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WO2024263796A3 - Systems and methods for implanting electrodes in the brain - Google Patents

Systems and methods for implanting electrodes in the brain Download PDF

Info

Publication number
WO2024263796A3
WO2024263796A3 PCT/US2024/034843 US2024034843W WO2024263796A3 WO 2024263796 A3 WO2024263796 A3 WO 2024263796A3 US 2024034843 W US2024034843 W US 2024034843W WO 2024263796 A3 WO2024263796 A3 WO 2024263796A3
Authority
WO
WIPO (PCT)
Prior art keywords
lead
brain
systems
stylet
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/US2024/034843
Other languages
French (fr)
Other versions
WO2024263796A2 (en
Inventor
Jared Floyd
Tanner Chas DIXON
Roshanne Malekmadani
Shashank NAGESH
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Iota Biosciences Inc
Original Assignee
Iota Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Iota Biosciences Inc filed Critical Iota Biosciences Inc
Publication of WO2024263796A2 publication Critical patent/WO2024263796A2/en
Publication of WO2024263796A3 publication Critical patent/WO2024263796A3/en
Anticipated expiration legal-status Critical
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/10—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis
    • A61B90/11—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges for stereotaxic surgery, e.g. frame-based stereotaxis with guides for needles or instruments, e.g. arcuate slides or ball joints
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/05—Electrodes for implantation or insertion into the body, e.g. heart electrode
    • A61N1/0526—Head electrodes
    • A61N1/0529—Electrodes for brain stimulation
    • A61N1/0534—Electrodes for deep brain stimulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/03—Automatic limiting or abutting means, e.g. for safety
    • A61B2090/033—Abutting means, stops, e.g. abutting on tissue or skin
    • A61B2090/034—Abutting means, stops, e.g. abutting on tissue or skin abutting on parts of the device itself
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/06—Measuring instruments not otherwise provided for
    • A61B2090/062—Measuring instruments not otherwise provided for penetration depth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/08—Accessories or related features not otherwise provided for
    • A61B2090/0807—Indication means
    • A61B2090/0811—Indication means for the position of a particular part of an instrument with respect to the rest of the instrument, e.g. position of the anvil of a stapling instrument
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605—Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606—Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36067—Movement disorders, e.g. tremor or Parkinson disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Psychology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Radiology & Medical Imaging (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Pathology (AREA)
  • Cardiology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Electrotherapy Devices (AREA)

Abstract

Provided herein are lead and stylet systems and methods of using the sty let to implant the lead into the brain. The leads may be used for deep brain stimulation (DBS) and may be connected to a cranially mounted implantable pulse generator (IPG) of a DBS sy stem. The lead may comprise a lumen configured to removably house the stylet to assist in implanting electrodes disposed on the lead in the brain. The lead and stylet systems described herein may allow for minimal excess lead length between the implantation site of the lead in the brain and the IPG (e.g., implanted in the skull).
PCT/US2024/034843 2023-06-20 2024-06-20 Systems and methods for implanting electrodes in the brain Pending WO2024263796A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202363509236P 2023-06-20 2023-06-20
US63/509,236 2023-06-20

Publications (2)

Publication Number Publication Date
WO2024263796A2 WO2024263796A2 (en) 2024-12-26
WO2024263796A3 true WO2024263796A3 (en) 2025-04-17

Family

ID=93936240

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2024/034843 Pending WO2024263796A2 (en) 2023-06-20 2024-06-20 Systems and methods for implanting electrodes in the brain

Country Status (1)

Country Link
WO (1) WO2024263796A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3906091T (en) 2019-01-04 2024-08-13 Iota Biosciences Inc Ultrasound-based protocol for operating an implantable device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6799074B1 (en) * 1999-08-18 2004-09-28 Uwe Thomas Recording Microprobe system for stereotactic neurotherapy
US7809446B2 (en) * 2005-01-05 2010-10-05 Boston Scientific Neuromodulation Corporation Devices and methods for brain stimulation
US8968331B1 (en) * 2010-04-24 2015-03-03 Jerzy Roman Sochor Implantable lead and surgical accessories
US20160121103A1 (en) * 2014-11-03 2016-05-05 Boston Scientific Neuromodulation Corporation Electrical stimulation system with anchoring stylet and methods of making and using

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6799074B1 (en) * 1999-08-18 2004-09-28 Uwe Thomas Recording Microprobe system for stereotactic neurotherapy
US7809446B2 (en) * 2005-01-05 2010-10-05 Boston Scientific Neuromodulation Corporation Devices and methods for brain stimulation
US8968331B1 (en) * 2010-04-24 2015-03-03 Jerzy Roman Sochor Implantable lead and surgical accessories
US20160121103A1 (en) * 2014-11-03 2016-05-05 Boston Scientific Neuromodulation Corporation Electrical stimulation system with anchoring stylet and methods of making and using

Also Published As

Publication number Publication date
WO2024263796A2 (en) 2024-12-26

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