[go: up one dir, main page]

WO2022118845A1 - Cathéter - Google Patents

Cathéter Download PDF

Info

Publication number
WO2022118845A1
WO2022118845A1 PCT/JP2021/043890 JP2021043890W WO2022118845A1 WO 2022118845 A1 WO2022118845 A1 WO 2022118845A1 JP 2021043890 W JP2021043890 W JP 2021043890W WO 2022118845 A1 WO2022118845 A1 WO 2022118845A1
Authority
WO
WIPO (PCT)
Prior art keywords
tip
catheter
end side
tube
base
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2021/043890
Other languages
English (en)
Japanese (ja)
Inventor
健一 堀場
大 冨田
春佳 杉村
光則 吉川
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Terumo Corp
Original Assignee
Terumo Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Terumo Corp filed Critical Terumo Corp
Publication of WO2022118845A1 publication Critical patent/WO2022118845A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/06—Body-piercing guide needles or the like

Definitions

  • the present invention relates to a catheter having an intermediate opening having a tip tube and a linear shaft connected to the tip tube and extending from the tip tube to the proximal side.
  • a guiding catheter is used to guide a therapeutic catheter (balloon catheter, stent indwelling catheter, etc.) for inserting into a biological lumen such as a blood vessel for treatment or diagnosis to a target site.
  • a therapeutic catheter balloon catheter, stent indwelling catheter, etc.
  • PTCA percutaneous coronary angioplasty
  • a guide wire for a guiding catheter is inserted into the artery through the skin of the wrist or thigh and into the entrance of the coronary artery. Reach.
  • the guiding catheter is then inserted into the artery along the guide wire, followed by the removal of the guiding catheter guide wire and engagement with the coronary artery ostium.
  • a guide wire for a therapeutic catheter is inserted into the lumen of the guiding catheter to pass through the lesion in the coronary artery.
  • the balloon catheter is inserted along the thinner guide wire for the therapeutic catheter, the tip of the balloon catheter is projected from the opening of the tip of the guiding catheter, and the inside of the coronary artery is advanced to the periphery along the guide wire that has passed through the lesion. , Place a balloon in the lesion and inflate the balloon for treatment.
  • a guide extension catheter After engaging the tip of the guiding catheter to a predetermined site (eg, coronary artery ostium), a guide extension catheter is used to smoothly advance the therapeutic catheter through the curved or bent coronary artery from the opening of the guiding catheter tip to the lesion. May be used. That is, the guide extension catheter can be inserted closer to the lesion than the guiding catheter, and can further provide a stable backup force to the therapeutic catheter.
  • a predetermined site eg, coronary artery ostium
  • the guide extension catheter has a tip tube that moves through the lumen of the guiding catheter and can protrude from the tip opening of the guiding catheter to the tip side, and a linear shape that is connected to the tip tube and extends from the tip tube to the proximal side.
  • the length of the guide wire protruding toward the proximal end side of the guiding catheter is longer than the length of the tubular portion of the guide extension catheter. Since the guide extension catheter has a linear shaft, the length of the tubular portion can be shortened, so that it is not necessary to use a guide wire longer than necessary, and the procedure is facilitated.
  • Patent Document 1 discloses a catheter having a hook-shaped portion having a U-shaped or U-shaped tip of a linear shaft and having an intermediate opening connected to the tip tube.
  • the shaft base and the tip tube are disclosed. Since the inner shaft is coaxial, the shaft may come off from the tip tube when the hand of the catheter having an intermediate opening is pulled.
  • the present invention has been made to solve the above-mentioned problems, and has an intermediate opening capable of effectively exerting a pushing force and a rotational force and preventing the tip tube and the linear shaft from separating during surgery.
  • the purpose is to provide a catheter.
  • a catheter having an intermediate opening that achieves the above object is a catheter having an intermediate opening having a distal tube and a linear shaft extending from the distal tube toward the proximal end, and the linear shaft is shaped.
  • the tip shape portion has a tip shape portion and a base portion extending from the tip shape portion to the base end side, and the tip shape portion has an intermediate straight line portion extending linearly from the base portion to the tip end side and the intermediate straight line portion.
  • a semi-circular portion that is arranged on the tip side of the portion and bends so as to draw a substantially half-circle, and an end that is opposite to the side where the intermediate straight portion of the semi-circular portion is arranged extends linearly from the end portion to the base end side.
  • the intermediate straight line portion has an existing tip straight line portion, and at least a part thereof is inclined with respect to an extension line extending from the base portion to the tip end side, and the semicircular portion is arranged on the extension line.
  • the tip straight portion is characterized in that it is arranged on the opposite side of the intermediate straight portion with the extension line interposed therebetween.
  • the tip straight portion and the intermediate straight portion are arranged on both sides of the extension line extending from the base, so that the force can be efficiently transmitted from the linear shaft to the tip tube. Can be done. Therefore, when the surgeon operates the linear shaft located outside the body, the catheter having this intermediate opening can effectively apply a pushing force and a rotational force to the tip tube, and the tip can be applied during the operation. It is possible to prevent the tube and the linear shaft from separating.
  • a catheter having an intermediate opening that achieves the above object is a catheter having an intermediate opening having a distal tube and a linear shaft extending from the distal tube toward the proximal end, wherein the distal tube is a distal end. It is a tubular body having a lumen penetrating from to the proximal end, and includes a tubular portion arranged on the distal end side and a semi-tubular portion arranged on the proximal end side of the tubular portion, and the linear shaft has a shape.
  • the linear shaft has an attached tip-shaped portion and a base portion extending from the tip-shaped portion to the proximal end side, and the linear shaft has at least a part embedded in the layer of the semi-tube portion and is tubular.
  • the tip tube Embedded in the layer on the base end side of the portion, the tip tube has a reinforcing body formed by winding or braiding at least one wire, and the tip shaped portion is from the base to the tip.
  • An intermediate straight line portion extending linearly to the side, a semicircular portion arranged on the tip end side of the intermediate straight line portion and bending so as to draw a substantially half circle, and the intermediate straight line portion of the semicircular portion are arranged. It has a tip straight portion extending linearly from the end on the opposite side to the base end side, and the semicircular portion is arranged at a position overlapping with the reinforcing body in the axial direction of the tip tube. It is characterized by that.
  • the tubular part and the semi-tube part of the tip tube are fixed to the linear shaft, so that the catheter having this intermediate opening has an effect of pushing force and rotational force on the tip tube. It is possible to prevent the tip tube and the linear shaft from separating during the operation, and the change in physical properties from the tubular portion to the hemitube portion of the tip tube is reduced.
  • a catheter having an intermediate opening having a distal tube and a linear shaft extending from the distal tube toward the proximal end.
  • the tip tube has a shaped tip shape portion and a base portion extending from the tip shape portion to the base end side, and the tip tube is a reinforcing body formed by winding or braiding at least one wire rod.
  • the tip shape portion has an intermediate straight line portion extending linearly from the base portion to the tip end side, and a semicircular portion arranged on the tip end side of the intermediate straight line portion and curved so as to draw a substantially half circle.
  • the tip straight portion extending linearly from the end opposite to the side on which the intermediate straight portion of the semicircle is arranged to the proximal end side, and the semicircle portion is the tip tube. It is characterized in that it is arranged at a position overlapping with the reinforcing body in the axial direction of the above, and the end portion of the tip straight line portion on the proximal end side is arranged on the proximal end side of the reinforcing body.
  • the catheter having the intermediate opening configured as described above is that the semicircle overlaps the reinforcement and the straight tip extending from the semicircle reaches the proximal side beyond the reinforcement. Therefore, the range in which the straight tip portion overlaps with the reinforcing body becomes wide, and it is easy to transmit the force from the linear shaft to the reinforcing body for imparting strength to the tip tube. Therefore, the catheter having an intermediate opening can efficiently transmit the force from the linear shaft to the tip tube. Therefore, when the operator operates the linear shaft located outside the body, the catheter having this intermediate opening can effectively apply a pushing force and a rotational force to the tip tube, and the tip tube can be effectively applied during the operation. And the linear shaft can be prevented from separating.
  • the linear shaft may have at least one tapered portion whose outer diameter is tapered toward the tip side.
  • the semicircular portion may have a tapered portion or may have a constant diameter in order to control the overall physical characteristics of the catheter having an intermediate opening.
  • the linear shaft has a first straight portion having a constant outer diameter, a first tapered portion having a reduced outer diameter, a second straight portion having a constant outer diameter, and an outer side from the proximal end side to the distal end side. It has a second tapered portion whose diameter is reduced and a third straight portion having a constant outer diameter.
  • the first straight portion forms the base portion
  • the first tapered portion is a base portion and an intermediate straight portion.
  • a portion including a boundary is formed, and the second straight line portion, the second tapered portion, and a part of the proximal end side of the third straight line portion form the intermediate straight line portion, and other than the third straight line portion.
  • the site may form the semi-circular portion and the tip straight portion.
  • the linear shaft has a flexible structure in which the rigidity is gradually reduced toward the tip side, so that it is possible to impart flexibility to the tip portion and to impart high pushability to the base end portion.
  • the tip shape portion may have a smaller outer diameter than the base portion and may be constant.
  • the tip-shaped portion has a less rigid structure than the base portion and has a flexible structure, so that it is possible to impart flexibility to the tip portion and to impart high pushability to the base end portion.
  • the axis of the tip shape portion may be three-dimensionally arranged beyond the same plane.
  • the tip-shaped portion may have a barb portion that protrudes in a direction away from the outer peripheral surface of the tip-shaped portion and in a direction connected to the base portion.
  • the barb may be engageable with a reinforcing body formed on the tip tube by winding or braiding at least one wire. As a result, it is possible to firmly prevent the return portion from being caught by the reinforcing body of the tip tube and the linear shaft from coming off the tip tube.
  • the catheter having the intermediate opening projects the tip of the therapeutic catheter from the tip opening of the guiding catheter to guide the therapeutic catheter to be inserted into the guiding catheter, and the tip of the therapeutic catheter is inserted into the coronary artery along the therapeutic catheter.
  • It may be a guide extension catheter for arranging a treatment portion for performing treatment provided on the treatment catheter to the periphery.
  • the catheter having the intermediate opening projects the tip of the therapeutic catheter from the tip opening of the guiding catheter to guide the therapeutic catheter to be inserted into the guiding catheter, and the tip of the therapeutic catheter is inserted into the coronary artery along the therapeutic catheter.
  • It may be a rapid exchange type dilator that is provided in the therapeutic catheter and is inserted into a guide extension catheter for arranging a treatment portion for treatment in the lesion portion.
  • FIG. 3 is a plan view showing a guide extension catheter, a dilator, and a guiding catheter, which are catheters having an intermediate opening according to the present embodiment. It is a figure which shows the guide extension catheter, (A) is a side view, (B) is a plan view, (C) is a partially enlarged view of a linear shaft. It is a figure which shows the guide extension catheter, (A) is the sectional view along the line AA of FIG. 2, (B) is the sectional view along the line BB of FIG. It is sectional drawing along the C line.
  • FIG. 1 It is a figure which shows the dilator, (A) is a side view, (B) is a plan view, (C) is a partially enlarged view of a dilator linear shaft. Is. It is sectional drawing which follows the DD line of FIG. It is a side view which shows the catheter assembly which assembled the dilator to the guide extension catheter. It is a figure of the catheter which has the intermediate opening which shows the 1st modification, (A) is the side view, (B) is the side view which shows through the tip tube. It is a figure of the catheter having an intermediate opening which shows the 2nd modification, (A) is a plan view, (B) is a front view which shows through the tip tube.
  • the side of the device to be inserted into the blood vessel is referred to as the "tip side”, and the side to be operated is referred to as the "base end side”.
  • the catheter having an intermediate opening is inserted into a guiding catheter 100 having a tip soft tip 100A, protrudes from the tip opening 101 of the guiding catheter 100, and guides the therapeutic catheter.
  • a guide extension catheter 10 used to extend the tube to the distal side from the guiding catheter 100.
  • a rapid exchange type dilator 50 can be inserted into the guide extension catheter 10.
  • the guide extension catheter 10 includes a tubular tip tube 20 and a linear shaft 30 connected to the tip tube 20 and extending from the tip tube 20 to the proximal end side.
  • the tip tube 20 can move in the lumen of the guiding catheter 100 and project from the tip opening 101 of the guiding catheter 100 toward the tip side. Thereby, the tip tube 20 provides a continuous lumen from the guiding catheter 100. That is, in the procedure, the tip tube 20 of the guide extension catheter 10 can be inserted closer to the lesion than the guiding catheter 100 to provide a stable backup to the therapeutic catheter.
  • the tip tube 20 is a tubular body having a lumen penetrating from the tip to the proximal end, and includes a tubular portion 21 arranged on the distal end side and a half-tube portion 22 arranged on the proximal end side of the tubular portion 21. ing.
  • the tubular portion 21 is formed into a circular tubular portion by being provided with a material within a range of 360 degrees in the circumferential direction.
  • the half-pipe portion 22 is formed in the shape of a half-pipe by being provided with a material within a range of approximately 180 degrees in the circumferential direction.
  • the angle range in which the material of the half-pipe portion 22 is provided is not particularly limited as long as it is less than 360 degrees, and may be, for example, less than 180 degrees. Further, the half-pipe portion 22 may not be provided.
  • the length of the tubular portion 21 in the axial direction is not particularly limited, but is, for example, 200 mm to 400 mm.
  • the length of the half-pipe portion 22 in the axial direction is not particularly limited, but is, for example, 5 mm to 200 mm.
  • the inner diameter of the tip tube 20 is not particularly limited, but is, for example, 1.3 mm to 1.5 mm.
  • the outer diameter of the tip tube 20 is not particularly limited, but is, for example, 1.55 mm to 1.75 mm.
  • the rigidity of the tip tube 20 gradually or gradually decreases from the base end side to the tip end side.
  • the tip tube 20 has a flexible structure in which the rigidity is reduced toward the tip side, so that it is possible to impart flexibility to the tip portion and to impart high pushability to the base end portion.
  • the rigidity of the tip tube 20 does not have to change from the proximal end side to the distal end side.
  • the tip tube 20 has a tip 21A at the forefront, which is formed of a flexible material such as polyurethane.
  • the tip tube 20 includes an inner layer 23, a reinforcing body 24, a middle layer 25, an outer layer 26, a tip marker 27, and a base end marker 28.
  • the inner layer 23 is a layer that forms the inner peripheral surface of the tubular portion 21 and the half-tube portion 22 of the tip tube 20.
  • the inner layer 23 is preferably formed of a low friction material so that the guide wire, the therapeutic catheter, the dilator 50, and the like can easily slide inside.
  • the low-friction material is, for example, a fluororesin such as PTFE (polytetrafluoroethylene) or PFA (tetrafluoroethylene / perfluoroalkoxyethylene copolymer) or a silicon resin, but is not limited thereto.
  • the thickness of the inner layer 23 is not particularly limited, but is, for example, 0.0001 mm to 0.1 mm, preferably 0.005 mm to 0.05 mm, and more preferably 0.01 mm to 0.03 mm.
  • the reinforcing body 24 is formed by a coil wound spirally or a plurality of braided blades to reinforce the tubular portion 21 of the tip tube 20.
  • the coil and blade are wire rods made of a metal material such as stainless steel, and the cross-sectional shape of the wire rod is a shape such as a circle, an ellipse, an oval, or a rectangle, and the diameter, width, and thickness of the wire rod are not particularly limited. , Set as appropriate.
  • the crossing angle between the long axis and the wire rod is not particularly limited, and may be appropriately set and may be constant or change along the long axis direction.
  • the reinforcing body 24 When the reinforcing body 24 is formed by a blade, the number of picks with one of the stitches as a pick (pick), the number of wires included in one pick (number of ends), and the number of picks in one round.
  • the number of spins which is the number of numbers, is appropriately set.
  • the shape and dimensions of the reinforcing wire may be different depending on the winding direction.
  • the wires forming the coils or blades of the reinforcing body 24 may be arranged at a sparse pitch with gaps or may be arranged at a close pitch without gaps.
  • the reinforcing body 24 can be a contrast marker that improves contrast when the tungsten wires are arranged at a close pitch.
  • the middle layer 25 is a layer surrounding the inner layer 23 of the tubular portion 21 of the tip tube 20, the inner layer 23 of the half-pipe portion 22, and the outer peripheral surface of the reinforcing body 24.
  • the middle layer 25 is joined to the inner layer 23 to the extent that the reinforcing body 24 is not provided.
  • the constituent material of the middle layer 25 is not particularly limited, but for example, various heats such as styrene-based, polyolefin-based, polyurethane-based, polyester-based, polyamide-based, polybutadiene-based, transpolyisoprene-based, fluororubber-based, and chlorinated polyethylene-based.
  • the thickness of the middle layer 25 is not particularly limited, but is, for example, 0.0001 mm to 0.1 mm, preferably 0.005 mm to 0.05 mm, and more preferably 0.01 mm to 0.03 mm.
  • the outer layer 26 is a layer that forms the outer peripheral surfaces of the tubular portion 21 and the half-tube portion 22 of the tip tube 20.
  • the outer layer 26 surrounds the outer peripheral surface of the middle layer 25 of the tubular portion 21 and the half-pipe portion 22.
  • the outer layer 26 further surrounds the outer peripheral surfaces of the tip marker 27 and the proximal marker 28 provided on the tubular portion 21.
  • the outer layer 26 is fixed with the linear shaft 30 sandwiched between the outer layer 26 and the middle layer 25. Therefore, the linear shaft 30 does not come into direct contact with the reinforcing body 24.
  • the linear shaft 30 and the reinforcing body 24 are made of a metal material, they are slippery and prone to wear when they come into contact with each other.
  • the outer layer 26 has an outer layer fixing portion 29 for fixing the linear shaft 30.
  • the outer layer fixing portion 29 projects radially outward in a cross section orthogonal to the axis of the tip tube 20. Therefore, the outer layer 26 does not become too thin in the range where the linear shaft 30 is arranged inside. Therefore, the strength of the tip tube 20 can be improved, the linear shaft 30 can be prevented from coming off from the tip tube 20, the linear shaft 30 does not need to be too thin, and the pushability of the guide extension catheter 10 can be improved.
  • the outer layer fixing portion 29 does not have to protrude outward in the radial direction.
  • outer layer 26 and the middle layer 25 may use the same material, or may use different colors or different hardnesses.
  • the constituent material of the outer layer 26 is not particularly limited, and is, for example, various thermoplastics such as styrene-based, polyolefin-based, polyurethane-based, polyester-based, polyamide-based, polybutadiene-based, transpolyisoprene-based, fluororubber-based, and chlorinated polyethylene-based.
  • various thermoplastics such as styrene-based, polyolefin-based, polyurethane-based, polyester-based, polyamide-based, polybutadiene-based, transpolyisoprene-based, fluororubber-based, and chlorinated polyethylene-based.
  • examples thereof include elastomers, polyether ketones, polyimides, and the like, and one or a combination of two or more of these (polymer alloy, polymer blend, laminate, etc.) can be used.
  • polyester elastomers, polyamide elastomers, and the like can be preferably used.
  • the thickness of the outer layer 26 is not particularly limited, but is, for example, 0.0001 mm to 0.1 mm, preferably 0.005 mm to 0.05 mm, and more preferably 0.01 mm to 0.03 mm. Is.
  • the outer peripheral surface of the outer layer 26 may be coated with a lubricating material in order to improve the permeability with blood vessels and the inner wall surface of the guiding catheter 100.
  • Lubricating materials include, for example, epoxy group-containing monomers such as glycidyl acrylate, glycidyl methacrylate, 3,4-epoxycyclohexylmethyl acrylate, 3,4-epoxycyclohexylmethylmethacrylate, ⁇ -methylglycidylmethacrylate, and allylglycidyl ether, and N.
  • epoxy group-containing monomers such as glycidyl acrylate, glycidyl methacrylate, 3,4-epoxycyclohexylmethyl acrylate, 3,4-epoxycyclohexylmethylmethacrylate, ⁇ -methylglycidylmethacrylate, and allylglycidyl ether, and N.
  • hydrophilic monomers such as methyl acrylamide, N, N-dimethylacrylamide, acrylamide
  • (co) polymer composed of the above hydrophilic monomers cellulose such as hydroxypropyl cellulose, carb
  • High polymer substances polysaccharides, polyvinyl alcohol, methyl vinyl ether-maleic anhydride copolymer, water-soluble polyamide, poly (2-hydroxyethyl (meth) crylate), polyethylene glycol, polyacrylamide, polyvinylpyrrolidone and the like can be mentioned. It is preferably a hydrophilic lubricating polymer such as a polyacrylamide copolymer containing acrylamide, and may be a hydrophobic lubricating polymer such as a fluororesin.
  • the tip marker 27 and the base marker 28 contain an X-ray opaque metal that can be visually recognized under fluoroscopy.
  • the tip marker 27 and the proximal marker 28 are, for example, ring-shaped members, but may be members having a C-shaped cross section, coils, or the like.
  • X-ray opaque metals are, for example, gold, platinum, silver, bismuth, tungsten, or alloys of two or more of these (eg, platinum-tungsten), barium sulfate, or alloys with other metals (eg, gold).
  • -Iridium, platinum-iridium, platinum-nickel and the like.
  • the tip marker 27 is sandwiched between the middle layer 25 and the outer layer 26 at the tip of the tubular portion 21.
  • the position where the tip marker 27 is arranged is not limited to between the middle layer 25 and the outer layer 26, and may be arranged, for example, between the inner layer 23 and the middle layer 25 or outside the outer layer 26.
  • the proximal end marker 28 is placed between the middle layer 25 and the outer layer 26 at the proximal end portion of the tubular portion 21.
  • the position where the proximal end marker 28 is arranged is not limited to between the middle layer 25 and the outer layer 26, and may be arranged, for example, between the inner layer 23 and the middle layer 25 or outside the outer layer 26.
  • the linear shaft 30 is a flexible wire, and may be a round wire, a flat wire, or an arc wire, but a round wire is preferable, and the linear shaft 30 is connected to the tip tube 20 and extends from the tip tube 20 to the base end side.
  • the linear shaft 30 includes a linear base portion 31 and a tip-shaped portion 32 arranged and shaped on the tip end side of the base portion 31. Since the base 31 is flexible and bends flexibly, it does not have to be linear at all times.
  • an intermediate straight line portion 33 extending from the base portion 31 to the tip end side, a semicircular portion 34 arranged on the tip end side of the intermediate straight line portion 33, and an intermediate straight line portion 33 from the semicircular portion 34 are arranged. It is provided with a tip straight portion 35 extending to the opposite side to the other side.
  • the intermediate straight portion 33 reaches from the proximal end surface of the half-pipe portion 22 to the proximal end portion of the tubular portion 21. Therefore, the tip of the intermediate straight line portion 33 is located at the tubular portion 21.
  • the intermediate straight line portion 33 is located on the axis of the base portion 31 and is inclined at a minute angle exceeding 0 degrees with respect to the extension line L1 extending from the base portion 31 toward the tip end side. Therefore, the intermediate straight line portion 33 is arranged so as to be offset to one side from the extension line L1.
  • the base end of the intermediate straight line portion 33 may be located closer to the base end side than the base end of the half pipe portion 22, or may be located on the tip end side of the half pipe portion 22.
  • the starting point at which the intermediate straight line portion 33 is located on the axis of the base portion 31 and is inclined with respect to the extension line L1 extending from the base portion 31 toward the tip side may be in the half-pipe portion 22 or in the tubular portion 21. You may.
  • the semicircular portion 34 is bent by changing the direction by about 180 degrees so as to draw a substantially semicircle at the base end portion of the tubular portion 21.
  • the semicircular portion 34 is arranged so as to intersect the extension line L1.
  • the semicircular portion 34 does not have to exactly intersect the extension line.
  • the semicircular portion 34 is arranged at a position overlapping the reinforcing body 24 in the axial direction of the tip tube 20. That is, both the semicircular portion 34 and the reinforcing body 24 are provided within a predetermined range in the axial direction of the tip tube 20.
  • the tip straight portion 35 extends from the end portion of the tubular portion 21 opposite to the side in contact with the intermediate straight portion 33 to the proximal end side.
  • the tip straight portion 35 is substantially parallel to the extension line L1, but does not have to be strictly parallel.
  • An extension line L1 is arranged between the intermediate straight line portion 33 and the tip straight line portion 35.
  • the intermediate straight line portion 33, the semicircular portion 34, and the tip straight line portion 35 are arranged on the same plane.
  • the end portion 36 located on the side opposite to the side in contact with the semicircle portion 34 of the tip straight portion 35 is located on the tubular portion 21.
  • the terminal portion 36 may be located at the half-pipe portion 22.
  • the end portion 36 is arranged on the proximal end side of the reinforcing body 24 in the axial direction of the tip tube 20.
  • the tip shape portion 32 may be engaged so as to be hooked on the wire rod forming the reinforcing body 24.
  • the state in which the tip shape portion 32 is caught by the wire rod forming the reinforcing body 24 is, for example, the state in which the tip shape portion 32 is from the inner peripheral surface side to the outer peripheral surface side or from the outer peripheral surface side to the inner peripheral surface side of the reinforcing body 24.
  • a state in which the wire rods constituting the reinforcing body 24 are passed through the gaps thereof can be mentioned. This makes it possible to prevent the linear shaft 30 from falling off from the tip tube 20.
  • the radius of curvature of the semicircular portion 34 does not have to be constant, and the direction of the semicircular portion or the semicircular portion may exceed 180 degrees, and conversely, it may not be less than 180 degrees.
  • the linear shaft 30 may be coated with a low friction material so that it can slide with the inner wall surface of the guiding catheter 100 with low friction.
  • the low friction material is, for example, a fluororesin or a silicon resin, but is not limited thereto.
  • the linear shaft 30 may be coated with a lubricating material in whole or in at least a part in order to improve the slidability with the inner wall surface of the guiding catheter 100.
  • the linear shaft 30 has a first straight line portion 40 having a constant outer diameter and a first tapered portion 41 having a decreasing outer diameter from the proximal end side to the distal end side. It has a second straight line portion 42 having a constant outer diameter, a second tapered portion 43 having a reduced outer diameter, and a third straight line portion 44 having a constant outer diameter.
  • the first straight line portion 40 forms the base portion 31.
  • the first tapered portion 41 forms a portion including the boundary between the base portion 31 and the intermediate straight portion 33.
  • the second straight line portion 42, the second tapered portion 43, and a part of the third straight line portion 44 on the proximal end side form an intermediate straight line portion 33.
  • the third straight portion 44 forms a semicircular portion 34 and a tip straight portion 35.
  • the tip straight portion 35, the semicircle portion 34 and the intermediate straight portion 33 may be on the tip side of the second tapered portion 43, that is, the tip shape portion 32 may have a smaller outer diameter than the base 31 and may be constant. ..
  • the linear shaft 30 is connected to the tip tube 20 after the tip shape portion 32 is shaped into a predetermined shape.
  • the outer diameter of the linear shaft 30 is not particularly limited, but is, for example, 0.05 mm to 1 mm.
  • the length of the base 31 of the linear shaft 30 in the axial direction is not particularly limited, but is, for example, 1100 mm to 1300 mm.
  • the constituent material of the linear shaft 30 is not particularly limited, but for example, stainless steel, nickel-titanium alloy, or the like can be preferably used.
  • the cross-sectional shape of the linear shaft 30 is not limited to a circle, and may be, for example, a rectangle, a square, an ellipse, or the like, or may have a different shape depending on the portion.
  • the linear shaft 30 may have a visually recognizable depth marker at the base 40 to determine the insertion length into the guiding catheter 100.
  • the rapid exchange type dilator 50 includes a tubular dilator tip tube 60 and a dilator linear shaft 70 connected to the dilator tip tube 60 and extending from the dilator tip tube 60 to the proximal end side. And have. That is, the dilator 50 is also a catheter having an intermediate opening having a tip tube and a linear shaft, similar to the guide extension catheter 10.
  • the dilator 50 can be called an instrument that is inserted into the coronary artery together with the guide extension catheter 10 and smoothly guides to a lesion such as a stenosis that occurs in the coronary artery.
  • the dilator 50 can be called an instrument that is inserted into the coronary artery together with the guide extension catheter 10 and smoothly guides the lesion beyond the lesion such as the stenosis that occurs in the coronary artery, thereby expanding the stenosis.
  • the dilator tip tube 60 is a tubular body having a lumen penetrating from the tip to the base, and has a tip taper portion 61 arranged on the tip side and a tubular portion 62 arranged on the base end side of the tip taper portion 61. And an inclined portion 63 arranged on the base end side of the tubular portion 62.
  • the tip tapered portion 61 is tapered toward the tip side in diameter.
  • the tip tapered portion 61 may have a cylindrical portion whose diameter is tapered toward the tip side and whose outer diameter is constant.
  • the tubular portion 62 is a cylinder having a uniform outer diameter and inner diameter.
  • the outer diameter of the tubular portion 62 is, for example, 0.05 mm smaller than the inner diameter of the tip tube 20.
  • the inner diameter of the tubular portion 62 is larger than the outer diameter of the guide wire to be inserted. As a result, the tubular portion 62 can smoothly move along the guide wire.
  • the inclined portion 63 has a proximal end surface that is inclined with respect to a cross section orthogonal to the axis.
  • the inclined portion 63 may not be provided.
  • the length of the tip tapered portion 61 in the axial direction is not particularly limited, but is, for example, 3 mm to 30 mm.
  • the length of the entire dilator tip tube 60 in the axial direction is not particularly limited, but is, for example, 100 mm to 450 mm.
  • the dilator tip tube 60 preferably has some flexibility and is flexible. Therefore, the constituent materials of the dilator tip tube 60 are, for example, various thermoplastics such as styrene-based, polyolefin-based, polyurethane-based, polyester-based, polyamide-based, polybutadiene-based, transpolyisoprene-based, fluororubber-based, and chlorinated polyethylene-based.
  • the dilator tip tube 60 may contain the above-mentioned X-impermeable material (contrast medium) in the material.
  • the dilator tip tube 60 may contain the above-mentioned X-impermeable material (contrast agent) in the material, or may have a marker made of an X-ray impermeable metal.
  • X-ray opaque metals are, for example, gold, platinum, silver, bismuth, tungsten, or alloys of two or more of these (eg, platinum-tungsten), barium sulfate, or alloys with other metals (eg, gold).
  • -Iridium, platinum-iridium, platinum-nickel and the like.
  • the dilator tip tube 60 is formed, for example, by insert molding the dilator linear shaft 70 in a state of being arranged in the mold.
  • the dilator linear shaft 70 is a flexible wire rod, which is connected to the dilator tip tube 60 and extends from the dilator tip tube 60 to the proximal end side.
  • the dilator linear shaft 70 includes a linear shaft base portion 71 and a shaft tip shape portion 72 arranged and shaped on the tip end side of the shaft base portion 71. Since the shaft base 71 is flexible and bends flexibly, it does not have to be linear at all times.
  • the shaft tip shape portion 72 includes a shaft intermediate straight portion 73 extending from the shaft base 71 to the tip side, a shaft semicircle portion 74 arranged on the tip side of the shaft intermediate straight portion 73, and a shaft from the shaft semicircle portion 74 to the shaft. It is provided with a shaft tip straight portion 75 extending to the side opposite to the side on which the intermediate straight portion 73 is provided.
  • the shaft intermediate straight portion 73 reaches the tubular portion 62 from the proximal end surface of the portion of the inclined portion 63 of the dilator tip tube 60 that protrudes toward the proximal end side. Therefore, the tip of the shaft intermediate straight line portion 73 is located at the tubular portion 62.
  • the shaft intermediate straight line portion 73 is located on the axis of the shaft base portion 71 and is inclined at a minute angle exceeding 0 degrees with respect to the extension line L2 extending from the shaft base portion 71 toward the tip end side. Therefore, the shaft intermediate straight line portion 73 is arranged so as to be offset to one side from the extension line L2.
  • the shaft semicircle portion 74 is bent by changing the direction by about 180 degrees so as to draw a substantially semicircle at the base end portion of the tubular portion 62.
  • the shaft semicircle portion 74 is arranged so as to intersect the extension line L2.
  • the shaft semicircle portion 74 does not have to exactly intersect the extension line L2.
  • the shaft tip straight line portion 75 extends from the end portion of the shaft semicircle portion 74 opposite to the side in contact with the shaft intermediate straight line portion 73 toward the proximal end side.
  • the straight portion 75 at the tip of the shaft is substantially parallel to the extension line L2, but does not have to be strictly parallel.
  • An extension line L2 is arranged between the shaft intermediate straight portion 73 and the shaft tip straight portion 75.
  • the shaft intermediate straight portion 73, the shaft semicircle portion 74, and the shaft tip straight portion 75 are arranged on the same plane.
  • the shaft end portion 76 on the side opposite to the side in contact with the shaft semicircle portion 74 of the shaft tip straight portion 75 is located at the cylindrical portion 62 or the inclined portion 63.
  • the radius of curvature of the shaft semicircular portion 74 does not have to be constant, it may be semi-elliptical, or the direction may exceed 180 degrees, and conversely, it may not be less than 180 degrees.
  • the dilator linear shaft 70 has a dilator straight portion 80 having a constant outer diameter from the proximal end side to the distal end side, and a dilator linear shaft 70 from the distal end of the dilator linear shaft 80. It has a dilator taper portion 81 whose outer diameter is reduced to the tip of the shaft.
  • the dilator straight line portion 80 forms the shaft base portion 71.
  • the dilator taper portion 81 forms the tip portion of the shaft base portion 71, the shaft intermediate straight portion 73, the shaft semicircle portion 74, and the shaft tip straight portion portion 75.
  • the boundary between the dilator straight line portion 80 and the dilator taper portion 81 is arranged on the proximal end side of the dilator tip tube 60, but may be arranged at the proximal end of the dilator tip tube 60 or inside the dilator tip tube 60.
  • the dilator linear shaft 70 is connected to the dilator tip tube 60 after the shaft tip shape portion 72 is shaped into a predetermined shape.
  • the outer diameter of the dilator linear shaft 70 is not particularly limited, but is, for example, 0.05 mm to 1 mm.
  • the length of the base 31 of the dilator linear shaft 70 in the axial direction is not particularly limited, but is, for example, 1000 mm to 1400 mm.
  • the constituent material of the dilator linear shaft 70 is not particularly limited, but for example, stainless steel, nickel-titanium alloy, or the like can be preferably used.
  • the cross-sectional shape of the dilator linear shaft 70 is not limited to a circle, and may be, for example, a rectangle, a square, an ellipse, or the like, or may have a different shape depending on the portion.
  • the dilator linear shaft 70 may have a depth marker that can be visually confirmed in order to grasp the insertion length into the guiding catheter 100.
  • the guide extension catheter 10 and the dilator 50 can be used with the dilator 50 inserted in the guide extension catheter 10 as shown in FIG.
  • the guide extension catheter 10 and the dilator 50 may be packaged in the assembled catheter assembly. As a result, the convenience of the procedure is improved, and the procedure can be performed immediately after opening the package.
  • the dilator tip tube 60 can move in the lumen of the tip tube 20 of the guide extension catheter 10 and partially project from the tip opening 201 of the tip tube 20 toward the tip side. At this time, the tip tapered portion 61 of the dilator tip tube 60 projects toward the tip side from the tip opening 201 of the tip tube 20. After engaging (engaging) the tip of the guiding catheter 100 with the coronary artery ostium, the surgeon causes the guide extension catheter 10 into which the dilator 50 is inserted to protrude from the tip opening 101 of the guiding catheter 100.
  • the dilator tip tube 60 plays a role of smoothly guiding the guide extension catheter 10 to a target position along the guide wire.
  • the target position may be guided to a position in front of the lesion or beyond the lesion.
  • the position of the guide wire is fixed and the dilator tip tube 60 is removed from the guide extension catheter 10.
  • the therapeutic catheter is brought to the lesion along the guide wire through the lumens of the guiding catheter 100 and the guide extension catheter 10.
  • the surgeon can treat the lesion (for example, balloon dilation or stent placement) with a therapeutic catheter.
  • the catheter having an intermediate opening is a catheter having an intermediate opening having an distal tube 20 and a linear shaft 30 extending from the distal tube 20 to the proximal end side, and is a linear shaft.
  • 30 has a shaped tip shape portion 32 and a base portion 31 extending from the tip shape portion 32 to the base end side, and the tip shape portion 32 extends linearly from the base portion 31 to the tip end side.
  • the intermediate straight line portion 33 is inclined with respect to the extension line L1 extending from the base portion 31 to the tip end side, and the semicircular portion 34. Is arranged on the extension line L1, and the tip straight line portion 35 is arranged on the opposite side of the intermediate straight line portion 33 with the extension line L1 interposed therebetween.
  • the tip straight portion 35 and the intermediate straight portion 33 are arranged on both sides of the extension line L1 extending from the base 31, so that the efficiency from the linear shaft 30 to the tip tube 20 is achieved. It can transmit power well. Therefore, when the operator operates the linear shaft 30 located outside the body, the catheter having this intermediate opening can effectively apply a pushing force and a rotational force to the tip tube 20. Further, since the tip straight line portion 35 and the intermediate straight line portion 33 are arranged on both sides of the extension line L1 extending from the base portion 31, the intermediate straight line portion 33, the semicircular portion 34, and the tip straight line portion 35 of the linear shaft 30 are arranged.
  • the linear shaft 30 is prevented from coming off from the tip tube 20 when the base portion 31 is pulled.
  • the catheter having an intermediate opening is a catheter having an intermediate opening having a tip tube 20 and a linear shaft 30 extending from the tip tube 20 to the proximal end side
  • the linear shaft 30 is a catheter having an intermediate opening. It has a shaped tip shape portion 32 and a base portion 31 extending from the tip shape portion 32 to the base end side, and the tip tube 20 is formed by winding or braiding at least one wire rod.
  • the reinforcing body 24 is provided, and the tip shape portion 32 is arranged on the tip side of the intermediate straight line portion 33 extending linearly from the base portion 31 to the tip end side and bends in a substantially half circle.
  • the catheter having the intermediate opening configured as described above, the semicircle portion 34 overlaps with the reinforcing body 24, and the tip straight portion 35 extending from the semicircle portion 34 reaches the proximal end side beyond the reinforcing body 24. Therefore, the range in which the tip straight portion 34 overlaps with the reinforcing body 24 becomes wide, and it is easy to transmit the force from the linear shaft 30 to the reinforcing body 24 for imparting strength to the tip tube 20. Therefore, the catheter having the intermediate opening can efficiently transmit the force from the linear shaft 30 to the tip tube 20. Therefore, when the operator operates the linear shaft 30 located outside the body, the catheter having this intermediate opening can effectively apply a pushing force and a rotational force to the tip tube 20, and during the operation. It is possible to prevent the tip tube 20 and the linear shaft 30 from separating from each other.
  • the linear shaft 30 has at least one tapered portion (first tapered portion 41 and second tapered portion 43) whose outer diameter is tapered toward the tip side.
  • first tapered portion 41 and second tapered portion 43 whose outer diameter is tapered toward the tip side.
  • the linear shaft 30 has a flexible structure in which the rigidity decreases toward the tip side, so that the tip portion is provided with flexibility (flexibility) and the base end portion is provided with high pushability (pushability). Can be granted.
  • the linear shaft 30 has a first straight line portion 40 having a constant outer diameter, a first tapered portion 41 having a reduced outer diameter, and a second straight line having a constant outer diameter from the proximal end side to the distal end side.
  • a portion 42, a second tapered portion 43 having a reduced outer diameter, and a third straight portion 44 having a constant outer diameter are provided, the first straight portion 40 forms a base 31, and the first tapered portion 41 , A portion including the boundary between the base portion 31 and the intermediate straight line portion 33 is formed, and a part of the base end side of the second straight line portion 42, the second tapered portion 43, and the third straight line portion 44 forms the intermediate straight line portion 33.
  • the linear shaft 30 has a flexible structure in which the rigidity is gradually reduced toward the tip end side, so that it is possible to impart flexibility to the tip end portion and to impart high pushability to the base end portion.
  • the tip shape portion 32 may have a smaller outer diameter than the base portion 31 and may be constant. As a result, the tip shape portion 32 has a lower rigidity than the base portion 31 and has a flexible structure, so that it is possible to impart flexibility to the tip portion and to impart high pushability to the base end portion.
  • the catheter having an intermediate opening projects the tip of the therapeutic catheter from the tip opening 101 of the guiding catheter 100, and the coronary artery is along the therapeutic catheter.
  • It may be a guide extension catheter 10 for advancing the inside to the periphery and arranging a treatment portion provided on the treatment catheter to perform treatment on the lesion portion.
  • the guide extension catheter 10 can effectively transmit the pushing force and the rotational force to the tip tube 20, and the tip can be operated during the operation. It is possible to prevent the tube 20 and the linear shaft 30 from separating from each other.
  • the treatment unit provided on the treatment catheter for performing treatment is, for example, a balloon or a stent.
  • the catheter having an intermediate opening projects the tip of the therapeutic catheter from the tip opening 101 of the guiding catheter 100, and the coronary artery is along the therapeutic catheter.
  • It may be a rapid exchange type dilator 50 that advances inside to the periphery and is inserted into a guide extension catheter 10 for arranging a treatment portion provided on the treatment catheter and performing treatment on the lesion portion.
  • the present invention is not limited to the above-described embodiment, and various modifications can be made by those skilled in the art within the technical idea of the present invention.
  • the axis of the tip shape portion 32 may be three-dimensionally arranged beyond the same plane.
  • the terminal portion 36 is arranged away from the plane on which the intermediate straight line portion 33 and the semicircular portion 34 are located.
  • the intermediate straight portion 33, the semicircular portion 34, and the tip straight portion 35 of the linear shaft 30 can be efficiently arranged within the limited wall thickness range of the tip tube 20, so that the wall thickness of the tip tube 20 can be increased. The increase can be suppressed.
  • the linear shaft 30 of the guide extension catheter 10 may be provided with a return portion 37 near the terminal portion 36.
  • the return portion 37 is formed so as to prevent the linear shaft 30 from being pulled out from the distal tube 20 when the linear shaft 30 is pulled toward the proximal end side with respect to the distal tube 20. Therefore, when the return portion 37 is formed on the side where the end portion 36 is arranged rather than the most tip side portion (folded portion) of the semicircle portion 34, the direction away from the outer peripheral surface of the linear shaft 30. And it protrudes toward the tip.
  • the return portion 37 When the return portion 37 is formed on the side where the base portion 31 is arranged rather than the most tip side portion (folded portion) of the semicircular portion 34, the return portion 37 is formed in a direction away from the outer peripheral surface of the linear shaft 30. It protrudes toward the base end. It is preferable that the return portion 37 can be engaged so as to be hooked on the wire rod of the reinforcing body 24. As a result, the return portion 37 can be caught on the reinforcing body 24 of the tip tube 20 and the linear shaft 30 can be strongly suppressed from coming off the tip tube 20.
  • the return portion 37 is formed on the side where the end portion 36 is arranged rather than the most tip side portion (folded portion) of the semicircle portion 34. In the case, it projects in the direction away from the outer peripheral surface of the linear shaft 30 and toward the proximal end.
  • the return portion 37 is formed on the side where the base portion 31 is arranged rather than the most tip side portion (folded portion) of the semicircular portion 34, the return portion 37 is formed in a direction away from the outer peripheral surface of the linear shaft 30. It may be present and protrude toward the tip.
  • the tip tube 20 of the guide extension catheter 10 is arranged on the distal end side of the proximal lumen 20A having a substantially uniform inner diameter and the distal end of the proximal lumen 20A. It may be provided with a tip lumen 20B having an inner diameter that tapers toward the side.
  • the tip tube 20 accommodates a part of the tip tapered portion 61 of the dilator 50 in the tip lumen 20B, and the tubular portion 62 arranged on the proximal end side of the distal tapered portion 61 is formed in the proximal lumen 20A.
  • the tip tube 20 can have a tubular portion 62 having a larger outer diameter than usual in the proximal lumen 20A, the pushability and penetrating force of the dilator tip tube 60 can be improved.
  • the dilator tip tube 60 of the dilator 50 may have a proximal end opening 64 that tapers toward the proximal end side. This makes it possible to improve the insertability of the guide wire into the dilator tip tube 60.
  • the dilator tip tube 60 may have a large diameter portion 65 having a larger outer diameter than the tip portion at the base end portion. By abutting the large diameter portion 65 against the tip tube 20 of the guide extension catheter 10 and causing it to interfere with each other, the dilator 50 can be prevented from protruding too much from the guide extension catheter 10.
  • the dilator tip tube 60 of the dilator 50 may have a plurality of X-ray contrast markers 66 arranged at predetermined intervals (for example, 5 mm intervals) in the axial direction. .. Thereby, the length can be estimated with reference to the X-ray contrast marker 66 under fluoroscopy. This facilitates the surgeon to determine the size of the therapeutic catheter to be inserted later.
  • the color of a part or all of the linear shaft 30 of the guide extension catheter 10 and the linear shaft 70 of the dilator 50 may be different from each other. As a result, it becomes easy to distinguish between the two, and the convenience of the procedure can be improved.
  • a lubricant such as silicon may be applied to the linear shaft 30 or the dilator linear shaft 70 to prevent the shafts from getting entangled with each other.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

L'invention concerne un cathéter auquel une force de pression ou un couple peut être appliqué efficacement, et qui possède une ouverture intermédiaire par laquelle la séparation entre un tube d'extrémité et un arbre linéaire peut être empêchée pendant une chirurgie.　Le cathéter a une ouverture intermédiaire pourvue d'un tube d'extrémité (20) et un arbre linéaire (30), dans laquelle l'arbre linéaire (30) a une partie en forme de pointe (32) et une partie de base (31) qui s'étend à partir de la partie en forme de pointe (32) vers le côté d'extrémité de base, la partie en forme de pointe (32) comprenant une partie linéaire intermédiaire (33) qui s'étend linéairement à partir de la partie de base (31) vers le côté d'extrémité de pointe, une partie semi-circulaire (34) qui est disposée sur le côté d'extrémité de pointe de la partie linéaire intermédiaire (33) et peut être pliée de manière à former approximativement un demi-cercle, et une partie linéaire de pointe (35) qui s'étend linéairement à partir d'une partie d'extrémité située sur le côté opposé d'un côté sur lequel la partie linéaire intermédiaire (33) est disposée vers le côté d'extrémité de base, la partie linéaire intermédiaire (33) est inclinée par rapport à une ligne étendue (L1) qui s'étend à partir de la partie de base (31) vers le côté d'extrémité de pointe, la partie semi-circulaire (34) est disposée sur la ligne étendue (L1), et la partie linéaire de pointe (35) est disposée sur un côté opposé à la partie linéaire intermédiaire (33) à travers la ligne étendue (L1).
PCT/JP2021/043890 2020-12-02 2021-11-30 Cathéter Ceased WO2022118845A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020200283A JP2024012725A (ja) 2020-12-02 2020-12-02 カテーテル
JP2020-200283 2020-12-02

Publications (1)

Publication Number Publication Date
WO2022118845A1 true WO2022118845A1 (fr) 2022-06-09

Family

ID=81853300

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2021/043890 Ceased WO2022118845A1 (fr) 2020-12-02 2021-11-30 Cathéter

Country Status (2)

Country Link
JP (1) JP2024012725A (fr)
WO (1) WO2022118845A1 (fr)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120165756A1 (en) * 2006-05-03 2012-06-28 Vascular Solutions, Inc. Coaxial guide catheter for interventional cardiology procedures
JP2015523186A (ja) * 2012-08-01 2015-08-13 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． ガイドエクステンションカテーテルおよびその製造方法
JP2016517320A (ja) * 2013-03-15 2016-06-16 キューエックスメディカル リミテッド ライアビリティ カンパニー ブースティングカテーテルおよび関連するシステムおよび方法
WO2018030075A1 (fr) * 2016-08-10 2018-02-15 ニプロ株式会社 Cathéter de support.
JP2019511283A (ja) * 2016-04-14 2019-04-25 メドトロニック ヴァスキュラー インコーポレイテッド 螺旋形状の入口ポートを有するガイドエクステンションカテーテル

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20120165756A1 (en) * 2006-05-03 2012-06-28 Vascular Solutions, Inc. Coaxial guide catheter for interventional cardiology procedures
JP2015523186A (ja) * 2012-08-01 2015-08-13 ボストン サイエンティフィック サイムド，インコーポレイテッドＢｏｓｔｏｎ Ｓｃｉｅｎｔｉｆｉｃ Ｓｃｉｍｅｄ，Ｉｎｃ． ガイドエクステンションカテーテルおよびその製造方法
JP2016517320A (ja) * 2013-03-15 2016-06-16 キューエックスメディカル リミテッド ライアビリティ カンパニー ブースティングカテーテルおよび関連するシステムおよび方法
JP2019511283A (ja) * 2016-04-14 2019-04-25 メドトロニック ヴァスキュラー インコーポレイテッド 螺旋形状の入口ポートを有するガイドエクステンションカテーテル
WO2018030075A1 (fr) * 2016-08-10 2018-02-15 ニプロ株式会社 Cathéter de support.

Also Published As

Publication number Publication date
JP2024012725A (ja) 2024-01-31

Similar Documents

Publication Publication Date Title
EP3332830B1 (fr) Cathéter d'extension de guidage
US8449526B2 (en) Torqueable soft tip medical device and method of usage
US8231551B2 (en) Elongate medical device with continuous reinforcement member
EP1712247B1 (fr) Cathéter
EP4039315B1 (fr) Cathéter d'extension de guidage
JP2001218851A (ja) カテーテル
CN106102814B (zh) 导管
AU2002354761A1 (en) Torqueable soft tip medical device and method of usage
JP6765415B2 (ja) ガイドワイヤ
JP4790349B2 (ja) カテーテル
WO2022158418A1 (fr) Cathéter
WO2020255737A1 (fr) Cathéter
WO2022118845A1 (fr) Cathéter
WO2023157440A1 (fr) Dilatateur, ensemble cathéter et procédé d'actionnement d'ensemble cathéter
JP3944395B2 (ja) 脳動脈用カテーテルおよびカテーテル器具
JP2023116319A (ja) カテーテル
WO2022158417A1 (fr) Cathéter
WO2022154118A1 (fr) Cathéter et ensemble cathéter
JP2024040728A (ja) カテーテル
WO2015141392A1 (fr) Cathéter et ensemble cathéter
JPH1176415A (ja) ガイドワイヤ
JP4316252B2 (ja) カテーテル
JP7597196B2 (ja) サポートカテーテルおよびチューブ
JP2025145833A (ja) カテーテルおよびカテーテルの製造方法
JP2025145836A (ja) カテーテル

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 21900598

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 21900598

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: JP