WO2022002862A1 - Preparation for enteral nutrition - Google Patents

Abstract

The present invention relates to a combination of (A) a liquid food composition that is neutral in taste and (B) at least one powdered seasoning mixture. Component (A) includes one or more components selected from the group consisting of fatty acids, carbohydrates, proteins, mineral nutrients, vitamins and water, and component (B) contains one or more plant parts of one or more different plants and/or one or more flavor extracts of one or more different plants, and a flavor extract of a plant comprises multiple different chemical compounds.

Description

Preparation for enteral feeding

The invention relates to a new form of preparation / flavor variability for enteral nutrition.

Enteral nutrition is a specific form of nutrition which, together with parenteral nutrition, is referred to as artificial nutrition. Enteral nutrition is nutrition using the intestines. The food is administered, for example, distal to the oral cavity via a probe or via a stoma using the intestinal tract. In general, different nutrients are administered with the help of a tube which is placed in such a way that one end remains outside the body and the other end remains in the digestive tract, for example in the stomach, duodenum, or jejunum. Enteral nutrition can also include the oral route.

However, the disadvantage of previous enteral nutrition is, for example, that only limited flavors and structures are available, and these flavors also taste "artificial", that is to say unnatural, and are therefore not tasty. This can lead to monotony in the patient's menu and thus to lower compliance. This in turn can have negative effects on the nutritional status and thus also on the health of the patient, for example due to insufficient calorie intake.

The present invention is based on the object of providing a wider range of flavors, the different flavors having a better taste (being tastier) and being comparatively easy to handle in use (e.g. during preparation and / or preparation). This object is achieved according to the invention by a combination according to claim 1. Another object is the use of the combination according to the invention according to claim 28 and claim 29.

The combination according to the invention for enteral nutrition consists of two components, (A) a liquid, tasteless,

Food composition; including one or more, preferably all, selected from the group consisting of fatty acids, carbohydrates, proteins, minerals, vitamins and water, and (B) at least one powdery spice mixture containing one or more parts of one or more different plants and / or one or more several aroma extracts from one or more different plants, wherein an aroma extract from one plant comprises several different chemical compounds.

The term "tasteless food composition" is understood to mean a food composition without flavorings and aromas, i.e. without the addition of taste-modifying substances.

Components (A) and (B) are only mixed shortly before they are actually consumed. This creates a natural taste and great variety. The patient can decide which flavor he is hungry for right before consumption. The structure of the seasoning mixes can e.g. be offered in 4 categories: breakfast, soup, main course, dessert. This should suggest a daily routine that is as normal as possible to the patient. The flavors are also focused on tastes known in the first step such as goulash, tomato soup, apple strudel, yoghurt berry muesli, etc., so that the patient can recognize tastes from the time he was still healthy and thus achieve a higher quality of life. The key points are naturalness through the use of spices and flexibility through decoupling the drinking food / basic solution and the taste.

Component (A) of the combination according to the invention is intended to provide the patient (consumer) with all the necessary nutrients, vitamins and minerals. In one embodiment, component (A) can contain one or more fatty acids, these fatty acids being selected from the group consisting of soybean oil, fish oil, extract from coconut oil, medium-chain fatty acids, and mixtures thereof. The fatty acid is preferably an extract from coconut oil.

In one embodiment, the content of medium-chain, preferably saturated, fatty acids in the liquid food composition is at least 50% by weight in the fat content.

In one embodiment, the liquid food composition includes two or more, preferably all, of the following vitamins: vitamins A, D, E, K, B1, B2, B6, B12, C, pantothenic acid, biotin, choline and beta-carotene.

In one embodiment, the liquid food composition includes two or more, preferably all, of the following minerals: potassium, calcium, magnesium, phosphorus, chloride, iron, zinc, copper, iodine, chromium, fluoride, manganese, molybdenum and selenium.

In a further embodiment, the carbohydrates contained in the liquid food composition (A) include one or more of the following: 11-15 g / 100 ml oligo- and polysaccharides, 0.01-0.05 g / 100 ml sucrose and 0.1-0 , 6 g / 100mL maltose.

In a further embodiment, the liquid food composition (A) contains 10-20% by weight of carbohydrates, 1-7% by weight of fatty acids, preferably 4-6% by weight of fatty acids, and 3-20% by weight of proteins.

In a further embodiment, the osmolality of the liquid food composition (A) is 220-260 mOsm / kg, or the osmolarity of the liquid food composition (A) is 480-560 mOsm / L.

In a further embodiment, the energy content of the liquid food composition (A) is 80-180 kcal / 100 ml. The embodiments disclosed herein ensure that the patient (consumer) receives the required nutrients.

In a preferred embodiment, the liquid food composition (A) is a neutral base solution selected from the Nutricomp® series from B. Braun.

It is preferred that the liquid, tasteless food composition is contained in a first container, preferably a bottle, and the spice mixture is contained in a second container, preferably a sachet. This spatial separation of the two components (A) and (B) prevents the liquid food composition and the spice mixture from mixing during storage. This also ensures that the patient can decide which flavor to eat right up until just before they eat.

In a preferred embodiment, the first container contains 150-250 ml of the liquid food composition.

The combination according to the invention of (A) with at least one powdery spice mixture (B) enables an enormous variety of flavors to be offered. In addition, the product development of the seasoning mixes was accompanied by discriminative and descriptive tests by qualified test persons in accordance with DIN EN ISO 8586 and DIN / IDO 22935-1 and assessed using sensors. In particular, the significant improvement in taste was achieved in that the spice mixture contains real spices and not just artificial flavors and / or aromatic substances, as is the case with the ready-mixed drinking foods available on the market. The spice mixture preferably contains only real spices and no artificial aromas and / or artificial aromas at all.

For example, the spice mixture can have a taste of cheese spaetzle with fried onions and at least dextrose, whey powder, fried onions, Contains yeast extract, granulated broth, salt, cheese powder, garlic, anti-caking agents and antioxidants.

In addition, the spice mixture can, for example, have a taste

Tomato soup with basil and contain at least dextrose, tomato, potato starch, yeast extract, granulated broth, basil, salt, anti-caking agents and antioxidants.

In addition, the spice mixture can, for example, have a taste

Have mushroom soup and contain at least dextrose, sweet whey powder, mushroom, mushroom extract, yeast extract, granular broth, salt, caramel syrup, anti-caking agents and antioxidants.

In addition, the spice mixture can, for example, have a taste

Have vegetable curry and contain at least dextrose, vegetables (carrot, celery, leek), sweet whey powder, curry, yeast extract, granular broth, salt, anti-caking agents and antioxidants.

In addition, the spice mixture can have a goulash taste and contain at least dextrose, sweet whey powder, paprika, tomato, yeast extract, granular broth, garlic, onion, herbs, caramel syrup, salt, anti-caking agents and antioxidants.

In addition, the spice mixture can have a spaghetti Bolognese taste and contain at least dextrose, sweet whey powder, paprika, tomato, yeast extract, granular broth, sugar, herbs (thyme, oregano), salt, anti-caking agents and antioxidants.

In addition, the spice mixture can have a taste of wild berries and contain at least dextrose, sweet whey powder, sugar, yoghurt powder, potato starch, beetroot juice powder, blueberries, anti-caking agents and antioxidants. In addition, the spice mixture can have a taste of strawberry pana cotta and contain at least dextrose, sweet whey powder, sugar, yoghurt powder, potato starch, cream powder, beetroot, strawberry powder, anti-caking agents and antioxidants.

In addition, the spice mixture can have a creme caramel taste and contain at least dextrose, sweet whey powder, sugar, caramel sugar syrup, vanilla, egg yolk powder, cream powder, anti-caking agents and antioxidants.

In addition, the spice mixture can have a baked apple taste and contain at least sugar, potato starch, apple, anti-caking agents and antioxidants.

In addition, the spice mixture can have a Mango Lassi taste and contain at least sweet whey powder, sugar, mango powder, potato starch, yoghurt powder, separating agents and coloring agents.

In addition, the spice mixture can have a cheesecake taste and at least sweet whey powder, sugar, yoghurt powder, sour cream powder, vanilla, separating agent; Contain antioxidants and coloring agents.

In addition, the spice mixture can have one, preferably only one, of the following flavors: forest fruit yoghurt, vegetable curry, goulash, creme caramel, strawberry panna cotta, baked apple, mushroom soup, cheese spaetzle, spaghetti Bolognese, and tomato soup with basil.

In addition, the spice mixture can have one, preferably only one, of the following flavors: apple pancakes, apple - streusel cake, apple strudel, baked apples, baked apple - chestnut soup, baked apple - mousse with cranberries, roast goose with apples and onions, fried apple wedges with mulled wine sauce , Filled turkey

Stuffed suckling pig breast, braised goose legs, green ribbon noodles with liver - pear ragout, caramelized apple pie, carrot soup, potato - apple - Puree, children's punch, roasted veal boiled beef with creamed apple, apricot roaster, apricot sorbet, sole on artichoke salad, Auszogne, elderly pancakes, vanilla donuts, fried chicken, tagliatelle with mushrooms and tomatoes, barbarie - roasted duck breast, roasted bear's garlic fillet, bear's garlic fillet Potato - wild garlic - sauce, basil - pesto, basil: horseradish - herb - pesto, peasant duck, stuffed, farmer's omelette with ham, Bavese: plum bavese, bouillabaisse, Bavarian cream, roast pork, sausage salad, cabbage, cabbage with quince, tiramisu, root meat with horseradish , Apple pancakes, pickled berries with vanilla sauce, rhubarb compote, rum stew, berry quark with roasted muesli, mountain cheese, curd cheese patties with lettuce, beer, fingernoodles on pear cream cabbage, fried colorful asparagus vegetables, elder and pear compote, pear red wine -, Mousse with pears, wild boar goulash, Black Forest cherry rte, blue cabbage salad, red cabbage variations, cauliflower vegetables with buttered crumbs, cauliflower soup, Böfflamott, beef stew, beans - tomatoes - vegetables, beans, bouillabaisse, bouillon potatoes, baked apple - chestnuts soup, baked apple - mousse with cranberry soup, broth, broth Minestrone, potato soup, pumpkin soup, herb soup, asparagus soup, carrot-ginger soup, black salsify soup, tomato soup, kohlrabi soup, pea soup, onion soup, bread soup, poultry stew, vegetable stew, barley soup, lentil stew, pichelsteiner stew, table stew / potato stew / goulash soup, winter vegetable stew Beans, potatoes with herb quark, creamed spinach with fried eggs, asparagus with hollandaise sauce, stuffed peppers, cheese, ham and vegetable omelette, cheese spaetzle, ham noodles, spaghetti (with tomato sauce; Bolognese), spinach ravioli, quiche Lorraine, roast pork, pork chops, Wiener schnitzel, meatballs, beef roulades, roast onion roast, roast beef, boiled beef, veal knuckles, veal roast, veal goulash, saffron sausage, roasted cabbage, chicken schnitzel, broth schnitzel, mushrooms , Turkey / turkey, liver sausage, venison ragout, salmon trout, salmon with horseradish sauce / dill sauce / mustard sauce, salmon / cod / pikeperch / perch / sea bream on / with creamed spinach, fried fish, sauerkraut / creamed cabbage, knuckle of pork, beetroot carpaccio with baked black salsify, Avocado - fennel - salad, Rice noodle salad with sugar snap peas and tomatoes, sour pretzel dumplings, spinach dumplings, vegetable strudel, cabbage strudel, truffled potato rösti, Gorgonzola ravioli, sweet potato soup, stuffed peppers with minced meat, cordon bleu, piccata milanese, risotto, veal strudel with meat, veal ragout different variations), zucchini stuffed with prawns, shashlik / vegetable - shashlik.

In a preferred embodiment, the spice mixture does not contain any artificial flavorings. In addition to the variety of flavors already described, this also contributes to a significantly improved taste experience and thus to even greater acceptance by the consumer.

In a further preferred embodiment, the spice mixture contains sweet whey powder and no cold-swelling potato starch. As a result, the solubility of the powdery spice mixture can be further improved. This is particularly the case when the liquid, tasteless food composition is a basic solution from the Nutricomp® series.

In a preferred embodiment, the seasoning mixture is completely soluble in the liquid food composition.

The spice mixture can be present in the container, for example sachet, in any suitable amount. It is particularly preferred if the spice mixture has a mass of 5-20 g per packaging unit (e.g. sachet), since it can then be added more easily to a portion of the liquid food composition.

The combination according to the invention can contain only one powdery seasoning mixture per unit of liquid, tasteless food composition. However, it is also possible that two or more powdery spice mixtures are added, it being possible for the spice mixtures to have the same flavor or different flavors. This is entirely up to the consumer's personal taste.

The present invention also relates to a pack comprising components (A) and (B). The present invention also relates to the use of the combination of (A) and (B) or the pack comprising components (A) and (B) as described herein, for diet management or for the treatment of malnutrition as a result of, for example, loss of appetite, gastroenterological diseases,

Food intolerance, cancer treatment or nutrition with restricted ability to eat or in convalescence.

Finally, the present invention relates to the use of the combination of (A) and (B) or the pack comprising components (A) and (B) as described herein for oral enteral nutrition.

Claims

Claims 1. Combination of (A) a liquid, tasteless food composition; including one or more selected from the group consisting of fatty acids, carbohydrates, proteins, minerals, vitamins and water, (B) and at least one powdery spice mixture containing one or more parts of plants from one or more different plants and / or one or more aroma extracts from one or more different plants, an aroma extract from one plant comprising several different chemical compounds. 2. The combination of claim 1, wherein the liquid, tasteless food composition contains one or more fatty acids selected from the group consisting of soybean oil, fish oil, extract from coconut oil, medium-chain fatty acids, preferably an extract from coconut oil, and mixtures thereof . 3. The combination of claim 1 or 2, wherein the liquid, tasteless food composition is contained in a first container, preferably a bottle, and the seasoning mixture is contained in a second container, preferably a sachet, the first and the second container being the Prevent mixing of the liquid food composition and seasoning mixture during storage. 4. The combination according to one of the preceding claims, wherein the spice mixture has a taste of cheese spaetzle with fried onions and contains at least dextrose, whey powder, fried onions, yeast extract, granular broth, salt, cheese powder, garlic, anti-caking agents and antioxidants. 5. The combination according to any one of the preceding claims, wherein the spice mixture has a taste of tomato soup with basil and at least dextrose, tomato, potato starch, yeast extract, granulated broth, Contains basil, salt, anti-caking agents and antioxidants. 6. The combination according to one of the preceding claims, wherein the spice mixture has a taste of mushroom soup and contains at least dextrose, sweet whey powder, mushroom, mushroom extract, yeast extract, granular broth, salt, caramel syrup, anti-caking agents and antioxidants. 7. The combination according to one of the preceding claims, wherein the spice mixture has a taste of vegetable curry and contains at least dextrose, vegetables (carrot, celery, leek), sweet whey powder, curry, yeast extract, granular broth, salt, anti-caking agents and antioxidants. 8. The combination according to one of the preceding claims, wherein the spice mixture has a taste of goulash and at least dextrose, sweet whey powder, paprika, tomato, yeast extract, granulated broth, garlic, Contains onion, herbs, caramel syrup, salt, anti-caking agents and antioxidants. 9. The combination according to one of the preceding claims, wherein the spice mixture has a taste of spaghetti Bolognese and contains at least dextrose, sweet whey powder, paprika, tomato, yeast extract, granular broth, sugar, herbs (thyme, oregano), salt, anti-caking agents and antioxidants. 10. The combination according to one of the preceding claims, wherein the spice mixture has a taste of wild berries and contains at least dextrose, sweet whey powder, sugar, yoghurt powder, potato starch, beetroot juice powder, blueberries, release agents and antioxidants. 11. The combination according to one of the preceding claims, wherein the spice mixture has a taste of strawberry pana cotta and Contains at least dextrose, sweet whey powder, sugar, yoghurt powder, potato starch, cream powder, beetroot, strawberry powder, anti-caking agents and antioxidants. 12. The combination according to one of the preceding claims, wherein the spice mixture has a creme caramel taste and contains at least dextrose, sweet whey powder, sugar, caramel syrup, vanilla, egg yolk powder, cream powder, anti-caking agents and antioxidants. 13. The combination according to one of the preceding claims, wherein the spice mixture has a taste of baked apples and contains at least sugar, potato starch, apple, anti-caking agents and antioxidants. 14. The combination according to any one of the preceding claims, wherein the osmolality of the liquid food composition (A) is 220-260 mOsm / kg, or the osmolarity of the liquid food composition (A) is 480-560 mOsm / L. 15. The combination according to one of the preceding claims, wherein the energy content of the liquid food composition (A) is 80-180 kcal / 10OmL. 16. The combination according to one of the preceding claims, wherein the content of medium-chain, preferably saturated, fatty acids in the liquid food composition (A) is at least 50% by weight in the fat content. 17. The combination of any preceding claim, wherein the liquid food composition (A) includes the following vitamins: vitamins A, D, E, K, B1, B2, B6, B12, C, pantothenic acid, biotin, choline and beta-carotene . 18. The combination of any preceding claim, wherein the liquid food composition (A) includes the following minerals: Potassium, calcium, magnesium, phosphorus, chloride, iron, zinc, copper, iodine, chromium, fluoride, manganese, molybdenum and selenium. 19. The combination according to any one of the preceding claims, wherein the carbohydrates contained in the liquid food composition (A) include one or more of the following: 11-15 g / 100ml_ oligo- and polysaccharides, 0.01-0.05 g / 100ml_ sucrose and 0.1-0.6 g / 100ml_ maltose. 20. The combination according to one of the preceding claims, wherein in the liquid food composition (A) 10-20% by weight of carbohydrates, 1-7% by weight of fatty acids, preferably 4-6% by weight of fatty acids, and 3-20% by weight Proteins are included. 21. The combination according to one of the preceding claims, wherein the spice mixture does not contain any artificial flavorings. 22. The combination according to one of the preceding claims, wherein the spice mixture has a mass of 5-20 g. 23. The combination according to one of the preceding claims, wherein the spice mixture contains sweet whey powder and no cold-swelling potato starch. 24. The combination according to any one of the preceding claims, wherein the seasoning mixture is completely soluble in the liquid food composition (A). 25. The combination according to one of the preceding claims, wherein the spice mixture has one, preferably only one, of the following flavors: forest fruit yogurt, vegetable curry, goulash, mango lassi, creme caramel, strawberry panna cotta, baked apple, mushroom soup, cheese spaetzle, spaghetti Bolognese, cheesecake, and tomato soup with basil. 26. The combination according to one of the preceding claims, wherein the spice mixture has one, preferably only one, of the following flavors: apple pancakes, apple - streusel - cake, apple strudel, baked apples, baked apple - chestnut soup, baked apple - mousse with cranberries, roast goose with apples and onions, fried apple wedges with mulled wine sauce, stuffed turkey, Stuffed suckling pig breast, braised goose legs, green ribbon noodles with liver - pear ragout, caramelized apple pie, carrot soup, potato - apple puree, children's punch, roasted veal fillet with apple cream, apricot stew, apricot sorbet, vanilla salad on artichoke Fried chicken, ribbon noodles with mushrooms and tomatoes, Barbarie - duck breast, roasted bear paws, wild garlic soup, roasted char fillet on wild garlic - creamed spinach, potato - wild garlic sauce, basil - pesto, basil: horseradish - herb - pesto, farm duck, stuffed, farmer's omelette with ham, Bavese: Plum bavese, bouillabaisse, Bavarian cream, roast pork, sausage salad, cabbage, cabbage with quince, tiramisu, root meat with horseradish, apple pancakes, pickled berries with vanilla sauce, rhubarb compote, rum pot, berry quark with roasted muesli, curd cheese, berry curd with roasted muesli, beer on pears - Cream cabbage, roasted colored asparagus vegetables, elder and pear compote, red wine pears and chocolate mousse with pears, wild boar stew, Black Forest cake, red cabbage salad, red cabbage variations, cauliflower vegetables with butter crumbs, cauliflower soup, Böfflamott, vegetables, beef stew Bouillabaisse, bouillon potatoes, baked apple - chestnut soup, baked apple - mousse with cranberries, consommé, wedding soup, fish soup, semolina dumpling soup, pancake soup, minestrone, potato soup, pumpkin soup, herb soup, cabbage soup, carrot - ginger soup, tomato soup, black salsify soup , Bread soup, poultry stew, vegetable stew, barley soup, lentil stew, Pichelstein stew, winter vegetable stew, goulash / goulash soup / potato goulash, boiled beef soup, lamb stew with beans, potatoes with herb quark, creamed spinach with fried egg, asparagus with sauce, hollandaise, cheese, stuffed According to üseomelette, cheese spaetzle, ham noodles, spaghetti (with tomato sauce; Bolognese), spinach - Maultaschen, Quiche Lorraine, roast pork, pork chops, Wiener schnitzel, meatballs, beef roulades, roast onion, roast beef, boiled beef, veal knuckle, veal roast, veal goulash, Zurich sliced meat, paprika schnitzel, mushroom creamed schnitzel, ragout, Cabbage rolls, chicken fricassee, roast chicken, turkey, liver sausage, Roe ragout, salmon trout, salmon with horseradish sauce / dill sauce / mustard sauce, salmon / cod / pikeperch / perch / sea bream on / with creamed spinach, fried fish, sauerkraut / creamed cabbage, knuckle of pork, beetroot carpaccio with baked black salsify, avocado - fennel salad, rice with sugar snap peas and tomatoes, sour pretzel dumplings, spinach dumplings, vegetable strudel, cabbage strudel, truffled potato rösti, Gorgonzola ravioli, sweet potato soup, stuffed peppers with minced meat, cordon bleu, piccata milanese, veal strudel, risotto and spinach ragout Variations), zucchini stuffed with prawns, shashlik / vegetable - shashlik. 27. The combination according to any one of the preceding claims, wherein the first container of component (A) contains 150-250 mL of the liquid food composition. 28.Pack comprising component (A) and component (B): (A) a liquid, tasteless food composition; including one or more selected from the group consisting of fatty acids, carbohydrates, proteins, minerals, vitamins and water, (B) and at least one powdery spice mixture containing one or more parts of plants from one or more different plants and / or one or more aroma extracts from one or more different plants, an aroma extract from one plant comprising several different chemical compounds. 29. Use of the combination according to one of claims 1-27 or the pack according to claim 28 for diet management in the event of malnutrition, in particular as a result of loss of appetite, gastroenterological diseases, Food intolerance, cancer treatment, or nutrition with restricted ability to eat or in convalescence. 30. Use of the combination according to any one of claims 1-27 or the pack according to claim 28 for enteral, preferably oral enteral, nutrition.