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WO2021241838A1 - Dispositif de traitement de maladies bactériennes et virales par stimulation électrique - Google Patents

Dispositif de traitement de maladies bactériennes et virales par stimulation électrique Download PDF

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Publication number
WO2021241838A1
WO2021241838A1 PCT/KR2021/000822 KR2021000822W WO2021241838A1 WO 2021241838 A1 WO2021241838 A1 WO 2021241838A1 KR 2021000822 W KR2021000822 W KR 2021000822W WO 2021241838 A1 WO2021241838 A1 WO 2021241838A1
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WO
WIPO (PCT)
Prior art keywords
electrical stimulation
virus
bacterial
unit
user
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2021/000822
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English (en)
Korean (ko)
Inventor
연성찬
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SNU R&DB Foundation
Original Assignee
Seoul National University R&DB Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR1020210005928A external-priority patent/KR20210146775A/ko
Application filed by Seoul National University R&DB Foundation filed Critical Seoul National University R&DB Foundation
Publication of WO2021241838A1 publication Critical patent/WO2021241838A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36031—Control systems using physiological parameters for adjustment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002—Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/0205—Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/02—Detecting, measuring or recording for evaluating the cardiovascular system, e.g. pulse, heart rate, blood pressure or blood flow
    • A61B5/024—Measuring pulse rate or heart rate
    • A61B5/02438—Measuring pulse rate or heart rate with portable devices, e.g. worn by the patient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14542—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring blood gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/48—Other medical applications
    • A61B5/4836—Diagnosis combined with treatment in closed-loop systems or methods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802—Sensor mounted on worn items
    • A61B5/681—Wristwatch-type devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/74—Details of notification to user or communication with user or patient; User input means
    • A61B5/742—Details of notification to user or communication with user or patient; User input means using visual displays
    • A61B5/7445—Display arrangements, e.g. multiple display units
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/20—Applying electric currents by contact electrodes continuous direct currents
    • A61N1/22—Electromedical belts, e.g. neck chains, armbands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/321—Electromedical belts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/18—Applying electric currents by contact electrodes
    • A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36—Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014—External stimulators, e.g. with patch electrodes
    • A61N1/3603—Control systems
    • A61N1/36034—Control systems specified by the stimulation parameters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N2/00—Magnetotherapy
    • A61N2/02—Magnetotherapy using magnetic fields produced by coils, including single turn loops or electromagnets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/0271—Thermal or temperature sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
    • A61B2562/02—Details of sensors specially adapted for in-vivo measurements
    • A61B2562/029—Humidity sensors

Definitions

  • It relates to a device for treating bacterial and viral diseases using electrical stimulation.
  • a virus is an infectious agent consisting of a genetic material consisting of DNA or RNA and a protein.
  • the size varies depending on the type, but is usually between 10 and 1000 nm. Since it cannot metabolize itself, its DNA or RNA penetrates into host cells such as bacteria, animals, and plants, and then replicates them using the host cell's organelles and produces viruses like itself, which usually results in the host cells are destroyed
  • An object of the present invention is to provide an apparatus for treating bacterial and viral diseases using electrical stimulation.
  • An apparatus for treating bacterial and viral diseases includes: an electrical stimulation generating unit that sequentially generates electrical stimulation of different frequencies; and an electrode unit that sequentially applies the generated electrical stimulation of different frequencies to the user's body by contacting the user's body with a bacterial or viral disease. may include.
  • the bacterial or viral disease may include rhinitis.
  • the electrical stimulation includes a voltage or current, the voltage is greater than 0 and less than 300V, the current is greater than 0 and less than 12mA, the frequency of the electrical stimulation is greater than or equal to 1Hz and less than or equal to 100GHz, and the duration of each frequency is greater than or equal to 1 minute 20 minutes or less, and the waveform of electrical stimulation may be any one of direct current, alternating current, and pulsation, or a combination of two or more.
  • the electrical stimulation generating unit may sequentially generate the electrical stimulation of the different frequencies with reference to a pre-stored frequency list.
  • the apparatus for treating bacterial and viral diseases may further include a sensor unit for measuring a temperature or humidity of a user's skin in contact with the electrode unit.
  • the apparatus for treating bacterial and viral diseases includes: a control unit that stops the operation of the electrical stimulation generating unit when the measured temperature or humidity is above a set level; may further include.
  • the apparatus for treating bacterial and viral diseases includes: a band unit on which the electrode unit is mounted and worn on the user's body to contact the user's body; and a body part on which the electrical stimulation generating part is mounted and connected to the band part through an electric wire; may include.
  • the band unit is configured in the form of a wrist band or ankle band and may be worn on the user's wrist or ankle.
  • the bacterial disease may include a disease caused by any one of pneumococcus, aeruginosa, gonorrhea, brucellosis, Escherichia coli, tuberculosis, typhoid, cholera, syphilis, Staphylococcus aureus, Staphylococcus aureus, and Salmonella.
  • the viral diseases include human papillomavirus, Ebola virus, coronavirus, SARS virus, measles virus, human immunodeficiency virus (HIV), Japanese encephalitis virus, hepatitis A, B, C virus, herpes virus, rabies virus, influenza virus, rhinovirus, respiratory syncytial virus, flu virus, Zika virus, West Nile virus, smallpox virus and polio virus.
  • human papillomavirus Ebola virus, coronavirus, SARS virus, measles virus, human immunodeficiency virus (HIV), Japanese encephalitis virus, hepatitis A, B, C virus, herpes virus, rabies virus, influenza virus, rhinovirus, respiratory syncytial virus, flu virus, Zika virus, West Nile virus, smallpox virus and polio virus.
  • FIG. 1 is a block diagram illustrating an apparatus for treating bacterial and viral diseases using electrical stimulation according to an exemplary embodiment.
  • Fig. 2 is a block diagram showing an apparatus for treating bacterial and viral diseases using electrical stimulation according to an exemplary embodiment.
  • FIG. 3 is a diagram showing an embodiment of an apparatus for treating bacterial and viral diseases using electrical stimulation according to an exemplary embodiment.
  • FIG. 4 is a view illustrating a state in which the band unit of FIG. 3 is worn on the user's wrist.
  • FIG. 5 is a view illustrating a state in which the band portion of FIG. 3 is worn on the user's ankle.
  • FIG. 6 is a rear view of the main body of FIG. 3 .
  • FIG. 7 is a view showing the results of an experiment according to Experimental Example 1. Referring to FIG.
  • each step may occur differently from the specified order unless a specific order is clearly stated in context. That is, each step may be performed in the same order as specified, may be performed substantially simultaneously, or may be performed in the reverse order.
  • the classification of the constituent units is merely classified according to the main function that each constituent unit is responsible for. That is, two or more components may be combined into one component, or one component may be divided into two or more for each more subdivided function. In addition to the main functions that each component unit is responsible for, some or all of the functions of other components may be additionally performed. may be performed. Each component may be implemented as hardware or software, or may be implemented as a combination of hardware and software.
  • FIG. 1 is a block diagram illustrating an apparatus for treating bacterial and viral diseases using electrical stimulation according to an exemplary embodiment.
  • an apparatus 100 for treating bacterial and viral diseases using electrical stimulation may include an electrode unit 110 , an electrical stimulation generating unit 120 , and a control unit 130 . have.
  • the electrode unit 110 may apply electrical stimulation to the user's body by contacting the user's body with a bacterial or viral disease.
  • the user's body may include, but is not limited to, a wrist, an ankle, a forearm, a calf, a thigh, a finger, a waist, a neck, and the like.
  • electrical stimulation includes voltage or current, and can deliver a microcurrent of less than 1000 ⁇ A to the user's body through electrical stimulation.
  • Bacterial or viral diseases may include rhinitis.
  • bacterial diseases include, for example, diseases resulting from pneumococcus, aeruginosa, gonorrhea, brucellosis, Escherichia coli, mycobacterium tuberculosis, typhoid bacillus, cholera, syphilis, Staphylococcus aureus, Staphylococcus aureus and Salmonella, and the like.
  • Sexually transmitted diseases include, for example, human papillomavirus, Ebola virus, coronavirus, SARS virus, measles virus, human immunodeficiency virus (HIV), Japanese encephalitis virus, hepatitis A, B, C virus, herpes virus, rabies virus, influenza virus, Rhino virus, respiratory syncytial virus (RSV), flu virus, Zika virus, West Nile virus, smallpox virus, polio virus, and the like.
  • human papillomavirus is eg.
  • the coronavirus is, for example, SARS-CoV , MERS-CoV, SARS-CoV-2 and SARS-like-CoV may be included.
  • the electrode unit 110 may include a plurality of electrodes contacting different body regions of the user, and each electrode is a conductive material through which electricity can flow, for example, a conductive metal, a conductive rubber, and a conductive material. It may be made of plastic or the like.
  • the electrical stimulation generating unit 120 may sequentially generate electrical stimulation of different frequencies according to the control of the control unit 130 and transmit it to the electrode unit 110 .
  • the voltage may be greater than 0 and less than 300V
  • the current may be greater than 0 and less than 12mA
  • the frequency may be greater than or equal to 1Hz and less than or equal to 100GHz
  • the duration of each frequency may be greater than or equal to 1 minute and less than or equal to 20 minutes.
  • the waveform of the electrical stimulation may be any one of direct current, alternating current, and pulsation (monophasic or biphasic) or a combination of two or more.
  • the electrical stimulation generating unit 120 may use a pre-stored frequency list. In this case, the electrical stimulation generating unit 120 may sequentially and repeatedly generate electrical stimulation of each frequency in the frequency list.
  • the electrical stimulation generating unit 120 generates electrical stimulation of the first frequency for 1 minute and delivers it to the electrode unit 110 , and then generates the electrical stimulation of the second frequency for 1 minute to the electrode unit 110 . ), and then generates electrical stimulation of the third frequency for 1 minute and delivers it to the active unit 110 , and then again generates electrical stimulation of the first frequency for 1 minute to deliver to the electrode unit 110 .
  • electrical stimulation of each frequency in the frequency list may be sequentially and repeatedly generated and applied to the user through the electrode unit 110 .
  • the electrical stimulation generating unit 120 may generate electrical stimulation using a power source or a battery provided inside or outside the disease treatment apparatus 100 .
  • the controller 130 may control the overall operation of the disease treatment apparatus 100 . Also, the controller 130 may perform various operations performed by the disease treatment apparatus 100 and process data. In addition, the controller 130 may be configured to drive an operating system (OS), an application, and the like for driving the disease treatment apparatus 100 . For example, when a user command or a predetermined event occurs, the control unit 130 may control the electrical stimulation generating unit 120 to sequentially generate electrical stimulation of different frequencies and deliver it to the electrode unit 110 .
  • OS operating system
  • the control unit 130 may control the electrical stimulation generating unit 120 to sequentially generate electrical stimulation of different frequencies and deliver it to the electrode unit 110 .
  • Fig. 2 is a block diagram showing an apparatus for treating bacterial and viral diseases using electrical stimulation according to an exemplary embodiment.
  • the disease treatment apparatus 200 includes an electrode unit 110 , an electrical stimulation generating unit 120 , a control unit 130 , a first sensor unit 210 , a second sensor unit 220 , and an input unit ( 230 ), a storage unit 240 , a communication unit 250 , and an output unit 260 .
  • the electrode unit 110 , the electrical stimulation generating unit 120 , and the control unit 130 are the same as those described above with reference to FIG. 1 , detailed descriptions thereof will be omitted in the overlapping range.
  • the first sensor unit 210 may measure environmental information of the user's skin.
  • the environmental information may include temperature and humidity.
  • the first sensor unit 210 may include a temperature sensor and a humidity sensor.
  • the control unit 130 stops the operation of the electrical stimulation generating unit 120, or when at least one of the temperature and humidity measured by the first sensor unit 210 is higher than a set level due to heat and sweat generated in the user's body, The user may be notified that the measured value of the first sensor unit 210 is equal to or greater than a set level through the output unit 260, which will be described later.
  • the second sensor unit 220 may measure a biosignal by contacting the user's body.
  • the biosignal may include body temperature, heartbeat, pulse, blood pressure, electrocardiogram, and the like.
  • the second sensor unit 220 may include a body temperature sensor, a heart rate sensor, a pulse sensor, a blood pressure sensor, and an electrocardiogram sensor.
  • the user's bio-signals measured by the second sensor unit 220 are transmitted to an external device through the communication unit 250 to be described later. It may be used for monitoring the user's health condition.
  • the input unit 230 may receive various manipulation signals and information from the user.
  • the input unit 230 includes a key pad, a dome switch, a touch pad, a jog wheel, a jog switch, and a H/W button. and the like.
  • the touch pad forms a layer structure with the display, it may be referred to as a touch screen.
  • the storage unit 240 may store programs or commands for the operation of the disease treatment apparatus 200 , and may store data input/output to/from the disease treatment apparatus 200 , processed data, and the like.
  • the storage unit 240 stores information necessary for generating electrical stimulation used for treatment of bacterial or viral diseases, such as voltage magnitude, current magnitude, frequency list, duration of each frequency, electrical stimulation waveform (eg, It can store direct current, alternating current, pulsation (monophasic or biphasic, etc.), etc.
  • the storage unit 240 includes the environmental information measured by the first sensor unit 210 and the second sensor unit ( 210) may store the measured biosignal.
  • the storage unit 240 includes a flash memory type, a hard disk type, a multimedia card micro type, a card type memory (eg, SD or XD memory, etc.), RAM (Random Access Memory, RAM), SRAM (Static Random Access Memory), ROM (Read Only Memory, ROM), EEPROM (Electrically Erasable Programmable Read Only Memory), PROM (Programmable Read Only Memory), magnetic memory, magnetic disk, optical disk and at least one type of storage medium.
  • the disease treatment apparatus 200 may operate an external storage medium such as a web storage that performs a storage function of the storage unit 240 on the Internet.
  • the communication unit 250 may communicate with an external device.
  • the communication unit 250 transmits data input to the disease treatment device 200, stored data, processed data, etc. to an external device, or receives various data to be used for treatment of bacterial or viral diseases from the external device.
  • the communication unit 250 may communicate with an external device using wired/wireless communication technology.
  • the wireless communication technology is Bluetooth (bluetooth) communication, BLE (Bluetooth Low Energy) communication, near field communication (NFC), WLAN communication, Zigbee communication, infrared (Infrared Data Association, IrDA) communication, WFD (Wi-Fi Direct) communication, UWB (ultra-wideband) communication, Ant+ communication, WIFI communication, RFID (Radio Frequency Identification) communication, 3G communication, 4G communication, 5G communication, etc. may include, but this is only an example, and , but is not limited thereto.
  • the output unit 260 may output data input to the disease treatment apparatus 200 , stored data, processed data, and the like.
  • the output unit 260 is the electrical stimulation information applied to the user (eg, voltage level, current level, frequency, duration of each frequency, waveform), the environment measured by the first sensor unit 210
  • Information and biosignals measured by the second sensor unit 210 may be output by at least one of an auditory method, a visual method, and a tactile method.
  • the output unit 260 may include a display, a speaker, a vibrator, and the like.
  • FIG. 3 is a view showing an embodiment of an apparatus for treating bacterial and viral diseases using electrical stimulation according to an exemplary embodiment
  • FIG. 4 is a view showing a state in which the band of FIG. 3 is worn on the user's wrist
  • FIG. 5 is a view showing a state in which the band part of FIG. 3 is worn on the user's ankle
  • FIG. 6 is a rear view of the body part of FIG. 3 .
  • the disease treatment apparatus 300 may include a band unit 310 and a body unit 320 .
  • the band unit 310 may be formed in a wearable device type that is worn on the user's body and contacts the user's body, for example, a wrist watch type, a wrist band type, a ring type, a necklace type, an ankle band type, a thigh band type, a forearm band type, etc. can
  • the band unit 310 may be worn on the user's wrist (see FIG. 4 ) or on the user's ankle (see FIG. 5 ), but these are merely exemplary embodiments and are not limited thereto. .
  • the above-described electrode unit 110 , the first sensor unit 210 , and the second sensor unit 220 may be mounted on the band unit 310 .
  • the electrode unit 110 , the first sensor unit 210 , and the second sensor unit 220 may be disposed to be exposed toward the user's body from one side of the band unit 310 . Through this, when the user wears the band unit 310 , the electrode unit 110 , the first sensor unit 210 , and the second sensor unit 220 may naturally contact the user's body.
  • the band unit 310 may include an elastic material for easy wearing by a user.
  • the band unit 310 may include a length adjustment means 311 such as a button, a buckle, Velcro, etc. that can adjust the length in a state wrapped around the user's body.
  • the band unit 310 may include a separate cushioning material capable of performing a cushioning function so as to reduce skin irritation when worn.
  • the cushion material allows the user to wear the band unit 310 for a long time without discomfort.
  • the band unit 310 may include a display 312 .
  • the display 312 displays the electrical stimulation information (eg, voltage magnitude, current magnitude, frequency, duration of each frequency, waveform) transmitted to the user, environmental information measured by the first sensor unit 210 and the second sensor unit ( The biosignals measured in 210) may be displayed.
  • the electrical stimulation information eg, voltage magnitude, current magnitude, frequency, duration of each frequency, waveform
  • a battery for operation of the band unit 310 may be built in the inside of the band unit 310 .
  • the main body 320 may be equipped with the aforementioned electrical stimulation generating unit 120 , the control unit 130 , the input unit 230 , the storage unit 240 , the communication unit 250 , and the output unit 260 .
  • the body part 320 may be connected to the band part 310 through a wire L connected to the port P.
  • the electrical stimulation generated by the electrical stimulation generating unit 120 mounted on the body unit 320 is transmitted to the band unit 310 through the wire (L), and the electrical stimulation transmitted to the band unit 310 is transmitted to the band unit 310 . It may be applied to the user's body through the mounted electrode unit 110 .
  • a microcurrent may be transmitted to the user's body through electrical stimulation applied to the user's body.
  • the port (P) and the electric wire (L) may be configured to be detachable. Since the wire (L) is configured to be detachable from the port (P), there is an advantage of convenient storage and use.
  • An input unit 230 may be formed on one side of the main body 320 .
  • the input unit 230 may include at least one button for adjusting or receiving an electrical stimulation condition or operation condition of the disease treatment apparatus 300 such as the magnitude, frequency, duration of each frequency, and waveform.
  • the at least one button may include a power button capable of receiving a signal for turning on/off the main body 320 or the disease treatment apparatus 300 .
  • the at least one button may include another button for storing an electrical stimulation condition or an operating condition of the disease treatment apparatus 300 or using an additional function.
  • a clip 321 may be formed on the rear surface of the main body 320 .
  • the main body 320 may be easily worn on clothes or the like through the clip 321 .
  • a battery for the operation of the main body 320 may be built-in inside the main body 320 .
  • bacteria and viruses can be effectively killed, bacterial and viral diseases can be treated quickly and efficiently.
  • PBS phosphate buffer saline
  • the sample from each plate was harvested, diluted decimal in 0.45% saline, and the diluted sample was cultured overnight in TSA (tryptone soy media) medium. could get results.
  • TSA tryptone soy media
  • p-coronavirus (enterovirus) was used, and the virus titer was calculated by calculating 50% tissue culture infection (TCID50).
  • the above-described embodiments may be implemented as computer-readable codes on a computer-readable recording medium.
  • the computer-readable recording medium may include any type of recording device in which data readable by a computer system is stored. Examples of the computer-readable recording medium may include ROM, RAM, CD-ROM, magnetic tape, floppy disk, optical disk, and the like.
  • the computer-readable recording medium may be distributed in network-connected computer systems, and may be written and executed as computer-readable codes in a distributed manner.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Cardiology (AREA)
  • Physiology (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Optics & Photonics (AREA)
  • Pulmonology (AREA)
  • Electrotherapy Devices (AREA)

Abstract

Selon un mode de réalisation, un dispositif de traitement de maladies bactériennes et virales peut comprendre : une unité de génération de stimulations électriques qui génère successivement des stimulations électriques de fréquences différentes ; et une unité d'électrode qui est mise en contact avec un corps d'utilisateur attaqué par une maladie bactérienne ou virale en vue d'appliquer successivement les stimulations électriques générées de différentes fréquences au corps d'utilisateur.
PCT/KR2021/000822 2020-05-27 2021-01-21 Dispositif de traitement de maladies bactériennes et virales par stimulation électrique Ceased WO2021241838A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR10-2020-0063421 2020-05-27
KR20200063421 2020-05-27
KR1020210005928A KR20210146775A (ko) 2020-05-27 2021-01-15 전기자극을 이용한 세균 및 바이러스성 질병 치료 장치
KR10-2021-0005928 2021-01-15

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WO2021241838A1 true WO2021241838A1 (fr) 2021-12-02

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Application Number Title Priority Date Filing Date
PCT/KR2021/000822 Ceased WO2021241838A1 (fr) 2020-05-27 2021-01-21 Dispositif de traitement de maladies bactériennes et virales par stimulation électrique

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