compounds selected from the group consisting of probenazole, isotianil, diclobentiazox, tiadinil and acibenzolar-S-methyl. The method for controlling pests according to claim 7 or 8, wherein the amount of the compound having plant disease resistance inducing activity applied to a useful plant is 0.1 to 1000 mg per plant body. The method for controlling pests according to any one of claims 7 to 9, which targets sap-sucking pests. The method for controlling pests according to claim 10, wherein the sap-sucking pests are Hemiptera or Thripidae. The method for controlling insects according to claim 11, wherein the Hemiptera pests are whiteflies or aphids. The method for controlling insects according to any one of claims 7 to 9, wherein the target of control is a Lepidoptera pest.