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WO2022126976A1 - Désinfectant spécial pour la viande, et son procédé de préparation - Google Patents

Désinfectant spécial pour la viande, et son procédé de préparation Download PDF

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Publication number
WO2022126976A1
WO2022126976A1 PCT/CN2021/090797 CN2021090797W WO2022126976A1 WO 2022126976 A1 WO2022126976 A1 WO 2022126976A1 CN 2021090797 W CN2021090797 W CN 2021090797W WO 2022126976 A1 WO2022126976 A1 WO 2022126976A1
Authority
WO
WIPO (PCT)
Prior art keywords
disinfectant
parts
quaternary ammonium
meat
ammonium salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2021/090797
Other languages
English (en)
Chinese (zh)
Inventor
赵建利
孙红霞
张子衿
齐建军
陈姝羽
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Reward Homecare Chemical Co Ltd
Original Assignee
Beijing Reward Homecare Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Reward Homecare Chemical Co Ltd filed Critical Beijing Reward Homecare Chemical Co Ltd
Publication of WO2022126976A1 publication Critical patent/WO2022126976A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/02—Amines; Quaternary ammonium compounds
    • A01N33/12—Quaternary ammonium compounds

Definitions

  • the invention relates to the technical field of disinfectant, in particular to a special disinfectant applied to meat food and a preparation method thereof.
  • Quaternary ammonium salts are an important class of cationic surfactants, which are prepared by the reaction of tertiary amines and alkylating agents. Such compounds are widely used. It can be used as agricultural bactericide, aquaculture bactericidal disinfectant, livestock and poultry house disinfectant, circulating water bactericidal algaecide and medical bactericidal disinfectant.
  • Its disinfection and sterilization mechanism is that quaternary ammonium salt cations aggregate on the cell wall under the action of electrostatic force, hydrogen bonding force and surfactant molecules, resulting in the extravasation of important protein molecules and nutrients in the bacteria, and blocking the process of bacterial respiration and glucose metabolism, thereby Produces a chamber resistance effect, resulting in the denaturation of bacterial proteins, inhibiting bacterial growth, and causing bacterial death.
  • Ammonium salt alkyl changes the permeability of bacterial cell membrane by combining with bacterial surface protein molecules, and then lysis occurs, destroys bacterial cell structure, causes bacterial death, and achieves the effect of sterilization.
  • the purpose of the present invention is to solve the problem of disinfection of meat food, and to provide a special disinfectant for meat food, which has the advantages of rapid sterilization, good disinfection effect, hygienic safety, no toxic and side effects, good stability, simple preparation, easy operation, and good disinfection effect on meat. There is no impact on the surface of the class to ensure the quality and safety of the meat.
  • a special disinfectant for meat food characterized in that, the composition and the parts by mass thereof are as follows:
  • the single long-chain quaternary ammonium salt is dodecyl dimethyl benzyl ammonium chloride, tetradecyl dimethyl benzyl ammonium chloride, hexadecyl dimethyl benzyl ammonium chloride One or more of ammonium.
  • the quaternary ammonium salt of the double long chain is one or more of bis-octyl dimethyl ammonium chloride, bis-decyl dimethyl ammonium chloride and octyl decyl dimethyl ammonium chloride .
  • the disinfecting solution contains 2.3 parts by mass of dodecyl dimethyl benzyl ammonium chloride, 3.4 parts by mass of bisdecyl dimethyl ammonium chloride and 94.3 parts by mass of deionized water.
  • Another aspect of the present invention also relates to a method for using the aforementioned special disinfectant for meat food, characterized in that the article to be disinfected is sprayed with the special disinfectant for meat food, and then the article to be disinfected is placed in a dry place. The bacteria environment is kept for a period of time, and then the special disinfectant for meat food on the object to be disinfected is washed out.
  • the period of time is 5 minutes to 10 minutes.
  • the item to be sterilized is a meat surface.
  • the disinfectant of the invention is composed of single long-chain quaternary ammonium salt and double long-chain quaternary ammonium salt.
  • the single-chain quaternary ammonium salt can only kill certain bacterial propagules and lipophilic viruses.
  • Ammonium salts can kill a variety of microorganisms, including bacterial propagules, certain fungi and viruses.
  • the invention selects high-efficiency quaternary ammonium salt components and adopts scientific proportioning, which has fast sterilization, good disinfection effect, hygienic safety, no toxic and side effects, good stability, and no influence on the surface of meat, so as to ensure the quality and safety of meat.
  • the disinfectant of the present invention has simple components, can only be composed of single long chain/double long chain quaternary ammonium salt and deionized water, is convenient to prepare, and is beneficial to large-scale production and promotion.
  • a special disinfectant for meat food, the components and the mass parts thereof are:
  • Test strain Staphylococcus aureus (ATCC6538), provided by the General Microbiology Center of the China Society for the Collection and Management of Microorganisms.
  • Neutralizer DE broth of 3g/L lecithin and 3% Tween-80.
  • Disinfectants prepared in Examples 1-3 of the present invention Disinfectants prepared in Examples 1-3 of the present invention.
  • Carrier for infection the surface of pork belly.
  • TSA Tryptone Soy Agar
  • Test method Mark two 25cm 2 bacteria-contaminated areas on the surface of pork belly with a specification plate, apply the bacterial suspension evenly to the bacteria-contaminated areas, and carry out the test after natural drying. Wet a sterile cotton swab in a test tube containing 5 mL of diluent, and smear and sample the infected area without disinfection as a positive control group. According to the method of use described in the manual, spray the infected pork belly with disinfectant for 5 minutes. Wet a sterile cotton swab in the sample containing 5 mL of neutralizing agent, and smear the infected area after disinfection. test group.
  • the present invention is a special disinfectant for meat food. Compared with the existing disinfectants such as sodium hypochlorite and hydrogen peroxide, the disinfectants of Examples 1-3 have a good disinfection effect.
  • the existing volatile and oxidative disinfection components such as sodium hypochlorite and hydrogen peroxide have poor disinfection effect on the surface of meat, and easily affect the appearance and quality of meat.
  • the disinfectants of Examples 1-3 have good disinfection effects, and the quaternary ammonium salt compound disinfectant of Example 2 has the lowest sterilization cost, which is more conducive to popularization and use.
  • Acute oral toxicity test (mice): The acute oral LD 50 of male and female mice is greater than 5000mg/kg body weight, which is actually non-toxic.
  • Mouse bone marrow polychromatic erythrocyte micronucleus test no micronucleus effect.
  • the acute oral toxicity test LD 50 of male and female mice of special disinfectant for meat food is more than 5000mg/kg body weight, which is actually non-toxic according to the acute toxicity grading standard. It meets the requirements of the 2002 edition of the "Technical Specification for Disinfection".
  • the composite double-chain quaternary ammonium salt disinfectant of the present invention has rapid sterilization, good disinfection effect, sanitation and safety, no toxic and side effects, good stability, no influence on the surface of meat, guarantees the quality and safety of meat, and is suitable for Large-scale promotion of applications.
  • the special disinfectant for meat food of the present invention everyone can eat assured meat.
  • Example 2 of the present invention is significantly better than other embodiments.
  • the preparation process is simple and the use is convenient. While achieving the disinfection effect, it can effectively reduce the use of quaternary ammonium salts, and greatly reduce the residue of disinfectant, so as to achieve non-toxic and non-irritating odor.

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Dentistry (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)

Abstract

La présente invention concerne un désinfectant spécial pour la viande, comprenant les principaux constituants actifs suivants en parties en masse : de 0,5 à 5 parties d'un sel d'ammonium quaternaire à simple chaîne, de 0,5 à 7 parties d'un sel d'ammonium quaternaire à double chaîne, et de 88 à 99 parties d'eau désionisée. Selon la présente invention, un bon effet de stérilisation peut être atteint sans nécessité d'ajouter un agent stabilisant et d'autres promoteurs. Le présent désinfectant spécial pour la viande est capable de tuer les micro-organismes sur la surface de la viande, ne présente pas d'effet d'oxydation sur la surface de la viande, présente une biodégradabilité élevée, est hygiénique et sans danger, ne présente pas d'effets secondaires toxiques, présente une bonne stabilité, et convient à l'application à grande échelle.
PCT/CN2021/090797 2020-12-18 2021-04-29 Désinfectant spécial pour la viande, et son procédé de préparation Ceased WO2022126976A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202011502989.8A CN112640902A (zh) 2020-12-18 2020-12-18 一种肉类食品专用消毒液及其制备方法
CN202011502989.8 2020-12-18

Publications (1)

Publication Number Publication Date
WO2022126976A1 true WO2022126976A1 (fr) 2022-06-23

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PCT/CN2021/090797 Ceased WO2022126976A1 (fr) 2020-12-18 2021-04-29 Désinfectant spécial pour la viande, et son procédé de préparation

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CN (1) CN112640902A (fr)
WO (1) WO2022126976A1 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112640902A (zh) * 2020-12-18 2021-04-13 北京洛娃日化有限公司 一种肉类食品专用消毒液及其制备方法

Citations (7)

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CN102246753A (zh) * 2011-05-09 2011-11-23 张家港耐尔纳米科技有限公司 一种复合季铵盐消毒液
CN102349574A (zh) * 2011-09-20 2012-02-15 中国科学院华南植物园 一种用季铵盐保鲜荔枝的方法
CN104336014A (zh) * 2014-11-05 2015-02-11 武汉航科天地科技有限公司 复方双长链季铵盐消毒剂
CN106818741A (zh) * 2016-12-30 2017-06-13 杭州易路医疗器械有限公司 复合双链季铵盐消毒液及其使用方法和应用
CN108617650A (zh) * 2018-07-13 2018-10-09 北京安洁泰科技有限公司 一种复合杀菌剂及其制备方法
CN112022732A (zh) * 2020-09-18 2020-12-04 杭州健驰医疗科技有限公司 一种免洗手消毒液及其制备方法
CN112640902A (zh) * 2020-12-18 2021-04-13 北京洛娃日化有限公司 一种肉类食品专用消毒液及其制备方法

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CN112618525A (zh) * 2020-12-18 2021-04-09 上海海禾医疗科技有限公司 一种快速灭活冠状病毒的消毒液

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CN102246753A (zh) * 2011-05-09 2011-11-23 张家港耐尔纳米科技有限公司 一种复合季铵盐消毒液
CN102349574A (zh) * 2011-09-20 2012-02-15 中国科学院华南植物园 一种用季铵盐保鲜荔枝的方法
CN104336014A (zh) * 2014-11-05 2015-02-11 武汉航科天地科技有限公司 复方双长链季铵盐消毒剂
CN106818741A (zh) * 2016-12-30 2017-06-13 杭州易路医疗器械有限公司 复合双链季铵盐消毒液及其使用方法和应用
CN108617650A (zh) * 2018-07-13 2018-10-09 北京安洁泰科技有限公司 一种复合杀菌剂及其制备方法
CN112022732A (zh) * 2020-09-18 2020-12-04 杭州健驰医疗科技有限公司 一种免洗手消毒液及其制备方法
CN112640902A (zh) * 2020-12-18 2021-04-13 北京洛娃日化有限公司 一种肉类食品专用消毒液及其制备方法

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PENG HUIJUAN, SANG JUN; WANG CHUNHUA; LIN WEI: "Antibacterial Activity of Quaternary Ammonium Salts and Preservative Effect on Raw Skin", CHINA LEATHER, vol. 44, no. 09, 3 May 2015 (2015-05-03), XP055943342 *

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