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WO2020254844A3 - Hydrophilic microbial cellulose containing carrier substance (gel) for improving the condition of the intestinal mucosa - Google Patents

Hydrophilic microbial cellulose containing carrier substance (gel) for improving the condition of the intestinal mucosa Download PDF

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Publication number
WO2020254844A3
WO2020254844A3 PCT/HU2020/000021 HU2020000021W WO2020254844A3 WO 2020254844 A3 WO2020254844 A3 WO 2020254844A3 HU 2020000021 W HU2020000021 W HU 2020000021W WO 2020254844 A3 WO2020254844 A3 WO 2020254844A3
Authority
WO
WIPO (PCT)
Prior art keywords
gel
carrier substance
microbial cellulose
improving
condition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/HU2020/000021
Other languages
French (fr)
Other versions
WO2020254844A2 (en
Inventor
Zoltán HUMMEL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2020254844A2 publication Critical patent/WO2020254844A2/en
Publication of WO2020254844A3 publication Critical patent/WO2020254844A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38—Cellulose; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66—Microorganisms or materials therefrom
    • A61K35/74—Bacteria
    • A61K35/741—Probiotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

This invention pertains to a hydrophilic microbial cellulose containing carrier substance (gel) for improving the condition of the intestinal mucosa. The carrier substance is characterised in that that, as a medium, it is capable of introducing high levels of substances useful to the body, such that in its composition, that is, in a gel consisting of 100 g of microbial cellulose fibres, is found, by way of pulping, a network of amorphous fibres at least 5% of which have a particle size of 500 nm, which network consists of nanofibres 1-2 nm in thickness and 50-60 nm in width. Because their surfaces are hydrophilic, these nanofibres are capable of retaining large quantities of water and are therefore well-adapted to adsorbing probiotics, active chemical ingredients, and active hydrogen for introduction into the mucosa of the large intestine.
PCT/HU2020/000021 2019-06-21 2020-06-19 Hydrophilic microbial cellulose containing carrier substance (gel) for improving the condition of the intestinal mucosa Ceased WO2020254844A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUP1900226 2019-06-21
HU1900226A HUP1900226A1 (en) 2019-06-21 2019-06-21 Carrier (gel) containing hydrophilic microbial cellulose nanofibers to impruve intestinal mucosa condition

Publications (2)

Publication Number Publication Date
WO2020254844A2 WO2020254844A2 (en) 2020-12-24
WO2020254844A3 true WO2020254844A3 (en) 2021-04-08

Family

ID=89992930

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/HU2020/000021 Ceased WO2020254844A2 (en) 2019-06-21 2020-06-19 Hydrophilic microbial cellulose containing carrier substance (gel) for improving the condition of the intestinal mucosa

Country Status (2)

Country Link
HU (1) HUP1900226A1 (en)
WO (1) WO2020254844A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2567942A2 (en) * 2010-05-03 2013-03-13 Kim, Ilbong Portable hydrogen-rich water generator
US20130330379A1 (en) * 2010-10-27 2013-12-12 Upm-Kymmene Corporation Drug delivery compositions
US20140322327A1 (en) * 2011-11-15 2014-10-30 Upm-Kymmene Corporation Drug delivery system for sustained delivery of bioactive agents
WO2017141064A1 (en) * 2016-02-18 2017-08-24 Zoltan Hummel Process for the high-efficiency hydration of gut flora in the colon

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2567942A2 (en) * 2010-05-03 2013-03-13 Kim, Ilbong Portable hydrogen-rich water generator
US20130330379A1 (en) * 2010-10-27 2013-12-12 Upm-Kymmene Corporation Drug delivery compositions
US20140322327A1 (en) * 2011-11-15 2014-10-30 Upm-Kymmene Corporation Drug delivery system for sustained delivery of bioactive agents
WO2017141064A1 (en) * 2016-02-18 2017-08-24 Zoltan Hummel Process for the high-efficiency hydration of gut flora in the colon

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ADEBAYO OLAJUMOKE: "EVALUATION OF BACTERIAL POLYMERS AS PROTECTIVE AGENTS FOR SENSITIVE PROBIOTIC BACTERIA", 1 February 2018 (2018-02-01), pages 1 - 295, XP055774834, Retrieved from the Internet <URL:https://wlv.openrepository.com/bitstream/handle/2436/621096/Adebayo%20PhD%20Thesis.pdf?sequence=1&isAllowed=y> [retrieved on 20210210] *
DIMA STEFAN-OVIDIU ET AL: "Bacterial Nanocellulose from Side-Streams of Kombucha Beverages Production: Preparation and Physical-Chemical Properties", POLYMERS, vol. 9, no. 12, 18 August 2017 (2017-08-18), pages 374, XP055775227, Retrieved from the Internet <URL:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418918/pdf/polymers-09-00374.pdf> DOI: 10.3390/polym9080374 *
MACKIE ALAN R. ET AL: "Sodium alginate decreases the permeability of intestinal mucus", FOOD HYDROCOLLOIDS, vol. 52, 1 January 2016 (2016-01-01), NL, pages 749 - 755, XP055775514, ISSN: 0268-005X, DOI: 10.1016/j.foodhyd.2015.08.004 *

Also Published As

Publication number Publication date
HUP1900226A1 (en) 2020-12-28
WO2020254844A2 (en) 2020-12-24

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