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WO2024186663A1 - Formules de produit cosmétique utilisées pour administration d'une grande diversité de composants actifs - Google Patents

Formules de produit cosmétique utilisées pour administration d'une grande diversité de composants actifs Download PDF

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Publication number
WO2024186663A1
WO2024186663A1 PCT/US2024/018170 US2024018170W WO2024186663A1 WO 2024186663 A1 WO2024186663 A1 WO 2024186663A1 US 2024018170 W US2024018170 W US 2024018170W WO 2024186663 A1 WO2024186663 A1 WO 2024186663A1
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Prior art keywords
cosmetic formula
range
cosmetic
formula
mixture
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English (en)
Inventor
Alice BURZAVA
Karine BARBE
Muriel Pujos
Karine Julien
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Coty Inc
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Coty Inc
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Priority to CN202480025043.7A priority Critical patent/CN121099981A/zh
Publication of WO2024186663A1 publication Critical patent/WO2024186663A1/fr
Anticipated expiration legal-status Critical
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/99—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from microorganisms other than algae or fungi, e.g. protozoa or bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/31—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/737—Galactomannans, e.g. guar; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations

Definitions

  • Cosmetic formulations can be used to deliver any variety of beneficial effects to a user. Often the beneficial effect is provided by an active component. The ability to increase the diversity and amount of active component can increase the utility of the cosmetic formulation.
  • the cosmetic formula includes a gel mixture in a range of from about 0.1 wt% to about 2 wt% of the cosmetic formula.
  • the gel mixture includes sphingomas ferment extract; xanthan gum; and a mixture of hydroxy ethyl acrylate/sodium acryloyldimethyl taurate copolymer & sorbitan isostearate.
  • the cosmetic formula also includes a surfactant in a range of from about 0.1 wt% to about 2 wt% of the cosmetic formula and comprising sodium stearoyl glutamate.
  • the cosmetic formula also includes an oil phase in a range of from about 2 wt% to about 15 wt% of the cosmetic formula.
  • the oil phase includes caprylic capric triglyceride; a C15-19 alkane.
  • the cosmetic formula further includes an active component.
  • a pH of the cosmetic formula is in a range of from about 5 to about 7.
  • a viscosity of the cosmetic formula is in a range of from about 1500 cPs to about 5000 cPs.
  • the cosmetic formula is sufficiently stable for at least 2 months at a temperature of about 45 °C.
  • the acts can be carried out in any order without departing from the principles of the invention, except when a temporal or operational sequence is explicitly recited. Furthermore, specified acts can be carried out concurrently unless explicit claim language recites that they be carried out separately. For example, a claimed act of doing X and a claimed act of doing Y can be conducted simultaneously within a single operation, and the resulting process will fall within the literal scope of the claimed process.
  • substantially refers to a majority of, or mostly, as in at least about 50%, 60%, 70%, 80%, 90%, 95%, 96%, 97%, 98%, 99%, 99.5%, 99.9%, 99.99%, or at least about 99.999% or more, or 100%.
  • substantially free of can mean having none or having a trivial amount of, such that the amount of material present does not affect the material properties of the composition including the material, such that about 0 wt% to about 5 wt% of the composition is the material, or about 0 wt% to about 1 wt%, or about 5 wt% or less, or less than or equal to about 4.5 wt%, 4, 3.5, 3, 2.5, 2, 1.5, 1, 0.9, 0.8, 0.7, 0.6, 0.5, 0.4, 0.3, 0.2, 0.1, 0.01, or about 0.001 wt% or less, or about 0 wt%.
  • the cosmetic formula can be omnipotent in that it is capable of having one or more beneficial effects on a user’s skin.
  • the omnipotent cosmetic formula can take the form of a serum. Examples of uses for the cosmetic formula include use for skin fine lines reduction, improving skin firmness, evening skin tone, strengthening skin barrier, hydrating skin, enhancing skin natural radiance, or a combination thereof.
  • the properties of the cosmetic formula are a function of its components. Specifically, the ability to locate an active component in an oil phase of the formula.
  • the gel mixture can give the cosmetic formula sufficient properties relating to viscosity, feel/texture, and the like.
  • the texture of the formulation is similar to a serum and can have a substantially translucent appearance.
  • the gel mixture as a whole is in a range off from about 0.1 wt% to about 2 wt% of the cosmetic formula, about 0.3 wt% to about 1 wt%, less than, equal to, or greater than about 0.1 wt%, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, or about 2 wt%.
  • the gel mixture includes sphingomas ferment extract; xanthan gum; and a mixture of hydroxy ethyl acrylate/sodium acryloyldimethyl taurate copolymer & sorbitan isostearate.
  • sphingomas ferment extract is in a range of from about 0.05 wt% to about 0.40 wt% of the cosmetic formula, about 0.15 wt% to about 0.30 wt%, less than, equal to, or greater than about 0.05 wt%, 0.10, 0.15, 0.20, 0.25, 0.30, 0.35, or about 0.40 wt%.
  • xanthan gum is in a range of from about 0.05 wt% to about 0.30 wt% of the cosmetic formula, 0.10 wt% to about 0.20 wt%, less than, equal to, or greater than about 0.05 wt%, 0.10, 0.15, 0.20, 0.25, or about 0.30 wt%.
  • the mixture of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer & sorbitan isostearate is in a range of from about 0.15 wt% to about 0.50 wt% of the cosmetic formula, about 0.20 wt% to about 0.40 wt%, less than, equal to, or greater than about 0.15 wt%, 0.20, 0.25, 0.30, 0.35, 0.40, 0.45, or about 0.50 wt%.
  • the cosmetic formulation can include any number of suitable surfactants.
  • the surfactant can help to tune the feel, texture, and spreadability of the cosmetic formulation.
  • An example of a suitable surfactant can include sodium stearoyl glutamate.
  • the surfactant can be in a range of from about 0.1 wt% to about 2 wt% of the cosmetic formulation, about 0.1 wt% to about 1.5 wt%, less than, equal to, or greater than about 0.1 wt%, 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, 1.9, or about 2 wt%.
  • the surfactant can be a single surfactant or can be a mixture of many other suitable surfactants in addition to sodium stearoyl glutamate.
  • the surfactant can include nonionic surfactants.
  • Suitable nonionic surfactants are disclosed in U.S. Pat. No. 3,929,678, Laughlin et al., issued Dec. 30, 1975, and U.S. Pat. No. 4,285,841, Barrat et al, issued Aug. 25, 1981.
  • Exemplary, non-limiting classes of useful nonionic surfactants include Cs-Cis alkyl ethoxylates, with about 1-22 ethylene oxide units, including the so-called narrow peaked alkyl ethoxylates and Ce-Cn alkyl phenol alkoxylates, particularly ethoxylates and mixed ethoxylates/propoxylates, alkyl dialkyl amine oxides, alkanoyl glucose amides, and mixtures thereof.
  • Other useful nonionic surfactants are polyethylene, polypropylene, and polybutylene oxide condensates of alkyl phenols.
  • nonionic surfactants of this type include Igepal® CO-630, marketed by the GAF Corporation; and Triton® X45, X-l 14, X- 100, and X-l 02, all marketed by the Rohm & Haas Company. These compounds are commonly referred to as alkyl phenol alkoxylates, preferably alkyl phenol ethoxylates. Further useful nonionic surfactants are the condensation products of aliphatic alcohols with from about 1 to about 25 moles of ethylene oxide. The alkyl chain of the aliphatic alcohol can either be straight or branched, primary or secondary, and generally contains from about 8 to about 22 carbon atoms.
  • nonionic surfactants of this type include Tergitol® 15-S-9 (the condensation product of C11-C15 linear secondary alcohol with 9 moles ethylene oxide), Tergitol® 24-L-6 NMW (the condensation product of C12- C14 primary alcohol with 6 moles ethylene oxide with a narrow molecular weight distribution), both marketed by The Dow Chemical Corporation; Neodol® 45-9 (the condensation product of C14-C15 linear alcohol with 9 moles of ethylene oxide), Neodol® 23- 6.5 (the condensation product of C12-C13 linear alcohol with 6.5 moles of ethylene oxide), Neodol® 45-7 (the condensation product of C14-C15 linear alcohol with 7 moles of ethylene oxide), Neodol® 45-4 (the condensation product of C14-C15 linear alcohol with 4 moles of ethylene oxide), marketed by Shell Chemical Company, and Kyro® EOB (the condensation product of C13-C15 alcohol with 9 moles ethylene oxide), marketed by The Procter & Gamble Company.
  • nonionic surfactants include Dobanol 91-8® marketed by Shell Chemical Co. and Genapol UD-080® marketed by Hoechst. This category of nonionic surfactant is referred to generally as “alkyl ethoxylates.”
  • Other useful nonionic surfactants are the condensation products of ethylene oxide with a hydrophobic base formed by the condensation of propylene oxide with propylene glycol. Examples of compounds of this type include certain of the commercially-available Pluronic® surfactants, marketed by BASF. Further useful surfactants are the condensation products of ethylene oxide with the product resulting from the reaction of propylene oxide and ethylenediamine.
  • nonionic surfactants examples include certain of the commercially available Tetronic® compounds, marketed by BASF.
  • Semi-polar nonionic surfactants are a special category of nonionic surfactants which include water-soluble amine oxides. These amine oxide surfactants in particular include Cio-Cis alkyl dimethyl amine oxides and Cs-Cn alkoxy ethyl dihydroxy ethyl amine oxides.
  • Other nonionic surfactants are alkylpolysaccharides. Any reducing saccharide containing 5 or 6 carbon atoms can be used, e.g., glucose, galactose and galactosyl moieties can be substituted for the glucosyl moieties.
  • Fatty acid amide surfactants, C12-C18 betaines and sulfobetaines (sultaines) are also knows surfactants.
  • Further useful surfactants are amine oxide surfactants.
  • Commercially available amine oxides are the solid, dihydrate ADMOX 16 and ADMOX 18, ADMOX 12 and especially ADMOX 14 from Ethyl Corp.
  • Other surfactants include dodecyidimethylamine oxide dihydrate, hexadecyidimethylamine oxide dihydrate, octadecyidimethylamine oxide dihydrate, hexadecyltris(ethyleneoxy)dimethyl-amine oxide, tetradecyidimethylamine oxide dihydrate, and mixtures thereof.
  • biodegradably branched surfactants are more fully disclosed in WO98/23712 A published Jun. 4, 1998; WO97/38957 A published Oct. 23, 1997; WO97/38956 A published Oct. 23, 1997; WO97/39091 A published Oct. 23, 1997; WO97/39089 A published Oct. 23, 1997; WO97/39088 A published Oct. 23, 1997;
  • Specifically useful surfactants can include a polyglyceryl fatty acid ester, polyglyceryl-3 diisostearate, polyglyceryl-4 isostearate, polyglyceryl-3 cocoate, polyglyceryl- 6 Ricinoleate, polyglyceryl-3 stearate polyglyceryl- 10 stearate, polyglyceryl- 10 oleate, polyglyceryl-4 diisostearate/ polyhydroxy stearate/sebacate, polyglyceryl-2 dipolyhydroxystearate, polyglyceryl-3 poliricinoleate, polyglyceryl-6 stearate (and) polyglyceryl 6-behenate, sorbitan esters, sucrose esters, alkyl polyglycosides, fatty acid glucamides, or a mixture thereof.
  • the polyglyceryl fatty acid ester can include a mixture of polyglyceryl-4 laurate/sebacate; polyglyceryl-6 caprylate/caprate; and water.
  • the polyglyceryl fatty acid ester can alternatively or additionally include a mixture of polyglyceryl-4 laurate/sebacate, polyglyceryl-4 caprylate/caprate; and water.
  • the polyglyceryl fatty acid ester can alternatively or additionally include polyglyceryl-4 caprate.
  • ester surfactants can include a mixture of caprylic and capryc triglyceride, PEG-7 glyceryl cocoate, isosteryl neopentanoate, ethylhexyl palmitate, diethylhexyl adipate, diethylhexyl succinate, isotearyl isostearate, or a mixture thereof.
  • the surfactant can be classified as an emulsifier.
  • the emulsifier can be in a range of from about 1 wt% to about 5 wt% of the formula, about 2 wt% to about 3.5 wt% of the composition, less than, equal to, or greater than about 1 wt%, 1.5, 2, 2.5, 3, 3.5, 4, 4.5, or about 5 wt% of the composition.
  • Emulsifiers typically employed in the compositions of the present invention include anionic, nonionic and cationic emulsifiers. See, e.g., Encyclopedia of Chemical Technology, KIRK-OTHMER, volume 22, pp. 333-432, 3rd edition, 1979, Wiley, for the definition of the properties and (emulsifying) functions of the emulsifiers, in particular pp.
  • emulsifiers useful in the formula of the invention include as nonionic emulsifiers, fatty acids, fatty alcohols, polyethoxylated fatty alcohols or polyglycerolated fatty alcohols, such as polyethoxylated stearyl alcohols or cetylstearyl alcohols, esters of fatty acid and sucrose, and glucose alkyl esters, in particular polyoxyethylenated Ci-Ce alkyl glucose fatty esters, and as anionic emulsifiers, C16-C30 fatty acids neutralized by amines, ammonia or the alkali metal salts thereof.
  • cationic emulsifiers examples include quaternary amines, amine oxides and amines, e.g., alkyl amines, alkyl imidazolines, ethoxylated amines, quaternary compounds, and quaternized esters. Cationic emulsifiers may also provide a conditioning effect.
  • a particularly useful blend of emulsifiers is a blend of AB IL EM 90 and sorbitan olivate.
  • emulsifiers include sodium stearyl glutamate; a mixture of C12-16 alcohols, palmitic acid, and hydrogenated lecithin; hydrogenated coco-glycerides; a mixture of polyglyceryl-6 stearate and polyglyceryl-6 behenate; glyceryl oleate citrate; a mixture of arachidyl alcohol, behenyl alcohol, and arachidyl glucoside; a mixture of ethylhexyl olivate, sodium acrylates copolymer, and polyglyceryl-4 olivate; a mixture of PEG- 100 and glyceryl stearate; glyceryl stearate; PEG-2 stearate; or a mixture thereof.
  • the oil phase is in a range of from about 2 wt% to about 15 wt% of the cosmetic formula, about 2 wt% to about 10 wt%, less than, equal to, or greater than about 2 wt%, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, or about 15 wt%.
  • the oil phase can include caprylic capric triglyceride, a Cl 5- 19 alkane.
  • caprylic capric triglyceride is in a range of from about 1 wt% to about 5 wt% of the cosmetic formula, about 2 wt% to about 4 wt%, less than, equal to, or greater than about 1 wt%, 1.5, 2, 2.5, 3, 3.5, 4, 4.5, or about 5 wt%.
  • the C15-19 alkane is in a range of from about 1 wt% to about 5 wt% of the cosmetic formula, about 2 wt% to about 4 wt%, less than, equal to, or greater than about 1 wt%, 1.5, 2, 2.5, 3, 3.5, 4, 4.5, or about 5 wt%.
  • the oil phase can additionally, or alternatively, include a mixture of olus, vegetable oil, hydrogenated vegetable oil, candelilla wax; arggania spinosa kernel oil; a mixture of helianthus annuus seed oil, tocopherol, and vegetable oil; cocos necifera oil; crambe abyssinica seed oil; or a mixture thereof.
  • the active component is in a range of from about 15 wt% to about 35 wt% of the cosmetic formula, about 20 wt% to about 30 wt%, less than, equal to, or greater than 15 wt%, 16, 171, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, or about 35 wt%.
  • the active component can include any component or mixture of components to achieve a desired result.
  • active components include lactic acid, a hyaluronic acid, vitamin E, saccharomyces/xylinum/black tea ferment, diglucosyl gallic acid, adenosine, panthenol, dimethylmethoxy chromanol, alpha-glucan oligosaccharide, thermus thermophilus ferment, hydrolyzed hyaluronic acid, caffeine, acetyl di -peptide- 1 cetyl ester, glycerin, niacinamide, swertia chirata extract, creatine, or a mixture thereof.
  • the mixture of gels described and surfactant(s) herein above, allow for the relatively high amount of active component.
  • the ability of the formulation to have a high amount of active component can enhance the formulation’s effectiveness.
  • the formulation can include a chelant or a mixture of two or more chelants.
  • suitable chelants can include tetrasodium glutamate diacetate (GLDA), ethylenediaminetetraacetic acid (EDTA), ethylenediamine-N, N’ -disuccinic acid (EDDS), NT A, EDDS, IDS, methylglycinediacetic acid (MGDA), L-glutamic acid N,N- diacetic acid (GLDA), ethylenediamine-N, N-diglutaric acid (EDDG), ethylenediamine-N, N’- dimalonic acid (EDDM), 3-hydroxy-2,2-iminodisuccinic acid (HIDS), 2- hydroxyethyliminodiacetic acid (HEID A), methylglycine N,N-diacetic acid trisodium salt (MGDA), sodium gluconate, or a mixture thereof.
  • GLDA methylglycinediacetic acid
  • GLDA L
  • the formulas herein can contain a variety of other optional components suitable for rendering such compositions more cosmetically or aesthetically acceptable or to provide them with additional usage benefits.
  • Such conventional optional ingredients are well- known to those skilled in the art. These include any cosmetically acceptable ingredients such as those found in the CTFA International Cosmetic Ingredient Dictionary and Handbook, 7th edition, edited by Wenninger and McEwen, (The Cosmetic, Toiletry, and Fragrance Association, Inc., Washington, D.C., 1997).
  • cosmetically acceptable means a material (e.g., compound or composition) which is suitable for use in contact with skin, hair or other suitable substrate.
  • a pH of the cosmetic formula is in a range of from about 5 to about 7, about 5.5 to about 6.5, less than, equal to, or greater than about 5, 5.5, 6, 6.5, or about 7.
  • the cosmetic formula can be made using any suitable method.
  • the cosmetic formula can be made by combining the gel mixture, surfactant, and oil phase. All the components can be stirred or otherwise mixed to form the final cosmetic formula.
  • the cosmetic formula can be used in a variety of ways.
  • the cosmetic formula can be topically applied to a user’s skin.
  • the cosmetic formula can be topically applied by hand, with an applicator, or both. Examples of applicators can include brushes, pads, sponges, or the like.
  • the cosmetic formula can be applied once daily (e.g., once every 24 hours) or multiple times throughout the day. For example, the cosmetic formula can be applied two times, three times, four times, and so on within a 24 hour period.
  • Various cosmetic formulas according to the instant disclosure will be tested according to sensory testing protocol before (“pick-up”), during, and after application of the cosmetic formulation.
  • the sensory testing protocol can include testing for appearance, texture, and odor at various timings.
  • the cosmetic formulation will be tested in appearance for glossiness, and in texture for firmness, stickiness, and stringiness.
  • Aspect 1 provides a cosmetic formula comprising: a gel mixture in a range of from about 0.1 wt% to about 2 wt% of the cosmetic formula and comprising: sphingomas ferment extract; xanthan gum; and a mixture of hydroxy ethyl acrylate/sodium acryloyldimethyl taurate copolymer & sorbitan isostearate; a surfactant in a range of from about 0.1 wt% to about 2 wt% of the cosmetic formula and comprising sodium stearoyl glutamate; an oil phase in a range of from about 2 wt% to about 15 wt% of the cosmetic formula and comprising: caprylic capric triglyceride; a Cl 5- 19 alkane; and an active component, wherein a pH of the cosmetic formula is in a range of from about 5 to about 7; a viscosity of the cosmetic formula is in a range of from about 1500 cPs to about 5000 cP
  • Aspect 2 provides the cosmetic formula of Aspect 1, wherein the gel mixture is in a range of from about 0.3 wt% to about 1 wt% of the cosmetic formula.
  • Aspect 3 provides the cosmetic formula of any of Aspects 1 or 2, wherein sphingomas ferment extract is in a range of from about 0.05 wt% to about 0.40 wt% of the cosmetic formula; xanthan gum is in a range of from about 0.05 wt% to about 0.30 wt% of the cosmetic formula; and the mixture of hydroxy ethyl acrylate/sodium acryloyldimethyl taurate copolymer & sorbitan isostearate is in a range of from about 0.15 wt% to about 0.50 wt% of the cosmetic formula.
  • Aspect 4 provides the cosmetic formula of any of Aspects 1-3, wherein sphingomas ferment extract is in a range of from about 0.15 wt% to about 0.30 wt% of the cosmetic formula; xanthan gum is in a range of from about 0.10 wt% to about 0.20 wt% of the cosmetic formula; and the mixture of hydroxyethyl acrylate/sodium acryloyldimethyl taurate copolymer & sorbitan isostearate is in a range of from about 0.20 wt% to about 0.40 wt% of the cosmetic formula.
  • Aspect 5 provides the cosmetic formula of any of Aspects 1-4, wherein the surfactant component is in a range of from about 0.1 wt% to about 1.5 wt% of the cosmetic formula.
  • Aspect 6 provides the cosmetic formula of any of Aspects 1-5, wherein the oil phase is in a range of from about 2 wt% to about 10 wt% of the cosmetic formula.
  • Aspect 7 provides the cosmetic formula of any of Aspects 1-6, wherein the caprylic capric triglyceride is in a range of from about 1 wt% to about 5 wt% of the cosmetic formula.
  • Aspect 8 provides the cosmetic formula of any of Aspects 1-7, wherein the Cl 5- 19 alkane is in a range of from about 1 wt% to about 5 wt% of the cosmetic formula.
  • Aspect 9 provides the cosmetic formula of any of Aspects 1-8, wherein the active component is in a range of from about 15 wt% to about 35 wt% of the cosmetic formula.
  • Aspect 10 provides the cosmetic formula of any of Aspects 1-9, wherein the active component is in a range of from about 20 wt% to about 30 wt% of the cosmetic formula.
  • Aspect 11 provides the cosmetic formula of any of Aspects 1-10, wherein the active component comprises lactic acid, a hydrolyzed hyaluronic acid, vitamin E, saccharomyces/xylinum/black tea ferment, diglucosyl gallic acid, or a mixture thereof.
  • Aspect 12 provides the cosmetic formula of any of Aspects 1-11, wherein the cosmetic formula is a serum.
  • Aspect 13 provides the cosmetic formula of any of Aspects 1-12, wherein the cosmetic formula can be used for skin fine lines reduction, improving skin firmness, evening skin tone, strengthening skin barrier, hydrating skin, enhancing skin natural radiance, or a combination thereof.
  • Aspect 14 provides a method of making the cosmetic formula of any of Aspects 1-13, the method comprising combining the gel mixture, surfactant, and oil phase.
  • Aspect 15 provides a method of using the cosmetic formula of any of Aspects 1-14, the method comprising applying the cosmetic formula to a user’s skin.
  • Aspect 16 provides the method of Aspect 15, wherein the cosmetic formula is applied twice within 24 hours.

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  • Cosmetics (AREA)

Abstract

Divers aspects de l'invention concernent une formule de produit cosmétique. La formule de produit cosmétique comprend un mélange de gel dans une plage allant d'environ 0,1 % en poids à environ 2 % en poids de la formule de produit cosmétique. Le mélange de gel comprend de l'extrait de ferment de Sphingomonas, de la gomme xanthane et un mélange de copolymère d'acrylate d'hydroxyéthyle/d'acryloyldiméthyl taurate de sodium et d'isostéarate de sorbitanne. La formule de produit cosmétique comprend également un agent tensioactif représentant environ 0,1 % en poids à environ 2 % en poids de la formule de produit cosmétique et comprenant du glutamate de stéaroyle de sodium. La formule de produit cosmétique comprend également une phase huileuse dans une plage allant d'environ 2 % en poids à environ 15 % en poids de la formule de produit cosmétique. La phase huileuse comprend le triglycéride caprylique et caprique, et un alcane en C15-19. La formule comprend en outre un composant actif. Le pH de la formule de produit cosmétique est compris entre environ 5 et environ 7. La viscosité de la formule de produit cosmétique est comprise entre environ 1500 cPs et environ 5000 cPs. La formule de produit cosmétique est suffisamment stable pendant au moins 2 mois à une température d'environ 45 °C.
PCT/US2024/018170 2023-03-03 2024-03-01 Formules de produit cosmétique utilisées pour administration d'une grande diversité de composants actifs Pending WO2024186663A1 (fr)

Priority Applications (1)

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CN202480025043.7A CN121099981A (zh) 2023-03-03 2024-03-01 用于递送多种活性组分的化妆品制剂

Applications Claiming Priority (2)

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FR2301986A FR3146280A1 (fr) 2023-03-03 2023-03-03 Formulations cosmétiques et leurs utilisations
FRFR2301986 2023-03-03

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WO2024186663A1 true WO2024186663A1 (fr) 2024-09-12

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CN (1) CN121099981A (fr)
FR (1) FR3146280A1 (fr)
NL (1) NL2035476B1 (fr)
WO (1) WO2024186663A1 (fr)

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FR3146280A1 (fr) 2024-09-06
CN121099981A (zh) 2025-12-09

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