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WO2020214220A3 - Cannabinoid systems and methods: water-solubility, targeting, and augmentation - Google Patents

Cannabinoid systems and methods: water-solubility, targeting, and augmentation Download PDF

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Publication number
WO2020214220A3
WO2020214220A3 PCT/US2020/013765 US2020013765W WO2020214220A3 WO 2020214220 A3 WO2020214220 A3 WO 2020214220A3 US 2020013765 W US2020013765 W US 2020013765W WO 2020214220 A3 WO2020214220 A3 WO 2020214220A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
augmentation
targeting
solubility
water
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2020/013765
Other languages
French (fr)
Other versions
WO2020214220A2 (en
Inventor
John C. GUSTIN
Michael J. Mccarthy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2020214220A2 publication Critical patent/WO2020214220A2/en
Publication of WO2020214220A3 publication Critical patent/WO2020214220A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/658—Medicinal preparations containing organic active ingredients o-phenolic cannabinoids, e.g. cannabidiol, cannabigerolic acid, cannabichromene or tetrahydrocannabinol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05—Phenols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/348—Cannabaceae
    • A61K36/3482—Cannabis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention describes compositions, and associated methods, comprising a cannabinoid operably linked with a biologically active agent for augmented cannabinoid agents.
PCT/US2020/013765 2019-01-15 2020-01-15 Cannabinoid systems and methods: water-solubility, targeting, and augmentation Ceased WO2020214220A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201962792898P 2019-01-15 2019-01-15
US62/792,898 2019-01-15
US201962803406P 2019-02-08 2019-02-08
US62/803,406 2019-02-08

Publications (2)

Publication Number Publication Date
WO2020214220A2 WO2020214220A2 (en) 2020-10-22
WO2020214220A3 true WO2020214220A3 (en) 2020-11-26

Family

ID=72837544

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2020/013765 Ceased WO2020214220A2 (en) 2019-01-15 2020-01-15 Cannabinoid systems and methods: water-solubility, targeting, and augmentation

Country Status (1)

Country Link
WO (1) WO2020214220A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA3157998A1 (en) * 2019-10-15 2021-04-22 Diverse Biotech, Inc. Conjugate molecules
US11660348B1 (en) 2022-02-01 2023-05-30 Akos Biosciences, Inc. Cannabinoid conjugate molecules
US11883499B2 (en) 2022-02-01 2024-01-30 Akos Biosciences, Inc. Cannabinoid conjugate molecules

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302703A (en) * 1992-04-06 1994-04-12 Biosite Diagnostics Incorporated Tetrahydrocannabinol derivatives and protein and polypeptide tetrahydrocannabinol derivative conjugates and labels
US20150265720A1 (en) * 2014-03-18 2015-09-24 Izun Pharmaceuticals Corp. Water-based cannabinoid and opioid compositions
WO2017183011A1 (en) * 2016-04-22 2017-10-26 Degeeter David M Water soluble cannabinoid inclusion complexes
WO2018163187A1 (en) * 2017-03-09 2018-09-13 Izun Pharmaceuticals Corp. Stabilized protein-bound cannabinoid compositions
US20200254104A1 (en) * 2019-02-11 2020-08-13 John CHANCEY Methods of making and using phytocannabinoids complexed with a protein, peptide, amino acid, polysaccharide, disacchride, or monosaccharide

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5302703A (en) * 1992-04-06 1994-04-12 Biosite Diagnostics Incorporated Tetrahydrocannabinol derivatives and protein and polypeptide tetrahydrocannabinol derivative conjugates and labels
US20150265720A1 (en) * 2014-03-18 2015-09-24 Izun Pharmaceuticals Corp. Water-based cannabinoid and opioid compositions
WO2017183011A1 (en) * 2016-04-22 2017-10-26 Degeeter David M Water soluble cannabinoid inclusion complexes
WO2018163187A1 (en) * 2017-03-09 2018-09-13 Izun Pharmaceuticals Corp. Stabilized protein-bound cannabinoid compositions
US20200254104A1 (en) * 2019-02-11 2020-08-13 John CHANCEY Methods of making and using phytocannabinoids complexed with a protein, peptide, amino acid, polysaccharide, disacchride, or monosaccharide

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
KARKOS ET AL.: "Spirulina in Clinical Practice: Evidence-Based Human Applications", EVIDENCE- BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, vol. 2011, 19 October 2010 (2010-10-19), pages 1 - 4, XP055761656 *
QI ET AL.: "Biomaterials as carrier, barrier and reactor for cell -based regenerative medicine", PROTEIN & CELL, vol. 6, 19 June 2015 (2015-06-19), pages 638 - 653, XP055714765, DOI: 10.1007/s13238-015-0179-8 *

Also Published As

Publication number Publication date
WO2020214220A2 (en) 2020-10-22

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