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WO2024073740A3 - Improved loop–mediated isothermal amplification methods, compositions, kits, and systems for detecting nucleic acids - Google Patents

Improved loop–mediated isothermal amplification methods, compositions, kits, and systems for detecting nucleic acids Download PDF

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Publication number
WO2024073740A3
WO2024073740A3 PCT/US2023/075630 US2023075630W WO2024073740A3 WO 2024073740 A3 WO2024073740 A3 WO 2024073740A3 US 2023075630 W US2023075630 W US 2023075630W WO 2024073740 A3 WO2024073740 A3 WO 2024073740A3
Authority
WO
WIPO (PCT)
Prior art keywords
kits
compositions
systems
nucleic acids
amplification methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2023/075630
Other languages
French (fr)
Other versions
WO2024073740A2 (en
Inventor
Thomas E. Schaus
Jiyoun JEONG
Nikhil GOPALKRISHNAN
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3eo Health Inc
Original Assignee
3eo Health Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 3eo Health Inc filed Critical 3eo Health Inc
Publication of WO2024073740A2 publication Critical patent/WO2024073740A2/en
Publication of WO2024073740A3 publication Critical patent/WO2024073740A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The present disclosure provides methods, kits, compositions, devices, and systems for detecting a target nucleic acid, such as a viral RNA. In one aspect, described herein are methods of detecting the target nucleic acid. In other aspects, described herein are compositions, kits, devices, and systems suitable to practice the methods described herein to detect the target nucleic acid.
PCT/US2023/075630 2022-09-30 2023-09-29 Improved loop–mediated isothermal amplification methods, compositions, kits, and systems for detecting nucleic acids Ceased WO2024073740A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263412327P 2022-09-30 2022-09-30
US63/412,327 2022-09-30

Publications (2)

Publication Number Publication Date
WO2024073740A2 WO2024073740A2 (en) 2024-04-04
WO2024073740A3 true WO2024073740A3 (en) 2024-05-10

Family

ID=90479191

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2023/075630 Ceased WO2024073740A2 (en) 2022-09-30 2023-09-29 Improved loop–mediated isothermal amplification methods, compositions, kits, and systems for detecting nucleic acids

Country Status (1)

Country Link
WO (1) WO2024073740A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190382856A1 (en) * 2014-04-28 2019-12-19 Quest Diagnostics Investments Llc Molecular detection of enterovirus and parechovirus
US20210340622A1 (en) * 2020-03-23 2021-11-04 Talis Biomedical Corporation Polynucleotides for amplification and detection of sars-cov-2

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20190382856A1 (en) * 2014-04-28 2019-12-19 Quest Diagnostics Investments Llc Molecular detection of enterovirus and parechovirus
US20210340622A1 (en) * 2020-03-23 2021-11-04 Talis Biomedical Corporation Polynucleotides for amplification and detection of sars-cov-2

Also Published As

Publication number Publication date
WO2024073740A2 (en) 2024-04-04

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