WO2020238034A1 - Saliva sampling and testing device - Google Patents

Abstract

A saliva sampling and testing device, comprising a detection container (300), a sampling body (700), a liquid storage assembly, a transfer body (600), and a sampling handle (200). The liquid storage assembly comprises a liquid storage body (500), the sampling handle (200) has a cylindrical shape, and the sampling body (700) is fixed to one end of the sampling handle (200) and at least partially protrudes from the sampling handle (200). The liquid storage assembly can extend into an inner cavity of the sampling handle (200) and can be detachably and fixedly connected to the sampling handle (200); the transfer body (600) is accommodated in the inner cavity of the sampling handle (200) and separately connected to the liquid storage body (500) and the sampling body (700); the sampling handle (200) can extend into the inner cavity of the detection container (300), and the sampling body (700) can extrude the detection container (300) to release a saliva sample. Two test samples can be provided by one acquisition process to realize the functions of liquid storage and re-examination.

Description

Saliva sampling device

References to related applications

The present invention claims the priority of the invention patent application filed in China on May 31, 2019, named "saliva sampling device" and application number 201910468440.2, the entire content of which is incorporated herein by reference.

Technical field

The invention relates to the field of in vitro diagnostics, and more specifically, to a saliva sampling and testing device.

Background technique

The saliva sampling and testing device in the prior art is usually disposable, and it can only perform one saliva sample detection after one saliva collection. In actual operation, for example, when it is necessary to detect whether the subject is taking drugs, when the first test result of the saliva sample is positive, the saliva sample usually needs to be retested to ensure the accuracy of the test result. Therefore, the aforementioned saliva sampling device for one collection corresponding to one detection cannot meet the need for re-examination.

In addition, the saliva sampling and testing device in the prior art often fails to prompt whether the collected sample volume meets the requirement of the test volume, so that the subject cannot grasp the appropriate collection volume.

Summary of the invention

The purpose of the present invention is to overcome or at least alleviate the above-mentioned shortcomings in the prior art, and provide a saliva sampling device that can provide retest samples.

The present invention provides a saliva sampling and testing device, which includes a detection container and a sampling body, characterized in that the device further includes a liquid storage component, a transfer body and a sampling handle,

The liquid storage component includes liquid storage,

The liquid storage, the transfer body and the sampling body are used for absorbing saliva samples,

The sampling handle is cylindrical, and the sampling body is fixed to one end of the sampling handle and extends at least partially out of the sampling handle,

The liquid storage assembly can extend into the inner cavity of the sampling handle and be detachably fixedly installed and connected with the sampling handle,

The transfer body is accommodated in the inner cavity of the sampling handle and is in contact with the liquid storage and the sampling body respectively,

The sampling handle can extend into the inner cavity of the detection container, and make the sampling body squeeze the detection container to release the saliva sample.

In at least one embodiment, the sampling handle includes a first cylinder and a second cylinder that are sequentially connected in the axial direction, and the inner diameter of the first cylinder is larger than the inner diameter of the second cylinder,

The sampling body is fixed to the first cylinder, and the transfer body is at least partially contained in the inner cavity of the second cylinder.

In at least one embodiment, the sampling handle further includes a third cylinder connected to the second cylinder in the axial direction, and the liquid storage can be contained in the inner cavity of the third cylinder.

In at least one embodiment, the sampling handle further includes a locking cylinder, the inner peripheral wall of the locking cylinder has a locking structure detachably connected to the liquid storage assembly, and the outer peripheral wall of the locking cylinder has A locking structure detachably connected with the detection container.

In at least one embodiment, the sampling handle further includes a hand-held cylinder connected to the locking cylinder in the axial direction and located at the other end of the sampling handle, and the outer diameter of the hand-held cylinder is larger than that of the lock. The outer diameter of the closed cylinder.

In at least one embodiment, the liquid storage assembly further includes an indicator that can change color when exposed to water, and the indicator is installed at an end of the liquid storage away from the transfer body.

In at least one embodiment, the liquid storage assembly further includes a liquid storage fixing ring and a connecting column connected to each other,

The liquid storage is fixed to the fixing ring,

The connecting column has a hollow inner cavity, the indicator is accommodated in the inner cavity of the connecting column and is in contact with the liquid storage,

The connecting column has an area that is at least partially transparent.

In at least one embodiment, the liquid storage assembly further includes a locking ring and a hand-held part, the locking ring and the hand-held part are connected, and the locking ring and the hand-held part are connected to the connecting column far away from the Said one end of the fixed ring,

The outer peripheral wall of the locking ring has a locking structure detachably connected with the sampling handle,

The handle portion protrudes from the locking ring in the axial direction.

In at least one embodiment, the device further includes a sealing film, and the sealing film is hermetically fixed on the other end of the sampling handle away from the sampling body.

In at least one embodiment, the device further includes a first sealing ring and a second sealing ring,

The first sealing ring is fixed to the liquid storage assembly, and the first sealing ring is used to seal the radial gap between the liquid storage assembly and the sampling handle,

The second sealing ring is fixed to the other end of the sampling handle away from the sampling body, and the second sealing ring is used to seal the radial gap between the sampling handle and the detection container.

According to the saliva sampling and testing device of the present invention, through one collection process, two test samples can be provided to realize the functions of liquid storage and retesting.

Description of the drawings

Fig. 1 is an exploded schematic diagram of the saliva sampling device according to the present invention.

Fig. 2 is an axial sectional view of the saliva sampling device in Fig. 1 after being assembled.

Fig. 3 is a three-dimensional schematic diagram of the saliva sampling and inspection device in Fig. 1 after being assembled.

Fig. 4 is a schematic diagram of a liquid storage handle equipped with a first sealing ring according to an embodiment of the present invention.

Fig. 5 is a schematic diagram of a sampling handle equipped with a second sealing ring according to an embodiment of the present invention.

Description of reference signs

100 liquid storage handle; 101 locking ring; 102 sealing ring fixing ring; 103 liquid storage fixing ring; 104 connecting post; 105 hand-held part;

200 sampling handle; 201 first tube; 202 second tube; 203 third tube; 204 locking tube; 205 hand tube;

300 inspection container; 301 boss; 302 annular groove;

400 test paper jam; 401 test paper slot; 402 support part;

500 liquid storage; 600 transfer body; 700 sampling body; 800 indicator; 900 sealing film;

S1 first sealing ring; S2 second sealing ring.

Detailed ways

The exemplary embodiments of the present invention are described below with reference to the drawings. It should be understood that these specific descriptions are only used to teach those skilled in the art how to implement the present invention, not to exhaust all possible ways of the present invention, nor to limit the scope of the present invention.

Unless otherwise specified below, referring to FIG. 2, in other drawings and descriptions, A represents the axial direction of the saliva sampling device, and R represents the radial direction of the saliva sampling device.

1 to 3, the saliva sampling device according to the present invention includes a liquid storage handle 100, a sampling handle 200, a detection container 300, a test paper jam 400, a liquid storage 500, a transfer body 600, a sampling body 700, an indicator 800, The sealing film 900, the first sealing ring S1 and the second sealing ring S2.

The liquid storage handle 100, the indicator 800, the liquid storage 500, and the first sealing ring S1 are assembled together and participate in forming the liquid storage assembly.

The sampling handle 200, the transfer body 600, the sampling body 700, the second sealing ring S2 and the liquid storage assembly are assembled together and participate in forming the sampling assembly.

Preferably, the liquid storage 500, the transfer body 600 and the sampling body 700 are all composed of highly absorbent fibers and compressed into a cylindrical shape.

(Liquid storage component)

First, referring to Figure 1, Figure 2 and Figure 4, the basic structure of the liquid storage assembly is introduced.

The liquid storage handle 100 functions as a support in the liquid storage assembly, and is used to fix the indicator 800 and the liquid storage 500. The liquid storage handle 100 includes a locking ring 101, a sealing ring fixing ring 102, a liquid storing fixing ring 103, a connecting post 104 and a handle 105. The connecting column 104 sequentially connects the locking ring 101, the sealing ring fixing ring 102 and the liquid storing fixing ring 103 in the axial direction A.

The outer peripheral wall of the locking ring 101 has a locking structure for coupling with the locking structure of the inner peripheral wall of the locking cylinder 204 described below, so as to realize the connection between the liquid storage handle 100 and the sampling handle 200. Preferably, the locking structure of the outer peripheral wall of the locking ring 101 and the locking structure of the inner peripheral wall of the locking cylinder 204 are both threaded structures.

A handle 105 is connected to the inner cavity of the locking ring 101. Preferably, the holding portion 105 protrudes from the locking ring 101 in the axial direction, which is convenient for the operator to grasp the holding portion 105 to operate the liquid storage handle 100.

The sealing ring fixing ring 102 is connected to the outer circumference of the connecting column 104. The outer peripheral wall of the seal ring fixing ring 102 is recessed radially inward to form a recessed portion for fixing the first seal ring S1 (refer to FIG. 2).

The liquid storage fixing ring 103 is connected to the outer circumference of the end of the connecting column 104. Preferably, the liquid storage fixing ring 103 is in the shape of a lid, and the end of the liquid storage 500 is fixed to the inner cavity of the lid-shaped liquid storage fixing ring 103. Preferably, the liquid storage 500 is fixed to the liquid storage fixing ring 103 by dispensing and bonding.

The connecting column 104 is a hollow structure, and its inner cavity is used to accommodate the indicator 800. Preferably, the liquid storage handle 100 is a transparent piece, or at least has a partially transparent area at the connecting post 104, so that the color change of the indicator 800 can be easily recognized.

The indicator 800 and the liquid storage 500 are in contact with each other, for example, the indicator 800 and the liquid storage 500 are connected in contact at the ends, or the indicator 800 is embedded in the liquid storage 500. The indicator 800 is made of a water-absorbing material. For example, the indicator 800 is a color-changing test paper with different colors before and after absorbing water. When the liquid storage 500 absorbs a sufficient amount of saliva sample, the saliva will be further transferred to and absorbed by the indicator 800, and the indicator 800 will change color.

(Sampling component)

Next, referring to Figure 1, Figure 2 and Figure 5, the basic structure of the sampling assembly is introduced.

The sampling handle 200 functions as a support in the sampling assembly, and is used to fix the sampling body 700, the transfer body 600 and the liquid storage assembly.

The sampling handle 200 is in the shape of a hollow cylinder, which in the axial direction A includes a hand-held cylinder 205, a locking cylinder 204, a third cylinder 203, a second cylinder 202, and a first cylinder 201 in sequence.

The handheld barrel 205 is used for the operator to grasp to operate the assembly or disassembly of the sampling handle 200 and the detection container 300. Preferably, the outer peripheral wall of the hand barrel 205 has an inwardly recessed portion for fixing the second sealing ring S2. The second sealing ring S2 is used to seal the end of the detection container 300 in the radial space between the detection container 300 and the sampling handle 200 when the sampling handle 200 is installed on the detection container 300. Preferably, the outer diameter of the handheld barrel 205 is larger than the outer diameter of the locking barrel 204. After the locking barrel 204 is screwed into the detection container 300, the handheld barrel 205 is exposed from the detection container 300.

The outer wall of the locking cylinder 204 has a locking structure, which can cooperate with the locking structure on the inner wall of the detection container 300 to realize the connection between the sampling handle 200 and the detection container 300. Preferably, the locking structure of the outer wall of the locking cylinder 204 and the locking structure of the inner wall of the detection container 300 are both threaded structures.

The third cylinder 203 is used for containing the liquid storage 500, the second cylinder 202 is used for containing the transfer body 600, and the first cylinder 201 is used for containing the sampling body 700. The inner diameter of the second cylinder 202 is smaller than the inner diameter of the first cylinder 201.

Preferably, the inner diameter of the third cylinder 203 is slightly smaller than the outer diameter of the first sealing ring S1 in a natural state, so that after the liquid storage assembly and the sampling handle 200 are assembled together, the first sealing ring S1 is at the end of the third cylinder 203 Realize the sealing effect. The inner diameter of the third cylinder 203 is greater than the outer diameter of the liquid storage 500. When the liquid storage assembly and the sampling handle 200 are assembled together, the liquid storage 500 will not be squeezed by the second cylinder 202.

The first cylinder 201 has a cap shape, and the end of the sampling body 700 is fixed to the inner cavity of the cap-shaped first cylinder 201. Preferably, the sampling body 700 is fixed to the first cylinder 201 by means of glue dispensing.

Preferably, the outer diameter of the third cylinder 203 and the outer diameter of the first cylinder 201 are equal.

When assembling the liquid storage assembly and the sampling handle 200, for example, first put the transfer body 600 into the second barrel 202, and then screw the liquid storage handle 100 of the liquid storage assembly into the sampling handle 200. After the assembly is completed, the liquid storage 500 and the transfer body 600 are in close contact in the axial direction, and the transfer body 600 and the sampling body 700 are in close contact in the axial direction to ensure that the saliva absorbed by the sampling body 700 can be transferred to the storage through the transfer body 600. Liquid 500 places are stored.

The sampling body 700 protrudes from one end of the first cylinder 201 in a natural state, that is, when the sampling assembly is not assembled into the detection container, the axial length of the sampling body 700 is greater than the axial length of the first cylinder 201, and the subject The protruding end of the sampling body 700 can be placed in the mouth to collect saliva.

After the liquid storage assembly and the sampling handle 200 are assembled, the handle 105 of the liquid storage handle 100 is housed in the inner cavity of the communicating handle 205 and the locking barrel 204. At this time, the sealing film 900 is sealingly connected to the axial end of the hand barrel 205. The sealing film 900 is, for example, tin foil paper that is easy to tear. When the saliva sample stored in the liquid storage 500 needs to be used, the operator can tear off the sealing film 900, release the lock between the handle 105 and the locking cylinder 204, and take out the liquid storage assembly from the sampling handle 200.

(Saliva sampling device)

The sampling component including the liquid storage component, the detection container 300 and the test paper jam 400 together constitute the saliva sampling device according to the present invention.

1 to 3, the detection container 300 has a cylindrical shape with an open end. The middle part of the inner bottom surface of the detection container 300 protrudes toward the opening to form a boss 301 (refer to FIG. 2 ), thereby defining an annular groove 302 on the outer periphery of the boss 301.

1 and 2, the test paper stopper 400 has a cylindrical shape with open ends, and can be placed in the test container 300 in close contact with the inner wall of the test container 300. The outer peripheral wall of the test paper jam 400 defines a plurality of test paper slots 401 for storing test papers. One end of the test paper jam 400 has a plurality of supporting parts 402 in the axial direction. In other words, one end of the test paper jam 400 is uneven in the axial direction. Put the test paper jam 400 in the test container 300 with the support portion 402 facing inward. The support portion 402 will abut against the bottom of the annular groove 302 in the axial direction, and most of the annular groove 302 in the circumferential direction is not Will be filled up by the test paper jam 400. The space in the annular groove 302 provides a flow path for the saliva sample.

The inner diameter of the test paper jam 400 is equal to or slightly larger than the outer diameter of the third cylinder 203 and the outer diameter of the first cylinder 201.

2, after the liquid storage assembly is assembled in the detection container, the third tube 203, the second tube 202, and the first tube 201 of the sampling handle 200 are housed on the inner peripheral side of the test paper stopper 400, and the sampling body 700 contacts the boss 301 and Squeeze with the boss 301 to compress the sample body 700 in the axial direction. The saliva sample absorbed in the sample body 700 is squeezed and flows out. The saliva sample flows through the annular groove 302 and then contacts the test paper card holder 400. The test paper is tested to be tested.

Preferably, the side wall of the detection container 300 is transparent, so that the operator can easily observe the change of the detection test paper through the detection container 300.

During the compression of the sampling body 700, due to the axial limiting effect of the axial end of the first cylinder 201 on the sampling body 700, the transfer body 600 and the liquid storage 500 are hardly affected and deformed, especially The saliva sample stored in the liquid storage 500 will not flow out. Therefore, after the saliva sample stored in the sample body 700 completes one test, the saliva sample stored in the liquid storage 500 can also be used for the next test.

During the re-examination, by tearing off the sealing film 900, operating the handle 105 to take out the liquid storage assembly, for example, put the liquid storage assembly into the re-examination container and squeeze the saliva sample stored in the liquid storage 500 to form Perform a re-inspection.

The present invention has at least one of the following advantages:

(i) The sampling assembly of the present invention stores the saliva samples collected at one time in the separable sampling body 700 and the liquid storage 500 respectively, and through reasonable structural design, the operation process of taking the saliva samples in the sampling body 700 is different. It will affect the saliva sample in the liquid storage 500.

(ii) The color change of the indicator 800 can simply and clearly indicate whether the sampling volume meets the requirements, and improve the efficiency of the sampling process.

(iii) The sealing film 900 that is broken after tearing can prevent the liquid storage assembly from being removed in an unexpected situation, for example, when testing whether the subject is taking drugs, when the first test result of the sample is positive, the storage is required When the saliva sample in the liquid 500 is re-examined, it is not expected that unrelated persons will take out or even exchange the liquid 500 in advance to interfere with the re-examination result.

Of course, the present invention is not limited to the above-mentioned embodiments, and those skilled in the art can make various modifications to the above-mentioned embodiments of the present invention under the teaching of the present invention without departing from the scope of the present invention. E.g:

The indicator 800 may not be installed in the inner cavity of the connecting column 104, but directly fixed on the end of the liquid storage 500 away from the transfer body 600.

Claims (10)

A saliva sampling and testing device, which includes a detection container (300) and a sampling body (700), characterized in that the device also includes a liquid storage component, a transfer body (600) and a sampling handle (200), The liquid storage component includes a liquid storage (500), The liquid storage (500), the transfer body (600) and the sampling body (700) are used for absorbing saliva samples, The sampling handle (200) is cylindrical, and the sampling body (700) is fixed to one end of the sampling handle (200) and extends at least partially out of the sampling handle (200), The liquid storage assembly can extend into the inner cavity of the sampling handle (200) and be detachably fixedly installed and connected with the sampling handle (200), The transfer body (600) is contained in the inner cavity of the sampling handle (200) and is in contact with the liquid storage (500) and the sampling body (700) respectively, The sampling handle (200) can extend into the inner cavity of the detection container (300), and make the sampling body (700) squeeze the detection container (300) to release the saliva sample. The saliva sampling device according to claim 1, wherein the sampling handle (200) comprises a first tube (201) and a second tube (202) that are sequentially connected in the axial direction, and the first tube The inner diameter of (201) is greater than the inner diameter of the second cylinder (202), The sampling body (700) is fixed to the first cylinder (201), and the transfer body (600) is at least partially contained in the inner cavity of the second cylinder (202). The saliva sampling device according to claim 2, characterized in that, the sampling handle (200) further comprises a third tube (203), and the third tube (203) is axially aligned with the second tube (202) is connected, and the liquid storage (500) can be contained in the inner cavity of the third cylinder (203). The saliva sampling device according to claim 1, wherein the sampling handle (200) further comprises a locking cylinder (204), and the inner peripheral wall of the locking cylinder (204) is provided with the liquid storage assembly A detachably connected locking structure, the outer peripheral wall of the locking cylinder (204) has a locking structure detachably connected to the detection container (300). The saliva sampling device according to claim 4, characterized in that the sampling handle (200) further comprises another part connected to the locking cylinder (204) in the axial direction and located on the sampling handle (200). One end of the handheld barrel (205), the outer diameter of the handheld barrel (205) is larger than the outer diameter of the locking barrel (204). The saliva sampling device according to claim 1, wherein the liquid storage assembly further comprises an indicator (800) that can change color when exposed to water, and the indicator (800) is installed on the liquid storage (500). ) Away from the end of the transfer body (600). The saliva sampling device according to claim 6, characterized in that the liquid storage assembly further comprises a liquid storage fixing ring (103) and a connecting column (104) connected to each other, The liquid storage (500) is fixed to the fixing ring (103), The connecting column (104) has a hollow inner cavity, and the indicator (800) is accommodated in the inner cavity of the connecting column (104) and is in contact with the liquid storage (500), The connecting pillar (104) has an area that is at least partially transparent. The saliva sampling device according to claim 7, characterized in that the liquid storage assembly further comprises a locking ring (101) and a hand-held part (105), the locking ring (101) and the hand-held part (105) Connected, and the locking ring (101) and the handle (105) are connected to an end of the connecting column (104) far from the fixing ring (103), The outer peripheral wall of the locking ring (101) has a locking structure detachably connected with the sampling handle (200), The handle (105) protrudes from the locking ring (101) in the axial direction. The saliva sampling device according to claim 1, wherein the device further comprises a sealing film (900), and the sealing film (900) is hermetically fixed on the sampling handle (200) away from the sampling The other end of the body (700). The saliva sampling and inspection device according to claim 1, wherein the device further comprises a first sealing ring (S1) and a second sealing ring (S2), The first sealing ring (S1) is fixed to the liquid storage assembly, and the first sealing ring (S1) is used to seal the radial gap between the liquid storage assembly and the sampling handle (200), The second sealing ring (S2) is fixed to the other end of the sampling handle (200) away from the sampling body (700), and the second sealing ring (S2) is used to seal the sampling handle ( 200) and the radial gap between the detection container (300).

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