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WO2022027963A1 - Procédé de construction d'endoprothèse vasculaire fondé sur la modularisation - Google Patents

Procédé de construction d'endoprothèse vasculaire fondé sur la modularisation Download PDF

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Publication number
WO2022027963A1
WO2022027963A1 PCT/CN2021/080252 CN2021080252W WO2022027963A1 WO 2022027963 A1 WO2022027963 A1 WO 2022027963A1 CN 2021080252 W CN2021080252 W CN 2021080252W WO 2022027963 A1 WO2022027963 A1 WO 2022027963A1
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WO
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Prior art keywords
stent
stents
vascular
type
cutting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/CN2021/080252
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English (en)
Chinese (zh)
Inventor
葛思茗
王盛强
周艺
李斯
栾靖旸
王佳珺
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shanghai Endovas Medical Technologies Co Ltd
Original Assignee
Shanghai Endovas Medical Technologies Co Ltd
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Filing date
Publication date
Application filed by Shanghai Endovas Medical Technologies Co Ltd filed Critical Shanghai Endovas Medical Technologies Co Ltd
Priority to GB2301841.9A priority Critical patent/GB2612731B/en
Publication of WO2022027963A1 publication Critical patent/WO2022027963A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06—Blood vessels
    • A61F2/07—Stent-grafts
    • G—PHYSICS
    • G06—COMPUTING OR CALCULATING; COUNTING
    • G06F—ELECTRIC DIGITAL DATA PROCESSING
    • G06F30/00—Computer-aided design [CAD]
    • G06F30/20—Design optimisation, verification or simulation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/101—Computer-aided simulation of surgical operations
    • A61B2034/102—Modelling of surgical devices, implants or prosthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/10—Computer-aided planning, simulation or modelling of surgical operations
    • A61B2034/108—Computer aided selection or customisation of medical implants or cutting guides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B34/00—Computer-aided surgery; Manipulators or robots specially adapted for use in surgery
    • A61B34/25—User interfaces for surgical systems
    • A61B2034/256—User interfaces for surgical systems having a database of accessory information, e.g. including context sensitive help or scientific articles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/24—Heart valves ; Vascular valves, e.g. venous valves; Heart implants, e.g. passive devices for improving the function of the native valve or the heart muscle; Transmyocardial revascularisation [TMR] devices; Valves implantable in the body
    • A61F2/2442—Annuloplasty rings or inserts for correcting the valve shape; Implants for improving the function of a native heart valve
    • A61F2/2445—Annuloplasty rings in direct contact with the valve annulus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2240/00—Manufacturing or designing of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2240/001—Designing or manufacturing processes
    • A61F2240/002—Designing or making customized prostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/006—Additional features; Implant or prostheses properties not otherwise provided for modular
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body

Definitions

  • the invention relates to a method for constructing a blood vessel stent, in particular to a method for constructing a blood vessel stent based on modularization.
  • vascular stenosis can be mainly divided into the following two categories: 1. Congenital vascular abnormalities cause vascular stenosis. For such patients, if no symptoms are caused, close observation is required. If clinical symptoms are caused, further vascular CTA or DSA imaging is required to determine whether or not to open or not. Second, vascular stenosis is caused by acquired diseases. The most common diseases that cause vascular stenosis are arteriosclerosis and occlusion. The reasons for arteriosclerosis are mostly high blood pressure, hyperglycemia and hyperlipidemia. There are many external factors, the most important of which is smoking, because smoking can cause vasospasm, which can lead to the formation of arteriosclerosis and even occlusion in the long run.
  • the elasticity of the blood vessels of the human body will gradually weaken as the age increases, the vascular endothelium will be damaged, and the cholesterol in the blood will be deposited in the endothelium through the injury to form porridge. sclerotic plaques. The vascular endothelium will become rough and bulge, and the inner diameter of the blood vessel will become narrow.
  • the relevant medical methods include traditional open surgery.
  • unstable factors such as large trauma and poor efficacy have led to the lack of clinical use of this treatment method, and the target blood vessels are prone to thrombosis after open surgery.
  • Endovascular surgery is currently the ideal main method for the treatment of vascular stenosis.
  • a vascular stent is placed at the stenosis of the blood vessel. If necessary, balloon expansion can be performed before implantation. The trauma is small and the success rate is high.
  • the clinical effect is better than that of open surgery, there are still some defects caused by the performance of the stent itself.
  • the metal vascular stents suitable for clinical use mainly have the following two structures: cutting metal stents , engraved by laser; metal braided stent, braided from filamentary metal.
  • the former can be accurately positioned and placed in the diseased blood vessel and has excellent supporting performance.
  • the use of long-segment cutting stents is prone to thrombosis in the stent, and the cutting-type stents have poor flexibility and cannot be used for long-segment stents. It spans the entire diseased blood vessel; the metal braided stent has good flexibility and ideally fits the diseased blood vessel.
  • Vascular stents are clinically used for interventional medical devices to treat vascular stenosis.
  • the choice of stents by professional medical staff depends on the specific vascular conditions of patients. For long-segment vascular lesions, it is difficult for a single stent to correspond appropriately and be suitable for treatment.
  • multiple stents are spliced or hybrid stents with different structures and properties are used for combined treatment.
  • the stent splicing method is to use laser welding to weld the overlapping sections of the two stents.
  • a relatively suitable model is selected for treatment, but there will still be some inappropriateness or insufficient matching with blood vessels, and the selection process also prolongs the total time required for the treatment process. Therefore, it is very necessary to provide a method for constructing a vascular stent based on modularization, and it is necessary to modularly select an appropriate stent to construct a vascular stent according to the state of the diseased blood vessel.
  • the technical problem to be solved by the present invention is to provide a method for constructing a vascular stent based on modularization, which modularizes the combination process of the stent required for treatment, improves the degree of freedom of vascular stent selection and the treatment efficiency; Corresponding stents are required for outgoing blood vessels.
  • the stents are directly selected from the database and connected.
  • the stents are connected regularly without overlapping, and the connection strength is high.
  • the technical solution adopted by the present invention to solve the above-mentioned technical problem is to provide a method for constructing a vascular stent based on modularization, which includes the following steps: S1: Counting vascular stent data, using the vascular stent as a module, and establishing a stent module database; S2: obtaining Diseased blood vessel data, partition the diseased blood vessel; S3: Select the stent module matching each subregion from the stent module database according to the size of each subregion of the diseased blood vessel and the lesion status; S4: Adjust the stent module model according to the connection status of each subregion, Confirm the connection position and splicing method between the stent modules in each sub-area; S5: Assemble the stent modules in each sub-area according to the connection position and splicing mode between the stent modules in each sub-area to complete the construction of the vascular stent.
  • establishing a stent module database in the step S1 includes inputting the data of the vascular stent into the database according to the material, structure, function, application scenario and specification classification of the vascular stent; the vascular stent is classified by material including metal stents and biological material stents, Metal stents include cutting metal stents and braided metal stents; vascular stents are classified according to surface treatment conditions, including bare type, coated type and covered type; vascular stents are classified according to their functions, including simple support stents and therapeutic stents, and therapeutic stents It includes stents and radioactive stents that are coated with drugs on the surface of the stent or use the coating outside the stent to carry therapeutic substances.
  • the diseased blood vessel is divided into a meandering area and a scar area, and the meandering area and the scar area are at least one.
  • the step S3 specifically includes: selecting a braided metal stent for the meandering area, and selecting a cutting-type stent for the scar area, where the cutting-type stent includes a cutting-type metal stent and a cutting-type biomaterial stent; and selecting the scar area corresponding to the lesion.
  • Therapeutic stents with drugs; therapeutic stents loaded with antibodies are selected for serpentine areas with mild stenosis.
  • the cutting type bracket and the braided metal bracket are spliced by a collar-type non-overlapping connection structure, which specifically includes: when the cutting type bracket is laser engraved and formed, a connection ring with holes is arranged at the connection point; the braided metal bracket is When the stent is braided, a break is set at the connection point, and a twist angle is set at the end of the break point to match the connection ring for connection; the connecting ring of the cutting stent is inserted into the break point of the braided metal stent, and the connection is made by laser welding. The tube seals the fracture of the braided stent, and then moves the connecting ring of the cut stent to the twist angle to complete the connection.
  • a collar-type non-overlapping connection structure which specifically includes: when the cutting type bracket is laser engraved and formed, a connection ring with holes is arranged at the connection point; the braided metal bracket is When the stent is braided, a break is set at the connection point, and
  • connection points of the collar type non-overlapping connection structure is 3-24.
  • the therapeutic stent with drugs selected for the lesioned scar area is a therapeutic stent loaded with paclitaxel or rapamycin.
  • the present invention has the following beneficial effects: the modularization-based vascular stent construction method provided by the present invention enables modular combination of stents, flexible deployment of stents for combination with high degree of freedom and high degree of matching, thereby improving treatment efficiency; Drug stents can also be used in the specific conditions of blood vessels, and the treatment effect is good; the modular combination of stents can improve the radial support force and the expansion performance of the stents in the blood vessels under the condition of flexibility and effective preservation; the use of collar type The connection structure is connected without overlapping.
  • the structural strength of the regular filamentary material after welding with the connecting pipe is higher than that of the irregular structure directly welded or brazed, and the outer surface of the stent does not produce any burrs; no overlapping sections Waste, stable structure, smoother release process, less friction in the sheath, less risk of breakage, and relatively long product life.
  • FIG. 1 is a flowchart of a method for constructing a vascular stent based on modularization in an embodiment of the present invention
  • FIG. 2 is a schematic diagram of a blood vessel partition in an embodiment of the present invention.
  • FIG. 3 is a schematic diagram of stents selected according to blood vessel partitions and stent splicing in an embodiment of the present invention
  • FIG. 4 is a schematic diagram of the splicing of a cut-type metal stent and a braided-type metal stent in an embodiment of the present invention
  • FIG. 5 is a schematic diagram of a non-overlapping connection structure of a collar type in an embodiment of the present invention.
  • FIG. 1 is a schematic structural diagram of a method for constructing a vascular stent based on modularization in an embodiment of the present invention.
  • a modularized-based vascular stent construction method includes the following steps:
  • S1 Count the vascular stent data, and use the vascular stent as a module to establish a stent module database;
  • a stent module database including inputting the data of the vascular stent into the database according to the material, structure, function, application scenario and specification classification of the vascular stent; the vascular stent is classified by material, including metal stents and biomaterial stents, and metal stents include cutting-type stents Metal stents and braided metal stents; vascular stents are classified according to surface treatment, including bare type, coated type, and covered type; vascular stents include pure support stents and therapeutic stents according to their functions, and therapeutic stents include coating on the surface of stents. Stents and radioactive stents that carry drugs or use a stent outside the stent to carry therapeutic substances.
  • the diseased blood vessel is divided into a meandering area 1 and a scar area 2, and the meandering area 1 and the scar area 2 are at least one.
  • a braided metal stent is selected for the meandering area 1
  • a cutting-type stent is selected for the scar area
  • the cutting-type stent includes a cutting-type metal stent and a cutting-type biomaterial stent.
  • drug stents can also be used according to the specific conditions of the diseased blood vessels.
  • drug stents with paclitaxel or rapamycin are used to release antibiotics from the stents. It can inhibit the growth of abnormal cells, so that the blood vessels will not be blocked by cells, reducing the possibility of secondary stenosis.
  • a drug stent loaded with antibodies is used to stimulate cells to form epithelial tissue and This reduces the risk of blood clots.
  • the correspondingly selected stents include that the first stent 3 is a cutting metal stent, the second stent 4 is a braided metal stent, and the third stent 5 is a cutting metal stent;
  • the radius of the braided stent is limited on one or both sides. Due to the characteristics of the braided stent, when the radius of the two ends is limited by the mechanical structure, the overall radial support force of the stent will be improved.
  • Improving the radial support force under the condition of flexibility and effective preservation can effectively improve the expansion performance of the whole stent in the blood vessel, and the unique flexibility solves the problem of insufficient support force caused by overlapping stents when multiple stents are used. balance issue.
  • the first bracket 3 and the second bracket 4 and the second bracket 4 and the third bracket 5 are spliced by using a collar-type non-overlapping connection structure, which specifically includes: laser engraving and forming of cutting-type brackets
  • a collar-type non-overlapping connection structure which specifically includes: laser engraving and forming of cutting-type brackets
  • the braided stent fracture is closed by laser welding with a collar-type connection structure.
  • the advantage is that the structural strength of the regular filamentary material after welding with the connecting tube is higher than that of the irregular structure directly welded. Or brazing has higher structural strength and no burrs are generated on the outer surface of the bracket.
  • the hybrid vascular stent with overlapping segments requires a larger crimping force during the process of retracting the sheath, and the handling of the overlapping segment is very difficult.
  • the concept of modular combination of brackets overcomes the functional limitations of a single structural bracket, and overcomes the production limitations of hybrid brackets due to fixed combinations and limited production capacity of the company.
  • the predetermined combination can be produced in advance according to different specifications, and the combined stents of different segment lengths are pre-produced according to the age and sex of the potential patient population.
  • professional medical care can be followed.
  • the direct selection of the assembled stents under the guidance of the personnel greatly shortens the treatment cycle.
  • the method for constructing a vascular stent based on the modularization of the embodiments of the present invention, the modular combination of stents, the flexible deployment of stents for a combination with a high degree of freedom and a high degree of matching, improves the treatment efficiency; It can also be used, and the treatment effect is good; the modular combination of the stent can improve the radial support force and the expansion performance of the stent in the blood vessel under the condition of being flexible and effectively preserved; the loop-type connection structure is adopted for non-overlapping Connection, the structural strength of regular filamentary materials after welding with connecting pipes is higher than that of irregular structures by direct welding or brazing, and the outer surface of the stent does not produce any burrs; there is no waste of overlapping sections, the structure is stable, and the release The process is smoother, the friction in the sheath is less, the risk of breakage is less, and the product life is relatively long.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Physics & Mathematics (AREA)
  • Theoretical Computer Science (AREA)
  • Surgery (AREA)
  • Robotics (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Computer Hardware Design (AREA)
  • Evolutionary Computation (AREA)
  • Geometry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Prostheses (AREA)

Abstract

La présente invention divulgue un procédé de construction d'endoprothèse vasculaire fondé sur la modularisation, comprenant les étapes suivantes : S1 : la collecte de statistiques concernant des données d'endoprothèse vasculaire, l'utilisation d'endoprothèses vasculaires en tant que modules, et l'établissement d'une base de données de modules endoprothèses ; S2 : l'obtention de données de vaisseau sanguin atteints de lésions, et la segmentation d'un vaisseau sanguin atteint de lésions ; S3 : la sélection, en fonction des tailles et des conditions de lésion des segments du vaisseau sanguin atteint de lésions, des modules endoprothèses adaptés aux segments à partir de la base de données de modules endoprothèses ; S4 : l'ajustement des modèles des modules endoprothèses en fonction des conditions de liaison des segments, et la détermination des positions de liaison et des modes d'assemblage des modules endoprothèse des segments ; et S5 : la combinaison des modules endoprothèses des segments en fonction des positions de liaison et les modes d'assemblage des modules endoprothèses des segments pour achever la construction d'une endoprothèse vasculaire. Selon la présente invention, l'endoprothèse est ajustée de manière flexible afin qu'elle soit combinée avec un grand degré de liberté et un grand degré de correspondance, l'efficacité de traitement est améliorée, une structure de liaison de type lanterne est adoptée, une structure de liaison sans chevauchement est stable, le risque de rupture est relativement faible, et la durée de vie d'un produit est relativement longue.
PCT/CN2021/080252 2020-08-07 2021-03-11 Procédé de construction d'endoprothèse vasculaire fondé sur la modularisation Ceased WO2022027963A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB2301841.9A GB2612731B (en) 2020-08-07 2021-03-11 Vascular stent construction method based on modularization

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN202010788708.3 2020-08-07
CN202010788708.3A CN111789703B (zh) 2020-08-07 2020-08-07 基于模块化的血管支架构建方法

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116172645A (zh) * 2023-05-04 2023-05-30 杭州脉流科技有限公司 编织支架的型号推荐方法和计算机设备

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111789703B (zh) * 2020-08-07 2021-09-28 上海恩盛医疗科技有限公司 基于模块化的血管支架构建方法
CN113288534B (zh) * 2021-05-14 2025-10-28 胡佳 拼接式血管支架

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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