WO2021053465A1

WO2021053465A1 - Noise reduction for pumps in therapy devices

Info

Publication number: WO2021053465A1
Application number: PCT/IB2020/058371
Authority: WO
Inventors: Christopher Brian Locke
Original assignee: KCI Licensing Inc
Current assignee: KCI Licensing Inc
Priority date: 2019-09-19
Filing date: 2020-09-09
Publication date: 2021-03-25
Anticipated expiration: 2022-03-19

Abstract

This disclosure describes devices, systems, and methods related to therapy devices and other devices including a pump and a speaker that is configured to substantially cancel at least a portion of the noise output by the pump. An illustrative wound therapy device includes a pump configured to be worn by a user and configured to output a first noise wave form. The wound therapy device includes a speaker disposed proximate to the pump. The wound therapy device further includes a controller coupled to the pump and to the speaker and configured to output a second noise waveform to substantially cancel at least a portion of the first noise waveform.

Description

NOISE REDUCTION FOR PUMPS IN THERAPY DEVICES

CROSS-REFERENCE TO REUATED APPUICATIONS

[0001] This application claims the benefit of priority to U.S. Provisional Application No. 62/902,579, filed on September 19, 2019, which is incorporated herein by reference in its entirety.

TECHNICAU FIEUD

[0002] Aspects of the present disclosure relate generally to wound therapy devices, and more specifically, but not by way of limitation, to wound therapy devices that provide pressurized wound therapy.

BACKGROUND

[0003] Some therapy devices provide therapeutic pressure to a wound site of a user. For example, these therapy devices can include a dressing coupled to the wound site and a pump that applies a therapeutic amount of positive or negative pressure to the wound site. Most such therapy devices are large bulky devices not designed for mobile or discreet use. Some mobile and discreet therapy devices are small enough to be discreetly worn by the user. Such discreet therapy devices may include small, rechargeable batteries to power the therapy device and enable use of the therapy device continuously throughout the day. However, while the therapy device can be made small enough to be discreetly and comfortably worn, the pumps of the therapy device generate some audible noise. Accordingly, while such therapy devices are discreet to the eye, such systems produce noise and are not discreet in terms of sound. As an example, diaphragm pumps generate an audible noise, e.g., an audible “hum” of low frequency noise.

[0004] Such audible noise can be distracting or embarrassing to a wearer of the therapy device. For example, the noise may draw attention to the wearer while out in public or may cause difficulties sleeping. Some types of pumps, such as piezoelectric pumps, may be significantly quieter. However, such pumps require a larger amount of power than diaphragm (or other) pumps, and thus consume battery power too quickly, thereby causing difficulties with supplying power using rechargeable batteries that are still small enough such that the overall device is still mobile and visually discreet. Some pumps are completely insulated by an insulating material (e.g., insulation) to reduce noise, but the insulation may make the device larger and bulkier, and may cause thermal issues for the device. The thermal issues (e.g., overheating) may cause the pump to fail and the battery to discharge and degrade more quickly. SUMMARY

[0005] This disclosure describes apparatus, systems, methods, and computer-readable storage devices for reducing at least a portion of the noise output by a device that includes a pump. Although described in the context of a wound therapy device, the techniques of the present disclosure can be applied to other devices, such as blood pressure monitors, infusion devices, wound drainage devices, or mattress inflation devices, as non-limiting examples. An illustrative wound therapy device may include a pump configured to apply pressure to the site of a wound. For example, the wound therapy device may be a negative-pressure wound therapy (nPWT) device, as a non-limiting example. While operating, the pump may emit a first noise waveform, at least some of which is audible to a wearer of the wound therapy device. The wound therapy device may also include a speaker and a controller coupled to the pump and to the speaker. The controller may be configured to cause the speaker to output a second noise waveform to substantially cancel at least a portion of the first noise waveform. For example, the speaker may outwardly emit (e.g., emit into the air surrounding the speaker, as opposed to outputting into a channel, like an ear canal) the second noise waveform into one or more directions. In some implementations, the speaker (such as a speaker array or speakers) may outwardly emit different second noise waveforms into different directions to cancel at least a portion of the first noise waveform (e.g., pump noise) and reflections thereof. Thus, pump noise in an area or environment may be reduced.

[0006] To substantially cancel the first noise waveform, the second noise waveform may have substantially the same frequency as the first noise waveform and may have an amplitude that is substantially inverted with respect to an amplitude of the first noise waveform. Because of the inverted amplitude, the second noise wave form may substantially cancel at least a portion of the first noise waveform, such that the noise produced by the pump is reduced (or eliminated). Thus, a noisier pump, such as a diaphragm pump, can be used in a discreet wound therapy device without causing disruption to the wearer’s day-to-day activities, thereby improving a quality of life of the wearer.

[0007] In some implementations, the wound therapy device includes an “active” noise cancellation system. For example, the wound therapy device may include a first microphone that is disposed near the pump and configured to capture the first noise waveform. The first microphone may provide first audio data relating to the first noise waveform to the controller, and the controller may adjust the second noise waveform based on the first audio data. For example, the controller may adjust the amplitude, the frequency, or both, of the second noise wave form to better match (and cancel) the first noise waveform. Additionally, if the first noise waveform changes, such as due to changes in a duty cycle of the pump, changes in the ambient temperature or pressure, changes in surroundings (e.g., reflections of the first noise waveforms), etc., the controller may adjust the second noise waveform to compensate for the changes. Additionally, in some implementations, the wound therapy device includes a second microphone disposed near the speaker such that the second microphone captures a combination of the first noise waveform and the second noise waveform. The second microphone transmits second audio data indicative of the combination to the controller, and the controller may be further configured to adjust the second noise waveform based on the second audio data. Using one (or two) microphone(s) to provide feedback to the controller enables the controller to more accurately generate the second noise waveform to substantially cancel at least a portion of the first noise waveform.

[0008] In some implementations, the wound therapy device includes a “passive” noise cancellation system. For example, the wound therapy device may not include microphones that cause the controller to adjust the second noise waveform. Instead, prior to being released to the market, the particular pump, a representative pump, or multiple pumps of different fabrication batches may be studied to determine an average noise waveform produced by the pump(s), and the controller may be programmed with the average noise waveform. Thus, the controller may cause the speaker to output the average noise waveform, which may substantially cancel at least a portion of the first noise waveform output by the particular pump of the wound therapy device. The passive noise cancellation system may not be as effective as the active noise cancellation system (e.g., due to differences in the first noise waveform output by a particular pump compared to the average noise waveform output by the speaker), but the passive noise cancellation system may be less complex, and thus, easier and cheaper to implement in a wound therapy device. Additionally, such passive noise cancellation systems may be smaller and consume less power because they do not utilize a microphone and active processing.

[0009] In some such passive implementations, the controller may be preprogrammed with multiple noise waveforms for different atmospheric pressure levels, and the wound therapy device may include an atmospheric pressure sensor configured to measure the ambient atmospheric pressure and to provide atmospheric pressure data to the controller. The controller may adjust the second noise waveform based on the atmospheric pressure data (e.g., by selecting a waveform that corresponds to the measured atmospheric pressure). Similar operations may be performed based on other environmental sensors. For example, multiple noise waveforms for different temperatures may be stored when a temperature sensor is included in the wound therapy device. As another example, multiple noise waveforms for different ambient sound levels may be stored when a microphone is included in the wound therapy device.

[0010] In some implementations, the wound therapy device may include both passive and active noise cancellation modes. In such implementations, the modes may be activated and/or switched based on user input, ambient sound level, battery level, or both. For example, at low battery levels the wound therapy device may switch from active to passive. As another example, a user may activate active noise cancellation based on hearing some pump noise or being in a quiet environment, such as a theater. Additionally or alternatively, the wound therapy device may activate sound cancellation (e.g., active or passive) based on an ambient sound level being less than a threshold. [0011] Some embodiments of the present wound therapy devices comprise: a pump configured to be worn by a user. The pump is further configured to output a first noise waveform. The wound therapy devices comprise a speaker disposed proximate to the pump. The wound therapy devices further comprise a controller coupled to the pump and to the speaker. The controller is configured to cause the speaker to output a second noise waveform to substantially cancel at least a portion of the first waveform.

[0012] In some of the foregoing embodiments of the present wound therapy devices, an amplitude of the second noise waveform is substantially inverted with respect to an amplitude of the first noise waveform. Additionally, or alternatively, a frequency of the second noise waveform is substantially the same as a frequency of the first noise waveform. In some of the foregoing embodiments of the present wound therapy devices, the wound therapy devices further comprise acoustic insulation coupled to the pump and positioned to direct the first noise waveform in a particular direction. In some such embodiments, the speaker is configured to emit the second noise waveform in the particular direction. Additionally, or alternatively, the wound therapy devices further comprise a metal core surrounding at least a portion of the pump, the metal core configured to reflect the first noise waveform in a particular direction. In some such embodiments, the speaker is configured to emit the second noise waveform in the particular direction. Additionally, or alternatively, the pump comprises a diaphragm pump. Additionally, or alternatively, the pump is configured to apply a negative pressure to a dressing.

[0013] In some of the foregoing embodiments of the present wound therapy devices, the wound therapy devices further comprise a first microphone disposed near the pump, the first microphone configured to capture the first noise waveform and to provide audio data relating to the first noise waveform to the controller. In some such embodiments, the controller is further configured to generate the second noise waveform based on the audio data received from the first microphone. In some such embodiments, the present wound therapy devices further comprise a second microphone configured to capture a combination of the first noise waveform and the second noise waveform and to provide second audio data relating to the combination to the controller. In some such embodiments, the controller is further configured to adjust the second noise waveform based on the second audio data received from the second microphone, generate a third noise waveform to substantially cancel reflections of the first noise waveform or the second noise waveform, or both. Additionally, or alternatively, the controller is further configured to adjust operation of the pump based on the audio data received from the first microphone.

[0014] In some of the foregoing embodiments of the present wound therapy devices, the wound therapy devices further comprise an atmospheric pressure sensor configured to measure an atmospheric pressure and to provide atmospheric pressure data to the controller. In some such embodiments, the controller is further configured to generate the second noise waveform based on the atmospheric pressure data. In some such embodiments, the controller comprises a memory configured to store noise waveform audio data corresponding to a plurality of different atmospheric pressures, and the controller is further configured to generate the second noise waveform based on a portion of the noise waveform audio data corresponding to the atmospheric pressure data.

[0015] In some of the foregoing embodiments of the present wound therapy devices, the controller is further configured to deactivate the speaker based on a battery level failing to satisfy a battery threshold or to switch to passive noise cancellation based on the battery level failing to satisfy the battery threshold. Additionally, or alternatively, the controller is further configured to deactivate the speaker based on a duty cycle of the pump failing to satisfy a duty cycle threshold.

[0016] Some embodiments of the present methods comprise: initiating output of a second noise waveform at a speaker of a wound therapy device to substantially cancel at least a portion of a first noise waveform output by a pump of the wound therapy device. The methods also comprise receiving audio data from a first microphone disposed near the pump, the audio data related to the first noise waveform. The methods further comprise adjusting the second noise waveform based on the audio data to continue substantially cancelling at least a portion of the first noise waveform.

[0017] In some of the foregoing embodiments of the present methods, adjusting the second noise waveform comprises adjusting an amplitude of the second noise waveform based on an amplitude of the first noise waveform determined from the first audio data. Additionally, or alternatively, adjusting the second noise waveform comprises adjusting a frequency of the second noise waveform based on a frequency of the first noise waveform determined from the first audio data. Additionally, or alternatively, the methods further comprise receiving second audio data from a second microphone configured to capture a combination of the first noise waveform and the second noise waveform and adjusting the adjusted second noise waveform based on the second audio data. In some such embodiments, further adjusting the adjusted second noise waveform comprises adjusting an amplitude of the adjusted second noise waveform, a frequency of the adjusted second noise waveform, or both. In some embodiments, the methods further comprise deactivating active noise cancellation or switching to passive noise cancellation based on determining that a battery level of a battery of the wound therapy device fails to satisfy a battery threshold.

[0018] Some embodiments of the present methods comprise: receiving first atmospheric pressure data indicating a first atmospheric pressure from an atmospheric pressure sensor of a wound therapy device. The methods comprise initiating output of a second noise waveform from a speaker of the wound therapy device to substantially cancel at least a portion of a first noise waveform output by a pump of the wound therapy device, the second noise waveform based on the first atmospheric pressure. The methods also comprise receiving second atmospheric pressure data indicating a second atmospheric pressure from the atmospheric pressure sensor, the second atmospheric pressure different from the first atmospheric pressure. The methods further comprise adjusting the second noise waveform based on the second atmospheric pressure. [0019] In some of the foregoing embodiments of the present methods, adjusting the second noise waveform comprises adjusting an amplitude of the second noise waveform based on the second atmospheric pressure. Additionally, or alternatively, adjusting the second noise waveform comprises adjusting a frequency of the second noise waveform based on the second atmospheric pressure. Additionally, or alternatively, one or more characteristics of the second noise waveform are selected based on the first atmospheric pressure. In some such embodiments, the one or more characteristics comprise an amplitude of the second noise waveform, a frequency of the second noise waveform, or both.

[0020] Some embodiments of present methods comprise: determining a battery level of a wound therapy device. The wound therapy device comprises a pump configured to output noise. The methods further comprise performing one of active noise cancellation or passive noise cancellation based on the battery level and a battery threshold. Performing the active noise cancellation or the passive noise cancellation comprises emitting, from one or more speakers, one or more noise waveforms in one or more directions to substantially cancel at least a portion of the noise.

[0021] In some of the foregoing embodiments, performing the active noise cancellation further comprises receiving first audio data from a microphone and generating the one or more noise waveforms based on the first audio data. The first audio data is related to the noise output by the pump. Additionally, or alternatively, performing the passive noise cancellation further comprises selecting one or more attributes of the one or more noise waveforms from noise waveform data stored at a memory. Additionally, or alternatively, the one or more speakers comprise a speaker array configured to output multiple noise waveforms in multiple directions.

[0022] Some embodiments of the present kits comprise: a wound therapy device configured to be worn by a user, the wound therapy device comprising a pump configured to output a first noise waveform. The wound therapy device also comprises a speaker disposed proximate to the pump. The wound therapy device also comprises a controller coupled to the pump and to the speaker, the controller configured to cause the speaker to output a second noise waveform to substantially cancel at least a portion of the first noise waveform. The kits further comprise a dressing configured to be coupled to a wound site and to the pump.

[0023] In some of the foregoing embodiments of the present kits, the kits further comprise a tube configured to couple the pump to the dressing. Additionally, or alternatively, the kits further comprise a battery configured to power the wound therapy device. Additionally, or alternatively, an adhesive configured to couple the dressing to a wound site of the user.

[0024] Some embodiments of the present apparatuses comprise: means for outputting audible noise. The audible noise corresponds to a first noise waveform. The apparatuses also include means for directing the audible noise into a particular direction and means for outputting a second noise waveform into an environment in the particular direction. The means for outputting the second noise waveform is disposed proximate to the means for outputting audible noise. The apparatuses also comprise means for controlling the means for outputting the second noise waveform to cause the means for outputting the second noise waveform to output the second noise waveform to substantially cancel at least a portion of the first noise waveform into the environment.

[0025] In some of the foregoing embodiments of the present apparatuses, the apparatuses comprise a blood pressure monitor. Additionally or alternatively, the apparatuses comprise an infusion device. Additionally, or alternatively, the apparatuses comprise a wound drainage device. Additionally, or alternatively, the apparatuses comprise a mattress inflation device.

[0026] As used herein, various terminology is for the purpose of describing particular implementations only and is not intended to be limiting of implementations. For example, as used herein, an ordinal term (e.g., “first,” “second,” “third,” etc.) used to modify an element, such as a structure, a component, an operation, etc., does not by itself indicate any priority or order of the element with respect to another element, but rather merely distinguishes the element from another element having a same name (but for use of the ordinal term). The term “coupled” is defined as connected, although not necessarily directly, and not necessarily mechanically. Additionally, two items that are “coupled” may be unitary with each other. To illustrate, components may be coupled by virtue of physical proximity, being integral to a single structure, or being formed from the same piece of material. Coupling may also include mechanical, thermal, electrical, communicational (e.g., wired or wireless), or chemical coupling (such as a chemical bond) in some contexts.

[0027] The terms “a” and “an” are defined as one or more unless this disclosure explicitly requires otherwise. The term “substantially” is defined as largely but not necessarily wholly what is specified (and includes what is specified; e.g., substantially 90 degrees includes 90 degrees and substantially parallel includes parallel), as understood by a person of ordinary skill in the art. As used herein, the term “approximately” may be substituted with “within 10 percent of’ what is specified. Additionally, the term “substantially” may be substituted with “within [a percentage] of’ what is specified, where the percentage includes .1, 1, or 5 percent; or may be understood to mean with a design, manufacture, or measurement tolerance. The phrase “and/or” means and or. To illustrate, A, B, and/or C includes: A alone, B alone, C alone, a combination of A and B, a combination of A and C, a combination of B and C, or a combination of A, B, and C. In other words, “and/or” operates as an inclusive or. Similarly, the phrase “A, B, C, or a combination thereof’ or “A, B, C, or any combination thereof’ includes: A alone, B alone, C alone, a combination of A and B, a combination of A and C, a combination of B and C, or a combination of A, B, and C.

[0028] The terms “comprise” (and any form of comprise, such as “comprises” and “comprising”), “have” (and any form of have, such as “has” and “having”), and “include” (and any form of include, such as “includes” and “including”). As a result, an apparatus that “comprises,” “has,” or “includes” one or more elements possesses those one or more elements, but is not limited to possessing only those one or more elements. Likewise, a method that “comprises,” “has,” or “includes” one or more steps possesses those one or more steps, but is not limited to possessing only those one or more steps.

[0029] Any aspect of any of the systems, methods, and article of manufacture can consist of or consist essentially of - rather than comprise/have/include - any of the described steps, elements, and/or features. Thus, in any of the claims, the term “consisting of’ or “consisting essentially of’ can be substituted for any of the open-ended linking verbs recited above, in order to change the scope of a given claim from what it would otherwise be using the open-ended linking verb. Additionally, it will be understood that the term “wherein” may be used interchangeably with “where.”

[0030] Further, a device or system that is configured in a certain way is configured in at least that way, but it can also be configured in other ways than those specifically described. The feature or features of one embodiment may be applied to other embodiments, even though not described or illustrated, unless expressly prohibited by this disclosure or the nature of the embodiments.

[0031] Some details associated with the aspects of the present disclosure are described above, and others are described below. Other implementations, advantages, and features of the present disclosure will become apparent after review of the entire application, including the following sections: Brief Description of the Drawings, Detailed Description, and the Claims.

BRIEF DESCRIPTION OF THE DRAWINGS

[0032] A further understanding of the nature and advantages of the present disclosure may be realized by reference to the following drawings. The following drawings illustrate by way of example and not limitation. For the sake of brevity and clarity, every feature of a given structure is not always labeled in every figure in which that structure appears. Identical reference numbers do not necessarily indicate an identical structure. Rather, the same reference number may be used to indicate a similar feature or a feature with similar functionality, as may non-identical reference numbers.

[0033] FIG. 1A is a diagram of an example of a therapy system for pressurized wound therapy;

[0034] FIG. IB is a diagram of an example of a tube taken along line A-A of FIG. 1A;

[0035] FIG. 2A is a diagram of an example of another system for wound therapy;

[0036] FIG. 2B is a cross-sectional view of an example of a tube taken along line B-B of FIG. 2A;

[0037] FIG. 3 is a diagram of an example of a device for reducing the noise output by a pump;

[0038] FIG. 4 is a diagram of an example of another device for reducing the noise output by a pump;

[0039] FIG. 5A is a diagram of an example of another device for reducing the noise output by a pump;

[0040] FIG. 5B is an image of an example of a prototype device for reducing the noise output by a pump; [0041] FIG. 6 is a flowchart illustrating an example of a method of operating a wound therapy device;

[0042] FIG. 7 is a flowchart illustrating an example of another method of operating a wound therapy device; and

[0043] FIG. 8 is a flowchart illustrating an example of another method of operating a wound therapy device.

DETAILED DESCRIPTION

[0044] As used herein, the terms “tissue site” and “target tissue” as used herein can broadly refer to a wound (e.g., open or closed), a tissue disorder, and/or the like located on or within tissue, such as, for example, bone tissue, adipose tissue, muscle tissue, neural tissue, dermal tissue, vascular tissue, connective tissue, cartilage, tendons, ligaments, and/or the like. The terms “tissue site” and “target tissue” as used herein can also refer to a surrounding tissue area(s) and/or areas of tissue that are not necessarily wounded or exhibit a disorder, but include tissue that would benefit from tissue generation and/or tissue that may be harvested and transplanted to another tissue location. The terms “tissue site” and “target tissue” may also include incisions, such as a surgical incision. In some implementations, “target tissue” may correspond or refer to a wound, and “tissue site” may correspond or refer to a tissue area(s) surrounding and including the target tissue. Additionally, the term “wound” as used herein can refer to a chronic, subacute, acute, traumatic, and/or dehisced incision, laceration, puncture, avulsion, and/or the like, a partial-thickness and/or full thickness bum, an ulcer (e.g., diabetic, pressure, venous, and/or the like), flap, and/or graft. A wound may include chronic, acute, traumatic, subacute, and dehisced wounds, partial-thickness bums, ulcers (such as diabetic, pressure, or venous insufficiency ulcers), flaps, grafts, and fistulas, for example.

[0045] The term “positive-pressure” (or “hyperbaric”) as used herein generally refers to a pressure greater than a local ambient pressure, such as the ambient pressure in a local environment external to a sealed therapeutic environment (e.g., an internal volume). In most cases, this positive-pressure will be greater than the atmospheric pressure at which the patient is located. Alternatively, the positive- pressure may be greater than a hydrostatic pressure associated with tissue at the tissue site. Unless otherwise indicated, values of pressure stated herein are gauge pressures. References to increases in positive-pressure typically refer to an increase in absolute pressure, and decreases in positive-pressure typically refer to a decrease in absolute pressure. Additionally, the process of increasing pressure may be described illustratively herein as “applying”, “delivering,” “distributing,” “generating”, or “providing” positive-pressure, for example.

[0046] The term “reduced-pressure” (and “negative-pressure” or “hypobaric”) as used herein generally refers to a pressure less than a local ambient pressure, such as the ambient pressure in a local environment external to a sealed therapeutic environment (e.g., an internal volume). In most cases, this reduced-pressure will be less than the atmospheric pressure at which the patient is located. Alternatively, the reduced-pressure may be less than a hydrostatic pressure associated with tissue at the tissue site. Unless otherwise indicated, values of pressure stated herein are gauge pressures. References to increases in reduced-pressure typically refer to a decrease in absolute pressure, and decreases in reduced-pressure typically refer to an increase in absolute pressure. Additionally, the process of reducing pressure may be described illustratively herein as “applying”, “delivering,” “distributing,” “generating”, or “providing” reduced-pressure, for example.

[0047] The term “fluid” may refer to liquid, gas, air, or a combination thereof. The term “fluid seal,” or “seal,” means a seal adequate to maintain a pressure differential (e.g., positive-pressure or reduced-pressure) at a desired site given the particular pressure source or subsystem involved. Similarly, it may be convenient to describe certain features in terms of fluid “inlet” or “outlet” in such a frame of reference. However, the fluid path may also be reversed in some applications, such as by substituting a reduced-pressure source (negative or hypobaric pressure source) for a positive-pressure source, and this descriptive convention should not be construed as a limiting convention.

[0048] FIG. 1A shows a perspective view of an illustrative system 100 (e.g., a therapy system) for providing wound therapy. System 100 may include a therapy device 110, a tube 114, and a dressing 116. System 100 is configured to provide therapy (e.g., oxygen therapy, positive-pressure therapy, negative-pressure therapy, or a combination thereof) at a tissue site 120 associated with a target area of a patient. For example, dressing 116 may be in fluid communication with tissue site 120 and may be in fluid communication with therapy device 110 via tube 114. In some implementations, system 100 may include one or more components commercially available through and/or from KCI USA, Inc. of San Antonio, Tex., U.S.A., and/or its subsidiary and related companies (collectively, “KCI”). In some implementations, system 100 is a disposable and/or discreet therapy system. For example, the therapy system is sized to fit underneath clothing and/or to attach to clothing of a person. An illustrative, non limiting example of commercially available discreet therapy systems include a “V.A.C. VIA”™ Therapy System available from Kinetic Concepts, Inc. (KCI) of San Antonio, Tex.

[0049] Therapy device 110 (e.g., a treatment apparatus) is configured to provide therapy to tissue site 120 via tube 114 and dressing 116. For example, therapy device 110 may include a pressure source (e.g., a negative-pressure source, such as a pump, or a positive-pressure source, such as a pressurized oxygen container, an oxygen concentrator, or an oxygen collector) configured to be actuatable (and/or actuated) to apply pressure differential relative to ambient conditions to dressing 116. As illustrative, non-limiting examples, positive-pressure applied to a tissue site may typically ranges between 5 millimeters mercury (mm Hg) (667 pascals (Pa)) and 30 mm Hg (4.00 kilo (k) Pa). Common therapeutic ranges are between 10 mm Hg (1.33 kPa) and 25 mm Hg (3.33 kPa). As illustrative, non-limiting examples, reduced-pressure applied to a tissue site may typically ranges between -5 millimeters mercury (mm Hg) (-667 pascals (Pa)) and -500 mm Hg (-66.7 kilo (k) Pa). Common therapeutic ranges are between -75 mm Hg (-9.9 kPa) and -300 mm Hg (-39.9 kPa).

[0050] In some implementations, as described further with reference to FIG. 2A, the therapy device 110 includes a reduced-pressure source, such as a vacuum source (e.g., a pump and/or the like), configured to be actuatable (and/or actuated) to apply reduced-pressure (e.g., negative pressure) to dressing 116. For example, therapy device 110 may include pump 150. In some implementations, therapy device 110 may alternate between providing positive-pressure therapy and negative-pressure therapy to the dressing 116, may provide positive-pressure therapy to a first portion of the dressing 116 and negative -pressure therapy to a second portion of the dressing 116, may provide no positive or negative pressure, or a combination thereof. In some such implementations, the therapy device 110 can provide positive-pressure therapy and negative-pressure therapy to the dressing 116 at the same time (e.g., partially concurrently). In some implementations, a speaker 152 is disposed proximate to pump 150 and configured to output a noise waveform to substantially cancel a noise waveform output by pump 150, as further described herein.

[0051] In some implementations, therapy device 110 includes a canister to receive fluid from tissue site 120 or to provide fluid to tissue site 120. In some implementations, the canister is internal to and/or integrated with therapy device 110. In other implementations, the canister is external to therapy device 110

[0052] Therapy device 110 may also include one or more other components, such as a sensor, a processing unit/controller 154 (e.g., a processor), an alarm indicator, a memory, a database, software, a display device, a user interface, a regulator, and/or another component, that further facilitate positive- pressure therapy or negative-pressure therapy. Additionally, or alternatively, therapy device 110 may be configured to receive fluid, exudate, and or the like via dressing 116 and tube 114. Therapy device 110 may include one or more connectors, such as a representative connector 138. Connector 130 is configured to be coupled to tube 114. Additionally, or alternatively, therapy device 110 may include one or more sensors, such a pressure sensor (e.g., a pressure transducer). The one or more sensors may be configured to enable therapy device 110 to monitor and/or sense a pressure associated with tube 114 and/or dressing 116. An illustrative example of therapy device 110 is described further herein at least with reference to FIG. 2A.

[0053] Tube 114 includes one or more lumens (e.g., one or more through conduits), such as a single lumen conduit or multiple single-lumen conduits. Tube 114 (e.g., a least one of the one or more lumens) is configured to enable fluid communication between therapy device 110 and dressing 116. For example, fluid(s) and/or exudate can be communicated between therapy device 110 and dressing 116, and/or one or more pressure differentials (e.g., positive-pressure, negative pressure, or both) can be applied by therapy device 110 to dressing 116. As an illustrative, non-limiting illustration, tube 114 is configured to deliver at least pressurized oxygen from therapy device 110 to dressing 116 to establish positive-pressure. Communication of fluid(s) and application of a pressure differential can occur separately and/or concurrently.

[0054] In some implementations, tube 114 may include multiple lumens, such as a primary lumen (e.g., a negative-pressure/fluid lumen) for application of negative-pressure and/or communication of fluid, and one or more secondary lumens proximate to or around the primary lumen. The one or more secondary lumens (e.g., one or more ancillary/peripheral lumens) may be coupled to one or more sensors (of therapy device 110), coupled to one or more valves, as an illustrative, non-limiting example. Although tube 114 is described as a single tube, in other implementations, system 100 may include multiple tubes, such as multiple distinct tubes coupled to therapy device 110, dressing 116, or both. [0055] As used herein, a “tube” broadly refers to a tube, pipe, hose, conduit, or other structure with one or more lumens adapted to convey fluid, exudate, and/or the like, between two ends. In some implementations, a tube may be an elongated, cylindrical structure with some flexibility; however, a tube is not limited to such a structure. Accordingly, tube may be understood to include multiple geometries and rigidity. Tube 114 includes one or more lumens (e.g., one or more through conduits), such as a single lumen conduit or multiple single-lumen conduits. Tube 114 (e.g., a least one of the one or more lumens) is configured to enable fluid communication between therapy device 110 and dressing 116. For example, fluid(s) and/or exudate can be communicated between therapy device 110 and dressing 116, and/or one or more pressure differentials (e.g., positive-pressure, negative pressure, or both) can be applied by therapy device 110 to dressing 116. As an illustrative, non-limiting illustration, tube 114 is configured to deliver at least pressurized oxygen from therapy device 110 to dressing 116 to establish negative-pressure. Communication of fluid(s) and application of a pressure differential can occur separately and/or concurrently.

[0056] Referring to FIG. IB, an illustrative example of a cross-section of tube 114 (in which tube 114 comprises a single lumen) along line A-A of FIG. 1A is shown. Tube 114 may include a primary lumen 121 (e.g., a negative-pressure/fluid lumen). In other implementations, tube 114 may include one or more secondary lumens, such as a positive-pressure/fluid lumen, one or more sense lumens, etc., or a combination thereof, such as described with reference to at least FIG. 2B. Although tube 114 has been described and/or shown as having a circular cross-sectional shape, in other implementations, tube 114 may have a cross-sectional shape other than a circle, such as an oval, triangle, quadrilateral, pentagon, star, or another shape, as illustrative, non-limiting examples.

[0057] Referring to FIG. 1A, dressing 116 includes a connector 130 (also referred to as a dressing connection pad or a pad), a drape 132, and a manifold 134 (also referred to as a distribution manifold or an insert). Drape 132 may be coupled to connector 130. To illustrate, drape 132 may be coupled to connector 130 via an adhesive, a separate adhesive drape over at least a portion of connector 130 and at least a portion of drape 132, or a combination thereof, as illustrative, non-limiting examples. [0058] Drape 132 may be configured to couple dressing 116 at tissue site 120 and/or to provide a seal to create an enclosed space (e.g., an interior volume) corresponding to tissue site 120. For example, drape 132 may be configured to provide a fluid seal between two components and/or two environments, such as between a sealed therapeutic environment and a local ambient environment. To illustrate, when coupled to tissue site 120, drape 132 is configured to maintain a pressure differential (provided by a positive-pressure source or a negative-pressure source) at tissue site 120. Drape 132 may include a drape aperture that extends through drape 132 to enable fluid communication between device and target tissue. Drape 132may be configured to be coupled to tissue site 120 via an adhesive, such as a medically acceptable, pressure-sensitive adhesive that extends about a periphery, a portion, or an entirety of drape 132. Additionally, or alternatively, drape 132 may be coupled to tissue site 120 via a double-sided drape tape, paste, hydrocolloid, hydrogel, and/or other sealing device or element, as illustrative, non limiting examples.

[0059] Drape 132 may include an impermeable or semi-permeable, elastomeric material, as an illustrative, non-limiting example. In some implementations, drape 132 may be liquid/gas (e.g., moisture/vapor) impermeable or semi -permeable. Examples of elastomers may include, but are not limited to, natural rubbers, polyisoprene, styrene butadiene rubber, chloroprene rubber, polybutadiene, nitrile rubber, butyl rubber, ethylene propylene rubber, ethylene propylene diene monomer, chlorosulfonated polyethylene, polysulfide rubber, polyurethane (PU), EVA film, co-polyester, and silicones. In some implementations, drape 132 may include the “V.A.C.® Drape” commercially available from KCI. Additional, specific non-limiting examples of materials of drape 132 may include a silicone drape, 3M Tegaderm® drape, and a polyurethane (PU) drape such as one available from Avery Dennison Corporation of Pasadena, Calif. An additional, specific non-limiting example of a material of the drape 132 may include a 30 micrometers (pm) matt polyurethane film such as the Inspire™ 2317 manufactured by Exopack™ Advanced Coatings of Matthews, N.C.

[0060] Manifold 134 is configured to be positioned on and/or near tissue site 120, and may be secured at the tissue site 120, such as secured by drape 132. The term “manifold” as used herein generally refers to a substance or structure that may be provided to assist in applying a pressure differential (e.g., negative-pressure differential) to, delivering fluids to, or removing fluids and/or exudate from a tissue site and/or target tissue. The manifold typically includes a plurality of flow channels or pathways that distribute fluids provided to and removed from the tissue site. In an illustrative implementation, the flow channels or pathways are interconnected to improve distribution of fluids provided to or removed from the tissue site. Manifold 134 may be a biocompatible material that may be capable of being placed in contact with the tissue site and distributing positive and/or negative-pressure to the tissue site. Manifold 134 may include, without limitation, devices that have structural elements arranged to form flow channels, such as foam, cellular foam, open-cell foam, porous tissue collections, liquids, gels, and/or a foam that includes, or cures to include, flow channels, as illustrative, non-limiting examples. Additionally, or alternatively, manifold may include polyethylene, a polyolefin, a polyether, polyurethane, a co-polyester, a copolymer thereof, a combination thereof, or a blend thereof.

[0061] In some implementations, manifold 134 is porous and may be made from foam, gauze, felted mat, or other material suited to a particular biological application. In a particular implementation, manifold 134 may be a porous foam and may include a plurality of interconnected cells or pores that act as flow channels. The foam (e.g., foam material) may be either hydrophobic or hydrophilic. As an illustrative, non-limiting example, the porous foam may be a polyurethane, open-cell, reticulated foam such as GranuFoam® material manufactured by Kinetic Concepts, Incorporated of San Antonio, Tex. [0062] In some implementations, manifold 134 is also used to distribute fluids such as medications, antibacterials, growth factors, and other solutions to the tissue site. Other layers may be included in or on manifold 134, such as absorptive materials, wicking materials, hydrophobic materials, and hydrophilic materials. In an implementation in which the manifold 134 includes a hydrophilic material, manifold 134 may be configured to wick fluid away from tissue site 120 and to distribute negative pressure and/or positive-pressure to tissue site 120. The wicking properties of manifold 134 may draw fluid away from the tissue site 120 by capillary flow or other wicking mechanisms. An illustrative, non-limiting example of a hydrophilic foam is a polyvinyl alcohol, open-cell foam such as V.A.C. WhiteFoam® dressing available from Kinetic Concepts, Inc. of San Antonio, Tex. Other hydrophilic foams may include those made from polyether and/or foams that have been treated or coated to provide hydrophilicity.

[0063] In some implementations, manifold 134 is constructed from bioresorbable materials that do not have to be removed from tissue site 120 following use of the system 100. Suitable bioresorbable materials may include, without limitation, a polymeric blend of polylactic acid (PLA) and polyglycolic acid (PGA). The polymeric blend may also include without limitation polycarbonates, polyfumarates, and capralactones. Manifold 134 may further serve as a scaffold for new cell-growth, or a scaffold material may be used in conjunction with manifold 134 to promote cell-growth. A scaffold may be a substance or structure used to enhance or promote the growth of cells or formation of tissue, such as a three-dimensional porous structure that provides a template for cell growth. Illustrative examples of scaffold materials include calcium phosphate, collagen, PLA/PGA, coral hydroxy apatites, carbonates, or processed allograft materials. Although a manifold 134 is illustrated in FIG. 1A, in other implementations, dressing 116 does not include manifold 134. In such implementations, drape 132 of dressing 116 is coupled to connector 130.

[0064] Connector 130 includes a body 142 (e.g., a housing) and a base 144, and is configured to be coupled to tube 114 via an interface 146 (e.g., a port). Base 144 is configured to be coupled to dressing 116. For example, base 144 may be coupled, such as via an adhesive, to drape 132 and/or manifold 134. In some implementations, base 144 comprises a flange that is coupled to an end of body 142 and/or is integrally formed with body 142. Connector 130, such as body 142, base 144, interface 146, or a combination thereof, may be made of rigid material and/or a semi-rigid material. In a non-limiting example, connector 130 may be made from a plasticized polyvinyl chloride (PVC), polyurethane, cyclic olefin copolymer elastomer, thermoplastic elastomer, poly acrylic, silicone polymer, or polyether block amide copolymer. In some implementations, connector 130 is formed of a semi-rigid material that is configured to expand when under a force, such as positive-pressure greater than or equal to a particular amount of pressure. Additionally or alternatively, connector 130 may be formed of a semi-rigid material that is configured to collapse when under a force, such as reduced-pressure less than or equal to a threshold pressure.

[0065] Body 142 includes one or more channels or one or more conduits that extend from and/or are coupled to interface 146. To illustrate, body 142 may include a primary channel configured to be coupled in fluid communication with a primary lumen (e.g., 121) of tube 114. The primary channel may be coupled to a cavity (e.g., a tissue cavity partially defined by body 142) having an aperture open towards manifold 134 (and/or towards tissue site 120). For example, the primary channel may include a first opening associated with interface 146 and a second opening (distinct from the aperture of the cavity) associated with the cavity. Thus, the primary channel may define a through channel of body 142 to enable fluid communication between interface 146 and tissue site 120.

[0066] Body 142 includes a channel (e.g., a through channel) having a first aperture open opposite dressing 116 and a second aperture open towards dressing 116. For example, the first aperture is located on an outer surface side (e.g., an ambient environment surface) of connector 130 and the second aperture is located on an inner surface side (e.g., a tissue facing side) of connector 130. The second aperture is configured to be coupled to one or more lumens of tube 114, such as coupled via the cavity. Illustrative, non-limiting examples of commercially available connectors include a “V.A.C. T.R.A.C.® Pad,” or “Sensa T.R.A.C.® Pad” available from Kinetic Concepts, Inc. (KCI) of San Antonio, Tex.

[0067] During operation of system 100, dressing 116 is coupled to tissue site 120 over a wound. Additionally, dressing 116 is coupled to therapy device 110 via tube 114. Negative-pressure or positive- pressure can be applied to dressing 116 (e.g., an interior volume of dressing 116) by pump 150 (e.g., a pressure source). In some implementations, pump 150 is a diaphragm pump or other type of pump that outputs a sound that is audible to a human, such as a “hum.” Pump 150 may be configured to be worn by a user. For example, pump 150 (or therapy device 110) may be light enough to be attached to a person with adhesive. Additionally, pump 150 (or therapy device 110) may be configured to maintain a temperature that is low enough to avoid causing bums to the user. Additionally, pump 150 (or therapy device 110) may be small enough to be discreetly worn underneath clothing. In some implementations, therapy device 110 is a single use, disposable device.

[0068] Controller 154 may operate pump 150 to apply negative -pressure (and/or positive-pressure) to dressing 116. During operation of pump 150, pump 150 may emit a first noise waveform (e.g., noise) that is audible to the human ear. Controller 154 may also cause speaker 152 to output a second noise waveform to substantially cancel at least a portion of the first noise waveform, thereby reducing the noise detectable to the human ear. For example, controller 154 may configure speaker 152 to output the second noise waveform having substantially the same frequency as the first noise waveform emitted by the pump. However, the amplitude of the second noise waveform may be substantially inverted with respect to the amplitude of the first noise waveform. This inversion of amplitudes may cause the second noise waveform to substantially cancel at least a portion of the first noise waveform. The portion may be selected as a portion within a frequency range that is audible to humans. Thus, emitting the second noise waveform from speaker 152 may reduce the overall noise experienced by a user of therapy device 110 and by people proximate to the therapy device 110.

[0069] In some implementations, system 100 may have a designed noise cancellation threshold or thresholds. For example, in some implementations system 100 may have a designed maximum decibel (dB) level for safety and/or comfort. To illustrate, a threshold of 30 dB may be used for safety and/or comfort, and system 100 may cancel noise such that the perceived noise of the pump, i.e., a reduced or canceled signal (e.g., 324), is below 30 dB. As another example, system 100 may have a designed maximum decibel (dB) level for background noise. To illustrate, a threshold of 20 dB may be used for background noise, system 100 may cancel noise such that the perceived noise of the pump, i.e., a reduced or canceled signal (e.g., 324), is below 20 dB. A particular threshold of the thresholds may be activated or selected based on user input and/or sensor data. Such thresholds may also be used to determine when to activate noise cancellation and/or what noise type of noise cancellation to activate. For example, when environmental noise is above 30 dB (or 20 dB) no noise cancellation may be performed or passive (or active) noise cancellation may be performed.

[0070] Different devices (e.g., pumps) may have different frequency ranges where noise cancellation is useful, or preferred. Thus, system 100 may be designed to cancel noise within a wide range of frequencies and/or for frequencies that are generated by the device (and their harmonics). For example, system 100 may be designed to cancel noise in the range from 1 kHz to 6 kHz in some implementations. In other implementations, other ranges may be used, such as 250 Hz to 8kHz or any subrange therebetween. Additionally, or alternatively, system 100 may be designed to cancel noise within a smaller range or for a particular product/pump. As an illustrative, non-limiting example, for a Prevena 125 system/pump, the noise cancellation may be for noise of frequencies of 400 Hz to 6 kHz, and harmonics thereof.

[0071] Thus, the system 100 reduces the noise emitted by therapy device 110 (e.g., by pump 150). Reducing the noise emitted by therapy device 110 can make therapy device 110 more discreet and improve the quality of life of a wearer. For example, the noise level may not be sufficiently audible to draw attention to the wearer when the wearer is out in public, performing everyday activities. Additionally, the noise level may be not be sufficiently audible such that the wearer’s sleep is not disrupted. Thus, reducing the noise emitted by pump 150 is advantageous.

[0072] Referring to FIG. 2A, an illustrative example of an illustrative system 200 (e.g., a negative- pressure therapy system) is shown. System 200 includes a negative-pressure therapy device 210 (e.g., a negative-pressure therapy apparatus), a tube 214, and a dressing 216. Dressing 216 is coupled to device 210 via tube 214. Device 210 and dressing 216 may include or correspond to therapy device 110 and dressing 116, respectively. Tube 214 may include or correspond to tube 114.

[0073] Referring to FIG. 2B, an illustrative example of a cross-section of tube 214 (when tube 114 comprises multiple lumens) along line B-B of FIG. 2A is shown. Tube 214 may include a primary lumen 221 (e.g., a negative-pressure/fluid lumen) and one or more secondary lumens, such as a first secondary lumen 222 (e.g., a positive-pressure/fluid lumen), a second secondary lumen 224 (e.g., a first sense lumen), a third secondary lumen 226 (e.g., a second sense lumen), and a fourth secondary lumen 228 (e.g., a third sense lumen). Although described as having a single primary lumen (e.g., 221), tube 214 may have multiple primary lumens, such as a first primary lumen for negative-pressure and a second primary lumen for positive-pressure. Additionally, or alternatively, primary lumen 221 may be configured to for both positive-pressure and negative-pressure. Although described as having four secondary lumens, in other implementations, tube 214 may include fewer than or more than four secondary lumens. Although tube 214 has been described and/or shown as having a circular cross- sectional shape, in other implementations, tube 214 may have a cross-sectional shape other than a circle, such as an oval, triangle, quadrilateral, pentagon, star, or another shape, as illustrative, non-limiting examples. In an alternative implementation, primary lumen 221 may be a positive-pressure/fluid lumen, first secondary lumen 222 may be a negative-pressure/fluid lumen), and secondary lumens 224, 226, 228 may be sense lumens.

[0074] Dressing 216 is configured to be coupled to (e.g., adhered to) a tissue site 220 of a patient. Tissue site 220 may include or correspond to tissue site 120. Dressing 216 may include one or more components, such as a connector 230, a drape 232, a manifold 234, or a combination thereof, as illustrative, non-limiting examples. Connector 230 may include or correspond to connector 130. Drape 232 and manifold 234 may include or correspond to drape 132 and manifold 134, respectively. Drape 232 may be coupled to connector 230 and/or manifold 234, and may include an opening 235 (e.g., a drape aperture) to enable communication (e.g., fluid communication) between connector 230 and manifold 234.

[0075] As shown, drape 232 is coupled to tissue site 220 via a representative adhesive 237, such as a medically acceptable, pressure-sensitive adhesive that extends about a periphery, a portion, or an entirety of drape 232. Additionally, or alternatively, drape 232 may be coupled to tissue site 220 via a double-sided drape tape, paste, hydrocolloid, hydrogel, and/or other sealing device or element, as illustrative, non-limiting examples. Drape 232 is configured to be coupled to tissue site 220 such that drape 232 covers manifold 234 (and target tissue 236) to form and/or define an interior volume 238 between drape 232 and tissue site 220 (e.g., target tissue 236). To illustrate, interior volume 238 may correspond to a sealed therapeutic environment. For example, the tissue proximate the target tissue 236 may be undamaged epidermis peripheral to target tissue 236. The sealed therapeutic environment may be isolated from an external environment, such as an external environment at ambient pressure.

[0076] As shown, manifold 234 is positioned within interior volume 238 at (e.g., on or above) target tissue 236 of tissue site 220. In some implementations, manifold 234 may contact tissue site 220, target tissue 236, or both. In some implementations, such as when target tissue 236 extends into tissue from a tissue surface 219 creating a cavity, manifold 234 may partially or completely fill the cavity. In other implementations, manifold 234 may be placed over target tissue 236. Manifold 234 may take one or more forms, and/or may have one or more configurations (e.g., sizes, shapes, and/or thicknesses), depending on one or more factors, such as the type of treatment being implemented, the nature and size of target tissue 236, a stage of treatment, or a combination thereof. For example, the size and shape of the manifold 234 may be adapted to target tissue 236 and/or tissue site 220. To illustrate, manifold 234 may be adapted to contours of target tissue 236 and/or tissue site 220. In a particular implementation, manifold 234 includes a foam, such as GranuFoam® material manufactured by Kinetic Concepts, Incorporated of San Antonio, TX, as an illustrative, non-limiting example.

[0077] Connector 230 may include a connector body 242, a base 244, and an interface 246 (e.g., a port). Connector body 242 (e.g., a housing) may include or correspond to body 142. Base 244 may include or correspond to base 144. Interface 246 may include or correspond to interface 146. Interface 246 is configured to be coupled to tube 214.

[0078] Further, connector body 242 may include one or more channels or conduits that extend from and/or are coupled to interface 246. For example, connector body 242 may include a conduit and a secondary channel (e.g., a reduced-pressure or exudate channel) that are in fluid communication with interior volume 238. To illustrate, the secondary channel may have an aperture defined by base 244, and which is positioned over manifold 234, to enable fluids and/or exudate to be drawn from target tissue 236. In some implementations, connector 230 may be positioned on manifold 234 such that a perimeter of the aperture (defined by base 244) is in direct contact with manifold 234. When the conduit and the second channel are in fluid communication with interior volume 238, connector 230 may operate to maintain fluid communication between interior volume 238 and device 210 via tube 214, and to prevent fluid communication between interior volume (e.g., a sealed therapeutic environment formed by dressing 216) and the ambient environment.

[0079] Tube 214 includes one or more lumens. For example, tube 214 may include a negative - pressure/fluid lumen (e.g., 221), a positive-pressure/fluid lumen, and one or more sense lumens. As shown, a first end of tube 214 is coupled to dressing 216 and a second end of tube 214 is coupled to device 210. In some implementations, the second end of tube 214 may include a therapy device connector configured to couple (e.g., mate) with device 210.

[0080] Device 210 includes a controller 260, one or more interfaces 262, one or more I/O devices 264, and one or more connectors, such as a representative connector 266. Controller 260 may include or correspond to controller 154. Device 210 further includes one or more conduits 268, a fluid chamber 270, pressure sensors 272, 274, one or more valves 276 (e.g., solenoid valves), a reduced-pressure source 278, a speaker 288, and optionally one or more microphones 289 and/or an atmospheric pressure sensor 287. Reduced-pressure source 278 may include or correspond to pump 150, and speaker 288 may include or correspond to speaker 152.

[0081] Connector 266, such as connector 138, is configured to be coupled to tube 214, such as the second end of tube 214. Connector 266 includes one or more ports/interfaces, such as a first port/interface 280, a second port/interface 282, a third port/interface 284, a fourth port/interface 286. When connector 266 is coupled to tube 214, the negative-pressure/fluid lumen (e.g., 221) is in fluid communication with first port/interface 280, the positive-pressure/fluid lumen (e.g., 222) is in fluid communication with second port/interface 282, first sense lumen (e.g., 224) is in fluid communication with third port/interface 284, and second sense lumen (e.g., 226) is in fluid communication with fourth port/interface 286.

[0082] Each of first port/interface 280, second port/interface 282, third port/interface 284, and fourth port/interface 286 is coupled to one or more components of device 210 via one or more conduits (e.g., 268). For example, first port/interface 280 is coupled to reduced-pressure source 278, second port/interface 282 is coupled through fluid chamber 270 (e.g., a canister or a liquid-collection cavity) to positive-pressure source 279, third port/interface 284 is coupled to a first pressure sensor 272, and fourth port/interface 286 is coupled to a second pressure sensor 274. The pressure sensors 272, 274 may be configured to generate data indicative of pressure within dressing 216. Although described as having two pressure sensors (e.g., 272, 274), in other implementations, device 210 may include fewer than two pressure sensors, such as no pressure sensors or a single pressure sensor, or more than two pressure sensors. Additionally, each of first port/interface 280, second port/interface 282, third port/interface 284, and fourth port/interface 286 is coupled to a corresponding valve (e.g., 276), such as a solenoid valve, which is configured to change pressure from dressing 216. First port/interface 280 is coupled to reduced-pressure source 278 and a corresponding valve 276 via a conduit 268.

[0083] Reduced-pressure source 278 is configured to provide reduced or negative-pressure to interior volume 238 of dressing 216 such that interior volume 238 is reduced, and/or negative-pressure is applied to at least target tissue 236. Reduced-pressure source 278 may include a mechanically and/or electrically-powered device, such as a manually-actuated or manually-charged pump, a vacuum pump, an electrically-driven vacuum pump, a suction pump, a wall suction port, a micro-pump, a disc-pump, and/or the like, as illustrative, non-limiting examples. As illustrated in FIG. 2A, the reduced-pressure source 278 and the positive-pressure source 279 may operate in conjunction with each other and are applied to different portions of tissue site 220 via different lumens (e.g., 221, 222) of tube 214. In other implementations, the reduced-pressure source 278 and the positive-pressure source 279 share a lumen (e.g., 221 or 222) of tube 214 and the positive-pressure source 279 operates in the alternative to the reduced-pressure source 278 (e.g., operate in distinct cycles). For example, the positive-pressure source 279 operates before or after the reduced-pressure source 278 to remove exudate from tissue site 220. In some implementations, reduced-pressure source 278 includes a diaphragm pump or other type of pump that is audible to the human ear.

[0084] In some implementations, device 210 further includes positive-pressure source 279 that is configured to provide positive-pressure to interior volume 238 of dressing 216 such that interior volume 238 is expanded, and/or positive-pressure is applied to at least target tissue 236. Positive-pressure source 279 may include a mechanically and/or electrically-powered device, such as a manually-actuated or manually-charged pump, an oxygen tank, an oxygen collector, a wall port, a micro-pump, a disc- pump, and/or the like, as illustrative, non-limiting examples.

[0085] Reduced-pressure source 278 (and positive-pressure source 279) may emit noise when operated to apply pressure to dressing 216. This noise may be characterized as a first noise waveform. Speaker 288 may be configured to output a second noise waveform to substantially cancel at least a portion of the first noise waveform, as further described herein. In some implementations, speaker 288 may include multiple speakers and/or a speaker array configured to emit multiple noise waveforms in multiple directions. One or more microphones 289 may be configured to capture the noise waveforms (e.g., the first noise waveform or a combination of the first noise waveform and the second noise waveform) and to provide audio data to controller 260 to use in adjusting the second noise waveform, as further described herein. Atmospheric pressure sensor 287 may be configured to measure the ambient atmospheric pressure and provide atmospheric pressure data to controller 260 for use in adjusting the second noise waveform, as further described herein.

[0086] Controller 260 includes a processor 290 coupled to a memory 292 (e.g., a computer-readable storage device). Memory 292, such as a non-transitory computer-readable storage medium, may include volatile memory devices (e.g., random access memory (RAM) devices), nonvolatile memory devices (e.g., read-only memory (ROM) devices, programmable read-only memory, and flash memory), or both. Memory 292 may be configured to store instructions 293, a pressure profile 294, noise waveform data 295, and optionally first audio data 296, second audio data 297, and atmospheric pressure data 298. Instructions 293 may be configured to, when executed by the one or more processors 290, cause the processor(s) 290 to perform one or more operations.

[0087] Pressure profile 294 may include desired target pressures to be provided to a patient over a time period. In some implementations, the pressure profile 294 may include a set-up profile applying target pressures at the commencement of therapy treatments and a maintenance profile for applying target pressure during therapy. Noise waveform data 295 may include information related to the second noise waveform emitted by speaker 288. For example, in some implementations, noise waveform data 295 indicates parameter values (e.g., amplitude, frequency, etc.) of noise waveforms that have been emitted by speaker 288 for tracking trends and changes and anticipating adjustments. In other implementations, noise waveform data 295 includes a single set or multiple sets of parameters for noise waveforms to be selected based on particular data, as further described herein.

[0088] Processor 290 may include a microcontroller/microprocessor, a central processing unit (CPU), a field-programmable gate array (FPGA) device, an application-specific integrated circuits (ASIC), another hardware device, a firmware device, or any combination thereof. Processor 290 may be configured to execute instructions 293 to perform the operations described herein and/or operate according to pressure profile 294. Processor 290 may also be configured to process data, such as first audio data 296, second audio data 297, and atmospheric pressure data 298.

[0089] The one or more interfaces 262 may include a wired interface, a wireless interface, or both. In some implementation, the one or more interfaces 262 may include a network interface and/or a device interface configured to be communicatively coupled to one or more other devices. For example, interfaces 262 may include a transmitter, a receiver, or a combination thereof (e.g., a transceiver), and may enable wired communication, wireless communication, or a combination thereof. Additionally, or alternatively, the one or more interfaces 262 may include serial interfaces (e.g., universal serial bus (USB) interfaces or Institute of Electrical and Electronics Engineers (IEEE) 1394 interfaces), parallel interfaces, display adapters, audio adapters, and other interfaces. The one or more I/O devices 264 may include a mouse, a keyboard, pointing devices, a display device, the camera, speakers, microphones, touch screens, other I/O devices, or a combination thereof. Processor 290 may configured to send and/or receive data via the interface(s) 262 and/or the I/O device(s) 264.

[0090] During operation, dressing 216 is coupled to tissue site 220 so as to cover target tissue 236. Additionally, dressing 216 is coupled to device 210 via tube 214. In some implementations, processor 290 receives an input via I/O device(s) 264, such as a touchscreen, to select a pressure profile (e.g., 294) of multiple pressure profiles stored at memory 292, to initiate negative-pressure therapy, or both. Alternatively, the input may indicate a value of a negative-pressure to be provided and/or maintained. Responsive to the input, controller 260 (e.g., processor 290) generates one or more commands to initiate operations of one or more components of device 210. For example, processor 290 may access pressure profile 294 (e.g., a set-up profile or a maintenance profile). Additionally, or alternatively, processor 290 may activate and/or regulate reduced-pressure source 278, one or more valves 276, or both. In some implementations, processor 290 may control operation of reduced-pressure source 278, one or more valves 276 based on at least in part on the input (e.g., the pressure profile 294 selection or the value of the reduced or negative-pressure). [0091] Responsive to one or more signals (e.g., commands) from processor 290, reduced-pressure source 278 may apply negative-pressure to dressing 216. For example, negative-pressure developed by reduced-pressure source 278 may be delivered through tube 214 to connector 230 of dressing 216. Accordingly, the reduced-pressure source 278 can decrease a pressure in interior volume 238. Internal volume (e.g., a sealed therapeutic environment) and/or target tissue 236 may be isolated from an external environment (associated with an ambient pressure).

[0092] As negative-pressure is provided via pressure/fluid lumen (e.g., 221), pressure at dressing 216 may be communicated to first pressure sensor 272 and second pressure sensor 274 via first sense lumen (e.g., 224) and second sense lumen (e.g., 226), respectively. The pressure communicated by via first sense lumen (e.g., 224) and second sense lumen (e.g., 226) may be representative of the pressure at the target tissue 236. Each of first pressure sensor 272 and second pressure sensor 274 are configured to generate sensor data that is communicated to controller 260 (e.g., processor 290). The sensor data provided to controller 260 enables device 210 to track treatment provided to target tissue 236 via dressing 216. Based on the sensor data, controller 260 (e.g., processor 290) may initiate operation of one or more valves (e.g., 276) between an open position and a closed position. For example, processor 290 may be configured to adjust a particular valve in response to a comparison of the sensor data (indicating that a pressure within the interior volume (e.g., 238) to a threshold (e.g., 295).

[0093] In some implementations, processor 290 is configured to control reduced-pressure source 278 (e.g., a reduced-pressure source device) and/or one or more valves 276 based at least in part on the sensor data. For example, processor 290 may be configured to deactivate reduced-pressure source 278 in response to a determination that the sensor data indicates that a pressure within the interior volume (e.g., 238) is less than a first threshold (e.g., a first threshold pressure value). In some implementations, processor 290 is configured to operate at least one valve (e.g., 276) towards the open position upon or after deactivation of reduced-pressure source 278. To illustrate, the at least one valve may include the valve coupled to reduced-pressure source 278, the valve coupled to first pressure sensor 272, and/or the valve coupled to second pressure sensor 274. As another example, processor 290 may be configured to activate reduced-pressure source 278 in response to a determination that the sensor data indicates that a pressure within the interior volume (e.g., 238) is greater than or equal to a second threshold (e.g., a second threshold pressure value). Activation of reduced-pressure source 278 may decrease pressure within the interior volume (e.g., 238). In some implementations, processor 290 is configured to operate at least one valve (e.g., 276) towards the closed position upon or after activation of reduced-pressure source 278. The first threshold and the second threshold may have the same value. Alternatively, the first threshold and the second threshold may have different values (e.g., the second threshold may be greater than the first threshold).

[0094] In some implementations, valve 276 coupled to first pressure sensor 272 may be operated independent of valve 276 coupled to second pressure sensor 274. For example, controller 260 may operate valve 276 coupled to first pressure sensor 272 based on sensor data received from first pressure sensor 272 and/or based on a first set of one or more thresholds. Controller 260 may operate valve 276 coupled to second pressure sensor 274 based on sensor data received from second pressure sensor 274 and/or based on a second set of one or more thresholds. The first set of one or more thresholds and the second set of one or more thresholds may include one or more of the same threshold value(s) and/or one or more different threshold value(s). Additionally, or alternatively, in other implementations, controller 260 may operate one or more of the valves based on an average of sensor data of two or more sensors. For example, controller 260 may control one or more valves, such as the valve coupled to reduced-pressure source 278 based on an average of the sensor data (received from pressure sensors 272, 274) and a third set of one or more thresholds. The third set of one or more thresholds may include one or more of the same threshold value(s) and/or one or more different threshold value(s) as the first set of one or more thresholds and/or the second set of one or more thresholds.

[0095] Reduced-pressure provided by reduced-pressure source 278 via tube 214 can cause exudate, fluid, and/or another material to be drawn (e.g., removed) from target tissue 236 (e.g., tissue site 220) via tube 214 (e.g., reduced-pressure/fluid lumen) and second port/interface 282. Exudate, fluid, and/or another material removed via first port/interface 280 may be collected in fluid chamber 270 (e.g., a canister) for disposal. In some implementations, device 210 may include a sensor (not shown) coupled to controller 260 (e.g. processor 290) and configured to monitor a volume of fluid chamber 270. For example, processor 290 may receive sensor data from the sensor that indicates a fill level of fluid chamber 270. In response to a determination by processor 290 that the fill level is greater than or equal to a threshold (e.g., a threshold fill level value), processor 290 is configured to deactivate reduced- pressure source 278, operate at least one valve (e.g., 276) towards the open position, or both. Additionally, or alternatively, based on a determination by processor 290 that the fill level is greater than or equal to a threshold, processor 290 may initiate a notification (e.g., an alarm), such as a message via a display, an audio and/or visual notification, transmit a data message to another device, or a combination thereof.

[0096] Positive-pressure provided by positive-pressure source 279 via tube 214 can cause pressurized fluid (e.g., oxygen) to be provided to target tissue 236 (e.g., tissue site 220) via tube 214 (e.g., positive-pressure/fluid lumen) and second port/interface 282. In some implementations, device 210 may include a sensor and/or regulator (not shown) coupled to controller 260 (e.g. processor 290) and configured to monitor a pressure of the positive-pressure source 279 or the corresponding conduit 268 thereof. For example, processor 290 may receive sensor data from the sensor that indicates a pressure level of the regulator and may operate valve 276 to control a pressure and/or volume of positive-pressure source 279. Once a desired pressure of fluid is achieved, the pressurized fluid (e.g., oxygen) may be provided to target tissue 236. [0097] During providing of pressure by a pump (e.g., pump 150, reduced-pressure source 278, positive-pressure source 279, or a combination thereof), the pump may make noise. For example, the pump may be configured to be worn by a user and to output a first noise waveform (e.g., noise). The first noise waveform may be output because the pump is a diaphragm pump or other type of pump that is not substantially silent to the human ear (e.g., a piezoelectric pump). To reduce (or eliminate) the noise output by the pump, controller 260 may cause speaker 288 (which is disposed proximate to the pump) to output a second noise waveform to substantially cancel at least a portion of the first noise waveform. For example, speaker 288 may outwardly emit (e.g., emit into the surrounding air, as opposed to emitting into a particular channel, like an ear canal) the second noise waveform in order to reduce the perceived sound of the first noise waveform . In order to substantially cancel at least a portion of the first noise waveform, an amplitude of the second noise waveform is substantially inverted with respect to an amplitude of the first noise waveform, and a frequency of the second noise waveform is substantially the same as a frequency of the first noise waveform. Thus, at least a portion (e.g., a portion audible to the human ear, such as a lower frequency portion, a most annoying portion, etc.) of the first noise waveform output by the pump may be substantially cancelled by the second noise waveform output by speaker 288.

[0098] In some implementations, device 210 includes an “active” noise reduction system. For example, device 210 may include a first microphone (of one or more microphones 289) disposed near the pump (e.g., pump 150, reduced-pressure source 278, positive-pressure source 279, or a combination thereof). The first microphone may be configured to capture the first noise waveform and to provide first audio data 296 relating to the first noise waveform to controller 260. Controller 260 may be configured to adjust the second noise waveform based on first audio data 296 received from the first microphone. For example, controller 260 may adjust the second noise waveform by adjusting the amplitude of the second noise waveform, the frequency of the second noise waveform, or both, such that the amplitude and frequency of the second noise waveform track the amplitude and frequency of the first noise waveform. Thus, if the first noise waveform changes (e.g., due to changes in atmospheric pressure, temperature, drive voltage of the pump, reflections, etc.), the second noise waveform can be adjusted accordingly to substantially cancel at least a portion of the first noise waveform (and/or reflections thereof), thereby reducing (or eliminating) noise emitted by the pump. Additionally or alternatively, controller 260 may be further configured to adjust operation of the pump based on first audio data 296 from the first microphone. For example, controller 260 may reduce a PWM/duty cycle of the pump or a drive voltage applied to the pump in order to adjust the first noise waveform such that the second noise waveform substantially cancels at least a portion of the first noise waveform. As one example, reducing the PWM/duty cycle may reduce the frequency of the first noise waveform, which may cause the frequency of the first noise waveform to be substantially similar to the frequency of the second noise waveform. As another example, reducing the drive voltage may reduce the amplitude of the first noise waveform, which may cause the amplitude of the first noise waveform to be substantially similar to the amplitude of the second noise waveform.

[0099] In some implementations of the active noise reduction system, device 210 may further include a second microphone (of one or more microphones 289) configured to capture a combination of the first noise waveform and the second noise waveform and to provide second audio data 297 relating to the combination to controller 260. For example, the second microphone may be disposed after speaker 288 such that the second microphone is able to capture a combination of the first noise waveform and the second noise waveform. Based on the combination of noise waveforms, the second microphone may generate second audio data 297 which may be provided to controller 260. Controller 260 may be further configured to adjust the second noise waveform based on second audio data 297 received from the second microphone. For example, controller 260 may adjust the amplitude, the frequency, or both, of the second noise waveform in order to reduce an amplitude of the combination (or to better frequency match the first noise waveform and the second noise waveform). In this manner, second audio data 297 received from the second microphone (of one or more microphones 289) may be used as feedback data in adjusting the second noise waveform by controller 260. In other implementations, the first microphone captures the second audio data 297 relating to second audio data at a second time. The second audio data 297 may include audio data relating to the combination of noise at the first time and pump noise at the second time. The second audio data 297 may be used as feedback data to adjust the second noise waveform. The active noise reduction system may be further described with reference to FIG. 3.

[0100] In some implementations, device 210 includes a “passive” noise reduction system. For example, device 210 may not include any microphones to capture the first noise waveform (or a combination of the first noise waveform and the second noise waveform) for use in adjusting the second noise waveform. Instead, parameters of the second noise waveform may be stored (e.g., preprogrammed) in memory 292 as noise waveform data 295. For example, for a particular type of pump (such as a diaphragm pump), multiple pumps from different manufacturing sets may be studied to determine an average noise waveform that is output by the particular type of pump. Parameters of the average noise waveform may be stored as noise waveform data 295, and controller 260 may use noise waveform data 295 to generate the second noise waveform (corresponding to the average noise waveform). Thus, in the passive noise reduction system, the second noise waveform may be based on stored data and may not change based on the first noise waveform. Although the passive noise reduction system may not reduce noise as successfully as the active noise reduction system, the passive noise reduction system is less complex and uses less hardware (e.g., microphones and processing resources), such that the passive noise reduction system may be easier and cheaper to implement. Additionally, the passive noise reduction system uses less power, which enables longer runtimes and/or smaller battery sizes. [0101] In some such implementations, device 210 also includes atmospheric pressure sensor 287 configured to measure an atmospheric pressure and to provide atmospheric pressure data 298 to controller 260. For example, atmospheric pressure sensor 287 may be disposed proximate to the pump (e.g., pump 150, reduced-pressure source 278, positive-pressure source 279, or a combination thereof) and configured to measure the ambient atmospheric pressure near the pump. Because parameters (e.g., amplitude, frequency, etc.) of the first noise waveform may be related to the atmospheric pressure, atmospheric pressure data 298 may be provided to controller 260. Controller 260 may be further configured to generate the second noise waveform based on atmospheric pressure data 298. Generating the second noise waveform may include adjusting a base signal based on atmospheric pressure data 298 or selecting a particular set of parameters (e.g., amplitude, frequency, etc.) based on atmospheric pressure data 298. For example, sets of parameters (e.g., amplitude, frequency, etc.) may be stored for various atmospheric pressures as noise waveform data 295. Controller 260 may select a particular set of parameters based on atmospheric pressure data 298 (e.g., the atmospheric pressure indicated by atmospheric pressure data 298), and controller 260 may use the selected set of parameters to generate the second noise waveform. Stated another way, memory 292 is configured to store noise waveform data 295 corresponding to a plurality of different atmospheric pressures, and controller 260 is configured to generate the second noise waveform based on a portion of the noise waveform data 295 corresponding to atmospheric pressure data 298. The passive noise reduction system may be further described with reference to FIG. 4.

[0102] In some implementations, controller 260 may selectively deactivate speaker 288 (e.g., deactivate noise cancellation altogether) in certain situations, such as at times when noise reduction is not a priority or is not likely to be needed. For example, controller 260 may be configured to deactivate speaker 288 based on a battery level of device 210 failing to satisfy a battery threshold. To illustrate, if a battery level of device 210 is less than a threshold, such as 25%, 15%, or 10%, then controller 260 may deactivate speaker 288 (and stop production of the second noise waveform) to conserve battery power. In some implementations, conserving battery power when the battery is low may be more important than reducing noise. As another example, controller 260 may be configured to deactivate speaker 288 based on a drive voltage of the pump (e.g., pump 150, reduced-pressure source 278, positive-pressure source 279, or a combination thereof) failing to satisfy a drive voltage threshold. For example, if the drive voltage of the pump is sufficiently low (e.g., fails to satisfy the drive voltage threshold), the pump may not emit a significant amount of noise, and controller 260 may deactivate speaker 288 to conserve battery power when noise reduction is less useful. As another example, when the ambient noise level is below an ambient noise level threshold, noise cancellation may be deactivated. The ambient noise level may be determined by the one or more microphones 289.

[0103] In some implementations, controller 260 may selectively deactivate the one or more microphones 289 (e.g., deactivate active noise cancellation and/or switch to passive noise cancellation) in certain situations, such as at times when noise reduction is not a priority or when active noise cancellation is not likely to be needed. For example, controller 260 may be configured to deactivate the one or more microphones 289 based on a battery level of device 210 failing to satisfy a battery threshold. To illustrate, if a battery level of device 210 is less than a threshold, such as 25%, 15%, or 10%, then controller 260 may deactivate speaker 288 (and stop production of the second noise waveform) to conserve battery power. In some implementations, conserving battery power when the battery is low may be more important than actively reducing noise. As another example, controller 260 may be configured to deactivate the one or more microphones 289 based on a drive voltage of the pump (e.g., pump 150, reduced-pressure source 278, positive-pressure source 279, or a combination thereof) failing to satisfy a drive voltage threshold. For example, if the drive voltage of the pump is sufficiently low (e.g., fails to satisfy the drive voltage threshold), the pump may not emit a significant amount of noise, and controller 260 may deactivate the one or more microphones 289 to conserve battery power when noise reduction is less useful and passive noise cancellation can be used. As another example, when the ambient noise level is below an ambient noise level threshold, passive noise cancellation may be used.

[0104] In some implementations, device 210 may include acoustic insulation positioned to direct the first noise waveform in a particular direction. For example, the pump (e.g., pump 150, reduce- pressure source 278, positive-pressure source 279, or a combination thereof) may be at least partially surrounded by acoustic insulation. In some such implementations, one side of the pump may not be surrounded by acoustic insulation, or may be surrounded by less acoustic insulation, such that first noise waveform is directed in a particular direction. In such implementations, speaker 288 is configured to emit the second noise waveform in the particular direction. For example, speaker 288 may be positioned and directed in the particular direction such that the first noise waveform and the second noise waveform are both directed in the particular direction. An implementation that includes acoustic insulation is further described with reference to FIG. 5 A. In some other implementations, device 210 may include a metal core that surrounds at least a portion of the pump. The metal core is configured to reflect the first noise waveform and direct the first noise waveform in a particular direction. For example, the metal core may surround the pump on three sides, which may reflect the first noise waveform in a particular direction (e.g., toward the fourth side). In such implementations, speaker 288 is configured to emit the second noise waveform in the particular direction. For example, speaker 288 may be positioned and directed in the particular direction such that the first noise waveform and the second noise waveform are both directed in the particular direction. The metal core implementation may be similar to the acoustic insulation implementation, as further described with reference to FIG. 5A. [0105] In a particular implementation, a wound therapy device (e.g., 210) includes a pump (e.g., 150, 278, and/or 279) configured to be worn by a user. The pump is further configured to output a first noise waveform. The wound therapy device includes a speaker (e.g., 288) disposed proximate to the pump. The wound therapy device further includes a controller (e.g., 260) coupled to the pump and to the speaker. The controller is configured to cause the speaker to output a second noise waveform to substantially cancel at least a portion of the first noise waveform.

[0106] In another particular implementation, a kit for wound therapy includes a wound therapy device (e.g., 210) configured to be worn by a user. The wound therapy device includes a pump (e.g., 150, 278, or 279) configured to output a first noise waveform. The wound therapy device also includes a speaker (e.g., 288) disposed proximate to the pump. The wound therapy device further includes a controller (e.g., 260) coupled to the pump and to the speaker. The controller is configured to cause the speaker to output a second noise waveform to substantially cancel at least a portion of the first noise waveform. The kit further includes a dressing (e.g., 216) configured to be coupled to a wound site and to the pump. In some implementations, the kit further includes a tube (e.g., 214) configured to couple the pump to the dressing. In some implementations, the kit further includes a battery configured to power the wound therapy device. In some implementations, the kit further includes an adhesive configured to couple the dressing to a wound site of the user. In some implementations, the kit may include a package. For example, the package may include a box, a bag, a container, or the like. Additionally, or alternatively, the package may include a packaging medium (e.g., packaging material), such as foam, paper, or the like.

[0107] Thus, FIG. 2A illustrates system 200 for providing negative-pressure therapy. System 200 may advantageously reduce (or eliminate) noise from a pump of device 210. For example, speaker 288 may be operated by controller 260 to emit (e.g., output) a second noise waveform that substantially cancels at least a portion of a first noise waveform output by the pump. Thus, the second noise waveform may reduce noise output by the pump, which may improve a quality of life of a user. For example, the noise of a pump may not draw attention to the user as the user goes about their day-to-day activities or the noise of the pump may not impact a user’s ability to sleep. Thus, a noisier and more efficient pump, such as a diaphragm pump, can be used in a mobile, discreet wound therapy device without causing disruption to the wearer’s day-to-day activities, thereby improving a quality of life of the wearer.

[0108] FIG. 3 illustrates an example of a device 300 for reducing noise output by a pump. In some implementations, device 300 includes or corresponds to device 210 (e.g., a wound therapy device) of FIG. 2. However, device 300 is not so limited. For example, in some other implementations, device 300 may include or correspond to a blood pressure monitor, an infusion device, a wound drainage device, a mattress inflation device, or any other device that includes a pump that emits a noise waveform.

[0109] Device 300 includes a pump 302, a speaker 304, a controller 306, a first microphone 308, and an optional second microphone 310. In some implementations, pump 302 may include or correspond to pump 150, reduced-pressure source 278, and/or positive-pressure source 279, speaker 304 may include or correspond to speaker 152 or speaker 288, controller 306 may include or correspond to controller 154 or controller 260, and first microphone 308 and second microphone 310 may include or correspond to one or more microphones 289.

[0110] Pump 302 is configured to apply a pressure to a target, such as a wound site, as a non limiting example. The pressure may be positive or negative. Connections from pump 302 to the target are not shown for convenience. In some implementations, pump 302 is a diaphragm pump. Speaker 304 may be disposed proximate to pump 302. For example, speaker 304 may be disposed in a position such that sound output by speaker 304 mixes with sound output by pump 302, as further described herein. Controller 306 is coupled to pump 302 and speaker 304 and configured to control operation of pump 302 and speaker 304. For example, controller 306 may operate pump 302 to output pressure, such as according to a selected duty cycle. A duty cycle refers to an amount of time that pump 302 is active (e.g., receiving a drive voltage) during a particular time period. Additionally, controller 306 may operate speaker 304, as further described herein.

[0111] When pump 302 is active, pump 302 emits noise, which is represented by first noise waveform 312. For example, pump 302 may be a diaphragm pump or other type of pump that emits a “hum” or other sound when operating. To reduce the noise emitted by pump 302, controller 306 may cause speaker 304 to output a second noise waveform 314. Speaker 304 may outwardly emit second noise waveform 314 (e.g., emit second noise waveform 314 into the surrounding air, as compared to outputting a waveform into a channel, like an ear canal). Second noise waveform 314 may be configured to substantially cancel at least a portion of first noise waveform 312. For example, second noise waveform 314 may have substantially the same frequency as first noise waveform 312, and second noise waveform 314 may have an amplitude that is substantially inverted with respect to an amplitude of first noise waveform 312.

[0112] Device 300 includes an active noise cancellation system. In order to determine the amplitude and the frequency of first noise waveform 312 (so that the amplitude and frequency of second noise waveform 314 can be determined), device 300 includes first microphone 308. First microphone 308 may be disposed near pump 302. In some implementations, first microphone 308 may be coupled (e.g., attached) to pump 302. First microphone 308 may be configured to capture first noise waveform 312 (e.g., the sound output by pump 302) and to generate first audio data related to (e.g., indicative of) first noise waveform 312. Controller 306 may be coupled to first microphone 308 and configured to receive the first audio data from first microphone 308. Based on the first audio data, controller 306 may determine (or adjust) parameters of second noise waveform 314. For example, controller 306 may determine (or adjust) a frequency, an amplitude, or both, or second noise waveform 314 such that second noise waveform 314 substantially cancels at least a portion of first noise waveform 312. The portion may be a portion that is most audible and/or most annoying to human ears, such as a portion in a low frequency range that is audible to humans. For example, controller 306 may set (or adjust) the frequency of second noise waveform 314 to substantially match the frequency of first noise waveform 312. Additionally, or alternatively, controller 306 may set (or adjust) the amplitude of second noise waveform 314 to be substantially inverted with respect to the amplitude of first noise waveform 312. [0113] To illustrate, first noise waveform 312 and second noise waveform 314 are superimposed on graph 320. As can be seen in FIG. 3, first noise waveform 312 and second noise waveform 314 have substantially the same frequency and have amplitudes that are substantially inverted with respect to each other. Graph 322 shows a combination noise waveform 324, which is a combination of first noise waveform 312 and second noise waveform 314. As can be seen in FIG. 3, combination noise waveform 324 has a substantially smaller amplitude. Thus, combination noise waveform 324 may result in less noise output by device 300 because second noise waveform 314 may substantially cancel at least a portion (e.g., in a particular frequency range) of first noise waveform 312.

[0114] Because controller 306 receives first audio data from first microphone 308, controller 306 can actively adjust second noise waveform 314 based on changes in first noise waveform 312. For example, if the frequency or amplitude of first noise waveform 312 changes, such as due to a temperature or atmospheric pressure change, or due to a change in the operation timing of pump 302 (e.g., the duty cycle), first microphone 308 captures the changes to first noise waveform 312 and provides them to controller 306 in the form of the first audio data. Based on the first audio data, controller 306 may adjust the frequency, the amplitude, or both, of second noise waveform 314 to continue to track the frequency and/or amplitude of first noise waveform 312, thereby continuing to substantially cancel at least a portion of first noise waveform 312.

[0115] In some implementations, device 300 includes second microphone 310. Second microphone 310 may be disposed “after” (e.g., past an output of) speaker 304. Second microphone 310 may be configured to capture a combination of first noise waveform 312 and second noise waveform 314 (e.g., combination noise waveform 324) and to generate second audio data that is related to (e.g., indicative of) the combination. Controller 306 may be coupled to second microphone 310 and configured to receive the second audio data. Controller 306 may also be configured to adjust second noise waveform 314 based on the second audio data. For example, if the second audio data indicates that an amplitude of the combination (e.g., combination noise waveform 324) satisfies a threshold, controller 306 may adjust the amplitude of second noise waveform 314. In other examples, based on the second audio data, controller 306 may adjust the frequency of second noise waveform 314 (or both the amplitude and the frequency). In this manner, second microphone 310 may provide a second source of feedback information for the active noise cancellation performed by controller 306.

[0116] In some implementations, controller 306 may be configured to control the operation of pump 302 based on the first audio data, the second audio data, or both. For example, if controller 306 is unable to adjust second noise waveform 314 to sufficiently cancel at least a portion of first noise waveform 312, controller 306 may adjust the operation of pump 302, such as adjusting a duty cycle, an amount of drive voltage provided to pump 302, etc., to alter first noise waveform 312 such that second noise waveform 314 may substantially cancel at least a portion of first noise waveform 312.

[0117] In some implementations, controller 306 may selectively implement noise cancellation. In some such implementations, controller 306 may selectively implement noise cancellation to preserve battery power. For example, controller 306 may be configured to deactivate speaker 304 (or to otherwise prohibit emission of second noise waveform 314) based on a battery level of device 300 failing to satisfy a battery threshold. To further illustrate, if a battery level is below 20%, 15%, or 10%, as non-limiting examples, controller 306 may deactivate speaker 304 to preserve the remaining battery power. Additionally, or alternatively, controller 306 may be configured to selectively implement noise cancellation at times when the noise is more noticeable. For example, controller 306 may be configured to deactivate speaker 304 based on a duty cycle of pump 302 failing to satisfy a duty cycle threshold or based on an ambient noise level greater than an ambient noise threshold level (e.g., when pump 302 is quiet enough not to be noticeable to a wearer). Controller 306 may be further configured to activate speaker 304 based on the duty cycle satisfying the duty cycle threshold (e.g., when pump 302 is loud enough to be noticeable to the wearer).

[0118] Thus, FIG. 3 illustrates device 300 with an active noise cancelling system. For example, controller 306 may receive audio data from microphones (e.g., first microphone 308 and/or second microphone 310) and adjust second noise waveform 314 based on the audio data, such as by adjusting the frequency, the amplitude, or both. Controller 306 may adjust second noise waveform 314 to account for characteristics and/or changes of first noise waveform 312, such that second noise waveform 314 continues to substantially cancel at least a portion of first noise waveform 312, regardless of the characteristics or changes.

[0119] Although the example shown in FIG. 3 illustrates active noise canceling in a single direction, the device 300 may cancel noise in a three dimensional environment or a portion thereof. Thus, in some implementations, device 300 may include multiple pairs of speakers and microphones to actively cancel noise in different directions. Alternatively device 300 may include a speaker array and/or a microphone array to emit and receive in multiple directions. In some implementations, the device 300 receives reflections of partially canceled noise (e.g., reflections of 324), reflections of pump noise (e.g., reflections of 312), and reflections of “anti-noise” signals (e.g., reflections of 314) overtime and updates the “anti-noise” signals (e.g., 314 or adjusted 314) to cancel out such reflections or reduce the generation of such reflections.

[0120] FIG. 4 illustrates an example of a device 400 for reducing noise output by a pump. In some implementations, device 400 includes or corresponds to device 210 (e.g., a wound therapy device) of FIG. 2. However, device 400 is not so limited. For example, in some other implementations, device 400 may include or correspond to a blood pressure monitor, an infusion device, a wound drainage device, a mattress inflation device, or any other device that includes a pump that emits a noise waveform.

[0121] Device 400 includes a pump 402, a speaker 404, a controller 406, and an optional atmospheric pressure sensor 408. In some implementations, pump 402 may include or correspond to pump 150, reduced-pressure source 278, and/or positive-pressure source 279, speaker 304 may include or correspond to speaker 152 or speaker 288, and controller 306 may include or correspond to controller 154 or controller 260.

[0122] Pump 402 is configured to apply a pressure to a target, such as a wound site, as a non limiting example. The pressure may be positive or negative. Connections from pump 402 to the target are not shown for convenience. In some implementations, pump 402 is a diaphragm pump. Speaker 404 may be disposed proximate to pump 402. For example, speaker 404 may be disposed in a position such that sound output by speaker 404 mixes with sound output by pump 402, as further described herein. Controller 406 is coupled to pump 402 and speaker 404 and configured to control operation of pump 402 and speaker 404. For example, controller 406 may operate pump 402 to output pressure, such as according to a selected duty cycle. Additionally, controller 406 may operate speaker 404, as further described herein.

[0123] When pump 402 is active, pump 402 emits noise, which is represented by first noise waveform 410. For example, pump 402 may be a diaphragm pump or other type of pump that emits a “hum” or other sound when operating. To reduce the noise emitted by pump 402, controller 406 may cause speaker 404 to output a second noise waveform 412. Speaker 404 may outwardly emit second noise waveform 412 (e.g., emit second noise waveform 412 into the surrounding air, as compared to outputting a waveform into a channel, like an ear canal). Second noise waveform 412 may be configured to substantially cancel at least a portion of first noise waveform 410. For example, second noise waveform 412 may have substantially the same frequency as first noise waveform 410, and second noise waveform 412 may have an amplitude that is substantially inverted with respect to an amplitude of first noise waveform 410.

[0124] Device 400 includes a “passive” noise cancellation system. For example, device 400 may not include any microphones, and controller 406 may not adjust second noise waveform 412 based on audio data generated by capturing first noise waveform 410. Instead, parameters of second noise waveform 412 may be stored at a memory of controller 406, and second noise waveform 412 may not change regardless of operating conditions of pump 402. For example, pump 402 may include a particular type of pump, and multiple pumps of the particular type of pump (from different manufacturing batches) may be studied to determine an average noise waveform output by the pumps. The parameters of the average noise waveform may be stored (e.g., preprogrammed) at the memory of controller 406 such that second noise waveform 412 is the average noise waveform. Although first noise waveform 410 may differ from the average noise waveform, the difference may be small enough such that a substantial percentage of first noise waveform 410 is canceled by second noise waveform 412 (e.g., the average noise waveform).

[0125] To illustrate, first noise waveform 410 and second noise waveform 412 are superimposed on graph 420. As can be seen in FIG. 4, first noise waveform 410 and second noise waveform 412 have substantially the same frequency and have amplitudes that are substantially inverted with respect to each other. Graph 422 shows a combination noise waveform 424, which is a combination of first noise waveform 410 and second noise waveform 412. As can be seen in FIG. 4, combination noise waveform 424 has a substantially smaller amplitude. Thus, combination noise waveform 424 may result in less noise output by device 400 because second noise waveform 412 may substantially cancel at least a portion (e.g., in a particular frequency range) of first noise waveform 410. Different devices having different types of pumps may store different parameters (e.g., frequency, amplitude, etc.) for second noise waveform 412. Although the passive noise cancellation system may not cancel noise as well as the active noise cancellation system described with reference to FIG. 3, the passive noise cancellation system uses less hardware (e.g., no microphones) and is less complex (e.g., in terms of resources of controller 406) and may be cheaper to manufacture than the active noise cancellation system.

[0126] In some implementations, the passive noise cancellation system may generate or adjust second noise waveform 412 based on a parameter of pump 402. For example, the memory of controller 406 may store sets of parameters for various levels of pump drive level/PWM/duty cycle, and controller 406 may generate second noise waveform 412 based on the level of pump drive/PWM/duty cycle. For example, speaker 406 may emit an initial noise waveform when the passive noise cancellation system is started based on a reference signal or the pump drive level (e.g., drive voltage). As the pump drive level/PWM/duty cycle changes, the parameters of second noise waveform 412 may change based on the stored values corresponding to the changes in pump drive level/PWM/duty cycle.

[0127] In some implementations, the passive noise cancellation system may have an active element. For example, device 400 may include atmospheric pressure sensor 408. Atmospheric pressure sensor 408 may be configured to measure the ambient atmospheric pressure and generate atmospheric pressure data related to (e.g., indicative of) the ambient atmospheric pressure. Controller 406 may be coupled to atmospheric pressure sensor 408 and configured to receive the atmospheric pressure data. Controller 406 may be further configured to generate second noise waveform 412 based on the atmospheric pressure data. For example, the memory of controller 406 may store multiple sets of noise waveform parameters corresponding to different atmospheric pressures, and controller 406 may select the parameters (e.g., amplitude, frequency, etc.) for second noise waveform 412 from the multiple sets of noise waveform parameters based on the atmospheric pressure indicated by the atmospheric pressure data. To further illustrate, multiple pumps of the particular type may be studied to determine average noise waveforms at different atmospheric pressures, and the parameters of the different average noise waveforms may be stored at the memory of controller 406. When atmospheric pressure data is received, controller 406 may retrieve the parameters corresponding to the atmospheric pressure for use in initiating generation of second noise waveform 412. Although described in the context of an atmospheric pressure sensor, in other implementations, device 400 may include a temperature sensor, and the memory of controller 406 may store multiple different noise waveform parameters corresponding to different temperatures for use in initiating output of second noise waveform 412. Although atmospheric pressure sensor 408 is described as being included in the passive noise cancelling system of FIG. 4, in some implementations, atmospheric pressure sensor 408 (and/or a temperature sensor) may be included in the active noise cancellation system of FIG. 3.

[0128] In some implementations, controller 406 may selectively implement noise cancellation. In some such implementations, controller 406 may selectively implement noise cancellation to preserve battery power. For example, controller 406 may be configured to deactivate speaker 404 (or to otherwise prohibit emission of second noise waveform 412) based on a battery level of device 400 failing to satisfy a battery threshold. To further illustrate, if a battery level is below 20%, 15%, or 10%, as non-limiting examples, controller 406 may deactivate speaker 404 to preserve the remaining battery power. Additionally, or alternatively, controller 406 may be configured to selectively implement noise cancellation at times when the noise is more noticeable. For example, controller 406 may be configured to deactivate speaker 404 based on a duty cycle of pump 402 failing to satisfy a duty cycle threshold or ambient noise greater than an ambient noise threshold level (e.g., when pump 402 is quiet enough not to be noticeable to a wearer). Controller 406 may be further configured to activate speaker 404 based on the duty cycle satisfying the duty cycle threshold (e.g., when pump 402 is loud enough to be noticeable to the wearer).

[0129] Thus, FIG. 4 illustrates device 400 with a passive noise cancelling system. For example, controller 406 may store parameters for use in generating second noise waveform 412 and may not adjust second noise waveform 412 during operation. Such a noise cancellation system may less complex, use less hardware, and use less processing resources than an active noise cancellation system. Additionally, in some implementations, controller 406 may adjust second noise waveform 412 based on atmospheric pressure data (or temperature data).

[0130] FIG. 5A illustrates an example of a device 500 for reducing noise output by a pump. In some implementations, device 500 includes or corresponds to device 210 (e.g., a wound therapy device) of FIG. 2. However, device 500 is not so limited. For example, in some other implementations, device 500 may include or correspond to a blood pressure monitor, an infusion device, a wound drainage device, a mattress inflation device, or any other device that includes a pump that emits a noise waveform.

[0131] Device 500 includes a pump 502, a speaker 504, a controller 506, and acoustic insulation 508. In some implementations, pump 502 may include or correspond to pump 150, reduced-pressure source 278, and/or positive-pressure source 279, speaker 504 may include or correspond to speaker 152 or speaker 288, and controller 506 may include or correspond to controller 154 or controller 260. [0132] Pump 502 is configured to apply a pressure to a target, such as a wound site, as a non limiting example. The pressure may be positive or negative. Connections from pump 502 to the target are not shown for convenience. In some implementations, pump 502 is a diaphragm pump. Speaker 504 may be disposed proximate to pump 502. For example, speaker 504 may be disposed in a position such that sound output by speaker 504 mixes with sound output by pump 502. Controller 506 is coupled to pump 502 and speaker 504 and configured to control operation of pump 502 and speaker 504. For example, controller 506 may operate pump 502 to output pressure, such as according to a selected duty cycle. Additionally, controller 506 may operate speaker 504, as further described herein.

[0133] When pump 502 is active, pump 502 emits noise, which is represented by first noise waveform 510. For example, pump 502 may be a diaphragm pump or other type of pump that emits a “hum” or other sound when operating. To reduce the noise emitted by pump 502, controller 506 may cause speaker 504 to output a second noise waveform 512. Speaker 504 may outwardly emit second noise waveform 512 (e.g., emit second noise waveform 512 into the surrounding air, as compared to outputting a waveform into a channel, like an ear canal). Second noise waveform 512 may be configured to substantially cancel at least a portion of first noise waveform 510. For example, second noise waveform 512 may have substantially the same frequency as first noise waveform 510, and second noise waveform 512 may have an amplitude that is substantially inverted with respect to an amplitude of first noise waveform 510.

[0134] Device 500 may include acoustic insulation 508 to dampen (e.g., reduce) the noise output by pump 502 and/or to focus the noise in a particular direction. For example, acoustic insulation 508 may be positioned to direct first noise waveform 510 in a particular direction. To further illustrate, acoustic insulation 508, such as foam, wool, vinyl, sound-insulating coatings, or other insulating materials, may surround pump 502 on three sides such that first noise waveform 510 is emitted from a fourth side. Speaker 504 may be disposed on the fourth side and aligned such that second noise waveform 512 is also emitted in the particular direction. Thus, noise reduction may be performed by noise insulation in many directions and by noise cancellation (e.g., due to second noise waveform 512) in a particular direction. In some implementations, pump 502 is mounted in a noise suppression housing (e.g., acoustic insulation 508) that provides noise insulation in one or more directions (but not all directions). The noise suppression housing may be a formed structure of closed cell, acoustic foam. As one example, the acoustic foam may be a “dense” acoustic foam, such as foam made from a Melamine Formaldehyde thermoset polymer. One illustrative, non-limiting example of such as foam is Basotect by BASF, a registered trademark of BASF Corporation.

[0135] In other implementations, instead of being surrounded by acoustic insulation 508, pump 502 may be at least partially surrounded by a metal core. For example, inner sections of the device 500 may include 0.5 to 2 mm thick aluminum or steel to provide a solid metal core and defining a chamber (including pump 502) such that some of first waveform 510 (or waveforms) is/are reflected reducing the need for foam to provide insulation. The metal core may be configured to direct the first waveform(s) 510 and reflections thereof in less than all directions (e.g., a single direction) that the first waveform(s) 510 can be directionally cancelled. For example, the metal core may reflect noise waveforms such that most (if not all) of the noise waveforms leave pump 502 in a particular direction. In some such implementations, speaker 504 may be disposed on the same side and aligned such that second noise waveform 512 is also emitted in the particular direction. Thus, use of a metal core may direct first noise waveform 510 in the same direction as second noise waveform 512, leading to improved noise cancellation.

[0136] In a particular implementation, an apparatus (e.g., 110, 210, 300, 400, or 500) includes means for outputting audible noise (e.g., 150, 278, 279, 302, 402, or 502). The audible noise corresponds to a first noise waveform (e.g., 312, 410, or 510). The apparatus also includes means for directing (e.g., 508, 530, or both) the audible noise into an environment in a particular direction. The apparatus includes means for outputting (e.g., 152, 288, 304, 404, or 504) a second noise waveform (e.g., 314, 412, or 512) in the particular direction and disposed proximate to the means for outputting audible noise. The apparatus further includes means for controlling (e.g., 154, 260, 306, 406, or 506) the means for outputting the second noise waveform to cause the means for outputting the second noise waveform to output the second noise waveform to substantially cancel at least a portion of the first noise waveform in the environment.

[0137] FIG. 5B depicts an image of a prototype device for reducing noise output by a pump. In a particular implementation, the prototype device may include or correspond to an implementation of the device 500 of FIG. 5A. For example, a housing 530 of the prototype device may include insulation or be configured to direct noise in a single direction, such as downward as illustrated in FIG. 5B.

[0138] The prototype device includes pump 502, speaker 504, and controller 506 (e.g., an active noise cancellation controller). In some implementations, as illustrated in FIG. 5B, a fan may be disposed adjacent (e.g., over) speaker 504. The prototype device also includes a first microphone 520 and a second microphone 522 as part of an active noise cancellation system. In some implementations, first microphone 520 and second microphone 522 include or correspond to first microphone 308 and second microphone 310 of FIG. 3. The components illustrated in FIG. 5B may be included in housing 530. The prototype device may operate as described with reference to FIGS. 3-5A.

[0139] FIG. 6 illustrates a method 600 of operating a wound therapy device. Method 600 may be performed at or by system 100 or 200, devices 300, 400, or 500, and/or by controller 260, 306, 406, or 506. Method 600 includes initiating output of a second noise waveform at a speaker of a wound therapy device to substantially cancel at least a portion of a first noise waveform output by a pump of the wound therapy device, at 610. For example, controller 260 of device 210 may cause speaker 288 to output a second noise waveform to substantially cancel at least a portion of a first noise waveform output by pump 150, reduced-pressure source 278, positive-pressure source 279, or a combination thereof. [0140] Method 600 also includes receiving audio data from a first microphone disposed near the pump, at 612. The audio data is related to the first noise waveform. For example, controller 260 may receive first audio data 296 from a first microphone of one or more microphones 289. As another example, controller 306 may receive first audio data from first microphone 308, the first audio data indicative of first noise waveform 312 output by pump 302.

[0141] Method 600 further includes adjusting the second noise waveform based on the audio data to continue substantially cancelling at least a portion of the first noise waveform, at 614. For example, controller 260 adjusts the second noise waveform output by speaker 288 to continue to substantially cancel the first noise waveform output by pump 150, reduced-pressure source 278, positive-pressure source 279, or a combination thereof. As another example, controller 306 adjusts second noise waveform 314 output by speaker 304 to continue to substantially cancel at least a portion of first noise waveform 312 output by pump 302.

[0142] In some implementations, adjusting the second noise waveform includes adjusting an amplitude of the second noise waveform based on an amplitude of the first noise waveform. For example, controller 260 may adjust an amplitude of the second noise waveform to be an inversion of an amplitude of the first noise waveform. As another example, controller 306 may adjust the amplitude of second noise waveform 314 to be an inversion of the amplitude of first noise waveform 312. Additionally, or alternatively, adjusting the second noise waveform includes adjusting a frequency of the second noise waveform based on a frequency of the first noise waveform. For example, controller 260 may adjust a frequency of the second noise waveform to substantially match a frequency of the first noise waveform. As another example, controller 306 may adjust the amplitude of second noise waveform 314 to substantially match the frequency of first noise waveform 312.

[0143] In some implementations, method 600 further includes receiving second audio data from a second microphone configured to capture a combination of the first noise waveform and the second noise waveform. For example, controller 260 may receive second audio data from a second microphone of one or more microphones 289. As another example, controller 306 may receive second audio data from second microphone 310. In some such implementations, method 600 further includes adjusting the second noise waveform based on the second audio data. For example, controller 260 may further adjust the second noise waveform based on the second audio data (e.g., using the second audio data as feedback data). As another example, controller 306 may adjust second noise waveform 314 based on the second audio data. In some such implementations, further adjusting the second noise waveform includes adjusting an amplitude of the second noise waveform, a frequency of the second noise waveform, or both. [0144] Thus, method 600 describes performing active noise cancelling on a noise waveform output by a pump. For example, in response to receiving audio data from a first microphone disposed near a pump, a second noise waveform is adjusted, such as by adjusting the frequency, the amplitude, or both. Adjusting the second noise waveform may account for characteristics and/or changes of the first noise waveform output by the pump, such that the second noise waveform continues to substantially cancel at least a portion of the first noise waveform, regardless of the characteristics or changes.

[0145] FIG. 7 illustrates a method 700 of operating a wound therapy device. Method 700 may be performed at or by system 100 or 200, devices 300, 400, or 500, and/or by controller 260, 306, 406, or 506. Method 700 includes receiving first atmospheric pressure data indicating a first atmospheric pressure from an atmospheric pressure sensor of a wound therapy device, at 710. For example, controller 260 may receive atmospheric pressure data 298 from atmospheric pressure sensor 287. As another example, controller 406 may receive atmospheric pressure data from atmospheric pressure sensor 408.

[0146] Method 700 includes initiating output of a second noise waveform from a speaker of the wound therapy device to substantially cancel at least a portion of a first noise waveform output by a pump of the wound therapy device, at 712. The second noise waveform is based on the first atmospheric pressure. For example, controller 260 may initiate output of a second noise waveform at speaker 288 to substantially cancel at least a portion of a first noise waveform output by pump 150, reduced-pressure source 278, positive-pressure source 279, or a combination thereof. The second noise waveform is based on noise waveform data 295 and the atmospheric pressure. For example, controller 260 may select an amplitude and/or frequency for the second noise waveform that corresponds to the atmospheric pressure from noise waveform data 295. As another example, controller 406 may initiate output of second noise waveform 412 from speaker 404 based on the atmospheric pressure data from atmospheric pressure sensor 408.

[0147] Method 700 also includes receiving second atmospheric pressure data indicating a second atmospheric pressure from the atmospheric pressure sensor, at 714. The second atmospheric pressure is different from the first atmospheric pressure. For example, controller 260 may receive second atmospheric pressure data (included in atmospheric pressure data 298) that indicates a change in the atmospheric pressure from atmospheric pressure sensor 287. As another example, controller 406 may receive additional atmospheric pressure data from atmospheric pressure sensor 408.

[0148] Method 700 further includes adjusting the second noise waveform based on the second atmospheric pressure, at 716. For example, controller 260 may adjust the second noise waveform based on the second atmospheric pressure indicated by atmospheric pressure data 298. As another example, controller 406 may adjust second noise waveform 412 based on the additional atmospheric pressure data. [0149] In some implementations, adjusting the second noise waveform includes adjusting an amplitude of the second noise waveform based on the atmospheric pressure. For example, controller 260 may adjust the amplitude of the second noise waveform based on atmospheric pressure data 298. As another example, controller 406 may adjust the amplitude of second noise waveform 412 based on the additional atmospheric pressure data. Additionally, or alternatively, adjusting the second noise waveform includes adjusting a frequency of the second noise waveform based on the atmospheric pressure. For example, controller 260 may adjust the frequency of the second noise waveform based on atmospheric pressure data 298. As another example, controller 406 may adjust the frequency of second noise waveform 412 based on the additional atmospheric pressure data.

[0150] In some implementations, one or more characteristics of the second noise waveform are selected based on the first atmospheric pressure. For example, controller 260 may select one or more characteristics (e.g., parameters) of the second noise waveform based on the atmospheric pressure data 298. As another example, controller 406 may select one or more characteristics (e.g., parameters) of second noise waveform 412 based on the atmospheric pressure data. In some such implementations, the one or more characteristics include an amplitude of the second noise waveform, a frequency of the second noise waveform, or both.

[0151] Thus, method 700 describes a passive noise cancelling operation that can adjust parameters of a second noise waveform based on atmospheric pressure data. For example, a memory of a controller may store multiple sets of noise waveform parameters corresponding to different atmospheric pressures, and a particular set of noise waveform parameters may be selected for use in generating the second noise waveform based on the atmospheric pressure data. The passive noise cancelling method may be less complex, use less hardware, and be less expensive than an active noise cancelling method.

[0152] FIG. 8 illustrates a method 800 of operating a wound therapy device. Method 800 may be performed at or by system 100 or 200, devices 300, 400, or 500, and/or by controller 260, 306, 406, or 506. Method 800 includes determining a battery level of a wound therapy device, at 810. The wound therapy device includes a pump configured to output noise. For example, controller 260 may determine a battery level of therapy device 210. Therapy device 210 may include a pump (e.g., pump 150, reduced-pressure source 278, and/or positive-pressure source 279) that is configured to output noise while in operation, such as a diaphragm pump or other mechanical pump.

[0153] Method 800 includes performing one of active noise cancellation or passive noise cancellation based on the battery level and a battery threshold, at 812. Performing the active noise cancellation or the passive noise cancellation includes emitting, from one or more speakers, one or more noise waveforms in one or more directions to substantially cancel at least a portion of the noise. For example, controller 260 may perform active noise cancellation (e.g., enabling one or more microphones 289 and speaker 288) or passive noise cancellation (e.g., enabling speaker 288 but not one or more microphones 289) based on a comparison of the battery level to a battery threshold. Speaker 288 may include one or more speakers configured to output one or more noise waveforms in one or more directions to substantially cancel at least a portion of the noise output by the pump.

[0154] In some implementations, performing the active noise cancellation further includes receiving first audio data from a microphone and generating the one or more noise waveforms based on the first audio data. The first audio data is related to the noise output by the pump. For example, controller 260 may receive first audio data 296 from one or more microphones 289 and may generate (e.g., generate a base waveform or adjust an already generated waveform) based on first audio data 296. Additionally, or alternatively, performing the passive noise cancellation further includes selecting one or more attributes of the one or more noise waveforms from noise waveform data stored at a memory. For example, controller 260 may cause speaker 288 to generate one or more noise waveforms having attributes designated by noise waveform data 295 stored at memory 292. Additionally, or alternatively, the one or more speakers may include a speaker array configured to output multiple noise waveforms in multiple directions. For example, speaker 288 may include a speaker array configured to output multiple noise waveforms in multiple directions.

[0155] Thus, method 800 describes a method of operating a wound therapy device to substantially cancel the noise output by a pump of the wound therapy device . The wound therapy device may perform active or passive noise cancellation based on a battery level of a battery of the wound therapy device and a battery threshold, thereby enabling the wound therapy device to perform active noise cancellation when there is sufficient battery power to support operation of one or more microphones, and to perform passive noise cancellation when battery power is low.

[0156] One or more of the methods 600-800 of FIGS. 6-8 may be implemented in a computer- readable storage device storing instructions that, when executed by a processor, cause the processor to perform the operations of the corresponding method.

[0157] It is noted that one or more operations described with reference to one of the methods of FIGS. 6-8 may be combined with one or more operations of another of FIGS. 6-8. For example, one or more operations of method 600 may be combined with one or more operations of method 700. Additionally, or alternatively, one or more operations described above with reference to FIGS. 1-5B may be combined with one or more operations of FIGS. 6-8, or a combination of FIGS. 6-8.

[0158] The above specification and examples provide a complete description of the structure and use of illustrative examples. Although certain aspects have been described above with a certain degree of particularity, or with reference to one or more individual examples, those skilled in the art could make numerous alterations to aspects of the present disclosure without departing from the scope of the present disclosure. As such, the various illustrative examples of the methods and systems are not intended to be limited to the particular forms disclosed. Rather, they include all modifications and alternatives falling within the scope of the claims, and implementations other than the ones shown may include some or all of the features of the depicted examples. For example, elements may be omitted or combined as a unitary structure, connections may be substituted, or both. Further, where appropriate, aspects of any of the examples described above may be combined with aspects of any of the other examples described to form further examples having comparable or different properties and/or functions, and addressing the same or different problems. Similarly, it will be understood that the benefits and advantages described above may relate to one example or may relate to several examples. Accordingly, no single implementation described herein should be construed as limiting and implementations of the disclosure may be suitably combined without departing from the teachings of the disclosure.

[0159] The previous description of the disclosed implementations is provided to enable a person skilled in the art to make or use the disclosed implementations. Various modifications to these implementations will be readily apparent to those skilled in the art, and the principles defined herein may be applied to other implementations without departing from the scope of the disclosure. Thus, the present disclosure is not intended to be limited to the implementations shown herein but is to be accorded the widest scope possible consistent with the principles and novel features as defined by the following claims. The claims are not intended to include, and should not be interpreted to include, means-plus- or step-plus-function limitations, unless such a limitation is explicitly recited in a given claim using the phrase(s) “means for” or “step for,” respectively.

Claims

1. A wound therapy device comprising: a pump configured to be worn by a user, the pump further configured to output a first noise waveform; a speaker disposed proximate to the pump; and a controller coupled to the pump and to the speaker, the controller configured to cause the speaker to output a second noise waveform to substantially cancel at least a portion of the first noise waveform.

2. The wound therapy device of claim 1, wherein an amplitude of the second noise waveform is substantially inverted with respect to an amplitude of the first noise waveform, and wherein the second noise waveform is output into an environment to cancel at least a portion of the first noise waveform in the environment.

3. The wound therapy device of any of claims 1-2, wherein a frequency of the second noise waveform is substantially the same as a frequency of the first noise waveform.

4. The wound therapy device of any of claims 1-3, further comprising acoustic insulation coupled to the pump and positioned to direct the first noise waveform in a particular direction.

5. The wound therapy device of claim 4, wherein the speaker is configured to emit the second noise waveform in the particular direction.

6. The wound therapy device of any of claims 1-5, further comprising a metal core surrounding at least a portion of the pump, the metal core configured to reflect the first noise waveform in a particular direction.

7. The wound therapy device of claim 6, wherein the speaker is configured to emit the second noise waveform in the particular direction.

8. The wound therapy device of any of claims 1-7, wherein the pump comprises a diaphragm pump.

9. The wound therapy device of any of claims 1-8, wherein the pump is configured to apply a negative pressure to a dressing.

10. The wound therapy device of any of claims 1-9, further comprising a first microphone disposed near the pump, the first microphone configured to capture the first noise waveform and to provide audio data relating to the first noise waveform to the controller.

11. The wound therapy device of claim 10, wherein the controller is further configured to generate the second noise waveform based on the audio data received from the first microphone.

12. The wound therapy device of any of claims 10-11, further comprising a second microphone configured to capture a combination of the first noise waveform and the second noise waveform and to provide second audio data relating to the combination to the controller.

13. The wound therapy device of claim 12, wherein the controller is further configured to adjust the second noise waveform based on the second audio data received from the second microphone, generate a third noise waveform to substantially cancel reflections of the first noise waveform or the second noise waveform, or both.

14. The wound therapy device of any of claims 10-13, wherein the controller is further configured to adjust operation of the pump based on the audio data received from the first microphone.

15. The wound therapy device of any of claims 1-14, further comprising an atmospheric pressure sensor configured to measure an atmospheric pressure and to provide atmospheric pressure data to the controller.

16. The wound therapy device of claim 15, wherein the controller is further configured to generate the second noise waveform based on the atmospheric pressure data.

17. The wound therapy device of claim 16, wherein the controller comprises a memory configured to store noise waveform audio data corresponding to a plurality of different atmospheric pressures, and wherein the controller is further configured to generate the second noise waveform based on a portion of the noise waveform audio data corresponding to the atmospheric pressure data.

18. The wound therapy device of any of claims 1-17, wherein the controller is further configured to deactivate the speaker based on a battery level failing to satisfy a battery threshold or to switch to passive noise cancellation based on the battery level failing to satisfy the battery threshold.

19. The wound therapy device of any of claims 1-18, wherein the controller is further configured to deactivate the speaker based on a duty cycle of the pump failing to satisfy a duty cycle threshold.

20. A method comprising: initiating output of a second noise waveform at a speaker of a wound therapy device to substantially cancel at least a portion of a first noise waveform output by a pump of the wound therapy device; receiving audio data from a first microphone disposed near the pump, the audio data related to the first noise waveform; and adjusting the second noise waveform based on the audio data to continue substantially cancelling at least a portion of the first noise waveform.

21. The method of claim 20, wherein adjusting the second noise waveform comprises adjusting an amplitude of the second noise waveform based on an amplitude of the first noise waveform determined from the audio data.

22. The method of any of claims 20-21, wherein adjusting the second noise waveform comprises adjusting a frequency of the second noise waveform based on a frequency of the first noise waveform determined from the audio data.

23. The method of any of claims 20-22, further comprising: receiving second audio data from a second microphone configured to capture a combination of the first noise waveform and the second noise waveform; and adjusting the adjusted second noise waveform based on the second audio data.

24. The method of claim 23, wherein further adjusting the adjusted second noise waveform comprises adjusting an amplitude of the adjusted second noise waveform, a frequency of the adjusted second noise waveform, or both.

25. The method of claim 20, further comprising deactivating active noise cancellation or switching to passive noise cancellation based on determining that a battery level of a battery of the wound therapy device fails to satisfy a battery threshold.

26. A method comprising: receiving first atmospheric pressure data indicating a first atmospheric pressure from an atmospheric pressure sensor of a wound therapy device; initiating output of a second noise waveform from a speaker of the wound therapy device to substantially cancel at least a portion of a first noise waveform output by a pump of the wound therapy device, the second noise waveform based on the first atmospheric pressure; receiving second atmospheric pressure data indicating a second atmospheric pressure from the atmospheric pressure sensor, the second atmospheric pressure different from the first atmospheric pressure; and adjusting the second noise waveform based on the second atmospheric pressure.

27. The method of claim 26, wherein adjusting the second noise waveform comprises adjusting an amplitude of the second noise waveform based on the second atmospheric pressure.

28. The method of any of claims 26-27, wherein adjusting the second noise waveform comprises adjusting a frequency of the second noise waveform based on the second atmospheric pressure.

29. The method of any of claims 26-28, wherein one or more characteristics of the second noise waveform are selected based on the first atmospheric pressure.

30. The method of claim 29, wherein the one or more characteristics comprise an amplitude of the second noise waveform, a frequency of the second noise waveform, or both.

31. A method comprising: determining a battery level of a wound therapy device, the wound therapy device comprising a pump configured to output noise; performing one of active noise cancellation or passive noise cancellation based on the battery level and a battery threshold, wherein performing the active noise cancellation or the passive noise cancellation comprises emitting, from one or more speakers, one or more noise waveforms in one or more directions to substantially cancel at least a portion of the noise.

32. The method of claim 31, wherein performing the active noise cancellation further comprises receiving first audio data from a microphone and generating the one or more noise waveforms based on the first audio data, the first audio data related to the noise output by the pump.

33. The method of any of claims 31-32, wherein performing the passive noise cancellation further comprises selecting one or more attributes of the one or more noise waveforms from noise waveform data stored at a memory.

34. The method of any of claims 31-33, wherein the one or more speakers comprise a speaker array configured to output multiple noise waveforms in multiple directions.

35. A kit for wound therapy, the kit comprising : a wound therapy device configured to be worn by a user, the wound therapy device comprising: a pump configured to output a first noise waveform; a speaker disposed proximate to the pump; and a controller coupled to the pump and to the speaker, the controller configured to cause the speaker to output a second noise waveform to substantially cancel at least a portion of the first noise waveform; and a dressing configured to be coupled to a wound site and to the pump.

36. The kit of claim 35, further comprising a tube configured to couple the pump to the dressing.

37. The kit of any of claims 35-36, further comprising a battery configured to power the wound therapy device.

38. The kit of any of claims 35-37, further comprising an adhesive configured to couple the dressing to a wound site of the user.

39. An apparatus comprising: means for outputting audible noise, the audible noise corresponding to a first noise waveform; means for directing the audible noise into a particular direction; means for outputting a second noise waveform into an environment in the particular direction, the means for outputting the second noise waveform disposed proximate to the means for outputting audible noise; and means for controlling the means for outputting the second noise waveform to cause the means for outputting the second noise waveform to output the second noise waveform to substantially cancel at least a portion of the first noise waveform in the environment.

40. The apparatus of claim 39, wherein the apparatus comprises a blood pressure monitor.

41. The apparatus of claim 39, wherein the apparatus comprises an infusion device.

42. The apparatus of claim 39, wherein the apparatus comprises a wound drainage device.

43. The apparatus of claim 39, wherein the apparatus comprises a mattress inflation device.