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WO2023203596A1 - Procédé de production d'endoprothèse et endoprothèse - Google Patents

Procédé de production d'endoprothèse et endoprothèse Download PDF

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Publication number
WO2023203596A1
WO2023203596A1 PCT/JP2022/018008 JP2022018008W WO2023203596A1 WO 2023203596 A1 WO2023203596 A1 WO 2023203596A1 JP 2022018008 W JP2022018008 W JP 2022018008W WO 2023203596 A1 WO2023203596 A1 WO 2023203596A1
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WO
WIPO (PCT)
Prior art keywords
wire
point
stent
junction
manufacturing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2022/018008
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English (en)
Japanese (ja)
Inventor
完太 佐々木
講 瀧田
由佳 香田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Olympus Corp
Original Assignee
Olympus Corp
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Filing date
Publication date
Application filed by Olympus Corp filed Critical Olympus Corp
Priority to PCT/JP2022/018008 priority Critical patent/WO2023203596A1/fr
Publication of WO2023203596A1 publication Critical patent/WO2023203596A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure

Definitions

  • the present invention relates to a method for manufacturing a stent and a stent.
  • Patent Document 1 discloses a method for manufacturing a stent in which a wire is knitted in a zigzag pattern from one end of a jig to the other end, and then the wire is knitted in a zigzag pattern from the other end of the jig to one end.
  • the stent of Patent Document 1 includes a hooking portion in which two portions of the wire are hooked to each other. In forming the hook, after passing the end of the wire radially inside one section, it is necessary to pull the entire length of the remaining section of the wire that is not yet braided. Since the stent manufacturing method of Patent Document 1 uses one long wire, it takes time to form each engaging portion, and as a result, it takes a long time to manufacture the stent.
  • the present invention has been made in view of the above-mentioned circumstances, and an object of the present invention is to provide a stent manufacturing method and stent that can shorten the stent manufacturing time.
  • One aspect of the present invention is a method for manufacturing a stent formed by weaving a wire from a first point through a continuous path to the first point, the method comprising: providing a first wire and a second wire; , braiding the first wire from the first point to a joining point, braiding the second wire from the joining point to the first point, one end of the first wire and the second wire at the first point. and joining the other end of the first wire and the other end of the second wire to each other at the joining point, the first wire and the second wire
  • Another aspect of the invention is a method of manufacturing a stent formed by weaving a wire through a continuous path from a first point to a second point, the method comprising: providing a first wire and a second wire; , braiding the first wire from the first point to a junction between the first and second points, braiding the second wire from the junction to the second point, and joining one end of the first wire and one end of the second wire to each other at a joining point, wherein the first wire and the second wire divide the total length of the wires constituting the stent into two.
  • This is a method of manufacturing a stent having divided lengths.
  • Another aspect of the invention is to weave a wire through a continuous first path from a first point to a second point, and from a third point near the first point to a fourth point near the second point.
  • the third wire and the fourth wire have a length that is half of the total length of the wire constituting the stent.
  • Another aspect of the invention is a stent formed from a wire braided from a first point through a continuous path to said first point, the first wire being braided from said first point to a junction point.
  • Another aspect of the invention is a stent formed from a wire woven through a continuous path from a first point to a second point, the stent being formed from a wire woven through a continuous path from the first point to the first point and the second point. a first wire braided to a junction between said junction point and a second wire braided from said junction point to said second point;
  • the stent is provided with a joint portion in which one end of the stent and a joint portion are joined to each other.
  • Another aspect of the invention includes a wire woven through a continuous first path from a first point to a second point; and another wire woven through a continuous second path up to four points, the first wire woven from the first point to the second point, and the third point.
  • the stent includes a joint portion where one end of the third wire and one end of the fourth wire are joined to each other.
  • FIG. 2 is a side view of the stent according to the first embodiment.
  • FIG. 2 is a developed view of the stent of FIG. 1;
  • FIG. 2 is a partially enlarged view of the stent of FIG. 1;
  • It is a figure which shows the procedure of forming an engaging part.
  • It is a flowchart of the manufacturing method of the stent concerning a 1st embodiment. It is a figure showing an example of the jig used in a manufacturing method.
  • FIG. 2 is a developed view of a modified example of the stent in FIG. 1;
  • FIG. 2 is a developed view of another modification of the stent in FIG. 1;
  • FIG. 3 is a developed view of a stent according to a second embodiment.
  • FIG. 7 is a side view of a stent according to a third embodiment.
  • FIG. 12 is a partially enlarged view of the stent of FIG. 11; It is a flowchart of the manufacturing method of the stent concerning a 3rd embodiment.
  • FIGS. 1 and 2 A stent and a method for manufacturing the stent according to a first embodiment of the present invention will be described with reference to the drawings.
  • the stent 10 according to this embodiment is formed by weaving wire into a cylindrical shape.
  • FIG. 2 is a developed view of the stent 10 expanded in the circumferential direction, with the vertical direction corresponding to the longitudinal direction of the stent 10 and the lateral direction corresponding to the circumferential direction of the stent 10.
  • the stent 10 has a starting point (first point) S/E, and is formed by sequentially weaving two wires 1 and 2 from the starting point S/E through a continuous predetermined path to the starting point S/E. has been done. That is, the starting point S/E is also the end point of the predetermined route.
  • the stent 10 includes a first wire 1 woven in a zigzag pattern along a predetermined path from a starting point S/E to a junction point A, and a first wire 1 woven from a starting point S/E to a starting point S/E.
  • first wire 1 is shown as a thick solid line
  • second wire 2 is shown as a thick broken line.
  • the starting point S/E is an arbitrary position on the predetermined route.
  • the junction point A is a position different from the starting point S/E on the predetermined route, and is determined depending on the starting point S/E and the length of the first wire 1.
  • the starting point S/E is located between one end 10a and the other end 10b of the stent 10, and the joining point A is located between the starting point S/E and the other end 10b. Therefore, the first wire 1 is braided from the starting point S/E to the junction point A via the other end 10b, and the second wire 2 is braided from the junction point A to the starting point S/E via the one end 10a. ing.
  • the central portion of the stent 10 in the longitudinal direction is placed at the stenosis of the tubular organ and contributes to relief of the stenosis. Since the strength of the joints 5A, 5B is weaker than the other parts of the stent 10, it is preferable that at least one of the joints 5A, 5B be disposed at a position away from the center of the stent 10. Therefore, as shown in FIGS. 1 and 2, the starting point S/E is preferably a position away from the center of the stent 10 toward one end 10a.
  • the stent 10 is formed from two wires 1, 2 connected in series with each other. Therefore, the wires 1 and 2 have a length obtained by dividing the total length L of the wires constituting the stent 10 (that is, the total length of the predetermined route) into two, and are each shorter than the total length L. In this embodiment, each of the wires 1 and 2 has a length L/2, which is half the total length L.
  • the two portions of the wires 1 and 2 are mutually caught at the intersection of the plurality of rows of vertical lines a1, a2, ..., a11 and the plurality of rows of circumferential lines b1, b2, ..., b11. It has a hooking part 7 (see FIG. 3).
  • the plurality of vertical lines a1, a2, . . . extend in the longitudinal direction of the stent 10 and divide the circumference of the stent 10 into a plurality of equal parts.
  • the stent 10 extend in the circumferential direction of the stent 10, equally divide the length of the stent 10 into a plurality of lines, and are orthogonal to the vertical lines.
  • the stent 10 also has a straight line intersection part 8 (see FIG. 3) where the two substantially straight straight parts 8a and 8b of the wires 1 and 2 intersect with each other.
  • the two parts of the wires 1, 2 are mutually displaced at the engagement part 7 and the straight intersection part 8.
  • the starting point S/E and the joining point A where the joining parts 5A and 5B are formed may be at positions other than the engaging part 7 and the straight intersection part 8.
  • FIG. 3 shows an enlarged view of a portion of stent 10.
  • Each of the zigzag wires 1 and 2 has peaks 7a and valleys 7b arranged alternately in the circumferential direction of the stent 10.
  • the mountain portion 7a is a portion of the wires 1 and 2 that is bent toward one end 10a and protrudes toward the other end 10b.
  • the trough portion 7b is a portion of the wires 1 and 2 that is bent toward the other end 10b and protrudes toward the one end 10a.
  • the engaging portion 7 is formed from a peak portion 7a and a valley portion 7b that are engaged with each other.
  • the peak portions 7a and the valley portions 7b are connected to each other so as to be freely displaceable.
  • the stent 10 can maintain its tubular shape using only the wires 1 and 2, and can be flexibly curved with little or no elastic force to return to the straight shape.
  • FIG. 4 explains the procedure for forming the engaging part 7.
  • this procedure includes a step of passing the tip of the wire 1 or 2 through the radially inner side of the peak portion 7a or the trough portion 7b (left figure), and a step of pulling the wire 1 or 2 (center figure). , and the step of folding back the wire 1 or 2 (see the right figure).
  • the pulling process it is necessary to pull the entire length of the remaining part of the wire 1 or 2 that is not yet braided. Therefore, the longer the wires 1, 2, the longer the time required for the pulling process.
  • the method for manufacturing the stent 10 includes step SA1 of preparing a jig 40, step SA2 of preparing two wires 1 and 2, and setting the first wire 1 as a starting point.
  • Step SA3 of knitting from S/E to joining point A Step SA4 of knitting the second wire 2 from joining point A to starting point S/E, Step SA5 of removing the knitted wires 1 and 2 from the jig 40, and the starting point Step SA6 of joining one end of the first wire 1 and one end of the second wire 2 to each other in S/E, and joining the other end of the first wire 1 and the other end of the second wire 2 to each other at the joining point A.
  • step SA7 of joining The method for manufacturing the stent 10 includes step SA8 of attaching an X-ray visibility marker to the braided wires 1 and 2, step SA9 of pre-cleaning the braided wires 1 and 2, and heat treatment of the braided wires 1 and 2.
  • the process may further include step SA10.
  • FIG. 6 shows an example of the jig 40.
  • the jig 40 includes a cylindrical shaft 41 and a plurality of pins 42 attached to the outer peripheral surface of the shaft 41.
  • a hole for inserting a pin 42 is provided on the outer circumferential surface of the shaft 41 at a position corresponding to the intersection in the exploded view of FIG.
  • pins 42 are inserted and attached to holes corresponding to peaks 7a and troughs 7b.
  • step SA2 a first wire 1 and a second wire 2 each having a length L/2, which is half the total length L necessary for forming the stent 10, are prepared. Wires 1, 2 may be prepared by splitting one wire of length L in half, or may be prepared separately.
  • the order of step SA1 and step SA2 is arbitrary, and step SA1 may be performed after step SA2.
  • step SA3 the first wire 1 is knitted along a predetermined path from the starting point S/E to the joining point A via the other end 10b while being wound in the circumferential direction.
  • step SA4 the second wire 2 is knitted along a predetermined path from the joining point A to the starting point S/E via the one end 10a while being wound in the circumferential direction.
  • steps SA3 and SA4 include the step of forming the engaging portion 7 shown in FIG. 4. Specifically, in step SA3, in the process of weaving the first wire 1 from the one end 10a to the joining point A, the engaging portion 7 is formed. In step SA4, the engaging portion 7 is formed in the process of knitting from the joining point A to the starting point S/E and in the process of knitting from the other end 10b to the starting point S/E.
  • steps SA3 and SA4 steps SA8, SA9, and SA10 are performed as necessary.
  • the X-ray visible marker is used to enable the stent 10 inserted into the body to be observed from outside the body using X-rays.
  • Step SA8 may be omitted.
  • step SA10 when the wires 1 and 2 are made of a shape memory alloy such as NiTi, the wires 1 and 2 are subjected to heat treatment to cause the wires 1 and 2 to memorize the knitted shape. Before step SA10, pre-cleaning of the wires 1 and 2 in step SA9 may be performed.
  • step SA5 the pin 42 is removed from the shaft 41, and then the braided wires 1 and 2 are removed from the shaft 41.
  • step SA6 one end of the first wire 1 and one end of the second wire 2 are joined to each other at the starting point S/E to form the first joint portion 5A.
  • step SA7 the other end of the first wire 1 and the other end of the second wire 2 are joined to each other at the joining point A to form the second joining part 5B.
  • Steps SA6 and SA7 may be executed not only after steps SA8 to SA10 and SA5 but also at any timing after step SA4. Further, step SA6 may be executed during step SA4.
  • the ends of the wires 1 and 2 are joined in steps SA6 and SA7 by caulking, laser welding, close winding, or using an X-ray visible marker.
  • Caulking is a method of crimping the ends of the wires 1 and 2 and the pipe by caulking a metal pipe into which the ends of the wires 1 and 2 are inserted.
  • Tight winding is a method in which one end of the wires 1, 2 is tightly wound around the other end of the wires 1, 2.
  • the ends of the wires 1, 2 may each be fixed to an X-ray visible marker.
  • the stent 10 is formed from two wires 1 and 2 having a length L/2, which is obtained by dividing the entire length L. Therefore, in forming the engaging part 7 in steps SA3 and SA4, the lengths of the wires 1 and 2 to be pulled are shorter than when one wire of length L is used, and the wires 1 and 2 are pulled.
  • the time required for the process is shortened.
  • the pulling process occupies a large proportion of the time required to form the engaging parts 7, the time taken to form each engaging part 7 can be effectively shortened by shortening the time required for the pulling process. Thereby, the manufacturing time of the stent 10 can be effectively shortened.
  • the stent 10 includes many hooking portions 7, and the time required to form the hooking portions 7 occupies much of the time required for steps SA3 and SA4 for braiding the wires 1 and 2. Therefore, by shortening the time required to form each engaging portion 7, the entire manufacturing time can be effectively shortened.
  • the number of joining parts 5B increases by one by using the two wires 1 and 2, the time required for joining is sufficiently shorter than the time required for forming a large number of engaging parts 7. Therefore, by using two wires 1 and 2, the overall manufacturing time of the stent 10 can be shortened.
  • the stent 10 is formed from two wires 1 and 2 having equal lengths, but the number and length of the wires forming the stent 10 are not limited to this. , can be changed as appropriate.
  • the stent 10 may be formed from three or more wires. That is, at least one of the first wire 1 and the second wire 2 may include two or more wires that are joined to each other.
  • FIG. 7 shows a developed view of a stent 10 formed from three wires 1, 2, 3.
  • Wire 1 solid line
  • wire 2 two-dot chain line
  • the wire 3 (broken line) is knitted from the second joining point A2 to the starting point S/E via one end 10a.
  • the ends of the wires 1 and 3 are joined to each other at the joint 5A of the starting point S/E
  • the ends of the wires 1 and 2 are joined to each other at the joint 5B of the first joint A1
  • the ends of the wires 1 and 2 are joined to each other at the joint 5B of the first joint A1.
  • each of wires 1, 2, 3 is shorter than half the total length L/2. Therefore, according to the first modification, the manufacturing time of the stent 10 can be further shortened compared to the stent 10 of FIGS. 1 and 2.
  • the lengths of the plurality of wires forming the stent 10 may be different from each other.
  • FIG. 8 shows a developed view of a stent 10 formed from a first wire 1 (solid line) with a length of L/3 and a second wire 2 (broken line) with a length of 2L/3.
  • the starting point S/E can be selected arbitrarily, and the joining point A is determined by the length of the first wire 1. Therefore, by using wires of different lengths, the positions of the joints 5A, 5B can be adjusted. For example, as shown in FIG. 8, both junctions 5A and 5B can be located off-center of the stent 10.
  • Example 1 of the present invention one wire with a length of 3/L and one wire with a length of 2L/3 were used.
  • Example 2 of the present invention three wires with a length of 3/L were used.
  • the comparative example one wire of length L was used.
  • the wire is a NiTi wire.
  • the reduction rate is the reduction rate of the time required to knit all the wires, based on the comparative example.
  • Example 2 As can be seen from Table 1, compared to the comparative example, the time required to knit the wire was reduced by about 27% in Example 1 and by about 33% in Example 2. In this manner, it was confirmed that by using a plurality of wires having lengths obtained by dividing the total length L, the time for manufacturing the stent 10 can be effectively shortened. Further, in Example 2 using three wires, the manufacturing time could be further shortened than in Example 1 using two wires.
  • FIG. 9 shows a developed view of the stent 20 according to this embodiment.
  • the stent 20 of this embodiment differs from the stent 10 of the first embodiment in the way the wires are woven.
  • the stent 20 has a starting point (first point) S and an ending point (second point) E that is different from the starting point S.
  • the starting point S is located at or near one end 20a of the stent 20, and the ending point E is arranged at or near the other end 20b of the stent 20.
  • the stent 20 is formed by sequentially weaving two wires 1 and 2 from a starting point S through a continuous predetermined path to an ending point E.
  • the stent 20 includes a first wire 1 that is woven in a zigzag spiral along a predetermined route from a starting point S to a junction point A, and a first wire 1 that is woven in a zigzag spiral along a predetermined route from a junction point A to an end point E.
  • the second wire 2 is spirally knitted, a joint 5 formed at a joint A, and joints 6A and 6B formed at a starting point S and an ending point E, respectively.
  • the first wire 1 is shown as a thick solid line
  • the second wire 2 is shown as a thick broken line.
  • the junction point A is an arbitrary position between the starting point S and the ending point E on the predetermined route, and is determined according to the length of the first wire 1.
  • a joint portion 5 at a joint point A one end of the first wire 1 and one end of the second wire 2 are joined to each other.
  • a joint 6A is formed where the other end of the first wire 1 is joined to another part of the first wire 1, and at the end point E, the other end of the second wire 2 is joined to another part of the second wire 2.
  • a joint portion 6B joined to other parts is formed.
  • the stent 20 is formed from two wires 1, 2 connected in series with each other. Therefore, the wires 1 and 2 have a length obtained by dividing the total length L of the wires constituting the stent 20 (that is, the total length of the predetermined route) into two, and are each shorter than the total length L. In this embodiment, each of the wires 1 and 2 has a length L/2, which is half the total length L.
  • the circumferential lines b1, b2, ..., b8 extend continuously in a spiral shape around the central axis of the stent 20.
  • Each of the zigzag wires 1 and 2 has peaks 7a and valleys 7b arranged alternately in the circumferential direction of the stent 20.
  • the stent 20 has engaging portions 7 at intersections where the circumferential lines b1, b2,..., b8 intersect with a plurality of vertical lines.
  • vertical lines have been omitted to simplify the drawing.
  • the method for manufacturing the stent 20 includes step SB1 of preparing a jig 40, step SB2 of preparing two wires 1 and 2, and setting the first wire 1 as a starting point.
  • Step SB3 of knitting the second wire 2 from S to the junction point A Step SB4 of knitting the second wire 2 from the junction point A to the end point E, Step SB5 of removing the knitted wires 1 and 2 from the jig 40, and
  • the method includes step SB6 of joining one end of the first wire 1 and one end of the second wire 2 to each other, and step SB7 of joining the ends of the wires 1 and 2 at the starting point S and the ending point E, respectively.
  • the method for manufacturing stent 20 may further include steps SA8, SA9, and SA10 described in the first embodiment.
  • step SB1 pins 42 are inserted and attached to holes in shaft 41 corresponding to peaks 7a and troughs 7b.
  • step SB2 similarly to step SA2, the first wire 1 and the second wire 2 each having a length L/2, which is half the total length L necessary for forming the stent 20, are prepared.
  • the order of step SB1 and step SB2 is arbitrary.
  • step SB3 the first wire 1 is weaved along a predetermined path from the starting point S to the joining point A while being spirally wound in the circumferential direction.
  • step SB4 the second wire 2 is knitted along a predetermined path from the joining point A to the end point E while being spirally wound in the circumferential direction.
  • steps SB3 and SB4 each include a step of forming the engaging portion 7.
  • step SB5 the braided wires 1 and 2 are removed from the shaft 41, similarly to step SA5.
  • step SB6 similarly to step SA6, one end of the first wire 1 and one end of the second wire 2 are joined to each other at the joining point A to form the joining part 5.
  • step SB7 the other ends of the wires 1 and 2 are joined to other parts of the wires 1 and 2, respectively, to form joints 6A and 6B.
  • the stent 20 is formed from two wires 1 and 2 having a length L/2, which is obtained by dividing the entire length L. Therefore, similarly to the first embodiment, the time for forming the individual engaging portions 7 can be effectively shortened, and thereby the time for manufacturing the stent 20 can be effectively shortened.
  • the first modification and the second modification of the first embodiment can be applied.
  • the stent 20 may be formed from three or more wires. That is, at least one of the first wire 1 and the second wire 2 may include two or more wires that are joined to each other.
  • the lengths of the plurality of wires forming the stent 20 may be different from each other. For example, if the length of the first wire 1 is L/3, the length of the second wire 2 is 2L/3, and the junction point A is located away from the center of the stent 20 toward one end 20a. It's okay.
  • FIG. 11 and 12 show a side view and a partially enlarged view, respectively, of the stent 30 according to this embodiment.
  • the stent 30 differs from the stent 10 of the first embodiment in the way the wires are woven.
  • the stent 30 has a first starting point (first point) S1, a first ending point (second point) E1 different from the first starting point S1, and a second starting point (third point) located near the first starting point S1. S2, and a second end point (fourth point) E2 located near the first end point E1 and different from the second start point S2.
  • the starting points S1 and S2 are arranged at or near one end 30a of the stent 30, and the ending points E1 and E2 are arranged at or near the other end 30b of the stent 30.
  • the stent 30 weaves the wire 1 from a first starting point S1 through a continuous predetermined first path to a first end point E1, and then from a second starting point S2 through a continuous predetermined path different from the first path. It is formed by sequentially weaving the two wires 3 and 4 through the second path to the second end point E2.
  • the stent 30 includes a first wire 1 woven in a zigzag pattern from a first starting point S1 to a first end point E1 along a predetermined first path, and a predetermined first wire 1 woven from a second starting point S2 to a junction point A.
  • a third wire 3 is woven in a zigzag pattern along two routes
  • a fourth wire 4 is woven in a zigzag pattern along a predetermined second route from the junction point A to the second end point E2
  • a third wire 3 is woven in a zigzag pattern along two routes. and joint parts 6A, 6B, 6C, and 6D formed at starting points S1, S2 and ending points E1, E2.
  • the second wire 2 knitted from the second starting point S2 to the second ending point E2 consists of the third wire 3 and the fourth wire 4.
  • the first wire 1 is shown as a solid line
  • the second wire 2 is shown as a broken line.
  • the junction point A is an arbitrary position between the second starting point S2 and the second ending point E2 on the predetermined second route, and is determined according to the length of the third wire 3.
  • one end of the third wire 3 and one end of the fourth wire 4 are joined to each other.
  • One end of the first wire 1 is joined to the third wire 3 at the joining part 6A at the first starting point S1, and the other end of the third wire 3 is joined to the first wire 1 at the joining part 6B at the second starting point S2.
  • the other end of the first wire 1 is joined to the fourth wire 4 at the joint 6C at the first end point E1, and the other end of the fourth wire 4 is joined to the first wire 1 at the joint 6D at the second end point E2. has been done.
  • the stent 30 is thus formed from two wires 1, 2 woven through different paths, the second wire 2 consisting of two wires 3, 4 connected in series with each other. Ru. Therefore, the wires 3 and 4 have a length that is half of the total length L of the wires constituting the stent 30 (that is, the total length of the second path), and are each shorter than the length L/2.
  • each of the zigzag wires 1 and 2 has peaks 7a and valleys 7b arranged alternately in the circumferential direction of the stent 30.
  • the crest 7a of the first wire 1 and the trough 7b of the second wire 2 form the engaging part 7, and the trough 7b of the first wire 1 and the crest 7a of the second wire 2 form the engaging part 7. are doing.
  • the method for manufacturing the stent 30 includes a step SC1 of preparing a jig 40, a step SC2 of preparing a first wire 1 and a second wire 2, and a step SC2 of preparing a first wire 1 and a second wire 2.
  • step SC1 of preparing a jig 40
  • step SC2 of preparing a first wire 1 and a second wire 2
  • step SC2 of preparing a first wire 1 and a second wire 2.
  • the method for manufacturing stent 30 may further include steps SA8, SA9, and SA10 described in the first embodiment.
  • step SC1 pins 42 are inserted and attached to holes in shaft 41 corresponding to peaks 7a and troughs 7b.
  • step SC2 similarly to step SA2, the first wire 1 and the second wire 2 each having a length L/2, which is half the total length L necessary for forming the stent 30, are prepared.
  • the second wire 2 a third wire 3 and a fourth wire 4 are prepared.
  • the third wire 3 and the fourth wire 4 may have mutually equal lengths or may have mutually different lengths.
  • the order of step SC1 and step SC2 is arbitrary.
  • step SC3 the first wire 1 is weaved along a predetermined first path from the first starting point S1 to the first ending point E1 while spirally winding the first wire 1 in a zigzag manner in the circumferential direction.
  • step SC41 the third wire 3 is knitted along a predetermined second path from the second starting point S2 to the joining point A while spirally winding the third wire 3 in a zigzag manner in the circumferential direction.
  • step SC42 the fourth wire 4 is weaved along a predetermined second path from the joining point A to the second end point E2 while spirally winding the fourth wire 4 in a zigzag manner in the circumferential direction.
  • steps SC41 and SC42 include a step of forming the engaging portion 7.
  • step SC5 the braided wires 1, 3, and 4 are removed from the shaft 41, similarly to step SA5.
  • step SC6 similarly to step SA6, one end of the third wire 3 and one end of the fourth wire 4 are joined to each other at the joining point A to form the joining part 5.
  • step SB7 both ends of the wire 1 are joined to the wires 3 and 4, respectively, to form joints 6A and 6C.
  • the other ends of the wires 3 and 4 are joined to the wire 1, respectively, to form joint parts 6B and 6D.
  • the second wire 2 of the stent 30 is composed of two wires 3 and 4, and each wire 3 and 4 has a length obtained by dividing the entire length L/2 of the second wire 2. It has a certain quality. Therefore, in forming the engaging portion 7 in steps SC41 and SC42, the lengths of the wires 3 and 4 to be pulled are shortened compared to the case where one second wire with a length L/2 is used, and the wire 3 , 4 is shortened. Thereby, it is possible to effectively shorten the time for forming each of the engaging portions 7, and to effectively shorten the time for manufacturing the stent 30.
  • the first modification and the second modification of the first embodiment can be applied.
  • the second wire 2 of the stent 30 may be composed of three or more wires. That is, at least one of the third wire 3 and the fourth wire 4 may include two or more wires that are joined to each other.
  • the lengths of the plurality of wires constituting the second wire 2 may be different from each other.
  • the length of the third wire 3 is L/3
  • the length of the fourth wire 4 is 2L/3
  • the junction point A is located away from the center of the stent 30 toward one end 30a. It's okay.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

L'invention concerne un procédé de production d'endoprothèse est destiné à former une endoprothèse (10) par tissage d'un fil le long d'un trajet continu à partir d'un premier point (S/E) et jusqu'au premier point (S/E). Le procédé de production d'endoprothèse comprend : la préparation d'un premier fil (1) et d'un deuxième fil (2) ; le tissage du premier fil (1) à partir d'un premier point (S/E) jusqu'à un point de jonction (A) ; le tissage du deuxième fil (2) à partir du point de jonction (A) jusqu'au premier point (S/E) ; l'assemblage d'une extrémité de chacun des premier et deuxième fils (1, 2) l'une à l'autre au niveau du premier point (S/E) ; et l'assemblage de l'autre extrémité de chacun des premier et deuxième fils (1, 2) l'une à l'autre au niveau du point de jonction (A). Les premier et deuxième fils (1, 2) ont chacun une longueur qui est égale à la moitié de la longueur totale du fil constituant l'endoprothèse (10).
PCT/JP2022/018008 2022-04-18 2022-04-18 Procédé de production d'endoprothèse et endoprothèse Ceased WO2023203596A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/JP2022/018008 WO2023203596A1 (fr) 2022-04-18 2022-04-18 Procédé de production d'endoprothèse et endoprothèse

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/JP2022/018008 WO2023203596A1 (fr) 2022-04-18 2022-04-18 Procédé de production d'endoprothèse et endoprothèse

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WO2023203596A1 true WO2023203596A1 (fr) 2023-10-26

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100016930A (ko) * 2008-08-05 2010-02-16 주식회사 엠아이텍 스텐트
JP2018505720A (ja) * 2015-01-12 2018-03-01 マイクロベンション インコーポレイテッド ステント
JP2020508795A (ja) * 2017-03-06 2020-03-26 カーディバスキュラー・ラブ・ソチエタ・ペル・アツィオーニ・オ・ブレヴェメンテ・シーブイ・ラブ・ソチエタ・ペル・アツィオーニＣＡＲＤＩＯＶＡＳＣＵＬＡＲ ＬＡＢ Ｓ．Ｐ．Ａ． ｏ ｂｒｅｖｅｍｅｎｔｅ ＣＶ ＬＡＢ Ｓ．Ｐ．Ａ． 多層の管腔内プロテーゼアセンブリおよび製造方法

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20100016930A (ko) * 2008-08-05 2010-02-16 주식회사 엠아이텍 스텐트
JP2018505720A (ja) * 2015-01-12 2018-03-01 マイクロベンション インコーポレイテッド ステント
JP2020508795A (ja) * 2017-03-06 2020-03-26 カーディバスキュラー・ラブ・ソチエタ・ペル・アツィオーニ・オ・ブレヴェメンテ・シーブイ・ラブ・ソチエタ・ペル・アツィオーニＣＡＲＤＩＯＶＡＳＣＵＬＡＲ ＬＡＢ Ｓ．Ｐ．Ａ． ｏ ｂｒｅｖｅｍｅｎｔｅ ＣＶ ＬＡＢ Ｓ．Ｐ．Ａ． 多層の管腔内プロテーゼアセンブリおよび製造方法

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