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WO2021222964A3 - Immunogenic complexes and methods of producing and using the same - Google Patents

Immunogenic complexes and methods of producing and using the same Download PDF

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Publication number
WO2021222964A3
WO2021222964A3 PCT/AT2021/060160 AT2021060160W WO2021222964A3 WO 2021222964 A3 WO2021222964 A3 WO 2021222964A3 AT 2021060160 W AT2021060160 W AT 2021060160W WO 2021222964 A3 WO2021222964 A3 WO 2021222964A3
Authority
WO
WIPO (PCT)
Prior art keywords
immunogenic complexes
producing
methods
same
complexes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/AT2021/060160
Other languages
French (fr)
Other versions
WO2021222964A2 (en
Inventor
Alireza ESLAMIAN
Martin SCHIFKO
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ESS Holding GmbH
Original Assignee
ESS Holding GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ESS Holding GmbH filed Critical ESS Holding GmbH
Publication of WO2021222964A2 publication Critical patent/WO2021222964A2/en
Publication of WO2021222964A3 publication Critical patent/WO2021222964A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/385—Haptens or antigens, bound to carriers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4726—Lectins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/64—Medicinal preparations containing antigens or antibodies characterised by the architecture of the carrier-antigen complex, e.g. repetition of carrier-antigen units

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Virology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to a method of forming immunogenic complexes, in particular a method of coating pathogens or fragments thereof with hMBL or portions thereof. Furthermore, the invention relates to said immunogenic complexes, pharmaceutical compositions comprising said immunogenic complexes, in particular vaccines comprising said immunogenic complexes, and the use of the immunogenic complexes and the pharmaceutical compositions.
PCT/AT2021/060160 2020-05-07 2021-05-07 Immunogenic complexes and methods of producing and using the same Ceased WO2021222964A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT503942020 2020-05-07
ATA50394/2020 2020-05-07

Publications (2)

Publication Number Publication Date
WO2021222964A2 WO2021222964A2 (en) 2021-11-11
WO2021222964A3 true WO2021222964A3 (en) 2021-12-16

Family

ID=75953804

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AT2021/060160 Ceased WO2021222964A2 (en) 2020-05-07 2021-05-07 Immunogenic complexes and methods of producing and using the same

Country Status (1)

Country Link
WO (1) WO2021222964A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002041913A1 (en) * 2000-11-27 2002-05-30 Jens Christian Jensenius Collectins as adjuvants
WO2017143024A2 (en) * 2016-02-16 2017-08-24 President And Fellows Of Harvard College Pathogen vaccines and methods of producing and using the same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002041913A1 (en) * 2000-11-27 2002-05-30 Jens Christian Jensenius Collectins as adjuvants
WO2017143024A2 (en) * 2016-02-16 2017-08-24 President And Fellows Of Harvard College Pathogen vaccines and methods of producing and using the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VALDIMARSSON H ET AL: "RECONSTITUTION OF OPSONIZING ACTIVITY BY INFUSION OF MANNAN-BINDINGLECTIN (MBL) TO MBL-DEFICIENT HUMANS", SCANDINAVIAN JOURNAL OF IMMUNOLOGY, BLACKWELL SCIENCE PUBL., OXFORD, GB, vol. 48, no. 2, 1 August 1998 (1998-08-01), pages 116 - 123, XP000911946, ISSN: 0300-9475, DOI: 10.1046/J.1365-3083.1998.00396.X *

Also Published As

Publication number Publication date
WO2021222964A2 (en) 2021-11-11

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