WO2024139717A1 - Electrode patch, manufacturing method therefor, and tumor electric field therapeutic apparatus - Google Patents

Abstract

The present invention provides an electrode patch, a manufacturing method therefor, and a tumor electric field therapeutic apparatus. The electrode patch comprises at least one electrode unit, an adapter board formed by a flexible circuit board, and a backing. Both the electrode unit and the adapter board are partially adhered to the backing. The electrode unit comprises a flexible board substrate having a male seat arranged thereon. The adapter board has at least one female seat arranged thereon. The male seat is inserted into the female seat to enable a detachable, electrical connection between the electrode unit and the adapter board. The electrode patch of the present invention is formed by detachably connecting at least one electrode unit to the adapter board, so that a failed electrode unit on the electrode patch can be detachably replaced or a failed adapter board on the electrode patch can be detachably replaced to reduce the loss of the entire electrode patch and reduce the yield loss of the electrode patch.

Description

Electrode patch, manufacturing method of electrode patch and tumor electric field therapeutic device

This application claims priority to the following patent applications: Chinese Patent Application No. 202211678871.X, filed on December 26, 2022, Chinese Patent Application No. 202223483427.0, filed on December 26, 2022, Chinese Patent Application No. 202211678713.4, filed on December 26, 2022, Chinese Patent Application No. 202223483410.5, filed on December 26, 2022, Chinese Patent Application No. 202211678884.7, filed on December 26, 2022, and Chinese Patent Application No. 202223483419.6, filed on December 26, 2022. The entire contents of the above Chinese patent applications are incorporated by reference into the application herein.

Technical Field

The present application relates to the technical field of medical devices, and in particular to an electrode patch, a method for manufacturing the electrode patch, and a tumor electric field therapy device.

Background technique

At present, the main treatments for tumors include surgery, radiotherapy, chemotherapy, etc., but they all have corresponding disadvantages. For example, radiotherapy and chemotherapy can produce side effects and kill normal cells. Using electric fields to treat tumors is also one of the current research and development frontiers. Tumor electric field therapy uses a special electric field generator to produce a tumor treatment method that interferes with the mitotic process of tumor cells through low-intensity, medium-high frequency, alternating electric fields. Studies have shown that electric field therapy is effective in treating glioblastoma, non-small cell lung cancer, malignant pleural mesothelioma and other diseases. The electric field applied by this treatment method can affect the aggregation of microtubule proteins, prevent spindle formation, inhibit the mitotic process, and induce apoptosis of cancer cells.

The tumor electric field therapy device used to treat tumors mainly includes an electric field generator and an electrode patch electrically connected to the electric field generator. The electrode patches are applied to the human skin in pairs to apply an alternating electric field to the lesions of the human body for alternating electric field therapy. Each electrode patch includes a flexible circuit board, A plurality of ceramic sheets arranged at intervals on a flexible circuit board and a wire electrically connected to the flexible circuit board are disclosed in Chinese invention patent publication No. 11271272 or No. 113164745. The flexible circuit board includes a flexible board substrate, a plurality of conductive traces embedded in the flexible board substrate, and a plurality of conductive pads exposed on the flexible board substrate and electrically connected to the same conductive trace. A plurality of ceramic sheets are arranged on the flexible circuit board by welding with corresponding conductive pads, and then connected in series through a conductive trace electrically connected to all conductive pads. One end of the wire is electrically connected to the flexible circuit board, and the other end is provided with a plug that can be plugged into the electric field generator.

Since the ceramic sheet is a hard material and the flexible circuit board is a flexible material, the mechanical strength of the flexible circuit board of the electrode patch of the above-mentioned tumor electric field therapy device is stronger in the area where multiple ceramic sheets are arranged at intervals than in the area where no ceramic sheets are arranged, which makes it easy for the flexible circuit board to bend at the junction of the area where the ceramic sheets are arranged and the area where the ceramic sheets are not arranged. If the bending is serious, there is also a risk of the conductive traces in the flexible board substrate breaking. The multiple ceramic sheets of the electrode patch are connected in series through the same conductive trace of the flexible circuit board. There is a risk that the electrical signal used for tumor electric field therapy cannot be transmitted to all the ceramic sheets due to the breakage of the conductive trace of the flexible circuit board, resulting in the electrode patch being scrapped as a whole due to unqualified inspection during manufacturing, and cannot be used or reused, resulting in low product manufacturing yield and increased manufacturing costs; resulting in the electrode patch being unable to apply an alternating electric field to the patient's tumor site for tumor electric field therapy when in use.

Therefore, it is indeed necessary to provide an improved electrode patch and tumor electric field therapy device to solve the technical problems existing in the electrode patch of the above-mentioned tumor electric field therapy device.

Summary of the invention

The invention provides an electrode patch capable of preventing the entire electrode patch from being scrapped, a method for manufacturing the electrode patch, and a tumor electric field therapeutic apparatus.

In view of the problems existing in the prior art, the present invention provides an electrode patch which is realized by the following technical solution: an electrode patch for tumor electric field therapy, comprising at least one electrode unit, a transfer board formed by a flexible circuit board and a backing, wherein the electrode unit and the transfer board are partially attached to the backing, the electrode unit comprises a flexible board substrate, the flexible board substrate A male socket is provided on the body, and at least one female socket is provided on the adapter plate. The male socket and the female socket are plugged into each other so that the electrode unit and the adapter plate are detachably electrically connected.

Furthermore, each of the electrode units comprises a support plate and a dielectric element respectively arranged on both sides of the flexible board substrate, and the male seat is arranged on the flexible board substrate and is located on the same side surface of the flexible board substrate as the dielectric element.

Furthermore, the dielectric element and the male seat are respectively located at two opposite ends of the flexible board substrate, and the dielectric element and the supporting plate are both located at the same end of the flexible board substrate.

Furthermore, the electrode unit also includes a temperature sensor which is arranged on the flexible board substrate and is located on the same side as the dielectric element.

Furthermore, the dielectric element has a penetrating opening, and the temperature sensor is accommodated in the opening of the dielectric element.

Furthermore, the electrode unit and the adapter plate are adhered to the backing in a partially overlapping manner, and the male seat and the corresponding female seat are located at the overlapping position.

Furthermore, the adapter plate includes a main body and a wiring portion connected to the main body, at least one female socket of the adapter plate is arranged on the main body, and the wiring portion is located at one end of the main body.

Furthermore, the main body has a trunk, and the at least one female seat is located on the trunk.

Furthermore, the trunk of the main body is provided with at least one hollow hole arranged in a through-shape, and the hollow hole is arranged corresponding to the corresponding female seat.

Furthermore, the hollow holes allow the dielectric elements of the corresponding electrode units to pass through, and the dielectric elements of the electrode units are exposed to a side of the adapter plate away from the female seat when the electrode units are assembled on the adapter plate.

Furthermore, the main body also includes a plurality of branches located on both sides of the main trunk. The female seat is arranged on the branch.

Furthermore, there is a gap between two adjacent branches located on the same side of the trunk to allow the dielectric element of the corresponding electrode unit to pass through, and the dielectric element of the electrode unit is exposed to the side of the adapter plate away from the mother seat after passing through the gap.

Furthermore, the electrode patch also includes a wire electrically connected to the wiring portion of the adapter plate, one end of the wire is electrically connected to the wiring portion of the adapter plate, and the other end is provided with a plug.

Furthermore, a circle of heat shrink tubing is provided around the connection between the wire and the wiring portion.

Furthermore, the plug of the wire can be detachably plugged into a switching wire.

Furthermore, the backing is in sheet form and has at least one through hole corresponding to the electrode unit and arranged in a penetrating shape, and the through hole of the backing allows a corresponding portion of the electrode unit to be exposed on a side surface of the backing away from the adapter plate.

Furthermore, the electrode patch also includes a support member surrounding the corresponding part of the electrode unit and adhered to the backing, and an adhesive member covering the support member and the corresponding part of the electrode unit and adhered to the body surface skin corresponding to the tumor site of the patient.

Furthermore, the support member has at least one through hole arranged in a penetrating shape.

Furthermore, the through-holes include first through-holes corresponding to the corresponding electrode units and accommodating corresponding parts of the corresponding electrode units.

Furthermore, the through-holes further include a second through-hole located between the plurality of the first through-holes and opposite to the adapter plate.

Furthermore, the electrode patch also includes at least one release paper located on a side of the adhesive component away from the backing and covering the adhesive component and the backing.

Furthermore, the electrode unit includes a flexible board substrate and a dielectric element and a male seat respectively disposed at opposite ends of the same side of the flexible board substrate. A first AC line electrically connected to both the dielectric element and the male socket is embedded therein. The first AC line is arranged in a ring shape along the periphery of the flexible board substrate and forms two sections of lines electrically connecting the male socket and the dielectric element.

Furthermore, the dielectric element has an opening arranged in a penetrating shape.

Furthermore, the electrode unit further includes a temperature sensor disposed on the flexible board substrate. The temperature sensor is received in the opening of the dielectric element and is located on the same side of the flexible board substrate as the dielectric element.

Furthermore, the temperature sensor has a ground terminal and a signal terminal.

Furthermore, a first grounding wire electrically connected to the grounding end of the temperature sensor and the male socket and a first signal wire electrically connected to the signal end of the temperature sensor and the male socket and transmitting a temperature signal are also embedded in the flexible board substrate.

Furthermore, the flexible board substrate is also provided with a plurality of conductive pads arranged at intervals and welded to the dielectric element, two first pads welded to the ground terminal and the signal terminal of the temperature sensor respectively, and a plurality of second pads welded to the male socket.

Furthermore, the conductive pad and the first pad are located at the same end of the flexible board substrate, the second pad is located at the other end of the flexible board substrate, and two first pads are located at the middle position surrounded by the plurality of conductive pads.

Further, the first soldering pad welded to the ground end of the temperature sensor is connected to the first ground line, and the first soldering pad welded to the signal end of the temperature sensor is connected to the first signal line.

Furthermore, there are multiple, and at least 4, second pads.

Furthermore, two of the plurality of second pads are respectively connected to two of the first ground line, the first signal line and the first AC line, and the remaining second pads of the plurality of second pads are all commonly connected in series to the remaining one of the first ground line, the first signal line and the first AC line.

Further, two of the plurality of second pads are respectively connected to the first ground line and the first signal line, and the remaining second pads of the plurality of second pads are all commonly connected in series to the first AC line.

Furthermore, the electrode unit further includes a support plate, and the support plate and the dielectric element are respectively located on two opposite sides of the flexible board substrate and correspond one to one along the thickness direction.

Furthermore, a reinforcing plate is attached to the surface of the flexible board substrate on a side away from the male seat, and the reinforcing plate and the male seat are both located at one end of the flexible board substrate.

Furthermore, the electrode unit includes a flexible board substrate, and a dielectric element and a male socket respectively disposed at two opposite ends of the flexible board substrate, and the male socket is electrically connected to the dielectric element through two sections of circuits of the flexible board substrate.

Furthermore, three first conductive traces are embedded in the flexible board substrate, and the three first conductive traces are respectively a first grounding line, a first signal line, and a first AC line arranged in a ring shape.

Furthermore, the two sections of the line together constitute the first AC line, and the male socket is electrically connected to the dielectric element through the two sections of the first AC line.

Furthermore, the first AC line is arranged in a ring shape along the periphery of the flexible board substrate and is in a two-section structure with the head and tail electrically connected at the location where the male socket is arranged on the flexible board substrate.

Furthermore, the electrode unit also includes a temperature sensor disposed on the flexible board substrate, the temperature sensor and the dielectric element are located on the same side and have a ground terminal and a signal terminal.

Furthermore, the dielectric element has an opening arranged in a through shape, and the temperature sensor is accommodated in the opening.

Furthermore, the first grounding wire is electrically connected to the grounding end of the temperature sensor and the male socket, and the first signal wire is electrically connected to the signal end of the temperature sensor and the male socket to transmit a temperature signal.

Furthermore, the first ground line and the first signal line are both located within an area surrounded by the first AC line.

Furthermore, the electrode unit further comprises a support plate, the support plate is located on a side of the flexible board substrate away from the dielectric element, and the support plate corresponds to the dielectric element in a one-to-one manner along a thickness direction.

Furthermore, a reinforcing plate is attached to a surface of the flexible board substrate on a side away from the male seat, and the reinforcing plate and the male seat are located at the same end of the flexible board substrate.

Furthermore, the adapter plate includes at least one female socket, and the male socket of the electrode unit is detachably connected to a corresponding female socket of the adapter plate.

Furthermore, the electrode patch also includes a wire electrically connected to the adapter plate, a backing adhered to the electrode unit and corresponding parts of the adapter plate, a support member surrounding the corresponding part of the electrode unit and adhered to the backing, and an adhesive member covering the support member and the corresponding part of the electrode unit and adhered to the surface skin of the patient corresponding to the tumor site.

The present invention also provides the following technical solution: an electrode patch for electric field therapy of tumors, comprising a plurality of electrode units, an adapter board formed by a flexible circuit board, and a backing, wherein the plurality of electrode units and the adapter board are adhered to the backing, the adapter board partially overlaps with each of the electrode units and forms a detachable electrical plug connection with each of the electrode units at the overlapping portion, a second AC line for transmitting an alternating electrical signal is embedded in the adapter board, and the plurality of electrode units are connected in parallel to the second AC line of the adapter board.

Furthermore, each of the electrode units includes a flexible board substrate, a support plate and a dielectric element respectively arranged on both sides of the flexible board substrate, and a male seat arranged on the flexible board substrate, and the dielectric element and the male seat are electrically connected to the flexible board substrate and are respectively located at opposite ends of the flexible board substrate.

Furthermore, the adapter plate is provided with a plurality of female sockets detachably connected to the male sockets corresponding to the electrode units, and the plurality of female sockets are all connected in parallel to the second AC line.

Furthermore, the corresponding dielectric elements of the plurality of electrode units are connected in parallel to the second AC line of the adapter board through the male sockets provided on the flexible board substrate and connected to the female sockets of the adapter board.

Furthermore, each of the electrode units includes a temperature sensor electrically connected to the flexible board substrate, the temperature sensor and the dielectric element are located on the same side and have a ground terminal and a signal terminal.

Furthermore, the dielectric element is provided with a through opening, and the temperature sensor is accommodated in the opening.

Furthermore, a second grounding line for transmitting a grounding signal to the temperature sensor and multiple second signal lines for transmitting temperature signals sensed by the temperature sensor in parallel are embedded inside the adapter board.

Furthermore, the ground ends of the corresponding temperature sensors of the multiple electrode units are connected in parallel to the second ground line of the adapter board through the male socket provided on the flexible board substrate and the corresponding female socket of the adapter board, and the signal ends of the corresponding temperature sensors of the multiple electrode units are electrically connected to the corresponding second signal line of the adapter board through the male socket provided on the flexible board substrate and the corresponding female socket of the adapter board.

Furthermore, the second AC line and the second ground line are both arranged in a dendrite-like wiring pattern.

Furthermore, the adapter plate has a main body that can be detachably connected to the plurality of electrode units and a wiring portion, and the plurality of female sockets are arranged on the main body in an interval shape.

Furthermore, the main body also has a trunk and at least one branch, and the multiple mother seats are arranged at intervals on the trunk and the branch respectively.

Furthermore, it also includes a wire welded to the wiring portion.

Furthermore, a heat shrink tubing is provided around the welding point between the wiring part and the wire.

Furthermore, multiple fourth pads are provided on both side surfaces of the wiring part, and the multiple fourth pads are all welded to the wire. The multiple fourth pads include multiple conductive pads electrically connected to the corresponding second AC line, second ground line and second signal line, and virtual pads that are not electrically connected to the second AC line, the second ground line and the second signal line.

Furthermore, the dielectric elements of the plurality of electrode units are exposed toward a side of the adapter plate away from the female base.

Furthermore, the electrode patch also includes a support member that surrounds the corresponding parts of the multiple electrode units and is adhered to the backing, and an adhesive member that covers the support member and the corresponding parts of the multiple electrode units and is adhered to the body surface skin corresponding to the patient's tumor site.

The present invention also provides the following technical solutions: A method for manufacturing the aforementioned electrode patch, comprising the following steps: S11, providing an adapter board, the adapter board having at least one group of third solder pads and a wiring portion; S12, providing at least one mother seat, and welding the mother seats to the corresponding third solder pads of the adapter board respectively; S13, providing a wire, and setting the wire group at the wiring portion of the adapter board; S14, providing a heat shrink tubing, and covering the heat shrink tubing at the connection between the adapter board and the wire; S15, providing at least one electrode unit detachably connected to the adapter board, and clamping the electrode unit to the mother seat on the adapter board; S16, providing a backing, and gluing the corresponding part of the surface of one side of the adapter board on which the mother seat is set after completing the above steps and the surface on the same side of the electrode unit to the backing.

Furthermore, after step S16, the following steps are also included: S17, providing a support member, and bonding the support member to the backing in a surrounding shape surrounding the corresponding part of the electrode unit; S18, providing an adhesive member, and adhering the adhesive member to the surface of the support member and the corresponding part of the electrode unit away from the backing; S19, providing a release paper, and covering the release paper on the surface of the backing and the adhesive member close to the patient's skin.

Furthermore, the manufacturing method of the electrode unit comprises the following steps: S21, providing a flexible board substrate, wherein one end of the flexible board substrate has a plurality of conductive pads arranged in a spaced manner and two first pads located in an area surrounded by the plurality of conductive pads, and the other end has a plurality of second pads; S22, Provide a support plate, and respectively assemble the support plate on the flexible board substrate in a one-to-one correspondence with the multiple conductive plates, and the support plate and the conductive plates are respectively located on opposite sides of the flexible board substrate; S23, provide a temperature sensor, and weld the temperature sensor on the two first pads; S24, provide a dielectric element with an opening, and weld the dielectric element on the multiple conductive plates in a manner that the corresponding temperature sensors are accommodated in the opening; S25, provide a male socket, and weld the male socket on the multiple second pads.

The present invention also provides the following technical solution: a tumor electric field therapeutic device, comprising an electric field generator and at least one pair of the aforementioned electrode patches electrically connected to the electric field generator.

Furthermore, the tumor electric field therapy device also includes an adapter electrically connected between the electrode patch and the electric field generator.

The electrode patch of the tumor electric field therapy device of the present invention is composed of at least one electrode unit and a removable connection with an adapter plate, which can realize the removable replacement of a failed electrode unit on the electrode patch, or the removable replacement of a failed adapter plate on the electrode patch, thereby avoiding the replacement of the entire electrode patch and reducing the yield loss of the electrode patch.

It should be understood that the foregoing general description and the following detailed description are exemplary and explanatory only and are not restrictive of the present application.

BRIEF DESCRIPTION OF THE DRAWINGS

FIG1A is a schematic diagram of an assembly of electrode patches of a tumor electric field therapeutic apparatus according to a first embodiment of the present invention;

FIG1B is an overall schematic diagram of the electrode patch in FIG1A from another perspective;

FIG2 is a partial schematic diagram of the electrode patch in FIG1B , wherein the release paper is not shown;

FIG3A is an exploded schematic diagram of the electrode unit in FIG2 ;

FIG3B is a schematic diagram of the assembly of the electrode unit in FIG2 ;

FIG4 is a wiring diagram of the flexible board substrate of the electrode unit in FIG3A;

FIG5 is a schematic diagram of the structure of the adapter plate in FIG2 ;

FIG6A is a front wiring diagram of the adapter board in FIG5 ;

FIG6B is a wiring diagram of the reverse side of the adapter board in FIG5 ;

FIG7A is a schematic diagram of an assembly of the electrode unit, adapter plate, wire and backing in FIG2 ;

FIG7B is a schematic diagram of another combination of the electrode unit, adapter plate, wire and backing in FIG2 ;

FIG8 is a schematic diagram of the assembly of the electrode unit, adapter plate, wire, backing and support member in FIG1 ;

9A is an exploded schematic diagram of an electrode patch of a tumor electric field therapeutic apparatus according to a second embodiment of the present invention, wherein the release paper is not shown;

FIG9B is a schematic diagram of the assembly of the electrode patch shown in FIG9A , wherein the release paper is not shown;

FIG10A is an exploded schematic diagram of the adapter plate and the wires in FIG9A ;

FIG10B is a schematic diagram of the combination of the adapter plate and the wire in FIG10A ;

FIG11A is a front wiring diagram of the adapter board in FIG10A ;

FIG11B is a wiring diagram of the reverse side of the adapter board in FIG10A;

FIG12 is a schematic flow chart of a method for manufacturing an electrode patch of a tumor electric field therapeutic apparatus according to the present invention;

FIG13 is a schematic flow chart of a method for manufacturing an electrode unit of the electrode patch described in FIG12;

FIG. 14 is a schematic diagram of a tumor electric therapy field apparatus according to the first embodiment and the second embodiment of the invention.

Detailed ways

The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

Exemplary embodiments will be described in detail herein, examples of which are shown in the accompanying drawings. When the following description refers to the drawings, unless otherwise indicated, the same numbers in different drawings represent the same or similar elements. The implementations described in the following exemplary embodiments do not represent all implementations consistent with the present application. Instead, they are merely examples of devices and methods consistent with some aspects of the present application as detailed in the appended claims.

FIG14 is a tumor electric field therapy device 1000 of the present invention, which includes an electric field generator 200 and electrode patches 100, 100' connected to the electric field generator 200. The electrode patches 100, 100' are applied to the surface of human skin, and the therapeutic electric field generated by the electric field generator 200 acts on the human body to perform tumor electric field therapy. The electrode patches 100, 100' of the embodiment of the present application are applied to the human head for use as an auxiliary treatment for brain tumors, such as glioblastoma multiforme. In other embodiments, an adapter 300 can also be provided between the electrode patches 100, 100' and the electric field generator 200 of the tumor electric field therapy device 1000. The adapter 300 is electrically connected between the electrode patches 100, 100' and the electric field generator 200.

FIG1 to FIG8 show an electrode patch 100 according to a first embodiment of the present invention. The electrode patch 100 can be directly plugged into the electric field generator 200 to realize the electrical connection between the electrode patch 100 and the electric field generator 200, or can be directly plugged into the adapter 300, and then electrically connected to the electric field generator 200 through the adapter 300 to realize the electrical connection between the electrode patch 100 and the electric field generator 200. The electrode patch 100 includes at least one electrode unit 10, an adapter plate 20 detachably connected to at least one electrode unit 10, a wire 30 electrically connected to the adapter plate 20, a backing 40 adhered to corresponding parts of the electrode unit 10 and the adapter plate 20, a support member 50 surrounding the corresponding part of the electrode unit 10 and adhered to the backing 40, and a support member 50 covering the support member 50 and the corresponding part of the electrode unit 10 and corresponding to the tumor site of the patient. The adhesive piece 60 is attached to the body surface skin. The electrode patch 100 is attached to the body surface corresponding to the patient's tumor site through the backing 40, and applies an alternating electric field to the patient's tumor site through at least one electrode unit 10 detachably connected to the adapter plate 20 to interfere with or prevent the mitosis of the patient's tumor cells, thereby achieving the purpose of treating the tumor. The present invention forms an electrode patch 100 by detachably connecting at least one electrode unit 10 to the adapter plate 20, which can realize the detachable replacement of a failed electrode unit 10, or the detachable replacement of a failed adapter plate 20, which can reduce the loss of the entire electrode patch 100 before the product is shipped, reduce the yield loss of the electrode patch 100, and avoid causing the entire electrode patch 100 to be scrapped when the electrode patch 100 is used, saving costs; the intensity of the alternating electric field applied by the electrode patch 100 can also be adaptively adjusted according to the size of the tumor by freely selecting the number of electrode units 10 plugged into the adapter plate 20.

3A and 3B , each electrode unit 10 includes a flexible board substrate 11, a support plate 13 and a dielectric element 12 respectively disposed on both sides of the flexible board substrate 11, and a male seat 15 disposed on the same side surface of the flexible board substrate 11 and the dielectric element 12. The dielectric element 12 and the male seat 15 are respectively located at opposite ends of the flexible board substrate 11, and the dielectric element 12 and the support plate 13 are located at the same end of the flexible board substrate 11. In this embodiment, the size of the support plate 13 and the dielectric element 12 are slightly smaller than the size of the flexible board substrate 11.

The dielectric element 12 is made of a high dielectric constant material, which has a conductive property of blocking the conduction of direct current and allowing alternating current to pass, which can ensure the safety of the user during electric field therapy of tumors. The center of the dielectric element 12 has an opening 121 that runs through it. The electrode unit 10 also includes a temperature sensor 14 that is arranged on the flexible board substrate 11 and is located on the same side as the dielectric element 12. The temperature sensor 14 is accommodated in the opening 121 in the center of the dielectric element 12 to sense the temperature of the patient's skin attached to the electrode patch 100. The temperature sensor 14 has a ground terminal 14A and a signal terminal 14B. Preferably, the temperature sensor 14 is a thermistor.

Referring to FIG. 4 , three first conductive traces 114 are embedded in the flexible board substrate 11. The three first conductive traces 114 include a first grounding trace 114A electrically connected to the ground terminal 14A of the temperature sensor 14 and the male socket 15, a first signal terminal 14B electrically connected to the signal terminal 14B of the temperature sensor 14 and the male socket 15, and a second signal terminal 14C electrically connected to the signal terminal 14C of the temperature sensor 14 and the male socket 15. The first signal line 114B for transmitting the temperature signal connected thereto and a first AC line 114C arranged in a ring shape and electrically connected to the dielectric element 12 and the male socket 15. The first grounding line 114A and the first signal line 114B are both extended along the length direction of the flexible board substrate 11. The first AC line 114C is arranged in a ring shape along the periphery of the flexible board substrate 11 and is in a two-segment structure electrically connected end to end at the position where the male socket 15 is arranged on the flexible board substrate 11, that is, the male socket 15 is electrically connected to the dielectric element 12 through two sections of lines. Therefore, when one section of the first AC line 114C is broken due to bending, the other section of the first AC line 114C can also transmit the electrical signal to the dielectric element 12, thereby ensuring the electrical reliability of the electrode unit 10, improving the product quality and reducing the product defect rate. The first grounding line 114A and the first signal line 114B are both located inside the annular first AC line 114C to facilitate wiring and reduce wiring difficulty.

Specifically, the first AC line 114C is arranged in a closed ring along the periphery of the flexible board substrate 11, and includes a first AC line segment 115 located at the same end as the dielectric element 12 and arranged in an arc shape, and a second AC line segment 116 extending from the first AC line segment 115 and arranged in an inverted "Π" shape. The first AC line segment 115 is electrically connected to the dielectric element 12 arranged on the flexible board substrate 11. One end of the second AC line segment 116 is connected to both opposite ends of the first AC line segment 115, and the other end is welded to the male socket 15 arranged on the flexible board substrate 11. The electrode unit 10 is electrically connected to the first AC line segment 115 of the first AC line 114C of the flexible board substrate 11 through the dielectric element 12, the first AC line segment 115 of the first AC line 114C of the flexible board substrate 11 is connected to one end of the second AC line segment 116, and the other end of the second AC line segment 116 of the first AC line 114C of the flexible board substrate 11 is electrically connected to the male socket 15 to achieve electrical connection between the dielectric element 12 and the male socket 15.

The second AC line segment 116 is formed by extending the opposite ends of the first AC line segment 115 along the length direction of the flexible board substrate 11 and then closing at the end away from the first AC line segment 115. The second AC line segment 116 first extends from one end of the first AC line segment 115 in a direction away from the dielectric element 12, then bends and extends toward the other end of the first AC line segment 115, and then extends toward the other end of the first AC line segment 115 until it is connected to the other end of the first AC line segment 115. The second AC line segment 116 includes a portion extending from one end of the first AC line segment 115 and forming an "L" shape, and a portion extending from the other end of the first AC line segment 115 and forming an "I" shape. The second AC line segment 116 has two parts connected to two opposite ends of the first AC line segment 115 respectively. When one part is disconnected from one end of the first AC line segment 115 due to bending, the other part can be connected to the other end of the first AC line segment 115 to ensure the electrical connection between the first AC line segment 115 and the first AC line segment 115, thereby achieving a good and stable electrical connection between the dielectric element 12 and the male socket 15. That is, the second AC line segment 116 of the first AC line 114C is connected to the two opposite ends of the arc-shaped first AC line segment 115 at the same time. Even when the second AC line segment 116 is disconnected from one end of the first AC line segment 115 due to bending, the electrical signal can still be transmitted to the dielectric element 12 through the connection between the second AC line segment 116 and the other end of the first AC line segment 115, thereby ensuring the reliability of the electrical connection between the dielectric element 12 of the electrode unit 10 and the flexible board substrate 11, thereby improving the product quality and reducing the product defect rate. The first ground line 114A and the first signal line 114B are both located in the area circled by the first AC line 114C to facilitate wiring and reduce wiring difficulty.

The same side surface of the flexible board substrate 11 is also provided with a plurality of conductive pads 111 arranged in an interval shape and welded to the dielectric element 12, two first pads 112 respectively welded to the ground terminal 14A and the signal terminal 14B of the temperature sensor 14, and a plurality of second pads 113 welded to the male socket 15. The conductive pads 111 and the first pads 112 are both located at the same end of the flexible board substrate 11, and the second pads 113 are located at the other end of the flexible board substrate 11. The plurality of conductive pads 111 are respectively electrically connected to the first AC line segment 115 of the first AC line 114C embedded in the flexible board substrate 11, and are connected in series through the arc-shaped first AC line segment 115. The flexible board substrate 11 is electrically connected to the dielectric element 12 through the first AC line segment 115 of the first AC line 114C being electrically connected to the conductive pads 111 and the conductive pads 111 being welded to the dielectric element 12.

The two first pads 112 are located in the middle of the plurality of conductive pads 111. The first pad 112 soldered to the ground terminal 14A of the temperature sensor 14 is the first pad 112A, and the first pad 112 soldered to the signal terminal 14B of the temperature sensor 14 is the first pad 112B. The first pad 112A is located at the end of the first ground line 114A located in the first AC line segment 115 of the first AC line 114C, and the first pad 112B is located at the end of the first signal line 114B located in the first AC line segment 115 of the first AC line 114C. The first pad 112A is electrically connected to one end of the first ground line 114A. The first pad 112B is electrically connected to one end of the first signal line 114B. The flexible board substrate 11 realizes electrical connection with the temperature sensor 14 by welding the ground end 14A of the temperature sensor 14 to the first pad 112A connected to the first ground line 114A and welding the signal end 14B of the temperature sensor 14 to the first pad 112B connected to the first signal line 114B.

The second pads 113 and the first pads 112 are respectively disposed at opposite ends of the flexible board substrate 11. The second pads 113 are disposed at one end of the flexible board substrate 11 away from the dielectric element 12 and are welded to the male socket 15 to achieve electrical connection between the second pads 113 and the male socket 15. There are at least three second pads 113, including a second pad 113A electrically connected to the first pad 112A through the first grounding line 114A, a second pad 113B electrically connected to the first pad 112B through the first signal line 114B, and at least one second pad 113C electrically connected to the conductive pad 111 through the first AC line 114C. The second pads 113A and the first pads 112A are respectively disposed at opposite ends of the first grounding line 114A, and are electrically connected to each other through the first grounding line 114A. The second pad 113B and the first pad 112B are respectively disposed at two opposite ends of the first signal line 114B, and the electrical connection between the two is realized through the first signal line 114B. The second pad 113C and the conductive pad 111 are respectively disposed at two opposite ends of the first AC line 114C, and the electrical connection between the two is realized through the first AC line 114. The second pad 113C is disposed at the end of the second AC line segment 116 of the first AC line 114, and the conductive pad 111 is disposed on the first line segment 115 of the first AC line 114. The flexible board substrate 11 realizes the electrical connection between the male socket 15 and the dielectric element 12 by welding the conductive pad 111 disposed on the first AC line segment 115 of the first AC line 114C to the dielectric element 12, and welding the second pad 113C disposed at the end of the second line segment 116 of the first AC line 114C to the male socket 15. The flexible board substrate 11 realizes electrical connection between the temperature sensor 14 and the male socket 15 by welding a first soldering pad 112A at one end of the first grounding wire 114A to the grounding terminal 14A of the temperature sensor 14, welding a first soldering pad 112B at one end of the first signal wire 114B to the signal terminal 14B of the temperature sensor 14, and welding a second soldering pad 113A at the other end of the first grounding wire 114A and a second soldering pad 113B at the other end of the first signal wire 114B to the male socket 15.

There are at least three second solder pads 113 soldered to the male socket 15. When the second pads 113 are welded to the flexible board substrate 11, the welding of the male socket 15 and the flexible board substrate 11 is firm, ensuring a good electrical connection between the male socket 15 and the flexible board substrate 11. And the conductive disk 111 is welded to the male socket 15 through at least one second pad 113C provided on the second AC line segment 116 of the first AC line 114C, which can ensure a stable electrical connection between the conductive disk 111 and the male socket 15, so that the electrical signal for tumor treatment is transmitted to the conductive disk 111 through the first AC line 114C, and then transmitted to the dielectric element 12 through the conductive disk 111. In this embodiment, four second pads 113C welded to the male socket 15 are respectively connected to the second AC line segment 116 of the first AC line 114C. In order to achieve the purpose of strengthening the welding firmness of the male socket 15 and the flexible board substrate 11 of the present application, the present application can also have other implementation methods. For example, one of the plurality of second pads 113 is connected to the first ground line 114A, one is connected to the second AC line segment 116 of the first AC line 114C, and the remaining ones are connected to the corresponding first signal lines 114B in a one-to-one correspondence. For another example, one of the plurality of second pads 113 is connected to the first signal line 114B, one is connected to the first AC line 114C, and the remaining ones are connected to the first ground line 114A. That is, two of the plurality of second pads 113 are respectively connected to two lines among the first ground line 114A, the first signal line 114B, and the first AC line 114C, and the remaining second pads 113 are all connected to the remaining one line among the first ground line 114A, the first signal line 114B, and the first AC line 114C.

The grounding signal of the temperature sensor 14 is transmitted to the corresponding second pad 113A electrically connected to the first grounding wire 114A through the first grounding wire 114A electrically connected to the grounding terminal 14A; the temperature signal detected by the temperature sensor 14 is transmitted to the corresponding second pad 113B electrically connected to the first signal wire 114B through the first signal wire 114B electrically connected to its signal terminal 14B; and the temperature signal detected by the temperature sensor 14 is transmitted to the electric field generator 200 by welding the second pad 113 to the male socket 15, plugging the male socket 15 to the adapter board 20, electrically connecting the adapter board 20 to the wire 30, and plugging the wire 30 to the electric field generator 200, thereby achieving the purpose of the electric field generator 200 controlling the alternating electric signal transmitted to the dielectric element 12 through the detected temperature signal, thereby avoiding low-temperature burns on the patient's tumor surface caused by excessive temperature. The AC signal generated by the electric field generator 200 is transmitted to the first AC line 114C arranged in a ring shape through the corresponding at least two second pads 113C, and then connected to the first AC line 114C. The AC line 114C welded with the plurality of conductive plates 111 is transmitted to the dielectric element 12 to apply an AC electric signal to the tumor site for tumor electric field therapy. The AC signal required by the dielectric element 12 is an alternating current signal, which is output by the electric field generator 200. The electric field generator 200 also outputs a direct current signal to the temperature sensor 14, so that the temperature sensor 14 is connected to the ground signal and operates to generate a temperature signal.

The support plate 13 is bonded to the surface of one side of the flexible board substrate 11 away from the conductive disk 111 by an adhesive (not shown). The support plate 13 corresponds to the dielectric element 12 one by one along the thickness direction. The temperature sensor 14 is welded and arranged at the position of the flexible board substrate 11 corresponding to the two first pads 112, the dielectric element 12 is welded and arranged at the position of the flexible board substrate 11 corresponding to the multiple conductive disks 111, and the male seat 15 is welded and arranged at the position of the second pad 113 of the flexible board substrate 11. The temperature sensor 14, the dielectric element 12 and the support plate 13 are all arranged at the same end of the flexible board substrate 11. When welding the temperature sensor 14 and the dielectric element 12, the support plate 13 provides strength support for the flexible board substrate 11, and provides a flat welding plane for the welding operation between the flexible board substrate 11 and the temperature sensor 14 and the dielectric element 12, thereby improving the product yield. A reinforcing plate 16 is attached to one end of the flexible board substrate 11 where the male socket 15 is welded. The reinforcing plate 16 is arranged on the surface of the flexible board substrate 11 opposite to the male socket 15 to provide strength support for the flexible board substrate 11 so that the male socket 15 can be welded thereto. At the same time, it also prevents the male socket 15 of the electrode unit 10 from bending the welding part between the flexible board substrate 11 and the male socket 15 when plugging and unplugging the adapter board 20, thereby preventing the conductive traces embedded in the flexible board substrate 11 from breaking. The reinforcing plate 16 and the male socket 15 are respectively arranged on opposite sides of the flexible board substrate 11. The reinforcing plate 16 and the male socket 15 are located at the same end of the flexible board substrate 11.

The adapter plate 20 is provided with at least one female socket 25 corresponding to and electrically connected to the male socket 15 of the electrode unit 10. A plurality of electrode units 10 can be plugged and combined with the corresponding female socket 25 on the adapter plate 20 through the corresponding male socket 15 to form an electrode patch 100 having at least one electrode unit 10. The present invention can realize the detachable replacement of a failed electrode unit 10 or the detachable replacement of a failed adapter plate 20 by means of the detachable combination of the electrode unit 10 and the adapter plate 20, thereby avoiding the scrapping of the entire electrode patch 100 and reducing the yield loss of the electrode patch 100; avoiding the scrapping of the entire electrode patch 100, avoiding waste and reducing costs; and at the same time, the electrode units plugged into the adapter plate 20 can be freely combined and selected. 10 quantity is used to increase or decrease the electric field strength generated by the electrode patch 100 to ensure that the electrode patch 100 generates the electric field strength of the required size at the patient's tumor site.

The adapter plate 20 is provided in a sheet shape, and has a body 28 for plugging and combining at least one electrode unit 10 and a wiring portion 27 for electrically connecting a wire 30. The wiring portion 27 is provided integrally with the body 28. The wiring portion 27 is located at one end of the body 28. The female seat 25 plugged with the male seat 15 of the electrode unit 10 is provided on the body 28 by welding. The wire 30 is electrically connected to the adapter plate 20 by welding with the wiring portion 27. The electrode unit 10 of the electrode patch 100 is electrically connected to the adapter plate 20 by plugging its male seat 15 with the female seat 25 welded on the adapter plate 20, and the adapter plate 20 is electrically connected to the wire 30 by welding its wiring portion 27 with the wire 30. The electrode unit 10 of the electrode patch 100 is electrically connected to the wire 30 through the adapter plate 20. Preferably, the adapter board 20 is a flexible circuit board, and multiple electrode units 10 are connected to the adapter board 20 in parallel. Even if the electrical connection between a certain electrode unit 10 and the adapter board 20 is interrupted, it will not affect the electrical connection between the remaining electrode units 10 and the adapter board 20.

Referring to FIG. 6A and FIG. 6B , the adapter plate 20 has at least one group of third pads 23 disposed on the body 28 and welded to the corresponding female seat 25, and a plurality of fourth pads 24 disposed on opposite sides of the wiring portion 27 and welded to the wire 30. The configuration of each group of third pads 23 is the same as the configuration of the second pad 113 of the electrode unit 10, and each group of third pads 23 has a plurality of third pads 23, one third pad 23A of the plurality of third pads 23 is connected to a ground signal, one third pad 23B is connected to a temperature signal, and the remaining third pads 23C are all connected to an AC signal. A group of fourth pads 24 has a plurality of fourth pads 24. The plurality of fourth pads 24 include a fourth pad 24A transmitting a ground signal, a fourth pad 24C transmitting an AC signal, and a plurality of fourth pads 24B transmitting corresponding temperature signals, respectively. The third pads 23A transmitting ground signals in the multiple groups of third pads 23 are all connected in parallel to a fourth pad 24A, the multiple third pads 23C transmitting AC signals in the multiple groups of third pads 23 are all connected in parallel to a fourth pad 24C, and the third pads 23B transmitting temperature signals in the multiple groups of third pads 23 are all connected one by one to the corresponding fourth pads 24B.

A plurality of second conductive traces 26 are embedded in the adapter board 20. The fourth pads 24A, 24B, and 24C are respectively arranged at opposite ends of the multi-channel second conductive traces 26, and the electrical connection between the two is achieved through the second conductive traces 26. Multiple groups of third pads 23 are arranged in parallel connection at one end of the multi-channel second conductive traces 26, and multiple electrode units 10 can be connected to the adapter board 20 in parallel after the multiple electrode units 10 are respectively plugged into the female sockets 25 welded to the multiple groups of third pads 23 through their corresponding male sockets 15, thereby making the signal transmission between each electrode unit 10 and the adapter board 20 independent and independent of each other. Even if one of the electrode units 10 is damaged, it will not affect the signal transmission between the remaining electrode units 10 and the adapter board 20, ensuring the normal operation of the remaining electrode units 10 without replacing or scrapping the entire electrode patch 100.

The multiple second conductive traces 26 include a second ground line 26A for transmitting a ground signal, a second AC line 26C for transmitting an AC signal, and multiple second signal lines 26B for transmitting corresponding temperature signals. The second AC line 26C transmits an AC signal, is arranged in a dendrite-like wiring, and is electrically connected to a third pad 23C connected to an AC signal in each group of third pads 23 and a fourth pad 24C connected to an AC signal in the fourth pad 24, so that each electrode unit 10 assembled with a mother seat 25 corresponding to the corresponding third pad 23 can be in an equipotential state, ensuring the AC signal stability of the electrode patch 100. A third pad 23C connected to an AC signal in each group of third pads 23 is connected to the second AC line 26C in parallel, that is, the AC signal of each electrode unit 10 assembled with a mother seat 25 corresponding to the corresponding third pad 23 does not affect each other. Even if an electrode unit 10 is damaged during use, it does not affect other electrode units 10 from continuing to apply an alternating electric field to the patient's tumor site for tumor electric field therapy. The second grounding wire 26A transmits a grounding signal, is arranged in a dendrite-like wiring, and is electrically connected to a third pad 23A connected to a grounding signal in each group of third pads 23, and a fourth pad 24A connected to a grounding signal in the fourth pad 24. A third pad 23A connected to a grounding signal in each group of third pads 23 is connected to the second grounding wire 26A in parallel, that is, the grounding signals of each electrode unit 10 assembled with the mother socket 25 corresponding to the corresponding third pad 23 are not affected by each other. The multiple second signal lines 26B transmit corresponding temperature signals respectively, and are electrically connected one-to-one with a third pad 23B connected to a temperature signal in a corresponding group of third pads 23, and a fourth pad 24B connected to a temperature signal in the group of fourth pads 24. By means of the connection relationship between the third pads 23, the fourth pads 24 and the multi-channel second conductive traces 26, at least one group of the third pads 23 is connected in parallel, so as to realize that at least one electrode unit 10 is connected in parallel to the adapter board 20, and the on and off of the AC signal, the ground signal and the temperature signal of each electrode unit 10 do not affect each other.

That is, multiple third pads 23C are connected to the second AC line 26C in parallel. Multiple third pads 23A are also connected to the second ground line 26A in parallel. Multiple third pads 23B are respectively connected to their corresponding signal lines 26B, and are connected to their corresponding fourth pads 24B through their corresponding signal lines 26B. Each female socket 25 is arranged in parallel on the adapter board 20 by welding with the corresponding group of third pads 23. After each electrode unit 10 is plugged into the corresponding female socket 25 through its corresponding male socket 15, each electrode unit 10 can be connected to the adapter board 20 in parallel, so that the signal connection and disconnection between each electrode unit 10 and the adapter board 20 do not affect each other. Even if one of the electrode units 10 is damaged or the electrical connection between it and the adapter board 20 is disconnected, it will not affect the electrical connection and signal transmission between the remaining electrode units 10 and the adapter board 20.

The plurality of third pads 23A for transmitting ground signals and the fourth pad 24A for transmitting ground signals are respectively arranged at opposite ends of a second ground line 26A, and the electrical connection between the corresponding third pads 23A and the fourth pad 24A is realized through the second ground line 26A, and the plurality of third pads 23A are arranged in parallel connection at one end of the second ground line 26A, so that after the plurality of electrode units 10 are plugged into the corresponding female sockets 25 of the adapter board 20, the ground signal transmission of each electrode unit 10 is independent and does not affect each other. One end of each second signal line 26B for transmitting temperature signals is connected to a third pad 23B for transmitting temperature signals, and the other end is connected to a fourth pad 24B for transmitting temperature signals and corresponding to the third pad 23B, so as to respectively transmit the temperature signals collected by the temperature sensors 14 of each electrode unit 10, so that after each electrode unit 10 is plugged into the adapter board 20, the temperature signal transmission between each electrode unit 10 is independent and does not affect each other.

A plurality of third pads 23C for transmitting AC signals and a fourth pad 24C for transmitting AC signals are respectively disposed at opposite ends of a second AC line 26C, and the electrical connection between the corresponding third pads 23C and the fourth pad 24C is realized through the second AC line 26C, and the plurality of third pads 23C and the fourth pad 24C are respectively disposed at opposite ends of a second AC line 26C. The pads 23C are all connected in parallel at one end of the second AC line 26C. The second AC line 26C for transmitting AC signals is wired in a dendrite shape, one end of which is electrically connected to one third pad 23C in each group of third pads 23, and the other end is electrically connected to one fourth pad 24C in the plurality of fourth pads 24, so that after each electrode unit 10 is plugged into the corresponding female socket 25 of the adapter board 20 through its corresponding male socket 15, the AC signal transmission of each electrode unit 10 can be independent and not affect each other.

In this embodiment, the number of the fourth pads 24 is greater than the number of the second conductive traces 26, and includes conductive pads 24A, 24B, and 24C electrically connected to the corresponding second conductive traces 26. The fourth pad 24 also includes a dummy pad 24D that is disconnected from the second conductive trace 26, which can enhance the welding firmness of the flexible transfer board 20 and the wire 30.

In this embodiment, the multiple second conductive traces 26 embedded in the adapter board 20 are arranged in two wiring layers to avoid mutual interference between the second conductive traces 26. In this embodiment, the second AC line 26C is distributed in one layer, and the second ground line 26A and the second signal line 26B are distributed in two wiring layers to avoid the second AC line 26C. In other embodiments, the multiple second conductive traces 26 embedded in the adapter board 20 are arranged in three wiring layers or more than three wiring layers, which can improve the flexibility of the wiring of the multiple second conductive traces 26.

As shown in Figures 5, 6A and 6B, in this embodiment, the adapter board 20 has a plurality of female sockets 25 respectively welded to the third pads 23 of the corresponding groups. The plurality of female sockets 25 are welded and arranged on the main body 28 at intervals. The main body 28 of the adapter board 20 also has a trunk 21 and at least one branch 22. The wiring portion 27 is located at one end of the trunk 21 of the main body 28. The second conductive trace 26 of the adapter board 20 is embedded in the trunk 21 and the branch 22 of the main body 28. The plurality of female sockets 25 are welded and arranged on a trunk 21 and at least one branch 22 at intervals, so that the plurality of electrode units 10 are arranged on the adapter board 20 at intervals through the plug-in cooperation of the female sockets 25 and the male sockets 15 of the electrode units 10, and the electrical connection between the plurality of electrode units 10 and the adapter board 20 is realized at the same time.

In this embodiment, the trunk 21 of the body 28 of the adapter plate 20 is provided with at least one hollow hole 211 arranged in a through shape. The hollow hole 211 of the body 28 of the adapter plate 20 can allow the dielectric element 12 of the corresponding electrode unit 10 to pass through, so that the dielectric element 12 of the corresponding electrode unit 10 can pass through. The dielectric element 12 of the corresponding electrode unit 10 can be exposed to the side of the adapter plate 20 away from the female seat 25, so that the dielectric element 12 of the corresponding electrode unit 10 can pass through the adapter plate 20 and be configured on the surface of human skin.

In this embodiment, the adapter plate 20 has a trunk 21 and four branches 22 extending from the trunk 21 to both sides, and two branches 22 are respectively arranged on both sides of the trunk 21. The branches 22 located on different sides of the trunk 21 are arranged in pairs. There is a gap 221 between two adjacent branches 22 located on the same side of the trunk 21 that allows the dielectric element 12 of the corresponding electrode unit 10 to pass through, so that the dielectric element 12 of the corresponding electrode unit 10 can be exposed to the side of the adapter plate 20 away from the mother seat 25, and then the dielectric element 12 of the corresponding electrode unit 10 can pass through the adapter plate 20 and be configured on the surface of human skin.

In this embodiment, 13 female sockets 25 are provided on the adapter plate 20, and the 13 female sockets 25 are respectively arranged on one trunk 21 and four branches 22 of the main body 28. Three female sockets are provided on the trunk 21, two female sockets are respectively provided on the two branches 22 close to the wiring part 27, and three female sockets are respectively provided on the other two branches 22. Two hollow holes 211 are provided through the trunk 21 to respectively accommodate the dielectric components of the corresponding electrode unit 10. The three female sockets 25 located on the trunk 21, the two hollow holes 211 provided on the trunk 21, and the wiring part 27 are all arranged in an axially symmetrical manner, and the straight lines where the axes of symmetry of the three coincide. As shown in Figure 5, the three female sockets 25 located on the trunk 21 and the two hollow holes 211 provided on the trunk 21 are arranged in a longitudinally aligned manner. Two of the three female sockets 25 on the trunk 21 are disposed on the same side of a hollow hole 211 away from the wiring portion 27 , and the other one is disposed at a position of the trunk 21 between the two hollow holes 211 .

The two female seats 25 provided on the branches 22 close to the connection portion 27 are arranged roughly in an "L" shape on the corresponding branches 22. The three female seats 25 provided on the branches 22 away from the connection portion 27 are arranged roughly in a "Π" shape with one end open on the corresponding branches 22, and the opening of the "Π" formed by the three female seats 25 faces the trunk 21. The multiple female seats 25 provided on the branches 22 are symmetrically arranged along the longitudinal symmetry axis of the trunk 21. Two of the five female seats 25 on the two branches 22 located on the same side of the trunk 21 are longitudinally aligned and respectively arranged at the ends of the corresponding branches 22, and the remaining three are longitudinally aligned and respectively arranged at the positions of the corresponding branches 22 close to the trunk 21. The three female seats 25 provided on the trunk 21 are arranged in a The four female seats 25 located on the branches 22 on opposite sides of the trunk 21 and close to the connection part 27 are arranged in a transverse alignment in pairs. Specifically, the two female seats 25 respectively arranged at the ends of the two branches 22 close to the connection part 27 are arranged in a transverse alignment, and the two female seats 25 respectively arranged on the two branches 22 close to the connection part 27 and close to the trunk 21 are also arranged in a transverse alignment. The two female seats 25 arranged on the two branches 22 away from the connection part 27 and located at the ends of the corresponding branches 22 are arranged in a transverse alignment, and two of the four female seats 25 arranged on the two branches 22 away from the connection part 27 and located at the position of the corresponding branches 22 close to the trunk 21 are arranged in a transverse alignment, and the other two are also arranged in a transverse alignment.

In this embodiment, the female sockets 25 located on the branches 22 are arranged at the edges of the corresponding branches 22, and the female sockets 25 located on the trunk 21 are arranged in a horizontal alignment with the corresponding female sockets 25 located on the branches 22, so as to facilitate the wiring arrangement of the second conductive traces 26 of the adapter board 20, so that each female socket 25 is connected and arranged on the adapter board 20 in parallel through the second conductive traces 26. As shown in combination with FIG. 5 and FIG. 7B, the electrode units 10 detachably connected to the female sockets 25 located at the ends of each branch 22 are horizontally assembled on the adapter board 20, and the electrode units 10 detachably assembled with the female sockets 25 located outside the ends of each branch 22 are longitudinally assembled on the adapter board 20. In other embodiments, since the electrode units 10 are connected to the adapter board 20 in parallel, the on and off of the AC signals, ground signals and temperature signals of each electrode unit 10 do not affect each other, and the number of the electrode units 10 detachably assembled on the adapter board 20 is less than the number of the female sockets 25 on the adapter board 20.

In conjunction with Figures 1A, 5, 6A and 6B, one end of the wire 30 is electrically connected to the wiring portion 27 of the adapter board 20, and the other end is provided with a plug 32. Preferably, the wire 30 is a Lemo female sheathed wire. The wire 30 has a plurality of wire cores (not shown), and each wire core (not shown) is respectively welded to the corresponding fourth pads 24 on the two side surfaces of the wiring portion 27. In this embodiment, the number of electrode units 10 of the electrode patch 100 is 13, and the number of wire cores (not shown) of the wire 30 is 16. Correspondingly, there are wire cores (not shown) welded to the fourth pads 24A, 24B, and 24C in the wire 30 that are energized, and there are wire cores (not shown) welded to the virtual pad 24D that are not energized. A circle of heat shrink tubing 31 is also provided around the welding point between the wire 30 and the wiring portion 27, which is used to weld the adapter board 20 and the wire 30. Sealing and insulation protection are performed to avoid breakage at the welding point between the adapter plate 20 and the wire 30, and at the same time, dust and water are prevented.

The wire 30 also includes a shielding grid wire (not shown) wrapped around the outer periphery of the plurality of wire cores (not shown). The fourth pad 24 also includes a shielding pad 24E located at the end of the wiring portion 27, which can be welded to the shielding grid wire (shown) of the wire 30 to shield the wire 30 and prevent external signals from interfering with the signals transmitted by the plurality of wire cores (not shown) of the wire 30. The shielding pad 24E for shielding and the fourth pad 24A for transmitting the ground signal are both connected to the second ground wire 26A of the second conductive trace 26.

As shown in Fig. 1A and Fig. 1B, the plug 32 of the wire 30 can also be plugged with an adapter wire 33, which can be plugged into the electric field generator 200 to realize the electrical connection between it and the electric field generator 200, or plugged into the adapter 300 through the adapter 300, and then plugged into the electric field generator 200 through the adapter 300 to realize the electrical connection between it and the electric field generator 200. The adapter wire 33 is detachably connected to the wire 30, which can not only increase or shorten the distance between the wire 30 and the electric field generator 200 or the adapter 300 as needed, but also can only scrap the wire 30 welded with the adapter plate 20 when the electrode patch 100 is scrapped and needs to be replaced, without scrapping the adapter wire 33, which can reduce costs and avoid unnecessary waste. The number of wire cores (not shown) of the adapter wire 33 is consistent with the number of wire cores (not shown) of the wire 30, and corresponds one to one. The adapter wire 33 is a Leimo double male sheathed wire.

The backing 40 is provided in a sheet shape, and has at least one through hole 41 corresponding to the electrode unit 10 and provided in a through shape. The through hole 41 of the backing 40 allows the corresponding part of the electrode unit 10 to expose the side surface away from the adapter plate 20, which is conducive to dissipating the heat generated by the electrode patch 100 during the tumor electric field therapy. In this embodiment, the support plate 13 of the electrode unit 10 passes through the through hole 41 of the backing 40 and exposes the side surface of the backing 40 away from the adapter plate 20. The size of the through hole 41 of the backing 40 is slightly larger than the size of the support plate 13.

The support member 50 is provided in a sheet shape and has a plurality of through holes 51 provided in a through shape. The plurality of through holes 51 of the support member 50 include a plurality of first through holes 51A distributed corresponding to the corresponding electrode units 10 and two second through holes 51B provided in a strip shape and located between the plurality of first through holes 51A. Each first through hole 51A accommodates the dielectric element 12 of the corresponding electrode unit 10. The surface on one side of the patient's body surface is flush with the surface on the side of the dielectric element 12 close to the patient's body surface, and the adhesive member 60 can be evenly covered on the support member 50 and the dielectric element 12, thereby improving the comfort of applying the electrode patch 100. The two second perforations 51B respectively correspond to the parts where the branches 22 are arranged laterally extending from the trunk 21 of the adapter plate 20, so that part of the heat of the electrode patch 100 can be transferred from the adapter plate 20 to the external environment through the backing 40 to achieve the purpose of heat dissipation. The two second perforations 51B are both long holes. The size of the first perforation 51A is slightly larger than the size of one end of the electrode unit 10 welded with the dielectric element 12. Preferably, the support member 50 is foam.

There are multiple adhesive pieces 60. Each adhesive piece 60 is roughly arranged in a strip-shaped sheet shape, which has double-sided adhesiveness, one side of which is in contact with the corresponding parts of the support member 50 and the dielectric element 12, and the other side is in contact with the patient's body surface. Preferably, the adhesive piece 60 is a conductive hydrogel. Each adhesive piece 60 covers the dielectric element 12 of at least one electrode unit 10. In this embodiment, there are 5 adhesive pieces 60, each covering the dielectric elements 12 of 2 or 3 electrode units 10. There are 3 adhesive pieces 60 arranged in parallel in the horizontal direction, and each covers the dielectric elements 12 of 3 electrode units 10; there are 2 adhesive pieces 60 arranged in parallel in the vertical direction, and each covers the dielectric elements 12 of 2 electrode units 10. The 2 adhesive pieces 60 arranged in parallel in the vertical direction are distributed on both sides of the 3 adhesive pieces 60 arranged in parallel in the horizontal direction.

The electrode patch 100 may further include at least one release paper 70. The release paper 70 is located on the side of the adhesive member 60 away from the backing 40 and covers the corresponding parts of the adhesive member 60 and the backing 40 to protect the adhesive member 60 and the backing 40 from being contaminated. In this embodiment, the electrode patch 100 has two release papers 70. The two release papers 70 cover the adhesive member 60 and the backing 40 together.

The electrode patch 100 of the first embodiment of the tumor electric field therapy device 1000 of the present invention is composed of multiple electrode units 10 and a removable connection with an adapter plate 20, and the multiple electrode units 10 are connected in parallel to the adapter plate 20. Therefore, the AC signals of the multiple electrode units 10 do not affect each other. Even if an electrode unit 10 is damaged during use, it does not affect other electrode units 10 to continue to apply an alternating electric field to the patient's tumor site for tumor electric field therapy, which improves the stability of the electrical signal of the tumor electric field therapy and can reduce the patient's treatment cost to a certain extent.

9 to 11 show an electrode patch 100' according to a second embodiment of the present invention. The electrode patch 100' comprises an electrode unit 10', an adapter plate 20' detachably connected to the electrode unit 10', a wire 30' electrically connected to the adapter plate 20', a backing 40' adhered to the corresponding parts of the electrode unit 10' and the adapter plate 20', a support 50' surrounding the corresponding part of the electrode unit 10' and adhered to the backing 40', and an adhesive 60' covering the support 50' and the corresponding part of the electrode unit 10' and adhered to the body surface skin corresponding to the patient's tumor site. The electrode patch 100' is adhered to the body surface corresponding to the patient's tumor site through the backing 40', and applies an alternating electric field to the patient's tumor site through the electrode unit 10' detachably connected to the adapter plate 20' to interfere with or prevent the mitosis of the patient's tumor cells, thereby achieving the purpose of treating the tumor.

Compared with the electrode patch 100 of the first embodiment, the electrode patch 100' of this embodiment also includes an adapter plate 20', an electrode unit 10' detachably assembled on the adapter plate 20', a wire 30' welded to the adapter plate 20, a backing 40' adhered to the corresponding parts of the electrode unit 10' and the adapter plate 20', a support member 50' surrounding the corresponding part of the electrode unit 10' and adhered to the backing 40', and an adhesive member 60' covering the support member 50' and the corresponding part of the electrode unit 10' and adhering to the surface skin of the patient corresponding to the tumor site. The electrode unit 10' of the electrode patch 100' of the present embodiment has the same structure as the electrode unit 10 of the electrode patch 100 of the first embodiment, and also includes an insulating plate 13' and a dielectric element 12' disposed on opposite sides of the flexible board substrate 11', and a male seat 15' located on the same side of the flexible board substrate 11' as the dielectric element 12' and disposed on opposite ends of the flexible board substrate 11' with the dielectric element 12'. The difference between the electrode patch 100' of the present embodiment and the electrode patch 100 of the first embodiment is that the electrode patch 100' only includes one electrode unit 10' that is detachably plugged into the adapter plate 20', and the shapes of the adapter plate 20' and the backing 40' are different depending on the number of plugged electrode units 10'.

9A to 11B , the adapter plate 20' also includes a main body 28' plugged into the electrode unit 10', a female seat 25' disposed on the main body 28', and a wiring portion 27' extending laterally from the main body 28'. The male seat 15' of the electrode unit 10' is plugged into the female seat 25' to achieve electrical connection between the electrode unit 10' and the adapter plate 20'. The wiring portion 27' is welded to the wire 30' to achieve electrical connection between the adapter plate 20' and the wire 30'. The main body 28' has only one trunk 21', and the female seat 25' is disposed on the trunk 21' and is located at opposite ends of the trunk 21' with the wiring portion 27'. The trunk 21' has only one set of female seats 25' and female seats 25'. The third pad 23' is welded to the socket 25'. The third pad 23' includes a third pad 23B' for transmitting a temperature signal, a third pad 23A' for transmitting a ground signal, and a plurality of third pads 23C' for transmitting an alternating current signal. The plurality of third pads 23C' are all electrically connected to a transmission AC signal line. In this embodiment, there are six third pads 23', of which one third pad 23B' for transmitting a temperature signal, one third pad 23A' for transmitting a ground signal, and four third pads 23C' for transmitting an alternating current signal. There is only one mother socket 25'. Both side surfaces of the wiring portion 27' are provided with a plurality of fourth pads 24' welded to the wire 30'. The fourth pad 24' includes a fourth pad 24A' for transmitting a ground signal, a fourth pad 24B' for transmitting a temperature signal, a fourth pad 24C' for transmitting an alternating current signal, a plurality of fourth pads 24D', and a fourth pad 24E' for shielding. The fourth soldering pads 24D' are respectively arranged on opposite sides of the wiring portion 27' of the adapter board 20'. In the present embodiment, there are seven fourth soldering pads 24D', two of which are arranged on the same side of the adapter board 20', and the other five are arranged on the other side of the adapter board 20'. The two fourth soldering pads 24D' located on the same side are respectively arranged on one side of the end of the wiring portion 27' in a manner of spacing apart the three fourth soldering pads 24A', 24B', and 24C' located on the same side. The fourth soldering pad 24D' can be welded to the corresponding wire core of the wire 30', so as to make the welding between the wiring portion 27' and the wire 30' more secure, so as to avoid damage to the adapter board 20' and inability to transmit signals due to disconnection of the welding portion between the wiring portion 27' and the wire 30' when the wire 30' is pulled by force.

Three second conductive traces 26' are embedded in the adapter board 20'. None of the fourth pads 24D' are electrically connected to the second conductive traces 26'. The three second conductive traces 26' are respectively a second ground line 26A', a second signal line 26B' and a second AC line 26C'. One end of the second ground line 26A' is connected to the third pad 23A', and the other end is connected to a fourth pad 24A' for transmitting a ground signal. One end of the second signal line 26B' is connected to the third pad 23B', and the other end is connected to the fourth pad 24B' for transmitting a temperature signal. One end of the second AC line 26C' is connected in series to the remaining four third pads 23C', and the other end is connected to a fourth pad 24C' for transmitting an alternating current signal. The number of the fourth pads 24' in this embodiment is greater than the number of the fourth pads 24' connected to the second conductive traces 26. The number of the fourth pads 24' on each side of the connection portion 27' is 5, and the fourth pads 24' on one side include the fourth pads 24' electrically connected to the second ground line 26A', the second signal line 26B' and the second AC line 26C' respectively. Solder pads 24A', 24B', 24C' and two fourth solder pads 24D' that are not electrically connected to the second ground line 26A', the second signal line 26B', and the second AC line 26C'. The five fourth solder pads 24' located on the other side of the wiring portion 27' are all fourth solder pads 24D', none of which are electrically connected to the second conductive trace 26'. The fourth solder pads 24' electrically connected to the second conductive trace 26' are all conductive pads 24A', 24B', 24C', and the fourth solder pads 24' that are not electrically connected to the second conductive trace 26' are all virtual pads 24D'. The three conductive pads 24A', 24B', 24C' and the third solder pads 23A', 23B', 23C' are all located on the same side of the adapter board 20'. The fourth solder pad 24E' for shielding is a shielding pad, which is also electrically connected to the second ground line 26A'.

The wire 30' has 10 cores (not shown), of which 3 cores (not shown) are respectively welded to the 3 conductive pads 24A', 24B', 24C' in the fourth pad 24' of the wiring portion 27', and the remaining 7 cores (not shown) are respectively welded to the 7 virtual pads 24D' in a one-to-one correspondence. The wire 30' is provided with a plug 32' at the end away from the wiring portion 27'. The plug 32' can also be connected to an adapter wire 33'. The number of cores (not shown) of the adapter wire 33' is consistent with the number of cores (not shown) of the wire 30', and they correspond one to one. The heat shrink tubing 31' is wrapped around the outer periphery of the welding point between the wire 30' and the wiring portion 27' of the adapter board 20'.

The backing 40' is generally in the shape of a square sheet, and at least two lugs 42' are provided on its edge, so that the operator can hold the electrode patch 100' and apply the electrode patch 100' to the body surface corresponding to the tumor site of the patient. The side of the electrode unit 10' away from the dielectric element 12' is adhered to the backing 40'. The backing 40' is also adhered to the corresponding parts of the adapter plate 20' and the heat shrink sleeve 31'. The heat shrink sleeve 31 can also be covered on the periphery of the male seat 15' and the female seat 25' for disassembly and assembly.

The support member 50' is generally in the shape of a square sheet, and a through hole 51' is provided in the middle thereof. The through hole 51' is similar to the first through hole 51A of the embodiment, and is used to accommodate the dielectric element 12' of the electrode unit 10'. As in the first embodiment, the support member 50' is generally flush with the surface of the side of the dielectric element 12' of the electrode unit 10' away from the backing 40'.

The adhesive member 60' is generally in the shape of a square sheet, covering the support member 50' and the surface of the dielectric element 12' of the electrode unit 10' away from the backing 40'. The size of the adhesive member 60' is generally the same as that of the support member 50'. The 50' is the same size.

The electrode patches 100, 100' of the tumor electric field therapy device 1000 of the present invention are composed of at least one electrode unit 10, 10' and an adapter plate 20, 20' that are detachably connected to realize the detachable replacement of failed electrode units 10, 10' on the electrode patches 100, 100', or the detachable replacement of failed adapter plates 20, 20' on the electrode patches 100, 100', thereby reducing the loss of the entire electrode patches 100, 100', reducing the yield loss of the electrode patches 100, 100', and avoiding the scrapping and waste of the entire electrode patches 100, 100' when one of the electrode units 10, 10' and the adapter plates 20, 20' is damaged. In addition, the electrode patch 100 of the present application cooperates with multiple female sockets 25 set on the adapter plate 20 and the electrode units 10 that can be plugged into the female sockets 25. According to the size and location of the tumor, a suitable number of electrode units 10 can be freely selected to be plugged into the adapter plate 20', thereby ensuring that the coverage area of the electrode patch 100 and the strength of the applied alternating electric field reach the electric field strength required for tumor treatment.

FIG. 12 is a method for manufacturing the electrode patch 100, 100' of the present invention shown in FIG. 1 to FIG. 11, which comprises the following steps:

S11, providing an adapter board 20, 20', wherein the adapter board 20, 20' has at least one set of third pads 23, 23' and a wiring portion 27, 27';

S12, providing at least one female socket 25, 25', and welding the female sockets 25, 25' to the corresponding third soldering pads 23, 23' of the adapter plates 20, 20' respectively;

S13, providing a wire 30, 30', and assembling the wire 30, 30' on the connection parts 27, 27' of the adapter plates 20, 20';

S14, providing a heat shrinkable tube 31, 31', and covering the heat shrinkable tube 31, 31' at the connection between the adapter plate 20, 20' and the wire 30, 30';

S15, providing at least one electrode unit 10, 10' detachably connected to the adapter plate 20, 20', and clamping the electrode unit 10, 10' to the female socket 25, 25' on the adapter plate 20, 20';

S16, provide a backing 40, 40', and adhere the corresponding part of the surface of one side of the adapter plate 20, 20' on which the female seat 25, 25' is set after the above steps and the surface of the electrode unit 10, 10' on the same side to the backing Lining 40, 40'.

In the above step S11, the adapter board 20, 20' further comprises the body 28, 28' of the above first and second embodiments. At least one set of third pads 23, 23' is distributed on the body 28, 28'. The body 28, 28' is connected to the wiring portion 27, 27'.

In the above step S13, the wires 30, 30' can also be plugged into the adapter wires 33, 33' of the above-mentioned first embodiment and second embodiment.

The manufacturing method of the electrode patch 100, 100' of the present invention further comprises the following steps:

S17, providing a support member 50, 50', and bonding the support member 50, 50' to the backing 40, 40' so as to surround the corresponding parts of the electrode units 10, 10';

S18, providing an adhesive member 60, 60', and adhering the adhesive member 60, 60' to the surface of the corresponding part of the support member 50, 50' and the electrode unit 10, 10' away from the backing 40, 40';

S19, providing a release paper 70, and covering the release paper 70 on the surface of the backing 40, 40' and the adhesive member 60, 60' close to the patient's skin.

In the above step S17 , the support member 50 , 50 ′ has at least one through hole 51 , 51 ′ disposed therethrough to receive the corresponding portion of the corresponding electrode unit 10 , 10 ′.

Referring to FIG. 13 , the manufacturing method of the electrode unit 10, 10' of the electrode patch 100, 100' of the present invention comprises the following steps:

S21, providing a flexible board substrate 11, wherein one end of the flexible board substrate 11 has a plurality of conductive pads 111 arranged in an interval shape and two first pads 112 located in an area surrounded by the plurality of conductive pads 111, and the other end of the flexible board substrate 11 has a plurality of second pads 113;

S22, providing a support plate 13, and assembling the support plate 13 on the flexible board substrate 11 in a one-to-one correspondence with the plurality of conductive plates 111, wherein the support plate 13 and the conductive plates 111 are located on opposite sides of the flexible board substrate 11;

S23, providing a temperature sensor 14, and welding the temperature sensor 14 to the two first welding pads 112 up;

S24, providing a dielectric element 12 having an opening 121, and welding the dielectric element 12 to the plurality of conductive plates 111 in such a manner that the openings of the dielectric element 12 accommodate corresponding temperature sensors, wherein the temperature sensors 14 are accommodated in the openings 121 of the dielectric element 12;

S25 , providing a male socket 15 , and welding the male socket 15 to the plurality of second solder pads 113 .

In step S21, the conductive pad 111, the first pad 112 and the second pad 113 are all disposed on the same side surface of the flexible board substrate 11. The conductive pad 111 and the second pad 113 are located at opposite ends of the flexible board substrate 11, respectively.

The above is only a preferred implementation mode of the present application and is not intended to limit the present application. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present application should be included in the scope of protection of the present application.

Claims (67)

An electrode patch for electric field therapy of tumors, characterized in that it includes at least one electrode unit, an adapter board formed by a flexible circuit board and a backing, wherein the electrode unit and the adapter board are partially adhered to the backing, the electrode unit includes a flexible board substrate, the flexible board substrate is provided with a male seat, the adapter board is provided with at least one female seat, and the male seat and the female seat are plugged together to make the electrode unit and the adapter board detachably electrically connected. The electrode patch according to claim 1 is characterized in that each of the electrode units includes a support plate and a dielectric element respectively arranged on both sides of the flexible board substrate, and the male seat is arranged on the flexible board substrate and is located on the same side surface of the flexible board substrate as the dielectric element. The electrode patch according to claim 2 is characterized in that the dielectric element and the male seat are respectively located at opposite ends of the flexible board substrate, and the dielectric element and the support plate are both located at the same end of the flexible board substrate. The electrode patch according to claim 2 is characterized in that the electrode unit also includes a temperature sensor disposed on the flexible board substrate and located on the same side as the dielectric element. The electrode patch according to claim 4 is characterized in that the dielectric element has a through opening, and the temperature sensor is accommodated in the opening of the dielectric element. The electrode patch according to claim 1 is characterized in that the electrode unit and the adapter plate are adhered to the backing in a partially overlapping manner, and the male seat and the corresponding female seat are located at the overlapping position. The electrode patch according to claim 1 is characterized in that the adapter plate includes a main body and a wiring portion connected to the main body, at least one female socket of the adapter plate is arranged on the main body, and the wiring portion is located at one end of the main body. The electrode patch according to claim 7 is characterized in that the main body has a trunk, and the at least one female seat is located on the trunk. The electrode patch according to claim 8 is characterized in that the trunk of the body is provided with At least one hollow hole is arranged in a through shape, and the hollow hole is arranged corresponding to the corresponding female seat. The electrode patch according to claim 9 is characterized in that the hollow hole allows the corresponding dielectric element of the electrode unit to pass through, and the dielectric element of the electrode unit is exposed to the side of the adapter plate away from the mother seat when the electrode unit is assembled on the adapter plate. The electrode patch according to claim 8 is characterized in that the main body also includes a plurality of branches located on both sides of the main trunk, and the mother seat is provided on the branches. The electrode patch according to claim 11 is characterized in that there is a gap between two adjacent branches located on the same side of the main trunk to allow the dielectric elements of the corresponding electrode units to pass through, and the dielectric elements of the electrode units are exposed to the side of the adapter plate away from the mother seat after passing through the gap. The electrode patch according to claim 12 is characterized in that the electrode patch also includes a wire electrically connected to the wiring portion of the adapter board, one end of the wire is electrically connected to the wiring portion of the adapter board, and the other end is provided with a plug. The electrode patch according to claim 13 is characterized in that a circle of heat shrink tubing is also provided around the periphery of the connection between the wire and the wiring portion. The electrode patch according to claim 13 is characterized in that the plug of the wire can be detachably plugged into a switching wire. The electrode patch according to claim 1 is characterized in that the backing is arranged in a sheet shape and has at least one through hole corresponding to the electrode unit and arranged in a through shape, and the through hole of the backing allows the corresponding part of the electrode unit to be exposed on the side surface of the backing away from the adapter plate. The electrode patch according to claim 16 is characterized in that the electrode patch also includes a support member that is arranged around the corresponding part of the electrode unit and adhered to the backing, and an adhesive member that covers the support member and the corresponding part of the electrode unit and adheres to the surface skin of the patient corresponding to the tumor site. The electrode patch according to claim 17 is characterized in that the support member has at least one through-hole arranged in a penetrating shape. The electrode patch according to claim 18 is characterized in that the perforation includes a first perforation corresponding to the corresponding electrode unit and accommodating a corresponding portion of the corresponding electrode unit. The electrode patch according to claim 19 is characterized in that the perforation further includes a second perforation located between the plurality of first perforations and opposite to the adapter plate. The electrode patch according to claim 17, characterized in that the electrode patch also includes at least one release paper located on a side of the adhesive member away from the backing and covering the adhesive member and the backing. The electrode patch according to claim 1 is characterized in that the electrode unit includes a flexible board substrate and a dielectric element and a male socket respectively arranged at opposite ends of the same side of the flexible board substrate, and a first AC line electrically connected to both the dielectric element and the male socket is embedded in the flexible board substrate, and the first AC line is arranged in a ring shape along the periphery of the flexible board substrate and forms two sections of lines electrically connecting the male socket and the dielectric element. The electrode patch according to claim 22 is characterized in that the dielectric element has an opening arranged in a through shape. The electrode patch according to claim 23 is characterized in that the electrode unit also includes a temperature sensor arranged on the flexible board substrate, and the temperature sensor is accommodated in the opening of the dielectric element and is located on the same side of the flexible board substrate as the dielectric element. The electrode patch according to claim 24 is characterized in that the temperature sensor has a ground terminal and a signal terminal. The electrode patch according to claim 25 is characterized in that a first grounding wire electrically connected to the ground end of the temperature sensor and the male socket and a first signal wire electrically connected to the signal end of the temperature sensor and the male socket and transmitting a temperature signal are also embedded in the flexible board substrate. The electrode patch according to claim 26 is characterized in that the flexible board substrate is further provided with a plurality of conductive pads arranged in an interval shape and welded to the dielectric element, two first solder pads respectively welded to the ground terminal and the signal terminal of the temperature sensor, and a plurality of conductive pads respectively welded to the male seat. Solder the second pad. The electrode patch according to claim 27 is characterized in that the conductive pad and the first pad are located at the same end of the flexible board substrate, the second pad is located at the other end of the flexible board substrate, and two of the first pads are located in the middle position surrounded by multiple conductive pads. The electrode patch according to claim 27 is characterized in that the first pad welded to the ground end of the temperature sensor is connected to the first ground wire, and the first pad welded to the signal end of the temperature sensor is connected to the first signal wire. The electrode patch according to claim 27 is characterized in that there are multiple second pads, and the number is at least 4. The electrode patch according to claim 30 is characterized in that two of the multiple second pads are respectively connected to the first ground line, the first signal line and two lines of the first AC line, and the remaining second pads of the multiple second pads are all commonly connected in series to the remaining one line of the first ground line, the first signal line and the first AC line. The electrode patch according to claim 31 is characterized in that two of the plurality of second pads are respectively connected to the first ground line and the first signal line, and the remaining second pads of the plurality of second pads are all commonly connected in series to the first AC line. The electrode patch according to claim 22 is characterized in that the electrode unit also includes a support plate, and the support plate and the dielectric element are respectively located on opposite sides of the flexible board substrate and correspond one to one along the thickness direction. The electrode patch according to claim 22 is characterized in that a reinforcing plate is attached to the surface of the flexible board substrate facing away from the male seat, and the reinforcing plate and the male seat are both located at one end of the flexible board substrate. The electrode patch according to claim 1 is characterized in that the electrode unit includes a flexible board substrate and a dielectric element and a male socket respectively arranged at opposite ends of the flexible board substrate, and the male socket is electrically connected to the dielectric element through two sections of the flexible board substrate. The electrode patch according to claim 35, characterized in that the flexible board substrate Three first conductive traces are embedded therein, and the three first conductive traces are respectively a first grounding line, a first signal line, and a first AC line arranged in a ring shape. The electrode patch according to claim 36 is characterized in that the two sections of the line together constitute the first AC line, and the male socket is electrically connected to the dielectric element through the two sections of the first AC line. The electrode patch according to claim 37 is characterized in that the first AC line is arranged in a ring shape along the periphery of the flexible board substrate and is in a two-segment structure with the head and tail electrically connected at the position where the male socket is set on the flexible board substrate. The electrode patch according to claim 36 is characterized in that the electrode unit also includes a temperature sensor arranged on the flexible board substrate, the temperature sensor is located on the same side as the dielectric element and has a ground terminal and a signal terminal. The electrode patch according to claim 39 is characterized in that the dielectric element has an opening arranged in a through shape, and the temperature sensor is accommodated in the opening. The electrode patch according to claim 39 is characterized in that the first ground wire is electrically connected to the ground end of the temperature sensor and the male socket, and the first signal wire is electrically connected to the signal end of the temperature sensor and the male socket and transmits a temperature signal. The electrode patch according to claim 41 is characterized in that the first ground wire and the first signal wire are both located within the area enclosed by the first AC wire. The electrode patch according to claim 35 is characterized in that the electrode unit also includes a support plate, the support plate is located on a side of the flexible board substrate away from the dielectric element, and the support plate corresponds to the dielectric element one by one along the thickness direction. The electrode patch according to claim 35 is characterized in that a reinforcement plate is attached to the surface of the flexible board substrate facing away from the male seat, and the reinforcement plate and the male seat are located at the same end of the flexible board substrate. The electrode patch according to any one of claims 1 to 44 is characterized in that the adapter plate includes at least one female socket, and the male socket of the electrode unit is detachably connected to a corresponding female socket of the adapter plate. The electrode patch according to claim 45 is characterized in that it also includes a wire electrically connected to the adapter plate, a backing adhered to the electrode unit and the corresponding parts of the adapter plate, a support member surrounding the corresponding parts of the electrode unit and adhered to the backing, and an adhesive member covering the support member and the corresponding parts of the electrode unit and adhered to the surface skin of the patient corresponding to the tumor site. An electrode patch for electric field therapy of tumors, characterized in that it includes multiple electrode units, an adapter board formed by a flexible circuit board and a backing, the multiple electrode units and the adapter board are all adhered to the backing, the adapter board partially overlaps with each of the electrode units and forms a detachable electrical plug connection with each of the electrode units at the overlapping portion, a second AC line for transmitting alternating electrical signals is embedded in the adapter board, and the multiple electrode units are connected in parallel to the second AC line of the adapter board. The electrode patch according to claim 47 is characterized in that each of the electrode units includes a flexible board substrate, a support plate and a dielectric element respectively arranged on both sides of the flexible board substrate, and a male seat arranged on the flexible board substrate, and the dielectric element and the male seat are electrically connected to the flexible board substrate and are respectively located at opposite ends of the flexible board substrate. The electrode patch according to claim 48 is characterized in that the adapter plate is provided with a plurality of female sockets detachably connected to the male sockets corresponding to the electrode units, and the plurality of female sockets are all connected in parallel to the second AC line. The electrode patch according to claim 49 is characterized in that the corresponding dielectric elements of the plurality of electrode units are connected in parallel to the second AC line of the adapter board through their male sockets provided on the flexible board substrate and connected to the female sockets of the adapter board. The electrode patch according to claim 49 is characterized in that each of the electrode units includes a temperature sensor electrically connected to the flexible board substrate, the temperature sensor is located on the same side as the dielectric element and has a ground terminal and a signal terminal. The electrode patch according to claim 51 is characterized in that the dielectric element is provided with a through opening, and the temperature sensor is accommodated in the opening. The electrode patch according to claim 51 is characterized in that a second ground wire for transmitting a ground signal to the temperature sensor and multiple second signal wires for transmitting the temperature signals of the temperature sensors in parallel are embedded inside the adapter board. The electrode patch according to claim 53 is characterized in that the ground terminals of the corresponding temperature sensors of the multiple electrode units are connected in parallel to the second ground line of the adapter board through the male socket provided on the flexible board substrate and the corresponding female socket of the adapter board, and the signal terminals of the corresponding temperature sensors of the multiple electrode units are electrically connected to the corresponding second signal line of the adapter board through the male socket provided on the flexible board substrate and the corresponding female socket of the adapter board. The electrode patch according to claim 53 is characterized in that the second AC line and the second ground line are both arranged in a tree-like wiring arrangement. The electrode patch according to claim 49 is characterized in that the adapter plate has a main body that can be detachably connected to a plurality of the electrode units and a wiring portion, and the plurality of female sockets are arranged on the main body in an interval shape. The electrode patch according to claim 56 is characterized in that the main body also has a trunk and at least one branch, and the multiple mother seats are arranged on the trunk and the branch in an interval manner. The electrode patch according to claim 56 is characterized in that it also includes a wire welded to the wiring portion. The electrode patch according to claim 58 is characterized in that a heat shrink tube is provided around the welding point between the wiring portion and the wire. The electrode patch according to claim 58 is characterized in that a plurality of fourth pads are provided on both side surfaces of the wiring portion, and the plurality of fourth pads are all welded to the wire, and the plurality of fourth pads include a plurality of conductive pads electrically connected to the corresponding second AC line, the second ground line and the second signal line, and a plurality of virtual pads that are not electrically connected to the second AC line, the second ground line and the second signal line. The electrode patch according to claim 49 is characterized in that the dielectric elements of the plurality of electrode units are all exposed to a side of the adapter plate away from the mother seat. The electrode patch according to claim 47 is characterized in that it also includes a support member that surrounds the corresponding parts of the multiple electrode units and is adhered to the backing, and an adhesive member that covers the support member and the corresponding parts of the multiple electrode units and is adhered to the surface skin of the patient corresponding to the tumor site. A method for manufacturing an electrode patch according to any one of claims 1 to 21, characterized in that it comprises the following steps: S11, providing an adapter board, wherein the adapter board has at least one set of third pads and a wiring portion; S12, providing at least one female socket, and welding the female sockets to corresponding third pads of the adapter board respectively; S13, providing a wire, and placing the wire group at the connection part of the adapter board; S14, providing a heat shrink tubing, and covering the heat shrink tubing at the connection between the adapter plate and the wire; S15, providing at least one electrode unit detachably connected to the adapter plate, and clamping the electrode unit to the female socket on the adapter plate; S16, providing a backing, and gluing the corresponding part of the surface of one side of the adapter plate on which the mother seat is set after the above steps and the surface of the electrode unit on the same side onto the backing. The method for manufacturing an electrode patch according to claim 63, characterized in that after step S16, the method further comprises the following steps: S17, providing a support member, and bonding the support member to the backing so as to surround the corresponding part of the electrode unit; S18, providing an adhesive member, and adhering the adhesive member to the surface of the supporting member and the corresponding part of the electrode unit away from the backing; S19. Provide a release paper and cover the backing and the surface of the adhesive piece close to the patient's skin with the release paper. The method for manufacturing an electrode patch according to claim 63, characterized in that the method for manufacturing the electrode unit comprises the following steps: S21, providing a flexible board substrate, wherein one end of the flexible board substrate has a plurality of conductive pads arranged in an interval shape and two first pads located in an area surrounded by the plurality of conductive pads, and the other end of the flexible board substrate has a plurality of second pads; S22, providing a support plate, and assembling the support plate on the flexible board substrate in a one-to-one correspondence with the plurality of conductive plates, wherein the support plate and the conductive plates are located on opposite sides of the flexible board substrate; S23, providing a temperature sensor, and welding the temperature sensor to the two first welding pads; S24, providing a dielectric element with an opening, and welding the dielectric element to the plurality of conductive plates in such a manner that the opening of the dielectric element accommodates the corresponding temperature sensors; S25, providing a male socket, and welding the male socket to the plurality of second welding pads. A tumor electric field therapy device, characterized in that it comprises an electric field generator and at least one pair of electrode patches as described in any one of claims 1 to 62 connected to the electric field generator. The tumor electric field therapy device according to claim 66 is characterized in that it also includes an adapter electrically connected between the electrode patch and the electric field generator.