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WO2022091676A1 - Cathéter - Google Patents

Cathéter Download PDF

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Publication number
WO2022091676A1
WO2022091676A1 PCT/JP2021/035822 JP2021035822W WO2022091676A1 WO 2022091676 A1 WO2022091676 A1 WO 2022091676A1 JP 2021035822 W JP2021035822 W JP 2021035822W WO 2022091676 A1 WO2022091676 A1 WO 2022091676A1
Authority
WO
WIPO (PCT)
Prior art keywords
tube
diameter
spherical
catheter
tip
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2021/035822
Other languages
English (en)
Japanese (ja)
Inventor
渉 大塚
勇人 主濱
圭司 鎌田
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Bakelite Co Ltd
Original Assignee
Sumitomo Bakelite Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Bakelite Co Ltd filed Critical Sumitomo Bakelite Co Ltd
Priority to CN202180072434.0A priority Critical patent/CN116348171A/zh
Publication of WO2022091676A1 publication Critical patent/WO2022091676A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes

Definitions

  • the present invention relates to a catheter capable of discharging a drug solution.
  • a catheter may be passed through the lumen of an endoscope when administering a drug solution, a physiological saline solution, or a body fluid (hereinafter referred to as a drug solution, etc.) while confirming a lesion formed in the body on an image.
  • a drug solution a physiological saline solution, or a body fluid (hereinafter referred to as a drug solution, etc.)
  • Patent Document 1 describes a catheter capable of injecting a drug solution or the like in an arbitrary direction when the drug solution or the like is administered into the body under an endoscope.
  • the drug solution is made to collide with the collision surface formed at the tip of the tube of the catheter, and the drug solution or the like is supplied to the lesion through the opening formed at the tip of the tube.
  • the present invention has been made in view of the above-mentioned problems, and an object of the present invention is to provide a catheter capable of appropriately applying a load and displacing a lesion or a peripheral portion thereof. There is something in it.
  • the catheter of the present invention is a catheter that is passed through the lumen of an endoscope and can discharge a drug solution to the digestive tract, and includes a tube through which the drug solution is passed and a ball tip provided at the tip of the tube.
  • the ball tip is formed with a through hole capable of discharging the chemical solution through the tube to the outside, and the ball tip has a spherical portion formed in a partially spherical shape and the spherical portion. It has an insertion portion that extends from the spherical portion and is inserted into the tip of the tube, and is formed harder than the tube.
  • the through hole is formed by the spherical portion and the insertion portion. It is characterized in that it is formed over the above.
  • the catheter of the present invention by providing the ball tip having a spherical portion, it is possible to appropriately apply a load to the lesion portion or its peripheral portion to displace it and support efficient treatment.
  • FIG. 2 is an enlarged view of a portion III of FIG. 2, and is a cross-sectional view showing a state in which an adhesive is contained in the accommodating portion.
  • FIG. 2 is an enlarged view of a portion III of FIG. 2, and is a cross-sectional view showing a state in which an adhesive is contained in the accommodating portion.
  • FIG. 2 is an enlarged view of a portion III of FIG. 2, and is a cross-sectional view showing a state in which an adhesive is contained in the accommodating portion.
  • It is a schematic diagram which shows the state which the washing liquid is being administered from the lumen of an endoscope in order to remove mucus.
  • It is a schematic diagram which shows the state which presses a healthy mucous membrane around a lesion part by a catheter.
  • FIG. 1 is a schematic view showing a catheter 1 according to the present embodiment
  • FIG. 2 is a cross-sectional view showing a ball tip 2 attached to a tip portion of a tube 1c
  • FIG. 3 is an enlarged view of a portion III of FIG. It is sectional drawing which shows the state which the adhesive 6 is accommodated in the accommodating part 5.
  • the catheter 1 is passed through the lumen 10a of the endoscope 10 (see FIGS. 4 and 5) and can discharge the drug solution to the gastrointestinal tract 11 (see FIGS. 4 and 5). ..
  • the catheter 1 includes a tube 1c through which a drug solution is passed and a ball tip 2 provided at a tip portion 1e of the tube 1c.
  • the ball tip 2 is formed with a through hole 2a capable of discharging the chemical solution that has passed through the tube 1c to the outside.
  • the ball tip 2 has a spherical portion 3 formed in a partially spherical shape and an insertion portion 4 extending from the spherical portion 3 and inserted into the tip portion 1e of the tube 1c, and is harder than the tube 1c. Is formed in.
  • the through hole 2a is formed over the spherical portion 3 and the insertion portion 4.
  • Discharge includes “injection” to be supplied in liquid form, “spray” to be supplied in the form of mist, and “dropping” to be supplied in small amounts.
  • the tube 1c may be made of only resin or rubber, or may contain a metal material that enhances rigidity.
  • the ball tip 2 may be formed to be harder than at least the tip portion 1e of the tube 1c.
  • the ball tip 2 since the ball tip 2 has the spherical portion 3, when the lesion portion 11b or the peripheral portion thereof is pressed, the contact area is increased and a local load is not applied. .. Therefore, according to the catheter 1, an appropriate load can be applied to the lesion portion 11b or a peripheral portion thereof to support efficient treatment.
  • the ball tip 2 presses the lesion portion 11b or its peripheral portion, and in a state where the lesion portion 11b or its peripheral portion is displaced, a chemical solution is supplied, and the entire shape and the partial shape of the lesion portion 11b are suitably imaged by the endoscope 10. Can be done.
  • the catheter 1 includes a connector 1a, a handle 1b connected to the connector 1a and held by the user, and a tube 1c extending long from the handle 1b, in order from the proximal end side.
  • a ball tip 2 inserted into the tip of the tube 1c is provided.
  • the effective length of the catheter 1 according to the present embodiment is, for example, about 2750 mm.
  • a syringe (not shown) that contains the chemical solution and can be extruded is connected to the connector 1a in order to discharge the chemical solution via the handle 1b, the tube 1c, and the ball tip 2.
  • thermoplastic polymer material can be used as the main material of the tube 1c.
  • thermoplastic polymer material examples include polyimide (PI), polyamideimide (PAI), polyethylene terephthalate (PET), polyethylene (PE), polyamide (PA), polyamide elastomer (PAE), and polyether blockamide (PEBA).
  • PI polyimide
  • PAI polyamideimide
  • PET polyethylene
  • PA polyamide
  • PAE polyamide elastomer
  • PEBA polyether blockamide
  • nylon elastomer polyurethane
  • EVA ethylene-vinyl acetate resin
  • PVC polyvinyl chloride
  • PP polypropylene
  • the ball tip 2 is formed with a through hole 2a capable of discharging the chemical solution that has passed through the tube 1c to the outside, and the spherical portion 3 formed in a partially spherical shape and the spherical portion 3 It has an insertion portion 4 extending and being inserted into the tip portion 1e of the tube 1c.
  • the ball chip 2 according to the present embodiment is made of stainless steel.
  • the ball tip 2 may be harder than the tube 1c and may be made of a metal material such as nitinol or a resin material other than stainless steel.
  • the maximum diameter of the spherical portion 3 of the ball chip 2 according to the present embodiment is about 2.7 mm.
  • the diameter of the lumen 10a of the endoscope 10 (see FIG. 4) through which the tube 1c and the ball tip 2 are passed is about 2.8 mm or more, which is larger than the maximum diameter of the spherical portion 3.
  • the insertion portion 4 is provided with a shaft portion 4a extending in the insertion direction into the tube 1c and a shaft portion 4a at the insertion destination rather than the shaft portion 4a, and at least one of the shaft portions 4a.
  • a large diameter portion 4b formed to have a diameter larger than the outer diameter of the portion is provided.
  • an accommodating portion 5 for accommodating the adhesive 6 is formed between the shaft portion 4a, the large diameter portion 4b, the spherical portion 3, and the tube 1c.
  • the accommodating portion 5 is filled with the adhesive 6.
  • the adhesive 6 can be accommodated in the accommodating portion 5 provided in the insertion portion 4 of the ball tip 2, and the adhesive 6 and the shaft portion 4a, the large diameter portion 4b, the spherical portion 3 and the tube 1c are included. , The contact area can be suitably secured. Therefore, it is possible to strengthen the bond between the respective parts via the adhesive 6. As long as the connection between each of these portions is strong, the insertion portion 4 does not necessarily have to have the large diameter portion 4b, and only the straight tubular shaft portion 4a may be formed.
  • the large diameter portion 4b has a return portion 4e on the outer peripheral surface.
  • the return portion 4e has a diameter-expanded portion 4f that expands radially outward from the shaft portion 4a and abuts on the inner wall 1f of the tube 1c, and a diameter-reduced portion that decreases in diameter from the diameter-expanded portion 4f toward the end of the insertion destination. It is composed of 4 g of a portion.
  • the large diameter portion 4b is configured in this way, the ball tip 2 can be easily inserted into the tube 1c from the insertion portion 4 by the reduced diameter portion 4g of the return portion 4e. Further, the enlarged diameter portion 4f of the return portion 4e that abuts on the inner wall 1f of the tube 1c makes it difficult for the ball tip 2 to come off from the tube 1c. If the insertion portion 4 of the ball tip 2 can be smoothly inserted into the tube 1c, the large diameter portion 4b may not be provided with the return portion 4e. That is, for example, the large diameter portion 4b may have a straight cylinder shape with an R chamfered tip portion.
  • the shaft portion 4a has a tapered portion 4c whose diameter decreases toward the insertion destination and a tube 1c from the end portion of the insertion destination in the tapered portion 4c to the large diameter portion 4b. It is composed of a tubular portion 4d extending in parallel in the axial direction and a tubular portion 4d.
  • a wide radial region for accommodating the adhesive 6 can be secured on the radial outer side of the tubular portion 4d.
  • the tapered portion 4c allows the adhesive to be accommodated in a wide range in the axial direction, and the radial gap between the inner wall 1f of the tube 1c and the insertion portion 4 can be narrowed as it approaches the end face 1d. .. Therefore, it is possible to prevent the ball tip 2 from wobbling with respect to the tube 1c.
  • the shaft portion 4a is formed in this way, for example, before the ball tip 2 is inserted into the tube 1c, the adhesive 6 applied to the tube portion 4d in large quantities is inserted, and the ball tip 2 is inserted into the tube 1c. Occasionally, it can be stretched from the tubular portion 4d to the tapered portion 4c. Therefore, an appropriate amount of the adhesive 6 can be accommodated in the area of the accommodating portion 5.
  • the accommodating portion 5 is formed between the return portion 4e and the spherical portion 3.
  • the adhesive 6 is accommodated between the return portion 4e and the spherical portion 3 in contact with the inner wall 1f of the tube 1c, whereby the inside of the tube 1c and the through hole 2a of the tube 1c are formed. It is possible to prevent the adhesive 6 from coming into contact with the passing chemical solution.
  • the spherical portion 3 projects outward from the tube 1c in the radial direction with respect to the tube 1c.
  • the portion of the spherical portion 3 protruding from the tube 1c is a partial spherical portion formed with a diameter larger than the outer diameter of the tube 1c when viewed from a direction orthogonal to the axial direction of the tube 1c.
  • the spherical portion 3 protrudes from the tube 1c, it is easy to press and displace the lesion portion 11b or its peripheral portion by the spherical portion 3.
  • the portion of the spherical portion 3 protruding from the tube 1c is a partial spherical portion formed with a diameter larger than the outer diameter of the tube 1c, the lesion portion 11b or its peripheral portion is efficiently treated. can do.
  • the spherical portion 3 protruding from the tube 1c can increase the contact area when pressing against the lesion portion 11b or its peripheral portion, and efficiently without applying a local load. It can be treated (displacement of lesion 11b or its periphery). This characteristic of the spherical portion 3 is particularly effective when the overall shape of the lesion portion 11b cannot be confirmed by the endoscope 10 due to the folds 11c (see FIG. 4) and the lesion portion 11b or the peripheral portion needs to be displaced. ..
  • the spherical portion 3 has a contact surface 3a that is abutted against the end surface 1d of the tube 1c.
  • the outer surface of the spherical portion 3 is continuously formed with respect to the outer surface of the tube 1c in a state where the end surface 1d of the tube 1c and the contact surface 3a are in contact with each other.
  • the outer surface of the spherical portion 3 is" continuously formed "with respect to the outer surface of the tube 1c means that the outer surface of the spherical portion 3 abuts on the radial outer edge of the end surface 1d of the tube 1c. It means that the portion (the radial outer edge of the contact surface 3a) is in the vicinity of the radial outer edge of the end surface 1d of the tube 1c and is at a position facing the axial direction of the tube 1c. ..
  • a slight gap caused by a fitting error or a dimensional error between the tube 1c and the spherical portion 3 or a slight gap created by chamfering only one of the tube 1c or the spherical portion 3 is formed.
  • the outer surface of the spherical portion 3 is continuously formed with respect to the outer surface of the tube 1c, it is possible to suppress foreign matter from entering between the tube 1c and the ball tip 2. ..
  • FIG. 4 is a schematic view showing a state in which the washing liquid 7 is administered from the lumen 10a of the endoscope 10 in order to remove mucus (not shown).
  • FIG. 5 is a schematic view showing a state in which the catheter 1 presses the healthy mucous membrane (inner wall 11a of the gastrointestinal tract 11) around the lesion portion 11b.
  • the operator removes the mucus (not shown) around the lesion 11b before administering the drug solution to the lesion 11b.
  • the mucus is removed by discharging or directly sucking the cleaning liquid 7 from the lumen 10a of the endoscope 10.
  • the catheter 1 may be projected from the lumen 10a, and the mucus may be removed by discharging or directly sucking the cleaning liquid 7 from the through hole 2a of the ball tip 2 at the tip of the catheter 1. Further, the mucus may be removed by lightly rubbing the periphery of the lesion portion 11b with the ball tip 2 at the tip portion of the catheter 1.
  • a solution containing indigo carmine as a solute (drug) that makes the unevenness on the surface of the lesion portion 11b conspicuous by coloring is used.
  • an ampoule having a volume of 5 mL containing a 0.4% solution obtained by diluting indigo carmine 4 to 5 times is used.
  • the drug is not limited to indigo carmine.
  • a solution containing crystal violet (pioctanin) that makes the pattern on the surface of the lesion portion 11b stand out is used as the drug solution mainly dropped on the lesion portion 11b of the large intestine.
  • crystal violet crystal violet
  • a 1% crystal violet solution is stored and further diluted about 20 times before use.
  • the various components of the catheter of the present invention do not have to be individually independent.
  • a plurality of components are formed as one member, one component is formed of a plurality of members, one component is a part of another component, and one of the components. It is permissible that a part and a part of other components overlap with each other.
  • a catheter that can be passed through the lumen of an endoscope to eject a drug solution into the gastrointestinal tract.
  • the tube through which the drug solution is passed and With a ball tip provided at the tip of the tube,
  • the ball tip is formed with a through hole capable of discharging the chemical solution through the tube to the outside.
  • the ball tip has a spherical portion formed in a partially spherical shape and an insertion portion extending from the spherical portion and being inserted into the tip portion of the tube, and is formed harder than the tube.
  • Has been A catheter characterized in that the through hole is formed over the spherical portion and the insertion portion.
  • the insertion portion is provided with a shaft portion extending in the insertion direction into the tube and an insertion destination beyond the shaft portion, and is formed to have a diameter larger than the outer diameter of at least a part of the shaft portion. With a large diameter part, An accommodating portion for accommodating the adhesive is formed between the shaft portion, the large diameter portion, the spherical portion, and the tube.
  • the shaft portion has a tapered portion whose diameter decreases toward the insertion destination, and a tubular portion extending in parallel with the axial direction of the tube from the end portion of the insertion destination in the tapered portion to the large diameter portion.
  • the catheter according to (2) which is configured.
  • the insertion portion is provided with a shaft portion extending in the insertion direction into the tube and an insertion destination beyond the shaft portion, and is formed to have a diameter larger than the outer diameter of at least a part of the shaft portion.
  • the large diameter portion has a return portion on the outer peripheral surface and has a return portion on the outer peripheral surface.
  • the return portion has a diameter-expanded portion that expands radially outward from the shaft portion and abuts on the inner wall of the tube, and a diameter-reduced portion that decreases in diameter from the diameter-expanded portion toward the end of the insertion destination.
  • the catheter according to any one of (1) to (3), which is composed of.
  • the catheter according to (6), wherein the portion of the spherical portion protruding from the tube is a partial spherical portion formed with a diameter larger than the outer diameter of the tube when viewed from a direction orthogonal to the axial direction of the tube. .. (8)
  • the spherical portion has an abutting surface that is abutted against the end surface of the tube.
  • the outer surface of the spherical portion is continuously formed with respect to the outer surface of the tube in a state where the end surface of the tube and the contact surface are in contact with each other, whichever is one of (1) to (7).

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

Ce cathéter est inséré dans une lumière d'un endoscope et est capable de décharger un médicament liquide dans le tractus digestif. Le cathéter comprend un tube à travers lequel passe le médicament liquide et une pointe de bille disposée sur l'extrémité avant du tube. Un trou traversant dans lequel le médicament liquide qui a traversé le tube peut être évacué vers l'extérieur est formé dans la pointe de bille. La pointe de bille a une section sphérique formée dans une forme partiellement sphérique et une section d'insertion qui s'étend à partir de la section sphérique et est insérée dans l'extrémité avant du tube. La pointe de bille est formée de manière à être plus dure que le tube. Le trou traversant est formé à travers la section sphérique et la section d'insertion.
PCT/JP2021/035822 2020-11-02 2021-09-29 Cathéter Ceased WO2022091676A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202180072434.0A CN116348171A (zh) 2020-11-02 2021-09-29 导管

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2020183762A JP7571474B2 (ja) 2020-11-02 2020-11-02 カテーテル
JP2020-183762 2020-11-02

Publications (1)

Publication Number Publication Date
WO2022091676A1 true WO2022091676A1 (fr) 2022-05-05

Family

ID=81383708

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2021/035822 Ceased WO2022091676A1 (fr) 2020-11-02 2021-09-29 Cathéter

Country Status (3)

Country Link
JP (1) JP7571474B2 (fr)
CN (1) CN116348171A (fr)
WO (1) WO2022091676A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08187292A (ja) * 1995-01-09 1996-07-23 Olympus Optical Co Ltd カテーテル
JPH11319104A (ja) * 1998-05-19 1999-11-24 Olympus Optical Co Ltd 内視鏡用処置具
JP2012071052A (ja) * 2010-09-29 2012-04-12 Terumo Corp 留置針および留置針の製造方法
WO2012115363A2 (fr) * 2011-02-22 2012-08-30 주식회사 세양메디칼 Outil multi-procédure pour la couche sous-muqueuse endoscopique qui exécute une pluralité de modes dans un dispositif par l'intermédiaire d'un module multi-procédure
US20130072958A1 (en) * 2010-05-07 2013-03-21 Entellus Medical, Inc. Sinus balloon dilation catheters and sinus surgury tools
JP2020519368A (ja) * 2017-05-11 2020-07-02 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 管腔内撮像デバイス用の支持部材並びに関連デバイス、システム及び方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9827003B2 (en) * 2011-02-15 2017-11-28 Smith & Nephew, Inc. Arthroscopic resection device

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08187292A (ja) * 1995-01-09 1996-07-23 Olympus Optical Co Ltd カテーテル
JPH11319104A (ja) * 1998-05-19 1999-11-24 Olympus Optical Co Ltd 内視鏡用処置具
US20130072958A1 (en) * 2010-05-07 2013-03-21 Entellus Medical, Inc. Sinus balloon dilation catheters and sinus surgury tools
JP2012071052A (ja) * 2010-09-29 2012-04-12 Terumo Corp 留置針および留置針の製造方法
WO2012115363A2 (fr) * 2011-02-22 2012-08-30 주식회사 세양메디칼 Outil multi-procédure pour la couche sous-muqueuse endoscopique qui exécute une pluralité de modes dans un dispositif par l'intermédiaire d'un module multi-procédure
JP2020519368A (ja) * 2017-05-11 2020-07-02 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 管腔内撮像デバイス用の支持部材並びに関連デバイス、システム及び方法

Also Published As

Publication number Publication date
CN116348171A (zh) 2023-06-27
JP2022073639A (ja) 2022-05-17
JP7571474B2 (ja) 2024-10-23

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