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WO2020209460A1 - Structure de revêtement poreux et procédé de fabrication d'une structure de revêtement poreux - Google Patents

Structure de revêtement poreux et procédé de fabrication d'une structure de revêtement poreux Download PDF

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Publication number
WO2020209460A1
WO2020209460A1 PCT/KR2019/015613 KR2019015613W WO2020209460A1 WO 2020209460 A1 WO2020209460 A1 WO 2020209460A1 KR 2019015613 W KR2019015613 W KR 2019015613W WO 2020209460 A1 WO2020209460 A1 WO 2020209460A1
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WIPO (PCT)
Prior art keywords
porous structure
porous
coating
bonding
pores
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2019/015613
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English (en)
Korean (ko)
Inventor
임도형
곽태양
반훈영
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Industry Academy Cooperation Foundation of Sejong University
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Industry Academy Cooperation Foundation of Sejong University
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Publication date
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Publication of WO2020209460A1 publication Critical patent/WO2020209460A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2/30942—Designing or manufacturing processes for designing or making customized prostheses, e.g. using templates, CT or NMR scans, finite-element analysis or CAD-CAM techniques
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/3092—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth having an open-celled or open-pored structure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/3093—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth for promoting ingrowth of bone tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2002/30934—Special articulating surfaces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2002/30967—Diffusion bonding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/18—Modification of implant surfaces in order to improve biocompatibility, cell growth, fixation of biomolecules, e.g. plasma treatment
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2430/00—Materials or treatment for tissue regeneration
    • A61L2430/24—Materials or treatment for tissue regeneration for joint reconstruction

Definitions

  • the present invention relates to a porous coating structure and a method of manufacturing a porous coating structure, and more particularly, to a porous coating structure and a method of manufacturing a porous coating structure that can be applied to an orthopedic implant with improved osseointegration.
  • the artificial joint may be represented as an orthopedic implant, and the orthopedic implant generally promotes bone growth, that is, osteosynthesis, through a coating of a porous structure on the implant base.
  • Orthopedic implants in which a coating layer having a porous structure is formed can be manufactured by various methods such as diffusion bonding disclosed in Japanese Patent Application Laid-Open No. 2008-194463.
  • the conventional diffusion bonding method as described above decreases the porosity around the surface of the coating layer, thereby reducing the degree of osseointegration, and at the same time, does not guarantee the bonding strength between the coating layer and the implant base, resulting in a serious problem of mass production of defective products. Will cause.
  • the porous coating structure according to an embodiment of the present invention is a structure manufactured by diffusion bonding a porous structure to a non-porous structure, and the non-porous structure of a metal component.
  • a base part implemented; Diffusion bonding between the base portion and the porous structure of a metal component-The diffusion bonding is a bonding made by pressing the base portion-A coating portion formed on at least a part of the surface of the base portion by-The coating portion, the diffusion bonding When formed by the porous structure -;
  • a connection securing unit formed by penetrating into the pores during the diffusion bonding in order to prevent the connectivity between the pores previously formed in the porous structure from being degraded by the diffusion bonding.
  • connection securing part of the porous coating structure may be characterized in that it improves corrosion resistance and abrasion resistance by coating an inner surface defining the void.
  • connection securing part of the porous coating structure may include the non-porous structure and a powder non-reactive with the porous structure.
  • connection securing unit of the porous coating structure may include at least one of ceramic powder, oxide powder, and nitride powder.
  • connection securing unit of the porous coating structure in order to prevent the pores from being closed by penetration during the diffusion bonding, a melting point higher than at least one of the porous structure and the non-porous structure It may be characterized by having a.
  • the coating portion of the porous coating structure according to an embodiment of the present invention may be characterized in that the porosity increases in a direction from the bonding surface with the base portion toward the surface.
  • the surface of the porous structure is the opposite side of the bonding surface between the porous structure and the non-porous structure.
  • a porosity of the periphery of the surface of the porous structure may be greater than that of the periphery of the bonding surface.
  • connection securing unit of the porous coating structure is distributed only around the surface of the coating unit-the surface of the coating unit is an opposite surface of the bonding surface of the coating unit and the base unit. It may be characterized in that the porosity of the periphery of the negative surface is greater than the porosity of the periphery of the bonding surface.
  • the base portion of the porous coating structure according to an embodiment of the present invention is a parent body for a living body implant, and the coating part is formed on at least a part of the surface of the parent body of the bio-implant, and the connection between the pores is secured to prevent osseointegration. It can be characterized by improving.
  • a method of manufacturing a porous coating structure according to another embodiment of the present invention is a porous coating structure by bonding a porous structure of a metal component to a non-porous structure of a metal component.
  • a method of manufacturing comprising: a first step of placing the non-porous structure and the porous structure in a vacuum chamber of a vacuum furnace for bonding; And a second step of pressing the non-porous structure with a pressure applying portion disposed in the vacuum chamber to form a diffusion bonding between the non-porous structure and the porous structure, wherein the first step is located in the vacuum chamber.
  • the porous structure and the non-porous After filling a powder for preventing the connectivity between the pores previously formed in the porous structure from being lowered by the second step in which the diffusion bonding is performed on the supporting structure, the porous structure and the non-porous It includes the step of sequentially arranging the structure, the second step, the step of pressing the non-porous structure to a predetermined pressure by the pressure applying unit under a predetermined temperature, so that the powder penetrates into the pores. It may be characterized by including.
  • the powder of the method of manufacturing a porous coating structure according to another embodiment of the present invention is a material that does not react with the non-porous structure and the porous structure, and penetrates into the pores to prevent the pores from being closed. It has a melting point higher than at least one of the porous structure and the non-porous structure, and the predetermined temperature may be a temperature lower than the melting point.
  • the predetermined pressure in the method of manufacturing a porous coating structure according to another embodiment of the present invention is, when the powder proceeds to the second step, the surface of the porous structure-the surface of the porous structure is, the porous structure and the ratio It may be characterized in that it is determined within a range such that the porosity for the periphery of the surface of the porous structure is greater than the porosity for the periphery of the bonding surface by penetrating into the pores from the surface opposite to the bonding surface of the porous structure. have.
  • the predetermined pressure in the method for manufacturing a porous coating structure according to another embodiment of the present invention is, wherein the powder is the surface of the porous structure-the surface of the porous structure is a bonding surface between the porous structure and the non-porous structure It is the opposite side of-Distributed only around the periphery of, it may be characterized in that it is determined within a range such that the porosity of the periphery of the surface of the porous structure is greater than the porosity of the periphery of the bonding surface.
  • the method of manufacturing the porous coating structure and the porous coating structure according to the present invention it is possible to provide an orthopedic implant with improved corrosion resistance and abrasion resistance, as well as ensuring connectivity between pores.
  • FIG. 1 is a flow chart illustrating a method of manufacturing a porous coating structure according to an embodiment of the present invention.
  • FIGS. 2 to 6 are views for explaining a method of manufacturing a porous coating structure according to an embodiment of the present invention.
  • the porous coating structure according to an embodiment of the present invention is a structure manufactured by diffusion bonding a porous structure to a non-porous structure, and the non-porous structure of a metal component.
  • a base part implemented; Diffusion bonding between the base portion and the porous structure of a metal component-The diffusion bonding is a bonding made by pressing the base portion-A coating portion formed on at least a part of the surface of the base portion by-The coating portion, the diffusion bonding When formed by the porous structure -;
  • a connection securing unit formed by penetrating into the pores during the diffusion bonding in order to prevent the connectivity between the pores previously formed in the porous structure from being degraded by the diffusion bonding.
  • FIGS. 2 to 6 are diagrams for explaining a method of manufacturing a porous coating structure according to an embodiment of the present invention .
  • the porous coating structure according to the present invention is a structure in which a metal-based porous structure 200 is present as a coating layer on at least a part of the surface of a metal-based non-porous structure, for example, orthopedic surgery It can be applied to implants.
  • the porous coating structure is formed between the base part implemented as the non-porous structure, the coating part formed on at least a part of the surface of the base part by diffusion bonding between the base part and the porous structure, and pores previously formed in the porous structure.
  • it may include a connection securing unit formed by penetrating into the void during the diffusion bonding.
  • porous coating structure including the above components
  • porous coating structure manufactured by this manufacturing method will be additionally described.
  • the method of manufacturing a porous coating structure is to fill (S12) the powder 100 on the support structure 14 located in the vacuum chamber 12 of the vacuum furnace 10, and In the first step (S10) of sequentially placing (S14, S16) the porous structure 200 and the non-porous structure 300 and the non-porous structure with the pressure applying unit 16 disposed in the vacuum chamber 12 A second step (S20) of performing diffusion bonding between 300 and the porous structure 200 may be included.
  • FIGS. 2 to 6 will be described in detail with respect to the above steps.
  • the powder 100 is filled on the support structure 14 located in the vacuum chamber 12 of the vacuum furnace 10 to manufacture a porous coating structure that can be applied to an orthopedic implant. (S12).
  • the vacuum chamber 12 of the vacuum furnace 10 may maintain a vacuum state for diffusion bonding, and the vacuum chamber 12 may be in an atmosphere state of a predetermined temperature.
  • the vacuum furnace 10 may include a pressure applying unit 16 capable of applying pressure to the non-porous structure 300, and the pressure applying unit 16 is a non-porous structure as shown in FIG. By applying pressure to 300, physical surface contact may occur between the non-porous structure 300 and the porous structure 200.
  • the support structure 14 may have sidewalls to prevent the powder 100 from spreading to the vacuum chamber 12 other than the support structure 14, whereby the powder 100 is stably described later. It constitutes the connection security unit.
  • the powder 100 is used in the second step (S20) in order to prevent the connectivity between the pores formed in advance in the porous structure 200 from being degraded by the second step (S20) in which the diffusion bonding is performed. It is a powder that penetrates into the voids, and finally constitutes a connection securing part, which is a component of the porous coating structure.
  • the powder 100 is a powder that does not react with the non-porous structure 300 and the porous structure 200 and may include at least one of a ceramic powder, an oxide powder, and a nitride powder.
  • a melting point higher than at least one of the porous structure 200 and the non-porous structure 300 may be provided so as to prevent the pores from being closed by penetrating the pores.
  • the porous structure 200 and the Steps (S14, S16) of sequentially arranging the non-porous structure 300 may be performed to complete the first step (S10).
  • the porous structure 200 is a structure for coating at least a portion of the surface of the non-porous structure 300 and constitutes a coating part, which is a component of the porous coating structure.
  • the porous structure 200 may be a metal containing a metal component, for example, titanium (Ti) as a main component, and may have numerous voids.
  • a metal component for example, titanium (Ti) as a main component, and may have numerous voids.
  • the pores of the porous structure 200 are connected to each other, and these pores serve as an element to improve osteosynthesis when the porous coating structure according to the present invention is applied to an orthopedic implant.
  • the porous structure 200 may be manufactured by various methods, for example, may be manufactured by 3D printing, and when the porous coating structure according to the present invention is applied to an orthopedic implant, it is suitable for the structure of the bone used. It can be implemented in various shapes.
  • the porosity of the porous structure 200 may be freely adjustable in the process of manufacturing the porous structure 200.
  • the non-porous structure 300 may function as an implant base, and may be implemented in various shapes according to the structure of the bone used.
  • the non-porous structure 300 may be a metal containing a metal component, for example, cobalt chromium (CoCr) as a main component.
  • a metal component for example, cobalt chromium (CoCr) as a main component.
  • the temperature in the vacuum chamber 12 is raised to a predetermined temperature, and the non-porous structure 300 is pressurized by a pressure applying unit 16 disposed in the vacuum chamber 12.
  • a second step (S20) of diffusion bonding between the porous structure 300 and the porous structure 200 may be performed.
  • the non-porous structure 300 is pressed with a predetermined pressure by the pressure applying unit 16 under a predetermined temperature, so that the powder 100 is formed into the pores of the porous structure 200. It may include the step of penetrating into.
  • diffusion bonding is a method of bonding materials that are atomically bonded using heat and pressure. A metal material is adhered to each other, heating the material to a temperature below the melting point, and applying pressure so as not to cause plastic deformation between the bonding surfaces. It may mean a method of bonding using the diffusion of atoms occurring in
  • the powder 100 is a material that does not react with the non-porous structure 300 and the porous structure 200 and penetrates into the pores of the porous structure 200 to prevent the pores from being closed, It may have a higher melting point than at least one of the porous structure 200 and the non-porous structure 300, and a predetermined temperature in the vacuum chamber 12 in which the second step (S20) is performed is lower than the melting point. It can be temperature.
  • the predetermined pressure applied by the pressure applying unit 16 penetrates the pores of the porous structure 200 from the surface of the porous structure 200 when the powder 100 proceeds with the second step (S20).
  • the porosity of the periphery of the surface of the porous structure 200 may be determined within a range that is greater than the porosity of the periphery of the bonding surface.
  • the surface of the porous structure 200 is a surface opposite to the bonding surface of the porous structure 200 and the non-porous structure 300.
  • the predetermined pressure is distributed only in the periphery of the surface of the porous structure 200, so that the porosity of the periphery of the porous structure 200 is not greater than that of the periphery of the bonding surface. It can be determined within the range to allow.
  • the second step (S20) proceeds as described above, at least a part of the surface of the non-porous structure 300 is coated with the porous structure 200, and the porous structure 200 due to the powder 100 The connectivity of the voids is ensured, and a porous coating structure with improved osseointegration is manufactured.
  • the second step (S20) presses the non-porous structure 300 with the pressure applying unit 16 under a predetermined temperature for diffusion bonding between the porous structure 200 and the non-porous structure 300 as described above.
  • the connectivity between the pores of the porous structure 200 is deteriorated, and the porous structure 200 that is a surface opposite to the bonding surface of the porous structure 200 and the non-porous structure 300
  • the problem of lowering the porosity around the surface of) can be effectively solved by the powder 100 penetrating the pores.
  • the porous structure before diffusion bonding, the porous structure is already formed by connecting numerous pores, but when diffusion bonding between the porous structure and the non-porous structure, due to the characteristics of diffusion bonding, the pores around the surface become small and the porosity decreases. It has to be.
  • the porous structure 200 and the non-porous structure 300 are bonded to each other by diffusion bonding, but the problem caused by diffusion bonding is solved by the powder 100 on the support structure 14 in the vacuum chamber 12.
  • the powder penetrates into the pores formed around the surface of the porous structure 200 during diffusion bonding, thereby preventing a reduction in the size of the pores and performing a kind of spacer function to secure connectivity between the pores.
  • the powder 100 may penetrate into the pores and coat the inner surface defining the pores, thereby greatly improving corrosion resistance and abrasion resistance.
  • the step of separating the porous coating structure from the vacuum furnace 10 (S30) proceeds, and when optionally subjected to a post-treatment process, the porous coating structure can be finally used as an orthopedic implant.
  • the porous coating structure manufactured by the manufacturing method as described above may include a base part implemented as a non-porous structure, a coating part implemented as the porous structure 200, and a connection security part implemented by the powder 100.
  • the base portion may be a parent body for a biological implant, and the coating part may be formed on at least a part of a surface of the parent body of the implant for a living body, and may be a component for improving osseointegration by securing connectivity between voids.
  • the connectivity securing unit may penetrate into the pores previously formed in the porous structure 200 during diffusion bonding to prevent a decrease in connectivity between the pores, and is attached to at least a portion of the inner surface defining the pores to produce an effect of coating at least a portion of the pores. I can.
  • the porous coating structure according to the present invention may have improved corrosion resistance and abrasion resistance.
  • the coating portion may increase the porosity in the direction from the base portion and the bonding surface toward the surface of the coating portion. Accordingly, when the porous coating structure is used as an orthopedic implant, it improves bone adhesion and at the same time around the bonding surface.
  • the porosity of is formed to be small so that the bonding force with the base portion can be maximized.
  • the connectivity securing unit may be distributed only in a portion of the pores of the coating unit, that is, the periphery of the surface of the coating unit, whereby the porosity of the periphery of the coating unit may be greater than the porosity of the periphery of the bonding surface. .

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  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Inorganic Chemistry (AREA)
  • Manufacturing & Machinery (AREA)
  • Geometry (AREA)
  • Physics & Mathematics (AREA)
  • Dispersion Chemistry (AREA)
  • Prostheses (AREA)

Abstract

Une structure de revêtement poreux selon un mode de réalisation de la présente invention est une structure fabriquée par liaison par diffusion d'une structure poreuse à une structure non poreuse, et peut comprendre : une partie base formée à partir de la structure non poreuse composée d'un constituant métallique ; une partie revêtement formée sur au moins une partie de la surface de la partie base par liaison par diffusion entre la partie base et la structure poreuse composée d'un constituant métallique, la liaison par diffusion étant obtenue par pression de la partie base, et la partie revêtement étant formée à partir de la structure poreuse pendant la liaison par diffusion ; et une partie de fixation de connectivité qui est formée pendant la liaison par diffusion en pénétrant dans des pores qui sont préformés dans la structure poreuse, afin d'empêcher la dégradation de la connectivité entre les pores par la liaison par diffusion.
PCT/KR2019/015613 2019-04-11 2019-11-15 Structure de revêtement poreux et procédé de fabrication d'une structure de revêtement poreux Ceased WO2020209460A1 (fr)

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KR1020190042428A KR102014808B1 (ko) 2019-04-11 2019-04-11 다공성 코팅 구조체 및 다공성 코팅 구조체 제조 방법
KR10-2019-0042428 2019-04-11

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KR102014808B1 (ko) * 2019-04-11 2019-08-27 세종대학교산학협력단 다공성 코팅 구조체 및 다공성 코팅 구조체 제조 방법

Citations (6)

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JP2004041726A (ja) * 2002-06-18 2004-02-12 Zimmer Inc 多孔性金属層を金属の基体に付着させる方法
JP2008194463A (ja) * 2007-02-09 2008-08-28 Zimmer Technology Inc 整形外科インプラントで使用する基体材料に多孔性コーティングを接合するための直接加圧
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JP2014091151A (ja) * 2012-11-05 2014-05-19 Mitsubishi Materials Corp 多孔質複合金属体の製造方法及び製造装置
KR102014808B1 (ko) * 2019-04-11 2019-08-27 세종대학교산학협력단 다공성 코팅 구조체 및 다공성 코팅 구조체 제조 방법

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