WO2023068343A1 - Food or beverage, food additive, supplement, cosmetic, antibody, pharmaceutical and production methods thereof - Google Patents

Abstract

[Problem] To provide a food or beverage, a food additive, a supplement, a cosmetic, an antibody and a pharmaceutical, which enable rapid countermeasures against pandemics with the use of an antibody, and production methods thereof. [Solution] An antibody 1, a food or beverage 10, a food additive 20, a supplement 30, a pharmaceutical 40 and a cosmetic 50 that comprise IgY antibody and/or IgG antibody prepared outside the human body and also comprise a naturally occurring starting material 2 having microbicidal effect. The naturally occurring starting material 2 preferably contains a plant extract. The plant extract preferably contains a grapefruit extract or a tea extract.

Description

Food and drink, food additives, supplements, cosmetics, antibodies, pharmaceuticals, and manufacturing methods thereof

TECHNICAL FIELD The present invention relates to food and drink, food additives, supplements, cosmetics, antibodies, pharmaceuticals, and methods for producing the same.

The new coronavirus is raging and has become a pandemic all over the world, but from the past, pandemics caused by viruses such as influenza, SARS, and MERS sometimes strike. As a countermeasure against such a pandemic, for example, a technique disclosed in Patent Literature 1 has been developed.

JP 2020-172497 A

There is an urgent need to develop various technologies using antibodies in response to the pandemics described above.

The present invention has been made in view of such circumstances, and food and drink, food additives, supplements, cosmetics, antibodies, medicines, and their The object is to provide a manufacturing method.

In order to achieve the above object, the food or drink according to the present invention is characterized by containing an antibody.

INDUSTRIAL APPLICABILITY According to the present invention, it is possible to provide a food or drink containing an antibody. In other words, food and drink can quickly respond to pandemics caused by viruses using antibodies without the need for clinical trials (trials) that are required for vaccines, pharmaceuticals, and the like.

It is preferable that the food and drink of the present invention further contain a natural raw material having a bactericidal effect.
The natural raw material preferably contains a plant extract.
The plant extract preferably contains a grapefruit extract or a tea extract.
The grapefruit extract preferably contains a grapefruit seed extract.
The tea extract preferably contains tea catechins.

The food and drink of the present invention are preferably sterilized by heating in a low temperature atmosphere of 50°C to 65°C.
The sterilization time is preferably within 60 minutes.
The food and drink of the present invention are preferably pressurized and sterilized in a high pressure atmosphere of 500 to 1500 atm.
The food and drink of the present invention are preferably sterilized using radiation.

The food or drink of the present invention is preferably spray, jelly, candy, capsule, tablet, round, powder, granule, fine grain, troche, liquid or gel.
The spray form is preferably in the form of an intraoral spray.
The capsule is preferably in the form of an enteric capsule.
At least one of dairy products, fermented foods, and drinks is preferred.

The antibody is preferably an antibody produced outside the human body.
Said antibody preferably comprises an IgY antibody and/or an IgG antibody.

In order to achieve the above object, the food additive according to the present invention is characterized by containing an antibody.
According to the present invention, an antibody-containing food additive can be provided. In other words, food additives can quickly respond to pandemics caused by viruses using antibodies without the need for clinical trials (trials) that are required for vaccines, pharmaceuticals, and the like.

It is preferable that the food additive of the present invention further contains a natural raw material having a bactericidal effect.
The natural raw material preferably contains a plant extract.
The plant extract preferably contains a grapefruit extract or a tea extract.
The grapefruit extract preferably contains a grapefruit seed extract.

The tea extract preferably contains tea catechins.
The food additive is preferably sterilized by heating in a low temperature atmosphere of 50°C to 65°C.
The sterilization time is preferably within 60 minutes.

The food additive of the present invention is preferably pressurized and sterilized in a high pressure atmosphere of 500 to 1500 atm.
The food additive of the present invention is preferably sterilized using radiation.

The food additive of the present invention is preferably in the form of spray, jelly, candy, capsule, tablet, round, powder, granule, fine grain, troche, liquid or gel.

The spray form is preferably in the form of an intraoral spray.
The capsule is preferably in the form of an enteric capsule.
The antibody is preferably an antibody produced outside the human body.
Said antibody preferably comprises an IgY antibody and/or an IgG antibody.
The food additive of the present invention is preferably at least one of dairy products, fermented foods, and drinks.

In order to achieve the above object, a supplement according to the present invention is characterized by containing an antibody.
According to the present invention, a supplement containing an antibody can be provided. In other words, supplements can quickly respond to pandemics caused by viruses using antibodies without the need for clinical trials (trials) that are required for vaccines, pharmaceuticals, and the like.

The supplement of the present invention preferably further contains natural raw materials having a bactericidal effect.
The natural raw material preferably contains a plant extract.
The plant extract preferably contains a grapefruit extract or a tea extract.
The grapefruit extract preferably contains a grapefruit seed extract.
The tea extract preferably contains tea catechins.

The supplement of the present invention is preferably sterilized by heating in a low temperature atmosphere of 50°C to 65°C.
The sterilization time is preferably within 60 minutes.
The supplement of the present invention is preferably pressurized and sterilized under a high pressure atmosphere of 500 to 1500 atm.
The supplement of the present invention is preferably sterilized using radiation.
The supplement of the present invention is preferably in the form of spray, jelly, candy, capsule, tablet, round, powder, granule, fine grain, troche, liquid or gel.

The spray form is preferably in the form of an intraoral spray.
The capsule is preferably in the form of an enteric capsule.
The antibody is preferably an antibody produced outside the human body.
Said antibody preferably comprises an IgY antibody and/or an IgG antibody.
The supplement is preferably at least one of dairy products, fermented foods, and drinks.

In order to achieve the above object, the cosmetic according to the present invention is characterized by containing an antibody.
According to the present invention, cosmetics containing antibodies can be provided. In other words, cosmetics can quickly respond to pandemics caused by viruses using antibodies without the need for clinical trials (trials) that are required for vaccines, pharmaceuticals, and the like.
It is preferable that the cosmetic of the present invention further contains a natural raw material having a bactericidal effect.
The natural raw material preferably contains a plant extract.
The plant extract preferably contains a grapefruit extract or a tea extract.
The grapefruit extract preferably contains a grapefruit seed extract.
The tea extract preferably contains tea catechins.

The cosmetic of the present invention is preferably sterilized by heating in a low temperature atmosphere of 50°C to 65°C.
The sterilization time is preferably within 60 minutes.
The cosmetics of the present invention are preferably pressurized and sterilized in a high-pressure atmosphere of 500 to 1500 atm.
The cosmetics of the present invention are preferably sterilized using radiation.
The cosmetic of the present invention preferably further contains a negatively charged substance.

The cosmetic product of the present invention is preferably in at least one of spray, cream, liquid, gel, paste, emulsion, and mousse.
The spray form preferably includes a skin spray.
The cream preferably includes at least one of skin cream, lip cream, nasal cavity cream, and eye cream.
The antibody is preferably an antibody produced outside the human body.
Said antibody preferably comprises an IgY antibody and/or an IgG antibody.

In order to achieve the above object, the antibody according to the present invention is characterized by being produced outside the human body, and preferably contains an IgY antibody and/or an IgG antibody.
In order to achieve the above object, the pharmaceutical according to the present invention is characterized by containing an antibody.

It is preferable that the medicament of the present invention further contains a natural raw material having a bactericidal effect.
The natural raw material preferably contains a plant extract.
The plant extract preferably contains a grapefruit extract or a tea extract.
The grapefruit extract preferably contains a grapefruit seed extract.
The tea extract preferably contains tea catechins.

The medicament of the present invention is preferably sterilized by heating in a low temperature atmosphere of 50°C to 65°C.
The sterilization time is preferably within 60 minutes.
The pharmaceutical of the present invention is preferably pressurized and sterilized in a high-pressure atmosphere of 500 to 1500 atm.
The medicament of the present invention is preferably sterilized using radiation.
The medicament of the present invention is preferably in the form of spray, jelly, candy, capsule, tablet, round, powder, granule, fine grain, troche, liquid, or gel.
The spray form is preferably in the form of an intraoral spray.
The capsule is preferably in the form of an enteric capsule.

The pharmaceutical of the present invention is preferably at least one of dairy products, fermented foods, and drinks.
The antibody is preferably produced outside the human body.
Said antibody preferably comprises an IgY antibody and/or an IgG antibody.
The medicament of the present invention is preferably used to prevent and/or treat infectious diseases in subjects.
The infectious disease preferably includes one or more infectious diseases selected from the group consisting of coronavirus, influenza, SARS, and MARS.
The subject is preferably a mammal, and the mammal is preferably a human.

In order to achieve the above object, the production method according to the present invention provides antibodies, antibody-blended foods and drinks, food additives, supplements, cosmetics, and at least one of pharmaceuticals in a low-temperature atmosphere of 50°C to 65°C. It is characterized by being manufactured by heating and sterilizing.
In the production method of the present invention, the sterilization time is preferably within 60 minutes.
In the production method of the present invention, it is preferable that the sterilization treatment is carried out under a high pressure atmosphere of 500 to 1500 atm.
As for the production method, it is preferable to sterilize at least one of antibodies, antibody-containing foods and drinks, food additives, supplements, cosmetics, and pharmaceuticals using radiation.
In order to achieve the above object, the food or drink according to the present invention is characterized by blending a natural raw material having a bactericidal effect.
The natural raw material preferably contains a plant extract.
The plant extract preferably contains a grapefruit extract or a tea extract.
The grapefruit extract preferably contains a grapefruit seed extract.
The tea extract preferably contains tea catechins.
In order to achieve the above object, the food additive according to the present invention preferably contains a natural raw material having a bactericidal effect.
The natural raw material preferably contains a plant extract.
The plant extract preferably contains a grapefruit extract or a tea extract.
The grapefruit extract preferably contains a grapefruit seed extract.
The tea extract preferably contains tea catechins.
In order to achieve the above object, the supplement according to the present invention is characterized by blending natural raw materials having a bactericidal effect.
The natural raw material preferably contains a plant extract.
The plant extract preferably contains a grapefruit extract or a tea extract.
The grapefruit extract preferably contains a grapefruit seed extract.
The tea extract preferably contains tea catechins.
In order to achieve the above object, the cosmetic according to the present invention is characterized by blending a natural raw material having a bactericidal effect.
The natural raw material preferably contains a plant extract.
The plant extract preferably contains a grapefruit extract or a tea extract.
The grapefruit extract preferably contains a grapefruit seed extract.
The tea extract preferably contains tea catechins.
In order to achieve the above object, the medicament according to the present invention is characterized by containing a natural raw material having a bactericidal effect.
The natural raw material preferably contains a plant extract.
The plant extract preferably contains a grapefruit extract or a tea extract.
The grapefruit extract preferably contains a grapefruit seed extract.
The tea extract preferably contains tea catechins.

INDUSTRIAL APPLICABILITY According to the present invention, antibodies can be used to promptly respond to viral pandemics.

BRIEF DESCRIPTION OF THE DRAWINGS It is a figure which shows the antibody, food/beverage products, food additive, supplement, medicine, and cosmetics which concern on embodiment of this invention. FIG. 4 is a diagram showing another food/drink, food additive, supplement, medicine, and cosmetic according to an embodiment of the present invention; FIG. 4 is a diagram showing yet another food/drink, food additive, supplement, medicine, and cosmetic according to an embodiment of the present invention;

Embodiments of the antibodies, food and drink, food additives, supplements, medicines, cosmetics, and methods for producing the same of the present invention are described in detail below. FIG. 1 is a diagram showing an antibody 1, a food or drink 10, a food additive 20, a supplement 30, a medicine 40, and a cosmetic 50 according to an embodiment of the present invention.

[Antibody 1]
The antibody 1 is preferably an antibody 1 produced outside the human body, and the antibody 1 is more specifically an IgY antibody, which is an immunoglobulin derived from chicken eggs, and/or an IgG antibody. More specifically, an antibody derived from a mouse. It preferably includes an IgG antibody that is a globulin. IgY and IgG antibodies preferably include monoclonal or polyclonal antibodies. An IgY antibody can be produced by culturing and purifying an extract extracted from chicken eggs, and an IgG antibody can be produced by culturing and purifying an extract extracted from a mouse. Antibody 1 produced outside the human body (external to the human body such as a hen's egg or a mouse) does not need to immunize the human body with an antigen, so it is said that there is no risk of allergic reaction. IgY antibodies and IgG antibodies are capable of neutralizing antigens, more specifically neutralizing viral bodies, viral proteins, viral genes, and ACE2 receptor proteins (spike proteins).

Here, the antibody (for example, immunoglobulin) 1 is a glycoprotein molecule produced by B cells among lymphocytes, and has the function of recognizing and binding to a molecule (antigen) such as a specific protein. Antibody 1 is mainly present in blood and body fluids, and recognizes and binds to, for example, bacteria, viruses, and cells infected with microorganisms that have invaded the body as antigens. When Antibody 1 binds to an antigen, phagocytic cells such as leukocytes and microphages recognize and phagocytize the complex of the antigen and Antibody 1 and work to remove it from the body, and immune cells such as lymphocytes bind and become immune. It is something that provokes a reaction.

[Embodiments of Food and Beverage 10, Food Additive 20, Supplement 30, and Medicine 40]
The food and drink 10, the food additive 20, the supplement 30, and the medicine 40 according to the embodiment of the present invention are characterized by containing the antibody 1 described above.
The food and drink 10, the food additive 20, the supplement 30, and the medicine 40 of the present invention preferably further contain one or more natural raw materials 2 that have bactericidal and antioxidant effects and do not cause protein denaturation of the antibody 1. The food and drink 10, the food additive 20, the supplement 30, and the medicine 40 are subjected to heat treatment for the purpose of sterilization, for example, and by controlling the pH to 4 or less, the protein is denatured and the effect of the antibody 1 is reduced. However, by blending one or more natural raw materials 2 that have a bactericidal effect and an antioxidant effect and do not cause protein denaturation of the antibody 1, the antibody can be obtained without heat treatment and without controlling the pH to 4 or less. 1 can suppress protein denaturation.

The natural raw material 2 preferably contains a plant extract, and the plant extract preferably contains a grapefruit extract or a tea extract. Furthermore, the grapefruit extract preferably contains a grapefruit seed extract, and the tea extract preferably contains tea catechins. Grapefruit seed extracts extracted from grapefruit seeds and tea catechins extracted from tea leaves have excellent bactericidal effects. Grapefruit seed extract, that is, liquid active ingredients extracted from grayfruit seeds, more specifically, extracts containing oil (essential oils) extracted from grapefruit seeds (GSE) and tea catechins have antioxidant and antiseptic effects. A remarkable effect can be obtained by blending the food and drink 10, the food additive 20, the supplement 30, and the medicine 40 containing the antibody (protein) 1 which has an action and is easily oxidized.

In addition, the food and drink 10, the food additive 20, the supplement 30, and the medicine 40 of the present invention are preferably heated and sterilized in a low-temperature atmosphere of 50°C to 65°C (the food and drink 10, the food additive 20, The supplement 30 and the medicine 40 are preferably manufactured by a manufacturing method in which they are heated and sterilized in a low temperature atmosphere of 50° C. to 65° C.). The sterilization time is preferably within 60 minutes. That is, when antibody 1 is treated in a high-temperature atmosphere for a long time, protein denaturation may occur, but sterilization is performed in a low-temperature atmosphere of 50 to 65 ° C., and the sterilization time is within 60 minutes. This can suppress the occurrence of protein denaturation.

Furthermore, the food and drink 10, the food additive 20, the supplement 30, and the medicine 40 of the present invention are preferably pressurized and sterilized in a high pressure atmosphere of 500 to 1500 atm (the food and drink 10, the food additive 20 , the supplement 30 and the medicine 40 are preferably manufactured by a manufacturing method in which they are pressurized and sterilized in a high-pressure atmosphere of 500 to 1500 atm). That is, by performing the sterilization treatment in a high-pressure atmosphere of 500 to 1500 atm, the treatment can be performed in a room temperature atmosphere, and protein denaturation can be suppressed.

Furthermore, the food and drink 10, the food additive 20, the supplement 30, and the medicine 40 of the present invention are preferably sterilized using radiation (manufacturing of the food and drink 10, the food additive 20, the supplement 30, and the medicine 40 is preferably carried out by a manufacturing method in which radiation is used to sterilize and manufacture). That is, by performing a sterilization treatment using radiation, it is possible to realize the treatment in a room temperature atmosphere and suppress the occurrence of protein denaturation.

Blending of one or more natural raw materials 2 described above as a method of suppressing protein denaturation in the food and drink 10, food additive 20, supplement 30, and medicine 40 of the present invention, and sterilization in a low temperature atmosphere of 50 to 65 °C. , sterilization treatment under a high pressure atmosphere of 500 to 1500 atm, and sterilization treatment using radiation may be performed alone, may be appropriately combined with two or more, or may be appropriately combined with three or more. Well, you can do all four.

Here, the food and drink 10, the food additive 20, the supplement 30, and the medicine 40 of the present invention are spray-like, jelly-like, candy-like, capsule-like, tablet-like, round-like, powder-like, granule-like, fine-grain-like, troche. It is preferably in the form of liquid, liquid or gel. That is, by providing the food and drink 10, the food additive 20, the supplement 30, and the medicine 40 in such a form, they can be used for various purposes.

For example, the spray form can be in the form of an oral spray, and the capsule form can be in the form of an enteric capsule.

Also, the food and drink 10, the food additive 20, the supplement 30, and the medicine 40 can be at least one of dairy products, fermented foods, and drinks. Dairy products can be, for example, lactic acid beverages, yogurt, etc. Fermented foods can be natto, kimchi, etc., and drinks can be juices, health drinks, sports drinks, and the like. By forming the food/beverage product 10, the food additive 20, the supplement 30, and the medicine 40 in such a form, it is possible to facilitate ingestion of the food/beverage product 10, the food additive 20, the supplement 30, and the medicine 40 containing the antibody 1. .

Additionally, medicament 40 can be used to prevent and/or treat infections in a subject. Infectious diseases can include one or more infectious diseases selected from the group consisting of coronavirus, influenza, SARS, and MARS. The subject can be a mammal, and the mammal can be a human.

By ingesting the food and drink 10, the food additive 20, the supplement 30, and the medicine 40, the antibody 1 can be used to promptly respond to a virus pandemic.

In addition, by ingesting the above-mentioned food and drink 10, food additives 20, and supplements 30, there is no need for clinical trials (trials) seen with vaccines, pharmaceuticals, etc., and antibody 1 can be used to quickly respond to pandemics caused by viruses. It can be carried out.

The type of food and drink 10 described above is not particularly limited, and food and drink 10 includes beverages and foods. The food and drink 10 include beverages, noodles, confectionery, meat or livestock processed foods, grain processed foods, vegetable processed foods, fruit processed foods, dairy products, oil and fat processed foods, seasonings and the like.

In addition, the food additive 20 is a substance added for the purpose of processing or preserving the food and drink 10, and has technical purposes such as reducing oxidation, coloring the product, enhancing its taste, and the like. added to food for Food additives 20 include coloring agents (including whitening agents), preservatives, antioxidants, acidulants/acidity correctors, and texture imparting agents (stabilizers, emulsifiers, thickeners, gelling agents), and the like. include. The food additive 20 may contain other ingredients for the food additive 20 as desired. Other ingredients include colorants, preservatives, sweeteners, thickeners, stabilizers, gelling agents, antioxidants, emulsifiers, flavors and the like.

Further, the supplement 30 refers to a composition classified as a food for the purpose of supplementing nutrition and maintaining health, and includes health food, functional food, nutritional supplement, and food for specified health uses. The supplement 30 includes, for example, concentrated vitamins, minerals, and other ingredients in tablet, capsule, or powder form. The form of the supplement 30 is not particularly limited as long as it can be administered orally, and the supplement 30 may contain other ingredients that can be used as ingredients for supplements. Other ingredients include polysaccharides, antioxidants, proteins, salts, and the like.

Furthermore, the form of the medicine 40 is not particularly limited, and the medicine 40 is used for prevention and/or treatment of target diseases or lesions. The medicine 40 may contain additives or pharmaceutically acceptable carriers as needed. Such additives or pharmaceutically acceptable carriers include excipients, disintegrants, binders, lubricants, surfactants, buffers, solubilizers, stabilizers, tonicity agents, suspending agents, Turbiding agents, emulsifiers, solvents, thickeners, mucolytic agents, wetting agents, preservatives and the like.

[Embodiment of cosmetics 50]
A cosmetic product 50 according to an embodiment of the present invention is characterized by containing the antibody 1 described above. The type of the cosmetics 50 is not particularly limited, and the cosmetics 50 include lotion, milky lotion, foundation, lipstick, lip balm, cleansing cream, massage cream, mask, hand cream, hand powder, body shampoo, body lotion, body cream, Forms such as bath cosmetics can be included.

The cosmetic product 50 of the present invention preferably further contains one or more natural raw materials 2 that have a bactericidal effect and an antioxidant effect and do not cause protein denaturation of the antibody 1 . For example, the cosmetic 50 is heat-treated for the purpose of sterilization, and by controlling the pH to 4 or less, the protein may be denatured and the effect of the antibody 1 may be reduced. By blending one or more natural raw materials 2 that do not cause protein denaturation of 1, it is possible to suppress protein denaturation of antibody 1 without performing heat treatment and without controlling pH to 4 or less. .

The natural raw material 2 preferably contains a plant extract, and the plant extract preferably contains a grapefruit extract or a tea extract. Furthermore, the grapefruit extract preferably contains a grapefruit seed extract, and the tea extract preferably contains tea catechins. Grapefruit seed extracts extracted from grapefruit seeds and tea catechins extracted from tea leaves have excellent bactericidal effects. Grapefruit seed extract, that is, liquid active ingredients extracted from grayfruit seeds, more specifically, extracts containing oil (essential oils) extracted from grapefruit seeds (GSE) and tea catechins have antioxidant and antiseptic effects. A remarkable effect can be obtained by blending it in the cosmetics 50 containing the antibody (protein) 1 which has an action and is easily oxidized.

In addition, the cosmetic 50 of the present invention is preferably heated and sterilized in a low temperature atmosphere of 50 to 65 ° C. It is preferable to use a manufacturing method that manufactures by The sterilization time is preferably within 60 minutes. That is, when antibody 1 is treated in a high-temperature atmosphere for a long time, protein denaturation may occur, but sterilization is performed in a low-temperature atmosphere of 50 to 65 ° C., and the sterilization time is within 60 minutes. This can suppress the occurrence of protein denaturation.

Furthermore, the cosmetic 50 of the present invention is preferably pressurized and sterilized in a high-pressure atmosphere of 500 to 1500 atm (the cosmetic 50 is produced by pressurizing and sterilizing in a high-pressure atmosphere of 500 to 1500 atm). It is preferably carried out by a manufacturing method that processes and manufactures). That is, by performing the sterilization treatment in a high-pressure atmosphere of 500 to 1500 atm, the treatment can be performed in a room temperature atmosphere, and protein denaturation can be suppressed.

Furthermore, the cosmetics 50 of the present invention are preferably sterilized using radiation (the cosmetics 50 are preferably manufactured by a manufacturing method that sterilizes using radiation). That is, by performing a sterilization treatment using radiation, it is possible to realize the treatment in a room temperature atmosphere and suppress the occurrence of protein denaturation.

As a method for suppressing protein denaturation in the cosmetic product 50 of the present invention, blending of one or more natural raw materials 2 described above, sterilization under a low temperature atmosphere of 50 to 65 ° C., and high pressure atmosphere of 500 to 1500 atmosphere. The sterilization treatment and the sterilization treatment using radiation may each be performed alone, two or more may be appropriately combined, three or more may be appropriately combined, or all four may be performed.

Furthermore, it is preferable that the cosmetic 50 of the present invention further contains a negatively charged substance such as ceramics. That is, antigens (viruses) are often negatively charged, and by adding a negatively charged substance to the cosmetics 50, the negatively charged virus is repelled and the virus is prevented from adhering to the skin. can do. Various substances other than ceramics can be used as the negatively charged substance.

Here, the cosmetic product 50 of the present invention is preferably in at least one of spray, cream, liquid, gel, paste, emulsion, and mousse. That is, by providing the cosmetic product 50 in such a form, it can be used for various purposes.

The spray type preferably includes a skin spray, and the cream type includes at least one of skin cream, lip cream, nasal cavity cream, and eye area (eyelid, outer corner of the eye, lacrimal bag, etc.) cream. preferably included.

With the cosmetics 50 described above, it is possible to quickly respond to pandemics caused by viruses using the antibody 1 without the need for clinical trials (trials) that are required for vaccines, pharmaceuticals, and the like.

It goes without saying that the present invention is not limited to the above-described embodiments, and various modifications and applications are possible.

For example, in the above-described embodiment, the food and drink 10, the food additive 20, the supplement 30, the cosmetic 40, and the medicine 50 contain both the antibody 1 and the natural raw material 2, and are shown in FIG. As shown in FIG. 3, it may contain only the antibody 1 without containing the natural raw material 2, or may contain only the natural raw material 2 without containing the antibody 1 as shown in FIG.

However, it is preferable to include both the antibody 1 and the natural raw material 2 because protein denaturation of the food and drink 10, the food additive 20, the supplement 30, the cosmetic 40, and the medicine 50 can be suppressed. form.

In addition, although the natural raw material 2 contains a plant extract, other natural raw materials 2 can be used to achieve the desired effect.

However, the natural raw material 2 preferably contains a grapefruit extract or a tea extract, more specifically, than a plant extract.

1: Antibody 2: Natural raw materials 10: Food and drink 20: Food additives 30: Supplements 40: Medicines 50: Cosmetics

Claims (115)

A food or drink characterized by containing an antibody. 2. The food or drink according to claim 1, further comprising a natural raw material having a bactericidal effect. 3. The food or drink according to claim 2, wherein the natural raw material contains a plant extract. 4. The food or drink according to claim 3, wherein the plant extract contains a grapefruit extract or a tea extract. 5. The food or drink according to claim 4, wherein the grapefruit extract contains a grapefruit seed extract. 5. The food or drink according to claim 4, wherein the tea extract contains tea catechins. The food or drink according to claim 1, which is sterilized by heating in a low temperature atmosphere of 50°C to 65°C. 8. The food or drink according to claim 7, wherein the sterilization time is within 60 minutes. 2. The food or drink according to claim 1, which is pressurized and sterilized in a high-pressure atmosphere of 500 to 1500 atm. The food or drink according to claim 1, wherein the food or drink is sterilized using radiation. It is in the form of spray, jelly, candy, capsule, tablet, round, powder, granule, fine grain, troche, liquid or gel. Food and drink according to any one of the items. 12. The food and drink according to claim 11, wherein the spray is in the form of an intraoral spray. 12. The food and drink according to claim 11, wherein the capsule is in the form of an enteric capsule. 14. The food or drink according to any one of claims 1 to 13, characterized by being at least one of dairy products, fermented foods, and drinks. 15. The food or drink according to any one of claims 1 to 14, wherein the antibody is an antibody produced outside the human body. 16. Food and drink according to claim 15, wherein the antibody comprises an IgY antibody and/or an IgG antibody. A food additive characterized by containing an antibody. 18. The food additive according to claim 17, further comprising a natural raw material having a bactericidal effect. 19. The food additive according to claim 18, wherein said natural raw material contains a plant extract. 20. The food additive according to claim 19, wherein the plant extract comprises grapefruit extract or tea extract. 21. The food additive according to claim 20, wherein said grapefruit extract comprises grapefruit seed extract. 21. The food additive according to claim 20, wherein said tea extract contains tea catechins. The food additive according to claim 17, which is sterilized by heating in a low temperature atmosphere of 50°C to 65°C. 24. The food additive according to claim 23, wherein the sterilization time is within 60 minutes. 18. The food additive according to claim 17, which is pressurized and sterilized under a high pressure atmosphere of 500 to 1500 atm. 19. Food additive according to claim 18, characterized in that it is sterilized using radiation. It is in the form of spray, jelly, candy, capsule, tablet, round, powder, granule, fine grain, troche, liquid or gel. The food additive according to any one of claims 1 to 3. 28. The food additive according to claim 27, wherein said spray is in the form of an intraoral spray. 28. The food additive according to claim 27, wherein said capsule is in the form of an enteric capsule. 30. The food additive according to any one of claims 17 to 29, which is used as at least one of dairy products, fermented foods, and drinks. 31. The food additive according to any one of claims 17 to 30, wherein said antibody is an antibody produced outside the human body. 32. Food additive according to claim 31, characterized in that said antibody comprises an IgY antibody and/or an IgG antibody. A supplement characterized by containing an antibody. 34. The supplement according to claim 33, further comprising a natural raw material having a bactericidal effect. 35. The supplement of Claim 34, wherein the natural source material comprises a plant extract. 36. The supplement of claim 35, wherein the plant extract comprises grapefruit extract or tea extract. 37. The supplement of claim 36, wherein said grapefruit extract comprises grapefruit seed extract. 38. The supplement according to claim 37, wherein the tea extract comprises tea catechins. 34. The supplement according to claim 33, which is sterilized by heating in a low temperature atmosphere of 50°C to 65°C. 40. The supplement according to claim 39, wherein the sterilization time is within 60 minutes. 34. The supplement according to claim 33, which is pressurized and sterilized under a high pressure atmosphere of 500 to 1500 atmospheres. 34. The supplement of claim 33, wherein the supplement is sterilized using radiation. According to any of claims 33 to 42, it is spray-like, jelly-like, candy-like, capsule-like, tablet-like, round-like, powder-like, granule-like, fine-grain-like, lozenge-like, liquid-like, or gel-like. A supplement according to any one of paragraphs. 44. A supplement according to claim 43, wherein said spray is in the form of an oral spray. 44. The supplement of claim 43, wherein said capsule is in the form of an enteric capsule. 46. The supplement according to any one of claims 33 to 45, characterized by being at least one of dairy products, fermented foods, and drinks. 47. The supplement according to any one of claims 33 to 46, wherein the antibody is an antibody produced outside the human body. 48. Supplement according to claim 47, characterized in that said antibodies comprise IgY antibodies and/or IgG antibodies. A cosmetic characterized by containing an antibody. 50. Cosmetics according to claim 49, characterized by further comprising a natural raw material having a bactericidal effect. 51. Cosmetics according to claim 50, wherein the natural ingredients comprise plant extracts. 52. Cosmetics according to claim 51, wherein the plant extract comprises grapefruit extract or tea extract. 53. Cosmetics according to claim 52, wherein the grapefruit extract comprises a grapefruit seed extract. 53. Cosmetics according to claim 52, wherein the tea extract contains tea catechins. 50. The cosmetic product according to claim 49, which is sterilized by heating in a low temperature atmosphere of 50 to 65[deg.]C. 56. Cosmetics according to claim 55, characterized in that the sterilization time is within 60 minutes. 50. Cosmetics according to claim 49, characterized by being pressurized and sterilized under a high pressure atmosphere of 500 to 1500 atmospheres. 50. Cosmetics according to claim 49, characterized in that they are sterilized using radiation. 59. Cosmetics according to any one of claims 49 to 58, further comprising a negatively charged substance. 60. The cosmetic product according to any one of claims 49 to 59, which is in at least one of spray, cream, liquid, gel, paste, emulsion, and mousse. 61. A cosmetic product according to Claim 60, wherein said spray comprises a skin spray. 61. A cosmetic product according to claim 60, wherein said cream comprises at least one of skin cream, lip cream, nasal cream and eye cream. 63. The cosmetic product according to any one of claims 49 to 62, wherein the antibody is an antibody produced outside the human body. 64. Cosmetics according to claim 63, characterized in that said antibodies comprise IgY antibodies and/or IgG antibodies. An antibody characterized by being produced outside the human body. 66. Antibody according to claim 65, characterized in that it comprises an IgY antibody and/or an IgG antibody. A medicine characterized by containing an antibody. 68. The pharmaceutical according to claim 67, further comprising a natural raw material having a bactericidal effect. 69. The medicament according to claim 68, wherein said natural source material comprises a plant extract. 70. The medicament according to claim 69, wherein the plant extract comprises grapefruit extract or tea extract. 71. The medicament according to claim 70, wherein said grapefruit extract comprises grapefruit seed extract. 71. The pharmaceutical according to claim 70, wherein the tea extract contains tea catechins. The pharmaceutical according to claim 67, which is sterilized by heating in a low temperature atmosphere of 50°C to 65°C. 74. The pharmaceutical according to claim 73, wherein the sterilization time is within 60 minutes. 68. The medicament according to claim 67, which is pressurized and sterilized under a high pressure atmosphere of 500 to 1500 atm. 68. A medicament according to claim 67, characterized in that it is sterilized using radiation. According to claims 67 to 76, it is in the form of spray, jelly, candy, capsule, tablet, round, powder, granule, fine granule, lozenge, liquid or gel. A medicament according to any one of the clauses. 78. The medicament according to claim 77, wherein said spray is in the form of an intraoral spray. 78. The medicament according to claim 77, wherein said capsule is in the form of an enteric capsule. 80. The pharmaceutical according to any one of claims 67 to 79, characterized by being at least one of dairy products, fermented foods, and drinks. 68. The medicament according to claim 67, wherein said antibody is produced outside the human body. 68. A medicament according to claim 67, characterized in that said antibody comprises an IgY antibody and/or an IgG antibody. 68. The medicament according to claim 67, which is used for preventing and/or treating an infectious disease in a subject. 84. The medicament according to claim 83, wherein the infectious disease comprises one or more infectious diseases selected from the group consisting of coronavirus, influenza, SARS, and MARS. 84. The medicament of claim 83, wherein said subject is a mammal. 86. A medicament according to claim 85, wherein said mammal is a human. A manufacturing method characterized by heating and sterilizing at least one of an antibody, an antibody-blended food and drink, a food additive, a supplement, a cosmetic, and a drug in a low-temperature atmosphere of 50°C to 65°C. 88. The manufacturing method according to claim 87, wherein the sterilization time is within 60 minutes. 88. The production method according to claim 87, wherein the production is performed by pressurization and sterilization under a high pressure atmosphere of 500 to 1500 atmospheres. 88. The production method according to claim 87, wherein at least one of antibodies, antibody-blended foods and drinks, food additives, supplements, cosmetics, and pharmaceuticals is produced by sterilizing with radiation. A food or drink characterized by containing a natural raw material having a bactericidal effect. 92. The food or drink according to claim 91, wherein the natural raw material contains a plant extract. 93. The food or drink according to claim 92, wherein the plant extract comprises a grapefruit extract or a tea extract. 94. The food or drink product according to claim 93, wherein the grapefruit extract comprises a grapefruit seed extract. 94. The food or drink according to claim 93, wherein the tea extract contains tea catechins. A food additive characterized by containing a natural raw material having a bactericidal effect. 97. The food additive according to claim 96, wherein said natural raw material comprises a plant extract. 98. The food additive according to claim 97, wherein the plant extract comprises grapefruit extract or tea extract. 99. The food additive of claim 98, wherein said grapefruit extract comprises grapefruit seed extract. 99. The food additive according to claim 98, wherein said tea extract contains tea catechins. A supplement characterized by blending natural raw materials having a bactericidal effect. 102. The supplement according to claim 101, wherein the natural ingredients include plant extracts. 103. The supplement of claim 102, wherein the plant extract comprises grapefruit extract or tea extract. 104. The supplement of claim 103, wherein said grapefruit extract comprises grapefruit seed extract. 104. The supplement according to claim 103, wherein the tea extract contains tea catechins. A cosmetic product characterized by containing a natural raw material having a bactericidal effect. 107. Cosmetics according to claim 106, wherein the natural ingredients comprise plant extracts. 108. Cosmetics according to claim 107, characterized in that the plant extract comprises a grapefruit extract or a tea extract. 109. Cosmetics according to claim 108, characterized in that said grapefruit extract comprises grapefruit seed extract. 109. Cosmetics according to claim 108, wherein the tea extract contains tea catechins. A medicine characterized by blending a natural raw material having a bactericidal effect. 112. The medicament according to claim 111, wherein said natural source material comprises a plant extract. 113. The medicament according to claim 112, wherein the plant extract comprises grapefruit extract or tea extract. 114. The medicament according to claim 113, wherein said grapefruit extract comprises grapefruit seed extract. 114. The pharmaceutical according to claim 113, wherein the tea extract contains tea catechins.

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