[go: up one dir, main page]

WO2024245921A1 - Processus de fabrication d'une dispersion - Google Patents

Processus de fabrication d'une dispersion Download PDF

Info

Publication number
WO2024245921A1
WO2024245921A1 PCT/EP2024/064346 EP2024064346W WO2024245921A1 WO 2024245921 A1 WO2024245921 A1 WO 2024245921A1 EP 2024064346 W EP2024064346 W EP 2024064346W WO 2024245921 A1 WO2024245921 A1 WO 2024245921A1
Authority
WO
WIPO (PCT)
Prior art keywords
polysaccharide
water
dispersion
oil
cosmetically acceptable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
PCT/EP2024/064346
Other languages
English (en)
Inventor
Christian Schade
Andreas Bauder
Wolfgang Hecht
Erik BARTHEL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BASF SE
Original Assignee
BASF SE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of WO2024245921A1 publication Critical patent/WO2024245921A1/fr
Anticipated expiration legal-status Critical
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/06—Emulsions
    • A61K8/064—Water-in-oil emulsions, e.g. Water-in-silicone emulsions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/26—Aluminium; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/37—Esters of carboxylic acids
    • A61K8/375—Esters of carboxylic acids the alcohol moiety containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/41—Amines
    • A61K8/416—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/85—Polyesters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
    • A61K8/86—Polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
    • A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/10—Washing or bathing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair

Definitions

  • the present invention relates to a process for making a dispersion of at least one polysaccharide and water in a cosmetically acceptable oil, the process comprising providing a cosmetically acceptable oil, optionally adding at least one additive to the oil, adding at least one polysaccharide to the oil, so that a dispersion of the polysaccharide in the oil is obtained adding water to the dispersion of the at least one polysaccharide in oil, so that a dispersion of the at least one polysaccharide and water in the cosmetically acceptable oil is obtained, wherein the dispersion comprises particles comprising the at least one polysaccharide and water, optionally storing this dispersion for 0.1 to 72 hours, preferably for 0.2 to 48 hours, more preferably for 0.3 to 24 hours, and introducing mechanical energy, preferably by applying shear forces, to the dispersion of the at least one polysaccharide and water in the cosmetically acceptable oil, so that the particle size of the particles comprising the at least one polysaccharide and water is
  • the present invention relates to a method for preparing storage stable inverse emulsions containing an outer water-insoluble oil phase and a dispersed inner phase containing a high concentration of polysaccharides in water.
  • Materials are biodegradable to a great extent and especially useful for cosmetic and pharmaceutical uses.
  • EP 128661 A provides a dispersion of polysaccharide in oil in the presence of surfactants and/or stabilizers.
  • the material is made by dispersing an aqueous solution of the polysaccharide in oil followed by drying the resultant emulsion.
  • the initial polysaccharide solution normally contains at least 80% water, because very concentrated solutions cannot easily be handled and dispersed.
  • EP 137538 describes water-in-oil emulsions of polysaccharides.
  • the polysaccharides are suitably supplied in the form of an aqueous solution with a concentration of up to 10 w.-% [page 2, Z31 ].
  • Polysaccharide powders available in the market are essentially too coarse to be used directly.
  • One approach known in the state of the art is to grind the polysaccharide either dry or suspended in oil, which is usually accompanied by severe reduction in molar mass and thickening potential.
  • Another approach according to the state of the art is to dissolve the polysaccharide in water and to emulsify the polysaccharide solution in the oil phase.
  • emulsions with high concentrations of polysaccharides cannot easily be produced.
  • the viscosity increases rapidly to an extent that makes it difficult to incorporate and hydrate large clusters and lumps of dry, not wetted polymer.
  • the stickiness and viscosity of the resulting sol or gel is high, so that the production of fine emulsions with droplets in the size range below 10 pm is very challenging with conventional dispersing devices like stirred vessels, rotor-stator-dispersing machines, high pressure homogenizers or ultrasound sonotrodes and the like because of the high viscosity ratio between aqueous and oil phase.
  • the problem underlying the present invention is to provide a process for making a dispersion of at least one polysaccharide and water in a cosmetically acceptable oil that overcomes as many of the disadvantages of the processes known in the state of the art. It is especially desirable to provide a process that reduces the amount of water needed, so that not much water has to be removed if a product with low water content shall be made.
  • One embodiment of the present invention is a process for making a dispersion of at least one polysaccharide and water in a cosmetically acceptable oil, the process comprising providing a cosmetically acceptable oil, optionally adding at least one additive to the oil, wherein the additive is selected from the group consisting of a stabilizer and an emulsifier, adding at least one polysaccharide to the oil, so that a dispersion of the polysaccharide in the oil is obtained adding water to the dispersion of the at least one polysaccharide in oil, so that a dispersion of the at least one polysaccharide and water in the cosmetically acceptable oil is obtained, wherein the dispersion comprises particles comprising the at least one polysaccharide and water, optionally storing this dispersion for 0.1 to 72 hours, preferably for 0.2 to 48 hours, more preferably for 0.3 to 30 hours, more preferably 0.5 to 24 hours, more preferably 1 to 24 hours, more preferably 2 to 24 hours, more preferably 2.5 to 24 hours, wherein
  • a storing time of 0.1 hour i. e. 6 minutes
  • Another embodiment of the present invention is the use of a dispersion obtainable by the process according to the present invention making a cosmetic composition.
  • the polysaccharide according to the present invention can be any polysaccharide that is either soluble in water, meaning at least 1 g polysaccharide are soluble in 99 g water at 20 °C, or that is significantly swellable in water, meaning at least 10 g water can be taken up by 90 g polysaccharide at 20°C.
  • Polysaccharides that are neither soluble in water nor swellable in water, e. g. cellulose or chitin, are not polysaccharides according to the present invention.
  • the polysaccharide according to the present invention can be selected from the group consisting of curdlan, sclerotium gum, paenan, guar gum, konjac gum, cassia gum, locust bean gum, tara gum, ceratonia siliqua gum, xanthan gum, dehydroxanthan gum, shizophyllan, scleroglucane, hydrasenyl glucan, welan gum, pullulan, phingane, welan gum, gellan gum, diutan gum, dextran, pektin, cordia gum, acacia gum, karaya gum, traganth gum, heparin, levan, fructan, ghatti gum, succinoglycan, galactoglucan, alginate, carrageenan, fucoidane, ulvan, laminarin, agarose, xyloglucan, cellulose acetate having a degree of substitution of 0.5 - 2, methylcellulose, nitro
  • the polysaccharide according to the present invention may be modified by alkoxylation, especially with hydroxyethyl or hydroxypropyl groups, alkylation, quartenization, conversion with an epoxyalkylammonium salt, oxidation, carboxymethylation, nitration, sufitation, sulfation or phosphation. These modifications may be present alone or together, as in hydroxypropylstarch phosphate. In many cases, otherwise sparingly soluble or swellable polysaccharides may be converted to water dispersible materials by any of these modifications.
  • the polysaccharide according to the present invention can be selected from the group consisting of carrageenan, xanthan gum, gellan gum, and combinations thereof.
  • the at least one cosmetically acceptable oil is selected from the at least one cosmetically acceptable oil
  • the term “cosmetically acceptable oil” or, synonymously, “emollient” is understood to mean substances that make the skin soft and supple, especially by supplying the skin with lipids or reducing evaporation or increasing the moisture content of the skin.
  • Suitable emollients are substances from the group of the oils, fats, waxes, hydrocarbons and/or organosilicon compounds that are liquid at room temperature or have a melting point ⁇ 70°C.
  • Emollients present may be oils, fats and/or waxes, for example from the group formed by esters, wax esters, waxes, triglycerides or partial glycerides, natural vegetable oils or fats, hydrocarbons, organosilicon compounds, guerbet alcohols, mono-/dialkylethers, mono-/dialkyl carbonates, and mixtures thereof.
  • esters that may be present include, but are not limited to, those of linear fatty acids with linear or branched fatty alcohols, esters of linear fatty alcohols with linear or branched carboxylic acids, esters of alkyl hydroxycarboxylic acids with linear or branched fatty alcohols, esters of linear or branched fatty acids with polyhydric alcohols such as diols or trimer triol, wax esters, triglycerides or partial glycerides (called mono-/di-/triglyceride esters), esters of fatty alcohols and/or guerbet alcohols with aromatic carboxylic acids, esters of dicarboxylic acids with linear or branched alcohols, natural vegetable oils or fats and mixtures thereof.
  • Suitable examples from the group of esters of linear C6-C22 fatty acids with linear or branched C6-C22 fatty alcohols or esters of branched C6-C22 carboxylic acids with linear or branched C6-C22 fatty alcohols are myristyl myristate (commercially available as Cetiol® MM), myristyl isostearate, myristyl oleate, myristyl erucate, cetyl isostearate, cetyl oleate, cetyl erucate, stearyl myristate, stearyl isostearate, stearyl oleate, stearyl erucate, isostearyl myristate, isostearyl palmitate, isostearyl stearate, isostearyl isostearate, isostearyl oleate, isopropyl myristate, isopropyl palmitate, oleyl myristate,
  • esters of alkyl hydroxy carboxylic acids with linear or branched C6-C22 fatty alcohols preferably esters of lactic acid such as lauryl lactate.
  • esters of dicarboxylic acids and linear or branched alcohols preferably esters of malic acid, adipic acid and/or sebacic acid, such as dibutyl adipate, dioctyl malate and/or diisopropyl sebacate.
  • esters of linear and/or branched fatty acids with polyhydric alcohols such as propylene glycol, dimer diol or trimer triol
  • polyhydric alcohols such as propylene glycol, dimer diol or trimer triol
  • propylene glycol dicaprylate/dicaprate commercially available as Myritol® PGDC
  • triglycerides based on C6-C10 fatty acids liquid monoglycerides, diglycerides or mono-/di-/triglyceride mixtures based on C6-C18 fatty acids (commercially available as Myritol® 331 , Myritol® 312, Myritol® 318)
  • esters of C6-C22 fatty alcohols and/or Guerbet alcohols with aromatic carboxylic acids especially benzoic acid, esters of benzoic acid with linear and/or branched C6-C22 alcohols (e.g. commercially available as Finsolv® TN, Cetiol®
  • vegetable, fats and oils are groundnut oil, soybean oil, jojoba oil, rapeseed oil, hemp seed oil, avocado oil, argan oil, castor oil, sunflower oil, palm oil, palm kernel oil, linseed oil, almond oil, wheat germ oil, macadamia nut oil, olive oil, sesame oil, cocoa butter and shea butter, for example commercially available as Cegesoft® PFO, Cegesoft® PS 6, Cegesoft® SBE, Cegesoft® SH, Cegesoft® VP or Cetiol® SB 45.
  • emollient are, for example, natural vegetable waxes such as fruit waxes (for example orange waxes) and animal waxes such as wool wax.
  • emollients are C12-C15 fatty alcohols that are usually obtained from natural fats, oils and waxes, such as lauryl alcohol, myristyl alcohol or 1 -pentadecanol.
  • organosilicon compounds which are frequently referred to simply as silicones. They may take the form of cyclic, branched or linear silicones. Silicones are high molecular weight synthetic polymeric compounds in which silicon atoms are joined via oxygen atoms in a chain-like and/or grid-like manner and the remaining valences of silicon are satisfied by hydrocarbon radicals (usually methyl, more rarely ethyl, propyl, phenyl groups etc.). Systematically, the silicones are referred to as polyorganosiloxanes.
  • Advantageous polyorganosiloxanes are, for example, the methyl-substituted polyorganosiloxanes. They are also referred to as Polydimethylsiloxane (PDMS) or Dimethicone (INCI). Dimethicones come in various chain lengths and with various molecular weights. They are available, for example, under the Abil® 350 trade name from Evonik or Xiameter PMX-200 Silicone Fluid trade name from Dow Chemicals.
  • PDMS Polydimethylsiloxane
  • ICI Dimethicone
  • Dimethicones come in various chain lengths and with various molecular weights. They are available, for example, under the Abil® 350 trade name from Evonik or Xiameter PMX-200 Silicone Fluid trade name from Dow Chemicals.
  • phenylmethylpolysiloxane (INCI: Phenyl Dimethicone, Phenyl Trimethicone), cyclic silicones (e.g. decamethylcyclopentasiloxane or dodecamethylcyclopentasiloxane), which are also referred to in accordance with INCI as cyclomethicone, aminomodified silicones (INCI: Amodimethicone) and silicone waxes, e.g.
  • polysiloxane-polyalkylene copolymers (INCI: Stearyl Dimethicone and Cetyl Dimethicone) and dialkoxydimethylpolysiloxanes (Stearoxy Dimethicone and Behenoxy Stearyl Dimethicone), which are available as various Abil wax grades from Evonik. Silicones which are particularly preferred are dimethicone, amodimethicone and cyclomethicone.
  • emollients are mono- and/or dialkyl carbonates of linear or branched C6-C22 fatty alcohols, such as dicaprylyl carbonate (commercially available as Cetiol® CC) or dipropylheptyl carbonate (commercially available as Cetiol® 4AII), Guerbet carbonates based on fatty alcohols having 6 to 18, preferably 8 to 10, carbon atoms, linear or branched, symmetrical or asymmetrical dialkyl ethers having 6 to 22 carbon atoms per alkyl group, for example dicaprylyl ether (commercially available as Cetiol® OE).
  • dicaprylyl carbonate commercially available as Cetiol® CC
  • dipropylheptyl carbonate commercially available as Cetiol® 4AII
  • emollients are hydrocarbons such as mineral oils, paraffinum liquidum, undecane/tridecane (commercially available as Cetiol® Ultimate), hydrogenated polyisobutene (Luvitol® Lite), substituted cyclohexanes, isoparaffins or paraffins as well as C9- C12 alkanes.
  • Suitable Guerbet alcohols are those based on fatty alcohols having 6 to 18, preferably 8 to 10, carbon atoms (commercially available as Eutanol® G, Eutanol® G 16).
  • Particularly preferred emollients according to the present invention include, but are not limited to, symmetrical or asymmetrical dialkyl ethers having 6 to 22 carbon atoms per alkyl group, for example dicaprylyl ether, hydrogenated glycerides, for example hydrogenated vegetable glycerides, mono glycerides, such as glyceryl oleate, liquid mono-/di-/triglyceride mixtures based on C6-C18 fatty acids, and esters of linear C6-C22 fatty acids with isopropanol or linear or branched C6-C22 fatty alcohols, for example isopropyl palmitate, ethylhexyl stearate, coco- caprylate/caprate, and combinations thereof.
  • Particularly preferred emollients according to the present invention include, but are not limited to, coco-glycerides and caprylic/capric triglycerides.
  • the dispersion further comprises at least one emulsifier.
  • emulsifier is understood to mean a substance that stabilizes an emulsion by reducing the oil-water interface tension and that has a molar mass of not more than 6000 g/mol.
  • the at least one emulsifier is an oil-soluble W/O emulsifier.
  • the at least one emulsifier can have an HLB-value of 3 to 8.
  • the at least one emulsifier can be non-ionic.
  • it is miscible with the at least one cosmetically acceptable oil.
  • it is biodegradable.
  • the emulsifier according to the present invention can be a polyethylene glycol-derivative of a fatty alcohol, it can be a polypropylene glycol-derivative of a fatty alcohol, it can be a fatty acid ester of a polyol, e. g. sorbitol, glycerol, polyglycerol, a sugar like sucrose or pentaerythritol, polyethylene glycol, polypropylene glycol, a copolymer of ethylene glycol and propylene glycol, it can be an alkyl polyglycoside.
  • a polyol e. g. sorbitol, glycerol, polyglycerol, a sugar like sucrose or pentaerythritol
  • polyethylene glycol, polypropylene glycol, a copolymer of ethylene glycol and propylene glycol it can be an alkyl polyglycoside.
  • the emulsifier according to the present invention can have a hydrophobic chain having 12 to 30 C-atoms.
  • This hydrophobic chain can be a fatty acid moiety or a fatty alcohol moiety, it can be an oligomeric fatty acid moiety, e. g. resulting from a co-condensation of hydroxyalkyl compounds like hydroxy stearic acid.
  • the emulsifier according to the present invention can be selected from the group consisting of PEG-30 Dipolyhydroxystearate, Polyglyceryl-2 Dipolyhydroxystearate, Polyglyceryl-3 Caprate, Polyglyceryl-3 Diisostearate, Polyglyceryl-3 Distearate, PEG-30 Dipolyhydroxystearate, Polyglyceryl-3 Polyricinoleate, Sorbitan-monooleate, Sorbitan-monostearate, Sorbitan- trioleate or Sorbitan-tristearate.
  • the dispersion further comprises at least one stabilizer.
  • stabilizer is understood to mean polymers or inorganic materials that stabilize an emulsion.
  • the polymers have an average molar mass Mw of more than 1000 g/mol, preferably more than 6000 g/mol, more preferably more than 10000 g/mol.
  • the at least one stabilizer according to the present invention can be a hydrophobic polymer that has polar groups, preferably non-ionic polar groups.
  • the at least one stabilizer according to the present invention can be selected from the group consisting of a copolymer of stearylmethacrylate, methylmethacrylate and methacrylic acid, a copolymer of stearylmethacrylate and methacrylic acid and a block copolymer in which a central poly-1 , 2-propylene glycol group is flanked by two polyethylene glycol groups.
  • the at least one stabilizer according to the present invention can be a polymer having an average molar mass Mw of more than 6000 g/mol, preferably more than 10000 g/mol that stabilizes an emulsion.
  • the stabilizer preferentially is an amphiphilic compound.
  • the stabilizer preferably has a water-solubility of less than 5 w.-% at room temperature.
  • the stabilizer may impart an additional steric stabilization to the dispersion according to the present invention.
  • the stabilizer is preferentially soluble in the emollient or forms stable colloidal dispersions in the emollient.
  • stabilizers are SMA/MAA copolymers, PEG/PPO block copolymers, and the like.
  • the stabilizer is composed of emollient-dispersible particles with an affinity to polar surfaces.
  • Such particles may be inorganic or organic.
  • inorganic particles are bentonites and hectorites which have been loaded with hydrophobic components, an example being Stearylalkonium Hectorite.
  • particulate organic materials are compounds, which are partly insoluble in the emollient used. Examples are hydrophobically modified polysaccharides, e. g. ethyl cellulose.
  • the average particle size of the dispersed particles dso is equal to or less than 25 pm, preferably equal or less than 10 pm, wherein dso is determined by Fraunhofer diffraction measurements carried out with the dispersion.
  • Fraunhofer diffraction measurements carried out with the dispersion is a laser diffraction method. It is carried out as follows. A Mastersizer 3000 (obtainable from Malvern Pananalytical) with a Hydro SV unit installed is used for the measurements. A sample of the dispersion is diluted with the cosmetically acceptable oil of the dispersion. If the dispersion comprises further components apart from the components listed in claim 1 , then the concentration of these further components is kept constant during the dilution by adding corresponding amounts of these further components. Before each measurement, background acquisition measurements are done with a blank sample (comprising the cosmetically acceptable oil and the further components, if any).
  • the pre-diluted dispersion is then added dropwise to the blank sample, without removing the measurement cell from the Mastersizer 3000, upon continuous stirring via an installed stirrer at a rate of 500 - 1000 rpm.
  • the prediluted dispersion is added until an obscuration level of 5-15 % is reached.
  • Data analysis is then performed with the Mastersizer 3000 software using the Fraunhofer scattering model.
  • compositions relate to all compositions known to the person skilled in the art which are exclusively or primarily intended to be used externally on the human body or in its oral cavity for cleaning, care, protection, maintaining a good condition, perfuming, changing the appearance or for the purposes of influencing body odor.
  • Said compositions include formulations for body care, face care, skin care, hand care and hair care as well as decorative cosmetics e. g. body milks, creams, lotions, aftershave lotions, products for eliminating body odor such as deodorants and antiperspirants, make-up removers, conditioners, and styling products.
  • compositions of the present invention can be any of the above. In an embodiment of the present invention they are selected from shower gels, hair shampoos, foam and showers baths, skin care creams, in particular hand care creams, and body lotions. In various embodiments, the composition is a rinse off composition. This includes, without limitation, shower gels, shampoos, hair conditioners, foam baths and the like.
  • the one or more further cosmetically acceptable ingredients can be any cosmetically acceptable ingredient.
  • cosmetically acceptable ingredients E. g. the database Cosing on the homepage of the European Commission discloses cosmetic ingredients and the International Cosmetic Ingredient Dictionary and Handbook, edited by the Personal Care Products Council (PCPC) discloses cosmetic ingredients.
  • PCPC Personal Care Products Council
  • compositions comprise at least one surfactant.
  • Surfactants are amphiphilic substances which can dissolve organic, nonpolar substances in water. They cause, as a result of their specific molecular structure with at least one hydrophilic and a hydrophobic molecular moiety, a lowering of the surface tension of the water, the wetting of the skin, the facilitation of soil removal and dissolution, easy rinse-off and - if desired - foam regulation. Surfactants are typically understood to mean surface-active substances which have an HLB value of greater than 20.
  • Suitable surfactants include all those generally used in the field of cosmetic and personal care compositions and known to those skilled in the art.
  • the surfactants used may be anionic, nonionic, cationic, and/or amphoteric or zwitterionic surfactants.
  • surfactant-containing compositions for example shower gels, foam baths, shampoos etc. at least one anionic surfactant is preferably present.
  • the anionic surfactant can be combined with another type of surfactant, typically with the exception of cationic surfactants, in particular nonionic or zwitterionic/ampholytic surfactants.
  • more than one surfactant of any type may be included, for example 2, 3, 4, 5 or more different (types of) surfactants.
  • Alkyl (ether) sulfates and “fatty alcohol (ether) sulfates”, as used herein, relate to the well- known class of anionic surfactants of sulfated fatty alcohols and sulfated fatty alcohol ethers, in particular the ethoxylated, propoxylated or mixed ethoxylated/propoxylated ethers of fatty alcohols.
  • surfactants thus include sodium lauryl ether sulfate (SLES) and sodium lauryl sulfate (SLS or SDS). As disclosed herein below, it is preferred that these are only used in low amounts or the compositions are free of such surfactants.
  • Typical examples of usable nonionic surfactants are fatty alcohol polyglycol ethers, alkylphenol polyglycol ethers, fatty acid polyglycol esters, fatty acid amide polyglycol ethers, fatty amine polyglycol ethers, alkoxylated triglycerides, mixed ethers and mixed formals, optionally partially oxidized alk(en)yl (poly)glycosides and glucuronic acid derivatives, fatty acid N- alkylglucamides, protein hydrolysates (especially wheat-based vegetable products), polyol fatty acid esters, sugar esters, sorbitan esters, polysorbates and amine oxides. If the nonionic surfactants contain polyglycol ether chains, they may have a conventional homolog distribution, but preferably have a narrow homolog distribution.
  • Zwitterionic surfactants refer to those surface-active compounds which bear at least one quaternary ammonium group and at least one -COO(-) or -SO3(-) group in the molecule.
  • Particularly suitable zwitterionic surfactants are the betaines, such as the N-alkyl-N,N- dimethylammonium glycinates, for example cocoalkyl dimethylammonium glycinate, N- acylaminopropyl-N,N-dimethylammonium glycinates, for example cocoacylamino- propyldimethylammonium glycinate, and 2-alkyl-3-carboxymethyl-3-hydroxyethylimidazoline having in each case 8 to 18 carbon atoms in the alkyl or acyl group, and also cocoacylaminoethyl hydroxyethylcarboxymethyl glycinate.
  • ampholytic surfactants are understood to mean those surface-active compounds which, apart from a C8-C18-alkyl or acyl group in the molecule, contain at least one free amino group and at least one -COOH or -SO3H group and are capable of forming internal salts.
  • ampholytic surfactants are N-alkylglycines, N-alkylpropionic acids, N-alkylaminobutyric acids, N- alkyliminodipropionic acids, N-hydroxyethyl-N-alkylamidopropyhglycines, N-alkyltaurines, N- alkylsarcosines, 2-alkylaminopropionic acids and alkylaminoacetic acids having in each case about 8 to 18 carbon atoms in the alkyl group.
  • Particularly preferred ampholytic surfactants are N-cocoalkylaminopropionate, cocoacylaminoethyl-aminopropionate and C12-18- acylsarcosine.
  • amphoteric or zwitterionic surfactants are alkylbetaines, alkylamidobetaines, aminopropionates, aminoglycinates, imidazolinium betaines and sulfobetaines.
  • anionic surfactants are soaps, alkylbenzenesulfonates, alkanesulfonates, olefin-sulfonates, alkyl ether sulfonates, glycerol ether sulfonates, a-methyl ester sulfonates, sulfo fatty acids, mono- and dialkyl sulfosuccinates, mono- and dialkyl sulfosuccinamates, sulfotriglycerides, amide soaps, ethercarboxylic acids and salts thereof, fatty acid isethionates, fatty acid sarcosinates, fatty acid taurides, N-acylamino acids, for example acyl lactylates, acyl tartrates, acyl glutamates and acyl aspartates, alkyl oligoglucoside sulfates, protein fatty acid condensates (especially vegetable products based on wheat)
  • compositions may contain alkyl (ether) sulfates, including fatty alcohol (ether) sulfates, it is preferred that these are only present in low amounts of less than 2 wt.-%, such as 1 wt.-% or lower, or more preferred completely absent.
  • the rinse-off compositions disclosed herein are preferably free of such alkyl (ether)sulfates.
  • Cationic surfactants which can be used are especially quaternary ammonium compounds.
  • ammonium halides especially chlorides and bromides, such as alkyltrimethylammonium chlorides, dialkyldimethylammonium chlorides and trialkylmethylammonium chlorides, e.g. cetyltrimethylammonium chloride, stearyltrimethylammonium chloride, distearyldimethylammonium chloride, lauryldimethylammonium chloride, lauryldimethylbenzylammonium chloride and tricetylmethylammonium chloride.
  • the very readily biodegradable quaternary ester compounds for example the dialkylammonium methosulfates and methylhydroxyalkyldialkyloxyalkylammonium methosulfates sold under the trade name Stepantex® and the corresponding products of the Dehyquart® series can also be used as cationic surfactants.
  • ester quats are generally understood to mean quaternized fatty acid triethanolamine ester salts. These are known substances which are prepared by the relevant methods of organic chemistry.
  • Further cationic surfactants which can be used in accordance with the invention are the quaternized protein hydrolysates.
  • Typical examples of particularly suitable mild, i.e. particularly skin-friendly, surfactants are mono- and/or dialkyl sulfosuccinates, fatty acid isethionates, fatty acid sarcosinates, fatty acid taurides, fatty acid glutamates, a-olefinsulfonates, ether carboxylic acids, 2-sulfonated fatty acids, alkyl (poly)glycosides/-glucosides and/or mixtures thereof with alkyl oligoglucoside carboxylates, fatty acid glucamides, alkylamidobetaines, amphoacetals, protein hydrolysates, and/or protein fatty acid condensates, the latter preferably based on wheat proteins or salts thereof.
  • These surfactants are preferred surfactants to be used in the compositions of the invention. In the compositions of the invention, these may be used individually or in combination.
  • Preferred surfactants are also generally those that are obtainable from renewable raw materials and are readily biodegradable.
  • Alk(en)yl (poly)glycosides may be compounds of formula (I),
  • APG as used herein, thus is intended to cover both alkyl and alkenyl (poly)glycosides.
  • APGs of the form claimed here can be obtained by the relevant methods of preparative organic chemistry.
  • the APGs can be derived from aldoses or ketoses with 5 or 6 carbon atoms. While various sugar units may be used, in various embodiments, the sugar units of the APGs are derived from glucose.
  • the degree of oligomerization of the APGs is between 1 and 10 and preferably between 1 and 6.
  • p in an individual APG molecule must always be an integer and here in particular assumes the values in the range from 1 to 6, the value p for an APG which is a mixture of different APG molecules, which differ in their individual p values, is an analytically determined calculated parameter which in most cases is a fraction.
  • APGs are used with an average degree of oligomerization p in the range from 1.1 to 3.0 or from 1.1 to 1 .8 or from 1.2 to 1 .7.
  • the average degree of oligomerization here is to be understood in the sense of how it is defined in the monograph K. Hill, W. von Rybinski, G. Stoll “Alkyl Polyglycosides. Technology, Properties and Applications” (VCH-Verlagsgesellschft, 1996) in the section “Degree of polymerization” (compare pages 11-12 of the book): there it reads “The average number of glycose units linked to an alcohol group is described as the (average) degree of polymerization (DP).” In explanatory figure 2, which describes a typical distribution of dodecyl glycoside oligomers of an AOPG with a degree of DP of 1.3, the average degree of DP is also described by a corresponding mathematical formula.
  • the radical R 1 is preferably derived from primary alcohols with 4 to 12 carbon atoms and preferably 8 to 10 carbon atoms.
  • suitable radicals R 1 are butyl, hexyl, octyl, decyl, undecyl, dodecyl and myristyl.
  • APGs which are derived from glucose and in which the radical R 1 is a saturated alkyl radical with 8 to 12 carbon atoms and which have an average degree of oligomerization in the range from 1.1 to 3 and in particular in the range from 1.2 to 1.8 and particularly preferably in the range from 1.2 to 1.7.
  • These APGs can for example be prepared by reacting a sugar, in particular glucose, under acid catalysis with a fatty alcohol mixture, the fatty acid mixture used preferably being a forerunning produced during the distillative separation of technical-grade Cs-is-coconut fatty alcohol, which comprises predominantly octanol-1 and decanol-1 and also small amounts of dodecanol-1.
  • Suitable 2-sulfonated fatty acids include, without limitation, 2-sulfolaurate and salts thereof, in particular disodium 2-sulfolaurate.
  • the compositions of the invention include at least one surfactant.
  • the at least one surfactant may be present in amounts of from 1 to 30 wt.-%, preferably 2 to 25 wt.-% or 5 to 25 wt.-% or 8 to 30 wt.-% or 10 to 25 wt.-% or 15 to 25 wt.-%, relative to the total weight of the composition.
  • the at least one surfactant is present in amounts of 5 to 20 or 10 to 15 wt.-%.
  • Such surfactant-containing compositions may, in various embodiments, be the rinse-off compositions described herein.
  • At least one anionic surfactant is preferably present, preferably in combination with at least one nonionic or zwitterionic surfactant.
  • the at least one anionic surfactant and the at least one nonionic surfactant may be selected from the surfactants indicated as being preferred above.
  • the anionic surfactant may be a 2-sulfonated fatty acid, such as 2-sulfolaurate, and the nonionic surfactant may be an APG.
  • the anionic surfactant may alternative be a sulfosuccinate or fatty acid glutamate and the nonionic/zwitterionic surfactant may be an alkylamidobetaine.
  • compositions of the invention can comprise a series of further auxiliaries and additives, such as, for example, preservatives, dyes, coloring agents, pigments, fragrances, humectants, emulsifiers, opacifiers, pearlescent agents, buffering and pH adjustment agents, conditioning agents and antioxidants.
  • auxiliaries and additives such as, for example, preservatives, dyes, coloring agents, pigments, fragrances, humectants, emulsifiers, opacifiers, pearlescent agents, buffering and pH adjustment agents, conditioning agents and antioxidants.
  • Suitable compounds are commercially available and well-known to those skilled in the art.
  • Suitable humectants include sorbitol, glycerol, propylene glycol, xylitol, liquid polyethylene glycol and mixtures thereof. If used in the compositions, the weight ratio of water to humectant is preferably at least 10:1 and up to 30:1 , with the total amount of humectant ranging from 2 to 8 wt.-%, relative to the total weight of the composition, for example 3 to 7 or 4 to 6 wt.-%.
  • the compositions may comprise polyquaternium-10 (quaternized hydroxyethyl cellulose) as a conditioning agent.
  • the compositions are preferably rinse-off formulations, such as shower gels, shampoos and bath foams.
  • compositions of the invention comprise cationic guar gum, preferably guar hydroxypropyltrimonium salt, typically the chloride salt.
  • Guar gum is a galactomannan polysaccharide extracted from guar beans that is known for its thickening and stabilizing properties useful in food applications.
  • Cationic guar (gum) is obtained by quaternization of guar gum, the most common cationic guar being guar hydroxypropyltrimonium. It is typically used in form of its salt, in particular the chloride salt.
  • compositions of the invention may optionally contain cationic guar in an amount of 0.01 to 1.0 wt.-%, preferably 0.2 to 0.6 wt.-%, relative to the total weight of the composition.
  • the compositions are preferably rinse-off formulations, such as shower gels, shampoos and bath foams.
  • the compositions of the invention are free of (poly)acrylate thickeners or, preferably, generally free of polyacrylates, including acrylate copolymers.
  • the compositions of the invention are generally free of synthetic polymeric thickeners.
  • the compositions do not contain any thickeners or rheology modifying agents other than xanthan gum and hydroxypropyl starch (phosphate).
  • thickeners and “rheology modifiers” preferably refer to compounds only added for the purpose to increase or adjust viscosity and rheology and which do not function as other components of the composition, such as surfactants, emollients or any of the other auxiliary substances listed above.
  • compositions of the invention are also free of organic UV filters selected from (hydroxy)benzophenones, ethylhexyl triazone, ethylhexyl methoxycinnamate, octocrylene, and ethylhexyl salicylate.
  • the compositions of the invention are also free of organic UV filters selected from (hydroxy)benzophenones, triazines, triazones, ethylhexyl methoxycinnamate, octocrylene, homosalate and ethylhexyl salicylate.
  • the personal care compositions of the invention are not sunscreens.
  • compositions of the invention are also free of fluorinated organic compounds, more preferably free of halogenated organic compounds. This relates to organic compounds that have fluorine or any other halogen bonded by a covalent bond, but does not extend to halogen salts (halides).
  • compositions of the invention are preferably also free of alkyl (ether) sulfate surfactants or contain those only in small amounts of less than 2 wt.-%, preferably 1 wt.-% or less.
  • compositions of the invention are preferably also free of oxidizing agents, such as those used in hair dyes, in particular hydrogen peroxide or hydrogen peroxide generating compounds.
  • oxidizing agents such as those used in hair dyes, in particular hydrogen peroxide or hydrogen peroxide generating compounds.
  • the compositions of the invention are not hair dyes.
  • compositions of the present invention may be based, in various embodiments, predominantly on components derived from renewable raw materials. In various embodiments this may mean that more than 50 wt.-%, preferably more than 60, more than 70, more than 80 or more than 90 wt.-% of the components of the composition other than water are derived from renewable raw materials. It may be preferred that all non-water components are derived from renewable raw materials. Said renewable materials include, but are not limited to, plant-based materials. It may be preferred that less than 10 wt.-%, more preferably none of the non-water components of the compositions are derived from fossil sources or fossil fuels.
  • the compositions of the present invention may be based, in various embodiments, predominantly on components that are biodegradable.
  • this may mean that more than 50 wt.-%, preferably more than 60, more than 70, more than 80 or more than 90 wt.-% of the components of the composition besides water are biodegradable. It may be preferred that all non-water components are biodegradable.
  • the biodegradability is preferably determined according to OECD 301 F or OECD 302 C (MITI-II test), with ..biodegradable" components preferably having a biodegradability of at least 40%, preferably 60% determined according to OECD 301 F and/or at least 20%, preferably at least 40% according to OECD 302 C.
  • compositions of the invention preferably have a pH at 20°C in the range of 3.5 to 7.0, preferably 4.0 to 6.5. more preferably 4.5 to 6.5, for example 4.8 to 5.2 or 6.0. to 6.2.
  • the pH value may be determined directly or, preferably, as a 1% solution or dispersion in deionized water.
  • the viscosity of the compositions is preferably at least 2.000 mPa.s (determined at 20°C in a Brookfield DV-I+, Spindle 4, 10 rpm) and may be as high as 50.000 mPa.s (determined at 20°C in a Brookfield DV-I+, Spindle TC, Helipath, 10 rpm).
  • Introducing mechanical energy can inter alia be achieved by applying shear forces or by applying elongational forces or by applying inertial forces or by applying cavitation.
  • Stirring can be done by using dispersing equipment like stirrers, dissolver disks or rotor-stator- machines.
  • the amount of polysaccharide used per 100 g of cosmetically acceptable oil used is at least 10 g or more, preferably at least 15 g or more, more preferably at least 25 g or more.
  • polysaccharide powder is dispersed without water under shear in a previously prepared solution of a cosmetically acceptable oil phase with stabilizing additives.
  • dispersing equipment like stirrers, dissolver disks or rotor-stator-machines can be used. Subsequently, water is added gradually under strong agitation allowing it to diffuse to the individual hydrophilic polysaccharide particles and to hydrate them.
  • the dispersion can optionally be left for a certain time to allow for a further swelling of the polysaccharide particles.
  • the agitation of the inverse emulsion system is continued during this step.
  • the swollen gel particles are dispersed in a second dispersing step, again using dispersing technologies like stirred vessels, rotor-stator-dispersing machines, high pressure homogenizers or ultrasound sonotrodes and the like, to produce a finely dispersed water-in-oil emulsion.
  • the water-swollen, softened state of the polysaccharide seems to help to limit polymer degradation as observed in milling approaches in absence of water.
  • the dispersion obtained by the process according to the present invention can be used as such; alternatively, water can be optionally removed, e. g. by applying vacuum.
  • % means % by weight unless a different definition is given.
  • Xanthan gum was milled in Emollient 1 in a ball mill for 30 minutes. A sedimenting suspension was obtained. The thickening power of the xanthan gum was massively reduced: Prior to milling: Gel 1 weight-% in water: 4000 mPas (Brookfield, RT, 20 rpm, Sp.6)
  • This comparative example shows that it was not possible to obtain a stable suspension of small xanthan gum particles in Emollient 1 by milling.
  • the dispersing step in the absence of water led to the deterioration of the gel properties.
  • An emulsion was prepared in the following manner:
  • Dispersion Step 1 To 200 g of Emollient 1 were added 13.8 g of Additive 1 and 28 g of Additive 4 solution (20 w.-% in Emollient 1) under gentle stirring until a clear solution was obtained. Using a dissolver disc with a diameter of 40 mm, 45 g of kappa-Carrageenan were added within 2 minutes time. Under external cooling with ice, 120 g of demineralized water were added slowly while dispersing at 6000 rpm for 4 minutes; stirring was continued for another 10 minutes. The emulsion was kept at room temperature for 24 h.
  • Dispersion Step 2 After the maturation time, the emulsion was dispersed using the dissolver at 6000 rpm and a batch rotor-stator shear unit with a rotor tip speed of 24 meters per second (m/s) at the same time (4 cycles, each 2,5 minutes). The temperature was controlled not to exceed 40°C. A whitish, storage-stable emulsion with increased viscosity but sufficient flowability was obtained. According to light-microscopic pictures, the Carrageenan-water droplets obtained in the Emollient 1 were smaller than 10 pm in diameter.
  • Example 2 In a similar manner as in Example 2 the following compositions have been prepared using gellan gum as polysaccharide. The resulting emulsions were smooth and stable.
  • the emulsion was poured into water so that a system containing 0.5 w.-% of the polysaccharide was obtained. The viscosity of the mixture was subsequently determined.
  • a suspension of 14,5 g of gellan gum in 62 g of Emollient 1 and 2.1 g of Additive 1 was premixed and filled into a ball mill. With start of the milling, 21.4 g of water were added over a period of 5 mins and the milling continued for 30 mins. We obtained a smooth and stable emulsion.
  • the emulsion was poured into water in a manner that a system containing 1 w.-% of the polysaccharide was obtained.
  • the viscosity of the mixture was subsequently determined to be 28000 mPas. Examples 5 - 8
  • Xanthan emulsions have been prepared. We obtained very smooth and flowable emulsions, which were storage stable. After pouring into water, they readily developed the viscosity expected from their respective Xanthan content.
  • the particle size of these emulsions was determined by Fraunhofer Laser diffraction using a Malvern Mastersizer 3000.
  • the emulsions were diluted with Myritol® 331 solvent prior to the measurement.
  • An emulsion was prepared in the following manner:
  • Dispersion Step 1 To 182 g of Emollient 2 were added 65 g of Additive 1 and 130 g of Additive 4 solution (20 w.-% in Emollient 1) under gentle stirring until a clear solution was obtained. Using a dissolver disc with a diameter of 40 mm, 120 g of Xanthan Gum were added within 2 minutes time. Under external cooling with ice, 300 g of demineralized water were added slowly while dispersing at 6000 rpm for 4 minutes; stirring was continued for another 10 minutes. The emulsion was kept at room temperature for 24 h.
  • Dispersion Step 2 After the maturation time, the emulsion was dispersed using the dissolver at 6000 rpm and a batch rotor-stator shear unit with a rotor tip speed of 24 meters per second (m/s) at the same time (4 cycles, each 2.5 minutes). The temperature was controlled not to exceed 40°C. We obtained a whitish, storage-stable emulsion with very favourable flowability. According to light-microscopic pictures, the Xanthan-water droplets obtained were smaller than 10 pm in diameter.
  • Example 11 In a similar manner as in Example 9, a stable low viscous emulsion was prepared from 60 g of Xanthan Gum, 150 g of water, 123 g of Emollient 1 , 20 g of Additive 3 and 16 g of Additive 6.
  • Example 11 In a similar manner as in Example 9, a stable low viscous emulsion was prepared from 60 g of Xanthan Gum, 150 g of water, 123 g of Emollient 1 , 20 g of Additive 3 and 16 g of Additive 6.
  • Example 11 Example 11
  • An emulsion was prepared in the following manner:
  • Dispersion Step 1 To 296 g of Emollient 1 were added 65 g of Additive 1 and 130 g of additive 4 solution (20 w.-% in Emollient 1) under gentle stirring until a clear solution was obtained. Using a dissolver disc with a diameter of 40 mm and a rotational speed of 6000 rpm, 195 g of Xanthan Gum were added within 2 minutes time. Under external cooling with ice, 488 g of demineralized water were added slowly while dispersing at 6000 rpm for 4 minutes; stirring was continued for another 10 minutes. The emulsion was kept at room temperature for 24 h.
  • Dispersion Step 2 After the maturation time, the emulsion was dispersed using an inline rotorstator dispersing machine equipped with a tooth-and-chamber dispersing tool with 47 meters per second (m/s) rotor tip speed and 1 .3 kg/h flow rate. The temperature was controlled not to exceed 40°C. We obtained a whitish, storage-stable emulsion with very favourable flowability. According to light-microscopic pictures, the Xanthan-water droplets obtained were smaller than 10 pm in diameter.
  • An emulsion was prepared in the following manner:
  • Dispersion Step 1 To 273 g of Emollient 1 were added 60 g of Additive 1 and 120 g of Additive 4 solution (20 w.-% in Emollient 1) under gentle stirring until a clear solution was obtained. Using a dissolver disc with a diameter of 40 mm and a rotational speed of 6000 rpm, 180 g of Xanthan Gum were added within 2 minutes time. Under external cooling with ice, 450 g of demineralized water were added slowly while dispersing at 6000 rpm for 4 minutes; stirring was continued for another 10 minutes. The emulsion was kept at room temperature for 24 h.
  • Dispersion Step 2 After the maturation time, the emulsion was dispersed using a two-stage high pressure homogenizer. The emulsion was homogenized in 4 straight passes with a homogenizing pressure of 600 bar in the first and with 60 bar in the second homogenizing stage. The temperature was controlled not to exceed 40°C. A whitish, storage-stable emulsion with very favourable flowability was obtained. According to light-microscopic pictures, the Xanthan-water droplets in the emulsion were smaller than 10 pm in diameter.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Dispersion Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne un processus de fabrication d'une dispersion d'au moins un polysaccharide et d'eau dans une huile cosmétiquement acceptable, le processus consistant à fournir une huile cosmétiquement acceptable, éventuellement à ajouter au moins un additif à l'huile, à ajouter au moins un polysaccharide à l'huile, de sorte qu'une dispersion du polysaccharide dans l'huile est obtenue, à ajouter de l'eau à la dispersion du ou des polysaccharides dans l'huile, de sorte qu'une dispersion du ou des polysaccharides et de l'eau dans l'huile cosmétiquement acceptable est obtenue, la dispersion comprenant des particules comprenant le ou les polysaccharides et l'eau, éventuellement à stocker cette dispersion pendant 0,1 à 72 heures, de préférence pendant 0,2 à 48 heures, de préférence encore pendant 0,3 à 24 heures, et à introduire de l'énergie mécanique, de préférence par application de forces de cisaillement, à la dispersion du ou des polysaccharides et de l'eau dans l'huile cosmétiquement acceptable, de sorte que la taille de particule des particules comprenant le ou les polysaccharides et l'eau est réduite. En outre, la présente invention concerne l'utilisation d'une dispersion pouvant être obtenue par ce processus pour fabriquer une composition cosmétique.
PCT/EP2024/064346 2023-06-01 2024-05-24 Processus de fabrication d'une dispersion Pending WO2024245921A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP23176699.9 2023-06-01
EP23176699 2023-06-01
EP23196892 2023-09-12
EP23196892.6 2023-09-12

Publications (1)

Publication Number Publication Date
WO2024245921A1 true WO2024245921A1 (fr) 2024-12-05

Family

ID=91331085

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/EP2024/064344 Pending WO2024245919A1 (fr) 2023-06-01 2024-05-24 Dispersion comprenant du xanthane traité thermiquement
PCT/EP2024/064346 Pending WO2024245921A1 (fr) 2023-06-01 2024-05-24 Processus de fabrication d'une dispersion

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/EP2024/064344 Pending WO2024245919A1 (fr) 2023-06-01 2024-05-24 Dispersion comprenant du xanthane traité thermiquement

Country Status (1)

Country Link
WO (2) WO2024245919A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0128661A1 (fr) 1983-05-17 1984-12-19 Ciba Specialty Chemicals Water Treatments Limited Suspensions de polymères
EP0137538A2 (fr) 1983-09-09 1985-04-17 Shell Internationale Researchmaatschappij B.V. Compositions de biopolymère et procédés pour leur préparation
DE10361213A1 (de) * 2003-12-24 2005-07-28 Beiersdorf Ag Verfahren zur Quellung oder Lösung von Carrageenan
WO2007091016A1 (fr) * 2006-02-08 2007-08-16 Croda International Plc Systèmes d'émulsification, émulsions et lingettes humides comprenant de telles émulsions
DE60033188T2 (de) * 2000-06-26 2007-12-13 National Starch And Chemical Investment Holding Corp., Wilmington Kosmetisches Mittel enthaltend ein Polysaccharid und ein Organopolysiloxan-Polyoxyalkylen-Copolymer als Emulgatoren
DE102009019550A1 (de) * 2009-04-30 2011-04-07 Optisens Gmbh Konzentrierte, cremige bis feste und trockene Zusammensetzung einer Öl-in-Wasser-Emulsion und Verfahren zu deren Herstellung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4462659B2 (ja) * 1998-07-07 2010-05-12 日清オイリオグループ株式会社 不揮発性有機溶媒含有キサンタンガムおよびその製造方法
US8545828B1 (en) 2003-02-21 2013-10-01 Akzo Nobel N. V. High viscosity heat-treated xanthan gum

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0128661A1 (fr) 1983-05-17 1984-12-19 Ciba Specialty Chemicals Water Treatments Limited Suspensions de polymères
EP0137538A2 (fr) 1983-09-09 1985-04-17 Shell Internationale Researchmaatschappij B.V. Compositions de biopolymère et procédés pour leur préparation
DE60033188T2 (de) * 2000-06-26 2007-12-13 National Starch And Chemical Investment Holding Corp., Wilmington Kosmetisches Mittel enthaltend ein Polysaccharid und ein Organopolysiloxan-Polyoxyalkylen-Copolymer als Emulgatoren
DE10361213A1 (de) * 2003-12-24 2005-07-28 Beiersdorf Ag Verfahren zur Quellung oder Lösung von Carrageenan
WO2007091016A1 (fr) * 2006-02-08 2007-08-16 Croda International Plc Systèmes d'émulsification, émulsions et lingettes humides comprenant de telles émulsions
DE102009019550A1 (de) * 2009-04-30 2011-04-07 Optisens Gmbh Konzentrierte, cremige bis feste und trockene Zusammensetzung einer Öl-in-Wasser-Emulsion und Verfahren zu deren Herstellung

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HELMAR SCHUBERT: "Emulgiertechnik - Grundlagen, Verfahren und Anwendungen", 2005, B. BEHR'S VERLAG GMBH & CO. KG

Also Published As

Publication number Publication date
WO2024245919A1 (fr) 2024-12-05

Similar Documents

Publication Publication Date Title
JP4662637B2 (ja) 乳化システム及び乳剤
JP5048515B2 (ja) コロイド状陽イオン粒子を用いて予め乳化した疎水性の有益助剤を含む洗浄用組成物とその製造方法
JP7044751B2 (ja) 粘液性シリコーンエマルジョン
CN109328054B (zh) 个人清洁组合物
CN101802084A (zh) 包括一种或多种疏水改性的聚丙烯酰胺的组合物以及使用所述组合物的方法
CN102812115A (zh) 包含含有蜡的微乳液的清洁剂的用途
KR101847807B1 (ko) 가교결합된 아미노실록산 중합체의 에멀젼
CA3228529A1 (fr) Composition
US20080242739A1 (en) Mixed hydrophobe polysaccharide as polymeric emulsifier and stabilizer
US9913786B2 (en) Moisturizing composition which may be applied to wet skin in the form of an oil-in-water emulsion; moisturizing care process
JP6377052B2 (ja) 植物レシチンを含む毛髪化粧料組成物
WO2024245921A1 (fr) Processus de fabrication d'une dispersion
KR102756260B1 (ko) 초친수성 양친매성 공중합체를 포함하는 썬스크린 조성물
KR102733162B1 (ko) 자외 방사선-흡수 화합물 및 초친수성 양친매성 공중합체를 함유하는 발포 썬스크린 조성물
EP3027169B1 (fr) Composition de soin personnel moussante comprenant une phase continue huileuse
WO2024184209A1 (fr) Compositions de soins personnels comprenant de la gomme xanthane et de l'amidon hydroxypropylé
WO2021156213A1 (fr) Nanoparticules lipidiques permettant l'administration retardée d'un parfum ayant une solubilité améliorée dans l'eau, leur préparation et utilisation
US20250360067A1 (en) Personal care composition substantially free of alkyl sulfate or alkyl ether sulfate type of surfactants
US20250319009A1 (en) Personal care composition substantially free of alkyl sulfate or alkyl ether sulfate type of surfactants
MXPA00003797A (en) Use of substantially amorphous cellulose nanofibrils associated with a polyhydroxylated organic compound in cosmetic formulations
TW200831523A (en) Saccharide esters and their use as surfactant
KR20150044641A (ko) D상 유화공정을 사용하면서 피부안전성과 보습효과가 우수한 나노유화물을 생성하는 조제공법

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 24729762

Country of ref document: EP

Kind code of ref document: A1