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WO2024073481A3 - Microdevices for use in cell seeding onto two- and three-dimensional biocompatible constructs - Google Patents

Microdevices for use in cell seeding onto two- and three-dimensional biocompatible constructs Download PDF

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Publication number
WO2024073481A3
WO2024073481A3 PCT/US2023/075223 US2023075223W WO2024073481A3 WO 2024073481 A3 WO2024073481 A3 WO 2024073481A3 US 2023075223 W US2023075223 W US 2023075223W WO 2024073481 A3 WO2024073481 A3 WO 2024073481A3
Authority
WO
WIPO (PCT)
Prior art keywords
microdevices
cell seeding
dimensional biocompatible
seeding onto
biocompatible constructs
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2023/075223
Other languages
French (fr)
Other versions
WO2024073481A2 (en
Inventor
Jeremy M. PERRELLE
Amir MCCORMICK
Jasmine M. GAMBOA
Andrew J. BORELAND
N. Sanjeeva MURTHY
Zhiping Pang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rutgers State University of New Jersey
Original Assignee
Rutgers State University of New Jersey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rutgers State University of New Jersey filed Critical Rutgers State University of New Jersey
Priority to EP23873870.2A priority Critical patent/EP4594648A2/en
Publication of WO2024073481A2 publication Critical patent/WO2024073481A2/en
Publication of WO2024073481A3 publication Critical patent/WO2024073481A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/02Form or structure of the vessel
    • C12M23/06Tubular
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/38Caps; Covers; Plugs; Pouring means
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00Constructional details, e.g. recesses, hinges
    • C12M23/46Means for fastening

Landscapes

  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Clinical Laboratory Science (AREA)
  • Materials For Medical Uses (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

This disclosure provides microdevices and methods of using the microdevices to grow and seed cells onto various biocompatible materials such that those cells can later be successfully engrafted into an animal (e.g., human).
PCT/US2023/075223 2022-09-28 2023-09-27 Microdevices for use in cell seeding onto two- and three-dimensional biocompatible constructs Ceased WO2024073481A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP23873870.2A EP4594648A2 (en) 2022-09-28 2023-09-27 Microdevices for use in cell seeding onto two- and three-dimensional biocompatible constructs

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US202263377467P 2022-09-28 2022-09-28
US63/377,467 2022-09-28

Publications (2)

Publication Number Publication Date
WO2024073481A2 WO2024073481A2 (en) 2024-04-04
WO2024073481A3 true WO2024073481A3 (en) 2024-05-10

Family

ID=90479345

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2023/075223 Ceased WO2024073481A2 (en) 2022-09-28 2023-09-27 Microdevices for use in cell seeding onto two- and three-dimensional biocompatible constructs

Country Status (2)

Country Link
EP (1) EP4594648A2 (en)
WO (1) WO2024073481A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070166819A1 (en) * 2006-01-16 2007-07-19 Reliance Life Sciences Pvt. Ltd. Device for culturing and transporting cells
US20120174345A1 (en) * 2009-09-16 2012-07-12 Illinois Tool Works Inc. Multi-piece snap clip fastener
US20180141047A1 (en) * 2015-05-21 2018-05-24 Intecrypt B.V. Microfluidic device for in vitro 3d cell culture experimentation
US20190330584A1 (en) * 2018-03-19 2019-10-31 Massachusetts Institute Of Technology Organ-on-chip platforms with reduced fluid volume

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5216115A (en) 1990-06-12 1993-06-01 Rutgers, The State University Of New Jersey Polyarylate containing derivatives of the natural amino acid L-tyrosine
US5099060A (en) 1990-06-12 1992-03-24 Rutgers, The State University Of New Jersey Synthesis of amino acid-derived bioerodible polymers
US6120491A (en) 1997-11-07 2000-09-19 The State University Rutgers Biodegradable, anionic polymers derived from the amino acid L-tyrosine
US6048521A (en) 1997-11-07 2000-04-11 Rutgers, The State University Copolymers of tyrosine-based polyarlates and poly(alkylene oxides)
CA2579619C (en) 1997-11-07 2012-01-03 Rutgers, The State University Radio-opaque polymeric biomaterials
US20060034769A1 (en) 2004-08-13 2006-02-16 Rutgers, The State University Radiopaque polymeric stents
US11472918B2 (en) 2012-02-03 2022-10-18 Rutgers, The State University Of New Jersey Polymeric biomaterials derived from phenolic monomers and their medical uses
WO2021055090A1 (en) 2019-09-17 2021-03-25 Rutgers, The State University Of New Jersey Degradable phase changing polymers for dental/medical applications

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070166819A1 (en) * 2006-01-16 2007-07-19 Reliance Life Sciences Pvt. Ltd. Device for culturing and transporting cells
US20120174345A1 (en) * 2009-09-16 2012-07-12 Illinois Tool Works Inc. Multi-piece snap clip fastener
US20180141047A1 (en) * 2015-05-21 2018-05-24 Intecrypt B.V. Microfluidic device for in vitro 3d cell culture experimentation
US20190330584A1 (en) * 2018-03-19 2019-10-31 Massachusetts Institute Of Technology Organ-on-chip platforms with reduced fluid volume

Also Published As

Publication number Publication date
WO2024073481A2 (en) 2024-04-04
EP4594648A2 (en) 2025-08-06

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