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WO2022142784A1 - Appareil de pose d'anneau de valvuloplastie et système d'annuloplastie - Google Patents

Appareil de pose d'anneau de valvuloplastie et système d'annuloplastie Download PDF

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Publication number
WO2022142784A1
WO2022142784A1 PCT/CN2021/130660 CN2021130660W WO2022142784A1 WO 2022142784 A1 WO2022142784 A1 WO 2022142784A1 CN 2021130660 W CN2021130660 W CN 2021130660W WO 2022142784 A1 WO2022142784 A1 WO 2022142784A1
Authority
WO
WIPO (PCT)
Prior art keywords
annuloplasty ring
accommodating
delivery device
cavity
annuloplasty
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2021/130660
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English (en)
Chinese (zh)
Inventor
郭荣辉
张庭超
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hangzhou Valgen Medtech Co Ltd
Original Assignee
Hangzhou Valgen Medtech Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CN202023242587.7U external-priority patent/CN215384905U/zh
Priority claimed from CN202011593343.5A external-priority patent/CN114681128B/zh
Application filed by Hangzhou Valgen Medtech Co Ltd filed Critical Hangzhou Valgen Medtech Co Ltd
Publication of WO2022142784A1 publication Critical patent/WO2022142784A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body

Definitions

  • the present disclosure relates generally to the field of medical device technology, and more particularly to annuloplasty ring delivery devices and annuloplasty systems.
  • Mitral valve insufficiency is one of the most common heart valve diseases today.
  • the main causes are rheumatic heart disease, mitral valve myxoid degeneration, cardiac ischemic disease, cardiomyopathy, etc.
  • the leaflets, chordae tendineae, and papillary muscles develop lesions that prevent the leaflets of the mitral valve from closing completely.
  • Mitral valve annulus reduction also known as mitral valve annuloplasty, is one of the basic procedures for mitral valve surgical repair. Reduce mitral regurgitation while maintaining the physiological integrity of the mitral valve structure. For example, an artificial valve annulus is implanted on the valve annulus, and then discontinuous U-shaped sutures are made along the attachment portion of the valve leaflets with non-invasive sutures, and then the size of the valve annulus is adjusted by tightening the sutures to achieve the effect of shrinking the ring.
  • the prior art discloses an apparatus for the treatment of mitral regurgitation using interventional mitral annuloplasty, which utilizes the interventional instrument to apply a plurality of sutures to the annulus of the mitral valve, and then couple the plurality of sutures to the annulus of the mitral valve. On the annuloplasty ring, the annuloplasty ring is then slid down the suture through the channel to reach the mitral valve.
  • annuloplasty ring delivery device comprising:
  • the accommodating piece is provided with an accommodating cavity in the axial direction, and the two opposite sides of the accommodating piece are provided with a through groove in the axial direction, the through groove communicates with the accommodating cavity, and the accommodating part a cavity for receiving the annuloplasty ring;
  • a lead assembly the lead assembly includes a branch piece and at least one conduit communicating with both ends, the branch piece includes a main cavity passing through in the axial direction and a plurality of branch holes communicating with the main cavity in a radial direction, the The accommodating part is detachably accommodated in the main cavity, and each of the conduits movably passes through the branching hole.
  • the wire splitter includes a first cover body and a second cover body that are detachably coupled.
  • the distal end of the accommodating member is provided with an opening, and the opening communicates with the accommodating cavity and the through groove.
  • the annuloplasty ring delivery device further includes a pusher, the distal end of the pusher being movably received in the receiving cavity.
  • the pushing member comprises a pushing rod and a pushing block fixedly connected with the distal end of the pushing rod, wherein the cross-sectional area of the pushing block in the radial direction is larger than the cross-sectional area of the pushing rod in the radial direction.
  • the annuloplasty ring delivery device further comprises a sheath tube, the sheath tube is fixedly connected with the proximal end of the accommodating member, the inner lumen of the sheath tube communicates with the accommodating cavity, and the The pushing member is movably accommodated in the inner cavity of the sheath tube and the accommodating cavity.
  • the annuloplasty ring delivery device further comprises a manipulation assembly comprising a handle and an operating member disposed on the handle, the handle being fixedly connected to the proximal end of the sheath, The operating member is connected to the proximal end of the pushing member and used to control the axial movement of the pushing member.
  • the lead assembly further includes a lead member movably extending through the catheter, the lead member including a rod-shaped portion and an annular portion provided at one end of the rod-shaped portion.
  • the present disclosure provides an annuloplasty system comprising an annuloplasty ring and the above-described annuloplasty ring delivery device, the annuloplasty ring being accommodated in a accommodating cavity of the accommodating member.
  • the annuloplasty ring is made of a shape memory material, and the annuloplasty ring is C-shaped in its natural state.
  • Certain embodiments of the present disclosure provide an annuloplasty ring delivery device and an annuloplasty system in which the annuloplasty ring is housed in a housing lumen of a housing that is in turn housed in a main portion of a wire divider of a lead assembly. Then, the catheter is passed through the shunt hole of the shunt, and the catheter is passed through the annuloplasty ring in the accommodating cavity through the through slot.
  • the sutures can be threaded on the annuloplasty ring, so as to couple a plurality of sutures on the original valve annulus to the annuloplasty ring, and the operation is simple, convenient and quick.
  • FIG. 1 is a schematic structural diagram of an annuloplasty ring delivery device provided by an embodiment of the present disclosure
  • FIG. 2 is another schematic structural diagram of the annuloplasty ring delivery device provided by an embodiment of the present disclosure
  • FIG. 3 is a schematic structural diagram of a accommodating member and a sheath tube provided by an embodiment of the present disclosure
  • 4 to 7 are schematic structural diagrams of a lead assembly provided by an embodiment of the present disclosure.
  • FIG. 8 is a schematic structural diagram of an annuloplasty ring in a natural state provided by an embodiment of the present disclosure
  • FIG. 9 is a schematic structural diagram of a valvuloplasty ring provided in an embodiment of the present disclosure when it is placed in a accommodating member;
  • 10 to 13 are schematic structural diagrams of a accommodating member provided by an embodiment of the present disclosure.
  • FIG. 14 is a schematic structural diagram of an annuloplasty ring delivery device provided by an embodiment of the present disclosure.
  • FIG. 15 is a cross-sectional view of a accommodating member and a pushing member provided by an embodiment of the present disclosure
  • 16 to 19 are schematic views of the operation of the annuloplasty ring delivery device provided by an embodiment of the present disclosure.
  • FIG. 20 is a schematic diagram of a native mitral valve annulus provided by an embodiment of the present disclosure.
  • FIG. 21 is a schematic diagram of locking an interventional locking device according to an embodiment of the present disclosure.
  • the proximal end refers to the end closer to the operator, while the distal end refers to the end farther away from the operator;
  • the axial direction refers to the end parallel to the medical device. The direction of the line connecting the center of the distal end and the center of the proximal end of the instrument.
  • an annuloplasty system includes an annuloplasty ring 3 and an annuloplasty ring delivery device 1 .
  • the annuloplasty ring delivery device 1 is used to couple a plurality of sutures 2 that have been sewn into the native annulus 4 of the heart to the annuloplasty ring 3, and to attach the annuloplasty ring along the plurality of sutures 2 through a minimally invasive interventional path. 3 is delivered to the atrium.
  • the annuloplasty ring delivery device 1 can be used to deliver the annuloplasty ring 3 in mitral annuloplasty and tricuspid annuloplasty, with minimally invasive intervention, and the annuloplasty ring can be implanted without cardiac arrest 3 .
  • the annuloplasty ring delivery device 1 includes a receiver 10 , a lead assembly 20 , a pusher 30 , a steering assembly 40 and a sheath 50 .
  • the accommodating member 10 is provided with a accommodating cavity 11 in the axial direction, and the two opposite sides of the accommodating member 10 are provided with through grooves 12 in the axial direction.
  • the through grooves 12 communicate with the accommodating cavity 11 and the accommodating cavity 11 is used to accommodate the annuloplasty ring 3 .
  • the lead wire assembly 20 includes a branching member 21 and at least one conduit 22 communicating with both ends.
  • the wire splitting member 21 includes a main cavity 214 passing through in the axial direction and a plurality of wire branching holes 213 communicating with the main cavity 214 in the radial direction.
  • the accommodating member 10 is detachably accommodated in the main cavity 214 , and the conduit 22 movably passes through the branching hole 213 .
  • the annuloplasty ring 3 is accommodated in the accommodating cavity 11 of the accommodating member 10, and the accommodating member 10 is then accommodated in the main cavity 214 of the branching member 21 of the lead assembly 20, and then The catheter 22 is inserted into the shunt hole 213 of the shunt piece 21, and the catheter 22 passes through the annuloplasty ring 3 in the accommodating cavity 11 through the through slot 12 at the same time. 2. Passing through the catheter 22, after withdrawing the catheter 22, the sutures 2 can be threaded on the annuloplasty ring 3, thereby coupling the plurality of sutures 2 on the original annulus 4 to the annuloplasty ring 3, which is easy and convenient to operate fast.
  • lead assembly 20 may include one conduit 22 or multiple conduits 22 .
  • the catheter 22 can be movably passed through the shunt hole 213 of the shunt 21. Since the accommodating member 10 with the annuloplasty ring 3 built in is accommodated in the main cavity 214 of the shunt 21, the catheter 22 can pass through the shunt hole 213. One end of the accommodating member 10 is penetrated, and then penetrates into the accommodating cavity 11 from the through groove 12 on one side of the accommodating member 10, and passes through the annuloplasty ring 3 located in the accommodating cavity 11, and then passes through the valvuloplasty ring 3 on the other side of the accommodating member 10. Pass through the through slot 12 , and finally pass out from the other end of the wire splitting hole 213 .
  • the catheter 22 passes through the shunt hole 213 and passes through the annuloplasty ring 3 in the accommodating cavity 11 through the through slot 12 . Therefore, the operator passes the suture 2 that has been sewn into the native valve annulus 4 through the catheter 22 , and then withdraws the catheter 22 to keep the suture 2 threaded on the annuloplasty ring 3 in the accommodating cavity 11 .
  • Using a detachable catheter 22 to guide the suture 2 into the annuloplasty ring 3 is easy to operate, and can also shorten the operation time and improve the operation efficiency.
  • the suture 2 is passed through the shunt hole 213 on the annuloplasty ring 3, and the position of the suture 2 on the annuloplasty ring 3 is determined by the shunt hole 213.
  • the relative position to the annuloplasty ring 3 is determined. Due to the fixed positions of the plurality of shunt holes 213 on the shunt piece 21 , it can ensure that the suture 2 is passed through the proper position on the annuloplasty ring 3 and the distance between the adjacent sutures 2 is uniform, thereby ensuring that the annuloplasty ring 3 Uniform shrinkage after being stressed.
  • the annuloplasty ring 3 is made of a shape memory material, and the annuloplasty ring 3 is in a C-shape in a natural state, that is, the annuloplasty ring 3 has a natural state and a delivery state, and its two ends in the natural state. Open and C-shaped; when accommodated in a conveying device, it is in a straight-shaped conveying state.
  • the annuloplasty ring 3 has superelasticity, and in some embodiments, an implantable material with suitable elastic properties, such as silica gel and nickel-titanium alloy, can be used. As shown in FIG. 13 , the annuloplasty ring 3 can be accommodated in the accommodating member 10 in a flat state due to its superelasticity.
  • annuloplasty ring 3 in the annuloplasty ring delivery device 1 in a straight state can minimize the external dimension of the annuloplasty ring delivery device 1, which is beneficial to reduce the wound, and thus can reduce the operation caused by the excessive wound. resulting risks.
  • the annuloplasty ring 3 can also be provided in other shapes and accommodated in the annuloplasty ring delivery device 1, such as a helical shape. As shown in FIG. 12 , when the annuloplasty ring delivery device 1 reaches the atrium, the annuloplasty ring 3 can be pushed out from the accommodating member 10 to restore the annuloplasty ring 3 to its natural state, which is C-shaped.
  • the shape and size of the annuloplasty ring 3 in the natural state is the same as or close to the shape and size of the original valve annulus 4.
  • the lead assembly 20 includes a branching member 21 , a conduit 22 and a lead member 23 .
  • the wire splitting member 21 includes a first cover body 211 and a second cover body 212 that are detachably matched. After the first cover body 211 and the second cover body 212 are closed together, a main cavity 214 which penetrates in the axial direction and a plurality of branch holes 213 which communicate with the main cavity 214 in the radial direction are formed. In this way, the first cover body 211 and the second cover body 212 , which are detachably matched, are convenient for the accommodating member 10 to be accommodated in the main cavity 214 of the wire splitting member 21 .
  • the wire splitting member 21 further includes a locking knob 215 , and locking holes 216 are respectively provided at positions corresponding to the first cover body 211 and the second cover body 212 .
  • the locking knob 215 can pass through the locking holes 216 on the first cover body 211 and the second cover body 212 in sequence, and the first cover body 211 and the The second cover body 212 is locked so as to fix the accommodating member 10 in the main cavity 214 of the wire splitting member 21 .
  • the first cover body 211 and the second cover body 212 are respectively provided with two locking holes 216 correspondingly.
  • the first cover body 211 and the second cover body 212 can fix the accommodating member 10 in the main cavity 214 of the wire splitting member 21 by means of snap-fit.
  • the number of the branching holes 213 is multiple, and they are arranged at intervals along the axial direction of the branching member 21 .
  • the number of shunting holes 213 is 16, which are evenly spaced along the axial direction of the shunt piece 21, so that the 16 sutures that have been sewn into the native valve annulus 4 can be respectively sutured through the 16 shunting holes
  • the threads 2 are coupled to the annuloplasty ring 3 evenly spaced apart to ensure that the sutures 2 are passed in the proper position on the annuloplasty ring 3 .
  • the lead assembly 20 can be configured with stubs 21 with different numbers of shunting holes 213 , and the splinter 21 with the same number of shunting holes 213 can be selected according to the number of sutures 2 sewn into the native valve annulus 4 .
  • the annuloplasty ring 3 When the annuloplasty ring 3 is made of a soft shape memory material such as silica gel, the annuloplasty ring 3 may not be provided with a threading hole.
  • the annuloplasty ring 3 is first accommodated in the accommodating cavity 11, then the first cover 211 and the second cover 212 are used to cover and fix the accommodating member 10, and then the catheter 22 is passed through the dividing chamber In the wire hole 213 , the catheter 22 can penetrate through the annuloplasty ring 3 while passing through the branching hole 213 , and a threading hole is formed on the annuloplasty ring 3 .
  • the suture 2 is passed through the catheter 22, and then the catheter 22 is withdrawn along the free end of the suture 2, so that the suture 2 can be coupled to the annuloplasty ring 3.
  • the annuloplasty ring 3 When the annuloplasty ring 3 is made of a shape memory material such as nickel-titanium alloy, the annuloplasty ring 3 can be provided with a plurality of threading holes corresponding to the plurality of branch holes 213 , and the accommodating member 10 is accommodated in the main cavity 214 of the wire branching member 21 . In the middle, the threading hole of the annuloplasty ring 3 is connected with the threading hole 213 one by one.
  • the annuloplasty ring 3 is first accommodated in the accommodating cavity 11, and then a plurality of catheters 22 are respectively passed through the multiple threading holes of the annuloplasty ring 3, and then pass through the first cover 211 and The second cover 212 covers the fixed accommodating member 10 and the plurality of conduits 22 .
  • the suture 2 is passed through the catheter 22, and then the catheter 22 is withdrawn along the free end of the suture 2, so that the suture 2 can be coupled to the annuloplasty ring 3.
  • the wire splitting member 21 can be made of polymer material or metal material. In order to facilitate the observation of the internal situation of the splitter 21, it is a transparent polymer material in some embodiments, such as polymethyl methacrylate (polymethyl methacrylate, PMMA for short), polycarbonate (poly-carbonate, PC for short). ) and other polymer materials.
  • the catheter 22 can be made of a polymer material with certain support, such as poly-ether-ether-ketone (PEEK for short), polyimide (PI for short) and other polymer materials.
  • the lead assembly 20 further includes a lead member 23 , and the lead member 23 is movable through the catheter 22 .
  • the lead member 23 includes a rod-shaped portion 231 and an annular portion 232 provided at one end of the rod-shaped portion 231 .
  • the suture 2 can pass through the annular portion 232 , and the rod-shaped portion 231 is used to drive the suture 2 through the catheter 22 .
  • the lead member 23 can be moved in the through catheter 22, and then the suture 2 can be passed through the annular portion 232 of the lead member 23 and pulled At the other end of the rod-shaped portion 231, the suture 2 is guided through the catheter 22, and then the catheter 22 is withdrawn along the free end of the suture 2, so that the suture 2 can be threaded on the annuloplasty ring 3, at this time Complete the lead of suture 2.
  • the annular portion 232 may be a metal ring, specifically, may be made of elastic metal wire, which in some embodiments is a Nitinol wire with superelastic properties.
  • the rod-shaped portion 231 may be a straight rod, and may be specifically made of 304 stainless steel or Nitinol.
  • the accommodating member 10 includes a accommodating cavity 11 and a through groove 12 , the distal end of the accommodating member 10 is provided with an opening, and the opening connects the accommodating cavity 11 and the through groove 12 .
  • the accommodating member 10 is a cylindrical structure with an opening 10 a at the distal end and a connecting cavity at the proximal end for connecting the sheath tube 50 .
  • the accommodating member 10 can also be a columnar structure with other shapes.
  • the accommodating member 10 can be made of a metal material or a polymer material with strong rigidity, such as 304 stainless steel, polyether ether ketone and the like.
  • the annuloplasty ring delivery device 1 further includes a pusher 30 , and the distal end of the pusher 30 is movably accommodated in the accommodating cavity 11 . In this way, after the plurality of sutures 2 are coupled to the annuloplasty ring 3 , the annuloplasty ring 3 can be pushed out of the accommodating cavity 11 through the pusher 30 .
  • the pushing member 30 includes a pushing rod 31 and a pushing block 32 fixedly connected with the distal end of the pushing rod 31 .
  • the push rod 31 is fixedly connected with the push block 32, and the fixed connection method includes connection methods such as welding, bonding or snapping.
  • the push block 32 is movably accommodated in the accommodating cavity 11 , and the cross-sectional area of the push block 32 in the radial direction is larger than the cross-sectional area of the push rod 31 in the radial direction. In this way, the contact area between the pushing block 32 and the annuloplasty ring 3 can be increased, thereby improving the stability of pushing the annuloplasty ring 3 out of the accommodating cavity 11 .
  • the pushing block 32 and the pushing rod 31 can be integrally formed, so that the annuloplasty ring 3 can be pushed out of the accommodating cavity 11 more stably.
  • the push rod 31 and the push block 32 can be made of metal material or polymer material with strong rigidity, such as 304 stainless steel, or polyether ether ketone.
  • the annuloplasty ring delivery device 1 further includes a sheath 50, which is a tubular structure with an inner lumen.
  • the sheath 50 is used to receive the pusher 30 .
  • the sheath tube 50 is fixedly connected to the proximal end of the accommodating member 10.
  • the sheath tube 50 is fixedly connected to the connection cavity of the proximal end of the accommodating member 10, and the fixed connection method is welding, bonding or snapping, etc. Way.
  • the inner cavity of the sheath tube 50 communicates with the accommodating cavity 11 , and the pushing member 30 is movably accommodated in the inner cavity of the sheath tube 50 and the accommodating cavity 11 .
  • the sheath tube 50 can be made of a rigid metal material or a polymer material, such as 304 stainless steel or polyether ether ketone.
  • the annuloplasty ring delivery device 1 further includes a manipulation assembly 40 , and the manipulation assembly 40 includes a handle 42 and an operating member 41 disposed on the handle 42 .
  • the handle 42 is fixedly connected to the proximal end of the sheath tube 50
  • the operating member 41 is connected to the proximal end of the pushing member 30 and is used to control the axial movement of the pushing member 30 .
  • the pushing member 30 can be driven to move axially by manipulating the operating member 41 , so that the annuloplasty ring 3 can be pushed out of the accommodating member 10 .
  • the operating member 41 includes a knob and a slider, the slider is located in the inner cavity of the handle 42 , and the knob is coaxially arranged with the handle 42 .
  • the sliding block is fixedly connected with the proximal end of the pushing member 30 , that is, the sliding block is fixedly connected with the proximal end of the pushing rod 31 .
  • the peripheral side of the slider is provided with external threads, and the knob is provided with internal threads matched with the external threads. The slider is driven to move in the axial direction by rotating the knob, so that the pushing member 30 is controlled to move in the axial direction through the rotation of the knob.
  • the operating member 41 may also only include a knob, which is directly threadedly connected to the push rod 31 through the knob, and is rotated to drive the push rod 31 to move in the axial direction.
  • the entire control assembly 40 may be made of high-strength polymer materials, such as Acrylonitrile Butadiene Styrene plastic (ABS for short), Polypropylene (PP for short).
  • the operation process of the annuloplasty ring delivery device 1 provided by the embodiment of the present disclosure is as follows.
  • the annuloplasty ring 3 is placed in the accommodating cavity 11 of the accommodating member 10 , and the accommodating member is placed in the main cavity 214 of the wire dividing member 21 for fixation, and the catheter 22 is inserted through the wire dividing hole 213 of the wire dividing member 21 on the annuloplasty ring 3.
  • the free end of the suture 2 that has been sutured to the native annulus 4 is passed through the annular portion 232 of the lead piece 23 , and the free end of the suture line 2 is passed through the catheter 22 through the lead piece 23 .
  • the threading of each suture thread 2 can be completed in sequence according to the serial number marked on the lead assembly 20 .
  • the position of the first branching hole 213 at the distal end of the lead assembly 20 corresponds to the position of the right fiber triangle in the native valve annulus 4 .
  • the order of the suture 2 on the annuloplasty ring 3 is right fibrous triangle, P3, P2, P1, and left fibrous triangle.
  • AV represents the aortic valve aortic valve
  • CS represents the coronary sinus of the coronary sinus
  • ALC represents the left fibrous triangle
  • PMC represents the right fibrous triangle
  • A1/A2/A3, and P1/P2/P3 represent the upper valvuloplasty ring 3, respectively.
  • the native valve annulus 4 in the embodiment of the present disclosure is the native valve annulus of the mitral valve.
  • the catheter 22 is withdrawn, the accommodating member 10 and the wire dividing member 21 are separated, and the wire dividing member 21 is withdrawn. Specifically, unlock the first cover 211 and the second cover 212 of the wire splitter, separate and remove the first cover 211 and the second cover 212 .
  • each suture 2 is passed through the annuloplasty ring 3 in the annuloplasty ring delivery device 1, and the other end of the suture 2 is sutured to the patient's native annulus. 4 on.
  • the distal end of the annuloplasty ring delivery device 1 passes through the minimal incision of the heart and enters a target location in the heart such as the left atrium.
  • the annuloplasty ring delivery device 1 After the annuloplasty ring delivery device 1 enters the target position, the annuloplasty ring 3 is pushed out by driving the operating member 41. At this time, the annuloplasty ring 3 and the suture 2 will be pushed out from the annuloplasty ring delivery device 1 at the same time.
  • the annuloplasty ring 3 is completely pushed out of the accommodating cavity 11 of the annuloplasty ring delivery device 1 and released, and the annuloplasty ring 3 is restored to its natural state due to its shape memory function, and is aligned with the shape structure of the native valve annulus 4, that is, the valve.
  • the annulus 3 is aligned with the positions P1, P2, and P3 of the native annulus 4.
  • the annuloplasty ring 3 is attached to the native valve annulus 4 and the adjacent sutures 2 are locked in turn or multiple sutures 2 are locked together, thereby completing the valve.
  • the implantation of the forming ring 3 achieves the ring shrinking effect. Since the interventional locking device 5 is relatively common in the field of interventional medicine, it will not be described in detail here.

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  • Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne un appareil de pose (1) d'anneau de valvuloplastie (3) et un système d'annuloplastie ; l'appareil de pose (1) d'anneau de valvuloplastie (3) comprend un élément de réception (10) et un ensemble fil de guidage (20) ; l'élément de réception (10) est pourvu d'une cavité de réception (11) disposée le long de la direction axiale et utilisée pour recevoir l'anneau de valvuloplastie (3) ; les côtés opposés de l'élément de réception (10) sont pourvus d'une rainure traversante (12) le long de la direction axiale en communication avec la cavité de réception (11) ; l'ensemble fil de guidage (20) comprend un élément de séparation de fils (21) et au moins un cathéter (22) en communication aux deux extrémités ; l'élément de séparation de fils (21) comprend une cavité principale (214) s'étendant axialement à travers celui-ci et une pluralité de séparation de fils (213) qui sont radialement en communication avec la cavité principale (214) ; l'élément de réception (10) est logé de manière amovible dans la cavité principale (214) ; chaque cathéter (22) s'étend de façon mobile à travers les trous de séparation de fils (213). Dans l'appareil de pose (1) d'anneau de valvuloplastie (3) décrit, les cathéters (22) passent à travers les trous de séparation de fils (213) de l'élément de séparation de fils (21) et passent également à travers l'anneau de valvuloplastie (3) dans la cavité de réception (11) au moyen de la rainure traversante (12), exécutant une suture (2), déjà cousu dans l'anneau natif, à travers les cathéters (22), et, lors du retrait des cathéters (22), peut coupler une pluralité de sutures (2), sur l'anneau natif, sur l'anneau de valvuloplastie (3).
PCT/CN2021/130660 2020-12-29 2021-11-15 Appareil de pose d'anneau de valvuloplastie et système d'annuloplastie Ceased WO2022142784A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CN202023242587.7 2020-12-29
CN202023242587.7U CN215384905U (zh) 2020-12-29 2020-12-29 瓣膜成形环输送装置和瓣环成形术系统
CN202011593343.5 2020-12-29
CN202011593343.5A CN114681128B (zh) 2020-12-29 2020-12-29 瓣膜成形环输送装置和瓣环成形术系统

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WO2022142784A1 true WO2022142784A1 (fr) 2022-07-07

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PCT/CN2021/130660 Ceased WO2022142784A1 (fr) 2020-12-29 2021-11-15 Appareil de pose d'anneau de valvuloplastie et système d'annuloplastie

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Citations (9)

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US20070078514A1 (en) * 2005-09-30 2007-04-05 Ryan Timothy R Method of implanting an annuloplasty prosthesis
US20070083259A1 (en) * 2005-10-11 2007-04-12 Medtronic Vascular, Inc. Annuloplasty device having shape-adjusting tension filaments
US20080262609A1 (en) * 2006-12-05 2008-10-23 Valtech Cardio, Ltd. Segmented ring placement
US20120022644A1 (en) * 2008-12-22 2012-01-26 Valtech Cardio, Ltd. Partially-adjustable annuloplasty structure
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